Compounds > 1-propargyl-5-chloropyrimidin-2-one
Page last updated: 2024-09-03

1-propargyl-5-chloropyrimidin-2-one and pyrimidinones

1-propargyl-5-chloropyrimidin-2-one has been researched along with pyrimidinones in 7 studies

Compound Research Comparison

Studies
(1-propargyl-5-chloropyrimidin-2-one)		Trials
(1-propargyl-5-chloropyrimidin-2-one)		Recent Studies (post-2010)
(1-propargyl-5-chloropyrimidin-2-one)		Studies
(pyrimidinones)		Trials
(pyrimidinones)		Recent Studies (post-2010) (pyrimidinones)
8006,0596042,692

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19907 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Oftebro, R; Wibe, E2
Dornish, JM; Nygaard, ME; Oftebro, R; Pettersen, EO1
Dornish, JM; Oftebro, R; Pettersen, EO2
Adams, K; Anderson, M; Brewer, F; Warr, JR1
Wibe, E1

Other Studies

7 other study(ies) available for 1-propargyl-5-chloropyrimidin-2-one and pyrimidinones

ArticleYear
Inactivation by the mitotic inhibitor NY 3170 of human cells in vitro.
    British journal of cancer, 1979, Volume: 40, Issue:2

    Topics: Cell Cycle; Cell Survival; Cells, Cultured; Humans; Metaphase; Mitosis; Pyrimidinones; Time Factors

1979
Sulfhydryl-related reduction of the mitotic inhibition and cell inactivation induced by pyrimidine analogs.
    Anti-cancer drug design, 1988, Volume: 3, Issue:1

    Topics: Cell Cycle; Cell Line; Cell Survival; Chemical Phenomena; Chemistry; Cysteine; Cystine; Glutathione; Humans; Mitosis; Mitotic Index; Pyrimidines; Pyrimidinones; Sulfhydryl Compounds

1988
Synergistic cell inactivation by cis-dichlorodiammineplatinum in combination with 1-propargyl-5-chloropyrimidin-2-one.
    British journal of cancer, 1987, Volume: 56, Issue:3

    Topics: Cell Cycle; Cell Line; Cell Survival; Cisplatin; Dose-Response Relationship, Drug; Drug Synergism; Humans; Mitosis; Pyrimidinones; Time Factors

1987
Interaction of 1-propargyl-5-chloropyrimidin-2-one (a metahalone) with rat brain tubulin.
    Biochimica et biophysica acta, 1984, Feb-14, Volume: 797, Issue:2

    Topics: Animals; Binding Sites; Brain; Kinetics; Macromolecular Substances; Protein Binding; Pyrimidinones; Rats; Spectrometry, Fluorescence; Tubulin; Vincristine

1984
Resistance to the mitotic inhibitor NY 3170 in Chinese hamster ovary cells.
    Cell biology international reports, 1984, Volume: 8, Issue:7

    Topics: Animals; Cell Line; Cell Survival; Cricetinae; Cricetulus; Drug Resistance; Female; Kinetics; Mitosis; Mutation; Ovary; Pyrimidinones; Structure-Activity Relationship

1984
A study of factors related to the action of 1-propargyl-5-chloropyrimidin-2-one (NY 3170) and vincristine in human multicellular spheroids.
    European journal of cancer & clinical oncology, 1981, Volume: 17, Issue:9

    Topics: Carcinoma in Situ; Cell Line; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Drug Resistance; Female; Humans; Mitotic Index; Pyrimidinones; Uterine Cervical Neoplasms; Vincristine

1981
Age-dependent cell inactivation by vincristine alone or in combination with 1-propargyl-5-chloropyrimidin-2-one.
    Cancer research, 1980, Volume: 40, Issue:6

    Topics: Cell Survival; Cells, Cultured; Drug Resistance; Drug Synergism; Female; Humans; Interphase; Mitosis; Pyrimidinones; Vincristine

1980