1-n-me-tyr(1)-7-n-me-arg-8-n-et-leunh2-dynorphin (1-8) has been researched along with naloxone in 4 studies
| Studies (1-n-me-tyr(1)-7-n-me-arg-8-n-et-leunh2-dynorphin (1-8)) | Trials (1-n-me-tyr(1)-7-n-me-arg-8-n-et-leunh2-dynorphin (1-8)) | Recent Studies (post-2010) (1-n-me-tyr(1)-7-n-me-arg-8-n-et-leunh2-dynorphin (1-8)) | Studies (naloxone) | Trials (naloxone) | Recent Studies (post-2010) (naloxone) |
|---|---|---|---|---|---|
| 35 | 2 | 0 | 20,134 | 1,257 | 3,321 |
| Protein | Taxonomy | 1-n-me-tyr(1)-7-n-me-arg-8-n-et-leunh2-dynorphin (1-8) (IC50) | naloxone (IC50) |
|---|---|---|---|
| Cytochrome P450 2D6 | Homo sapiens (human) | 2 | |
| Delta-type opioid receptor | Mus musculus (house mouse) | 0.043 | |
| Delta-type opioid receptor | Rattus norvegicus (Norway rat) | 0.0219 | |
| Mu-type opioid receptor | Rattus norvegicus (Norway rat) | 0.0019 | |
| Kappa-type opioid receptor | Rattus norvegicus (Norway rat) | 0.0019 | |
| Mu-type opioid receptor | Homo sapiens (human) | 0.0397 | |
| Delta-type opioid receptor | Homo sapiens (human) | 0.1896 | |
| Kappa-type opioid receptor | Cavia porcellus (domestic guinea pig) | 0.05 | |
| Kappa-type opioid receptor | Homo sapiens (human) | 0.0795 | |
| Mu-type opioid receptor | Mus musculus (house mouse) | 0.0154 | |
| Mu-type opioid receptor | Cavia porcellus (domestic guinea pig) | 0.0089 | |
| Beta-2 adrenergic receptor | Cavia porcellus (domestic guinea pig) | 0.0055 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Akil, H; Goldstein, A; Mansour, A; Meng, F; Thompson, RC; Watson, SJ; Xie, GX | 1 |
| Furuya, Y; Kaneko, T; Nakazawa, T; Yamatsu, K | 1 |
| Goto, M; Kaneko, T; Nakazawa, T; Tachibana, S; Taki, T; Yamatsu, K; Yoshino, H | 1 |
| Furuya, Y; Kaneko, T; Nakazawa, T; Tachibana, S; Yamatsu, K; Yoshino, H | 1 |
4 other study(ies) available for 1-n-me-tyr(1)-7-n-me-arg-8-n-et-leunh2-dynorphin (1-8) and naloxone
| Article | Year |
|---|---|
Cloning and pharmacological characterization of a rat kappa opioid receptor.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Amino Acid Sequence; Analgesics; Animals; Benzeneacetamides; Cell Line; Cell Membrane; Cloning, Molecular; Corpus Striatum; Cyclic AMP; DNA Primers; DNA, Complementary; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Gene Library; In Situ Hybridization; Inositol 1,4,5-Trisphosphate; Kinetics; Ligands; Molecular Sequence Data; Pyrrolidines; Rats; Receptors, Opioid, kappa; Restriction Mapping; RNA, Messenger; Transfection | 1993 |
Spinal kappa receptor-mediated analgesia of E-2078, a systemically active dynorphin analog, in mice.
Topics: Analgesics; Animals; Dose-Response Relationship, Drug; Dynorphins; Injections, Intraventricular; Injections, Spinal; Male; Mice; Mice, Inbred Strains; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Peptide Fragments; Receptors, Opioid, kappa; Receptors, Opioid, mu; Spinal Cord | 1991 |
Physical dependence liability of dynorphin A analogs in rodents.
Topics: Analgesics; Animals; Dynorphins; Injections, Subcutaneous; Male; Mice; Mice, Inbred Strains; Naloxone; Peptide Fragments; Rats; Rats, Inbred Strains; Substance Withdrawal Syndrome; Substance-Related Disorders | 1991 |
Analgesia produced by E-2078, a systemically active dynorphin analog, in mice.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesia; Analgesics; Animals; Buprenorphine; Drug Interactions; Dynorphins; Male; Mice; Morphine; Naloxone; Peptide Fragments; Pyrrolidines; Receptors, Opioid | 1990 |