1-methyl-3-isobutylxanthine and verapamil

1-methyl-3-isobutylxanthine has been researched along with verapamil in 56 studies

Research

Studies (56)

TimeframeStudies, this research(%)All Research%
pre-199028 (50.00)18.7374
1990's19 (33.93)18.2507
2000's7 (12.50)29.6817
2010's2 (3.57)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET1
Conradi, R; Lee, PH; Shanmugasundaram, V1
Fijorek, K; Glinka, A; Mendyk, A; Polak, S; Wiśniowska, B1
Barnea, A; Magni, P1
Catterall, WA; Gartside, CL; Hauschka, SD; Morton, M; Scheuer, T; Sculptoreanu, A1
Blanco, I; Rodriguez, J; Rodriguez, R; Sabriá, J; Toledo, A1
Orekhova, NM1
Kaser, MR; Skouteris, GG1
Dziak, R; Schneeberger, G; Tatakis, DN1
Burrin, JM; Caldwell, G; Hart, GR1
Rice, CD; Weeks, BA1
Hanson, RL; Isaacson, CM1
Kato, H; Takata, Y1
Huff, JW; Reinach, PS1
Falotico, R; Fuller, BL; Moore, JB; Tolman, EL1
Dalaker, K; Prydz, H1
el Motal, SM; Pian-Smith, MC; Sharp, GW1
Gautvik, KM; Haug, E; Sletholt, K1
Harty, RF; Jain, DK; McGuigan, JE1
Hui, KK; Yu, JL1
Blanco, I; Brandner, R; Rodriguez, J; Rodriguez, R; Sabrià, J; Toledo, A1
Dasarathy, Y; Fanburg, BL1
Borst, S; Conolly, M1
Boyd, AE; Hill, RS; Rajan, AS1
Benishin, CG; Pang, PK; Zeng, YY1
Fujii, Y; Fujita, T; Fukase, M; Yamamoto, Y1
Furuki, Y; Hatada, Y; Maeyama, M; Miyamoto, E; Munemura, M; Sakoda, Y1
Kikuchi, M; Renold, AE; Sharp, GW; Siegel, EG; Wollheim, CB1
Gagnon, G; Regoli, D; Rioux, F2
Hammond, JM; Veldhuis, JD1
Gershengorn, MC1
Hirai, M; Komoriyama, K; Kouyama, H; Shima, S1
Kopf, GS; Lewis, CA; Vacquier, VD1
Bilezikjian, LM; Vale, WW1
Janjic, D; Wollheim, CB1
Goko, H; Kagawa, S; Matsuoka, A; Shimizu, S; Takashima, S1
Domboski, L; Krausz, Y; Phang, W; Sharp, GW1
Koshi, T1
Komiyama, H; Kozuka, H; Matsumoto, M; Miyahara, T; Miyanishi, A; Nagai, M; Takata, M; Takata, S; Xue-Ya, W; Yokoyama, K1
Fox, DA; Medrano, CJ1
Columbo, M; Horowitz, EM; Kagey-Sobotka, A; Lichtenstein, LM; McKenzie-White, J1
Komitowska, J; Raue, F; Zink-Lorenz, A1
Abe, M; Arai, J; Asami, K; Kusunoki, S; Miyashita, Y; Moriya, T1
Kato, S; Takehara, K; Takeuchi, K; Yagi, K1
Kato, S; Takeuchi, K; Ukawa, H; Yagi, K1
Kildalsen, H; Sager, G; Schultz, C; Vaskinn, S1
Wong, KK1
Dedos, SG; Fugo, H1
De Proft, R; Dejonghe, S; Gorus, F; Ling, Z; Pipeleers, D; Schuit, F; Winnock, F1
Aihara, E; Aoi, M; Nakashima, M; Takeuchi, K1
Cia, D; Duboc, A; Forster, V; Gong, J; Jellali, A; Picaud, S; Sahel, JA; Tessier, LH; Vallazza-Deschamps, G1
Abdel-Wahab, YH; Ali, L; Flatt, PR; Hannan, JM; Marenah, L; Rokeya, B1
Daenas, C; Gourgoulianis, KI; Hatziefthimiou, AA; Molyvdas, PA1
Bulaeva, SV; Chuchkanov, FA; Maimistova, AA; Muravyov, AV; Yakusevich, VV; Zaitsev, LG1
Kaneda, T; Konno, Y; Nakajyo, S; Shimizu, K; Urakawa, N1

Reviews

1 review(s) available for 1-methyl-3-isobutylxanthine and verapamil

ArticleYear
Thyrotropin releasing hormone. A review of the mechanisms of acute stimulation of pituitary hormone release.
    Molecular and cellular biochemistry, 1982, Jun-25, Volume: 45, Issue:3

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Calcium; Cells, Cultured; Chlortetracycline; Cyclic AMP; Guanylyl Imidodiphosphate; Ion Channels; Pituitary Gland; Pituitary Neoplasms; Potassium; Prolactin; Protein Kinases; Sodium Fluoride; Thyrotropin; Thyrotropin-Releasing Hormone; Verapamil

1982

Other Studies

55 other study(ies) available for 1-methyl-3-isobutylxanthine and verapamil

ArticleYear
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium

1985
Development of an in silico model for human skin permeation based on a Franz cell skin permeability assay.
    Bioorganic & medicinal chemistry letters, 2010, Jan-01, Volume: 20, Issue:1

    Topics: 1-Methyl-3-isobutylxanthine; Cell Line; Cell Membrane Permeability; Humans; Models, Biological; Quantitative Structure-Activity Relationship; Skin Absorption

2010
Predictive model for L-type channel inhibition: multichannel block in QT prolongation risk assessment.
    Journal of applied toxicology : JAT, 2012, Volume: 32, Issue:10

    Topics: Artificial Intelligence; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Line; Computational Biology; Computer Simulation; Drugs, Investigational; Ether-A-Go-Go Potassium Channels; Expert Systems; Heart Rate; Humans; Models, Biological; Myocytes, Cardiac; NAV1.5 Voltage-Gated Sodium Channel; Potassium Channel Blockers; Quantitative Structure-Activity Relationship; Risk Assessment; Shaker Superfamily of Potassium Channels; Torsades de Pointes; Voltage-Gated Sodium Channel Blockers

2012
Forskolin and phorbol ester stimulation of neuropeptide Y (NPY) production and secretion by aggregating fetal brain cells in culture: evidence for regulation of NPY biosynthesis at transcriptional and posttranscriptional levels.
    Endocrinology, 1992, Volume: 130, Issue:2

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Brain; Cell Aggregation; Cells, Cultured; Colforsin; Cycloheximide; Dactinomycin; Dose-Response Relationship, Drug; Fetus; Hypothalamus; Kinetics; Neuropeptide Y; Olfactory Bulb; Protein Biosynthesis; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate; Transcription, Genetic; Verapamil

1992
Tetrodotoxin-insensitive sodium channels in a cardiac cell line from a transgenic mouse.
    The American journal of physiology, 1992, Volume: 262, Issue:3 Pt 1

    Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Cell Line; Cell Membrane; Cyclic AMP; Electric Conductivity; Isoproterenol; Kinetics; Membrane Potentials; Mice; Mice, Transgenic; Myocardium; Protein Kinases; Sodium Channels; Tetrodotoxin; Verapamil

1992
A comparative study of histamine and K+ effects on (Ca(2+)-Mg2+)-ATPase activity in synaptosomes.
    Biochemical pharmacology, 1991, Jun-15, Volume: 41, Issue:12

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Ca(2+) Mg(2+)-ATPase; Calcium Chloride; Calcium-Transporting ATPases; Cell Membrane; Choline; Diltiazem; Dose-Response Relationship, Drug; Histamine; Potassium; Pyrilamine; Ranitidine; Rats; Sodium; Synapses; Synaptosomes; Verapamil

1991
Proliferative and synthetic activity of cells from reoccluded distal anastomosis and pharmacological therapy of this postoperative complication.
    Agents and actions, 1991, Volume: 32, Issue:1-2

    Topics: 1-Methyl-3-isobutylxanthine; Anastomosis, Surgical; Aorta; Arteriosclerosis; Cell Division; Colforsin; Collagen; Femoral Artery; Glycosaminoglycans; Graft Occlusion, Vascular; Humans; Verapamil

1991
Prostaglandins E2 and F2a mediate the increase in c-myc expression induced by EGF in primary rat hepatocyte cultures.
    Biochemical and biophysical research communications, 1991, Aug-15, Volume: 178, Issue:3

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Blotting, Northern; Cell Division; Dinoprost; Dinoprostone; DNA Replication; Epidermal Growth Factor; Gene Expression; Genes, myc; Kinetics; Liver; Male; Proto-Oncogene Proteins c-myc; Rats; Rats, Inbred Strains; RNA; Verapamil

1991
Recombinant interleukin-1 (IL-1) stimulates prostaglandin E2 production by osteoblastic cells: role of calcium, calmodulin, and cAMP.
    Lymphokine and cytokine research, 1991, Volume: 10, Issue:1-2

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Calcium; Calmodulin; Cells, Cultured; Cyclic AMP; Dinoprostone; Interleukin-1; Osteoblasts; Parathyroid Hormone; Rats; Recombinant Proteins; Sulfonamides; Verapamil

1991
Intracellular mechanisms involved in the stimulation of growth hormone release from rat anterior pituitary cells by Russell's viper venom.
    The Journal of endocrinology, 1990, Volume: 127, Issue:1

    Topics: 1-Methyl-3-isobutylxanthine; Aminoquinolines; Animals; Calcium; Cells, Cultured; Culture Media; Cyclic AMP; Growth Hormone; Pituitary Gland, Anterior; Rats; Tetradecanoylphorbol Acetate; Verapamil; Viper Venoms

1990
Tributyltin stimulates reactive oxygen formation in toadfish macrophages.
    Developmental and comparative immunology, 1991,Fall, Volume: 15, Issue:4

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Benzoates; Benzoic Acid; Calcimycin; Calcium; Calcium Channels; Fishes; Free Radical Scavengers; Free Radicals; Indomethacin; Luminescent Measurements; Macrophage Activation; Macrophages; Masoprocol; Oxygen; Superoxide Dismutase; Tetradecanoylphorbol Acetate; Trialkyltin Compounds; Trifluoperazine; Verapamil

1991
Stimulation of insulin secretion from isolated rat islets by SaRI 59-801. Relation to cAMP concentration and Ca2+ uptake.
    Diabetes, 1985, Volume: 34, Issue:7

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Bucladesine; Calcium; Colforsin; Cyclic AMP; Diterpenes; Hypoglycemic Agents; Insulin; Insulin Secretion; Islets of Langerhans; Isoxazoles; Male; Nifedipine; Oxazoles; Rats; Rats, Inbred Strains; Theophylline; Tolbutamide; Verapamil

1985
Effects of Ca antagonists on the norepinephrine release and contractile responses of isolated canine saphenous veins to high KCl.
    Japanese journal of pharmacology, 1985, Volume: 37, Issue:4

    Topics: 1-Methyl-3-isobutylxanthine; Anesthetics, Local; Animals; Calcium Channel Blockers; Diltiazem; Dogs; Female; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nicardipine; Nifedipine; Norepinephrine; Phentolamine; Potassium Chloride; Saphenous Vein; Verapamil

1985
Mechanism of inhibition of net ion transport across frog corneal epithelium by calcium channel antagonists.
    The Journal of membrane biology, 1985, Volume: 85, Issue:3

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Bepridil; Calcimycin; Calcium Channel Blockers; Cornea; Cyclic AMP; Diltiazem; Electric Conductivity; Epithelium; In Vitro Techniques; Ion Channels; Isoproterenol; Kinetics; Pyrrolidines; Rana catesbeiana; Sodium-Potassium-Exchanging ATPase; Verapamil

1985
Inhibition of rabbit platelet phosphodiesterase activity and aggregation by calcium channel blockers.
    Thrombosis research, 1985, Nov-01, Volume: 40, Issue:3

    Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Adenosine Diphosphate; Animals; Blood Platelets; Calcium Channel Blockers; Cytosol; Diltiazem; Kinetics; Nifedipine; Platelet Aggregation; Rabbits; Structure-Activity Relationship; Verapamil

1985
Effect of some drugs on thromboplastin activity in mouse trophoblast cells in vitro and in vivo.
    Biochemical pharmacology, 1986, Oct-15, Volume: 35, Issue:20

    Topics: 1-Methyl-3-isobutylxanthine; Adenine; Adenosine; Animals; Calcium Channel Blockers; Dinoprostone; Felodipine; Female; Gallic Acid; Methylation; Mice; Monensin; Nifedipine; Nitrendipine; Pregnancy; Prostaglandins E; Thromboplastin; Trophoblasts; Tubercidin; Verapamil

1986
Effects of tetracaine on insulin release and calcium handling by rat pancreatic islets.
    The American journal of physiology, 1987, Volume: 252, Issue:6 Pt 1

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Calcium; Drug Synergism; Gallic Acid; Glucose; Insulin; Islets of Langerhans; Male; Rats; Rats, Inbred Strains; Tetracaine; Verapamil

1987
On the involvement of cyclic AMP and extracellular Ca2+ in the regulation of hormone release from rat pituitary tumour (GH3) cells in culture.
    Bioscience reports, 1987, Volume: 7, Issue:2

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Bucladesine; Calcimycin; Calcium; Cell Line; Cobalt; Cyclic AMP; Egtazic Acid; Extracellular Space; Growth Hormone; Pituitary Neoplasms; Prolactin; Rats; Thyrotropin-Releasing Hormone; Trifluoperazine; Verapamil

1987
Mechanisms of vasoactive intestinal peptide release in short-term culture of vasoactive intestinal peptide-producing tumor.
    Gastroenterology, 1988, Volume: 94, Issue:2

    Topics: 1-Methyl-3-isobutylxanthine; Adenoma, Islet Cell; Calcimycin; Calcium; Cells, Cultured; Cyclic AMP; Egtazic Acid; Female; Humans; Immunohistochemistry; Leucine; Middle Aged; Pancreatic Neoplasms; Radioimmunoassay; Vasoactive Intestinal Peptide; Verapamil; Vipoma

1988
The effects of calcium channel blockers on isoproterenol induced cyclic adenosine 3',5'-monophosphate generation in intact human lymphocytes.
    Life sciences, 1988, Volume: 42, Issue:20

    Topics: 1-Methyl-3-isobutylxanthine; Calcium Channel Blockers; Cyclic AMP; Diltiazem; Drug Synergism; Humans; Isoproterenol; Kinetics; Lanthanum; Lymphocytes; Nifedipine; Phenothiazines; Verapamil

1988
Histamine stimulated synaptosomal Ca2+ uptake through activation of calcium channels.
    Biochemical and biophysical research communications, 1988, Jun-30, Volume: 153, Issue:3

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Brain; Bucladesine; Calcium; Cinnarizine; Cyclic AMP; Diltiazem; Flunarizine; Histamine; Ion Channels; Nifedipine; Rats; Synaptosomes; Verapamil

1988
Elevation of angiotensin converting enzyme by 3-isobutyl-1-methylxanthine in cultured endothelial cells: a possible role for calmodulin.
    Journal of cellular physiology, 1988, Volume: 137, Issue:1

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Calmodulin; Cattle; Cells, Cultured; Cyclic AMP; Cycloheximide; Dose-Response Relationship, Drug; Egtazic Acid; Endothelium, Vascular; Imidazoles; Indomethacin; Peptidyl-Dipeptidase A; Propranolol; Theophylline; Trifluoperazine; Verapamil; Xanthines

1988
Calcium dependence of beta-adrenoceptor mediated cyclic AMP accumulation in human lymphocytes.
    Life sciences, 1988, Volume: 43, Issue:13

    Topics: 1-Methyl-3-isobutylxanthine; Calcimycin; Calcium; Cells, Cultured; Cyclic AMP; Edetic Acid; Humans; Isoproterenol; Kinetics; Lanthanum; Lymphocytes; Nifedipine; Receptors, Adrenergic, beta; Verapamil

1988
Effect of rise in cAMP levels on Ca2+ influx through voltage-dependent Ca2+ channels in HIT cells. Second-messenger synarchy in beta-cells.
    Diabetes, 1989, Volume: 38, Issue:7

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Benzofurans; Calcium; Calcium Channels; Cell Line; Cells, Cultured; Colforsin; Cyclic AMP; Electrophysiology; Fura-2; Glucagon; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Second Messenger Systems; Verapamil

1989
Guanine nucleotide binding proteins may modulate gating of calcium channels in vascular smooth muscle. I. Studies with fluoride.
    The Journal of pharmacology and experimental therapeutics, 1989, Volume: 250, Issue:1

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Arginine Vasopressin; Arteries; Bucladesine; Calcium; Calcium Channels; Colforsin; Cyclic AMP; Cyclic GMP; GTP-Binding Proteins; In Vitro Techniques; Inositol Phosphates; Kinetics; Male; Muscle, Smooth, Vascular; Nifedipine; Potassium Chloride; Rats; Rats, Inbred Strains; Sodium Fluoride; Vasoconstriction; Verapamil

1989
The effects of human parathyroid hormone-related peptide on cytosolic free calcium and cAMP production in opossum kidney cell.
    Bone and mineral, 1989, Volume: 7, Issue:3

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Bucladesine; Calcium; Cell Line; Cyclic AMP; Cytosol; Diltiazem; Kidney; Neoplasm Proteins; Opossums; Parathyroid Hormone; Parathyroid Hormone-Related Protein; Peptide Fragments; Proteins; Teriparatide; Verapamil

1989
Involvement of calcium in the release of immunoreactive beta-endorphin-like peptide from dispersed cells of the neurointermediate lobe of the rat pituitary gland.
    Japanese journal of pharmacology, 1985, Volume: 37, Issue:3

    Topics: 1-Methyl-3-isobutylxanthine; Animals; beta-Endorphin; Bucladesine; Calcimycin; Calcium; Cholera Toxin; Colforsin; Cyclic AMP; Diterpenes; Endorphins; In Vitro Techniques; Isoproterenol; Pituitary Gland; Rats; Theophylline; Verapamil

1985
Dependency of cyclic AMP-induced insulin release on intra- and extracellular calcium in rat islets of Langerhans.
    The Journal of clinical investigation, 1980, Volume: 65, Issue:2

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Calcium; Culture Techniques; Cyclic AMP; Cytosol; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Male; Rats; Verapamil

1980
Studies on the mechanism of action of glucagon in strips of rabbit renal artery.
    British journal of pharmacology, 1980, Volume: 69, Issue:3

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Calcium; Cyclic AMP; Female; Glucagon; In Vitro Techniques; Indomethacin; Male; Papaverine; Phosphodiesterase Inhibitors; Proadifen; Rabbits; Renal Artery; Theophylline; Vasodilator Agents; Verapamil

1980
Studies on the mechanism of action of various vasodilators.
    British journal of pharmacology, 1980, Volume: 70, Issue:2

    Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Animals; Calcium; Cyclic AMP; In Vitro Techniques; Isoproterenol; Muscle, Smooth, Vascular; Nitroglycerin; Papaverine; Rabbits; Vasodilator Agents; Verapamil

1980
Role of calcium in the modulation of ornithine decarboxylase activity in isolated pig granulosa cells in vitro.
    The Biochemical journal, 1981, Jun-15, Volume: 196, Issue:3

    Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Calcium; Carboxy-Lyases; Cyclic AMP; Female; Follicle Stimulating Hormone; Granulosa Cells; In Vitro Techniques; Luteinizing Hormone; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Swine; Verapamil

1981
beta-Adrenergic stimulation of the adenosine 3',5'-monophosphate system regulated by cholinergic stimuli in the prostate.
    Biochemical pharmacology, 1983, Feb-01, Volume: 32, Issue:3

    Topics: 1-Methyl-3-isobutylxanthine; Acetylcholine; Animals; Atropine; Calcimycin; Calcium; Cell Membrane; Cyclic AMP; Hexamethonium; Hexamethonium Compounds; Isoproterenol; Male; Parasympathetic Nervous System; Prostate; Rats; Receptors, Adrenergic; Receptors, Adrenergic, beta; Tetracaine; Theophylline; Verapamil

1983
Methylxanthines stimulate calcium transport and inhibit cyclic nucleotide phosphodiesterases in abalone sperm.
    Developmental biology, 1983, Volume: 99, Issue:1

    Topics: 1-Methyl-3-isobutylxanthine; Acrosome; Animals; Biological Transport; Calcium; Cyclic AMP; Male; Mollusca; Phosphodiesterase Inhibitors; Spermatozoa; Theophylline; Verapamil

1983
Stimulation of adenosine 3',5'-monophosphate production by growth hormone-releasing factor and its inhibition by somatostatin in anterior pituitary cells in vitro.
    Endocrinology, 1983, Volume: 113, Issue:5

    Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Cyclic AMP; Growth Hormone; Growth Hormone-Releasing Hormone; Male; Pimozide; Pituitary Gland, Anterior; Rats; Rats, Inbred Strains; Somatostatin; Time Factors; Verapamil

1983
Cobalt inhibition of insulin release: evidence for an action not related to Ca2+ uptake.
    The American journal of physiology, 1984, Volume: 246, Issue:1 Pt 1

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Biological Transport, Active; Calcium; Cells, Cultured; Cobalt; Cyclic AMP; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Male; Potassium; Rats; Rats, Inbred Strains; Verapamil

1984
Effects of verapamil on lipolysis due to dibutyryl cyclic AMP.
    The Biochemical journal, 1984, May-15, Volume: 220, Issue:1

    Topics: 1-Methyl-3-isobutylxanthine; Adipose Tissue; Animals; Bucladesine; Cyclic AMP; Dose-Response Relationship, Drug; Epinephrine; In Vitro Techniques; Lipolysis; Male; Rats; Rats, Inbred Strains; Verapamil

1984
Mechanisms of synergism between glucose and cAMP on stimulation of insulin release.
    The American journal of physiology, 1984, Volume: 247, Issue:6 Pt 1

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Biomechanical Phenomena; Calcium; Carbachol; Choline; Colforsin; Cyclic AMP; Diterpenes; Drug Synergism; Glucose; Insulin; Ion Exchange; Islets of Langerhans; Isotonic Solutions; Male; Ouabain; Potassium Chloride; Rats; Rats, Inbred Strains; Ringer's Solution; Sodium; Stimulation, Chemical; Verapamil

1984
[Abnormal secretory response to verapamil of pancreatic B cells of neonatal rats maintained in high glucose].
    Nihon Naibunpi Gakkai zasshi, 1993, Oct-20, Volume: 69, Issue:9

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Animals, Newborn; Calcium Channel Blockers; Cells, Cultured; Culture Media; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Rats; Rats, Sprague-Dawley; Verapamil

1993
Effects of lead on osteoclast-like cell formation in mouse bone marrow cell cultures.
    Calcified tissue international, 1994, Volume: 54, Issue:2

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Bone Marrow; Bone Marrow Cells; Calcimycin; Calcitonin; Cell Differentiation; Cell Nucleus; Cells, Cultured; Cyclic AMP; Dibenz(b,f)(1,4)oxazepine-10(11H)-carboxylic acid, 8-chloro-, 2-acetylhydrazide; Dideoxyadenosine; Dinoprostone; Indomethacin; Lead; Male; Mice; Mice, Inbred Strains; Osteoclasts; Parathyroid Hormone; Verapamil

1994
Oxygen consumption in the rat outer and inner retina: light- and pharmacologically-induced inhibition.
    Experimental eye research, 1995, Volume: 61, Issue:3

    Topics: 1-Methyl-3-isobutylxanthine; Adaptation, Ocular; Aminobutyrates; Animals; Cobalt; Cytochrome a Group; Dose-Response Relationship, Drug; Female; Kynurenic Acid; Lead; Light; Magnesium; Oxidation-Reduction; Oxygen Consumption; Rats; Rats, Inbred Strains; Retina; Spectrophotometry; Verapamil

1995
Pharmacologic control of histamine release from human basophils induced by platelet-activating factor.
    International archives of allergy and immunology, 1993, Volume: 102, Issue:4

    Topics: 1-Methyl-3-isobutylxanthine; Basophils; Cyclic AMP; Enzyme Inhibitors; Histamine Release; Humans; Pertussis Toxin; Platelet Activating Factor; Verapamil; Virulence Factors, Bordetella

1993
Norepinephrine induced calcitonin secretion in rat medullary thyroid carcinoma 6-23 cells: interaction between intracellular calcium and cAMP.
    Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association, 1996, Volume: 104, Issue:1

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Calcitonin; Calcium; Calcium Channel Blockers; Carcinoma, Medullary; Cell Line; Cyclic AMP; Cytosol; Dose-Response Relationship, Drug; Egtazic Acid; Kinetics; Norepinephrine; Phentolamine; Phenylisopropyladenosine; Rats; Thyroid Neoplasms; Tumor Cells, Cultured; Verapamil

1996
Light-sensitive response in melanophores of Xenopus laevis: I. Spectral characteristics of melanophore response in isolated tail fin of Xenopus tadpole.
    The Journal of experimental zoology, 1996, Sep-01, Volume: 276, Issue:1

    Topics: 1-Methyl-3-isobutylxanthine; 4-Aminopyridine; Amphibians; Animals; Calcium; Calcium Channel Blockers; Cyclic CMP; Cyclic GMP; Enzyme Inhibitors; Gallic Acid; Ionophores; Light; Macrolides; Melanophores; Membrane Potentials; Ouabain; Phosphodiesterase Inhibitors; Potassium Channel Blockers; Retinal Rod Photoreceptor Cells; Skin Pigmentation; Sodium-Potassium-Exchanging ATPase; Tail; Verapamil; Xenopus laevis

1996
PACAPs stimulate duodenal bicarbonate secretion at PACAP receptors in the rat.
    The American journal of physiology, 1997, Volume: 272, Issue:3 Pt 1

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Atropine; Bicarbonates; Cyclic AMP; Dinoprostone; Duodenum; Gastric Mucosa; Indomethacin; Male; Neuropeptides; Pituitary Adenylate Cyclase-Activating Polypeptide; Rats; Rats, Sprague-Dawley; Receptors, Cell Surface; Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide; Receptors, Pituitary Hormone; Secretory Rate; Vagotomy; Vagus Nerve; Vasoactive Intestinal Peptide; Verapamil

1997
Roles of prostaglandin E-receptor subtypes in gastric and duodenal bicarbonate secretion in rats.
    Gastroenterology, 1997, Volume: 113, Issue:5

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Bicarbonates; Calcium; Dinoprostone; Duodenum; Gastric Mucosa; Hydrazines; Male; Oxazepines; Prostaglandins E; Rats; Rats, Sprague-Dawley; Receptors, Prostaglandin E; Verapamil

1997
Cyclic AMP stimulates the cyclic GMP egression pump in human erythrocytes: effects of probenecid, verapamil, progesterone, theophylline, IBMX, forskolin, and cyclic AMP on cyclic GMP uptake and association to inside-out vesicles.
    Biochemistry, 1998, Jan-27, Volume: 37, Issue:4

    Topics: 1-Methyl-3-isobutylxanthine; Biological Transport, Active; Colforsin; Cyclic AMP; Cyclic GMP; Dimethyl Sulfoxide; Erythrocyte Membrane; Humans; Ion Pumps; Probenecid; Progesterone; Theophylline; Verapamil

1998
Drug induced contraction and relaxation in mouse isolated aorta.
    Artery, 1997, Volume: 22, Issue:4

    Topics: 1-Methyl-3-isobutylxanthine; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Aorta; Bethanechol; Clonidine; Electric Stimulation; In Vitro Techniques; Male; Mice; Mice, Inbred ICR; Muscarinic Agonists; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Neuromuscular Depolarizing Agents; Nitroprusside; Norepinephrine; Phosphodiesterase Inhibitors; Potassium Chloride; Prazosin; Serotonin; Vasoconstrictor Agents; Vasodilator Agents; Verapamil

1997
Interactions between Ca2+ and cAMP in ecdysteroid secretion from the prothoracic glands of Bombyx mori.
    Molecular and cellular endocrinology, 1999, Aug-20, Volume: 154, Issue:1-2

    Topics: 1-Methyl-3-isobutylxanthine; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Bombyx; Bucladesine; Calcimycin; Calcium; Colforsin; Cyclic AMP; Drug Interactions; Ecdysterone; Enzyme Inhibitors; Phosphodiesterase Inhibitors; Second Messenger Systems; Signal Transduction; Thionucleotides; Verapamil

1999
Correlation between GABA release from rat islet beta-cells and their metabolic state.
    American journal of physiology. Endocrinology and metabolism, 2002, Volume: 282, Issue:4

    Topics: 1-Methyl-3-isobutylxanthine; 2,4-Dinitrophenol; Adenosine Triphosphate; Animals; Calcium; Culture Media, Conditioned; Cycloheximide; Diazoxide; gamma-Aminobutyric Acid; Glucagon; Glucagon-Like Peptide 1; Glucose; Glutamate Decarboxylase; Glyburide; Islets of Langerhans; Male; Mannoheptulose; Oxidation-Reduction; Peptide Fragments; Protein Precursors; Rats; Rats, Wistar; Verapamil

2002
Participation of prostaglandin E receptor EP4 subtype in duodenal bicarbonate secretion in rats.
    American journal of physiology. Gastrointestinal and liver physiology, 2004, Volume: 287, Issue:1

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Bicarbonates; Capsaicin; Dinoprostone; Drug Combinations; Duodenum; Hydrochloric Acid; Male; Methyl Ethers; Naphthalenes; Phenylbutyrates; Rats; Rats, Sprague-Dawley; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP4 Subtype; Verapamil

2004
Excessive activation of cyclic nucleotide-gated channels contributes to neuronal degeneration of photoreceptors.
    The European journal of neuroscience, 2005, Volume: 22, Issue:5

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Animals, Newborn; Blotting, Western; Cadmium Chloride; Calcium Channel Blockers; Cell Death; Cells, Cultured; Cyclic Nucleotide-Gated Cation Channels; Diltiazem; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; In Situ Nick-End Labeling; In Vitro Techniques; Ion Channels; Mice; Mice, Mutant Strains; Nerve Degeneration; Neuroglia; Phosphodiesterase Inhibitors; Photoreceptor Cells; Purinones; Rats; Rats, Wistar; Swine; Verapamil

2005
Ocimum sanctum leaf extracts stimulate insulin secretion from perfused pancreas, isolated islets and clonal pancreatic beta-cells.
    The Journal of endocrinology, 2006, Volume: 189, Issue:1

    Topics: 1-Methyl-3-isobutylxanthine; Acetates; Animals; Butanols; Cell Line; Diazoxide; Ethanol; Glucose; Insulin; Insulin Secretion; Insulin-Secreting Cells; Islets of Langerhans; Ocimum; Pancreas; Perfusion; Plant Extracts; Plant Leaves; Potassium Chloride; Rats; Rats, Long-Evans; Tissue Culture Techniques; Tolbutamide; Verapamil

2006
Azithromycin has a direct relaxant effect on precontracted airway smooth muscle.
    European journal of pharmacology, 2006, Dec-28, Volume: 553, Issue:1-3

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Anti-Bacterial Agents; Atropine; Azithromycin; Bronchodilator Agents; Calcium; Calcium Channel Blockers; Calcium-Transporting ATPases; Carbachol; Enzyme Inhibitors; Epithelium; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Muscarinic Agonists; Muscle Contraction; Muscle Relaxation; Muscle Tonus; Muscle, Smooth; Ouabain; Phosphodiesterase Inhibitors; Potassium Chloride; Protein Serine-Threonine Kinases; Rabbits; rho-Associated Kinases; Trachea; Verapamil

2006
Hemorheological efficiency of drugs, targeting on intracellular phosphodiesterase activity: in vitro study.
    Clinical hemorheology and microcirculation, 2007, Volume: 36, Issue:4

    Topics: 1-Methyl-3-isobutylxanthine; Adult; Blood Viscosity; Caffeine; Calcimycin; Calcium; Egtazic Acid; Erythrocyte Aggregation; Hemorheology; Humans; Male; Nifedipine; Papaverine; Pentoxifylline; Phosphodiesterase Inhibitors; Verapamil; Vinca Alkaloids

2007
Ibudilast-induced decreases in cytosolic Ca(2+) level and contraction in rat aorta.
    Journal of pharmacological sciences, 2007, Volume: 104, Issue:4

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Aorta, Thoracic; Calcium; Cyclic AMP; Cyclic GMP; Cytosol; Dose-Response Relationship, Drug; Male; Muscle Contraction; Muscle Tonus; Muscle, Smooth, Vascular; Phenylephrine; Phosphodiesterase Inhibitors; Potassium; Pyridines; Rats; Rats, Wistar; Vasodilator Agents; Verapamil

2007