1-methyl-3-isobutylxanthine has been researched along with tetradecanoylphorbol acetate in 315 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 95 (30.16) | 18.7374 |
| 1990's | 190 (60.32) | 18.2507 |
| 2000's | 28 (8.89) | 29.6817 |
| 2010's | 2 (0.63) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Sanders, MM; Skoufos, E | 1 |
| Claycomb, WC; Springhorn, JP | 2 |
| Crook, RB; Yabu, JM | 1 |
| Koch, B; Lutz-Bucher, B | 1 |
| Brubaker, PL; Lévesque, L; Sun, AM | 1 |
| Barnea, A; Magni, P | 1 |
| Abdel-Malek, Z; Krug, K; Nordlund, JJ; Pallas, J; Swope, VB | 1 |
| Karnovsky, MJ; Ottlinger, ME; Pukac, LA | 1 |
| Decker, GL; Epstein, PN; Means, AR; Ribar, TJ; Yaney, G | 1 |
| Richter, J | 1 |
| Albertini, DF; Wickramasinghe, D | 1 |
| Copolov, DL; Huang, W; Lee, D; Lim, AT; Yang, Z | 1 |
| Arneson-Rotert, LJ; Hoffman, JM; Liewer, SA; Toews, ML | 1 |
| Aucouturier, S; Bernard, C; Chayvialle, JA; Cuber, JC | 1 |
| Bressler, JP; Brightman, MW; Tao-Cheng, JH | 1 |
| Rivedal, E; Roseng, LE; Sanner, T | 1 |
| Johnson, RA; Toews, ML | 1 |
| Nishikawa, T; Tamura, Y; Yoshida, A; Yoshida, S | 1 |
| Johnson, AL; Tilly, JL | 4 |
| Zawalich, KC; Zawalich, WS | 1 |
| D'Ambra, R; Efrat, S; Fleischer, N; Starr, RG; Surana, M | 1 |
| Iwashita, S; Mitsui, K; Senshu-Miyaike, M; Shoji-Kasai, Y | 1 |
| Brubaker, PL; Drucker, DJ; Greenberg, GR | 1 |
| Holsboer, F; Spengler, DH; Van, LP | 1 |
| Boxer, LA; Ljungman, AG; Marks, RM; Morganroth, ML; Riva, CM; Schoeneich, SO; Todd, RF; Ward, PA | 1 |
| Medrano, EE; Nordlund, JJ | 1 |
| Horie, S; Ishii, H; Kazama, M; Kizaki, K; Uchiyama, H | 1 |
| Gullberg, U; Lantz, M; Lindvall, L; Olsson, I | 1 |
| Davidson, JS; Macrae, MB; Millar, RP; van der Merwe, PA | 1 |
| Loessberg, PA; Muallem, S; Sachs, G; Zhao, H | 1 |
| Brammer, MJ; Campbell, IC; Xiang, JZ | 1 |
| Fuller, BB; Hoganson, GE; Niekrasz, I | 1 |
| García-Sáinz, JA; Hernández-Sotomayor, SM; Macías-Silva, M; Malbon, CC | 1 |
| Malamed, S; Perez, FM; Scanes, CG | 1 |
| Hemmings, BA; Jans, DA | 1 |
| Davidson, JS; Millar, RP; van der Merwe, PA; Wakefield, IK | 1 |
| Agwu, DE; McCall, CE; McPhail, LC | 1 |
| Lipsky, PE; Minakuchi, R; Wacholtz, MC | 1 |
| Bos, MP; Herrmann-Erlee, MP; van Leeuwen, JP | 1 |
| Taub, M; Wang, Y | 1 |
| Lachowicz, L; Turski, WA | 1 |
| Defeo-Jones, D; Haskell, KM; Jones, RE; McAvoy, EM; Oliff, A; Vuocolo, GA; Wegrzyn, RJ | 1 |
| Cagliero, E; Lorenzi, M; Maiello, M; Roth, T; Roy, S | 1 |
| Brooks, JW; Chedid, M; Mizel, SB; Yoza, BK | 1 |
| Grenfell, S; Ray, K; Rollins, P; Sadler, H; Smithers, N; Solari, R; Thompson, N; Witham, S | 1 |
| Orson, FM; Patke, CL; Shearer, WT | 1 |
| Burrin, JM; Caldwell, G; Hart, GR | 1 |
| Khademazad, M; Loessberg, P; Muallem, S; Whisenant, N; Zhang, BX | 1 |
| Jansen, PL; Ottenhoff, R; Oude Elferink, RP; Roelofsen, H | 1 |
| Burbach, JP; Sutanto, W; Verbeeck, MA | 1 |
| Anderson, RJ; Breckon, R; Colston, D | 1 |
| Doppler, W; Egle, A; Grunicke, HH; Hofmann, J; Maly, K; Uberall, F | 1 |
| Alexandre, H; Mulnard, J; Tsukitani, Y; Van Cauwenberge, A | 1 |
| Fabbro, D; Knesel, J; Nagamine, Y; Ziegler, A | 1 |
| Abraham, RT; Abu-Ghazaleh, RI; Gleich, GJ; Kita, H | 1 |
| Haneda, M; Horide, N; Kajiwara, N; Kikkawa, R; Koya, D; Maeda, S; Shigeta, Y; Togawa, M | 1 |
| Asa, SL; Brubaker, PL; Drucker, DJ; Greenberg, GR | 1 |
| Folkesson, R; Monstein, HJ | 1 |
| Ganz, MB; Vignery, A; Wang, F | 1 |
| Jakubowiak, A; Janecki, A; Steinberger, A | 1 |
| Cho, HS; Katzenellenbogen, BS; NG, PA | 1 |
| Rice, CD; Weeks, BA | 1 |
| Michael, AE; Webley, GE | 1 |
| Donoghue, DJ; Scanes, CG | 1 |
| Carroll, JM; Evinger, MJ; Goodman, HM; Joh, TH | 1 |
| Kato, Y; Tanigawa, K; Tsuchiyama, S | 1 |
| Field, JB; Nielsen, TB; Rani, CS; Tanabe, A | 1 |
| Cronin, MJ; Perkins, SN; Summers, ST | 1 |
| Scott, RE; Wier, ML | 1 |
| Eckhardt, L; Imamura, K; Kimura, T; Schulz, I | 1 |
| Duray, P; Ghosh, S; Halaban, R; Kirkwood, JM; Lerner, AB | 1 |
| Danoff, A; Fleischer, N; Pasmantier, R; Schubart, UK | 1 |
| Blackmore, PF; Exton, JH | 1 |
| Endo, Y; Kopf, GS; Schultz, RM | 1 |
| Pines, M; Santora, A; Spiegel, A | 1 |
| Campisi, J; Dean, M; Henkle, C; Levine, RA; Ran, W | 1 |
| Houslay, MD; Irvine, F; Pyne, NJ | 1 |
| Campagnoni, AT; Dawson, G; Szuchet, S; Vartanian, T | 1 |
| Abou-Samra, AB; Aguilera, G; Catt, KJ; Harwood, JP; Manganiello, VC | 1 |
| Eakes, AT; Pike, LJ | 1 |
| Ishitoya, J; Takenawa, T | 1 |
| Basci, A; Shah, SV; Wallin, JD | 1 |
| Fujiki, H; Lazzaro, M; Levine, L; Tashjian, AH | 1 |
| Johnson, RD; Minneman, KP | 1 |
| de Pont, JJ; Tilly, RH; Willems, PH | 1 |
| Machado, AJ; Mallea, LE; Navaroli, F; Rommerts, FF | 1 |
| Niki, A; Niki, H; Niki, I; Tamagawa, T | 1 |
| Dickinson, KE; Hirschowitz, BI; Komiyama, K; Matsumoto, H; Shirakawa, T | 1 |
| Haslam, RJ; Murphy, W; Williams, KA | 1 |
| Kagawa, S; Matsuoka, A; Nakao, K; Wakabayashi, S | 1 |
| Alcorta, DA; Blenis, J; Erikson, RL; Kuo, CJ | 1 |
| Chambaut-Guerin, AM; Thomopoulos, P | 1 |
| Metz, SA | 2 |
| Klein, DC; Sugden, D | 1 |
| Barthelson, RA; Jacoby, DB; Widdicombe, JH | 1 |
| Wong, PY | 1 |
| Sitkovsky, MV; Takayama, H; Trenn, G | 1 |
| Hansel, W; Izhar, M; Shemesh, M; Shore, LS; Strauss, JF | 1 |
| Dieguez, C; Edwards, CA; Ham, J; Peters, JR; Scanlon, MF | 1 |
| Anderson, NG; Hanson, PJ; Hatt, JF; Shaw, GP | 1 |
| Jumblatt, MM; Matkin, ED; Neufeld, AH | 1 |
| Bolaffi, JL; Bruno, L; Grodsky, GM; Heldt, A | 1 |
| Field, JB; Rani, CS | 1 |
| Baird, A; Mormède, P | 1 |
| Lin, JX; Vilcek, J; Zhang, Y | 1 |
| Hirai, S; Piette, J; Yaniv, M | 1 |
| Gilman, MZ | 1 |
| Emoto, T; Hiraiwa, M; Kasai, K; Shimoda, S | 1 |
| Butler, RD; Evans, RL; McCrohan, CR | 1 |
| Rowe, JW; Wang, SY | 1 |
| Field, JB; Haraguchi, K; Rani, CS | 1 |
| Barron, KS; Gilliam, EB; Orson, FM; Patke, CL; Rosenblatt, HM; Shearer, WT | 1 |
| Atwell, MM; Hanson, PJ | 1 |
| Goto, Y; Sugamura, K; Takeshita, T | 1 |
| Levin, EG; Santell, L | 1 |
| Iida, H; Page, E | 1 |
| Hu, JS; Olson, EN | 1 |
| Bauer, K; Hamprecht, B; Kleinkauf, H; Schulz, M | 1 |
| Hansel, W; Izhar, M; Shalem, Z; Shemesh, M; Shore, LS; Strauss, JF | 1 |
| Calavetta, L; Devi, L; Douglass, JO; McMurray, CT | 1 |
| Ray, KP; Wallis, M | 1 |
| Hanson, PJ; Hatt, JF | 1 |
| Goldman, JE; Kume-Iwaki, A; Shafit-Zagardo, B | 1 |
| Baru, M; Manor, H | 1 |
| Conklin, BR; Felder, CC; Ma, AL | 1 |
| Bomsztyk, K; Ostrowski, J | 1 |
| Soll, AH; Toomey, M | 1 |
| Buchou, T; Charollais, RH; Fagot, D; Mester, J | 1 |
| Cohen, DP; Rothstein, TL | 1 |
| Hui, KK; Yu, JL | 1 |
| Borst, SE; Catherwood, BD | 1 |
| Dawson, G; McAtee, P | 1 |
| Bolanowski, MA; Bouvier, M; Caron, MG; Collins, S; Lefkowitz, RJ | 1 |
| Copp, RP; Samuels, HH | 1 |
| Boucher, RC; Cheng, EH; Earp, HS; Knowles, MR; Paradiso, AM; Stutts, MJ | 1 |
| Avruch, J; Deutsch, PJ; Grove, JR; Habener, JF; Price, DJ | 1 |
| Endou, H; Miyanoshita, A; Takahashi, T | 1 |
| Devine, P; Dixon, T; Graber, M | 1 |
| Birnbaum, MJ; Hiraki, Y; McMorrow, IM | 1 |
| Bala, RM; Eatock, BA; Sheppard, MS | 1 |
| Bohnet, HG; DiMattia, GE; Friesen, HG; Gellersen, B | 1 |
| Lüscher, B; Mitchell, PJ; Tjian, R; Williams, T | 1 |
| Danowski, BA | 1 |
| Abrahamsson, L; Esscher, T; Jergil, B; Mattsson, M; Påhlman, S; Ruusala, AI | 1 |
| Boutwell, RK; Perchellet, JP | 4 |
| Marks, F | 1 |
| Rochette-Egly, C; Tovey, MG | 1 |
| Scott, RE; Yun, K | 1 |
| Amsler, K; Cook, JS; Shaffer, C | 1 |
| Novogrodsky, A; Patya, M; Rubin, AL; Stenzel, KH | 1 |
| Fujiki, H; Shimizu, N; Shimizu, Y; Sugimura, T | 1 |
| Nordenberg, J; Novogrodsky, A; Stenzel, KH | 1 |
| Evensen, SA; Galdal, KS; Lyberg, T; Nilsen, E; Prydz, H | 1 |
| Euteneuer, U; Nakamura, T; Porter, KR; Schliwa, M | 1 |
| De Pont, JJ; Van Emst-de Vries, SE; Willems, PH | 1 |
| Bertram, P; Scutt, A; Zeschnigk, M | 1 |
| Cheung, HS; Mitchell, PG | 1 |
| Andersson, T; Löfgren, R; Ng-Sikorski, J; Sjölander, A | 1 |
| Chayvialle, JA; Cuber, JC; Dakka, T | 1 |
| Ailhaud, G; Far, DF; Gaillard, D; Negrel, R; Vassaux, G | 1 |
| Aguila-Mansilla, N; Kedzierski, W; Kozlowski, GP; Porter, JC | 1 |
| Kachra, Z; Posner, BI; Yang, CR | 1 |
| Gohda, E; Iwao, M; Kataoka, H; Matsunaga, T; Takebe, T; Wu, YL; Yamamoto, I | 1 |
| Hauri, HP; Naim, H; Sander, B | 1 |
| Jacobson, K; Meier, K; Watson, EL | 1 |
| Aubert, ML; Bonjour, JP; Rizzoli, R; Sappino, AP | 1 |
| Iitaka, M; Ishii, J; Kitahama, S | 1 |
| Florio, C; Heisler, S; Martin, JG; Styhler, A | 1 |
| Collombel, C; Damour, O; Nakazawa, K | 1 |
| Davis, TP; Mania-Farnell, BL; Merrill, BJ; Yamamura, HI | 1 |
| Kratzmeier, M; McArdle, CA; Poch, A; Schomerus, E | 1 |
| Anderson, S; Miskimins, R | 1 |
| Garton, AJ; Tonks, NK | 1 |
| Bertacca, A; Cini, M; Franceschelli, F; Mazzetti, P; Minks, MA; Simili, M | 1 |
| Kachra, Z; Murphy, LJ; Posner, BI; Yang, CR | 1 |
| DiBattista, JA; Jolicoeur, FC; Martel-Pelletier, J; Morin, N; Pelletier, JP | 1 |
| Vaughan-Jones, RD; Wu, ML | 1 |
| Cramb, G; Gilkes, AF; Guild, SB | 1 |
| Hahn, S; Moroni, C | 1 |
| Fandrey, J; Frede, S; Huwiler, A; Jelkmann, W; Pfeilschifter, J | 1 |
| Grant, K; Ma, TY; Said, HM | 1 |
| Carsberg, CJ; Friedmann, PS; Warenius, HM | 1 |
| Botana, LM; Estévez, MD; Vieytes, MR | 2 |
| Chik, CL; Ho, AK; Inukai, T | 1 |
| Bolton, TB; Prestwich, SA | 1 |
| Houchi, H; Ishimura, Y; Kitamura, K; Minakuchi, K; Ohuchi, T; Oka, M; Okuno, M | 1 |
| Karhunen, T; Pavel, S; Slingerland, R; Smit, N; Tilgmann, C; Ulmanen, I; Westerhof, W | 1 |
| Du, Q; Hu, ZY; Liu, K; Liu, YX; Zhou, HM; Zou, RJ | 1 |
| Menko, WJ; Pavel, S; Smit, NP; Verbeek, NM; Westerhof, W | 1 |
| Ferrante, A; Hii, CS; Murray, AW; Poulos, A; Rathjen, DA; Robinson, BS; Schmidt, S | 1 |
| Alfonso, A; Botana, LM; Estévez, MD; Louzao, MC; Vieytes, MR | 1 |
| Binswanger, U; Forgo, J; Helmle-Kolb, C; Murer, H; Walter, R | 1 |
| Gould, GW; Graham, A; Malarkey, K; McLees, A; Plevin, R | 1 |
| Chik, CL; Ho, AK; Karpinski, E; Kovacs, CS; Li, B | 1 |
| Ahmed, MU; Hazeki, K; Hazeki, O; Katada, T; Ui, M | 1 |
| Houslay, MD; Rena, G; Spence, S; Sweeney, G | 1 |
| Ballotti, R; Durand-Clément, M; Englaro, W; Lallemand, D; Ortonne, JP; Rezzonico, R | 1 |
| Gimenez, C; Krantic, S; Rabourdin-Combe, C | 1 |
| Akaike, N; Uneyama, C; Uneyama, H | 1 |
| Howell, SL; Jones, PM; Persaud, SJ | 1 |
| Caccavelli, L; Chuang, TT; Enjalbert, A; Kordon, C | 1 |
| Ploegh, HL; Schaap, D; van Blitterswijk, WJ; van der Bend, RL; van der Wal, J | 1 |
| Grimes, RW; Hammond, JM; Samaras, SE | 1 |
| Choi, EJ; Dittman, AH; Storm, DR; Wong, ST | 1 |
| Arneson-Rotert, LJ; Liewer, SA; Toews, ML | 1 |
| Cho, H; Katzenellenbogen, BS | 1 |
| Berton, G; Cabrini, G; Dechecchi, MC; Tamanini, A | 1 |
| Hildebrand, P; Jensen, RT; Mantey, SA; Mrozinski, JE; Patto, RJ | 1 |
| Hu, DN; McCormick, SA; Ritch, R | 1 |
| Halaban, R; Longley, J; Rubin, J; Tyrrell, L; Yarden, Y | 1 |
| Augenlicht, LH; Velcich, A | 1 |
| Iba, H; Nishina, H; Sato, H; Suzuki, T; Yoshida, T | 1 |
| Eikvar, L; Eskild, W; Hansson, V; Taskén, KA | 1 |
| Aggarwal, BB; Graff, K; Higuchi, M; Liao, WS; Samal, B | 1 |
| Joshi-Barve, SS; Rangnekar, VM; Rangnekar, VV; Sells, SF | 1 |
| Carrero, I; Guijarro, LG; Pèrez-Albarsanz, MA; Prieto, JC; Recio, MN; Rodríguez-Henche, N | 1 |
| Bali, JP; Gusdinar, T; Hollande, F; Magous, R | 1 |
| Bona, BJ; Borror, KC; DeFranco, DB; Moyer, ML; Nordeen, SK | 1 |
| Boumpas, DT; Kincaid, RL; Paliogianni, F | 1 |
| Nishida, A; Shimizu, M; Yamawaki, S | 1 |
| Di Marzo, V; Piomelli, D; Schwartz, JC; Sokoloff, P; Vial, D | 1 |
| Bascands, JL; Girolami, JP; Pecher, C | 1 |
| Adogu, AA; Ashford, ML; Hales, CN; Khan, RN; Ozanne, SE | 1 |
| Davis, TP; Konings, PN; Mania-Farnell, BL; Merrill, BJ | 1 |
| Bouaboula, M; Bourrié, B; Calandra, B; Canat, X; Casellas, P; Le Fur, G; Poinot-Chazel, C; Rinaldi-Carmona, M | 1 |
| Bos, MP; Feyen, JH; Herrmann-Erlee, MP; Van der Meer, JM | 1 |
| Gopalakrishna, R; Gundimeda, U; He, S; Hinton, DR; Hofman, FM; Ryan, SJ; Sippy, BD; Wang, JL; Wright, AD | 1 |
| Davis, TP; Mania-Farnell, B | 1 |
| Benishin, CG; Karpinski, E; Ren, J | 1 |
| Paulding, WR; Sumners, C | 1 |
| Borger, P; Kauffman, HF; Postma, DS; Vellenga, E; Vijgen, JL | 1 |
| Nystedt, S; Ramakrishnan, V; Sundelin, J | 1 |
| Brittinger, G; Höffkes, HG; Teschendorf, C; Trenn, G | 1 |
| Bonnet, J; Fauchère, JL; Kucharczyk, N; Lesur, C; Pacherie, M; Pastoureau, P; Sabatini, M | 1 |
| Akai, Y; Amemiya, M; Asano, Y; Homma, S; Kusano, E; Ono, S; Takeda, S | 1 |
| Garmey, JC; Lahav, M; Veldhuis, JD | 1 |
| Clauss, W; Liebold, KM; Reifarth, FW; Weber, WM | 1 |
| Babin-Chevaye, C; Franzini, E; Hakim, J; Marquetty, C; Pasquier, C; Sellak, H | 1 |
| Columbo, M; Horowitz, EM; Kagey-Sobotka, A; Lichtenstein, LM | 1 |
| Botros, I; Davis, TP; Day, R; Mania-Farnell, BL | 1 |
| Lundquist, I; Salehi, A | 1 |
| Blenis, J; Monfar, M | 1 |
| Christopoulos, G; Findlay, DM; Houssami, S; Sexton, PM | 1 |
| Diel, P; Flach, R; Gutacker, C; Klock, G; Koch-Brandt, C | 1 |
| Caughey, GH; Fang, KC; Nadel, JA; Sommerhoff, CP | 1 |
| Deeg, MA; Verchere, CB | 1 |
| Carson, DD; Ding, ZM; Kuo, MT; Wegner, CC; Zhou, X | 1 |
| Cabrera Oliva, J; Estévez, F; Fanjul, LF; González Reyes, J; González Robaina, I; Hernández, I; López Blanco, F; Quintana Aguiar, J; Ruiz de Galarreta, CM; Santana, P | 1 |
| Bindels, RJ; Deen, PM; Nielsen, S; van Os, CH | 1 |
| Ding, WG; Gromada, J | 1 |
| Dobson, JG; Ethier, MF | 1 |
| Earp, HS; Graves, LM; Li, X; Yu, H | 1 |
| Brichard, SM; Henquin, JC; Ongemba, LN; Pottier, AM; Reul, BA | 1 |
| Häussinger, D; Kurz, AK; Schliess, F; vom Dahl, S | 1 |
| Lee, HZ | 1 |
| Hashimoto, Y; Inui, K; Nagai, J; Takano, M; Yano, I | 1 |
| Blostein, R; Lane, LK; Nestor, NB | 1 |
| Diecke, FP; Fischbarg, J; Kang, F; Kuang, K; Zhu, Z | 1 |
| Ancellin, N; Barrault, MB; Corman, B; Klingler, C; Morel, A | 1 |
| Chik, CL; Ho, AK; Negishi, T | 1 |
| Bobbin, RP; Chen, C | 1 |
| Chang, CH; Chang, TM; Chey, WY; Coy, DH; Erway, B | 1 |
| Du, X; Guo, Z; Iacovitti, L | 1 |
| Akagi, K; Hasebe, K; Nagao, T; Urushidani, T; Watanabe, K | 1 |
| Drummer, C; Gerzer, R; Herten, M; Lenz, W | 1 |
| Burns, CJ; Harris, TE; Jones, PM; Persaud, SJ | 1 |
| Alfonso, A; Botana, LM; Botana, MA; Vieytes, MR | 1 |
| Bobryshev, AIu; Skok, VI; Voĭtenko, SV | 1 |
| Hohl, CM | 1 |
| Behrman, HR; Duleba, AJ; Olive, DL; Spaczynski, RZ | 1 |
| Bonnamy, PJ; Carreau, S; Grudet, N; Le Goff, D | 1 |
| Evans, RM; Holwell, TA; Reyland, ME; Schweitzer, SC | 1 |
| Blanchard, JM; Coulon, V; Hipskind, RA; Tourkine, N; Veyrune, JL; Vié, A | 1 |
| Christakos, S; Fleischer, N; Meyer, M; Noda, M; Rhoten, WB; Schermerhorn, T; Sharp, GW; Sooy, K; Surana, M | 1 |
| Hamad, AM; Knox, AJ | 1 |
| Belinsky, GS; Morley, P; Tashjian, AH; Whitfield, JF | 1 |
| Bian, JS; Pei, JM; Wong, TM; Zhang, WM | 1 |
| Höllt, V; Kraus, J; Wöltje, M | 1 |
| Belinsky, GS; Tashjian, AH | 1 |
| Cadet, N; Paquin, J | 1 |
| Paquin, J; Petit-Turcotte, C | 1 |
| Aust, G; Nguyen, TB; Scherbaum, WA; Seissler, J; Steinbrenner, H | 1 |
| Chang, CH; Chang, TM; Chey, WY | 1 |
| Clancey, CJ; Lee, WY; Lever, JE; Loflin, P; Peng, H | 1 |
| Armstrong, WM; Lyall, P; Lyall, V | 1 |
| Corcos, L; Galisteo, M; Guillouzo, A; Joannard, F; Lagadic-Gossmann, D; Lerche, C; Rissel, M | 1 |
| Franceschi, RT; McCauley, LK; Ouyang, H; Somerman, MJ; Wang, D | 1 |
| Meadows, HJ; Randall, AD | 1 |
| Berger, A; Hermann, A; Kofler, B; Lang, R | 1 |
| Abou-Samra, AB; Che, J; Qian, F; Tawfeek, HA | 1 |
| Dunlop, J; Hediger, MA; Peng, JB; Trotti, D | 1 |
| Pisarchik, A; Slominski, AT | 1 |
| Chandrasekhar, S; Halladay, DL; Martin, TJ; Miles, RR; Onyia, JE; Thirunavukkarasu, K | 1 |
| Dhillon, AS; Kolch, W; Mischak, H; Pollock, C; Shaw, PE; Steen, H | 1 |
| Bloodsworth, A; Clark, SR; Coles, B; Cross, AR; Freeman, BA; Lewis, MJ; O'Donnell, VB | 1 |
| Chen, DY; Fan, HY; Li, MY; Schatten, H; Song, XF; Sun, QY; Tong, C; Xia, GL | 1 |
| López-Vera, E; Pérez-León, JA; Salceda, R | 1 |
| Bito, T; Fukunaga, M; Kageyama, A; Nagai, H; Nishigori, C; Oka, M | 1 |
| Argiolu, F; Badiali, M; Pillai, R; Reali, C; Ristaldi, MS; Sanna, MA; Scintu, F; Sogos, V | 1 |
| Biggio, G; Cabras, S; Carta, M; Murru, L; Pillai, R; Reali, C; Scintu, F; Scorciapino, L; Sogos, V | 1 |
| Abayasekara, DR; Cheng, Z; Flint, AP; Marshall, E; Sheldrick, EL; Wathes, DC | 1 |
| Basler, T; Goethe, R; Phi-van, L | 1 |
| Chappe, F; Chappe, V; Hanrahan, JW; Loewen, ME | 1 |
| Norante, FA; Taft, AS; Yoshino, TP | 1 |
| Cramer, LP; Cutler, DF; Grimes, W; Lopes da Silva, M; McCormack, JJ; Nightingale, TD; Robinson, C; Vaughan, A; White, IJ | 1 |
1 review(s) available for 1-methyl-3-isobutylxanthine and tetradecanoylphorbol acetate
| Article | Year |
|---|---|
Pigmentation and proliferation of human melanocytes and the effects of melanocyte-stimulating hormone and ultraviolet B light.
Topics: 1-Methyl-3-isobutylxanthine; alpha-MSH; Cell Differentiation; Cell Division; Cells, Cultured; Humans; Infant, Newborn; Melanocyte-Stimulating Hormones; Melanocytes; Protein-Tyrosine Kinases; Receptors, Cell Surface; Signal Transduction; Tetradecanoylphorbol Acetate; Ultraviolet Rays | 1993 |
314 other study(ies) available for 1-methyl-3-isobutylxanthine and tetradecanoylphorbol acetate
| Article | Year |
|---|---|
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Regulation of expression of the chicken ovalbumin gene: interactions between steroid hormones and second messenger systems.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Chickens; Colforsin; Corticosterone; Drug Interactions; Estrogens; Female; Gene Expression Regulation; Insulin; Ovalbumin; Oviducts; Protein Kinase C; Protein Kinases; Recombinant Fusion Proteins; Regulatory Sequences, Nucleic Acid; RNA, Messenger; Second Messenger Systems; Tetradecanoylphorbol Acetate | 1992 |
Translation of heart preproenkephalin mRNA and secretion of enkephalin peptides from cultured cardiac myocytes.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Base Sequence; Cells, Cultured; Enkephalins; Molecular Sequence Data; Myocardium; Nucleic Acid Hybridization; Protein Biosynthesis; Protein Precursors; Radioimmunoassay; Rats; Ribonucleases; RNA, Messenger; Tetradecanoylphorbol Acetate | 1992 |
Calcitonin gene-related peptide stimulates intracellular cAMP via a protein kinase C-controlled mechanism in human ocular ciliary epithelial cells.
Topics: 1-Methyl-3-isobutylxanthine; Alkaloids; Calcitonin; Calcitonin Gene-Related Peptide; Cells, Cultured; Cholera Toxin; Colforsin; Cyclic AMP; Diglycerides; Epithelium; Eye; Fetus; Humans; Kinetics; Phorbol Esters; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate | 1992 |
Pituitary adenylate cyclase polypeptide (PACAP) stimulates cyclic AMP formation in pituitary fibroblasts and 3T3 tumor fibroblasts: lack of enhancement by protein kinase C activation.
Topics: 1-Methyl-3-isobutylxanthine; 3T3 Cells; Adenylate Cyclase Toxin; Animals; Cell Line, Transformed; Colforsin; Corticotropin-Releasing Hormone; Cyclic AMP; Enzyme Activation; Fibroblasts; Male; Mice; Neuropeptides; Pertussis Toxin; Pituitary Adenylate Cyclase-Activating Polypeptide; Pituitary Gland; Protein Kinase C; Rats; Rats, Wistar; Stimulation, Chemical; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1992 |
Maintenance of long-term secretory function by microencapsulated islets of Langerhans.
Topics: 1-Methyl-3-isobutylxanthine; Alginates; Animals; Biocompatible Materials; Enzyme Activation; Glucagon; Glucose; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Membranes, Artificial; Polylysine; Protein Kinase C; Protein Kinases; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate; Time Factors | 1992 |
Forskolin and phorbol ester stimulation of neuropeptide Y (NPY) production and secretion by aggregating fetal brain cells in culture: evidence for regulation of NPY biosynthesis at transcriptional and posttranscriptional levels.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Brain; Cell Aggregation; Cells, Cultured; Colforsin; Cycloheximide; Dactinomycin; Dose-Response Relationship, Drug; Fetus; Hypothalamus; Kinetics; Neuropeptide Y; Olfactory Bulb; Protein Biosynthesis; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate; Transcription, Genetic; Verapamil | 1992 |
Mitogenic, melanogenic, and cAMP responses of cultured neonatal human melanocytes to commonly used mitogens.
Topics: 1-Methyl-3-isobutylxanthine; Cell Division; Cells, Cultured; Cholera Toxin; Cyclic AMP; Dose-Response Relationship, Drug; Fibroblast Growth Factor 2; Humans; In Vitro Techniques; Infant, Newborn; Melanins; Melanocytes; Monophenol Monooxygenase; Recombinant Proteins; Tetradecanoylphorbol Acetate | 1992 |
Heparin suppresses specific second messenger pathways for protooncogene expression in rat vascular smooth muscle cells.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Blotting, Northern; Bucladesine; Calcimycin; Cell Cycle; Cells, Cultured; DNA; Enzyme Activation; Epidermal Growth Factor; Gene Expression Regulation; Genes, fos; Genes, myc; Heparin; Muscle, Smooth, Vascular; Protein Kinase C; Proto-Oncogenes; Rats; RNA, Messenger; Second Messenger Systems; Tetradecanoylphorbol Acetate | 1992 |
Elevated beta-cell calmodulin produces a unique insulin secretory defect in transgenic mice.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Calmodulin; Carbachol; Cells, Cultured; Cytoplasmic Granules; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Mice; Mice, Transgenic; Microscopy, Electron; Radioimmunoassay; Tetradecanoylphorbol Acetate | 1992 |
Effect of adenosine analogues and cAMP-raising agents on TNF-, GM-CSF-, and chemotactic peptide-induced degranulation in single adherent neutrophils.
Topics: 1-Methyl-3-isobutylxanthine; 2-Chloroadenosine; Adenosine; Blood Proteins; Bucladesine; Cell Adhesion; Cell Degranulation; Chemotactic Factors; Colforsin; Cyclic AMP; Cytochalasin B; Exocytosis; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1992 |
Centrosome phosphorylation and the developmental expression of meiotic competence in mouse oocytes.
Topics: 1-Methyl-3-isobutylxanthine; Adenine; Animals; Centrioles; Cytoplasm; Female; Meiosis; Mesothelin; Mice; Microtubules; Nocodazole; Oocytes; Phosphorylation; Tetradecanoylphorbol Acetate | 1992 |
In vitro evidence for modulation of morphological and functional development of hypothalamic immunoreactive atrial natriuretic peptide neurons by cyclic 3',5'-adenosine monophosphate.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Atrial Natriuretic Factor; Cell Count; Colforsin; Colorimetry; Fluorescent Antibody Technique; Hypothalamus; Neurons; Oligonucleotide Probes; Protein Precursors; Rats; Rats, Inbred Strains; RNA, Messenger; Tetradecanoylphorbol Acetate | 1992 |
Serum-induced sensitization of cyclic AMP accumulation in C62B rat glioma cells.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Blood Physiological Phenomena; Cyclic AMP; Glioma; Isoproterenol; Magnesium; Protein Kinase C; Rats; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1992 |
Role of cyclic nucleotides and calcium in the nutrient-induced release of cholecystokinin-like immunoreactivity in rats.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Calcium; Calcium Channels; Cholecystokinin; Colforsin; Dose-Response Relationship, Drug; Duodenum; Jejunum; Nucleotides, Cyclic; Radioimmunoassay; Rats; Receptors, Cholecystokinin; Tetradecanoylphorbol Acetate | 1992 |
Astroglial membrane structure is affected by agents that raise cyclic AMP and by phosphatidylcholine phospholipase C.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Astrocytes; Cattle; Cell Membrane; Cells, Cultured; Colforsin; Cyclic AMP; Freeze Fracturing; Glioma; Guinea Pigs; Immunohistochemistry; Isoproterenol; Lectins; Phosphatidylcholines; Phospholipase D; Protein Kinase C; Protein Kinases; Rats; Retina; Second Messenger Systems; Stimulation, Chemical; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Type C Phospholipases | 1992 |
Effect of cAMP elevating compounds on inhibition of gap junctional communication and induction of morphological transformation in Syrian hamster embryo cells.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Cell Communication; Cell Transformation, Neoplastic; Cells, Cultured; Cholera Toxin; Colforsin; Cricetinae; Cyclic AMP; Embryo, Mammalian; Intercellular Junctions; Mesocricetus; Tetradecanoylphorbol Acetate; Theophylline | 1992 |
Protein kinase C activators sensitize cyclic AMP accumulation by intact 1321N1 human astrocytoma cells.
Topics: 1-Methyl-3-isobutylxanthine; Adenylate Cyclase Toxin; Astrocytoma; Carbachol; Colforsin; Cyclic AMP; Down-Regulation; Enzyme Activation; Humans; Isoproterenol; Pertussis Toxin; Phosphatidylinositols; Protein Kinase C; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Virulence Factors, Bordetella | 1990 |
Involvement of protein kinase C in the regulation of cortisol production by guinea pig adrenocortical cells.
Topics: 1-Methyl-3-isobutylxanthine; Adrenal Cortex; Aminoglutethimide; Angiotensin II; Animals; Cycloheximide; Guinea Pigs; Hydrocortisone; In Vitro Techniques; Male; Protein Kinase C; Tetradecanoylphorbol Acetate | 1990 |
Control of plasminogen activator activity in the thecal layer of the largest preovulatory follicle in the hen ovary.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Calcimycin; Chickens; Cholera Toxin; Cyclic AMP; Dose-Response Relationship, Drug; Female; Luteinizing Hormone; Osmolar Concentration; Ovarian Follicle; Ovary; Ovulation; Plasminogen Activators; Prostaglandins; Tetradecanoylphorbol Acetate; Theca Cells | 1990 |
Forskolin-induced desensitization of pancreatic beta-cell insulin secretory responsiveness: possible involvement of impaired information flow in the inositol-lipid cycle.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Colforsin; Cyclic AMP; Diacylglycerol Kinase; Diglycerides; Glucose; Glycerides; Inositol; Insulin; Insulin Secretion; Islets of Langerhans; Male; Phosphatidylinositols; Phosphotransferases; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate | 1990 |
Regulation of insulin secretion from beta-cell lines derived from transgenic mice insulinomas resembles that of normal beta-cells.
Topics: 1-Methyl-3-isobutylxanthine; Adenoma, Islet Cell; Animals; Carbachol; Colforsin; Cyclic AMP; Drug Synergism; Glipizide; Glucose; Insulin; Insulin Secretion; Insulinoma; Islets of Langerhans; Kinetics; Mice; Mice, Transgenic; Pancreatic Neoplasms; Potassium; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1990 |
cAMP-mediated modulation of signal transduction of epidermal growth factor (EGF) receptor systems in human epidermoid carcinoma A431 cells. Depression of EGF-dependent diacylglycerol production and EGF receptor phosphorylation.
Topics: 1-Methyl-3-isobutylxanthine; Alprostadil; Carcinoma, Squamous Cell; Cell Line; Cell Membrane; Cholera Toxin; Colforsin; Cyclic AMP; Diglycerides; Epidermal Growth Factor; ErbB Receptors; Glycerides; Humans; Kinetics; Peptide Mapping; Phosphopeptides; Phosphorylation; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1990 |
Synthesis and secretion of somatostatin-28 and -14 by fetal rat intestinal cells in culture.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Blotting, Northern; Bucladesine; Butyrates; Butyric Acid; Cells, Cultured; Chromatography, Gel; Colforsin; Ethanol; Fetus; Fluorescent Antibody Technique; Intestinal Mucosa; Intestines; Protein Precursors; Rats; Rats, Inbred Strains; RNA; RNA, Messenger; Somatostatin; Somatostatin-28; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1990 |
Glucocorticoid repression of 3',5'-cyclic-adenosine monophosphate-dependent human corticotropin-releasing-hormone gene promoter activity in a transfected mouse anterior pituitary cell line.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Cell Line; Chloramphenicol O-Acetyltransferase; Corticotropin-Releasing Hormone; Cyclic AMP; Dexamethasone; DNA, Recombinant; Drug Synergism; Gene Expression Regulation; Mice; Pituitary Gland, Anterior; Promoter Regions, Genetic; Regulatory Sequences, Nucleic Acid; Restriction Mapping; Tetradecanoylphorbol Acetate; Transfection | 1990 |
Iloprost inhibits neutrophil-induced lung injury and neutrophil adherence to endothelial monolayers.
Topics: 1-Methyl-3-isobutylxanthine; Adenine; Adenylyl Cyclase Inhibitors; Animals; Cell Adhesion; Cyclic AMP; Iloprost; In Vitro Techniques; Macrophage-1 Antigen; Male; Neutrophils; Nifedipine; Permeability; Phosphodiesterase Inhibitors; Rats; Respiratory Distress Syndrome; Superoxides; Tetradecanoylphorbol Acetate | 1990 |
Successful culture of adult human melanocytes obtained from normal and vitiligo donors.
Topics: 1-Methyl-3-isobutylxanthine; Adult; Biopsy; Calcium; Catalase; Cell Division; Cells, Cultured; Cholera Toxin; Culture Media; Culture Techniques; Growth Substances; Humans; Melanocytes; Reference Values; Tetradecanoylphorbol Acetate; Vitiligo | 1990 |
Cyclic AMP increases thrombomodulin expression on membrane surface of cultured human umbilical vein endothelial cells.
Topics: 1-Methyl-3-isobutylxanthine; Bucladesine; Cell Membrane; Cells, Cultured; Cyclic AMP; Endothelium, Vascular; Epoprostenol; Humans; Platelet Aggregation Inhibitors; Receptors, Cell Surface; Receptors, Thrombin; Tetradecanoylphorbol Acetate; Thrombin | 1990 |
Modulation of the constitutive gene expression of the 55 kD tumor necrosis factor receptor in hematopoietic cells.
Topics: 1-Methyl-3-isobutylxanthine; Bucladesine; Carcinoma, Hepatocellular; Colforsin; Gene Expression Regulation; Humans; Leukemia, Promyelocytic, Acute; Leukocytes, Mononuclear; Liver Neoplasms; Molecular Weight; Neutrophils; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Receptors, Cell Surface; Receptors, Tumor Necrosis Factor; Recombinant Proteins; Reference Values; RNA; RNA, Neoplasm; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Necrosis Factor-alpha | 1990 |
Cyclic AMP stimulates luteinizing-hormone (lutropin) exocytosis in permeabilized sheep anterior-pituitary cells. Synergism with protein kinase C and calcium.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine Triphosphate; Animals; Calcium; Cell Membrane Permeability; Cyclic AMP; Drug Synergism; Exocytosis; Gonadotropin-Releasing Hormone; Intracellular Fluid; Luteinizing Hormone; Pituitary Gland, Anterior; Protein Kinase C; Sheep; Stimulation, Chemical; Tetradecanoylphorbol Acetate | 1990 |
Regulation of intracellular Ca2+ oscillation in AR42J cells.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Calcium; Cell Line; Kinetics; Oscillometry; Pancreas; Sincalide; Spectrometry, Fluorescence; Tetradecanoylphorbol Acetate; Time Factors | 1990 |
Studies of receptor-mediated inhibition of 45Ca accumulation into synaptosomes.
Topics: 1-Methyl-3-isobutylxanthine; 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Bucladesine; Calcium; Calcium Radioisotopes; Clonidine; In Vitro Techniques; L-Lactate Dehydrogenase; Male; Mitochondria; Pyrrolidines; Rats; Rats, Inbred Strains; Receptors, Drug; Synaptosomes; Tetradecanoylphorbol Acetate; Vanadates | 1990 |
Down-regulation of tyrosinase mRNA levels in melanoma cells by tumor promoters and by insulin.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Bucladesine; Enzyme Induction; Gene Expression Regulation, Neoplastic; Insulin; Melanocyte-Stimulating Hormones; Melanoma, Experimental; Mice; Monophenol Monooxygenase; Phorbol 12,13-Dibutyrate; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1990 |
Modulation of Gs activity by phorbol myristate acetate in rat hepatocytes.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Animals; Cell Membrane; Cells, Cultured; Cholera Toxin; Cyclic AMP; Female; GTP-Binding Proteins; Guanylyl Imidodiphosphate; Kinetics; Liver; Protein Kinase C; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate | 1991 |
Stimulation of chicken growth hormone release by phorbol esters.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Cells, Cultured; Chickens; Colforsin; Cyclic AMP; Drug Interactions; Enzyme Activation; Growth Hormone; Growth Hormone-Releasing Hormone; Pancreas; Phorbol 12,13-Dibutyrate; Phorbol Esters; Pituitary Gland, Anterior; Protein Kinase C; Tetradecanoylphorbol Acetate; Thyrotropin-Releasing Hormone | 1990 |
cAMP-dependent protein kinase activation affects vasopressin V2-receptor number and internalization in LLC-PK1 renal epithelial cells.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Arginine Vasopressin; Cell Line; Enzyme Activation; Epithelium; Kidney; Kinetics; Protein Kinases; Receptors, Angiotensin; Receptors, Vasopressin; Tetradecanoylphorbol Acetate; Vasopressins | 1991 |
Inhibition of luteinizing-hormone exocytosis by guanosine 5'-[gamma-thio]triphosphate reveals involvement of a GTP-binding protein distal to second-messenger generation.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine Triphosphate; Animals; Calcium; Cell Membrane Permeability; Cells, Cultured; Cyclic AMP; Egtazic Acid; Exocytosis; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanylyl Imidodiphosphate; Kinetics; Luteinizing Hormone; Pituitary Gland, Anterior; Second Messenger Systems; Sheep; Tetradecanoylphorbol Acetate | 1991 |
Regulation of phospholipase D-induced hydrolysis of choline-containing phosphoglycerides by cyclic AMP in human neutrophils.
Topics: 1-Methyl-3-isobutylxanthine; Cyclic AMP; Dinoprostone; Humans; Hydrolysis; In Vitro Techniques; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphatidic Acids; Phosphatidylcholines; Phospholipase D; Tetradecanoylphorbol Acetate | 1991 |
Characterization of the 3',5'-cyclic adenosine monophosphate-mediated regulation of IL2 production by T cells and Jurkat cells.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Adult; Cell Line; Cholera Toxin; Cyclic AMP; Dinoprostone; Humans; Interleukin-2; Leukemia; Phosphatidylinositols; T-Lymphocytes; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1991 |
Modulation of responsiveness to cAMP stimulating agonists by phorbol ester in fetal rat osteoblasts.
Topics: 1-Methyl-3-isobutylxanthine; Adenylate Cyclase Toxin; Animals; Cells, Cultured; Cyclic AMP; Dose-Response Relationship, Drug; In Vitro Techniques; Osteoblasts; Parathyroid Hormone; Pertussis Toxin; Protein Kinase C; Rats; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1991 |
Insulin and other regulatory factors modulate the growth and the phosphoenolpyruvate carboxykinase (PEPCK) activity of primary rabbit kidney proximal tubule cells in serum free medium.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Blood; Cell Division; Cell Fractionation; Cells, Cultured; Culture Media; Cyclic AMP; Growth Substances; Insulin; Kidney Tubules, Proximal; Phosphoenolpyruvate Carboxykinase (GTP); Rabbits; Receptor, Insulin; Tetradecanoylphorbol Acetate | 1991 |
The possibility of participation of different protein kinases in the regulation of degradation of Glp6[125I]Tyr8SP6-11 with different endopeptidases in subcellular fractions of rat brain.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine Triphosphate; Animals; Brain; Cell Nucleus; Cerebral Cortex; Colforsin; Cyclic AMP; Cyclic GMP; Endopeptidases; Hippocampus; Neurotransmitter Agents; Peptide Fragments; Protease Inhibitors; Protein Kinases; Pyrrolidonecarboxylic Acid; Rats; Second Messenger Systems; Subcellular Fractions; Substance P; Synaptosomes; Tetradecanoylphorbol Acetate | 1991 |
Mammalian cell lines engineered to identify inhibitors of specific signal transduction pathways.
Topics: 1-Methyl-3-isobutylxanthine; Alkaline Phosphatase; Animals; Base Sequence; Cell Line; Clone Cells; Colforsin; Female; Humans; Isoenzymes; Mice; Molecular Sequence Data; Placenta; Platelet-Derived Growth Factor; Pregnancy; Signal Transduction; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transfection | 1991 |
Expression of genes related to the extracellular matrix in human endothelial cells. Differential modulation by elevated glucose concentrations, phorbol esters, and cAMP.
Topics: 1-Methyl-3-isobutylxanthine; Basement Membrane; Blotting, Northern; Cells, Cultured; Colforsin; Collagen; Cyclic AMP; Endothelium, Vascular; Extracellular Matrix; Fibronectins; Gene Expression Regulation; Glucose; Humans; Microbial Collagenase; Protein Kinase C; Protein Kinases; RNA, Messenger; Tetradecanoylphorbol Acetate; Tissue Plasminogen Activator; Transcription, Genetic | 1991 |
Activation of AP-1 by IL-1 and phorbol esters in T cells. Role of protein kinase A and protein phosphatases.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Colforsin; Cyclic AMP; DNA-Binding Proteins; Dose-Response Relationship, Drug; Drug Synergism; Ethers, Cyclic; Gene Expression Regulation; Interleukin-1; Mice; Okadaic Acid; Phosphoprotein Phosphatases; Protein Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-jun; Signal Transduction; T-Lymphocytes; Tetradecanoylphorbol Acetate; Thymoma; Transcription Factors; Transcription, Genetic; Transfection; Tumor Cells, Cultured | 1991 |
Second messenger pathways mediating chicken luteinizing hormone secretion from dispersed pituitary cells.
Topics: 1-Methyl-3-isobutylxanthine; Alkaloids; Animals; Arachidonic Acids; Calcimycin; Calcium; Carcinogens; Chickens; Cyclic AMP; Diglycerides; Dose-Response Relationship, Drug; Epidermal Growth Factor; Gonadotropin-Releasing Hormone; Luteinizing Hormone; Male; Pituitary Gland; Protein Kinase C; Second Messenger Systems; Staurosporine; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin; Transforming Growth Factor alpha | 1991 |
Modification of biological responses to interleukin-1 by agents that perturb signal transduction pathways.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Cell Division; Cell Line; Cholera Toxin; Colforsin; Cyclic AMP; Diglycerides; Dinoprostone; Flow Cytometry; Interleukin-1; Interleukin-2; Lymphocyte Activation; Mice; Pertussis Toxin; Protein Kinase C; Recombinant Proteins; Signal Transduction; T-Lymphocytes, Cytotoxic; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1991 |
Cyclic AMP-mediated modulation of immunoglobulin production in B cells by prostaglandin E1.
Topics: 1-Methyl-3-isobutylxanthine; Alprostadil; Antibody Formation; B-Lymphocytes; Cell Line; Cyclic AMP; Dinoprost; Dose-Response Relationship, Drug; Humans; Immunoglobulin M; Immunoglobulins; In Vitro Techniques; Tetradecanoylphorbol Acetate | 1991 |
Intracellular mechanisms involved in the stimulation of growth hormone release from rat anterior pituitary cells by Russell's viper venom.
Topics: 1-Methyl-3-isobutylxanthine; Aminoquinolines; Animals; Calcium; Cells, Cultured; Culture Media; Cyclic AMP; Growth Hormone; Pituitary Gland, Anterior; Rats; Tetradecanoylphorbol Acetate; Verapamil; Viper Venoms | 1990 |
Regulation of Na-K-2Cl cotransport in osteoblasts.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Carrier Proteins; Cell Line; Chlorides; Colforsin; Cyclic AMP; Dinoprostone; Egtazic Acid; Kinetics; Osteoblasts; Osteosarcoma; Ouabain; Parathyroid Hormone; Potassium; Rubidium; Second Messenger Systems; Sodium; Sodium-Potassium-Chloride Symporters; Tetradecanoylphorbol Acetate | 1991 |
Hepatocanalicular organic-anion transport is regulated by protein kinase C.
Topics: 1-Methyl-3-isobutylxanthine; Alkaloids; Animals; Anion Transport Proteins; Anions; Bile Canaliculi; Biological Transport; Bucladesine; Carrier Proteins; Colforsin; Cyclic AMP; Glucagon; Glutathione; Male; Protein Kinase C; Rats; Rats, Inbred Strains; Second Messenger Systems; Staurosporine; Tetradecanoylphorbol Acetate; Vasopressins | 1991 |
Regulation of vasopressin messenger RNA levels in the small cell lung carcinoma cell line GLC-8: interactions between glucocorticoids and second messengers.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Aldosterone; Carcinoma, Small Cell; Cell Line; Cyclic AMP; Dexamethasone; Gene Expression Regulation, Neoplastic; Humans; Hydrocortisone; Lung Neoplasms; Receptors, Glucocorticoid; RNA, Messenger; Second Messenger Systems; Tetradecanoylphorbol Acetate; Transcription, Genetic; Vasopressins | 1991 |
Regulation by forskolin of cyclic AMP phosphodiesterase and protein kinase C activity in LLC-PK1 cells.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Alkaloids; Animals; Cells, Cultured; Colforsin; Cyclic GMP; Galactose; Macaca mulatta; Pregnenolone; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate | 1991 |
Inhibition of cell proliferation, protein kinase C, and phorbol ester-induced fos expression by the dihydropyridine derivative B859-35.
Topics: 1-Methyl-3-isobutylxanthine; 3T3 Cells; Animals; Base Sequence; Calcium Channel Blockers; Carrier Proteins; Cell Division; Chloramphenicol O-Acetyltransferase; Cytosol; Dihydropyridines; Enhancer Elements, Genetic; Gene Expression; Genes, fos; Humans; Hydrogen-Ion Concentration; Kinetics; Mice; Molecular Sequence Data; Phosphatidylserines; Protein Kinase C; Recombinant Fusion Proteins; Sodium-Hydrogen Exchangers; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transfection | 1991 |
Pleiotropic effect of okadaic acid on maturing mouse oocytes.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Cell Membrane; Cells, Cultured; Cytoskeleton; Ethers, Cyclic; Fluorescent Antibody Technique; Meiosis; Mesothelin; Mice; Microtubules; Okadaic Acid; Oocytes; Phosphoprotein Phosphatases; Tetradecanoylphorbol Acetate | 1991 |
Protein kinase C down-regulation enhances cAMP-mediated induction of urokinase-type plasminogen activator mRNA in LLC-PK1 cells.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Blotting, Northern; Bucladesine; Cell Line; Colforsin; Cyclic AMP; Enzyme Activation; Gene Expression; Protein Kinase C; Protein Kinases; RNA, Messenger; Swine; Tetradecanoylphorbol Acetate; Transcription, Genetic; Urokinase-Type Plasminogen Activator | 1991 |
Role of pertussis toxin-sensitive G proteins in stimulus-dependent human eosinophil degranulation.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine Diphosphate Ribose; Antigens, Differentiation; Calcimycin; Cell Degranulation; Cholera Toxin; Cyclic AMP; Eosinophil-Derived Neurotoxin; Eosinophils; GTP-Binding Proteins; Humans; In Vitro Techniques; N-Formylmethionine Leucyl-Phenylalanine; Neurotoxins; Pertussis Toxin; Phosphatidylinositols; Receptors, Fc; Receptors, Formyl Peptide; Receptors, IgG; Receptors, Immunologic; Ribonucleases; Tetradecanoylphorbol Acetate; Time Factors; Virulence Factors, Bordetella | 1991 |
Dual mechanism of angiotensin II inhibits ANP-induced mesangial cGMP accumulation.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-GMP Phosphodiesterases; Angiotensin II; Animals; Atrial Natriuretic Factor; Cells, Cultured; Cyclic GMP; Glomerular Mesangium; Guanylate Cyclase; Isoquinolines; Kinetics; Piperazines; Protein Kinase C; Tetradecanoylphorbol Acetate | 1991 |
Regulation of peptide-YY synthesis and secretion in fetal rat intestinal cultures.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Calcimycin; Cells, Cultured; Chromatography, High Pressure Liquid; Colforsin; Drug Synergism; Gastric Inhibitory Polypeptide; Gastrin-Releasing Peptide; Immunoenzyme Techniques; Intestinal Mucosa; Intestines; Peptide Biosynthesis; Peptide YY; Peptides; Protein Kinase C; Protein Kinases; Rats; Rats, Inbred Strains; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate | 1991 |
Phorbol 12-myristate-13-acetate (PMA) stimulates a differential expression of cholecystokinin (CCK) and c-fos mRNA in a human neuroblastoma cell line.
Topics: 1-Methyl-3-isobutylxanthine; Base Sequence; Cell Line; Cholecystokinin; Gene Expression Regulation, Neoplastic; Humans; Molecular Sequence Data; Neuroblastoma; Protein Kinase C; Proto-Oncogene Mas; Proto-Oncogene Proteins c-fos; RNA, Messenger; Tetradecanoylphorbol Acetate | 1991 |
Macrophages express functional receptors for calcitonin-gene-related peptide.
Topics: 1-Methyl-3-isobutylxanthine; Amiloride; Animals; Calcitonin; Calcitonin Gene-Related Peptide; Carrier Proteins; Cyclic AMP; Hydrogen-Ion Concentration; Macrophages; Peritoneal Cavity; Rats; Receptors, Calcitonin; Receptors, Cell Surface; Sodium-Hydrogen Exchangers; Sphingosine; Tetradecanoylphorbol Acetate | 1991 |
Effects of cyclic AMP and phorbol ester on transepithelial electrical resistance of Sertoli cell monolayers in two-compartment culture.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Bucladesine; Cells, Cultured; Cholera Toxin; Colforsin; Cyclic AMP; Electric Conductivity; Epithelium; Follicle Stimulating Hormone; Intercellular Junctions; Male; Rats; Rats, Inbred Strains; Second Messenger Systems; Sertoli Cells; Tetradecanoylphorbol Acetate | 1991 |
Differential regulation of gene expression by estrogen in estrogen growth-independent and -dependent MCF-7 human breast cancer cell sublines.
Topics: 1-Methyl-3-isobutylxanthine; Breast Neoplasms; Cell Line, Transformed; Clone Cells; Down-Regulation; Epidermal Growth Factor; Estradiol; Female; Gene Expression Regulation; Humans; Polyunsaturated Alkamides; Receptors, Cell Surface; Receptors, Estradiol; Receptors, Progesterone; RNA, Messenger; Tetradecanoylphorbol Acetate; Time Factors; Transcription, Genetic | 1991 |
Tributyltin stimulates reactive oxygen formation in toadfish macrophages.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Benzoates; Benzoic Acid; Calcimycin; Calcium; Calcium Channels; Fishes; Free Radical Scavengers; Free Radicals; Indomethacin; Luminescent Measurements; Macrophage Activation; Macrophages; Masoprocol; Oxygen; Superoxide Dismutase; Tetradecanoylphorbol Acetate; Trialkyltin Compounds; Trifluoperazine; Verapamil | 1991 |
Prostaglandin F2 alpha stimulates cAMP phosphodiesterase via protein kinase C in cultured human granulosa cells.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Adult; Cells, Cultured; Cloprostenol; Cyclic AMP; Dinoprost; Female; Granulosa Cells; Humans; Kinetics; Progesterone; Protein Kinase C; Tetradecanoylphorbol Acetate | 1991 |
Triiodothyronine (T3) inhibition of growth hormone secretion by chicken pituitary cells in vitro.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Analysis of Variance; Animals; Calcimycin; Cells, Cultured; Chickens; Colforsin; Diglycerides; Dose-Response Relationship, Drug; Growth Hormone; Growth Hormone-Releasing Hormone; In Vitro Techniques; Male; Pituitary Gland, Anterior; Radioimmunoassay; Second Messenger Systems; Tetradecanoylphorbol Acetate; Triiodothyronine | 1991 |
Differential and coordinate regulation of TH and PNMT mRNAs in chromaffin cell cultures by second messenger system activation and steroid treatment.
Topics: 1-Methyl-3-isobutylxanthine; Adrenal Medulla; Animals; Cattle; Cells, Cultured; Colforsin; Cyclic AMP; Dexamethasone; Enzyme Induction; Phenylethanolamine N-Methyltransferase; RNA, Messenger; Second Messenger Systems; Stimulation, Chemical; Tetradecanoylphorbol Acetate; Tyrosine 3-Monooxygenase | 1991 |
Effect of aging on the sensitivity of pancreatic beta-cells to insulin secretagogues in rats.
Topics: 1-Methyl-3-isobutylxanthine; Aging; Animals; Blood Glucose; Female; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Rats; Rats, Wistar; Tetradecanoylphorbol Acetate; Tolbutamide | 1991 |
Thyroid cell responses to thyrotropin and 12-O-tetradecanoyl-phorbol-13-acetate: translocation of protein kinase C and phosphorylation of thyroid cell polypeptide substrates.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Cattle; Cyclic AMP; Dogs; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Molecular Weight; Peptides; Phorbols; Phosphorylation; Protein Kinase C; Tetradecanoylphorbol Acetate; Thyroid Gland; Thyrotropin; Time Factors | 1985 |
Beta-adrenergic stimulation of anterior pituitary cyclic AMP is enhanced by tumor promoters.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Cyclic AMP; In Vitro Techniques; Isoproterenol; Male; Phorbol 12,13-Dibutyrate; Phorbol Esters; Pituitary Gland, Anterior; Protein Kinase C; Rats; Receptors, Adrenergic, beta; Tetradecanoylphorbol Acetate | 1985 |
Regulation of the terminal event in cellular differentiation: biological mechanisms of the loss of proliferative potential.
Topics: 1-Methyl-3-isobutylxanthine; Adipose Tissue; Amanitins; Animals; Blood Proteins; Cell Cycle; Cell Differentiation; Cell Line; Culture Media; Cycloheximide; Deoxyadenosines; Humans; Mice; Puromycin; Tetradecanoylphorbol Acetate; Time Factors; Tretinoin | 1986 |
Ca2+-, phorbol ester-, and cAMP-stimulated enzyme secretion from permeabilized rat pancreatic acini.
Topics: 1-Methyl-3-isobutylxanthine; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Amylases; Animals; Calcium; Carbachol; Cell Membrane Permeability; Colforsin; Cyclic AMP; Cytoplasmic Granules; Digitonin; Egtazic Acid; Pancreas; Phorbols; Rats; Rats, Inbred Strains; Saponins; Spermine; Tetradecanoylphorbol Acetate; Trifluoperazine | 1986 |
Human melanocytes cultured from nevi and melanomas.
Topics: 1-Methyl-3-isobutylxanthine; Adult; Aged; Cell Division; Cell Separation; Cells, Cultured; Child; Cholera Toxin; Female; Humans; Infant, Newborn; Male; Melanocytes; Melanoma; Middle Aged; Nevus; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1986 |
P19, a hormonally regulated phosphoprotein of peptide hormone-producing cells: secretagogue-induced phosphorylation in AtT-20 mouse pituitary tumor cells and in rat and hamster insulinoma cells.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Adenoma, Islet Cell; Adrenocorticotropic Hormone; Animals; Colforsin; Corticotropin-Releasing Hormone; Cricetinae; Cyclic AMP; Electrophoresis, Polyacrylamide Gel; Glucagon; Insulinoma; Isoproterenol; Pancreatic Neoplasms; Phosphoproteins; Phosphorylation; Pituitary Neoplasms; Potassium; Rats; Tetradecanoylphorbol Acetate | 1986 |
Studies on the hepatic calcium-mobilizing activity of aluminum fluoride and glucagon. Modulation by cAMP and phorbol myristate acetate.
Topics: 1-Methyl-3-isobutylxanthine; Adenylate Cyclase Toxin; Adrenergic alpha-Agonists; Aluminum; Aluminum Compounds; Angiotensin II; Calcium; Colforsin; Cyclic AMP; Drug Synergism; Fluorides; Glucagon; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Liver; Pertussis Toxin; Phorbols; Protein Kinase C; Sodium Fluoride; Tetradecanoylphorbol Acetate; Thionucleotides; Vasopressins; Virulence Factors, Bordetella | 1986 |
Stage-specific changes in protein phosphorylation accompanying meiotic maturation of mouse oocytes and fertilization of mouse eggs.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Blastocyst; Egg Proteins; Female; Fertilization; Meiosis; Metaphase; Mice; Molecular Weight; Oocytes; Phosphoproteins; Phosphorylation; Superovulation; Tetradecanoylphorbol Acetate | 1986 |
Effects of phorbol esters and pertussis toxin on agonist-stimulated cyclic AMP production in rat osteosarcoma cells.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Cell Line; Cyclic AMP; Drug Synergism; Interphase; Osteosarcoma; Pertussis Toxin; Phorbol 12,13-Dibutyrate; Phorbol Esters; Rats; Tetradecanoylphorbol Acetate; Time Factors; Virulence Factors, Bordetella | 1986 |
Induction of c-fos and c-myc mRNA by epidermal growth factor or calcium ionophore is cAMP dependent.
Topics: 1-Methyl-3-isobutylxanthine; Blood Physiological Phenomena; Calcimycin; Calcium; Cholera Toxin; Cyclic AMP; Drug Synergism; Epidermal Growth Factor; Proto-Oncogenes; RNA, Messenger; Tetradecanoylphorbol Acetate | 1986 |
The phorbol ester TPA inhibits cyclic AMP phosphodiesterase activity in intact hepatocytes.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Cyclic AMP; Drug Synergism; Glucagon; Liver; Male; Rats; Tetradecanoylphorbol Acetate | 1986 |
Oligodendrocyte adhesion activates protein kinase C-mediated phosphorylation of myelin basic protein.
Topics: 1-Methyl-3-isobutylxanthine; Adult; Calcimycin; Cell Adhesion; Colforsin; Cyclic AMP; Enzyme Activation; Humans; Myelin Basic Protein; Neuroglia; Oligodendroglia; Phosphorylation; Protein Kinase C; Tetradecanoylphorbol Acetate | 1986 |
Phorbol 12-myristate 13-acetate and vasopressin potentiate the effect of corticotropin-releasing factor on cyclic AMP production in rat anterior pituitary cells. Mechanisms of action.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Adrenocorticotropic Hormone; Animals; Cells, Cultured; Corticotropin-Releasing Hormone; Cyclic AMP; Drug Synergism; Female; Guanosine Triphosphate; Kinetics; Male; Pituitary Gland, Anterior; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate; Vasopressins | 1987 |
Epidermal growth factor stimulates the production of phosphatidylinositol monophosphate and the breakdown of polyphosphoinositides in A431 cells.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Bucladesine; Cell Line; Cholera Toxin; Chromatography, Thin Layer; Epidermal Growth Factor; Lipid Metabolism; Pertussis Toxin; Phosphatidylinositol Phosphates; Phosphatidylinositols; Phosphorylation; Tetradecanoylphorbol Acetate; Time Factors; Virulence Factors, Bordetella | 1987 |
Potentiation of PGE1-induced increase in cyclic AMP by chemotactic peptide and Ca2+ ionophore through calmodulin-dependent processes.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Alprostadil; Animals; Calcimycin; Calmodulin; Colforsin; Cyclic AMP; Drug Synergism; Female; Guanosine Triphosphate; Guinea Pigs; Membrane Proteins; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Prostaglandin Antagonists; Sulfonamides; Tetradecanoylphorbol Acetate | 1987 |
Effect of stimulated neutrophils on cyclic nucleotide content in isolated rat glomeruli.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Catalase; Cyclic AMP; Cyclic GMP; Kidney Glomerulus; Lymphocyte Activation; Neutrophils; Rats; Rats, Inbred Strains; Superoxide Dismutase; Tetradecanoylphorbol Acetate; Zymosan | 1987 |
Palytoxin: an extraordinarily potent stimulator of prostaglandin production and bone resorption in cultured mouse calvariae.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Acrylamides; Animals; Bone and Bones; Bone Resorption; Cnidarian Venoms; Cyclic AMP; Dinoprostone; Epidermal Growth Factor; Growth Substances; Indomethacin; Mice; Organ Culture Techniques; Parathyroid Hormone; Peptides; Prostaglandins E; Tetradecanoylphorbol Acetate; Transforming Growth Factors | 1987 |
Differentiation of alpha 1-adrenergic receptors linked to phosphatidylinositol turnover and cyclic AMP accumulation in rat brain.
Topics: 1-Methyl-3-isobutylxanthine; Alkylating Agents; Animals; Aspirin; Brain; Brain Mapping; Calcium; Clonidine; Cyclic AMP; In Vitro Techniques; Indomethacin; Phenethylamines; Phosphatidylinositols; Rats; Receptors, Adrenergic, alpha; Tetradecanoylphorbol Acetate; Tetralones | 1987 |
Pertussis toxin stimulates cholecystokinin-induced cyclic AMP formation but is without effect on secretagogue-induced calcium mobilization in exocrine pancreas.
Topics: 1-Methyl-3-isobutylxanthine; Adenylate Cyclase Toxin; Amylases; Animals; Calcium; Cholecystokinin; Cyclic AMP; Cytosol; In Vitro Techniques; Pancreas; Pertussis Toxin; Rabbits; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1987 |
Modulation of stimulatory action of follicle stimulating hormone (FSH) and inhibitory action of epidermal growth factor (EGF) on aromatase activity in Sertoli cells by calcium.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Aromatase; Aromatase Inhibitors; Bucladesine; Calcium; Egtazic Acid; Enzyme Activation; Epidermal Growth Factor; Estradiol; Follicle Stimulating Hormone; Male; Protein Kinase C; Rats; Rats, Inbred Strains; Sertoli Cells; Tetradecanoylphorbol Acetate | 1987 |
Regulation of insulin release independent of changes of cytosolic Ca2+ concentration.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Calcium; Colforsin; Cyclic AMP; Cytosol; Digitonin; Epinephrine; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Male; Norepinephrine; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate | 1986 |
Synergism between cellular messengers and agonist combinations in pepsinogen secretion.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Bethanechol; Bethanechol Compounds; Bombesin; Calcimycin; Calcium; Cell Communication; Colforsin; Cyclic AMP; Drug Synergism; Esophagus; Fluorescent Antibody Technique; Isoproterenol; L-Lactate Dehydrogenase; Pepsinogens; Protein Kinase C; Rana catesbeiana; Tetradecanoylphorbol Acetate | 1987 |
Effects of activation of protein kinase C on the agonist-induced stimulation and inhibition of cyclic AMP formation in intact human platelets.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine Diphosphate; Alprostadil; Blood Platelets; Colforsin; Cyclic AMP; Diglycerides; Enzyme Activation; Epinephrine; Humans; Prostaglandin D2; Prostaglandins D; Protein Kinase C; Tetradecanoylphorbol Acetate | 1987 |
Development and function of B cells in monolayer islet cells of 3-week-old rat.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Cells, Cultured; Colforsin; Deoxyglucose; Fluorodeoxyglucose F18; Insulin; Insulin Secretion; Iodoacetates; Iodoacetic Acid; Islets of Langerhans; Microscopy, Phase-Contrast; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate; Time Factors | 1987 |
Role of second messengers in regulating the growth-associated S6 protein kinase activity.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Avian Sarcoma Viruses; Bucladesine; Calcimycin; Cell Transformation, Neoplastic; Chick Embryo; Cyclic AMP; Fibroblasts; Inositol Phosphates; Kinetics; Phosphorylation; Protein Kinases; Proto-Oncogenes; Tetradecanoylphorbol Acetate | 1987 |
Protein kinase C potentiates isoproterenol-mediated cyclic AMP production without modifying the homologous desensitization process in J774 cells.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Animals; Carcinogens; Cell Line; Cell Membrane; Cyclic AMP; Isoproterenol; Kinetics; Macrophages; Mice; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; Receptors, Adrenergic, beta; Tetradecanoylphorbol Acetate | 1987 |
Epinephrine impairs insulin release by a mechanism distal to calcium mobilization. Similarity to lipoxygenase inhibitors.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Bucladesine; Calcium; Calcium Radioisotopes; Epinephrine; Exocytosis; Insulin; Insulin Secretion; Islets of Langerhans; Lipoxygenase Inhibitors; Pertussis Toxin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella; Yohimbine | 1988 |
Activators of protein kinase C act at a postreceptor site to amplify cyclic AMP production in rat pinealocytes.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adrenergic alpha-Agonists; Animals; Cholera Toxin; Colforsin; Cyclic AMP; Enzyme Activation; Female; Phenylephrine; Phorbol Esters; Pineal Gland; Protein Kinase C; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Tetradecanoylphorbol Acetate | 1988 |
Regulation of chloride secretion in dog tracheal epithelium by protein kinase C.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Bucladesine; Chlorides; Cyclic AMP; Diglycerides; Dogs; Electric Conductivity; Epithelium; Histones; Indomethacin; Isoproterenol; Phosphorylation; Protein Kinase C; Protein Kinases; Tetradecanoylphorbol Acetate; Trachea | 1987 |
Mechanism of adrenergic stimulation of anion secretion in cultured rat epididymal epithelium.
Topics: 1-Methyl-3-isobutylxanthine; 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; Amiloride; Animals; Bicarbonates; Bumetanide; Calcimycin; Calcium Channel Blockers; Cells, Cultured; Electric Conductivity; Epididymis; Epinephrine; Epithelium; Male; Rats; Rats, Inbred Strains; Sympathomimetics; Tetradecanoylphorbol Acetate | 1988 |
Locus of inhibitory action of cAMP-dependent protein kinase in the antigen receptor-triggered cytotoxic T lymphocyte activation pathway.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Calcimycin; Cholera Toxin; Colforsin; Cyclic AMP; Cytotoxicity, Immunologic; Exocytosis; Lymphocyte Activation; Protein Kinases; Receptors, Antigen, T-Cell; T-Lymphocytes, Cytotoxic; Tetradecanoylphorbol Acetate | 1988 |
Control of bovine placental progesterone synthesis: roles of cholesterol availability and calcium-activated systems.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Calcimycin; Calcium; Cattle; Cholesterol; Drug Interactions; Female; Hydroxycholesterols; Placenta; Pregnancy; Progesterone; Tetradecanoylphorbol Acetate; Trifluoperazine | 1988 |
Evidence that growth hormone depletion and uncoupling of the regulatory protein of adenylate cyclase (Ns) both contribute to the desensitization of growth hormone responses to growth hormone-releasing factor.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Cells, Cultured; Cholera Toxin; Colforsin; Cyclic AMP; Growth Hormone; Growth Hormone-Releasing Hormone; GTP-Binding Proteins; Pituitary Gland, Anterior; Rats; Tetradecanoylphorbol Acetate | 1988 |
Action of epidermal growth factor on acid secretion by rat isolated parietal cells.
Topics: 1-Methyl-3-isobutylxanthine; Aminopyrine; Animals; Bucladesine; Epidermal Growth Factor; Flurbiprofen; Gastric Acid; Histamine; Imidazoles; In Vitro Techniques; Male; Parietal Cells, Gastric; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate | 1987 |
Pharmacological regulation of morphology and mitosis in cultured rabbit corneal endothelium.
Topics: 1-Methyl-3-isobutylxanthine; Actins; Animals; Cell Count; Culture Techniques; Endothelium, Corneal; Epidermal Growth Factor; Indomethacin; Male; Microscopy, Electron; Mitosis; Rabbits; Tetradecanoylphorbol Acetate; Toxins, Biological | 1988 |
Characteristics of desensitization of insulin secretion in fully in vitro systems.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Colforsin; Glucose; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Keto Acids; Kinetics; Male; Rats; Tetradecanoylphorbol Acetate; Time Factors | 1988 |
Comparison of effects of thyrotropin, phorbol esters, norepinephrine, and carbachol on iodide organification in dog thyroid slices, follicles, and cultured cells.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Biological Transport; Bucladesine; Carbachol; Cyclic AMP; Dogs; In Vitro Techniques; Iodides; Kinetics; Norepinephrine; Tetradecanoylphorbol Acetate; Thyroid Gland; Thyrotropin | 1988 |
Estrogens, cyclic adenosine 3',5'-monophosphate, and phorbol esters modulate the prolactin response of GH3 cells to basic fibroblast growth factor.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Cell Line; Cyclic AMP; Drug Interactions; Estradiol; Fibroblast Growth Factors; Growth Hormone; Kinetics; Pituitary Neoplasms; Prolactin; Rats; Tetradecanoylphorbol Acetate; Thyrotropin-Releasing Hormone | 1988 |
Synthesis of interleukin 6 (interferon-beta 2/B cell stimulatory factor 2) in human fibroblasts is triggered by an increase in intracellular cyclic AMP.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Alprostadil; Bucladesine; Cholera Toxin; Cyclic AMP; Dactinomycin; Enzyme Activation; Fibroblasts; Humans; Interleukin-6; Interleukins; Protein Kinase C; Tetradecanoylphorbol Acetate | 1988 |
Constitutive synthesis of activator protein 1 transcription factor after viral transformation of mouse fibroblasts.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Bucladesine; Cell Line, Transformed; Cell Nucleus; Cell Transformation, Viral; Culture Media; Cyclic AMP; DNA-Binding Proteins; Mice; Proto-Oncogene Proteins c-jun; Simian virus 40; Tetradecanoylphorbol Acetate; Transcription Factors | 1988 |
The c-fos serum response element responds to protein kinase C-dependent and -independent signals but not to cyclic AMP.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Base Sequence; Blood; Colforsin; Cyclic AMP; Fibroblasts; Gene Expression Regulation; Growth Substances; Mice; Mice, Inbred BALB C; Mutation; Oligonucleotides; Promoter Regions, Genetic; Protein Kinase C; Proto-Oncogenes; Tetradecanoylphorbol Acetate; Transfection | 1988 |
Phorbol esters modulate cyclic AMP accumulation in porcine thyroid cells.
Topics: 1-Methyl-3-isobutylxanthine; Alprostadil; Animals; Cells, Cultured; Cholera Toxin; Colforsin; Cyclic AMP; Dinoprostone; Phorbol 12,13-Dibutyrate; Phorbol Esters; Prostaglandins E; Swine; Tetradecanoylphorbol Acetate; Thyroid Gland; Thyrotropin | 1988 |
Dantrolene-induced inhibition of insulin release. A mechanism independent of effects on calcium fluxes.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Arachidonic Acid; Arachidonic Acids; Calcium; Dantrolene; Fatty Acids; Hydroxymercuribenzoates; Insulin; Insulin Secretion; Male; Phospholipases A; Phospholipases A2; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate; Trifluoperazine; Type C Phospholipases | 1988 |
Tentacle contraction in Heliophrya erhardi (Suctoria): the role of inositol phospholipid metabolites and cyclic nucleotides in stimulus-response coupling.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Bucladesine; Chlorides; Ciliophora; Cyclic AMP; Cyclic GMP; Dibutyryl Cyclic GMP; Inositol Phosphates; Lithium; Lithium Chloride; Muscle Contraction; Pyrimidinones; Sugar Phosphates; Tetradecanoylphorbol Acetate; Thiazoles | 1988 |
Age-related impairment in the short term regulation of insulin biosynthesis by glucose in rat pancreatic islets.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Aging; Animals; Dactinomycin; Electrophoresis, Polyacrylamide Gel; Glucose; Insulin; Islets of Langerhans; Male; Proinsulin; Protein Kinase C; Protein Precursors; Rats; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1988 |
Effects of thyrotropin, carbachol, and protein kinase-C stimulators on glucose transport and glucose oxidation by primary cultures of dog thyroid cells.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Bucladesine; Calcium Channel Blockers; Carbachol; Cells, Cultured; Cholera Toxin; Cyclic AMP; Deoxy Sugars; Deoxyglucose; Dogs; Glucose; Kinetics; Norepinephrine; Protein Kinase C; Reference Values; Tetradecanoylphorbol Acetate; Thyroid Gland; Thyrotropin | 1988 |
Effects of a phorbol ester, a calcium ionophore, and 3',5'-adenosine monophosphate production on hen granulosa cell plasminogen activator activity.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 1-Methyl-3-isobutylxanthine; Animals; Calcimycin; Chickens; Cyclic AMP; Cycloheximide; Dactinomycin; Female; Granulosa Cells; In Vitro Techniques; Isoquinolines; L-Lactate Dehydrogenase; Luteinizing Hormone; Piperazines; Plasminogen Activators; Progesterone; Protein Kinase C; Sheep; Tetradecanoylphorbol Acetate | 1988 |
Modulation of a human lymphoblastoid B cell line by cyclic AMP. Ig secretion and phosphatidylcholine metabolism.
Topics: 1-Methyl-3-isobutylxanthine; Adjuvants, Immunologic; B-Lymphocytes; Bucladesine; Cell Line, Transformed; Cholera Toxin; Choline; Colforsin; Cyclic AMP; Humans; Immunoglobulins; Phosphatidylcholines; Phosphorus Radioisotopes; Tetradecanoylphorbol Acetate | 1988 |
Effect of pertussis toxin on the inhibition of secretory activity by prostaglandin E2, somatostatin, epidermal growth factor and 12-O-tetradecanoylphorbol 13-acetate in parietal cells from rat stomach.
Topics: 1-Methyl-3-isobutylxanthine; Aminopyrine; Animals; Dinoprostone; Epidermal Growth Factor; GTP-Binding Proteins; Histamine; Kinetics; Male; Parietal Cells, Gastric; Pertussis Toxin; Rats; Rats, Inbred Strains; Reference Values; Somatostatin; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1988 |
Adenosine 3',5'-cyclic monophosphate (cAMP) inhibits phorbol ester-induced growth of an IL-2-dependent T cell line.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Bucladesine; Cell Division; Cell Line; Cholera Toxin; Colforsin; Cyclic AMP; DNA Replication; Humans; Interleukin-2; Kinetics; Phorbol 12,13-Dibutyrate; Recombinant Proteins; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1988 |
Cyclic AMP potentiates phorbol ester stimulation of tissue plasminogen activator release and inhibits secretion of plasminogen activator inhibitor-1 from human endothelial cells.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Bucladesine; Cells, Cultured; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Drug Synergism; Endothelium, Vascular; Glycoproteins; Humans; Phorbol Esters; Plasminogen Inactivators; Tetradecanoylphorbol Acetate; Tissue Plasminogen Activator | 1988 |
Inhibition of atrial natriuretic peptide secretion by forskolin in noncontracting cultured atrial myocytes.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Atrial Natriuretic Factor; Bucladesine; Calcium; Cells, Cultured; Colforsin; Cyclic GMP; Egtazic Acid; Muscle Contraction; Muscle, Smooth, Vascular; Protein Kinase C; Ryanodine; Sarcoplasmic Reticulum; Secretory Rate; Tetradecanoylphorbol Acetate | 1988 |
Regulation of differentiation of the BC3H1 muscle cell line through cAMP-dependent and -independent pathways.
Topics: 1-Methyl-3-isobutylxanthine; Alprostadil; Animals; Bucladesine; Cell Differentiation; Cell Line; Colforsin; Creatine Kinase; Cyclic AMP; Fibroblast Growth Factors; Kinetics; Mice; Muscles; Ornithine Decarboxylase; Proto-Oncogenes; Receptors, Cholinergic; RNA; RNA, Messenger; Tetradecanoylphorbol Acetate; Transforming Growth Factors; Troponin; Troponin T | 1988 |
Regulation by dibutyryl cyclic AMP of carnosine synthesis in astroglia-rich primary cultures kept in serum-free medium.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Bucladesine; Carnosine; Cells, Cultured; Colforsin; Culture Media; Dexamethasone; Dipeptides; Insulin; Mice; Neuroglia; Tetradecanoylphorbol Acetate; Transferrin | 1989 |
Control of bovine placental progestin synthesis: calcium dependent steroidogenesis is modulated at the site of the cholesterol side chain cleavage enzyme.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Calcimycin; Calcium; Cattle; Cells, Cultured; Cholesterol Side-Chain Cleavage Enzyme; Cyanoketone; Hydroxycholesterols; Placenta; Pregnenolone; Progesterone; Progestins; Protein Kinase C; Rabbits; Tetradecanoylphorbol Acetate | 1988 |
Regulated expression of the prodynorphin gene in the R2C Leydig tumor cell line.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Blotting, Northern; Cyclic AMP; Dynorphins; Enkephalin, Leucine; Enkephalins; Gene Expression Regulation; Leydig Cell Tumor; Male; Mice; Nucleic Acid Hybridization; Pro-Opiomelanocortin; Protein Precursors; Rats; RNA, Messenger; Testicular Neoplasms; Testis; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Cells, Cultured | 1989 |
Regulation of growth hormone secretion and cyclic AMP metabolism in ovine pituitary cells: interactions involved in activation induced by growth hormone-releasing hormone and phorbol esters.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Colforsin; Cyclic AMP; Growth Hormone; Growth Hormone-Releasing Hormone; Phorbol Esters; Pituitary Gland; Sheep; Tetradecanoylphorbol Acetate; Time Factors | 1988 |
Sites of action of protein kinase C on secretory activity in rat parietal cells.
Topics: 1-Methyl-3-isobutylxanthine; Aminopyrine; Animals; Bucladesine; Carrier Proteins; Cyclic AMP; Diglycerides; Dose-Response Relationship, Drug; Enzyme Activation; Gastric Acid; Histamine; Male; Parietal Cells, Gastric; Potassium; Protein Kinase C; Rats; Rats, Inbred Strains; Sodium-Hydrogen Exchangers; Tetradecanoylphorbol Acetate; Thiocyanates | 1989 |
Astrocytes regulate GFAP mRNA levels by cyclic AMP and protein kinase C-dependent mechanisms.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Astrocytes; Bucladesine; Cells, Cultured; Colforsin; Cyclic AMP; Glial Fibrillary Acidic Protein; Humans; Protein Kinase C; RNA, Messenger; Tetradecanoylphorbol Acetate | 1988 |
Induction of polyomavirus DNA replication by cyclic AMP and a tumor promoter.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Cell Line, Transformed; Colforsin; Cyclic AMP; Cycloheximide; DNA Replication; Polyomavirus; Protein Biosynthesis; Tetradecanoylphorbol Acetate; Virus Replication | 1988 |
Carbachol-induced reverse transformation of Chinese hamster ovary cells transfected with and expressing the m5 muscarinic acetylcholine receptor.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Bucladesine; Carbachol; Cell Line; Cell Transformation, Neoplastic; Cholecystokinin; Cricetinae; Cyclic AMP; Dinoprostone; Female; Kinetics; Ovary; Receptors, Muscarinic; Tetradecanoylphorbol Acetate; Transfection | 1989 |
Preproenkephalin mRNA expression in developing rat heart and in cultured ventricular cardiac muscle cells.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Cells, Cultured; Enkephalins; Gene Expression Regulation; Heart; Muscle, Smooth, Vascular; Myocardium; Protein Precursors; Rats; Rats, Inbred Strains; RNA, Messenger; Tetradecanoylphorbol Acetate | 1989 |
Interaction of signal transduction pathways in mediating acid secretion by rat parietal cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 1-Methyl-3-isobutylxanthine; Aminopyrine; Animals; Bucladesine; Cell Membrane; Diglycerides; Female; Gastric Acid; Histamine; Isoquinolines; Parietal Cells, Gastric; Piperazines; Protein Kinase C; Rats; Rats, Inbred Strains; Signal Transduction; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1989 |
Beta-adrenergic and prostanoid inhibition of canine fundic mucosal mast cells.
Topics: 1-Methyl-3-isobutylxanthine; Adrenergic beta-Antagonists; Animals; Calcimycin; Colforsin; Concanavalin A; Cyclic AMP; Dinoprostone; Dogs; Enprostil; Epinephrine; Gastric Fundus; Gastric Mucosa; Histamine Release; Isoproterenol; Liver; Mast Cells; Propanolamines; Propranolol; Prostaglandins E, Synthetic; Tetradecanoylphorbol Acetate | 1989 |
Mitogenic activity of phorbol esters and insulin-like growth factor 1 in chemically transformed mouse fibroblasts BP-A31: independent effects and differential sensitivity to inhibition by 3-isobutyl-1-methyl xanthine.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Blotting, Northern; Cell Division; Cell Transformation, Neoplastic; Colforsin; Cyclic AMP; Cycloheximide; Epidermal Growth Factor; Gene Expression Regulation; Insulin; Insulin-Like Growth Factor I; Mice; Platelet-Derived Growth Factor; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fos; Somatomedins; Suramin; Tetradecanoylphorbol Acetate; Theophylline | 1989 |
Adenosine 3',5'-cyclic monophosphate modulates the mitogenic responses of murine B lymphocytes.
Topics: 1-Methyl-3-isobutylxanthine; Animals; B-Lymphocytes; Bucladesine; Cell Division; Cyclic AMP; Cytochalasin D; Cytochalasins; Ethers; Immunoglobulin Fab Fragments; In Vitro Techniques; Ionomycin; Mice; Mice, Inbred A; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1989 |
Effects of protein kinase inhibitor, 1-(5-isoquinolinylsulfonyl)-2-methylpiperazine, on beta-2 adrenergic receptor activation and desensitization in intact human lymphocytes.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 1-Methyl-3-isobutylxanthine; Adult; Cyclic AMP; Drug Synergism; Humans; Iodocyanopindolol; Isoproterenol; Isoquinolines; Lymphocytes; Pindolol; Piperazines; Protein Kinase Inhibitors; Receptors, Adrenergic, beta; Tetradecanoylphorbol Acetate | 1989 |
Regulation of osteosarcoma EGF receptor affinity by phorbol ester and cyclic AMP.
Topics: 1-Methyl-3-isobutylxanthine; Colforsin; Cyclic AMP; Epidermal Growth Factor; ErbB Receptors; Humans; Iodine Radioisotopes; Osteosarcoma; Parathyroid Hormone; Tetradecanoylphorbol Acetate | 1989 |
Rapid dephosphorylation of protein kinase C substrates by protein kinase A activators results from inhibition of diacylglycerol release.
Topics: 1-Methyl-3-isobutylxanthine; Alprostadil; Animals; Arachidonic Acid; Arachidonic Acids; Biological Transport; Bradykinin; Brain; Bucladesine; Colforsin; Cricetinae; Diglycerides; Enzyme Activation; Glycerides; Hybrid Cells; Inositol Phosphates; Kinetics; Mice; Molecular Weight; Neuroblastoma; Phosphates; Phosphatidylinositols; Phosphoproteins; Phosphorylation; Protein Kinase C; Protein Kinases; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1989 |
cAMP stimulates transcription of the beta 2-adrenergic receptor gene in response to short-term agonist exposure.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Base Sequence; Cell Line; Cell Membrane; Colforsin; Cricetinae; Cyclic AMP; Epinephrine; Genes; Glioma; Kinetics; Rats; Receptors, Adrenergic, beta; RNA, Messenger; Tetradecanoylphorbol Acetate; Theophylline; Transcription, Genetic | 1989 |
Identification of an adenosine 3',5'-monophosphate (cAMP)-responsive region in the rat growth hormone gene: evidence for independent and synergistic effects of cAMP and thyroid hormone on gene expression.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Base Sequence; Cell Line; Chromosome Deletion; Colforsin; Cyclic AMP; Drug Synergism; Gene Expression Regulation; Genes; Growth Hormone; Molecular Sequence Data; Promoter Regions, Genetic; Rats; RNA, Messenger; Tetradecanoylphorbol Acetate; Theophylline; Thionucleotides; Transcription, Genetic; Triiodothyronine | 1989 |
Regulation of androstenedione production by adenosine 3',5'-monophosphate and phorbol myristate acetate in ovarian thecal cells of the domestic hen.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Androstenedione; Animals; Cells, Cultured; Chickens; Cholera Toxin; Cyclic AMP; Diglycerides; Female; Kinetics; Luteinizing Hormone; Tetradecanoylphorbol Acetate; Theca Cells | 1989 |
Chloride secretory response of cystic fibrosis human airway epithelia. Preservation of calcium but not protein kinase C- and A-dependent mechanisms.
Topics: 1-Methyl-3-isobutylxanthine; Adolescent; Adult; Amiloride; Bradykinin; Calcimycin; Calcium; Child; Chlorides; Cyclic AMP; Cystic Fibrosis; Electric Conductivity; Epithelium; Female; Humans; Isoproterenol; Male; Nasal Mucosa; Protein Kinase C; Tetradecanoylphorbol Acetate | 1989 |
Plasmids encoding PKI(1-31), a specific inhibitor of cAMP-stimulated gene expression, inhibit the basal transcriptional activity of some but not all cAMP-regulated DNA response elements in JEG-3 cells.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Carrier Proteins; Cell Line; Cyclic AMP; Enzyme Inhibitors; Gene Expression; Humans; Intracellular Signaling Peptides and Proteins; Kinetics; Peptide Fragments; Plasmids; Protein Kinases; Tetradecanoylphorbol Acetate; Theophylline; Transcription, Genetic; Transfection | 1989 |
Inhibitory effect of cyclic AMP on phorbol ester-stimulated production of reactive oxygen metabolites in rat glomeruli.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Bucladesine; Colforsin; Cyclic AMP; Kidney Glomerulus; Kinetics; Luminescent Measurements; Male; Oxygen; Protein Kinase C; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate; Theophylline | 1989 |
Phorbol myristate acetate inhibits acidification by turtle urinary bladder.
Topics: 1-Methyl-3-isobutylxanthine; Acetazolamide; Animals; Azides; Bicarbonates; Bucladesine; Carbon Dioxide; Cyclic AMP; Hydrogen-Ion Concentration; In Vitro Techniques; Kinetics; Membrane Potentials; Sodium Azide; Tetradecanoylphorbol Acetate; Turtles; Urinary Bladder | 1989 |
The regulation of glucose transporter gene expression by cyclic adenosine monophosphate in NIH3T3 fibroblasts.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Anisomycin; Biological Transport, Active; Cholera Toxin; Colforsin; Cyclic AMP; Fibroblasts; Gene Expression Regulation; Glucose; In Vitro Techniques; Monosaccharide Transport Proteins; Protein Kinase C; Rats; RNA; Tetradecanoylphorbol Acetate | 1989 |
Altered release of growth hormone from dispersed adenohypophysial cells of streptozotocin diabetic rats. II. Effects of a phorbol ester and secretagogues which increase cyclic AMP.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Cholera Toxin; Colforsin; Cyclic AMP; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Growth Hormone; Growth Hormone-Releasing Hormone; Male; Pituitary Gland, Anterior; Rats; Rats, Inbred Strains; Somatostatin; Tetradecanoylphorbol Acetate | 1989 |
Phorbol ester stimulates prolactin release but reduces prolactin mRNA in the human B-lymphoblastoid cell line IM-9-P3.
Topics: 1-Methyl-3-isobutylxanthine; B-Lymphocytes; Blotting, Northern; Bucladesine; Cell Line; Cyclic AMP; Dose-Response Relationship, Drug; Humans; Prolactin; Protein Kinase C; RNA, Messenger; Tetradecanoylphorbol Acetate | 1989 |
Regulation of transcription factor AP-2 by the morphogen retinoic acid and by second messengers.
Topics: 1-Methyl-3-isobutylxanthine; Binding Sites; Blotting, Western; Calcimycin; Cell Differentiation; Colforsin; Cyclic AMP; DNA Probes; DNA-Binding Proteins; Gene Expression Regulation; Humans; Plasmids; RNA, Messenger; Second Messenger Systems; Tetradecanoylphorbol Acetate; Transcription Factor AP-2; Transcription Factors; Transcription, Genetic; Transfection; Tretinoin | 1989 |
Fibroblast contractility and actin organization are stimulated by microtubule inhibitors.
Topics: 1-Methyl-3-isobutylxanthine; Actins; Alkaloids; Animals; Antineoplastic Agents, Phytogenic; Cell Movement; Colforsin; Demecolcine; Fibroblasts; Mice; Mice, Inbred Strains; Microscopy, Fluorescence; Microtubules; Nocodazole; Paclitaxel; Photomicrography; Tetradecanoylphorbol Acetate; Vinblastine | 1989 |
12-O-tetradecanoyl-phorbol-13-acetate-induced differentiation of human neuroblastoma cells is not accompanied by an increase in the intracellular concentration of cyclic AMP.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Carrier Proteins; Clone Cells; Colchicine; Cyclic AMP; Mice; Neoplasms, Experimental; Neuroblastoma; Phorbols; Protein Binding; Tetradecanoylphorbol Acetate | 1985 |
Enhancement by 3-isobutyl-1-methylxanthine and cholera toxin of 12-O-tetradecanoylphorbol-13-acetate-stimulated cyclic nucleotide levels and ornithine decarboxylase activity in isolated epidermal cells.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Carboxy-Lyases; Cell Separation; Cells, Cultured; Cholera Toxin; Cyclic AMP; Cyclic GMP; Epidermis; Mice; Nucleotides, Cyclic; Ornithine Decarboxylase; Phorbols; Tetradecanoylphorbol Acetate; Theophylline; Time Factors | 1980 |
Prevention of phorbol ester-induced catecholamine refractoriness by inhibitors of protein and RNA biosynthesis in mouse epidermis in vivo.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Catecholamines; Cyclic AMP; Cycloheximide; Female; Fluorides; Isoproterenol; Kinetics; Mice; Phorbols; Skin; Tetradecanoylphorbol Acetate; Theophylline | 1980 |
Effects of 3-isobutyl-1-methylxanthine and cyclic nucleotides on 12-O-tetradecanoylphorbol-13-acetate-induced ornithine decarboxylase activity in mouse epidermis in vivo.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Carboxy-Lyases; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Female; Mice; Ornithine Decarboxylase; Phorbols; Skin; Tetradecanoylphorbol Acetate; Theophylline; Time Factors | 1981 |
Effects of 3-isobutyl-1-methylxanthine and cyclic nucleotides on the biochemical processes linked to skin tumor promotion by 12-O-tetradecanoylphorbol-13-acetate.
Topics: 1-Methyl-3-isobutylxanthine; Administration, Topical; Animals; Cocarcinogenesis; Cyclic AMP; Cyclic GMP; DNA, Neoplasm; Dose-Response Relationship, Drug; Female; Mice; Neoplasms, Experimental; Ornithine Decarboxylase; Papilloma; Phorbols; Skin Neoplasms; Tetradecanoylphorbol Acetate; Theophylline | 1981 |
Rapid increase in guanosine 3',5'-cyclic-monophosphate interferon treated mouse leukemia L1210 cells: relationship to the development of the antiviral state and inhibition of cell multiplication.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Calcium; Cell Division; Cyclic AMP; Cyclic GMP; Indomethacin; Interferons; Kinetics; Leukemia L1210; Mice; Tetradecanoylphorbol Acetate; Vesicular stomatitis Indiana virus; Virus Replication | 1981 |
Comparison of the effects of 3-isobutyl-1-methylxanthine and adenosine cyclic 3':5'-monophosphate on the induction of skin tumors by the initiation-promotion protocol and by the complete carcinogenesis process.
Topics: 1-Methyl-3-isobutylxanthine; 9,10-Dimethyl-1,2-benzanthracene; Animals; Cyclic AMP; DNA; Female; In Vitro Techniques; Mice; Mice, Inbred Strains; Polyamines; Protein Biosynthesis; RNA; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Theophylline | 1982 |
Biological mechanisms of phorbol myristate acetate-induced inhibition of proadipocyte differentiation.
Topics: 1-Methyl-3-isobutylxanthine; Adipose Tissue; Animals; Cell Differentiation; Interphase; Mice; Mice, Inbred BALB C; Phenotype; Phorbols; Tetradecanoylphorbol Acetate; Time Factors | 1983 |
Growth-dependent AIB and meAIB uptake in LLC-PK1 cells: effects of differentiation inducers and of TPA.
Topics: 1-Methyl-3-isobutylxanthine; Acetamides; Aminoisobutyric Acids; Animals; Biological Transport, Active; Cell Division; Cell Line; Kidney; Membrane Potentials; Ouabain; Phorbols; Protein Biosynthesis; RNA; Sodium; Swine; Tetradecanoylphorbol Acetate; Theophylline | 1983 |
Agents that increase cellular cAMP inhibit production of interleukin-2, but not its activity.
Topics: 1-Methyl-3-isobutylxanthine; Alprostadil; Animals; Cyclic AMP; Cytotoxicity, Immunologic; Interleukin-2; Kinetics; Lymphocytes; Mice; Mice, Inbred BALB C; Phorbols; Prostaglandins E; Tetradecanoylphorbol Acetate; Theophylline; Thymus Gland | 1983 |
Distinct inhibitory effects of dihydroteleocidin B and the phorbol ester tumor promoters on the adipocyte differentiation of 3T3-L1 cells.
Topics: 1-Methyl-3-isobutylxanthine; Adipose Tissue; Alkaloids; Animals; Carcinogens; Cell Differentiation; Dexamethasone; Fibroblasts; Lyngbya Toxins; Mice; Phorbols; Tetradecanoylphorbol Acetate; Time Factors | 1983 |
12-0-tetradecanoylphorbol-13-acetate and concanavalin A enhance glucose uptake in thymocytes by different mechanisms.
Topics: 1-Methyl-3-isobutylxanthine; 3-O-Methylglucose; Animals; Biological Transport, Active; Bucladesine; Concanavalin A; Deoxy Sugars; Deoxyglucose; Egtazic Acid; Female; Kinetics; Lymphocytes; Methylglucosides; Methylglycosides; Mice; Mice, Inbred BALB C; Phorbols; Tetradecanoylphorbol Acetate; Thymus Gland | 1983 |
Inhibition of the thromboplastin response of endothelial cells in vitro.
Topics: 1-Methyl-3-isobutylxanthine; Cells, Cultured; Dose-Response Relationship, Drug; Endothelium; Endotoxins; Gallic Acid; Homocysteine; Humans; In Vitro Techniques; Tetradecanoylphorbol Acetate; Thromboplastin; Tubercidin | 1984 |
A tumor promoter induces rapid and coordinated reorganization of actin and vinculin in cultured cells.
Topics: 1-Methyl-3-isobutylxanthine; Actins; Animals; Benzimidazoles; Bucladesine; Cell Line; Chlorocebus aethiops; Cytoskeleton; Fluorescent Antibody Technique; Intermediate Filament Proteins; Kidney; Microscopy, Electron; Microtubules; Muscle Proteins; Nocodazole; Phorbols; Tetradecanoylphorbol Acetate; Vimentin; Vinculin | 1984 |
Cholecystokinin-stimulated enzyme secretion from dispersed rabbit pancreatic acinar cells: phosphorylation-dependent changes in potency and efficacy.
Topics: 1-Methyl-3-isobutylxanthine; Alkaloids; Amylases; Animals; Calcium-Transporting ATPases; Cells, Cultured; Cholecystokinin; Colforsin; Cyclic AMP; Enzyme Activation; Enzyme Inhibitors; Pancreas; Phosphodiesterase Inhibitors; Phosphorylation; Protein Kinase Inhibitors; Protein Kinases; Rabbits; Sincalide; Staurosporine; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin; Time Factors | 1995 |
PGE2 induces the transition from non-adherent to adherent bone marrow mesenchymal precursor cells via a cAMP/EP2-mediated mechanism.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Bone Marrow; Bone Marrow Cells; Bucladesine; Cell Adhesion; Cells, Cultured; Colforsin; Colony-Forming Units Assay; Cyclic AMP; Dexamethasone; Dinoprostone; Female; Hematopoietic Stem Cells; Kinetics; Phosphodiesterase Inhibitors; Protein Kinases; Rats; Rats, Wistar; Receptors, Prostaglandin E; Tetradecanoylphorbol Acetate | 1995 |
Protein kinase regulation of tumor necrosis factor alpha stimulated collagenase and stromelysin message levels in chondrocytes.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 1-Methyl-3-isobutylxanthine; Animals; Blotting, Northern; Cartilage, Articular; Cell Membrane; Cells, Cultured; Colforsin; Collagenases; Cyclic AMP; Enzyme Induction; Gene Expression Regulation; Isoquinolines; Kinetics; Matrix Metalloproteinase 3; Metalloendopeptidases; Neoplasm Proteins; Piperazines; Protein Kinase C; Recombinant Proteins; RNA, Messenger; Swine; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1993 |
Beta 2 integrin engagement triggers actin polymerization and phosphatidylinositol trisphosphate formation in non-adherent human neutrophils.
Topics: 1-Methyl-3-isobutylxanthine; Actin Cytoskeleton; Actins; Antigens, CD; Calcium; CD18 Antigens; Cell Adhesion; Cyclic AMP; Humans; In Vitro Techniques; Integrins; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphatidylinositol Phosphates; Signal Transduction; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1993 |
Functional coupling between the active transport of glucose and the secretion of intestinal neurotensin in rats.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Atropine; Biological Transport, Active; Calcium Channel Blockers; Cyclic AMP; Glucose; Ileum; In Vitro Techniques; Intestinal Absorption; Intestine, Small; Jejunum; Male; Neurotensin; Ouabain; Phloretin; Radioimmunoassay; Rats; Rats, Wistar; Tetradecanoylphorbol Acetate; Tetrodotoxin | 1993 |
Inhibition of prostacyclin-induced Ca2+ mobilization by phorbol esters in Ob1771 preadipocytes.
Topics: 1-Methyl-3-isobutylxanthine; Adipose Tissue; Animals; Calcium; Cell Line; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dinoprost; Enzyme Activation; Epoprostenol; Isoproterenol; Male; Mice; Mice, Inbred C57BL; Mice, Obese; Phorbol Esters; Second Messenger Systems; Stem Cells; Tetradecanoylphorbol Acetate | 1993 |
Expression of tyrosine hydroxylase gene in cultured hypothalamic cells: roles of protein kinase A and C.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; Dihydroxyphenylalanine; Dopamine; Gene Expression; Hypothalamus; Naphthalenes; Neurons; Polycyclic Compounds; Protein Kinase C; Rats; Rats, Inbred Strains; RNA, Messenger; Tetradecanoylphorbol Acetate; Tyrosine 3-Monooxygenase | 1994 |
The augmentation of insulin-like growth factor-I messenger ribonucleic acid in cultured rat hepatocytes: activation of protein kinase-A and -C is necessary, but not sufficient.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 1-Methyl-3-isobutylxanthine; Alkaloids; Animals; Blotting, Northern; Bucladesine; Cattle; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; Cycloheximide; Drug Synergism; Enzyme Activation; Glucagon; Growth Hormone; Insulin-Like Growth Factor I; Isoquinolines; Kinetics; Liver; Male; Piperazines; Protein Kinase C; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sphingosine; Staurosporine; Tetradecanoylphorbol Acetate | 1994 |
Expression of hepatocyte growth factor is up-regulated through activation of a cAMP-mediated pathway.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Bucladesine; Cells, Cultured; Cholera Toxin; Colforsin; Cyclic AMP; Dexamethasone; Dinoprostone; Female; Fibroblasts; Gene Expression; Hepatocyte Growth Factor; Humans; Infant; Kinetics; Protein Kinase C; Recombinant Proteins; RNA, Messenger; Skin; Tetradecanoylphorbol Acetate; Transforming Growth Factor beta | 1994 |
Induction of lactase biosynthesis in the human intestinal epithelial cell line Caco-2.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Adenocarcinoma; beta-Galactosidase; Bucladesine; Cell Line; Colforsin; Colonic Neoplasms; Cyclic AMP; Dactinomycin; Electrophoresis, Polyacrylamide Gel; Enzyme Induction; Epithelium; Humans; Lactase; Lactase-Phlorizin Hydrolase; Methionine; Microvilli; Sucrase-Isomaltase Complex; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1994 |
Phorbol ester has different effects on forskolin and beta-adrenergic-stimulated cAMP accumulation in mouse parotid acini.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Animals; Colforsin; Cyclic AMP; Cytosol; In Vitro Techniques; Isoproterenol; Male; Membranes; Mice; Parotid Gland; Protein Kinase C; Signal Transduction; Tetradecanoylphorbol Acetate | 1993 |
Cyclic AMP increases the release of parathyroid hormone-related protein from a lung-cancer cell line.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Bucladesine; Calcitonin; Carcinoma, Squamous Cell; Cell Line; Colforsin; Cyclic AMP; Humans; Kinetics; Lung Neoplasms; Neoplasm Proteins; Parathyroid Hormone-Related Protein; Protein Biosynthesis; Proteins; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1994 |
Involvement of protein kinase A and C in the production of interleukin-1 alpha-induced prostaglandin E2 from mouse osteoblast-like cell line, MC3T3-E1.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 1-Methyl-3-isobutylxanthine; 3T3 Cells; 8-Bromo Cyclic Adenosine Monophosphate; Alkaloids; Animals; Carbazoles; Cyclic AMP-Dependent Protein Kinases; Cycloheximide; Dinoprostone; Humans; Indoles; Indomethacin; Interleukin-1; Isoquinolines; Kinetics; Mice; Osteoblasts; Piperazines; Protein Kinase C; Pyrroles; Recombinant Proteins; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate | 1994 |
Antiproliferative effect of prostaglandin E2 in cultured guinea pig tracheal smooth muscle cells.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Blood Physiological Phenomena; Cell Division; Cells, Cultured; Colforsin; Cyclic AMP; Dinoprostone; Guinea Pigs; Male; Muscle, Smooth; Tetradecanoylphorbol Acetate; Trachea | 1994 |
Modulation of normal human melanocyte dendricity by growth-promoting agents.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Bucladesine; Cattle; Cells, Cultured; Cyclic AMP; Dendrites; Fetal Blood; Fibroblast Growth Factor 2; Growth Substances; Hot Temperature; Humans; Melanocytes; Recombinant Proteins; Tetradecanoylphorbol Acetate | 1993 |
Second messenger activators regulate CCK mRNA in the human neuroepithelioma cell line SK-N-MCIXC.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Cell Line; Cholecystokinin; Exons; Gene Expression; Humans; Neuroectodermal Tumors, Primitive, Peripheral; Restriction Mapping; RNA, Messenger; Second Messenger Systems; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1994 |
Pituitary adenylate cyclase-activating polypeptide effects in pituitary cells: modulation by gonadotropin-releasing hormone in alpha T3-1 cells.
Topics: 1-Methyl-3-isobutylxanthine; Calcimycin; Cell Line; Cholera Toxin; Colforsin; Cyclic AMP; Enzyme Activation; Gonadotropin-Releasing Hormone; Neuropeptides; Pituitary Adenylate Cyclase-Activating Polypeptide; Pituitary Gland; Protein Kinase C; Signal Transduction; Tetradecanoylphorbol Acetate | 1994 |
Involvement of protein kinase C in cAMP regulation of myelin basic protein gene expression.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Base Sequence; Binding Sites; Cyclic AMP; Gene Expression Regulation; Molecular Sequence Data; Myelin Basic Protein; Neurilemmoma; Oligodeoxyribonucleotides; Peripheral Nervous System Neoplasms; Phorbol Esters; Promoter Regions, Genetic; Protein Kinase C; Proto-Oncogene Proteins c-jun; Rats; Recombinant Fusion Proteins; Regulatory Sequences, Nucleic Acid; Sequence Deletion; Signal Transduction; Stereoisomerism; Tetradecanoylphorbol Acetate; Transfection; Tumor Cells, Cultured | 1994 |
PTP-PEST: a protein tyrosine phosphatase regulated by serine phosphorylation.
Topics: 1-Methyl-3-isobutylxanthine; Baculoviridae; Colforsin; Cyclic AMP-Dependent Protein Kinases; Gene Expression Regulation, Enzymologic; HeLa Cells; Humans; Peptide Mapping; Phorbol Esters; Phosphopeptides; Phosphorylation; Protein Kinase C; Protein Tyrosine Phosphatase, Non-Receptor Type 12; Protein Tyrosine Phosphatases; Recombinant Proteins; Sequence Analysis; Serine; Tetradecanoylphorbol Acetate | 1994 |
Contribution of known mitogenic signaling pathways to induction of DNA synthesis in quiescent Chinese hamster fibroblasts.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Bucladesine; Cholera Toxin; Cricetinae; Cricetulus; Cyclic AMP; Epidermal Growth Factor; Fibroblasts; Insulin; Mitosis; Phosphorylation; Protein Kinase C; Protein-Tyrosine Kinases; Ribosomal Protein S6; Ribosomal Proteins; Signal Transduction; Tetradecanoylphorbol Acetate; Theophylline | 1994 |
The regulation of insulin-like growth factor-binding protein 1 messenger ribonucleic acid in cultured rat hepatocytes: the roles of glucagon and growth hormone.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Blotting, Northern; Carrier Proteins; Cells, Cultured; Cyclic AMP; Densitometry; Dexamethasone; Dose-Response Relationship, Drug; Enzyme Activation; Gene Expression Regulation; Glucagon; Growth Hormone; Insulin-Like Growth Factor Binding Protein 1; Liver; Male; Protein Kinase C; Rats; Rats, Sprague-Dawley; RNA, Messenger; Tetradecanoylphorbol Acetate; Time Factors | 1994 |
Transcriptional regulation of plasminogen activator inhibitor-1 expression in human synovial fibroblasts by prostaglandin E2: mediation by protein kinase A and role of interleukin-1.
Topics: 1-Methyl-3-isobutylxanthine; Blood; Cadaver; Cells, Cultured; Colforsin; Culture Media; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dinoprostone; Fibroblasts; Gene Expression Regulation; Humans; Interleukin-1; Plasminogen Activator Inhibitor 1; Protein Kinase Inhibitors; RNA, Messenger; Synovial Membrane; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1994 |
Effect of metabolic inhibitors and second messengers upon Na(+)-H+ exchange in the sheep cardiac Purkinje fibre.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine Triphosphate; Animals; Antimetabolites; Cyanides; Cyclic AMP; Deoxyglucose; Heart; Hydrogen-Ion Concentration; In Vitro Techniques; Luminescent Measurements; Microelectrodes; Myocardium; Purkinje Fibers; Second Messenger Systems; Sheep; Sodium-Hydrogen Exchangers; Tetradecanoylphorbol Acetate; Trifluoperazine | 1994 |
Phorbol ester activation of protein kinase C inhibits CNP-stimulated cyclic GMP production in the mouse AtT-20 pituitary tumour cell line.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Atrial Natriuretic Factor; Cell Line; Colforsin; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Activation; Kinetics; Mice; Natriuretic Peptide, C-Type; Pituitary Neoplasms; Protein Kinase C; Proteins; Tetradecanoylphorbol Acetate; Time Factors; Tumor Cells, Cultured | 1994 |
Modulation of cytokine expression in PB-3c mastocytes by IBMX and PMA.
Topics: 1-Methyl-3-isobutylxanthine; Actins; Alkaloids; Animals; Bone Marrow; Cell Line; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cytokines; Diglycerides; Enzyme Activation; Gene Expression; Genes, ras; Granulocyte-Macrophage Colony-Stimulating Factor; Interleukin-3; Interleukin-6; Mast Cells; Mice; Protein Kinase C; RNA, Messenger; Staurosporine; Tetradecanoylphorbol Acetate; Transfection | 1994 |
Distinct signaling pathways mediate phorbol-ester-induced and cytokine-induced inhibition of erythropoietin gene expression.
Topics: 1-Methyl-3-isobutylxanthine; Bucladesine; Carcinoma, Hepatocellular; Cell Hypoxia; Cyclic AMP; Cytokines; Erythropoietin; Gene Expression; Humans; Interleukin-1; Isoenzymes; Kinetics; Liver Neoplasms; Protein Kinase C; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1994 |
Regulation of riboflavin intestinal uptake by protein kinase A: studies with Caco-2 cells.
Topics: 1-Methyl-3-isobutylxanthine; Carrier Proteins; Cell Line; Colchicine; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cycloheximide; Dactinomycin; Humans; Intestinal Mucosa; Marine Toxins; Oxazoles; Protein Kinase C; Riboflavin; Tetradecanoylphorbol Acetate | 1994 |
Ultraviolet radiation-induced melanogenesis in human melanocytes. Effects of modulating protein kinase C.
Topics: 1-Methyl-3-isobutylxanthine; 3T3 Cells; Animals; Diglycerides; Enzyme Induction; Humans; Indoles; Intracellular Signaling Peptides and Proteins; Isoenzymes; Melanins; Melanocytes; Melanoma; Melanoma, Experimental; Membrane Proteins; Mice; Myristoylated Alanine-Rich C Kinase Substrate; Neoplasm Proteins; Phosphorylation; Protein Kinase C; Protein Processing, Post-Translational; Proteins; Signal Transduction; Skin Neoplasms; Taurodeoxycholic Acid; Tetradecanoylphorbol Acetate; Ultraviolet Rays | 1994 |
Study of the activation mechanism of adriamycin on rat mast cells.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Antimycin A; Benzalkonium Compounds; Calcium; Cells, Cultured; Cholera Toxin; Doxorubicin; Ethers, Cyclic; Histamine Release; In Vitro Techniques; Mast Cells; Okadaic Acid; Peritoneal Cavity; Pertussis Toxin; Pleura; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate; Trifluoperazine; Virulence Factors, Bordetella | 1994 |
Vasoactive intestinal polypeptide stimulates cyclic AMP production in mouse N1E-115 neuroblastoma cells: modulation by a protein kinase C activator and ionomycin.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 1-Methyl-3-isobutylxanthine; Animals; Calcium; Carcinogens; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Drug Interactions; Drug Synergism; Enzyme Activation; Ionomycin; Isoquinolines; Kinetics; Mice; Neuroblastoma; Phorbol Esters; Piperazines; Protein Kinase C; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Vasoactive Intestinal Peptide | 1994 |
Inhibition of muscarinic receptor-induced inositol phospholipid hydrolysis by caffeine, beta-adrenoceptors and protein kinase C in intestinal smooth muscle.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Bucladesine; Caffeine; Calcium Channels; Calcium-Transporting ATPases; Carbachol; Cyclic AMP; Diglycerides; Gallopamil; Guinea Pigs; Hydrolysis; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Intestine, Small; Isoproterenol; Muscle, Smooth; Protein Kinase C; Receptors, Adrenergic, beta; Receptors, Muscarinic; Ryanodine; Stereoisomerism; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin | 1995 |
Calcium efflux from cultured bovine adrenal chromaffin cells induced by pituitary adenylate cyclase-activating polypeptide (PACAP): possible involvement of an Na+/Ca2+ exchange mechanism.
Topics: 1-Methyl-3-isobutylxanthine; Adrenal Medulla; Amiloride; Animals; Calcium; Carrier Proteins; Cattle; Cells, Cultured; Colforsin; Cyclic AMP; Inositol Phosphates; Neuropeptides; Pituitary Adenylate Cyclase-Activating Polypeptide; Sodium-Calcium Exchanger; Tetradecanoylphorbol Acetate | 1995 |
O-methylation of L-dopa in melanin metabolism and the presence of catechol-O-methyltransferase in melanocytes.
Topics: 1-Methyl-3-isobutylxanthine; Catechol O-Methyltransferase; Cells, Cultured; Humans; Isoenzymes; Levodopa; Melanins; Melanocytes; Melanoma; Membrane Proteins; Methylation; Microscopy, Immunoelectron; Monophenol Monooxygenase; Neoplasm Proteins; Subcellular Fractions; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1994 |
Hormonal regulation of tissue-type plasminogen activator and plasminogen activator inhibitor type-1 in cultured monkey Sertoli cells.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Bucladesine; Cells, Cultured; Colforsin; Cyclic AMP; Follicle Stimulating Hormone; Gonadotropin-Releasing Hormone; Hormones; Macaca mulatta; Male; Plasminogen Activator Inhibitor 1; RNA Probes; RNA, Messenger; Sertoli Cells; Tetradecanoylphorbol Acetate; Tissue Plasminogen Activator | 1995 |
Stimulation of cultured melanocytes in medium containing a serum substitute: Ultroser-G.
Topics: 1-Methyl-3-isobutylxanthine; alpha-MSH; Animals; Blood; Blood Substitutes; Bucladesine; Cattle; Cell Division; Cells, Cultured; Cholera Toxin; Culture Media; Fibroblast Growth Factor 2; Humans; Leukotriene C4; Leukotriene D4; Male; Melanocytes; Organic Chemicals; Skin; Tetradecanoylphorbol Acetate | 1995 |
Inhibition of gap junctional communication by polyunsaturated fatty acids in WB cells: evidence that connexin 43 is not hyperphosphorylated.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Cell Communication; Cell Line; Connexin 43; Cyclic AMP; Fatty Acids, Unsaturated; Gap Junctions; Isoenzymes; Isoproterenol; Isoquinolines; Liver; Phosphorylation; Protein Kinase C; Protein-Tyrosine Kinases; Rats; Rats, Inbred F344; Structure-Activity Relationship; Tetradecanoylphorbol Acetate | 1995 |
Study of the activation mechanism of human GRF(1-29)NH2 on rat mast cell histamine release.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Calcium; Cell Division; Cholera Toxin; Cyclic AMP; Dose-Response Relationship, Drug; Drug Interactions; GTP-Binding Proteins; Histamine Release; Humans; Mast Cells; Peritoneum; Pertussis Toxin; Pleura; Rats; Rats, Sprague-Dawley; Sermorelin; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1995 |
Stimulation of Na+/H+ exchange activity by endothelin in opossum kidney cells.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Cells, Cultured; Cyclic AMP; Dogs; Endothelins; Enzyme Inhibitors; Ion Transport; Kidney Tubules, Proximal; Naphthalenes; Opossums; Parathyroid Hormone; Protein Kinase C; Sodium-Hydrogen Exchangers; Tetradecanoylphorbol Acetate | 1995 |
Regulation of lysophosphatidic acid-stimulated tyrosine phosphorylation of pp42 mitogen-activated protein kinase by protein kinase C and protein kinase A in EAhy926 cells.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Endothelium, Vascular; Indoles; Isoenzymes; Lysophospholipids; Phosphorylation; Phosphotyrosine; Protein Kinase C; Tetradecanoylphorbol Acetate; Tyrosine | 1995 |
Inhibition of serine/threonine protein phosphatases enhances agonist-stimulated cAMP accumulation in UMR 106 osteoblast-like cells.
Topics: 1-Methyl-3-isobutylxanthine; Antifungal Agents; Colforsin; Cyclic AMP; Dinoprostone; Ethers, Cyclic; Humans; Kinetics; Marine Toxins; Okadaic Acid; Osteoblasts; Oxazoles; Parathyroid Hormone; Parathyroid Hormone-Related Protein; Protein Serine-Threonine Kinases; Proteins; Pyrans; Spiro Compounds; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1995 |
Cyclic AMP-increasing agents interfere with chemoattractant-induced respiratory burst in neutrophils as a result of the inhibition of phosphatidylinositol 3-kinase rather than receptor-operated Ca2+ influx.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Arachidonic Acid; Biological Transport, Active; Calcium; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Guinea Pigs; In Vitro Techniques; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphatidylinositol 3-Kinases; Phosphotransferases (Alcohol Group Acceptor); Receptors, Formyl Peptide; Receptors, Immunologic; Receptors, Peptide; Respiratory Burst; Signal Transduction; Superoxides; Tetradecanoylphorbol Acetate | 1995 |
Induction of Ca2+/calmodulin-stimulated cyclic AMP phosphodiesterase (PDE1) activity in Chinese hamster ovary cells (CHO) by phorbol 12-myristate 13-acetate and by the selective overexpression of protein kinase C isoforms.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Base Sequence; Brain; CHO Cells; Cricetinae; Cyclic Nucleotide Phosphodiesterases, Type 1; DNA Primers; Enzyme Induction; Gene Expression; Isoenzymes; Kinetics; Mice; Molecular Sequence Data; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Polymerase Chain Reaction; Protein Kinase C; Rats; Recombinant Proteins; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transfection | 1995 |
Mitogen-activated protein kinase pathway and AP-1 are activated during cAMP-induced melanogenesis in B-16 melanoma cells.
Topics: 1-Methyl-3-isobutylxanthine; Affinity Labels; alpha-MSH; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cell Nucleus; Cyclic AMP; Enzyme Activation; Gene Expression; MAP Kinase Kinase Kinase 1; Melanins; Melanoma, Experimental; Mice; Microscopy, Confocal; Mitogen-Activated Protein Kinase Kinases; Monophenol Monooxygenase; Phosphodiesterase Inhibitors; Protein Kinases; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-jun; Proto-Oncogene Proteins c-raf; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription Factor AP-1 | 1995 |
Cell-to-cell contact via measles virus haemagglutinin-CD46 interaction triggers CD46 downregulation.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Antibodies, Viral; Antigens, CD; Bucladesine; Cell Communication; Cell Line; Colforsin; Cyclic AMP-Dependent Protein Kinases; Down-Regulation; Enzyme Activation; Hemagglutinins, Viral; Humans; Measles virus; Membrane Cofactor Protein; Membrane Glycoproteins; Mice; Phosphodiesterase Inhibitors; Protein Kinase C; Receptors, Virus; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1995 |
Intracellular mechanisms of cytoplasmic Ca2+ oscillation in rat megakaryocyte.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine Triphosphate; Alkaloids; Animals; Calcimycin; Calcium; Calcium-Transporting ATPases; Calmodulin; Colforsin; Cyclic AMP; Cytoplasm; Egtazic Acid; Female; Guanosine 5'-O-(3-Thiotriphosphate); In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Kinetics; Male; Megakaryocytes; Models, Biological; Oscillometry; Protein Kinase C; Rats; Staurosporine; Sulfonamides; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin; Trifluoperazine | 1993 |
Activation of protein kinase C partially alleviates noradrenaline inhibition of insulin secretion.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Bucladesine; Cyclic AMP; Enzyme Activation; Glucose; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Norepinephrine; Protein Kinase C; Rats; Rats, Wistar; Tetradecanoylphorbol Acetate; Thionucleotides | 1993 |
Protein kinase C regulation of prolactin gene expression in lactotroph cells: involvement in dopamine inhibition.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Bromocriptine; Cells, Cultured; Colforsin; Cyclic AMP; Dopamine; Dose-Response Relationship, Drug; Female; Gene Expression Regulation; Kinetics; Nifedipine; Pituitary Gland, Anterior; Potassium; Prolactin; Protein Kinase C; Rats; Rats, Sprague-Dawley; RNA, Messenger; Tetradecanoylphorbol Acetate; Time Factors | 1993 |
Diacylglycerol kinase is phosphorylated in vivo upon stimulation of the epidermal growth factor receptor and serine/threonine kinases, including protein kinase C-epsilon.
Topics: 1-Methyl-3-isobutylxanthine; Antibodies, Monoclonal; Antibody Specificity; Cells, Cultured; Colforsin; Diacylglycerol Kinase; Epidermal Growth Factor; Epitopes; ErbB Receptors; Escherichia coli; Humans; Peptide Mapping; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotransferases; Phosphotyrosine; Protein Kinase C; Protein Kinases; Protein Serine-Threonine Kinases; Recombinant Proteins; Tetradecanoylphorbol Acetate; Transfection; Tyrosine | 1993 |
Divergent actions of prostaglandins-E2 and -F2 alpha on the regulation of insulin-like growth factor-binding protein-3 in luteinized granulosa cells.
Topics: 1-Methyl-3-isobutylxanthine; Analysis of Variance; Animals; Bucladesine; Carrier Proteins; Cells, Cultured; Cyclic AMP; Dinoprost; Dinoprostone; Female; Granulosa Cells; Insulin-Like Growth Factor Binding Protein 4; Insulin-Like Growth Factor Binding Proteins; Insulin-Like Growth Factor II; Progesterone; Swine; Tetradecanoylphorbol Acetate | 1993 |
Phorbol ester stimulation of the type I and type III adenylyl cyclases in whole cells.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Animals; Cell Line; Colforsin; Enzyme Activation; Gene Library; Humans; Isoenzymes; Kidney; Kinetics; Rats; Recombinant Proteins; Tetradecanoylphorbol Acetate; Transfection | 1993 |
Bicarbonate induces sensitization of cyclic AMP accumulation by intact 1321N1 human astrocytoma cells.
Topics: 1-Methyl-3-isobutylxanthine; Astrocytoma; Bicarbonates; Blood Physiological Phenomena; Colforsin; Cyclic AMP; Humans; Magnesium; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1993 |
Synergistic activation of estrogen receptor-mediated transcription by estradiol and protein kinase activators.
Topics: 1-Methyl-3-isobutylxanthine; Animals; CHO Cells; Cholera Toxin; Cricetinae; DNA-Binding Proteins; Drug Synergism; Estradiol; Estrogen Antagonists; Gene Expression Regulation; Humans; Plasmids; Polyunsaturated Alkamides; Promoter Regions, Genetic; Protein Kinases; Receptors, Estrogen; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transcriptional Activation; Transfection; Tumor Cells, Cultured; Vitellogenins | 1993 |
Protein kinase C activates chloride conductance in C127 cells stably expressing the cystic fibrosis gene.
Topics: 1-Methyl-3-isobutylxanthine; 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Cell Line; Chloride Channels; Chlorides; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Humans; Ion Channels; Kinetics; Membrane Proteins; Mice; Protein Kinase C; Protein Kinases; Tetradecanoylphorbol Acetate; Transfection | 1993 |
Pancreatic acini possess endothelin receptors whose internalization is regulated by PLC-activating agents.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Amylases; Animals; Benzodiazepinones; Bombesin; Calcimycin; Carbachol; Cholecystokinin; Cyclic AMP; Devazepide; Endothelins; Enzyme Activation; In Vitro Techniques; Kinetics; Male; Pancreas; Rats; Rats, Sprague-Dawley; Receptors, Endothelin; Secretin; Sincalide; Tetradecanoylphorbol Acetate; Type C Phospholipases; Vasoactive Intestinal Peptide | 1993 |
Studies of human uveal melanocytes in vitro: growth regulation of cultured human uveal melanocytes.
Topics: 1-Methyl-3-isobutylxanthine; Adult; Aged; Blood; Cell Division; Cell Survival; Cells, Cultured; Cholera Toxin; Culture Media; Fibroblast Growth Factor 2; Growth Substances; Humans; Melanocytes; Middle Aged; Tetradecanoylphorbol Acetate; Uvea | 1993 |
Regulated expression of an intestinal mucin gene in HT29 colonic carcinoma cells.
Topics: 1-Methyl-3-isobutylxanthine; Adenocarcinoma; Bucladesine; Calcimycin; Colforsin; Colonic Neoplasms; DNA Probes; Ethers, Cyclic; Gene Expression Regulation, Neoplastic; Humans; Intestinal Mucosa; Ionomycin; Ionophores; Kinetics; Mucins; Okadaic Acid; RNA, Messenger; RNA, Neoplasm; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Cells, Cultured | 1993 |
Analysis of fra-2 gene expression.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Base Sequence; Calcimycin; Cells, Cultured; Chick Embryo; Chickens; Chloramphenicol O-Acetyltransferase; Cholera Toxin; Cyclic AMP; Dinucleoside Phosphates; DNA-Binding Proteins; Enhancer Elements, Genetic; Fibroblasts; Fos-Related Antigen-2; Gene Expression Regulation; Genes, fos; Molecular Sequence Data; Oligodeoxyribonucleotides; Promoter Regions, Genetic; Recombinant Fusion Proteins; RNA, Messenger; Sequence Deletion; TATA Box; Tetradecanoylphorbol Acetate; Transcription Factors; Transcription, Genetic; Transfection | 1993 |
Protein kinase C activation and positive and negative agonist regulation of 3',5'-cyclic adenosine monophosphate levels in cultured rat Sertoli cells.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Cells, Cultured; Cyclic AMP; Dose-Response Relationship, Drug; Enzyme Activation; Follicle Stimulating Hormone; Glucagon; Isoproterenol; Male; Phenylisopropyladenosine; Protein Kinase C; Rats; Sertoli Cells; Tetradecanoylphorbol Acetate | 1993 |
Regulation of two forms of the TNF receptors by phorbol ester and dibutyryl cyclic adenosine 3',5'-monophosphate in human histiocytic lymphoma cell line U-937.
Topics: 1-Methyl-3-isobutylxanthine; Bucladesine; Butyrates; Butyric Acid; Colforsin; Humans; Kinetics; Molecular Weight; Receptors, Cell Surface; Receptors, Tumor Necrosis Factor; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1993 |
Interleukin-1-inducible expression of gro-beta via NF-kappa B activation is dependent upon tyrosine kinase signaling.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Base Sequence; Cell Line; Chemokine CXCL1; Chemokines, CXC; Chemotactic Factors; Colforsin; Cytomegalovirus; Gene Expression; Gene Expression Regulation, Neoplastic; Genes, jun; Genes, myc; Genistein; Growth Substances; HeLa Cells; Humans; Intercellular Signaling Peptides and Proteins; Interleukin-1; Isoflavones; L Cells; Melanoma; Mice; Molecular Sequence Data; NF-kappa B; Oligonucleotide Probes; Promoter Regions, Genetic; Protein-Tyrosine Kinases; Recombinant Proteins; Signal Transduction; Tetradecanoylphorbol Acetate; Transcriptional Activation; Transfection; Tumor Cells, Cultured | 1993 |
Lindane decreases forskolin-stimulated cyclic AMP accumulation but does not modify Gs in rat enterocytes.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine Diphosphate Ribose; Adenylyl Cyclases; Animals; Autoradiography; Cell Membrane; Cholera Toxin; Colforsin; Cyclic AMP; GTP-Binding Proteins; Guanylyl Imidodiphosphate; Hexachlorocyclohexane; Intestinal Mucosa; Jejunum; Kinetics; Male; Membrane Proteins; Phorbol Esters; Phosphorus Radioisotopes; Rats; Rats, Wistar; Tetradecanoylphorbol Acetate; Vasoactive Intestinal Peptide | 1993 |
Neurohormonal regulation of histamine release from isolated rabbit fundic mucosal cells.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Bucladesine; Calcimycin; Carbachol; Colforsin; Diglycerides; Dose-Response Relationship, Drug; Gastric Fundus; Gastric Mucosa; Gastrins; Histamine Release; Male; Muscarinic Antagonists; Prostaglandins; Rabbits; Sincalide; Somatostatin; Tetradecanoylphorbol Acetate | 1993 |
Modulation of cell signaling pathways can enhance or impair glucocorticoid-induced gene expression without altering the state of receptor phosphorylation.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Breast Neoplasms; Chloramphenicol O-Acetyltransferase; Colforsin; Dexamethasone; Ethers, Cyclic; Female; Gene Expression; Gene Expression Regulation, Neoplastic; Genetic Vectors; Humans; Luciferases; Mammary Tumor Virus, Mouse; Okadaic Acid; Phosphopeptides; Phosphorylation; Promoter Regions, Genetic; Protein Tyrosine Phosphatases; Receptors, Glucocorticoid; Recombinant Proteins; Signal Transduction; Tetradecanoylphorbol Acetate; Transfection; Tumor Cells, Cultured | 1993 |
Prostaglandin E2 and other cyclic AMP elevating agents inhibit interleukin 2 gene transcription by counteracting calcineurin-dependent pathways.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Calcineurin; Calmodulin-Binding Proteins; Cell Line; Chloramphenicol O-Acetyltransferase; Colforsin; Cyclic AMP; Dinoprostone; Gene Deletion; Gene Expression; Humans; Interleukin-2; Ionomycin; Kinetics; Mice; Phosphoprotein Phosphatases; Plasmids; Polymerase Chain Reaction; Promoter Regions, Genetic; Protein Kinase C; T-Lymphocytes; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transfection; Tumor Cells, Cultured | 1993 |
Forskolin and phorbol myristate acetate inhibit intracellular Ca2+ mobilization induced by amitriptyline and bradykinin in rat frontocortical neurons.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 1-Methyl-3-isobutylxanthine; Amitriptyline; Animals; Bradykinin; Bucladesine; Calcium; Cells, Cultured; Colforsin; Cyclic AMP; Frontal Lobe; Imipramine; Inositol 1,4,5-Trisphosphate; Isoquinolines; Kinetics; Neurons; Piperazines; Protein Kinase Inhibitors; Rats; Tetradecanoylphorbol Acetate | 1993 |
Selection of alternative G-mediated signaling pathways at the dopamine D2 receptor by protein kinase C.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Alkaloids; Animals; Arachidonic Acid; Calcimycin; Calcium; CHO Cells; Colforsin; Cricetinae; Cyclic AMP; Diglycerides; Diterpenes; Dopamine D2 Receptor Antagonists; Ergolines; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Kinetics; Protein Kinase C; Quinpirole; Raclopride; Receptors, Dopamine D2; Recombinant Proteins; Salicylamides; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate; Transfection | 1993 |
Indirect inhibition by bradykinin of cyclic AMP generation in isolated rat glomeruli and mesangial cells.
Topics: 1-Methyl-3-isobutylxanthine; Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Bradykinin; Cells, Cultured; Colforsin; Cyclic AMP; Diglycerides; Dinoprostone; Down-Regulation; Drug Interactions; Enzyme Activation; Glomerular Mesangium; Isoproterenol; Kidney Glomerulus; Male; Pertussis Toxin; Protein Kinase C; Quinacrine; Rats; Rats, Sprague-Dawley; Receptors, Bradykinin; Stimulation, Chemical; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1993 |
Dissociation of KATP channel and sulphonylurea receptor in the rat clonal insulin-secreting cell line, CRI-D11.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine Triphosphate; Animals; ATP-Binding Cassette Transporters; Cell Membrane; Clone Cells; Glyburide; Insulin; Insulin Secretion; Insulinoma; Membrane Potentials; Pancreatic Neoplasms; Potassium; Potassium Channels; Potassium Channels, Inwardly Rectifying; Rats; Receptors, Drug; Sulfonylurea Receptors; Tetradecanoylphorbol Acetate; Tolbutamide; Tumor Cells, Cultured | 1993 |
Regulation of CCK mRNA in the human neuroepithelioma cell line SK-N-MCIXC in response to second messenger activators.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Cell Line; Cholecystokinin; Cyclic AMP; Dimethyl Sulfoxide; Gene Expression Regulation; Humans; Kinetics; Neuroectodermal Tumors, Primitive, Peripheral; Protein Kinase C; RNA, Messenger; Second Messenger Systems; Tetradecanoylphorbol Acetate | 1993 |
Activation of mitogen-activated protein kinases by stimulation of the central cannabinoid receptor CB1.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Adenylate Cyclase Toxin; Analgesics; Animals; Benzoquinones; Bucladesine; Calcium-Calmodulin-Dependent Protein Kinases; Cannabinoids; Cell Line; CHO Cells; Cricetinae; Cyclohexanols; DNA-Binding Proteins; Early Growth Response Protein 1; Enzyme Activation; Enzyme Inhibitors; GTP-Binding Proteins; Humans; Immediate-Early Proteins; Kinetics; Lactams, Macrocyclic; Pertussis Toxin; Piperidines; Pyrazoles; Quinones; Receptors, Cannabinoid; Receptors, Drug; Recombinant Proteins; Rifabutin; Rimonabant; Tetradecanoylphorbol Acetate; Transcription Factors; Transfection; Virulence Factors, Bordetella | 1995 |
Down-regulation and differential restoration of cAMP responses upon transient phorbol ester treatment of primary osteoblastic cells.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Animals; Cells, Cultured; Colforsin; Cyclic AMP; Dinoprostone; Down-Regulation; Enzyme Activation; Kinetics; Osteoblasts; Parathyroid Hormone; Phorbol Esters; Phosphodiesterase Inhibitors; Protein Kinase C; Rats; Receptors, Parathyroid Hormone; Signal Transduction; Skull; Tetradecanoylphorbol Acetate | 1995 |
Induction of intercellular adhesion molecule-1 by tumor necrosis factor-alpha through the 55-kDa receptor is dependent on protein kinase C in human retinal pigment epithelial cells.
Topics: 1-Methyl-3-isobutylxanthine; Carcinogens; Cell Line, Transformed; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Flow Cytometry; Humans; Intercellular Adhesion Molecule-1; Isoquinolines; Naphthalenes; Pigment Epithelium of Eye; Protein Kinase C; Receptors, Tumor Necrosis Factor; Second Messenger Systems; Signal Transduction; Simian virus 40; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1996 |
Modulation of prohormone convertase mRNA by second messenger activators and drugs.
Topics: 1-Methyl-3-isobutylxanthine; Amino Acid Sequence; Animals; Blotting, Northern; Cell Line; Cyclic AMP; Furin; Gene Expression; Humans; Molecular Sequence Data; Protein Kinase C; Rats; RNA, Messenger; Second Messenger Systems; Substrate Specificity; Subtilisins; Tetradecanoylphorbol Acetate; Thyroid Neoplasms; Tumor Cells, Cultured | 1996 |
The actions of prostaglandin E2 on potassium currents in rat tail artery vascular smooth muscle cells: regulation by protein kinase A and protein kinase C.
Topics: 1-Methyl-3-isobutylxanthine; Alkaloids; Animals; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dinoprostone; Male; Muscle, Smooth, Vascular; Potassium Channels; Protein Kinase C; Rats; Rats, Sprague-Dawley; Signal Transduction; Staurosporine; Tail; Tetradecanoylphorbol Acetate | 1996 |
Protein kinase C modulates natriuretic peptide receptors in astroglial cultures from rat brain.
Topics: 1-Methyl-3-isobutylxanthine; Alkaloids; Animals; Animals, Newborn; Astrocytes; Atrial Natriuretic Factor; Binding Sites; Brain Stem; Cells, Cultured; Colforsin; Cyclic GMP; Down-Regulation; Enzyme Inhibitors; Hypothalamus; Kinetics; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptors, Atrial Natriuretic Factor; Staurosporine; Tetradecanoylphorbol Acetate; Up-Regulation | 1996 |
Activation of the cAMP-dependent signaling pathway downregulates the expression of interleukin-3 and granulocyte-macrophage colony-stimulating factor in activated human T lymphocytes.
Topics: 1-Methyl-3-isobutylxanthine; Bucladesine; Cells, Cultured; Concanavalin A; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dinoprostone; Drug Synergism; Gene Expression Regulation; Granulocyte-Macrophage Colony-Stimulating Factor; Half-Life; Humans; Interleukin-3; Isoproterenol; Lymphocyte Activation; RNA, Messenger; Signal Transduction; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1996 |
The proteinase-activated receptor 2 is induced by inflammatory mediators in human endothelial cells. Comparison with the thrombin receptor.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Blotting, Northern; Cell Adhesion Molecules; Cell Line; Cells, Cultured; Chlorocebus aethiops; Colforsin; DNA Probes; Down-Regulation; Endothelium, Vascular; Humans; Inflammation; Interleukin-1; Kinetics; Lipopolysaccharides; Receptor, PAR-2; Receptors, Cell Surface; Receptors, Thrombin; Recombinant Proteins; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transfection; Tumor Necrosis Factor-alpha; Umbilical Veins | 1996 |
Mitoxantrone induces nonimmunological histamine release from rat mast cells.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Antineoplastic Agents; Calcium; Carcinogens; Cell Division; Cyclic AMP; Drug Interactions; Enzyme Inhibitors; Ethers, Cyclic; Exocytosis; Histamine Release; Mast Cells; Mitoxantrone; Okadaic Acid; p-Methoxy-N-methylphenethylamine; Peritoneal Cavity; Phosphodiesterase Inhibitors; Pleura; Rats; Rats, Sprague-Dawley; Signal Transduction; Tetradecanoylphorbol Acetate; Theophylline; Trifluoperazine | 1996 |
Differential effect of the activation of protein kinase A on the protein synthesis and secretion in the T-helper 2 cell line D10.G4.1.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Cell Line; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Humans; Interleukin-10; Interleukin-4; Mice; Mice, Inbred C3H; Rabbits; Rats; Receptors, Antigen, T-Cell; RNA, Messenger; Tetradecanoylphorbol Acetate; Th2 Cells; Type C Phospholipases | 1996 |
Effects of parathyroid hormone and agonists of the adenylyl cyclase and protein kinase C pathways on bone cell proliferation.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Amino Acid Sequence; Animals; Cell Division; Cells, Cultured; Colforsin; Culture Techniques; Enzyme Activation; Mice; Mice, Inbred ICR; Molecular Sequence Data; Osteoblasts; Parathyroid Hormone; Peptide Fragments; Protein Kinase C; Signal Transduction; Teriparatide; Tetradecanoylphorbol Acetate | 1996 |
PMA and ionomycin differently affect atrial natriuretic peptide stimulated cyclic GMP production in rat mesangial cells.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Atrial Natriuretic Factor; Cyclic GMP; Enzyme Activation; Glomerular Mesangium; Ionomycin; Ionophores; Male; Phosphodiesterase Inhibitors; Protein Kinase C; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate | 1996 |
Paradoxical effect of 3-isobutyl-1-methylxanthine on cytochrome P450 cholesterol side-chain cleavage mRNA accumulation in porcine granulosa cells.
Topics: 1-Methyl-3-isobutylxanthine; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Animals; Cells, Cultured; Cholesterol Side-Chain Cleavage Enzyme; Cyclic AMP; Female; Follicle Stimulating Hormone; Granulosa Cells; Progesterone; RNA, Messenger; Swine; Tetradecanoylphorbol Acetate | 1996 |
The Ca(2+)-induced leak current in Xenopus oocytes is indeed mediated through a Cl- channel.
Topics: 1-Methyl-3-isobutylxanthine; 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; Adenosine Triphosphate; Animals; Calcium; Cell Membrane Permeability; Chloride Channels; Cholera Toxin; Cyclic AMP; Cytochalasin D; Cytoskeleton; Flufenamic Acid; Membrane Potentials; Oocytes; Oogenesis; ortho-Aminobenzoates; Patch-Clamp Techniques; Pertussis Toxin; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella; Xenopus laevis | 1995 |
Inhibition of human neutrophil binding to hydrogen peroxide-treated endothelial cells by cAMP and hydroxyl radical scavengers.
Topics: 1-Methyl-3-isobutylxanthine; Analysis of Variance; Bucladesine; Cell Adhesion; Cells, Cultured; Cyclic AMP; Deferoxamine; Endothelium, Vascular; Free Radical Scavengers; Glutathione; Humans; Hydrogen Peroxide; Hydroxyl Radical; Hypoxanthine; Isoproterenol; Neutrophils; Pentoxifylline; Tetradecanoylphorbol Acetate; Thrombin; Transferrin; Umbilical Veins; Xanthine Oxidase | 1996 |
Substance P activates the release of histamine from human skin mast cells through a pertussis toxin-sensitive and protein kinase C-dependent mechanism.
Topics: 1-Methyl-3-isobutylxanthine; Antibodies, Anti-Idiotypic; Bryostatins; Cyclic AMP; Enzyme Activation; Genistein; GTP-Binding Proteins; Histamine Release; Humans; Immunoglobulin E; In Vitro Techniques; Isoflavones; Lactones; Macrolides; Mast Cells; Pertussis Toxin; Protease Inhibitors; Protein Kinase C; Skin; Skin Physiological Phenomena; Substance P; Sulfones; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1996 |
Differential modulation of prohormone convertase mRNA by second messenger activators in two cholecystokinin-producing cell lines.
Topics: 1-Methyl-3-isobutylxanthine; Amino Acid Sequence; Binding Sites; Carcinogens; Cell Line; Cholecystokinin; Cyclic AMP; Furin; Gene Expression Regulation, Enzymologic; Molecular Sequence Data; Phosphodiesterase Inhibitors; Protein Kinase C; Proteins; RNA, Messenger; Second Messenger Systems; Subtilisins; Tetradecanoylphorbol Acetate | 1996 |
Modulation of islet G-proteins, alpha-glucosidehydrolase inhibition and insulin release stimulated by various secretagogues.
Topics: 1-Deoxynojirimycin; 1-Methyl-3-isobutylxanthine; Adenylate Cyclase Toxin; Adenylyl Cyclases; Adrenergic alpha-Agonists; Animals; Cholera Toxin; Clonidine; Colforsin; Enzyme Inhibitors; Female; Glucosamine; Glucose; Glycoside Hydrolases; GTP-Binding Proteins; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Mannoheptulose; Mice; Pertussis Toxin; Phosphodiesterase Inhibitors; Protein Kinase C; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1996 |
Inhibition of p70/p85 S6 kinase activities in T cells by dexamethasone.
Topics: 1-Methyl-3-isobutylxanthine; Administration, Topical; Animals; Anti-Inflammatory Agents; Colforsin; Dexamethasone; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glucocorticoids; Interleukin-2; Marine Toxins; Mice; Oxazoles; Phorbol Esters; Phosphatidylinositol 3-Kinases; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Polyenes; Protein Kinase C; Protein Serine-Threonine Kinases; Ribosomal Protein S6 Kinases; RNA, Messenger; Sirolimus; T-Lymphocytes; Tacrolimus; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1996 |
Homologous regulation of the rat C1a calcitonin receptor (CTR) in nonosteoclastic cells is independent of CTR messenger ribonucleic acid changes and cyclic adenosine 3',5'-monophosphate-dependent protein kinase activation.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Adenylyl Cyclases; Animals; Calcitonin; Cell Line; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Down-Regulation; Enzyme Activation; Humans; Kidney; Kinetics; Osteosarcoma; Polymerase Chain Reaction; Promoter Regions, Genetic; Rats; Receptors, Calcitonin; Recombinant Proteins; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transfection; Tumor Cells, Cultured | 1996 |
Multiple signal transduction pathways regulate clusterin (gp 80) gene expression in MDCK cells.
Topics: 1-Methyl-3-isobutylxanthine; Aldosterone; Alkaloids; Animals; Benzophenanthridines; Cell Line; Clusterin; Cyclic AMP; Dexamethasone; Dogs; Enzyme Inhibitors; Epidermal Growth Factor; Epithelium; Glycoproteins; Kidney; Kinetics; Molecular Chaperones; Phenanthridines; Progesterone; Protein Kinase C; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1996 |
Classical second messengers are not involved in proteinase-induced degranulation of airway gland cells.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Bradykinin; Calcimycin; Calcium; Cathepsins; Cattle; Cells, Cultured; Chymases; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Histamine; Leukocyte Elastase; Protein Kinase C; Second Messenger Systems; Serine Endopeptidases; Tetradecanoylphorbol Acetate; Trachea | 1996 |
Regulation of glycosylphosphatidylinositol-specific phospholipase D secretion from beta TC3 cells.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Carbachol; Cycloheximide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Immunohistochemistry; Insulin; Insulin Secretion; Insulinoma; Islets of Langerhans; Kinetics; Mice; Pancreatic Neoplasms; Peptide Fragments; Phospholipase D; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1997 |
Tyrosine kinase inhibition decreases Muc-1 expression in mouse epithelial cells.
Topics: 1-Methyl-3-isobutylxanthine; Amino Acid Sequence; Animals; Antibodies; Base Sequence; Cell Line; Cells, Cultured; Conserved Sequence; DNA Primers; Enzyme Inhibitors; Epithelium; Female; Gene Expression; Genistein; Isoflavones; Isoquinolines; Kinetics; Mammary Glands, Animal; Mice; Molecular Sequence Data; Mucin-1; Naphthalenes; Peptide Fragments; Polymerase Chain Reaction; Pregnancy; Protein Biosynthesis; Protein-Tyrosine Kinases; Recombinant Fusion Proteins; RNA, Messenger; Staurosporine; Sulfonamides; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transfection; Uterus | 1997 |
Effect of the protein phosphatase inhibitor okadaic acid on FSH-induced granulosa cell steroidogenesis.
Topics: 1-Methyl-3-isobutylxanthine; 3-Hydroxysteroid Dehydrogenases; Animals; Bucladesine; Cells, Cultured; Cholera Toxin; Colforsin; Cyclic AMP; Enzyme Activation; Female; Follicle Stimulating Hormone; Granulosa Cells; Okadaic Acid; Phosphoprotein Phosphatases; Progesterone; Protein Kinase C; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate | 1997 |
Apical and basolateral expression of aquaporin-1 in transfected MDCK and LLC-PK cells and functional evaluation of their transcellular osmotic water permeabilities.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Aquaporin 1; Aquaporins; Blotting, Northern; Blotting, Southern; Cell Membrane Permeability; Dogs; Immunoblotting; Ion Channels; Kidney; LLC-PK1 Cells; Microscopy, Immunoelectron; Osmolar Concentration; Phosphodiesterase Inhibitors; RNA, Messenger; Swine; Tetradecanoylphorbol Acetate; Transfection | 1997 |
Protein kinase A-dependent stimulation of exocytosis in mouse pancreatic beta-cells by glucose-dependent insulinotropic polypeptide.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Calcium; Cell Membrane; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Electric Conductivity; Enzyme Inhibitors; Exocytosis; Gastric Inhibitory Polypeptide; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Islets of Langerhans; Membrane Potentials; Mice; Mice, Inbred Strains; Peptide Fragments; Phosphodiesterase Inhibitors; Tetradecanoylphorbol Acetate; Thionucleotides | 1997 |
Adenosine stimulation of DNA synthesis in human endothelial cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 1-Methyl-3-isobutylxanthine; Adenosine; Adenosine Triphosphate; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; DNA; Endothelium, Vascular; Humans; Kinetics; Poly A; Purinergic P1 Receptor Antagonists; Quinazolines; Tetradecanoylphorbol Acetate; Thioinosine; Thionucleotides; Thymidine; Triazoles; Umbilical Veins | 1997 |
Protein kinase C and protein kinase A inhibit calcium-dependent but not stress-dependent c-Jun N-terminal kinase activation in rat liver epithelial cells.
Topics: 1-Methyl-3-isobutylxanthine; Androstadienes; Angiotensin II; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Enzyme Inhibitors; Epidermal Growth Factor; Epithelial Cells; Epithelium; Humans; JNK Mitogen-Activated Protein Kinases; Kinetics; Liver; Mitogen-Activated Protein Kinases; Models, Biological; Polyenes; Protein Kinases; Rats; Recombinant Proteins; Signal Transduction; Sirolimus; Tetradecanoylphorbol Acetate; Thapsigargin; Wortmannin | 1997 |
Insulin and insulin-like growth factor 1 antagonize the stimulation of ob gene expression by dexamethasone in cultured rat adipose tissue.
Topics: 1-Methyl-3-isobutylxanthine; Adipose Tissue; Animals; Cyclic AMP; Cycloheximide; Dexamethasone; Energy Metabolism; Enzyme Induction; Epididymis; Fatty Acid Synthases; Fatty Acids; Gene Expression Regulation; Glucose; Glucose Transporter Type 4; Insulin; Insulin-Like Growth Factor I; Lactic Acid; Leptin; Male; Microbodies; Monosaccharide Transport Proteins; Muscle Proteins; Organ Culture Techniques; Protein Biosynthesis; Protein Synthesis Inhibitors; Proteins; Pyruvic Acid; Rats; Rats, Wistar; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate; Transcription Factors | 1997 |
Mitogen-activated protein kinases mediate the stimulation of bile acid secretion by tauroursodeoxycholate in rat liver.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Bucladesine; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Colforsin; Enzyme Activation; Enzyme Inhibitors; Flavonoids; GTP-Binding Proteins; Indoles; Isomerism; Isoproterenol; Kinetics; Liver; Male; Maleimides; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Models, Biological; Protein Kinase C; Protein-Tyrosine Kinases; Rats; Rats, Wistar; Signal Transduction; Taurochenodeoxycholic Acid; Taurocholic Acid; Tetradecanoylphorbol Acetate | 1997 |
Inhibitory effect of 2-phenyl-4-quinolone on serotonin-mediated changes in the morphology and permeability of endothelial monolayers.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Biological Transport; Cattle; Cell Size; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic GMP; Endothelium; Enzyme Inhibitors; Gap Junctions; Myocardium; Nitroprusside; Permeability; Protein Kinase C; Quinolones; Rats; Serotonin; Serum Albumin; Staurosporine; Tetradecanoylphorbol Acetate | 1997 |
Inhibition of PAH transport by parathyroid hormone in OK cells: involvement of protein kinase C pathway.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Biological Transport; Bucladesine; Cell Line; Cell Membrane; Colforsin; Kidney; Kinetics; Mannitol; p-Aminohippuric Acid; Protein Kinase C; Second Messenger Systems; Staurosporine; Teriparatide; Tetradecanoylphorbol Acetate | 1997 |
Effects of protein kinase modulators on the sodium pump activities of HeLa cells transfected with distinct alpha isoforms of Na,K-ATPase.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Colforsin; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; HeLa Cells; Humans; Isoenzymes; Kinetics; Ouabain; Protein Kinase C; Rats; Recombinant Proteins; Sodium-Potassium-Exchanging ATPase; Tetradecanoylphorbol Acetate; Transfection | 1997 |
Sodium, potassium, two chloride cotransport in corneal endothelium: characterization and possible role in volume regulation and fluid transport.
Topics: 1-Methyl-3-isobutylxanthine; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Animals; Biological Transport; Bumetanide; Carrier Proteins; Cattle; Cell Size; Cells, Cultured; Chlorides; Colforsin; Dose-Response Relationship, Drug; Endothelium, Corneal; Enzyme Inhibitors; Membrane Proteins; Ouabain; Potassium; Sodium; Sodium-Potassium-Chloride Symporters; Tetradecanoylphorbol Acetate | 1998 |
Potentiation of receptor-mediated cAMP production: role in the cross-talk between vasopressin V1a and V2 receptor transduction pathways.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Animals; Arginine Vasopressin; Calcium; CHO Cells; Cholera Toxin; Cricetinae; Cyclic AMP; Deamino Arginine Vasopressin; Diglycerides; Phosphoric Diester Hydrolases; Protein Kinase C; Receptors, Vasopressin; Signal Transduction; Tetradecanoylphorbol Acetate | 1998 |
Ceramide selectively inhibits calcium-mediated potentiation of beta-adrenergic-stimulated cyclic nucleotide accumulation in rat pinealocytes.
Topics: 1-Methyl-3-isobutylxanthine; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenergic beta-Antagonists; Analgesics, Opioid; Animals; Calcium; Ceramides; Cyclic AMP; Cyclic GMP; Drug Synergism; Genistein; Isoproterenol; Male; Meperidine; Phenylephrine; Pineal Gland; Potassium; Potassium Chloride; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate | 1998 |
P2X receptors in cochlear Deiters' cells.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Calcium; Cochlea; Colforsin; Dose-Response Relationship, Drug; Enzyme Activation; Guinea Pigs; Patch-Clamp Techniques; Protein Kinases; Purinergic P2 Receptor Agonists; Receptors, Purinergic P2; Receptors, Purinergic P2X2; Tetradecanoylphorbol Acetate; Thionucleotides; Uridine Triphosphate; Vasodilator Agents; Vestibular Nucleus, Lateral | 1998 |
Modulation of secretin release by neuropeptides in secretin-producing cells.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Bombesin; Cell Line; Cell Survival; Cells, Cultured; Cyclic AMP; Diltiazem; Egtazic Acid; Galanin; Gastrin-Releasing Peptide; Inositol 1,4,5-Trisphosphate; Intestinal Mucosa; Intestine, Small; Male; Neuropeptides; Neurotransmitter Agents; Pituitary Adenylate Cyclase-Activating Polypeptide; Rats; Rats, Sprague-Dawley; Secretin; Tetradecanoylphorbol Acetate; Thionucleotides | 1998 |
Regulation of tyrosine hydroxylase gene expression during transdifferentiation of striatal neurons: changes in transcription factors binding the AP-1 site.
Topics: 1-Methyl-3-isobutylxanthine; Activating Transcription Factor 2; Animals; Base Sequence; Calcium-Calmodulin-Dependent Protein Kinases; Carcinogens; Cell Differentiation; Chamomile; Colforsin; Corpus Striatum; Cyclic AMP Response Element Modulator; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; DNA-Binding Proteins; Dopamine; Enzyme Inhibitors; Female; Fibroblast Growth Factor 1; Flavonoids; Gene Expression Regulation, Developmental; Gene Expression Regulation, Enzymologic; Molecular Sequence Data; Neurons; Oils, Volatile; Phosphodiesterase Inhibitors; Plants, Medicinal; Pregnancy; Protein Binding; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Rats; Rats, Sprague-Dawley; Repressor Proteins; Signal Transduction; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transcription Factors; Tyrosine 3-Monooxygenase | 1998 |
Gastric acid secretion is augmented by the replacement of extracellular Na+ with K+ or other ions.
Topics: 1-Methyl-3-isobutylxanthine; Aminopyrine; Animals; Atropine; Bucladesine; Calcium; Carbachol; Carcinogens; Cations; Cimetidine; Cyclic AMP; Dose-Response Relationship, Drug; Electric Stimulation; Enzyme Inhibitors; Gastric Acid; Gastric Mucosa; Histamine H2 Antagonists; In Vitro Techniques; Male; Mice; Muscarinic Agonists; Muscarinic Antagonists; Omeprazole; Potassium; Rabbits; Rotenone; Sodium; Stomach; Tetradecanoylphorbol Acetate; Uncoupling Agents; Vagus Nerve | 1998 |
Regulation of natriuretic peptide (urodilatin) release in a human kidney cell line.
Topics: 1-Methyl-3-isobutylxanthine; Atrial Natriuretic Factor; Calcimycin; Cell Line; Colforsin; Culture Media; Cyclic AMP; Cyclic GMP; Guanylate Cyclase; Humans; Intracellular Fluid; Kidney; Osmolar Concentration; Peptide Fragments; Radioimmunoassay; Tetradecanoylphorbol Acetate | 1999 |
Tyrosine kinases play a permissive role in glucose-induced insulin secretion from adult rat islets.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Calcium; Calcium Channels; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Genistein; Glucose; Insulin; Insulin Secretion; Ion Transport; Islets of Langerhans; Isoflavones; Leupeptins; Phenylmethylsulfonyl Fluoride; Phosphorylation; Protein Kinase C; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Rats; Rats, Sprague-Dawley; Second Messenger Systems; Tetradecanoylphorbol Acetate; Tyrphostins; Vanadates | 1999 |
Sodium, PMA and calcium play an important role on intracellular pH modulation in rat mast cells.
Topics: 1-Methyl-3-isobutylxanthine; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Animals; Calcium; Cyclic AMP; Enzyme Inhibitors; Hydrogen-Ion Concentration; Ion Transport; Mast Cells; Ouabain; Rats; Rats, Sprague-Dawley; Signal Transduction; Sodium; Sodium-Hydrogen Exchangers; Spectrometry, Fluorescence; Tetradecanoylphorbol Acetate; Thapsigargin | 1998 |
[Intracellular regulation of neuronal nicotinic cholinergic receptors].
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Animals; Calcium; Colforsin; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP-Dependent Protein Kinases; Enzyme Activation; In Vitro Techniques; Membrane Potentials; Neurons; Patch-Clamp Techniques; Phosphodiesterase Inhibitors; Protein Kinase C; Rats; Receptors, Nicotinic; Superior Cervical Ganglion; Tetradecanoylphorbol Acetate; Thapsigargin | 1998 |
AMP deaminase in piglet cardiac myocytes: effect on nucleotide metabolism during ischemia.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; AMP Deaminase; Animals; Animals, Newborn; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Carcinogens; Carotenoids; Cells, Cultured; Cyclic AMP; Energy Metabolism; Enzyme Activation; Heart Ventricles; Ischemic Preconditioning; Muscle Fibers, Skeletal; Myocardial Ischemia; Myocardium; Oxygenases; Phosphodiesterase Inhibitors; Swine; Tetradecanoylphorbol Acetate; Uncoupling Agents | 1999 |
Divergent mechanisms regulate proliferation/survival and steroidogenesis of theca-interstitial cells.
Topics: 1-Methyl-3-isobutylxanthine; 3-Hydroxysteroid Dehydrogenases; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Cell Division; Cell Survival; Cells, Cultured; Colforsin; Cyclic AMP; DNA; Female; Hormone Antagonists; Insulin-Like Growth Factor I; Luteinizing Hormone; Mifepristone; Progesterone; Protein Kinase C; Rats; Rats, Sprague-Dawley; Testosterone; Tetradecanoylphorbol Acetate; Theca Cells | 1999 |
Role of proteoglycans on testosterone synthesis by purified Leydig cells from immature and mature rats.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Bucladesine; Cells, Cultured; Chorionic Gonadotropin; Cyclic AMP; Glucosamine; Glycosaminoglycans; Glycosides; Hydroxycholesterols; Leydig Cells; Luteinizing Hormone; Male; Nitrophenylgalactosides; Proteoglycans; Rats; Rats, Sprague-Dawley; Sexual Maturation; Signal Transduction; Sulfates; Testis; Testosterone; Tetradecanoylphorbol Acetate | 1999 |
Vimentin-dependent utilization of LDL-cholesterol in human adrenal tumor cells is not associated with the level of expression of apoE, sterol carrier protein-2, or caveolin.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Adrenal Gland Neoplasms; Animals; Apolipoproteins E; Carrier Proteins; Caveolin 1; Caveolin 2; Caveolins; Cell Compartmentation; Cholesterol Esters; Cholesterol, LDL; Esterification; Fluorescent Antibody Technique; Gene Expression Regulation, Neoplastic; Humans; Intermediate Filaments; Membrane Proteins; Mice; Plant Proteins; Protein Kinases; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Vimentin | 1999 |
A novel calcium signaling pathway targets the c-fos intragenic transcriptional pausing site.
Topics: 1-Methyl-3-isobutylxanthine; 5' Untranslated Regions; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Calcimycin; Calcineurin; Calcium; Calmodulin; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Gene Expression Regulation; Genes, fos; Genes, Reporter; Humans; Introns; L Cells; Metallothionein; Mice; Mitogen-Activated Protein Kinases; Phosphorylation; Promoter Regions, Genetic; Recombinant Fusion Proteins; Serine; Signal Transduction; Sulfonamides; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1999 |
Calbindin-D(28k) controls [Ca(2+)](i) and insulin release. Evidence obtained from calbindin-d(28k) knockout mice and beta cell lines.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Calbindins; Calcium; Immunohistochemistry; Insulin; Insulin Secretion; Islets of Langerhans; Mice; Mice, Knockout; Mutation; Potassium Chloride; Rats; Recombinant Fusion Proteins; S100 Calcium Binding Protein G; Tetradecanoylphorbol Acetate; Tissue Distribution; Tumor Cells, Cultured | 1999 |
Mechanisms involved in desensitization of particulate guanylyl cyclase in human airway smooth muscle: the role of protein kinase C.
Topics: 1-Methyl-3-isobutylxanthine; Atrial Natriuretic Factor; Cells, Cultured; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Activation; Guanylate Cyclase; Humans; Indoles; Maleimides; Muscle, Smooth; Phorbols; Phosphodiesterase Inhibitors; Protein Kinase C; Respiratory System; Solubility; Tetradecanoylphorbol Acetate; Time Factors | 1999 |
Ca(2+) and extracellular acidification rate responses to parathyroid hormone fragments in rat ROS 17/2 and human SaOS-2 cells.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Alkaloids; Animals; Benzophenanthridines; Calcium; Cell Line; Colforsin; Cyclic AMP-Dependent Protein Kinases; Fura-2; Humans; Hydrogen-Ion Concentration; Kinetics; Parathyroid Hormone; Peptide Fragments; Phenanthridines; Protein Kinase C; Rats; Signal Transduction; Spectrometry, Fluorescence; Tetradecanoylphorbol Acetate | 1999 |
The role of phosphodiesterase in mediating the effect of protein kinase C on cyclic AMP accumulation upon kappa-opioid receptor stimulation in the rat heart.
Topics: 1-Methyl-3-isobutylxanthine; 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Alkaloids; Animals; Benzophenanthridines; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Male; Myocardium; Phenanthridines; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Tetradecanoylphorbol Acetate | 2000 |
Regulation of mouse delta-opioid receptor gene transcription: involvement of the transcription factors AP-1 and AP-2.
Topics: 1-Methyl-3-isobutylxanthine; Aged; Animals; Carcinogens; Colforsin; Cyclic AMP-Dependent Protein Kinases; DNA-Binding Proteins; Gene Expression Regulation, Enzymologic; Genetic Complementation Test; Glioma; Humans; Mice; Phosphodiesterase Inhibitors; Promoter Regions, Genetic; Protein Kinase C; Receptor Cross-Talk; Receptors, Opioid, delta; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transcription Factor AP-2; Transcription Factors; Transcription, Genetic; Tumor Cells, Cultured | 2000 |
Direct measurement of hormone-induced acidification in intact bone.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Animals; Animals, Newborn; Bone and Bones; Bone Neoplasms; Bucladesine; Calcium Signaling; Carbonic Anhydrases; Colforsin; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Extracellular Space; Humans; Hydrogen-Ion Concentration; Mice; Organ Culture Techniques; Organ Specificity; Osteoblasts; Osteosarcoma; Parathyroid Hormone; Protein Kinase C; Second Messenger Systems; Skull; Tetradecanoylphorbol Acetate; Thapsigargin; Tumor Cells, Cultured | 2000 |
Conversion and storage of somatostatin are established before response to secretagogue stimuli in P19 neurons.
Topics: 1-Methyl-3-isobutylxanthine; Aging; Animals; Carcinogens; Cell Differentiation; Central Nervous System; Chromogranin A; Chromogranins; Gene Expression Regulation, Developmental; Ionophores; Mice; Neoplastic Stem Cells; Neurons; Peptide Hydrolases; Phosphodiesterase Inhibitors; Potassium Chloride; Protein Precursors; Proteins; Secretory Vesicles; Somatostatin; Tetradecanoylphorbol Acetate | 2000 |
Coordinate regulation of neuroendocrine convertase PC2 and peptide 7B2 in P19 neurons.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Bucladesine; Carcinoma, Embryonal; Cell Differentiation; Dexamethasone; Gene Expression Regulation; Mice; Nerve Tissue Proteins; Neuroendocrine Secretory Protein 7B2; Neurons; Pituitary Hormones; Proprotein Convertase 2; Subtilisins; Tetradecanoylphorbol Acetate; Triiodothyronine; Tumor Cells, Cultured | 2000 |
Regulation of the diabetes-associated autoantigen IA-2 in INS-1 pancreatic beta-cells.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Autoantigens; Colforsin; Cyclic AMP; Gene Expression Regulation; Glucagon; Glucose; Insulinoma; Islets of Langerhans; Kinetics; Membrane Proteins; Pancreatic Neoplasms; Protein Kinase C; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Protein Tyrosine Phosphatases; Rats; Receptor-Like Protein Tyrosine Phosphatases, Class 8; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Somatostatin; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 2000 |
Cellular mechanism of sodium oleate-stimulated secretion of cholecystokinin and secretin.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Biological Transport; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Calmodulin; Cell Fractionation; Cells, Cultured; Chelating Agents; Cholecystokinin; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Duodenum; Egtazic Acid; Enzyme Inhibitors; Intestinal Mucosa; Isoquinolines; Oleic Acid; Phosphodiesterase Inhibitors; Protein Kinase C; Rats; Secretin; Sulfonamides; Tetradecanoylphorbol Acetate | 2000 |
Cyclic nucleotide regulation of Na+/glucose cotransporter (SGLT1) mRNA stability. Interaction of a nucleocytoplasmic protein with a regulatory domain in the 3'-untranslated region critical for stabilization.
Topics: 1-Methyl-3-isobutylxanthine; 3' Untranslated Regions; Animals; Binding Sites; Cell Line; Cell Nucleus; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cytoplasm; Membrane Glycoproteins; Monosaccharide Transport Proteins; Protein Structure, Secondary; RNA; RNA, Messenger; Sodium-Glucose Transporter 1; Swine; Tetradecanoylphorbol Acetate | 2000 |
Effect of HCO(3)(-) on TPA- and IBMX-induced anion conductances in Necturus gallbladder epithelial cells.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Anions; Bicarbonates; Electric Conductivity; Epithelial Cells; Gallbladder; In Vitro Techniques; Necturus maculosus; Tetradecanoylphorbol Acetate | 2000 |
The induction of the human hepatic CYP2E1 gene by interleukin 4 is transcriptional and regulated by protein kinase C.
Topics: 1-Methyl-3-isobutylxanthine; Bucladesine; Carcinoma, Hepatocellular; Cytochrome P-450 CYP2E1; Gene Expression Regulation, Enzymologic; Hepatocytes; Humans; Interleukin-4; Kinetics; Liver; Liver Neoplasms; Protein Biosynthesis; Protein Kinase C; RNA, Messenger; STAT6 Transcription Factor; Tetradecanoylphorbol Acetate; Trans-Activators; Transcription, Genetic; Tumor Cells, Cultured | 2000 |
Parathyroid hormone-related protein down-regulates bone sialoprotein gene expression in cementoblasts: role of the protein kinase A pathway.
Topics: 1-Methyl-3-isobutylxanthine; Cell Line; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cycloheximide; Dactinomycin; Dental Cementum; Dose-Response Relationship, Drug; Enzyme Inhibitors; Gene Expression Regulation; Integrin-Binding Sialoprotein; Kinetics; Parathyroid Hormone-Related Protein; Phorbol 12,13-Dibutyrate; Proteins; RNA, Messenger; Second Messenger Systems; Sialoglycoproteins; Tetradecanoylphorbol Acetate; Thionucleotides | 2000 |
Functional characterisation of human TASK-3, an acid-sensitive two-pore domain potassium channel.
Topics: 1-Methyl-3-isobutylxanthine; Acids; Animals; Barium Compounds; Bupivacaine; Cell Line; Cesium; Chlorides; Colforsin; Dose-Response Relationship, Drug; Female; Gene Expression; Glyburide; Halothane; Humans; Kinetics; Membrane Potentials; Oocytes; Potassium; Potassium Channels; Potassium Channels, Tandem Pore Domain; Pregnanediones; Tetradecanoylphorbol Acetate; Tetraethylammonium; Time Factors; Xenopus | 2001 |
Biphasic response to human galanin of extracellular acidification in human Bowes melanoma cells.
Topics: 1-Methyl-3-isobutylxanthine; Acids; Amiloride; Cell Line; Colforsin; Dose-Response Relationship, Drug; Extracellular Space; Galanin; Gene Expression; Humans; Hydrogen-Ion Concentration; Melanoma; Peptide Fragments; Pertussis Toxin; Receptors, Galanin; Receptors, Neuropeptide; RNA, Messenger; Tetradecanoylphorbol Acetate; Time Factors; Tumor Cells, Cultured; Virulence Factors, Bordetella | 2001 |
Parathyroid hormone receptor internalization is independent of protein kinase A and phospholipase C activation.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Binding Sites; Cell Line; Cell Membrane; Coated Pits, Cell-Membrane; Colforsin; COS Cells; Cyclic AMP-Dependent Protein Kinases; Cytoplasm; Enzyme Activation; Gene Expression; Green Fluorescent Proteins; Kinetics; Luminescent Proteins; Mutagenesis; Parathyroid Hormone; Phosphorylation; Protein Kinase C; Rats; Receptors, Parathyroid Hormone; Recombinant Fusion Proteins; Signal Transduction; Tetradecanoylphorbol Acetate; Transfection; Type C Phospholipases | 2001 |
Inhibition of the glutamate transporter EAAC1 expressed in Xenopus oocytes by phorbol esters.
Topics: 1-Methyl-3-isobutylxanthine; Amino Acid Transport System X-AG; Animals; Carcinogens; Carrier Proteins; Cell Membrane; Colforsin; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Enzyme Inhibitors; Excitatory Amino Acid Transporter 3; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Humans; Indoles; Maleimides; Membrane Potentials; Oocytes; Phorbols; Protein Kinase C; RNA, Complementary; Symporters; Tetradecanoylphorbol Acetate; Tritium; Tumor Cells, Cultured; Xenopus laevis | 2001 |
Alternative splicing of CRH-R1 receptors in human and mouse skin: identification of new variants and their differential expression.
Topics: 1-Methyl-3-isobutylxanthine; Alternative Splicing; Animals; Bucladesine; Cell Line; Colforsin; Gene Expression Regulation; Humans; Protein Isoforms; Receptors, Corticotropin-Releasing Hormone; RNA, Messenger; Skin; Tetradecanoylphorbol Acetate; Tissue Distribution; Tumor Cells, Cultured; Ultraviolet Rays | 2001 |
Identification of signal transduction pathways and promoter sequences that mediate parathyroid hormone 1-38 inhibition of osteoprotegerin gene expression.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Bucladesine; Calcimycin; Colforsin; Gene Expression; Glycoproteins; Osteoblasts; Osteoprotegerin; Parathyroid Hormone; Parathyroid Hormone-Related Protein; Peptide Fragments; Promoter Regions, Genetic; Proteins; Rats; Receptors, Cytoplasmic and Nuclear; Receptors, Tumor Necrosis Factor; Signal Transduction; Tetradecanoylphorbol Acetate; Thapsigargin | 2001 |
Cyclic AMP-dependent kinase regulates Raf-1 kinase mainly by phosphorylation of serine 259.
Topics: 1-Methyl-3-isobutylxanthine; 3T3 Cells; Animals; Colforsin; COS Cells; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Genes, Reporter; Mice; Mitogen-Activated Protein Kinases; Peptide Mapping; Phosphodiesterase Inhibitors; Phosphorylation; Proto-Oncogene Proteins c-raf; Serine; Signal Transduction; Tetradecanoylphorbol Acetate | 2002 |
Nitrolinoleate inhibits superoxide generation, degranulation, and integrin expression by human neutrophils: novel antiinflammatory properties of nitric oxide-derived reactive species in vascular cells.
Topics: 1-Methyl-3-isobutylxanthine; Anti-Inflammatory Agents; Calcium; Cell Degranulation; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Humans; Integrins; Linoleic Acid; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; Neutrophils; Nitro Compounds; Phosphodiesterase Inhibitors; Superoxides; Tetradecanoylphorbol Acetate | 2002 |
Inhibitory effects of cAMP and protein kinase C on meiotic maturation and MAP kinase phosphorylation in porcine oocytes.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Cell Cycle; Cyclic AMP; Diglycerides; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Female; Meiosis; Mitogen-Activated Protein Kinases; Oocytes; Phosphorylation; Protein Kinase C; Swine; Tetradecanoylphorbol Acetate | 2002 |
Pharmacological properties of glycine transport in the frog retina.
Topics: 1-Methyl-3-isobutylxanthine; Amoxapine; Animals; Biological Transport; Colforsin; Glycine; Ranidae; Retina; Sarcosine; Tetradecanoylphorbol Acetate | 2004 |
Phosphatidylinositol 3-kinase/Akt-dependent and -independent protection against apoptosis in normal human melanocytes.
Topics: 1-Methyl-3-isobutylxanthine; Adenoviridae; Apoptosis; Carcinogens; Fibroblast Growth Factor 2; Humans; Hypoglycemic Agents; Insulin; Melanocytes; Mutation; Phosphatidylinositol 3-Kinases; Phosphodiesterase Inhibitors; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Signal Transduction; Tetradecanoylphorbol Acetate | 2004 |
Differentiation of human bone marrow stem cells into cells with a neural phenotype: diverse effects of two specific treatments.
Topics: 1-Methyl-3-isobutylxanthine; Adolescent; Adult; Antigens, CD; Blotting, Western; Bone Marrow Cells; Cell Differentiation; Cell Size; Cells, Cultured; Child; Colforsin; Fibroblast Growth Factor 1; Flow Cytometry; Gene Expression Regulation; Glial Fibrillary Acidic Protein; Humans; Immunohistochemistry; Intermediate Filament Proteins; Mercaptoethanol; Microscopy, Electron, Scanning; Nerve Tissue Proteins; Nestin; Neurofilament Proteins; Neurons; Phenotype; Phosphodiesterase Inhibitors; Phosphopyruvate Hydratase; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stem Cells; Tetradecanoylphorbol Acetate; Time Factors; Tretinoin | 2006 |
Human astrocytes can be induced to differentiate into cells with neuronal phenotype.
Topics: 1-Methyl-3-isobutylxanthine; Astrocytes; Basic Helix-Loop-Helix Transcription Factors; Blotting, Western; Brain; Cell Differentiation; Cell Proliferation; Cells, Cultured; Colforsin; Fetus; Fibroblast Growth Factor 1; Gene Expression; Glial Fibrillary Acidic Protein; Homeodomain Proteins; Humans; Intermediate Filament Proteins; Membrane Potentials; Nerve Tissue Proteins; Nestin; Neurofilament Proteins; Neurons; Phosphopyruvate Hydratase; RNA, Messenger; Synaptophysin; Tetradecanoylphorbol Acetate; Transcription Factor HES-1; Tubulin | 2006 |
Control of cyclic AMP concentration in bovine endometrial stromal cells by arachidonic acid.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclase Inhibitors; Animals; Arachidonic Acid; Cattle; Cells, Cultured; Colforsin; Cyclic AMP; Cyclooxygenase 2; Depression, Chemical; Dinoprostone; Endometrium; Female; Indoles; Maleimides; Paracrine Communication; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Protein Kinase C; Stromal Cells; Tetradecanoylphorbol Acetate | 2007 |
Regulation of C/EBPbeta mRNA expression and C/EBPbeta promoter activity by protein kinases A and C in a myelomonocytic cell line (HD11).
Topics: 1-Methyl-3-isobutylxanthine; Animals; Base Sequence; CCAAT-Enhancer-Binding Protein-beta; Cell Line; Chickens; Colforsin; Cyclic AMP-Dependent Protein Kinases; Gene Expression Regulation; Humans; Mice; Molecular Sequence Data; Monocytes; Phosphodiesterase Inhibitors; Promoter Regions, Genetic; Protein Kinase C; RNA Stability; RNA, Messenger; Sequence Alignment; Signal Transduction; Tetradecanoylphorbol Acetate | 2007 |
Vasoactive intestinal peptide increases cystic fibrosis transmembrane conductance regulator levels in the apical membrane of Calu-3 cells through a protein kinase C-dependent mechanism.
Topics: 1-Methyl-3-isobutylxanthine; Benzophenanthridines; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; Cystic Fibrosis Transmembrane Conductance Regulator; Endocytosis; Humans; Indoles; Maleimides; Protein Kinase C; Tetradecanoylphorbol Acetate; Vasoactive Intestinal Peptide | 2008 |
The identification of inhibitors of Schistosoma mansoni miracidial transformation by incorporating a medium-throughput small-molecule screen.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Anthelmintics; Benzophenanthridines; Calcimycin; Calcium Channel Blockers; Citalopram; Clomipramine; Colforsin; Cyclic AMP; Dimethyl Sulfoxide; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Immunohistochemistry; Mice; Schistosoma mansoni; Tetradecanoylphorbol Acetate; Triflupromazine | 2010 |
Tuning the endothelial response: differential release of exocytic cargos from Weibel-Palade bodies.
Topics: 1-Methyl-3-isobutylxanthine; Actomyosin; Cytochalasins; Endothelial Cells; Epinephrine; Exocytosis; Hemostasis; Heterocyclic Compounds, 4 or More Rings; Histamine; Human Umbilical Vein Endothelial Cells; Humans; Inflammation; Leukocyte Rolling; P-Selectin; Protein Conformation; RNA Interference; RNA, Small Interfering; Tetradecanoylphorbol Acetate; von Willebrand Factor; Weibel-Palade Bodies | 2018 |