Page last updated: 2024-09-03

1-methylspermidine and spermine

1-methylspermidine has been researched along with spermine in 8 studies

Compound Research Comparison

Studies
(1-methylspermidine)
Trials
(1-methylspermidine)
Recent Studies (post-2010)
(1-methylspermidine)
Studies
(spermine)
Trials
(spermine)
Recent Studies (post-2010) (spermine)
20136,154251,056

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (50.00)18.2507
2000's3 (37.50)29.6817
2010's1 (12.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Coward, JK; Lakanen, JR; Pegg, AE1
Byers, TL; Hu, RH; Pegg, AE; Wechter, RS1
Byers, TL; Coward, JK; Lakanen, JR; Pegg, AE1
Hu, RH; Pegg, AE1
Alhonen, L; Herzig, KH; Janne, J; Keinanen, T; Khomutov, AR; Rasanen, TL; Sinervirta, R; Suppola, S; Vepsalainen, J1
Pillai, CK; Saminathan, M; Shirahata, A; Thomas, T; Thomas, TJ1
Alhonen, LI; Cerrada-Gimenez, M; Grigorenko, NA; Jänne, JE; Järvinen, AJ; Keinänen, TA; Khomutov, AR; Sinervirta, RM; Vepsäläinen, JJ1
Mandal, A; Mandal, S; Park, MH1

Other Studies

8 other study(ies) available for 1-methylspermidine and spermine

ArticleYear
alpha-Methyl polyamines: metabolically stable spermidine and spermine mimics capable of supporting growth in cells depleted of polyamines.
    Journal of medicinal chemistry, 1992, Feb-21, Volume: 35, Issue:4

    Topics: Animals; Cell Division; Cell Line, Transformed; Colonic Neoplasms; Eflornithine; Humans; Leukemia L1210; Methylation; Mice; Putrescine; Spermidine; Spermine; Spermine Synthase; Substrate Specificity; Tumor Cells, Cultured

1992
Effects of the S-adenosylmethionine decarboxylase inhibitor, 5'-([(Z)-4-amino-2-butenyl]methylamino)-5'-deoxyadenosine, on cell growth and polyamine metabolism and transport in Chinese hamster ovary cell cultures.
    The Biochemical journal, 1994, Oct-01, Volume: 303 ( Pt 1)

    Topics: Adenosylmethionine Decarboxylase; Animals; Biological Transport; Cell Division; CHO Cells; Cricetinae; Cycloheximide; Deoxyadenosines; Eflornithine; Kinetics; Polyamines; Putrescine; Spermidine; Spermine

1994
The role of hypusine depletion in cytostasis induced by S-adenosyl-L-methionine decarboxylase inhibition: new evidence provided by 1-methylspermidine and 1,12-dimethylspermine.
    The Biochemical journal, 1994, Oct-15, Volume: 303 ( Pt 2)

    Topics: Adenosylmethionine Decarboxylase; Animals; Cell Division; CHO Cells; Chromatography, High Pressure Liquid; Cricetinae; Deoxyadenosines; Eflornithine; Eukaryotic Translation Initiation Factor 5A; Leukemia L1210; Lysine; Oxidoreductases Acting on CH-NH Group Donors; Peptide Initiation Factors; RNA-Binding Proteins; Spermidine; Spermine; Substrate Specificity; Tumor Cells, Cultured

1994
Rapid induction of apoptosis by deregulated uptake of polyamine analogues.
    The Biochemical journal, 1997, Nov-15, Volume: 328 ( Pt 1)

    Topics: Alkylation; Animals; Apoptosis; Cell Death; CHO Cells; Cricetinae; Cycloheximide; Cysteine Proteinase Inhibitors; Eflornithine; Oxidoreductases Acting on CH-NH Group Donors; Polyamines; Putrescine; Spermidine; Spermine

1997
A polyamine analogue prevents acute pancreatitis and restores early liver regeneration in transgenic rats with activated polyamine catabolism.
    The Journal of biological chemistry, 2002, Oct-18, Volume: 277, Issue:42

    Topics: alpha-Amylases; Animals; Animals, Genetically Modified; Immunohistochemistry; Liver; Mice; Pancreatitis; Polyamines; Proliferating Cell Nuclear Antigen; Protein Binding; Rats; Regeneration; Spermidine; Spermine; Time Factors; Zinc

2002
Polyamine structural effects on the induction and stabilization of liquid crystalline DNA: potential applications to DNA packaging, gene therapy and polyamine therapeutics.
    Nucleic acids research, 2002, Sep-01, Volume: 30, Issue:17

    Topics: Animals; Cattle; Crystallization; DNA; Genetic Therapy; Methenamine; Microscopy, Polarization; Nucleic Acid Conformation; Polyamines; Spermidine; Spermine; Structure-Activity Relationship; Thymus Gland

2002
Alpha-methyl polyamines: efficient synthesis and tolerance studies in vivo and in vitro. First evidence for dormant stereospecificity of polyamine oxidase.
    Journal of medicinal chemistry, 2006, Jan-12, Volume: 49, Issue:1

    Topics: Animals; Animals, Genetically Modified; Dose-Response Relationship, Drug; Drug Tolerance; Fibroblasts; Humans; In Vitro Techniques; Kidney; Liver; Mice; Molecular Structure; Oxidoreductases Acting on CH-NH Group Donors; Pancreas; Polyamine Oxidase; Rats; Recombinant Proteins; Spermidine; Spermine; Stereoisomerism; Structure-Activity Relationship; Substrate Specificity

2006
Depletion of the polyamines spermidine and spermine by overexpression of spermidine/spermine N¹-acetyltransferase 1 (SAT1) leads to mitochondria-mediated apoptosis in mammalian cells.
    The Biochemical journal, 2015, Jun-15, Volume: 468, Issue:3

    Topics: Acetyltransferases; Antimetabolites; Apoptosis; Apoptosis Regulatory Proteins; Cell Proliferation; Cell Shape; Cell Size; HEK293 Cells; Humans; In Situ Nick-End Labeling; Kidney; Kinetics; Membrane Potential, Mitochondrial; Microscopy, Electron, Transmission; Mitochondria; Recombinant Proteins; Spermidine; Spermine

2015