Compounds > 1-methyl-4-phenylpyridinium
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1-methyl-4-phenylpyridinium and allopurinol

1-methyl-4-phenylpyridinium has been researched along with allopurinol in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (33.33)18.2507
2000's5 (55.56)29.6817
2010's1 (11.11)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Adams, JD; Cadenas, E; Klaidman, LK1
Desole, MS; Esposito, G; Fresu, GL; Miele, M; Migheli, R; Sircana, S; Zangani, D1
Adams, JD; Cadenas, E; Kim, SS; Klaidman, LK; Leung, AC1
Obata, T; Yamanaka, Y1
Kubota, S; Obata, T; Yamanaka, Y1
Alvarez, A; Fabregat, I; Fuentes, JM; González-Polo, RA; Soler, G1
An, L; Hong, JS; Li, G; Liu, B; Liu, Y; Qin, L; Zhang, W1
Obata, T1

Other Studies

9 other study(ies) available for 1-methyl-4-phenylpyridinium and allopurinol

ArticleYear
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
MPP+ redox cycling: a new mechanism involving hydride transfer.
    Annals of the New York Academy of Sciences, 1992, May-11, Volume: 648

    Topics: 1-Methyl-4-phenylpyridinium; Aldehyde Dehydrogenase; Dihydrolipoamide Dehydrogenase; Free Radicals; Kinetics; Mitochondria; Oxidation-Reduction; Xanthine Oxidase

1992
Effects of allopurinol on 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced neurochemical changes in the striatum and in the brainstem of the rat.
    Neuroscience letters, 1995, Jan-09, Volume: 183, Issue:3

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; Allopurinol; Animals; Ascorbic Acid; Brain Stem; Dopamine; Glutathione; Hypoxanthine; Hypoxanthines; Male; Neostriatum; Norepinephrine; Rats; Rats, Wistar; Uric Acid; Xanthines

1995
Redox cycling of MPP+: evidence for a new mechanism involving hydride transfer with xanthine oxidase, aldehyde dehydrogenase, and lipoamide dehydrogenase.
    Free radical biology & medicine, 1993, Volume: 15, Issue:2

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; Aldehyde Dehydrogenase; Dihydrolipoamide Dehydrogenase; Electron Spin Resonance Spectroscopy; Hydroxides; Hydroxyl Radical; NAD; Oxidation-Reduction; Photolysis; Superoxides; Ultraviolet Rays; Xanthine Oxidase

1993
Nitric oxide enhances MPP(+)-induced hydroxyl radical generation via depolarization activated nitric oxide synthase in rat striatum.
    Brain research, 2001, Jun-01, Volume: 902, Issue:2

    Topics: 1-Methyl-4-phenylpyridinium; Allopurinol; Animals; Dopamine; Enzyme Inhibitors; Extracellular Space; Herbicides; Hydroxybenzoates; Hydroxyl Radical; Iron; Iron Chelating Agents; Male; Membrane Potentials; Microdialysis; Neostriatum; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Oxidative Stress; Parkinson Disease; Potassium; Rats; Rats, Wistar

2001
Allopurinol suppresses para-nonylphenol and 1-methyl-4-phenylpyridinium ion (MPP(+))-induced hydroxyl radical generation in rat striatum.
    Neuroscience letters, 2001, Jun-22, Volume: 306, Issue:1-2

    Topics: 1-Methyl-4-phenylpyridinium; Allopurinol; Animals; Dose-Response Relationship, Drug; Drug Interactions; Free Radical Scavengers; Hazardous Substances; Hydroxyl Radical; Male; Microdialysis; Neostriatum; Nerve Degeneration; Parkinson Disease; Parkinson Disease, Secondary; Phenols; Rats; Rats, Wistar

2001
Vitamin E blocks early events induced by 1-methyl-4-phenylpyridinium (MPP+) in cerebellar granule cells.
    Journal of neurochemistry, 2003, Volume: 84, Issue:2

    Topics: 1-Methyl-4-phenylpyridinium; Allopurinol; Animals; Apoptosis; bcl-2-Associated X Protein; bcl-Associated Death Protein; Carrier Proteins; Cells, Cultured; Cerebellum; Cytochrome c Group; Enzyme Inhibitors; Female; Free Radical Scavengers; Glutathione; Male; Membrane Potentials; Mitochondria; Neurons; Phosphorylation; Protein Transport; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Wistar; Reactive Oxygen Species; Vitamin E; Xanthine Oxidase

2003
Dextromethorphan protects dopaminergic neurons against inflammation-mediated degeneration through inhibition of microglial activation.
    The Journal of pharmacology and experimental therapeutics, 2003, Volume: 305, Issue:1

    Topics: 1-Methyl-4-phenylpyridinium; Amyloid beta-Peptides; Animals; Cells, Cultured; Dextromethorphan; Drug Interactions; Inflammation; Lipopolysaccharides; Microglia; Nerve Degeneration; Neurons; Neuroprotective Agents; Rats; Rats, Inbred F344; Receptors, Dopamine; Superoxides; Xanthine; Xanthine Oxidase

2003
Allopurinol suppresses 2-bromoethylamine and 1-methyl-4-phenylpyridinium ion (MPP(+))-induced hydroxyl radical generation in rat striatum.
    Toxicology, 2006, Jan-20, Volume: 218, Issue:1

    Topics: 1-Methyl-4-phenylpyridinium; Allopurinol; Amine Oxidase (Copper-Containing); Animals; Corpus Striatum; Drug Synergism; Enzyme Inhibitors; Ethylamines; Hydroxyl Radical; Male; Microdialysis; Oxidative Stress; Rats; Rats, Wistar

2006