Page last updated: 2024-08-25

1-methylxanthine and allopurinol

1-methylxanthine has been researched along with allopurinol in 13 studies

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's6 (46.15)18.2507
2000's6 (46.15)29.6817
2010's1 (7.69)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chen, ST; Choong, KF; Hsieh, JF; Wu, SH; Yang, YL1
Gottehrer, A; Vaughan, LM1
Birkett, DJ; Day, RO; Miners, JO1
Hille, R; Kim, JH1
Hemann, C; Hille, R; Kim, JH1
Appleby, GJ; Clark, MG; Newman, JM; Rattigan, S; Tong, AC; Vincent, MA; Youd, JM1
Cao, XM; Ling, SS; Lu, JF; Yi, T; Zhuo, HT1
Clark, MG; Rattigan, S; Wallis, MG; Youd, JM1
Barrett, EJ; Clark, AD; Clark, MG; Dawson, D; Lindner, JR; Rattigan, S; Vincent, MA1
Asprodini, EK; Begas, E; Kouvaras, E; Papakosta, S; Tsakalof, A1
Burhenne, J; Göggelmann, C; Haefeli, WE; Mikus, G; Rengelshausen, J; Riedel, KD; Walter-Sack, I1
Fuhr, U; Jetter, A; Kinzig, M; Rodamer, M; Sörgel, F; Tomalik-Scharte, D1
Aklillu, E; Bertilsson, L; Carrillo, JA; Djordjevic, N; Karlsson, S; Roh, HK; Ueda, N1

Reviews

1 review(s) available for 1-methylxanthine and allopurinol

ArticleYear
Effect of xanthine-related compounds on a theophylline assay using theophylline oxidase.
    The Annals of pharmacotherapy, 1992, Volume: 26, Issue:12

    Topics: Allopurinol; Chromatography, High Pressure Liquid; Drug Interactions; Humans; Oxidoreductases; Oxypurinol; Pentoxifylline; Theophylline; Xanthines

1992

Trials

1 trial(s) available for 1-methylxanthine and allopurinol

ArticleYear
Reduction in non-glomerular renal clearance of the caffeine metabolite 1-methylxanthine by probenecid.
    International journal of clinical pharmacology and therapeutics, 2007, Volume: 45, Issue:8

    Topics: Adult; Area Under Curve; Arylamine N-Acetyltransferase; Caffeine; Central Nervous System Stimulants; Chromatography, High Pressure Liquid; Creatinine; Cross-Over Studies; Cytochrome P-450 CYP1A2; Depression, Chemical; Double-Blind Method; Female; Humans; Kidney; Male; Probenecid; Renal Agents; Spectrophotometry, Ultraviolet; Xanthine Oxidase; Xanthines

2007

Other Studies

11 other study(ies) available for 1-methylxanthine and allopurinol

ArticleYear
The screening and characterization of 6-aminopurine-based xanthine oxidase inhibitors.
    Bioorganic & medicinal chemistry, 2007, May-15, Volume: 15, Issue:10

    Topics: Allopurinol; Chromatography, High Pressure Liquid; Drug Evaluation, Preclinical; Enzyme Inhibitors; Kinetics; Magnetic Resonance Spectroscopy; Mass Spectrometry; Plant Leaves; Purines; Spectrophotometry, Ultraviolet; Structure-Activity Relationship; Triticum; Xanthine Oxidase

2007
1-Methylxanthine derived from theophylline as an in vivo biochemical probe of allopurinol effect.
    British journal of clinical pharmacology, 1991, Volume: 32, Issue:2

    Topics: Adult; Allopurinol; Biomarkers; Female; Humans; Male; Oxypurinol; Theophylline; Uric Acid; Xanthines

1991
Reductive half-reaction of xanthine oxidase with xanthine. Observation of a spectral intermediate attributable to the molybdenum center in the reaction of enzyme with xanthine.
    The Journal of biological chemistry, 1993, Jan-05, Volume: 268, Issue:1

    Topics: Animals; Binding Sites; Cattle; Electron Spin Resonance Spectroscopy; Female; Kinetics; Mathematics; Milk; Molybdenum; Spectrophotometry; Thermodynamics; Time Factors; Xanthine; Xanthine Oxidase; Xanthines

1993
Reductive half-reaction of xanthine oxidase: mechanistic role of the species giving rise to the "rapid type 1" molybdenum(V) electron paramagnetic resonance signal.
    Biochemistry, 1993, Apr-20, Volume: 32, Issue:15

    Topics: Animals; Cattle; Electron Spin Resonance Spectroscopy; Female; Flavin-Adenine Dinucleotide; Kinetics; Milk; Molybdenum; Oxidation-Reduction; Purines; Spectrophotometry; Time Factors; Xanthine; Xanthine Oxidase; Xanthines

1993
Increased metabolism of infused 1-methylxanthine by working muscle.
    Acta physiologica Scandinavica, 1999, Volume: 166, Issue:4

    Topics: Algorithms; Animals; Capillaries; Hindlimb; In Vitro Techniques; Lactic Acid; Male; Microspheres; Muscle, Skeletal; Oxygen Consumption; Perfusion; Physical Exertion; Rats; Rats, Wistar; Recruitment, Neurophysiological; Xanthine Oxidase; Xanthines

1999
[Determination of caffeine metabolite for the evaluation of N-acetyltransferase, CYP1A2 and xanthine oxidase activities].
    Yao xue xue bao = Acta pharmaceutica Sinica, 1997, Volume: 32, Issue:11

    Topics: Adolescent; Adult; Aged; Arylamine N-Acetyltransferase; Caffeine; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP1A2; Female; Humans; Male; Middle Aged; Theophylline; Uracil; Uric Acid; Xanthine Oxidase; Xanthines

1997
Exercise training improves insulin-mediated capillary recruitment in association with glucose uptake in rat hindlimb.
    Diabetes, 2001, Volume: 50, Issue:12

    Topics: Animals; Blood Flow Velocity; Blood Glucose; Capillaries; Femur; Glucose; Glucose Clamp Technique; Hindlimb; Insulin; Male; Muscle, Skeletal; Organ Size; Physical Exertion; Rats; Rats, Wistar; Vascular Resistance; Xanthine Oxidase; Xanthines

2001
Skeletal muscle microvascular recruitment by physiological hyperinsulinemia precedes increases in total blood flow.
    Diabetes, 2002, Volume: 51, Issue:1

    Topics: Animals; Biotransformation; Capillaries; Hindlimb; Hyperinsulinism; Infusions, Intravenous; Insulin; Kinetics; Male; Microcirculation; Muscle, Skeletal; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Uric Acid; Xanthine Oxidase; Xanthines

2002
In vivo evaluation of CYP1A2, CYP2A6, NAT-2 and xanthine oxidase activities in a Greek population sample by the RP-HPLC monitoring of caffeine metabolic ratios.
    Biomedical chromatography : BMC, 2007, Volume: 21, Issue:2

    Topics: Adult; Aryl Hydrocarbon Hydroxylases; Arylamine N-Acetyltransferase; Caffeine; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2A6; Female; Humans; Male; Middle Aged; Mixed Function Oxygenases; Reproducibility of Results; Sensitivity and Specificity; Smoking; Theophylline; Uracil; Uric Acid; Xanthine Oxidase; Xanthines

2007
Phenotyping of N-acetyltransferase type 2 and xanthine oxidase with caffeine: when should urine samples be collected?
    European journal of clinical pharmacology, 2009, Volume: 65, Issue:4

    Topics: Acetylation; Adult; Arylamine N-Acetyltransferase; Caffeine; Central Nervous System Stimulants; Humans; Male; Phenotype; Time Factors; Uracil; Uric Acid; White People; Xanthine Oxidase; Xanthines

2009
Comparison of N-acetyltransferase-2 enzyme genotype-phenotype and xanthine oxidase enzyme activity between Swedes and Koreans.
    Journal of clinical pharmacology, 2012, Volume: 52, Issue:10

    Topics: Arylamine N-Acetyltransferase; Asian People; Caffeine; Contraceptives, Oral; Genotype; Humans; Phenotype; Polymorphism, Single Nucleotide; Sex Factors; Uracil; Uric Acid; White People; Xanthine Oxidase; Xanthines

2012