1-palmitoyl-2-oleoylphosphatidylcholine and dithiane

1-palmitoyl-2-oleoylphosphatidylcholine has been researched along with dithiane* in 1 studies

Other Studies

1 other study(ies) available for 1-palmitoyl-2-oleoylphosphatidylcholine and dithiane

ArticleYear
Liposomes from novel photolabile phospholipids: light-induced unloading of small molecules as monitored by PFG NMR.
    Journal of the American Chemical Society, 2002, May-22, Volume: 124, Issue:20

    A molecular dithiane-based approach to synthesis of novel photolabile phospholipids is developed. These lipids are used in formulations with egg-POPC and cholesterol to prepare light-sensitive liposomes. Irradiation of such liposomes in PBS buffer (medium pressure mercury lamp, Pyrex filter, lambda > 300 nm) significantly increases the bilayer permeability and accelerates the release of entrapped small organic molecules by an order of magnitude. A simple assay, based on (1)H or (19)F PFG NMR measurements of diffusion coefficients, is developed to monitor light-induced unloading of the probe molecules.

    Topics: Cholesterol; Light; Liposomes; Nuclear Magnetic Resonance, Biomolecular; Phosphatidylcholines; Phospholipids; Photochemistry; Pyridines; Quinolizines; Sulfur Compounds

2002