Page last updated: 2024-08-25

1-methyluric acid and 3-methylxanthine

1-methyluric acid has been researched along with 3-methylxanthine in 23 studies

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-199012 (52.17)18.7374
1990's6 (26.09)18.2507
2000's2 (8.70)29.6817
2010's3 (13.04)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fuhr, U; Roots, I; Rost, KL; Staib, AH1
Guelen, PJ; Janssen, TJ; Vree, TB; Wijnands, GJ1
Berdel, D; Bonnacker, I; Süverkrüp, R; von Berg, A1
Beck, R; Knoppert, DC; MacLeod, SM; Spino, M; Thiessen, JJ1
Juan, D; Rammohan, M; Shin, SG1
Rogge, MC; Sedman, AJ; Solomon, WR; Toothaker, RD; Wagner, JG; Welling, PG1
Hafkenscheid, JC; Hekster, YA; Martea, M; Tiggeler, RG; Vree, TB1
Beckmann, J; Elsässer, W; Gundert-Remy, U; Hertrampf, R1
Levy, G; Ramzan, IM1
Bompadre, S; Ercolani, P; Leone, L1
Chakraborty, J; Marks, V; Scott, NR1
Berdel, D; Heimann, G1
Riegelman, S; Tang-Liu, DD; Williams, RL1
Konishi, H; Morita, K; Yamaji, A1
Iwaki, M; Ogiso, T; Okuyama, K; Tanino, T; Uno, S1
Norman, A; Rodopoulos, N1
Asoh, M; Kobayashi, S; Koitabashi, Y; Okano, YJ; Tateishi, T; Yamaguchi, A; Yoda, T1
Cao, W; Chen, G; Ling, SS; Zhuo, HT1
Kim, JQ; Park, HD; Park, KU; Song, J; Yoon, Y1
Gopishetty, S; Kale, Y; Louie, TM; Subramanian, M; Summers, R; Yu, CL1
Chae, JW; Kim, DH; Kim, Ej; Kwon, KI; Lee, BY1
Chen, XY; Liu, Y; Zhan, Y; Zhang, YF; Zhong, DF1
Cho, JY; Choi, CW; Kim, BI; Kim, EK; Kim, HS; Lee, J; Lee, JA; Oh, J; Park, EA; Shin, SH; Sohn, JA; Yu, KS1

Trials

3 trial(s) available for 1-methyluric acid and 3-methylxanthine

ArticleYear
Cystic fibrosis: enhanced theophylline metabolism may be linked to the disease.
    Clinical pharmacology and therapeutics, 1988, Volume: 44, Issue:3

    Topics: Adolescent; Adult; Biotransformation; Chromatography, High Pressure Liquid; Clinical Trials as Topic; Cystic Fibrosis; Double-Blind Method; Humans; Male; Random Allocation; Theophylline; Uric Acid; Xanthines

1988
[Peculiarities of the pharmacokinetics and pharmacodynamics of theophylline in children].
    Wiener klinische Wochenschrift, 1984, Aug-31, Volume: 96, Issue:16

    Topics: Adolescent; Asthma; Bronchitis; Caffeine; Child; Child, Preschool; Chromatography, High Pressure Liquid; Humans; Infant; Infant, Newborn; Infant, Premature; Kinetics; Theophylline; Uric Acid; Xanthines

1984
Effect of fluconazole on theophylline disposition in humans.
    European journal of clinical pharmacology, 1994, Volume: 46, Issue:4

    Topics: Adult; Cross-Over Studies; Enoxacin; Female; Fluconazole; Humans; Male; Metabolic Clearance Rate; Theophylline; Uric Acid; Xanthines

1994

Other Studies

20 other study(ies) available for 1-methyluric acid and 3-methylxanthine

ArticleYear
Theophylline metabolism affected by mexiletine.
    Clinical pharmacology and therapeutics, 1992, Volume: 52, Issue:1

    Topics: Adult; Caffeine; Humans; Male; Mexiletine; Theophylline; Uric Acid; Xanthines

1992
Drug-drug interactions affecting fluoroquinolones.
    The American journal of medicine, 1989, Dec-29, Volume: 87, Issue:6C

    Topics: Adult; Drug Interactions; Enoxacin; Humans; Male; Ofloxacin; Oxidation-Reduction; Theophylline; Uric Acid; Xanthines

1989
Renal clearance of theophylline and its major metabolites: age and urine flow dependency in paediatric patients.
    European journal of clinical pharmacology, 1989, Volume: 36, Issue:2

    Topics: Adolescent; Aging; Child; Child, Preschool; Female; Humans; Infant; Injections, Intravenous; Male; Theophylline; Uric Acid; Urodynamics; Xanthines

1989
Theophylline pharmacokinetics in normal elderly subjects.
    Clinical pharmacology and therapeutics, 1988, Volume: 44, Issue:5

    Topics: Adult; Aged; Aging; Chromatography, High Pressure Liquid; Humans; Infusions, Intravenous; Male; Theophylline; Uric Acid; Xanthines

1988
The theophylline-enoxacin interaction: I. Effect of enoxacin dose size on theophylline disposition.
    Clinical pharmacology and therapeutics, 1988, Volume: 44, Issue:5

    Topics: Adult; Chromatography, High Pressure Liquid; Drug Interactions; Enoxacin; Humans; Male; Theophylline; Uric Acid; Xanthines

1988
Pharmacokinetics of theophylline and its metabolites in a patient undergoing continuous ambulatory peritoneal dialysis.
    Clinical pharmacokinetics, 1988, Volume: 15, Issue:6

    Topics: Aged; Humans; Kidney Failure, Chronic; Male; Peritoneal Dialysis, Continuous Ambulatory; Theophylline; Uric Acid; Xanthines

1988
Enoxacin--a potent inhibitor of theophylline metabolism.
    European journal of clinical pharmacology, 1987, Volume: 33, Issue:3

    Topics: Adult; Anti-Infective Agents; Enoxacin; Humans; Naphthyridines; Theophylline; Uric Acid; Xanthines

1987
Kinetics of drug action in disease states. XVI. Pharmacodynamics of theophylline-induced seizures in rats.
    The Journal of pharmacology and experimental therapeutics, 1986, Volume: 236, Issue:3

    Topics: Animals; Brain; Dose-Response Relationship, Drug; Female; Half-Life; Kinetics; Rats; Rats, Inbred Lew; Seizures; Theophylline; Uric Acid; Xanthines

1986
[Determination of theophylline in the plasma by rapid solid-phase extraction].
    Bollettino della Societa italiana di biologia sperimentale, 1987, Aug-31, Volume: 63, Issue:8

    Topics: Chromatography, High Pressure Liquid; Humans; Lung Diseases, Obstructive; Theophylline; Uric Acid; Xanthines

1987
Urinary metabolites of caffeine in pregnant women.
    British journal of clinical pharmacology, 1986, Volume: 22, Issue:4

    Topics: Caffeine; Female; Humans; Pregnancy; Theophylline; Uric Acid; Xanthines

1986
Nonlinear theophylline elimination.
    Clinical pharmacology and therapeutics, 1982, Volume: 31, Issue:3

    Topics: Administration, Oral; Adult; Aminophylline; Biotransformation; Female; Humans; Infusions, Parenteral; Kinetics; Male; Models, Biological; Theophylline; Time Factors; Uric Acid; Xanthines

1982
Effect of mexiletine on elimination and metabolic conversion of theophylline and its major metabolites in rats.
    Biological & pharmaceutical bulletin, 1993, Volume: 16, Issue:2

    Topics: Administration, Oral; Aminophylline; Animals; In Vitro Techniques; Injections, Intravenous; Liver; Male; Mexiletine; Rats; Rats, Wistar; Theophylline; Uric Acid; Xanthines

1993
Elimination of theophylline metabolites in healthy adults.
    Scandinavian journal of clinical and laboratory investigation, 1997, Volume: 57, Issue:3

    Topics: Administration, Oral; Adult; Female; Humans; Male; Middle Aged; Theophylline; Time Factors; Uric Acid; Xanthines

1997
Developmental changes in urinary elimination of theophylline and its metabolites in pediatric patients.
    Pediatric research, 1999, Volume: 45, Issue:1

    Topics: Aging; Apnea; Asthma; Child, Preschool; Cytochrome P-450 CYP1A2; Humans; Infant; Infant, Newborn; Theophylline; Uric Acid; Xanthines

1999
Pharmacokinetics of theophylline metabolites in 8 Chinese patients.
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1998, Volume: 19, Issue:5

    Topics: Adult; Aminophylline; Asthma; Bronchodilator Agents; Circadian Rhythm; Humans; Middle Aged; Theophylline; Uric Acid; Xanthines

1998
High-throughput liquid chromatography-tandem mass spectrometry assay for plasma theophylline and its metabolites.
    Clinical chemistry, 2004, Volume: 50, Issue:11

    Topics: Bronchodilator Agents; Chromatography, Liquid; Humans; Mass Spectrometry; Plasma; Theophylline; Uric Acid; Xanthines

2004
Two distinct pathways for metabolism of theophylline and caffeine are coexpressed in Pseudomonas putida CBB5.
    Journal of bacteriology, 2009, Volume: 191, Issue:14

    Topics: Caffeine; Gene Expression; Metabolic Networks and Pathways; Pseudomonas putida; Theobromine; Theophylline; Uric Acid; Xanthine; Xanthines

2009
Development and validation of a sensitive LC-MS/MS method for the simultaneous quantitation of theophylline and its metabolites in rat plasma.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2012, Mar-15, Volume: 889-890

    Topics: Animals; Chromatography, Liquid; Drug Stability; Least-Squares Analysis; Rats; Reproducibility of Results; Sensitivity and Specificity; Tandem Mass Spectrometry; Theophylline; Uric Acid; Xanthines

2012
[Quantitative analysis of theophylline and its metabolites in urine of Chinese healthy subjects after oral administration of theophylline sustained-release tablets].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2014, Volume: 49, Issue:7

    Topics: Administration, Oral; Asian People; Calibration; Chromatography, Liquid; Delayed-Action Preparations; Healthy Volunteers; Humans; Spectrometry, Mass, Electrospray Ionization; Tablets; Tandem Mass Spectrometry; Theophylline; Uric Acid; Xanthines

2014
Prediction of serum theophylline concentrations and cytochrome P450 1A2 activity by analyzing urinary metabolites in preterm infants.
    British journal of clinical pharmacology, 2017, Volume: 83, Issue:6

    Topics: Aging; Apnea; Bronchodilator Agents; Cytochrome P-450 CYP1A2; Female; Genotype; Gestational Age; Humans; Infant; Infant, Newborn; Infant, Premature; Male; Theophylline; Uric Acid; Xanthines

2017