Page last updated: 2024-08-25

1-methylxanthine and uracil

1-methylxanthine has been researched along with uracil in 37 studies

Research

Studies (37)

Timeframe	Studies, this research(%)	All Research%
pre-1990	5 (13.51)	18.7374
1990's	16 (43.24)	18.2507
2000's	11 (29.73)	29.6817
2010's	5 (13.51)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Ebihara, A; Hashiguchi, M	1
Iriah, J; Kadar, D; Kalow, W; Qian, L; Tang, BK; Yip, J	1
Eichelbaum, M; Grant, DM; Meyer, UA; Mörike, K	1
Beitins, IZ; Kilbane, AJ; Manis, M; Silbart, LK; Weber, WW	1
Butler, MA; Kadlubar, FF; Lang, NP; Massengill, JP; Talaska, G; Teitel, CH	1
Griener, JC; Morris, ME; Msall, ME	1
Hildebrand, M; Seifert, W	1
Chaleby, K; el-Yazigi, A; Martin, CR	1
Lorenzo, B; Reidenberg, MM	1
Campbell, ME; Kalow, W; Spielberg, SP	1
Bresnick, E; McQuilkin, SH; Nierenberg, DW	1
Cribb, AE; Gillespie, CT; Isbrucker, R; Levatte, T; Renton, KW; Tsui, B	1
Gee, RL; Kloth, MT; Messing, EM; Swaminathan, S	1
Galteau, MM; Gueguen, R; Pontes, ZB; Siest, G; Vincent-Viry, M	1
Bell, DA; Brubaker, LH; Butler, MA; Kadlubar, FF; Lucier, GW; Stephens, EA; Taylor, JA; Wiest, J	1
Arvela, P; Klebovich, I; Pelkonen, O	1
Bechtel, PR; Bechtel, YC; Bonaiti-Pellie, C; Magnette, J; Poisson, N	1
Leyland-Jones, B; Wainer, IW; Wong, P	1
Bernal, ML; Fanlo, A; Juste, JL; Lanuza, J; Mayayo, E; Sáenz, MA; Sinués, B	1
Banerjee, K; Lang, N; Leyland-Jones, B; Massengill, J; Nowell, S; Wong, P	1
Cao, XM; Ling, SS; Lu, JF; Yi, T; Zhuo, HT	1
Cao, XM; Lin, SS; Lu, JF; Yi, T; Zhuo, HT	1
Cui, X; Guo, R; Li, C; Wang, B; Xu, Z	1
Abraham, K; Bauer, S; Brockmöller, J; Geusau, A; Helge, H; Tosun, Y	1
Borlak, J; Cascorbi, I; Erb, K; Fuhr, U; Hermann, R; Illauer, M; Jetter, A; Kinzig-Schippers, M; Smith, G; Sörgel, F; Wolf, H	1
Blaszkewicz, M; Bolt, HM; Dannappel, D; Golka, K; Selinski, S	1
Li, J; Peng, XQ; Xu, JP; Zhang, J	1
Brüning, T; John, A; Rihs, HP; Scherenberg, M; Seidel, A	1
Brøsen, K; Damkier, P; Grandjean, P; Halling, J; Nielsen, F; Petersen, MS; Weihe, P	1
Asprodini, EK; Begas, E; Kouvaras, E; Papakosta, S; Tsakalof, A	1
Fuhr, U; Jetter, A; Kinzig, M; Rodamer, M; Sörgel, F; Tomalik-Scharte, D	1
Ashida, H; Hashimoto, T; Kanazawa, K; Nakabayashi, H; Nishiumi, S	1
Aklillu, E; Carrillo, JA; Djordjevic, N; Fukasawa, T; Gervasini, G; Jankovic, S; Suda, A; Ueda, N	1
Aklillu, E; Bertilsson, L; Carrillo, JA; Djordjevic, N; Karlsson, S; Roh, HK; Ueda, N	1
Fan, XR; Li, XY; Li, YF; Li, YP; Liu, YN; Yang, M; Yao, XC; Yin, YM; Yuan, M; Zhu, JB	1
Ahluwalia, N; Pao, CI; Pfeiffer, CM; Rybak, ME; Sternberg, MR	1
Aklillu, E; Bertilsson, L; Carrillo, JA; Djordjevic, N; Makonnen, E	1

Other Studies

37 other study(ies) available for 1-methylxanthine and uracil

Article	Year
Acetylation polymorphism of caffeine in a Japanese population. Clinical pharmacology and therapeutics, 1992, Volume: 52, Issue:3 Topics: Acetylation; Adult; Caffeine; Humans; Japan; Male; Metabolism; Phenotype; Polymorphism, Genetic; Uracil; Xanthines	1992
Caffeine as a metabolic probe: validation of its use for acetylator phenotyping. Clinical pharmacology and therapeutics, 1991, Volume: 49, Issue:6 Topics: Acetylation; Acetyltransferases; Adult; Caffeine; Humans; Phenotype; Polymorphism, Genetic; Sulfamethazine; Time Factors; Uracil; Uric Acid; Xanthines	1991
Acetylation pharmacogenetics. The slow acetylator phenotype is caused by decreased or absent arylamine N-acetyltransferase in human liver. The Journal of clinical investigation, 1990, Volume: 85, Issue:3 Topics: Acetylation; Acetyltransferases; Adult; Aged; Arylamine N-Acetyltransferase; DNA; Female; Humans; Liver; Male; Middle Aged; Phenotype; Uracil; Xanthines	1990
Human N-acetylation genotype determination with urinary caffeine metabolites. Clinical pharmacology and therapeutics, 1990, Volume: 47, Issue:4 Topics: Acetylation; Caffeine; Chromatography, High Pressure Liquid; Gene Frequency; Genetics, Population; Genotype; Humans; Nitrogen; Pedigree; Phenotype; Theophylline; Time Factors; Uracil; Uric Acid; Xanthines	1990
Determination of carcinogenic arylamine N-oxidation phenotype in humans by analysis of caffeine urinary metabolites. Progress in clinical and biological research, 1990, Volume: 340B Topics: Acetylation; Arylamine N-Acetyltransferase; Biotransformation; Caffeine; Cytochrome P-450 Enzyme System; Disease Susceptibility; Humans; Isoenzymes; Oxidation-Reduction; Phenotype; Theophylline; Uracil; Urinary Bladder Neoplasms; Xanthines	1990
N-acetylator variability in Down's syndrome: characterization with caffeine. Clinical pharmacology and therapeutics, 1989, Volume: 46, Issue:3 Topics: Acetylation; Adolescent; Adult; Caffeine; Child; Chromatography, High Pressure Liquid; Down Syndrome; Female; Humans; Male; Middle Aged; Phenotype; Uracil; Xanthines	1989
Determination of acetylator phenotype in Caucasians with caffeine. European journal of clinical pharmacology, 1989, Volume: 37, Issue:5 Topics: Acetylation; Adolescent; Adult; Aged; Caffeine; Female; Humans; Male; Middle Aged; Phenotype; Sex Factors; Smoking; Uracil; White People; Xanthines	1989
Acetylator phenotypes of Saudi Arabians by a simplified caffeine metabolites test. Journal of clinical pharmacology, 1989, Volume: 29, Issue:3 Topics: Acetylation; Adolescent; Adult; Aged; Child; Chromatography, High Pressure Liquid; Female; Humans; Male; Middle Aged; Phenotype; Saudi Arabia; Uracil; Xanthines	1989
Potential artifacts in the use of caffeine to determine acetylation phenotype. British journal of clinical pharmacology, 1989, Volume: 28, Issue:2 Topics: Acetylation; Caffeine; False Positive Reactions; Humans; Phenotype; Time Factors; Uracil; Xanthines	1989
A urinary metabolite ratio that reflects systemic caffeine clearance. Clinical pharmacology and therapeutics, 1987, Volume: 42, Issue:2 Topics: Adult; Age Factors; Asian People; Caffeine; Child; Child, Preschool; Contraceptives, Oral; Cytochrome P-450 Enzyme System; Female; Humans; Kinetics; Male; Metabolic Clearance Rate; Middle Aged; Smoking; Time Factors; Uracil; Uric Acid; White People; Xanthines	1987
Analysis of within-subject variation of caffeine metabolism when used to determine cytochrome P4501A2 and N-acetyltransferase-2 activities. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 1995, Volume: 4, Issue:2 Topics: Adult; Arylamine N-Acetyltransferase; Caffeine; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP1A2; Cytochrome P-450 Enzyme System; Female; Genetic Variation; Humans; Male; Middle Aged; Oxidoreductases; Phenotype; Spectrophotometry, Ultraviolet; Theophylline; Time Factors; Uracil; Xanthines	1995
Acetylator phenotyping: the urinary caffeine metabolite ratio in slow acetylators correlates with a marker of systemic NAT1 activity. Pharmacogenetics, 1994, Volume: 4, Issue:3 Topics: 4-Aminobenzoic Acid; Acetylation; Adult; Arylamine N-Acetyltransferase; Biomarkers; Caffeine; Female; Humans; Isoenzymes; Kinetics; Leukocytes, Mononuclear; Male; Middle Aged; Phenotype; Substrate Specificity; Uracil; Xanthines	1994
Expression of N-acetyltransferase (NAT) in cultured human uroepithelial cells. Carcinogenesis, 1994, Volume: 15, Issue:12 Topics: Acetylation; Adult; Alleles; Amines; Arylamine N-Acetyltransferase; Biomarkers; Caffeine; Cells, Cultured; Cytochrome P-450 CYP1A2; Cytochrome P-450 Enzyme System; DNA, Complementary; Epithelial Cells; Epithelium; Female; Gene Expression; Genetic Predisposition to Disease; Humans; Male; Microsomes, Liver; Oxidoreductases; Phenotype; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Risk Factors; Uracil; Ureter; Urinary Bladder Neoplasms; Xanthines	1994
Segregation analyses of four urinary caffeine metabolite ratios implicated in the determination of human acetylation phenotypes. Genetic epidemiology, 1994, Volume: 11, Issue:2 Topics: Acetylation; Adolescent; Adult; Alleles; Arylamine N-Acetyltransferase; Caffeine; Child; Chromatography, High Pressure Liquid; Family; Female; Gene Frequency; Genes, Recessive; Humans; Male; Middle Aged; Models, Genetic; Models, Statistical; Phenotype; Polymorphism, Genetic; Theophylline; Uracil; Uric Acid; Xanthines	1994
Genotype/phenotype discordance for human arylamine N-acetyltransferase (NAT2) reveals a new slow-acetylator allele common in African-Americans. Carcinogenesis, 1993, Volume: 14, Issue:8 Topics: Acetylation; Alleles; Amino Acid Sequence; Arylamine N-Acetyltransferase; Base Sequence; Black People; Caffeine; Genotype; Humans; Molecular Sequence Data; Phenotype; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Sequence Homology, Amino Acid; United States; Uracil; Xanthines	1993
HPLC method for rapid determination of acetylator phenotype by measuring urinary caffeine metabolites. Journal of pharmaceutical and biomedical analysis, 1993, Volume: 11, Issue:10 Topics: Caffeine; Chromatography, High Pressure Liquid; Humans; Phenotype; Reproducibility of Results; Uracil; Xanthines	1993
A population and family study of N-acetyltransferase using caffeine urinary metabolites. Clinical pharmacology and therapeutics, 1993, Volume: 54, Issue:2 Topics: Acetylation; Arylamine N-Acetyltransferase; Caffeine; Family; Heterozygote; Humans; Models, Statistical; Time Factors; Uracil; Xanthines	1993
A competitive enzyme linked immunosorbent assay for the determination of N-acetyltransferase (NAT2) phenotypes. Journal of pharmaceutical and biomedical analysis, 1995, Volume: 13, Issue:9 Topics: Animals; Antibody Formation; Antigen-Antibody Complex; Arylamine N-Acetyltransferase; Binding, Competitive; Cross Reactions; Enzyme-Linked Immunosorbent Assay; Female; Humans; Immunoglobulin G; Magnetic Resonance Spectroscopy; Phenotype; Rabbits; Uracil; Xanthines	1995
Five caffeine metabolite ratios to measure tobacco-induced CYP1A2 activity and their relationships with urinary mutagenicity and urine flow. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 1999, Volume: 8, Issue:2 Topics: Adolescent; Adult; Caffeine; Central Nervous System Stimulants; Cytochrome P-450 CYP1A2; Environmental Exposure; Female; Follow-Up Studies; Humans; Male; Middle Aged; Mutagens; Rheology; Smoking; Theophylline; Time Factors; Uracil; Uric Acid; Urination; Xanthines	1999
Validity of an ELISA for N-acetyltransferase-2 (NAT2) phenotyping. Journal of immunological methods, 2001, May-01, Volume: 251, Issue:1-2 Topics: Arylamine N-Acetyltransferase; Caffeine; Chromatography, High Pressure Liquid; Enzyme-Linked Immunosorbent Assay; Genotype; Humans; Phenotype; Uracil; Xanthines	2001
[Determination of caffeine metabolite for the evaluation of N-acetyltransferase, CYP1A2 and xanthine oxidase activities]. Yao xue xue bao = Acta pharmaceutica Sinica, 1997, Volume: 32, Issue:11 Topics: Adolescent; Adult; Aged; Arylamine N-Acetyltransferase; Caffeine; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP1A2; Female; Humans; Male; Middle Aged; Theophylline; Uracil; Uric Acid; Xanthine Oxidase; Xanthines	1997
[HPLC determination of five caffeine metabolites]. Yao xue xue bao = Acta pharmaceutica Sinica, 1997, Volume: 32, Issue:8 Topics: Caffeine; Chromatography, High Pressure Liquid; Humans; Theophylline; Uracil; Uric Acid; Xanthines	1997
Relationship between metabolic phenotype of N-acetylation and bladder cancer. Chinese medical journal, 2000, Volume: 113, Issue:4 Topics: Acetylation; Adult; Caffeine; Female; Humans; Male; Middle Aged; Phenotype; Uracil; Urinary Bladder Neoplasms; Xanthines	2000
Severe 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) intoxication: insights into the measurement of hepatic cytochrome P450 1A2 induction. Clinical pharmacology and therapeutics, 2002, Volume: 72, Issue:2 Topics: Adult; Breath Tests; Caffeine; Case-Control Studies; Cytochrome P-450 CYP1A2; Environmental Pollutants; Enzyme Induction; Female; Humans; Liver; Male; Methylation; Polychlorinated Dibenzodioxins; Smoking; Teratogens; Theophylline; Uracil; Uric Acid; Xanthines	2002
Phenotyping of N-acetyltransferase type 2 by caffeine from uncontrolled dietary exposure. European journal of clinical pharmacology, 2004, Volume: 60, Issue:1 Topics: Acetylation; Administration, Oral; Adult; Arylamine N-Acetyltransferase; Caffeine; Chromatography, High Pressure Liquid; Diet; Female; Genotype; Humans; Male; Middle Aged; Phenotype; Spectrometry, Mass, Electrospray Ionization; Time Factors; Uracil; Uric Acid; Xanthines	2004
Re-investigation of the concordance of human NAT2 phenotypes and genotypes. Archives of toxicology, 2005, Volume: 79, Issue:4 Topics: Acetylation; Alleles; Arylamine N-Acetyltransferase; Caffeine; Central Nervous System Stimulants; Genotype; Humans; Phenotype; Reverse Transcriptase Polymerase Chain Reaction; Uracil; Xanthines	2005
[Determination of the activity of cytochrome P-450 CYP2A6 by HPLC method with caffeine as metabolizing probe]. Yao xue xue bao = Acta pharmaceutica Sinica, 2006, Volume: 41, Issue:3 Topics: Adult; Aryl Hydrocarbon Hydroxylases; Caffeine; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2A6; Female; Humans; Male; Mixed Function Oxygenases; Theophylline; Uracil; Uric Acid; Xanthines	2006
Concordance between the deduced acetylation status generated by high-speed: real-time PCR based NAT2 genotyping of seven single nucleotide polymorphisms and human NAT2 phenotypes determined by a caffeine assay. Clinica chimica acta; international journal of clinical chemistry, 2007, Volume: 376, Issue:1-2 Topics: Acetylation; Adult; Arylamine N-Acetyltransferase; Biotransformation; Caffeine; Genotype; Humans; Male; Middle Aged; Phenotype; Polymerase Chain Reaction; Polymorphism, Single Nucleotide; Uracil; Uric Acid; White People; Xanthines	2007
Caffeine N3-demethylation (CYP1A2) in a population with an increased exposure to polychlorinated biphenyls. European journal of clinical pharmacology, 2006, Volume: 62, Issue:12 Topics: Administration, Oral; Adolescent; Adult; Biometry; Caffeine; Cohort Studies; Cytochrome P-450 CYP1A2; Environmental Pollutants; Female; Genotype; Humans; Male; Methylation; Middle Aged; Polychlorinated Biphenyls; Sex Factors; Smoking; Uracil; Uric Acid; Xanthines	2006
In vivo evaluation of CYP1A2, CYP2A6, NAT-2 and xanthine oxidase activities in a Greek population sample by the RP-HPLC monitoring of caffeine metabolic ratios. Biomedical chromatography : BMC, 2007, Volume: 21, Issue:2 Topics: Adult; Aryl Hydrocarbon Hydroxylases; Arylamine N-Acetyltransferase; Caffeine; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2A6; Female; Humans; Male; Middle Aged; Mixed Function Oxygenases; Reproducibility of Results; Sensitivity and Specificity; Smoking; Theophylline; Uracil; Uric Acid; Xanthine Oxidase; Xanthines	2007
Phenotyping of N-acetyltransferase type 2 and xanthine oxidase with caffeine: when should urine samples be collected? European journal of clinical pharmacology, 2009, Volume: 65, Issue:4 Topics: Acetylation; Adult; Arylamine N-Acetyltransferase; Caffeine; Central Nervous System Stimulants; Humans; Male; Phenotype; Time Factors; Uracil; Uric Acid; White People; Xanthine Oxidase; Xanthines	2009
Inhibitory effects of caffeine and its metabolites on intracellular lipid accumulation in murine 3T3-L1 adipocytes. BioFactors (Oxford, England), 2008, Volume: 34, Issue:4 Topics: 3T3-L1 Cells; Adipocytes; Animals; Anti-Obesity Agents; Biological Transport; Caffeine; Cell Differentiation; Glucose; Insulin; Lipid Metabolism; Mice; Theophylline; Uracil; Uric Acid; Xanthines	2008
N-Acetyltransferase-2 (NAT2) gene polymorphisms and enzyme activity in Serbs: unprecedented high prevalence of rapid acetylators in a White population. Journal of clinical pharmacology, 2011, Volume: 51, Issue:7 Topics: Acetylation; Adolescent; Adult; Arylamine N-Acetyltransferase; Caffeine; Female; Genetic Association Studies; Haplotypes; Humans; Isoenzymes; Male; Middle Aged; Polymorphism, Genetic; Polymorphism, Single Nucleotide; Serbia; Uracil; Uric Acid; White People; Xanthines; Young Adult	2011
Comparison of N-acetyltransferase-2 enzyme genotype-phenotype and xanthine oxidase enzyme activity between Swedes and Koreans. Journal of clinical pharmacology, 2012, Volume: 52, Issue:10 Topics: Arylamine N-Acetyltransferase; Asian People; Caffeine; Contraceptives, Oral; Genotype; Humans; Phenotype; Polymorphism, Single Nucleotide; Sex Factors; Uracil; Uric Acid; White People; Xanthine Oxidase; Xanthines	2012
[Effect of Tibetan medicine zuotai on the activity, protein and mRNA expression of CYP1A2 and NAT2]. Yao xue xue bao = Acta pharmaceutica Sinica, 2014, Volume: 49, Issue:2 Topics: Administration, Oral; Animals; Arylamine N-Acetyltransferase; Caffeine; Cytochrome P-450 CYP1A2; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Female; Male; Medicine, Tibetan Traditional; Rats; Rats, Sprague-Dawley; RNA, Messenger; Theophylline; Uracil; Uric Acid; Xanthines	2014
Urine excretion of caffeine and select caffeine metabolites is common in the U.S. population and associated with caffeine intake. The Journal of nutrition, 2015, Volume: 145, Issue:4 Topics: Adolescent; Adult; Biomarkers; Black or African American; Caffeine; Child; Chromatography, Liquid; Cross-Sectional Studies; Female; Hispanic or Latino; Humans; Male; Middle Aged; Nutrition Surveys; Tandem Mass Spectrometry; Theophylline; Uracil; Uric Acid; White People; Xanthines; Young Adult	2015
N-Acetyltransferase-2 (NAT2) phenotype is influenced by genotype-environment interaction in Ethiopians. European journal of clinical pharmacology, 2018, Volume: 74, Issue:7 Topics: Adult; Arylamine N-Acetyltransferase; Black People; Caffeine; Ethiopia; Female; Gene-Environment Interaction; Genotype; Humans; Male; Phenotype; Polymorphism, Single Nucleotide; Sweden; Uracil; Uric Acid; Xanthines	2018