Page last updated: 2024-08-22

1-methylpyrene and 1-hydroxymethylpyrene

1-methylpyrene has been researched along with 1-hydroxymethylpyrene in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (25.00)18.2507
2000's0 (0.00)29.6817
2010's4 (50.00)24.3611
2020's2 (25.00)2.80

Authors

AuthorsStudies
Flesher, JW; Horn, J; Lehner, AF1
Doehmer, J; Engst, W; Glatt, H; Hermersdörfer, H; Landsiedel, R1
Bendadani, C; Dobbernack, G; Glatt, H; Meinl, W; Monien, BH1
Chen, D; Hu, K; Jiang, H; Lai, Y; Liu, B; Liu, Y1
Albert, K; Bendadani, C; Glatt, H; Monien, BH; Steinhauser, L1
Glatt, H; Jia, H; Liu, Y; Zhang, C1
Chen, Y; Hu, K; Li, Z; Liu, Y; Zhu, N1
Glatt, H; Li, Z; Liu, J; Liu, Y; Song, M; Yu, H1

Other Studies

8 other study(ies) available for 1-methylpyrene and 1-hydroxymethylpyrene

ArticleYear
1-Sulfooxymethylpyrene is an electrophilic mutagen and ultimate carcinogen of 1-methyl- and 1-hydroxymethylpyrene.
    Biochemical and biophysical research communications, 1996, Nov-01, Volume: 228, Issue:1

    Topics: Animals; Carcinogenicity Tests; Carcinogens; Female; Fibroadenoma; Mutagenicity Tests; Mutagens; Pyrenes; Rats; Rats, Sprague-Dawley; Sarcoma

1996
Benzylic hydroxylation of 1-methylpyrene and 1-ethylpyrene by human and rat cytochromes P450 individually expressed in V79 Chinese hamster cells.
    Carcinogenesis, 1999, Volume: 20, Issue:9

    Topics: Animals; Biotransformation; Carcinogens, Environmental; Cell Line; Cricetinae; Cricetulus; Cytochrome P-450 Enzyme System; Ethanol; Humans; Hydroxylation; Isoenzymes; Lung; Microsomes, Liver; Pyrenes; Rats; Recombinant Fusion Proteins; Species Specificity; Structure-Activity Relationship

1999
The carcinogen 1-methylpyrene forms benzylic DNA adducts in mouse and rat tissues in vivo via a reactive sulphuric acid ester.
    Archives of toxicology, 2014, Volume: 88, Issue:3

    Topics: Animals; Arylsulfotransferase; Carcinogens; Deoxyadenosines; Deoxyguanosine; DNA Adducts; Female; Humans; Inactivation, Metabolic; Male; Mice; Mice, Transgenic; Pyrenes; Rats; Rats, Wistar; Sulfuric Acids

2014
Genotoxicity of 1-methylpyrene and 1-hydroxymethylpyrene in Chinese hamster V79-derived cells expressing both human CYP2E1 and SULT1A1.
    Environmental and molecular mutagenesis, 2015, Volume: 56, Issue:4

    Topics: Animals; Arylsulfotransferase; Cell Line; Cell Survival; Cricetinae; Cricetulus; Cytochrome P-450 Enzyme System; Cytochrome P450 Family 2; Dose-Response Relationship, Drug; Humans; Hypoxanthine Phosphoribosyltransferase; Micronucleus Tests; Mutagenicity Tests; Mutagens; Mutation Rate; Pentachlorophenol; Pyrenes

2015
Metabolism and excretion of 1-hydroxymethylpyrene, the proximate metabolite of the carcinogen 1-methylpyrene, in rats.
    Toxicology, 2016, 07-29, Volume: 366-367

    Topics: Animals; Carboxylic Acids; Carcinogens; Chromatography, High Pressure Liquid; DNA Damage; Dose-Response Relationship, Drug; Feces; Magnetic Resonance Spectroscopy; Male; Molecular Structure; Pyrenes; Rats; Rats, Wistar

2016
Role of exposure/recovery schedule in micronuclei induction by several promutagens in V79-derived cells expressing human CYP2E1 and SULT1A1.
    Mutation research. Genetic toxicology and environmental mutagenesis, 2016, Sep-15, Volume: 808

    Topics: Animals; Arylsulfotransferase; Catechols; Cell Line; Cricetulus; Cytochrome P450 Family 2; Humans; Hydroquinones; Inactivation, Metabolic; Micronucleus Tests; Mitosis; Mutagens; Pyrenes

2016
Micronuclei Formation by Promutagens in Metabolism-Incompetent V79 Cells Interacting With Activation-Proficient Cells in Various Experimental Settings.
    Environmental and molecular mutagenesis, 2020, Volume: 61, Issue:2

    Topics: Aflatoxin B1; Animals; Arylsulfotransferase; Benzo(a)pyrene; Cell Line; Cricetinae; Cytochrome P-450 Enzyme System; Humans; Micronuclei, Chromosome-Defective; Micronucleus Tests; Mutagens; Pyrenes

2020
Potent aneugenicity of 1-methylpyrene in human cells dependent on metabolic activation by endogenous enzymes.
    Archives of toxicology, 2021, Volume: 95, Issue:2

    Topics: Activation, Metabolic; Aneugens; Cell Line, Tumor; Centromere Protein B; Centrosome; Hep G2 Cells; Humans; Micronuclei, Chromosome-Defective; Micronucleus Tests; Microscopy, Fluorescence; Mitosis; Mutagens; Pyrenes; Spindle Apparatus

2021