1-phenyl-2-decanoylamino-3-morpholino-1-propanol and sphingosine

1-phenyl-2-decanoylamino-3-morpholino-1-propanol has been researched along with sphingosine in 20 studies

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19901 (5.00)18.7374
1990's7 (35.00)18.2507
2000's10 (50.00)29.6817
2010's2 (10.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Brady, RO; Brown, A; Comly, ME; Cooney, A; Goldin, E; Miller, SP; Pentchev, PG; Roff, CF; Vanier, MT1
Felding-Habermann, B; Fenderson, BA; Hakomori, S; Handa, K; Igarashi, Y; Inokuchi, J; Park, LS; Radin, NS; Strassmann, G1
Radin, NS; Vunnam, RR1
Goto, I; Kobayashi, T; Sasagasako, N; Yamaguchi, Y1
Hamanoue, M; Inokuchi, J; Kohsaka, S; Usuki, S1
Inokuchi, J; Kuriyama, M; Mutoh, T; Tokuda, A1
Hirabayashi, Y; Inokuchi, J; Ito, M; Ji, L; Yamagata, T; Zhang, G1
Cryer, HG; Fu, M; Lo, CJ; Lo, FR1
Fukunaga, T; Hatsuzawa, K; Nagahama, M; Tagaya, M; Tani, K; Yamamoto, A1
Billups, C; Cabot, MC; Maurer, BJ; Melton, L; Reynolds, CP1
Beckstrøm, KJ; Bettaïeb, A; Laurent, G; Lautier, D; Lehne, G; Maestre, N; Plo, I1
Baccino, FM; Bonelli, G; Codogno, P; De Stefanis, D; Ghidoni, R; Isidoro, C; Reffo, P; Sala, G1
Codogno, P; Dupré, T; Ghidoni, R; Sala, G; Seta, N1
Colligan, PB; Relling, DP; Ren, J1
Abe, A; Hiraoka, M; Shayman, JA1
Hisaki, H; Kubota, M; Masuda, H; Nakagomi, T; Nakane, M; Shimasaki, H; Tamura, A; Ueta, N1
Endo, H; Hanzawa, A; Kanegae, H; Matsumoto, K; Miyazawa, K; Nakabayashi, Y; Shinoda, H; Suda, Y; Suetsugu, M; Takano, A; Takeshita, A; Tanaka, S; Ueyama, Y; Yasui, T1
Chatterjee, S; Kolmakova, A; Pili, R; Rajesh, M; Zang, D1
Ahn, KH; Choi, JM; Jeon, HJ; Ji, JE; Jung, KM; Jung, SY; Kang, MS; Kim, DK; Kim, SK1
Baran, Y; Kartal, M; Sahin, F; Saydam, G1

Reviews

2 review(s) available for 1-phenyl-2-decanoylamino-3-morpholino-1-propanol and sphingosine

ArticleYear
Type C Niemann-Pick disease: use of hydrophobic amines to study defective cholesterol transport.
    Developmental neuroscience, 1991, Volume: 13, Issue:4-5

    Topics: Amines; Androstenes; Animals; Biological Transport; Cells, Cultured; Cholesterol; Cholesterol Esters; Disease Models, Animal; Fibroblasts; Filipin; Humans; Imipramine; Lysosomes; Mice; Morpholines; Niemann-Pick Diseases; Sphingosine; Structure-Activity Relationship

1991
A turn in the road: How studies on the pharmacology of glucosylceramide synthase inhibitors led to the identification of a lysosomal phospholipase A2 with ceramide transacylase activity.
    Glycoconjugate journal, 2004, Volume: 20, Issue:1

    Topics: Acylation; Acyltransferases; Animals; Cattle; Ceramides; DNA, Complementary; Enzyme Inhibitors; Glucosyltransferases; Humans; Lysosomes; Mice; Molecular Structure; Morpholines; Phospholipases A; Phospholipases A2; Signal Transduction; Sphingosine

2004

Other Studies

18 other study(ies) available for 1-phenyl-2-decanoylamino-3-morpholino-1-propanol and sphingosine

ArticleYear
A ceramide analogue inhibits T cell proliferative response through inhibition of glycosphingolipid synthesis and enhancement of N,N-dimethylsphingosine synthesis.
    Biochemistry, 1990, Jul-03, Volume: 29, Issue:26

    Topics: Animals; Cell Division; Ceramides; DNA Replication; Gangliosides; Glycosphingolipids; Interleukin-2; Lymphocyte Activation; Mice; Mice, Inbred C3H; Morpholines; Phytohemagglutinins; Protein-Tyrosine Kinases; Receptors, Interleukin-2; Signal Transduction; Sphingosine; Stereoisomerism; T-Lymphocytes, Cytotoxic

1990
Inhibitors of cerebroside metabolism.
    Methods in enzymology, 1981, Volume: 72

    Topics: Animals; Cerebrosides; Galactosylceramidase; Glucosylceramidase; Glucosyltransferases; Indicators and Reagents; Inositol; Morpholines; Propiophenones; Propylene Glycols; Sphingosine

1981
The synthetic pathway for glucosylsphingosine in cultured fibroblasts.
    Journal of biochemistry, 1994, Volume: 116, Issue:3

    Topics: Acylation; beta-Glucosidase; Cells, Cultured; Cerebrosides; Fibroblasts; Glucosylceramides; Glucosyltransferases; Glycosylation; Humans; Inositol; Morpholines; Psychosine; Sphingosine

1994
Induction of ganglioside biosynthesis and neurite outgrowth of primary cultured neurons by L-threo-1-phenyl-2-decanoylamino-3-morpholino-1-propanol.
    Journal of neurochemistry, 1996, Volume: 67, Issue:5

    Topics: Animals; Carbon Radioisotopes; Cells, Cultured; Ceramides; Embryo, Mammalian; Enzyme Inhibitors; Female; Galactose; Gangliosides; Glycosphingolipids; Humans; Kinetics; Morpholines; Neurites; Neurons; Pregnancy; Radioisotope Dilution Technique; Rats; Rats, Wistar; Serine; Sphingomyelins; Sphingosine; Stereoisomerism; Tritium

1996
Glucosylceramide synthase inhibitor inhibits the action of nerve growth factor in PC12 cells.
    The Journal of biological chemistry, 1998, Oct-02, Volume: 273, Issue:40

    Topics: Animals; Cell Differentiation; Drosophila Proteins; Enzyme Activation; Enzyme Inhibitors; ErbB Receptors; Gangliosides; Glucosyltransferases; Glycosphingolipids; Insect Proteins; Microscopy, Fluorescence; Microscopy, Phase-Contrast; Morpholines; Nerve Growth Factors; Neurons; PC12 Cells; Phosphatidylinositol 3-Kinases; Phosphorylation; Rats; Signal Transduction; Sphingosine

1998
Effects of endoglycoceramidase or D-threo-1-phenyl-2-decanoylamino-3-morpholino-1-propanol on glucose uptake, glycolysis, and mitochondrial respiration in HL60 cells.
    Archives of biochemistry and biophysics, 1998, Nov-01, Volume: 359, Issue:1

    Topics: Cell Membrane Permeability; Cell Respiration; Glucose; Glycolysis; Glycoside Hydrolases; HL-60 Cells; Humans; Intracellular Fluid; Mitochondria; Morpholines; Oxidation-Reduction; Sphingosine

1998
Macrophage TNF mRNA expression induced by LPS is regulated by sphingomyelin metabolites.
    Shock (Augusta, Ga.), 1999, Volume: 11, Issue:6

    Topics: Animals; Ceramides; Endocannabinoids; Enzyme Inhibitors; Ethanolamines; Lipopolysaccharides; Macrophages, Alveolar; Male; Morpholines; Oleic Acids; Rabbits; RNA, Messenger; Sphingomyelins; Sphingosine; Tumor Necrosis Factor-alpha

1999
Implication of sphingolipid metabolism in the stability of the Golgi apparatus.
    Journal of cell science, 2000, Volume: 113 ( Pt 18)

    Topics: Animals; Brefeldin A; Cattle; Cell Line; Ceramides; Coat Protein Complex I; Endocannabinoids; Endosomes; Enzyme Inhibitors; Ethanolamines; Golgi Apparatus; Masoprocol; Microscopy, Electron; Morpholines; Nocodazole; Oleic Acids; Sphingolipids; Sphingomyelin Phosphodiesterase; Sphingosine; trans-Golgi Network

2000
Synergistic cytotoxicity in solid tumor cell lines between N-(4-hydroxyphenyl)retinamide and modulators of ceramide metabolism.
    Journal of the National Cancer Institute, 2000, Dec-06, Volume: 92, Issue:23

    Topics: Antineoplastic Agents; Antineoplastic Agents, Hormonal; Apoptosis; Ceramides; Drug Synergism; Enzyme Inhibitors; Estrogen Receptor Modulators; Fenretinide; Glucosyltransferases; Humans; Morpholines; Necrosis; Neoplasms; Protein Kinase C; Sphingosine; Tamoxifen; Tumor Cells, Cultured; Tumor Suppressor Protein p53

2000
Influence of ceramide metabolism on P-glycoprotein function in immature acute myeloid leukemia KG1a cells.
    Molecular pharmacology, 2002, Volume: 62, Issue:2

    Topics: Acute Disease; Antigens, CD; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Ceramides; Daunorubicin; Drug Interactions; Gangliosides; Glucosylceramides; Humans; Lactosylceramides; Leukemia, Myeloid; Morpholines; Phosphorylation; Sphingosine; Tumor Cells, Cultured; Vincristine

2002
Increase in ceramide level alters the lysosomal targeting of cathepsin D prior to onset of apoptosis in HT-29 colon cancer cells.
    Biological chemistry, 2002, Volume: 383, Issue:6

    Topics: Amide Synthases; Apoptosis; Caspase Inhibitors; Caspases; Cathepsin D; Ceramides; Cytochrome c Group; DNA Fragmentation; Enzyme Inhibitors; Flow Cytometry; HT29 Cells; Humans; Immunoblotting; Lysosomes; Mitochondria; Morpholines; Nucleosomes; Sphingosine

2002
Increased biosynthesis of glycosphingolipids in congenital disorder of glycosylation Ia (CDG-Ia) fibroblasts.
    Pediatric research, 2002, Volume: 52, Issue:5

    Topics: Animals; Antigens, CD; Carbohydrate Metabolism, Inborn Errors; Child; Child, Preschool; CHO Cells; Cricetinae; Cricetulus; Enzyme Inhibitors; Female; Fibroblasts; Glucosyltransferases; Glycoproteins; Glycosphingolipids; Glycosylation; Humans; Lactosylceramides; Male; Morpholines; Phosphotransferases (Phosphomutases); Protein Processing, Post-Translational; Sphingosine

2002
Ceramide attenuates high glucose-induced cardiac contractile abnormalities in cultured adult rat ventricular myocytes.
    Cellular and molecular biology (Noisy-le-Grand, France), 2002, Volume: 48 Online Pub

    Topics: Animals; Calcium; Calcium Signaling; Cells, Cultured; Enzyme Inhibitors; Glucose; Heart Ventricles; Male; Morpholines; Muscle Cells; Myocardial Contraction; Platelet Aggregation Inhibitors; Rats; Rats, Sprague-Dawley; Sphingosine

2002
In vivo influence of ceramide accumulation induced by treatment with a glucosylceramide synthase inhibitor on ischemic neuronal cell death.
    Brain research, 2004, Aug-20, Volume: 1018, Issue:1

    Topics: Animals; Brain Ischemia; Cell Death; Ceramides; Disease Models, Animal; Enzyme Inhibitors; Gerbillinae; Glucosylceramides; Glucosyltransferases; Hippocampus; Male; Morpholines; Nerve Degeneration; Sphingosine

2004
Sphingosine 1-phosphate acts as a signal molecule in ceramide signal transduction of TNF-alpha-induced activator protein-1 in osteoblastic cell line MC3T3-E1 cells.
    Journal of oral science, 2005, Volume: 47, Issue:1

    Topics: 3T3 Cells; Animals; Blotting, Northern; Ceramides; Chemokine CCL2; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Gene Expression; Genes, fos; Genes, jun; Lysophospholipids; Mice; Mice, Inbred C57BL; Morpholines; Osteoblasts; Propanolamines; Pyrrolidines; Recombinant Proteins; Second Messenger Systems; Sphingomyelin Phosphodiesterase; Sphingosine; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Tumor Necrosis Factor-alpha

2005
VEGF recruits lactosylceramide to induce endothelial cell adhesion molecule expression and angiogenesis in vitro and in vivo.
    Glycoconjugate journal, 2009, Volume: 26, Issue:5

    Topics: Animals; Antigens, CD; Blotting, Western; Cell Line; Cell Line, Tumor; Chromones; Endothelial Cells; Female; Fibroblast Growth Factor 2; Galactosyltransferases; Glucosyltransferases; Humans; Lactosylceramides; Mice; Mice, Nude; Morpholines; Neovascularization, Physiologic; Phosphoinositide-3 Kinase Inhibitors; Phosphotransferases (Alcohol Group Acceptor); Platelet Endothelial Cell Adhesion Molecule-1; Receptors, Lysosphingolipid; Sphingosine; Suramin; Vascular Endothelial Growth Factor A

2009
Hypoxia-induced neuronal apoptosis is mediated by de novo synthesis of ceramide through activation of serine palmitoyltransferase.
    Cellular signalling, 2010, Volume: 22, Issue:4

    Topics: Apoptosis; Cell Hypoxia; Cell Line, Tumor; Ceramides; Endocannabinoids; Enzyme Inhibitors; Ethanolamines; Glucosylceramides; Glucosyltransferases; Humans; Morpholines; Neurons; Oleic Acids; Serine C-Palmitoyltransferase; Sphingosine

2010
Resveratrol triggers apoptosis through regulating ceramide metabolizing genes in human K562 chronic myeloid leukemia cells.
    Nutrition and cancer, 2011, Volume: 63, Issue:4

    Topics: Apoptosis; Ceramides; Down-Regulation; Glucosylceramides; Glucosyltransferases; Humans; K562 Cells; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Lysophospholipids; Morpholines; Phosphotransferases (Alcohol Group Acceptor); Resveratrol; RNA, Neoplasm; Sphingosine; Stilbenes; Up-Regulation

2011