Page last updated: 2024-09-03

1-methylspermidine and putrescine

1-methylspermidine has been researched along with putrescine in 5 studies

Compound Research Comparison

Studies
(1-methylspermidine)
Trials
(1-methylspermidine)
Recent Studies (post-2010)
(1-methylspermidine)
Studies
(putrescine)
Trials
(putrescine)
Recent Studies (post-2010) (putrescine)
20134,64327826

Protein Interaction Comparison

ProteinTaxonomy1-methylspermidine (IC50)putrescine (IC50)
Chain A, S-ADENOSYLMETHIONINE DECARBOXYLASE ALPHA CHAINHomo sapiens (human)0.2001
Chain B, S-ADENOSYLMETHIONINE DECARBOXYLASE BETA CHAINHomo sapiens (human)0.2001
Chain A, S-ADENOSYLMETHIONINE DECARBOXYLASE ALPHA CHAINHomo sapiens (human)0.2001
Chain B, S-ADENOSYLMETHIONINE DECARBOXYLASE BETA CHAINHomo sapiens (human)0.2001

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (80.00)18.2507
2000's0 (0.00)29.6817
2010's1 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Coward, JK; Lakanen, JR; Pegg, AE1
Byers, TL; Hu, RH; Pegg, AE; Wechter, RS1
Coward, JK; Lakanen, JR; Pegg, AE; Poulin, R1
Hu, RH; Pegg, AE1
Alhonen, L; Cerrada-Gimenez, M; Jänne, J; Keinänen, TA; Khomutov, AR; Pietilä, M; Pirinen, E; Uimari, A; Vuohelainen, S1

Other Studies

5 other study(ies) available for 1-methylspermidine and putrescine

ArticleYear
alpha-Methyl polyamines: metabolically stable spermidine and spermine mimics capable of supporting growth in cells depleted of polyamines.
    Journal of medicinal chemistry, 1992, Feb-21, Volume: 35, Issue:4

    Topics: Animals; Cell Division; Cell Line, Transformed; Colonic Neoplasms; Eflornithine; Humans; Leukemia L1210; Methylation; Mice; Putrescine; Spermidine; Spermine; Spermine Synthase; Substrate Specificity; Tumor Cells, Cultured

1992
Effects of the S-adenosylmethionine decarboxylase inhibitor, 5'-([(Z)-4-amino-2-butenyl]methylamino)-5'-deoxyadenosine, on cell growth and polyamine metabolism and transport in Chinese hamster ovary cell cultures.
    The Biochemical journal, 1994, Oct-01, Volume: 303 ( Pt 1)

    Topics: Adenosylmethionine Decarboxylase; Animals; Biological Transport; Cell Division; CHO Cells; Cricetinae; Cycloheximide; Deoxyadenosines; Eflornithine; Kinetics; Polyamines; Putrescine; Spermidine; Spermine

1994
Enhancement of the spermidine uptake system and lethal effects of spermidine overaccumulation in ornithine decarboxylase-overproducing L1210 cells under hyposmotic stress.
    The Journal of biological chemistry, 1993, Mar-05, Volume: 268, Issue:7

    Topics: Animals; Biological Transport; Cell Division; Cell Survival; Leukemia L1210; Mice; Ornithine Decarboxylase; Osmotic Pressure; Putrescine; Spermidine; Tumor Cells, Cultured

1993
Rapid induction of apoptosis by deregulated uptake of polyamine analogues.
    The Biochemical journal, 1997, Nov-15, Volume: 328 ( Pt 1)

    Topics: Alkylation; Animals; Apoptosis; Cell Death; CHO Cells; Cricetinae; Cycloheximide; Cysteine Proteinase Inhibitors; Eflornithine; Oxidoreductases Acting on CH-NH Group Donors; Polyamines; Putrescine; Spermidine; Spermine

1997
Spermidine is indispensable in differentiation of 3T3-L1 fibroblasts to adipocytes.
    Journal of cellular and molecular medicine, 2010, Volume: 14, Issue:6B

    Topics: 3T3-L1 Cells; Adipocytes; Adipogenesis; Animals; Cell Differentiation; Cell Proliferation; Cell Shape; Eflornithine; Fibroblasts; Gene Expression Regulation; Glucose Transporter Type 4; Isomerism; Lipid Metabolism; Mice; Organ Specificity; Putrescine; Spermidine; Time Factors

2010