Page last updated: 2024-08-22

1-nitropyrene and 1,8-dinitropyrene

1-nitropyrene has been researched along with 1,8-dinitropyrene in 30 studies

Research

Studies (30)

TimeframeStudies, this research(%)All Research%
pre-199015 (50.00)18.7374
1990's12 (40.00)18.2507
2000's3 (10.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Debnath, AK; Debnath, G; Hansch, C; Lopez de Compadre, RL; Shusterman, AJ1
Imaida, K; King, CM; Lee, MS; Wang, CY1
Doskocil, G; Ghayourmanesh, S; Heisig, V; Hsieh, LL; Jeffrey, AM; Santella, RM; Wong, D1
Hayakawa, K; Imaizumi, N; Miyazaki, M; Suzuki, Y1
Beland, FA; Djuríc, Z; Fifer, EK1
Ishidate, M; Nohmi, T; Watanabe, M1
King, CM1
Beland, FA; Djurić, Z; Heflich, RH; Potter, DW1
Anders, M; Biaglow, MC; Holloway, MP; Howard, PC; McCoy, EC; Rosenkranz, HS1
Aune, T; Deilhaug, T; Haugen, A1
Beland, FA; Cerniglia, CE; Djuric, Z; Fifer, EK; Heflich, RH1
Imaida, K; King, CM; Lee, MS; Tay, LK; Wang, CY1
Adachi, S; Katayama, H; Matsushita, H; Odagiri, Y; Takemoto, K1
Anders, M; McCoy, EC; Mermelstein, R; Rosenkranz, HS1
Beland, FA; Djuric, Z; Fifer, EK; Heflich, RH1
Hasegawa, H; Kato, T; Negishi, C; Ohgaki, H; Sato, S; Sugimura, T1
Dutcher, JS; Li, AP1
Nesnow, S; Slaga, TJ; Triplett, LL1
Katoh, Y; Sugimura, T; Takayama, S; Tanaka, M; Terada, M1
Hayakawa, K; Kawaguchi, Y; Miyazaki, M; Murahashi, T1
Katoh, Y; Maekawa, M; Sano, Y1
Barale, R; Barrai, I; Glussich, I; Micheletti, R; Sbrana, C; Scapoli, C1
Bertoli, C; Carere, A; Conti, L; Crebelli, R; Crochi, B; Del Giacomo, N1
Nohmi, T; Sofuni, T; Watanabe, M1
Matsui, K; Matsui, M; Nohmi, T; Sofuni, T; Watanabe, M; Yamada, M1
Eddy, EP; Howard, PC; McCoy, EC; Rosenkranz, HS; Silvers, KJ1
Gonzáez de Mejía, E; Loarca-Piña, G; Quintanar-Hernández, A1
Guengerich, FP; Hatanaka, N; Hayakawa, K; Kizu, R; Nakajima, M; Shimada, N; Yamazaki, H; Yokoi, T1
Basu, AK; Broyde, S; Hilario, P; Hingerty, BE; Yan, S1
Arlt, VM; Asare, N; Gorria, M; Holme, JA; Lagadic-Gossmann, D; Landvik, NE; Solhaug, A1

Reviews

1 review(s) available for 1-nitropyrene and 1,8-dinitropyrene

ArticleYear
Structure-activity relationship of mutagenic aromatic and heteroaromatic nitro compounds. Correlation with molecular orbital energies and hydrophobicity.
    Journal of medicinal chemistry, 1991, Volume: 34, Issue:2

    Topics: Animals; Chemical Phenomena; Chemistry; Mutagenicity Tests; Mutagens; Nitro Compounds; Structure-Activity Relationship

1991

Other Studies

29 other study(ies) available for 1-nitropyrene and 1,8-dinitropyrene

ArticleYear
Carcinogenicity of dinitropyrenes in the weanling female CD rat.
    Carcinogenesis, 1991, Volume: 12, Issue:7

    Topics: Adenocarcinoma; Adenofibroma; Animals; Carcinogens; Female; Histiocytoma, Benign Fibrous; Leukemia, Experimental; Mammary Neoplasms, Experimental; Pyrenes; Rats; Rats, Inbred Strains

1991
Metabolic activation of nitropyrenes and diesel particulate extracts.
    Research report (Health Effects Institute), 1990, Issue:34

    Topics: Animals; Cattle; DNA; DNA Damage; Female; Fuel Oils; Humans; Male; Mice; Mutagenicity Tests; Mutagens; Nitro Compounds; Pyrenes; Rabbits; Rats; Vehicle Emissions

1990
Determination of nitrated pyrenes and their derivatives by high performance liquid chromatography with chemiluminescence detection after online electrochemical reduction.
    Biomedical chromatography : BMC, 1990, Volume: 4, Issue:3

    Topics: Chromatography, High Pressure Liquid; Electrochemistry; Luminescent Measurements; Mutagens; Nitrate Reductase; Nitrate Reductases; Polycyclic Compounds; Pyrenes

1990
Acetyl coenzyme A-dependent binding of carcinogenic and mutagenic dinitropyrenes to DNA.
    Carcinogenesis, 1985, Volume: 6, Issue:6

    Topics: Acetyl Coenzyme A; Animals; Carcinogens, Environmental; Cytosol; DNA; Dogs; In Vitro Techniques; Liver; Male; Mutagens; Pyrenes; Rats; Rats, Inbred F344; Vehicle Emissions

1985
New tester strains of Salmonella typhimurium highly sensitive to mutagenic nitroarenes.
    Biochemical and biophysical research communications, 1987, Sep-30, Volume: 147, Issue:3

    Topics: 4-Nitroquinoline-1-oxide; Acetyltransferases; Cloning, Molecular; Heterocyclic Compounds; Mutagenicity Tests; Mutagens; Nitro Compounds; Nitrofurazone; Nitroquinolines; Nitroreductases; Oxidoreductases; Polycyclic Compounds; Pyrenes; Salmonella typhimurium

1987
Metabolism and biological effects of nitropyrene and related compounds.
    Research report (Health Effects Institute), 1988, Issue:16

    Topics: Animals; Carcinogenicity Tests; Female; Histiocytoma, Benign Fibrous; Leukemia; Mammary Neoplasms, Animal; Pyrenes; Rats

1988
Aerobic and anaerobic reduction of nitrated pyrenes in vitro.
    Chemico-biological interactions, 1986, Oct-01, Volume: 59, Issue:3

    Topics: Animals; Cytochrome c Group; Cytosol; Humans; Male; Microsomes, Liver; NADP; Oxidation-Reduction; Pyrenes; Rats; Salmonella typhimurium

1986
Photochemical instability of 1-nitropyrene, 3-nitrofluoranthene, 1,8-dinitropyrene and their parent polycyclic aromatic hydrocarbons.
    Mutation research, 1987, Volume: 187, Issue:4

    Topics: Dimethyl Sulfoxide; Fluorenes; Half-Life; Light; Photochemistry; Pyrenes; Silicon Dioxide

1987
Nitropyrene-induced DNA repair in Clara cells and alveolar type-II cells isolated from rabbit lung.
    Mutation research, 1986, Volume: 175, Issue:4

    Topics: Animals; DNA Repair; Dose-Response Relationship, Drug; Lung; Male; Pyrenes; Rabbits

1986
Metabolism of dinitropyrenes to DNA-binding derivatives in vitro and in vivo.
    Developments in toxicology and environmental science, 1986, Volume: 13

    Topics: Animals; Bacteria; DNA; DNA Damage; In Vitro Techniques; Intestines; Liver; Male; Mammary Glands, Animal; Mutagens; Oxidation-Reduction; Pyrenes; Rats; Rats, Inbred Strains

1986
Mechanisms of tumor induction by dinitropyrenes in the female CD rat.
    Developments in toxicology and environmental science, 1986, Volume: 13

    Topics: Animals; Cells, Cultured; Female; Injections, Intraperitoneal; Injections, Subcutaneous; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Mutagens; Neoplasms, Experimental; Oxidation-Reduction; Pyrenes; Rats; Rats, Inbred Strains; Structure-Activity Relationship

1986
Carcinogenic effects of a mixture of nitropyrenes in F344 rats following its repeated oral administrations.
    Developments in toxicology and environmental science, 1986, Volume: 13

    Topics: Administration, Oral; Animals; Body Weight; Clitoris; Female; Leukemia, Experimental; Mammary Neoplasms, Experimental; Mutagens; Neoplasms, Experimental; Organ Size; Pyrenes; Rats; Rats, Inbred F344; Vulvar Neoplasms

1986
Mutagenicity of nitropyrenes for Escherichia coli: requirement for increased cellular permeability.
    Mutation research, 1985, Volume: 142, Issue:4

    Topics: Cell Membrane Permeability; Escherichia coli; Mutagenicity Tests; Mutagens; Plasmids; Pyrenes

1985
DNA adduct formation and mutation induction by nitropyrenes in Salmonella and Chinese hamster ovary cells: relationships with nitroreduction and acetylation.
    Environmental health perspectives, 1985, Volume: 62

    Topics: Animals; Cell Line; Cricetinae; Cricetulus; DNA; DNA, Bacterial; Female; Genes; Hypoxanthine Phosphoribosyltransferase; Mutagenicity Tests; Mutagens; Mutation; Ovary; Pyrenes; Salmonella typhimurium; Structure-Activity Relationship

1985
Absence of carcinogenicity of 1-nitropyrene, correction of previous results, and new demonstration of carcinogenicity of 1,6-dinitropyrene in rats.
    Cancer letters, 1985, Volume: 25, Issue:3

    Topics: Animals; Dose-Response Relationship, Drug; Male; Mutagens; Neoplasms, Experimental; Pyrenes; Rats; Rats, Inbred F344; Time Factors

1985
Mutagenicity of mono-, di- and tri-nitropyrenes in Chinese hamster ovary cells.
    Mutation research, 1983, Volume: 119, Issue:3

    Topics: Animals; Cricetinae; Cricetulus; Female; Mutagenicity Tests; Mutagens; Ovary; Pyrenes

1983
Tumor initiating activities of 1-nitropyrene and its nitrated products in SENCAR mice.
    Cancer letters, 1984, Volume: 23, Issue:1

    Topics: Administration, Topical; Animals; Female; Injections, Intraperitoneal; Male; Mice; Mutagens; Papilloma; Pyrenes; Skin Neoplasms

1984
Mutagenicity of nitropyrenes in Chinese hamster V79 cells.
    Gan, 1983, Volume: 74, Issue:3

    Topics: Animals; Biotransformation; Cricetinae; Cricetulus; Mesocricetus; Mutagens; Ouabain; Pyrenes

1983
Distributions of nitropyrenes and mutagenicity in airborne particulates collected with an Andersen sampler.
    Mutation research, 1995, Volume: 348, Issue:2

    Topics: Air Pollution; Chromatography, High Pressure Liquid; Mutagenicity Tests; Mutagens; Pyrenes; Salmonella typhimurium

1995
Mutagenic effects of nitropyrenes in a soybean test system.
    Mutation research, 1994, Volume: 320, Issue:1-2

    Topics: Chi-Square Distribution; Chromatography, High Pressure Liquid; Chromosome Deletion; Drug Synergism; Glycine max; Isomerism; Liver Extracts; Microsomes, Liver; Mutagenicity Tests; Mutagens; Point Mutation; Pyrenes; Structure-Activity Relationship

1994
N-acetylcysteine inhibits diesel extract mutagenicity in the Ames test and SCE induction in human lymphocytes.
    Basic life sciences, 1993, Volume: 61

    Topics: Acetylcysteine; Antimutagenic Agents; Fossil Fuels; Humans; Lymphocytes; Mutagenicity Tests; Mutagens; Pyrenes; Salmonella typhimurium; Sister Chromatid Exchange; Vehicle Emissions

1993
The effect of fuel composition on the mutagenicity of diesel engine exhaust.
    Mutation research, 1995, Volume: 346, Issue:3

    Topics: Mutagenicity Tests; Mutagens; Petroleum; Polycyclic Compounds; Pyrenes; Salmonella typhi; Vehicle Emissions

1995
Comparison of the sensitivity of Salmonella typhimurium strains YG1024 and YG1012 for detecting the mutagenicity of aromatic amines and nitroarenes.
    Mutation research, 1993, Volume: 301, Issue:1

    Topics: 1-Naphthylamine; 4-Nitroquinoline-1-oxide; Acetyltransferases; Acyltransferases; Amines; Anthracenes; Cloning, Molecular; Environmental Pollutants; Frameshift Mutation; Hydroxyacetylaminofluorene; Hydroxylamines; Imidazoles; Microbial Sensitivity Tests; Mutagenicity Tests; Mutagens; Naphthalenes; Nitro Compounds; Plasmids; Pyrenes; Salmonella typhimurium; Species Specificity

1993
Involvement of umuDCST genes in nitropyrene-induced -CG frameshift mutagenesis at the repetitive CG sequence in the hisD3052 allele of Salmonella typhimurium.
    Molecular & general genetics : MGG, 1995, Apr-10, Volume: 247, Issue:1

    Topics: Alcohol Oxidoreductases; Bacterial Proteins; Base Sequence; DNA Mutational Analysis; DNA, Bacterial; Fluorenes; Frameshift Mutation; Gene Deletion; Genes, Bacterial; Histidine; Hydroxyacetylaminofluorene; Imidazoles; Molecular Sequence Data; Mutagens; Operon; Plasmids; Pyrenes; Repetitive Sequences, Nucleic Acid; Salmonella typhimurium; Suppression, Genetic

1995
Pathways for the mutagenesis of 1-nitropyrene and dinitropyrenes in the human hepatoma cell line HepG2.
    Environmental health perspectives, 1994, Volume: 102 Suppl 6

    Topics: Biotransformation; Carcinogens; Carcinoma, Hepatocellular; Humans; Liver Neoplasms; Mutagenesis; Mutagens; Pyrenes; Tumor Cells, Cultured

1994
Antimutagenic activity of carotenoids in green peppers against some nitroarenes.
    Mutation research, 1998, Aug-07, Volume: 416, Issue:1-2

    Topics: Antimutagenic Agents; beta Carotene; Capsicum; Carotenoids; Dose-Response Relationship, Drug; Mutagenicity Tests; Mutagens; Mutation; Plants, Medicinal; Pyrenes; Salmonella typhimurium

1998
Bioactivation of diesel exhaust particle extracts and their major nitrated polycyclic aromatic hydrocarbon components, 1-nitropyrene and dinitropyrenes, by human cytochromes P450 1A1, 1A2, and 1B1.
    Mutation research, 2000, Dec-20, Volume: 472, Issue:1-2

    Topics: Aryl Hydrocarbon Hydroxylases; Biotransformation; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP1B1; Cytochrome P-450 Enzyme System; Escherichia coli; Humans; Mutagenicity Tests; Mutagens; NADPH-Ferrihemoprotein Reductase; Pyrenes; Recombinant Fusion Proteins; Salmonella typhimurium; Structure-Activity Relationship; Vehicle Emissions

2000
Comparative mutagenesis of the C8-guanine adducts of 1-nitropyrene and 1,6- and 1,8-dinitropyrene in a CpG repeat sequence. A slipped frameshift intermediate model for dinucleotide deletion.
    The Journal of biological chemistry, 2002, Nov-22, Volume: 277, Issue:47

    Topics: CpG Islands; DNA Adducts; DNA Repair; DNA, Single-Stranded; Escherichia coli; Genetic Vectors; Hydrogen Bonding; Models, Molecular; Molecular Structure; Mutagenesis; Mutagens; Nucleic Acid Conformation; Phenotype; Pyrenes

2002
Effects of nitrated-polycyclic aromatic hydrocarbons and diesel exhaust particle extracts on cell signalling related to apoptosis: possible implications for their mutagenic and carcinogenic effects.
    Toxicology, 2007, Mar-07, Volume: 231, Issue:2-3

    Topics: Animals; Apoptosis; Carcinogens, Environmental; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Nucleus; Cell Survival; DNA Adducts; DNA Damage; Dose-Response Relationship, Drug; Hepatocytes; Lipid Peroxidation; Mice; Mutagens; Phosphorylation; Pyrenes; Quantitative Structure-Activity Relationship; Signal Transduction; Tumor Suppressor Protein p53; Vehicle Emissions

2007