Page last updated: 2024-09-03

1-o-(2-(2,3-dimethylphenyl)aminobenzoyl)glucopyranuronic acid and diclofenac

1-o-(2-(2,3-dimethylphenyl)aminobenzoyl)glucopyranuronic acid has been researched along with diclofenac in 2 studies

Compound Research Comparison

Studies
(1-o-(2-(2,3-dimethylphenyl)aminobenzoyl)glucopyranuronic acid)
Trials
(1-o-(2-(2,3-dimethylphenyl)aminobenzoyl)glucopyranuronic acid)
Recent Studies (post-2010)
(1-o-(2-(2,3-dimethylphenyl)aminobenzoyl)glucopyranuronic acid)
Studies
(diclofenac)
Trials
(diclofenac)
Recent Studies (post-2010) (diclofenac)
6038,8741,8743,616

Protein Interaction Comparison

ProteinTaxonomy1-o-(2-(2,3-dimethylphenyl)aminobenzoyl)glucopyranuronic acid (IC50)diclofenac (IC50)
Aldo-keto reductase family 1 member B10Homo sapiens (human)1.9
Prostaglandin G/H synthase 1 Bos taurus (cattle)0.003
Prostaglandin G/H synthase 1Ovis aries (sheep)1.3376
Interleukin-8Homo sapiens (human)0.008
Prostaglandin G/H synthase 1Homo sapiens (human)0.0415
Sodium- and chloride-dependent GABA transporter 1Rattus norvegicus (Norway rat)0.5
C-X-C chemokine receptor type 1Homo sapiens (human)0.012
Sodium- and chloride-dependent GABA transporter 2Rattus norvegicus (Norway rat)0.5
Sodium- and chloride-dependent GABA transporter 3Rattus norvegicus (Norway rat)0.5
Prostaglandin G/H synthase 2Homo sapiens (human)0.4165
Prostaglandin G/H synthase 2 Rattus norvegicus (Norway rat)0.5
Sodium- and chloride-dependent betaine transporterRattus norvegicus (Norway rat)0.5
Prostaglandin G/H synthase 2Ovis aries (sheep)1.6867
Prostaglandin G/H synthase 2Mus musculus (house mouse)0.0502
Solute carrier family 22 member 6Homo sapiens (human)4
Prostaglandin G/H synthase 1 Rattus norvegicus (Norway rat)0.5
P2Y purinoceptor 12Rattus norvegicus (Norway rat)0.02

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Grillo, MP; Tadano Lohr, M; Wait, JC1
Obach, RS1

Other Studies

2 other study(ies) available for 1-o-(2-(2,3-dimethylphenyl)aminobenzoyl)glucopyranuronic acid and diclofenac

ArticleYear
Metabolic activation of mefenamic acid leading to mefenamyl-S-acyl-glutathione adduct formation in vitro and in vivo in rat.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:8

    Topics: Animals; Biotransformation; Chromatography, Liquid; Glutathione; Hepatocytes; Humans; In Vitro Techniques; Mefenamic Acid; Rats; Tandem Mass Spectrometry

2012
Glycerolysis of acyl glucuronides as an artifact of in vitro drug metabolism incubations.
    Drug metabolism and disposition: the biological fate of chemicals, 2009, Volume: 37, Issue:8

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Artifacts; Biological Assay; Biotransformation; Carbon Radioisotopes; Chromatography, High Pressure Liquid; Diclofenac; Glucuronates; Glucuronides; Glycerol; Humans; In Vitro Techniques; Mass Spectrometry; Mefenamic Acid; Microsomes, Liver; Naproxen; Propionates; Tolmetin; Uridine Diphosphate Glucuronic Acid

2009