1-monooleoyl-rac-glycerol has been researched along with coumarin* in 1 studies
1 other study(ies) available for 1-monooleoyl-rac-glycerol and coumarin
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Photo responsive monoolein cubic phase containing coumarin-Tween 20 conjugates.
Photo-responsive monoolein (MO) cubic phase was developed by incorporating coumarin-Tween 20 conjugate in the cubic phase. 7-chlorocarbonylmethoxycoumarin was obtained from 7-hydroxycoumarin through three-step reactions with the yield of 19.8% and it was conjugated to the head group of Tween 20. The molar ratio of the coumarin derivative/Tween 20 in the conjugate was about 1/1 on ¹H NMR spectrum. The cubic phase was prepared by melting the mixture of MO/conjugate (100/0.88, w/w) and hydrating the molten mixture with 5(6)-carboxyfluorescein (CF) solution. UV irradiation (254 nm and/or 365 nm) for 3 h resulted in 1.27% to 2.69% reduction in the double bond of MO but the cubic phase was stable in terms of its integrity under the UV irradiation. The release of CF from coumarin-Tween 20 conjugate-incorporated cubic phase was somewhat suppressed by being subjected to the UV irradiation. The head groups of coumarin-Tween 20 conjugate will be cross-linked so the diffusion in the water channel will be suppressed. Topics: Anticoagulants; Coumarins; Dimerization; Drug Delivery Systems; Drug Stability; Fluoresceins; Fluorescent Dyes; Glycerides; Hot Temperature; Hymecromone; Kinetics; Magnetic Resonance Spectroscopy; Pharmaceutical Vehicles; Phase Transition; Photochemical Processes; Polysorbates; Solubility; Surface-Active Agents; Ultraviolet Rays; Umbelliferones | 2013 |