Compounds > 1-n-me-tyr(1)-7-n-me-arg-8-n-et-leunh2-dynorphin (1-8)

Page last updated: 2024-09-03

1-n-me-tyr(1)-7-n-me-arg-8-n-et-leunh2-dynorphin (1-8) and norbinaltorphimine

1-n-me-tyr(1)-7-n-me-arg-8-n-et-leunh2-dynorphin (1-8) has been researched along with norbinaltorphimine in 4 studies

Compound Research Comparison

Studies (1-n-me-tyr(1)-7-n-me-arg-8-n-et-leunh2-dynorphin (1-8))	Trials (1-n-me-tyr(1)-7-n-me-arg-8-n-et-leunh2-dynorphin (1-8))	Recent Studies (post-2010) (1-n-me-tyr(1)-7-n-me-arg-8-n-et-leunh2-dynorphin (1-8))	Studies (norbinaltorphimine)	Trials (norbinaltorphimine)	Recent Studies (post-2010) (norbinaltorphimine)
35	2	0	918	0	205

Protein Interaction Comparison

Protein	Taxonomy	1-n-me-tyr(1)-7-n-me-arg-8-n-et-leunh2-dynorphin (1-8) (IC50)	norbinaltorphimine (IC50)
Delta-type opioid receptor	Mus musculus (house mouse)		0.0104
Kappa-type opioid receptor	Mus musculus (house mouse)		0.0029
Mu-type opioid receptor	Homo sapiens (human)		0.212
Delta-type opioid receptor	Homo sapiens (human)		0.024
Kappa-type opioid receptor	Homo sapiens (human)		0.0036

Research

Studies (4)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	4 (100.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Akil, H; Goldstein, A; Mansour, A; Meng, F; Thompson, RC; Watson, SJ; Xie, GX	1
Furuya, Y; Kaneko, T; Nakazawa, T; Yamatsu, K	1
Funada, M; Misawa, M; Nagase, H; Narita, M; Suzuki, T	1
Misawa, M; Nagase, H; Suzuki, T; Tsuda, M	1

Other Studies

4 other study(ies) available for 1-n-me-tyr(1)-7-n-me-arg-8-n-et-leunh2-dynorphin (1-8) and norbinaltorphimine

Article	Year
Cloning and pharmacological characterization of a rat kappa opioid receptor. Proceedings of the National Academy of Sciences of the United States of America, 1993, Nov-01, Volume: 90, Issue:21 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Amino Acid Sequence; Analgesics; Animals; Benzeneacetamides; Cell Line; Cell Membrane; Cloning, Molecular; Corpus Striatum; Cyclic AMP; DNA Primers; DNA, Complementary; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Gene Library; In Situ Hybridization; Inositol 1,4,5-Trisphosphate; Kinetics; Ligands; Molecular Sequence Data; Pyrrolidines; Rats; Receptors, Opioid, kappa; Restriction Mapping; RNA, Messenger; Transfection	1993
Spinal kappa receptor-mediated analgesia of E-2078, a systemically active dynorphin analog, in mice. The Journal of pharmacology and experimental therapeutics, 1991, Volume: 256, Issue:1 Topics: Analgesics; Animals; Dose-Response Relationship, Drug; Dynorphins; Injections, Intraventricular; Injections, Spinal; Male; Mice; Mice, Inbred Strains; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Peptide Fragments; Receptors, Opioid, kappa; Receptors, Opioid, mu; Spinal Cord	1991
Blockade of morphine reward through the activation of kappa-opioid receptors in mice. Neuropharmacology, 1993, Volume: 32, Issue:12 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; 3,4-Dihydroxyphenylacetic Acid; Analgesics; Animals; Apomorphine; Conditioning, Operant; Dopamine; Dynorphins; Homovanillic Acid; Injections, Subcutaneous; Limbic System; Male; Mice; Mice, Inbred Strains; Morphine; Motivation; Naltrexone; Peptide Fragments; Prosencephalon; Pyrrolidines; Receptors, Opioid, kappa; Reward	1993
Involvement of the opioid system in the anxiolytic effect of diazepam in mice. European journal of pharmacology, 1996, Jun-20, Volume: 307, Issue:1 Topics: Analgesics, Non-Narcotic; Animals; Anti-Anxiety Agents; Anticonvulsants; Body Temperature; Conflict, Psychological; Diazepam; Drug Interactions; Dynorphins; Male; Mice; Mice, Inbred Strains; Motor Activity; Naltrexone; Narcotic Antagonists; Peptide Fragments; Receptors, Opioid; Receptors, Opioid, kappa	1996