1-methyl-4-phenylpyridinium has been researched along with cytochrome c-t in 36 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 22 (61.11) | 29.6817 |
| 2010's | 14 (38.89) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Anantharam, V; Kanthasamy, A; Kanthasamy, AG; Kaul, S; Kitazawa, M | 1 |
| Cooper, JM; Gu, M; Iravani, MM; Irvani, M; Jenner, P; King, D; Schapira, AH | 1 |
| Chee, JL; Dong, B; Guan, XL; Lee, JY; Leong, SM; Lim, TM; Liou, AK; Ong, EH | 1 |
| Wang, XJ; Xu, JX | 1 |
| Bezard, E; Xie, YX; Zhao, BL | 1 |
| Han, ES; Kim, YJ; Ko, HH; Lee, CS | 3 |
| Han, ES; Kim, YK; Lee, CS | 1 |
| Han, ES; Lee, CS; Song, JH; Yim, SB | 1 |
| Bang, H; Han, ES; Han, YS; Lee, CS; Lee, DH | 1 |
| Lim, HS; Lu, XY; Paz, J; Yao, H; Zhang, W | 1 |
| Ahn, CW; Cha, BS; Jung, TW; Kang, ES; Kim, SK; Lee, HC; Lee, JY; Shim, WS | 1 |
| Beart, PM; Lim, ML; Mercer, LD; Nagley, P | 1 |
| Cho, SH; Chung, YH; Kim, DH; Kim, KY; Kim, SS; Lee, DY; Lee, HJ; Lee, JY; Lee, KS; Lee, WB; Noh, YH; Yoon, OJ | 1 |
| Cardoso, SM; Domingues, AF; Esteves, AR; Ferreira, IL; Januário, C; Oliveira, CR; Swerdlow, RH | 1 |
| Ding, JH; Hu, G; Wang, ZY; Zhang, S; Zhou, F; Zhou, XQ | 1 |
| Aguilera, J; Chaïb-Oukadour, I; Gil, C; Ortega, A; Rodríguez-Alvarez, J | 1 |
| Bournival, J; Martinoli, MG; Quessy, P | 1 |
| Jin, GZ; Jung, HW; Kim, SY; Kim, YS; Park, YK | 1 |
| Kobayashi, S; Matsushima, H; Mitsumoto, Y; Muroyama, A; Yoshimura, I | 1 |
| Feng, L; Li, Z; Liu, S; Lu, G; Meng, H; Poon, WS; Wang, A; Wu, F | 1 |
| Ding, J; Duan, L; Hu, G; Huang, X; Qian, X; Xie, J | 1 |
| Han, R; Han, Y; Hu, S; Mak, S | 1 |
| Chen, RQ; Fang, HR; Hu, B; Li, YJ; Ren, YK; Tang, XQ; Wang, CY; Zhou, CF | 1 |
| Ahn, CH; Kim, DJ; Kost, GC; Lee, YB; Selvaraj, S; Singh, BB | 1 |
| Deng, Q; Yang, X | 1 |
| Song, B; Song, Z; Xu, S; Zhang, Q | 1 |
| Jia, Y; Lu, H; Lu, J; Peng, T; Teng, J; Wang, J | 1 |
| Chen, C; Chen, X; Huang, W; Li, D; Si, E; Wang, J; Wang, Y; Ye, Q | 1 |
| Liu, K; Sun, P; Xiang, H; Xie, J; Xu, H | 1 |
| Chu, H; Lan, K; Leng, C; Ning, J; Song, T; Wang, S | 1 |
| Choi, DK; Ganesan, P; Kim, IS | 1 |
| Du, XX; Jiang, H; Li, Y; Shen, XL; Song, N; Xie, JX | 1 |
| Gu, C; Hu, Q; Liu, CF; Ren, H; Wang, G; Wu, J; Zhang, Y | 1 |
| Araki, M; Kurashige, T; Maruyama, H; Matsumoto, M; Nagano, Y; Nakamura, T; Obayashi, H; Shishido, T; Takahashi, T | 1 |
36 other study(ies) available for 1-methyl-4-phenylpyridinium and cytochrome c-t
| Article | Year |
|---|---|
Caspase-3 dependent proteolytic activation of protein kinase C delta mediates and regulates 1-methyl-4-phenylpyridinium (MPP+)-induced apoptotic cell death in dopaminergic cells: relevance to oxidative stress in dopaminergic degeneration.
Topics: 1-Methyl-4-phenylpyridinium; Animals; Apoptosis; Benzimidazoles; Caspase 3; Caspase 9; Caspase Inhibitors; Caspases; Cell Line; Coumarins; Cytochromes c; DNA Fragmentation; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Flow Cytometry; Free Radical Scavengers; Gene Expression; Herbicides; In Vitro Techniques; Manganese Compounds; Mesencephalon; Metalloporphyrins; Nerve Degeneration; Organometallic Compounds; Oxidative Stress; Precipitin Tests; Protein Kinase C; Protein Kinase C-delta; Rats; Reactive Oxygen Species; Time Factors; Transfection | 2003 |
Pramipexole protects against apoptotic cell death by non-dopaminergic mechanisms.
Topics: 1-Methyl-4-phenylpyridinium; Aconitate Hydratase; Antioxidants; Benzothiazoles; Carbocyanines; Caspase 3; Caspases; Cell Count; Cell Death; Cell Line, Tumor; Cell Survival; Cytochromes c; Dose-Response Relationship, Drug; Drug Interactions; Flow Cytometry; Humans; Jurkat Cells; L-Lactate Dehydrogenase; Mitochondria; Necrosis; Neuroblastoma; Pramipexole; Rotenone; Thiazoles | 2004 |
Compensatory caspase activation in MPP+-induced cell death in dopaminergic neurons.
Topics: 1-Methyl-4-phenylpyridinium; Animals; Apoptosis; Apoptosis Inducing Factor; Caspase 2; Caspase 3; Caspase 6; Caspase 7; Caspase 8; Caspase 9; Caspases; Cell Line; Cytochromes c; Dopamine; Enzyme Activation; Flavoproteins; Membrane Proteins; Mice; Mitochondria; Neurons | 2005 |
Salvianic acid A protects human neuroblastoma SH-SY5Y cells against MPP+-induced cytotoxicity.
Topics: 1-Methyl-4-phenylpyridinium; Apoptosis; bcl-2-Associated X Protein; Bisbenzimidazole; Blotting, Western; Caffeic Acids; Caspase 3; Caspases; Catalase; Cell Line, Tumor; Cell Nucleus; Cell Survival; Cytochromes c; Dithioerythritol; Dose-Response Relationship, Drug; Drug Interactions; Flow Cytometry; Humans; Lactates; Membrane Potentials; Mitochondria; Necrosis; Neuroblastoma; Neuroprotective Agents; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; Sulfhydryl Reagents; Superoxide Dismutase | 2005 |
Investigating the receptor-independent neuroprotective mechanisms of nicotine in mitochondria.
Topics: 1-Methyl-4-phenylpyridinium; Animals; Binding Sites; Blotting, Western; Brain; Calcium; Cell Line; Cell Line, Tumor; Cytochromes c; Dose-Response Relationship, Drug; Electrons; Free Radicals; Green Fluorescent Proteins; Humans; Hydrogen Peroxide; Intracellular Membranes; Male; Membrane Potentials; Microscopy, Confocal; Mitochondria; Mitochondrial Swelling; Nicotine; Oxidopamine; Oxygen; Permeability; Plasmids; Rats; Rats, Sprague-Dawley; Spectrophotometry; Time Factors | 2005 |
Inhibition of 1-methyl-4-phenylpyridinium-induced mitochondrial dysfunction and cell death in PC12 cells by sulfonylurea glibenclamide.
Topics: 1-Methyl-4-phenylpyridinium; Acetylcysteine; Animals; Apoptosis; Benzoates; Caspase 3; Caspases; Catalase; Cell Nucleus; Cell Survival; Cytochromes c; DNA Fragmentation; Dose-Response Relationship, Drug; Enzyme Activation; Glutathione; Glyburide; Imidazoles; Mitochondrial Membranes; PC12 Cells; Permeability; Porphyrins; Rats; Reactive Oxygen Species; Tolbutamide | 2005 |
Piperine inhibition of 1-methyl-4-phenylpyridinium-induced mitochondrial dysfunction and cell death in PC12 cells.
Topics: 1-Methyl-4-phenylpyridinium; Alkaloids; Animals; Benzodioxoles; Caspase 3; Caspases; Cell Death; Cell Membrane Permeability; Cytochromes c; DNA Fragmentation; Glutathione; Lipid Peroxidation; Malondialdehyde; Membrane Potentials; Mitochondria; Mitochondrial Membranes; PC12 Cells; Piperidines; Polyunsaturated Alkamides; Rats; Reactive Oxygen Species; Thiobarbituric Acid Reactive Substances | 2006 |
Econazole attenuates cytotoxicity of 1-methyl-4-phenylpyridinium by suppressing mitochondrial membrane permeability transition.
Topics: 1-Methyl-4-phenylpyridinium; Animals; Apoptosis; Calcium; Caspase 3; Caspases; Cell Survival; Cytochromes c; Dose-Response Relationship, Drug; Drug Interactions; Econazole; Flow Cytometry; Herbicides; Membrane Potentials; Mitochondrial Membranes; PC12 Cells; Permeability; Rats; Reactive Oxygen Species | 2006 |
Differential involvement of intracellular Ca2+ in 1-methyl-4-phenylpyridinium- or 6-hydroxydopamine-induced cell viability loss in PC12 cells.
Topics: 1-Methyl-4-phenylpyridinium; Animals; Calcium; Calmodulin; Cell Death; Chelating Agents; Cytochromes c; Egtazic Acid; Glutathione; Mitochondria; Nicardipine; Oxidopamine; PC12 Cells; Rats; Reactive Oxygen Species; Sulfonamides | 2006 |
The neuroprotective role of attractin in neurodegeneration.
Topics: 1-Methyl-4-phenylpyridinium; Acetylcysteine; Analysis of Variance; Apoptosis Inducing Factor; Cell Line, Tumor; Cell Survival; Cytochromes c; Gene Expression Regulation; Humans; In Situ Hybridization; Membrane Proteins; Nerve Degeneration; Neurotoxins; RNA, Small Interfering; Transfection; Tyrosine 3-Monooxygenase | 2007 |
Modulation of 1-methyl-4-phenylpyridinium-induced mitochondrial dysfunction and cell death in PC12 cells by K(ATP) channel block.
Topics: 1-Methyl-4-phenylpyridinium; Animals; Caspase 3; Cell Death; Cell Membrane Permeability; Cell Nucleus; Cell Survival; Cytochromes c; Decanoic Acids; Glutathione; Glyburide; Herbicides; Hydroxy Acids; Mitochondria; Mitochondrial Membranes; Nerve Degeneration; Neurons; Neuroprotective Agents; Oxidative Stress; PC12 Cells; Potassium Channel Blockers; Potassium Channels; Rats; Reactive Oxygen Species | 2007 |
Rosiglitazone protects human neuroblastoma SH-SY5Y cells against MPP+ induced cytotoxicity via inhibition of mitochondrial dysfunction and ROS production.
Topics: 1-Methyl-4-phenylpyridinium; bcl-2-Associated X Protein; Caspase 3; Cell Line, Tumor; Cytochromes c; Herbicides; Humans; Hypoglycemic Agents; Mitochondria; Neuroblastoma; Neurons; Neuroprotective Agents; Oxidative Stress; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; RNA, Messenger; Rosiglitazone; Thiazolidinediones | 2007 |
Lamotrigine inhibition of rotenone- or 1-methyl-4-phenylpyridinium-induced mitochondrial damage and cell death.
Topics: 1-Methyl-4-phenylpyridinium; Animals; Apoptosis; Caspase 3; Cell Death; Cell Membrane Permeability; Cytochromes c; Electron Transport Complex I; Enzyme Activation; Excitatory Amino Acid Antagonists; Glutathione; Lamotrigine; Membrane Potential, Mitochondrial; Mitochondria; Nerve Degeneration; Neurons; Neurotoxins; Oxidative Stress; PC12 Cells; Rats; Reactive Oxygen Species; Rotenone; Triazines | 2007 |
Rotenone and MPP+ preferentially redistribute apoptosis-inducing factor in apoptotic dopamine neurons.
Topics: 1-Methyl-4-phenylpyridinium; Animals; Apoptosis; Apoptosis Inducing Factor; Cells, Cultured; Cytochromes c; Dopamine; Embryo, Mammalian; Herbicides; Mesencephalon; Mitochondria; Neurons; Rats; Rotenone; Time Factors; Tyrosine 3-Monooxygenase | 2007 |
Kynurenic acid attenuates MPP(+)-induced dopaminergic neuronal cell death via a Bax-mediated mitochondrial pathway.
Topics: 1-Methyl-4-phenylpyridinium; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Caspase 9; Cell Line, Tumor; Cytochromes c; Dopamine; Enzyme Activation; Humans; Kynurenic Acid; Membrane Potential, Mitochondrial; Mitochondria; Nerve Degeneration; Neurons; Time Factors | 2008 |
Mitochondrial function in Parkinson's disease cybrids containing an nt2 neuron-like nuclear background.
Topics: 1-Methyl-4-phenylpyridinium; Adenosine Triphosphate; Aged; Blood Platelets; Case-Control Studies; Caspase 3; Cell Line, Tumor; Cell Nucleus; Cell Survival; Citrate (si)-Synthase; Cytochromes c; DNA, Mitochondrial; Dose-Response Relationship, Drug; Electron Transport Complex IV; Enzyme Activation; Humans; Hybrid Cells; L-Lactate Dehydrogenase; Membrane Potential, Mitochondrial; Middle Aged; Mitochondria; Neurons; Parkinson Disease; Teratocarcinoma | 2008 |
Iptakalim ameliorates MPP+-induced astrocyte mitochondrial dysfunction by increasing mitochondrial complex activity besides opening mitoK(ATP) channels.
Topics: 1-Methyl-4-phenylpyridinium; Adenosine Triphosphate; Analysis of Variance; Animals; Astrocytes; Blotting, Western; Cell Respiration; Cells, Cultured; Cytochromes c; Diazoxide; Electron Transport Complex I; Electron Transport Complex IV; Mitochondria; Neurotoxins; Potassium Channels; Propylamines; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species | 2009 |
Tetanus toxin H(C) fragment reduces neuronal MPP+ toxicity.
Topics: 1-Methyl-4-phenylpyridinium; Animals; Apoptosis; Caspase 3; Cell Culture Techniques; Cytochromes c; Extracellular Signal-Regulated MAP Kinases; Neuromuscular Blocking Agents; Neurons; NF-kappa B; Peptide Fragments; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Signal Transduction; Tetanus Toxin | 2009 |
Protective effects of resveratrol and quercetin against MPP+ -induced oxidative stress act by modulating markers of apoptotic death in dopaminergic neurons.
Topics: 1-Methyl-4-phenylpyridinium; Animals; Apoptosis; Apoptosis Inducing Factor; bcl-2-Associated X Protein; Biomarkers; Blotting, Western; Cell Nucleus; Cytochromes c; Dopamine; Fluorescent Antibody Technique; Gene Expression Regulation; Kinetics; Neurons; Neuroprotective Agents; Oxidative Stress; PC12 Cells; Protein Transport; Quercetin; Rats; Resveratrol; RNA, Messenger; Stilbenes | 2009 |
Neuroprotective effect of methanol extract of Phellodendri Cortex against 1-methyl-4-phenylpyridinium (MPP+)-induced apoptosis in PC-12 cells.
Topics: 1-Methyl-4-phenylpyridinium; Animals; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Caspase Inhibitors; Cell Nucleus Shape; Cell Survival; Cytochromes c; Methanol; Neurons; Neuroprotective Agents; Phellodendron; Plant Extracts; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Proto-Oncogene Proteins c-bcl-2; Rats; RNA, Messenger | 2009 |
Oral administration of coenzyme Q(10) prevents cytochrome c release from mitochondria induced by 1-methyl-4-phenylpyridinium ion in mouse brain synaptosomes.
Topics: 1-Methyl-4-phenylpyridinium; Administration, Oral; Animals; Brain; Cytochromes c; Male; Membrane Potential, Mitochondrial; Mice; Mice, Inbred C57BL; Mitochondria; Neuroprotective Agents; Oxidation-Reduction; Synaptosomes; Ubiquinone | 2009 |
Alpha-synuclein knockdown attenuates MPP+ induced mitochondrial dysfunction of SH-SY5Y cells.
Topics: 1-Methyl-4-phenylpyridinium; alpha-Synuclein; bcl-2-Associated X Protein; Cell Line, Tumor; Cell Nucleus Shape; Cell Survival; Central Nervous System Agents; Cytochromes c; Gene Knockdown Techniques; Humans; Inverted Repeat Sequences; Membrane Potential, Mitochondrial; Mitochondria; Mitochondrial Diseases; Neurons; Proto-Oncogene Proteins c-bcl-2; RNA, Messenger | 2009 |
K(ATP) channel openers protect mesencephalic neurons against MPP+-induced cytotoxicity via inhibition of ROS production.
Topics: 1-Methyl-4-phenylpyridinium; Animals; Cells, Cultured; Cromakalim; Cytochromes c; Diazoxide; Dopamine; KATP Channels; Membrane Transport Modulators; Mesencephalon; Mice; Mice, Inbred C57BL; Mitochondria; Neurons; Neuroprotective Agents; Neurotoxins; Oxidative Stress; Pinacidil; Potassium Channels, Inwardly Rectifying; Reactive Oxygen Species | 2010 |
Protection against 1-methyl-4-phenylpyridinium ion (MPP+)-induced apoptosis by water extract of ginseng (Panax ginseng C.A. Meyer) in SH-SY5Y cells.
Topics: 1-Methyl-4-phenylpyridinium; Antioxidants; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Cell Line, Tumor; Cytochromes c; Drug Evaluation, Preclinical; Enzyme Inhibitors; Herbicides; Humans; Mitochondria; Neuroblastoma; Neurotoxins; Panax; Parkinson Disease; Phytotherapy; Plant Extracts; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species | 2011 |
Endogenous hydrogen sulfide is involved in asymmetric dimethylarginine-induced protection against neurotoxicity of 1-methyl-4-phenyl-pyridinium ion.
Topics: 1-Methyl-4-phenylpyridinium; Aminooxyacetic Acid; Animals; Antioxidants; Arginine; Cyclin D1; Cystathionine beta-Synthase; Cytochromes c; Down-Regulation; Hydrogen Sulfide; Membrane Potential, Mitochondrial; Neuroprotective Agents; PC12 Cells; Rats; Reactive Oxygen Species | 2011 |
Clavulanic acid inhibits MPP⁺-induced ROS generation and subsequent loss of dopaminergic cells.
Topics: 1-Methyl-4-phenylpyridinium; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Caspase 9; Cell Line, Tumor; Clavulanic Acid; Cytochromes c; Dopamine; Humans; Membrane Potential, Mitochondrial; Mitochondria; Neurons; Neuroprotective Agents; Reactive Oxygen Species | 2012 |
Protective effects of Gynostemma pentaphyllum polysaccharides on PC12 cells impaired by MPP(+).
Topics: 1-Methyl-4-phenylpyridinium; Animals; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Caspase 9; Cell Survival; Cytochromes c; Gene Expression Regulation; Gynostemma; L-Lactate Dehydrogenase; Neurons; Neuroprotective Agents; Parkinson Disease; PC12 Cells; Poly(ADP-ribose) Polymerases; Polysaccharides; Proteolysis; Proto-Oncogene Proteins c-bcl-2; Rats | 2014 |
Bcl-2-associated athanogene 2 prevents the neurotoxicity of MPP+ via interaction with DJ-1.
Topics: 1-Methyl-4-phenylpyridinium; Cell Line, Tumor; Cytochromes c; Humans; Intracellular Signaling Peptides and Proteins; Membrane Potential, Mitochondrial; Molecular Chaperones; Neurons; Oncogene Proteins; Protein Binding; Protein Deglycase DJ-1; Reactive Oxygen Species | 2015 |
Neuroprotective effects of α-melanocyte-stimulating hormone against the neurotoxicity of 1-methyl-4-phenylpyridinium.
Topics: 1-Methyl-4-phenylpyridinium; Adenosine Triphosphate; alpha-MSH; Cell Line, Tumor; Cell Survival; Cytochromes c; Humans; Membrane Potential, Mitochondrial; Neuroblastoma; Neuroprotective Agents; Neurotoxicity Syndromes; Parkinson Disease; Reactive Oxygen Species | 2017 |
Overexpression of PGC-1α Influences Mitochondrial Signal Transduction of Dopaminergic Neurons.
Topics: 1-Methyl-4-phenylpyridinium; Adenosine Triphosphate; Adenoviridae; Cell Line, Tumor; Cell Survival; Cytochromes c; Dopaminergic Neurons; ERRalpha Estrogen-Related Receptor; Humans; Hydrogen Peroxide; Membrane Potential, Mitochondrial; Mitochondria; NF-E2-Related Factor 2; Oxidative Stress; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; PPAR gamma; Receptors, Estrogen; Signal Transduction; Subcellular Fractions | 2016 |
Protective effects of Ndfip1 on MPP(+)-induced apoptosis in MES23.5 cells and its underlying mechanisms.
Topics: 1-Methyl-4-phenylpyridinium; Animals; Apoptosis; bcl-2-Associated X Protein; Carrier Proteins; Caspase 3; Cell Line, Tumor; Cytochromes c; Cytosol; Dopamine Plasma Membrane Transport Proteins; Gene Expression Regulation; Green Fluorescent Proteins; Herbicides; Hybrid Cells; Membrane Proteins; Mice; Mitochondria; Proto-Oncogene Proteins c-bcl-2; Rats; RNA, Messenger; Time Factors; Transfection | 2015 |
Propofol protects against the neurotoxicity of 1‑methyl‑4‑phenylpyridinium.
Topics: 1-Methyl-4-phenylpyridinium; bcl-2-Associated X Protein; Caspase 3; Cell Death; Cell Line, Tumor; Cell Survival; Cytochromes c; Humans; Immunoblotting; L-Lactate Dehydrogenase; Mitochondria; Neuroprotective Agents; Neurotoxins; Nitric Oxide; Oxidative Stress; Propofol | 2016 |
Cx43 Mediates Resistance against MPP⁺-Induced Apoptosis in SH-SY5Y Neuroblastoma Cells via Modulating the Mitochondrial Apoptosis Pathway.
Topics: 1-Methyl-4-phenylpyridinium; Apoptosis; bcl-2-Associated X Protein; Blotting, Western; Caspase 3; Cell Line, Tumor; Cell Survival; Connexin 43; Cytochromes c; Herbicide Resistance; Herbicides; Humans; Mitochondria; Neuroblastoma; Poly(ADP-ribose) Polymerases; Proto-Oncogene Proteins c-bcl-2; RNA Interference; Signal Transduction | 2016 |
Nesfatin-1 protects dopaminergic neurons against MPP
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; Animals; Apoptosis; Calcium-Binding Proteins; Caspase 3; Cells, Cultured; Cytochromes c; Disease Models, Animal; DNA-Binding Proteins; Dopaminergic Neurons; MAP Kinase Signaling System; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Nerve Tissue Proteins; Nucleobindins; Parkinson Disease; Proto-Oncogene Proteins c-raf | 2017 |
P7C3 inhibits GSK3β activation to protect dopaminergic neurons against neurotoxin-induced cell death in vitro and in vivo.
Topics: 1-Methyl-4-phenylpyridinium; Animals; Antiparkinson Agents; bcl-2-Associated X Protein; Carbazoles; Cell Line, Tumor; Chimera; Cytochromes c; Dopaminergic Neurons; Gene Expression Regulation; Glycogen Synthase Kinase 3 beta; Membrane Potential, Mitochondrial; Mice; Mitochondria; Neuroglia; Neuroprotective Agents; Oxidative Stress; Rats; Reactive Oxygen Species; Signal Transduction; Substantia Nigra; Tumor Suppressor Protein p53 | 2017 |
Synphilin-1 has neuroprotective effects on MPP
Topics: 1-Methyl-4-phenylpyridinium; Apoptosis; Carrier Proteins; Caspase 3; Cell Survival; Cells, Cultured; Cytochromes c; Gene Knockdown Techniques; Humans; MPTP Poisoning; Nerve Tissue Proteins; Neuroprotective Agents; Poly(ADP-ribose) Polymerases; Reactive Oxygen Species; Transfection; Up-Regulation | 2019 |