1-methyl-3-isobutylxanthine and tadalafil

1-methyl-3-isobutylxanthine has been researched along with tadalafil in 2 studies

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	2 (100.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Hughes, RA; Manallack, DT; Thompson, PE	1
Corbin, JD; Francis, SH; Zoraghi, R	1

Reviews

1 review(s) available for 1-methyl-3-isobutylxanthine and tadalafil

Article	Year
The next generation of phosphodiesterase inhibitors: structural clues to ligand and substrate selectivity of phosphodiesterases. Journal of medicinal chemistry, 2005, May-19, Volume: 48, Issue:10 Topics: Animals; Binding Sites; Crystallography, X-Ray; Cyclic AMP; Cyclic GMP; Drug Design; Humans; Models, Molecular; Molecular Structure; Phosphodiesterase Inhibitors; Quantitative Structure-Activity Relationship; Xanthines	2005

Article

Year

The next generation of phosphodiesterase inhibitors: structural clues to ligand and substrate selectivity of phosphodiesterases.

Journal of medicinal chemistry, 2005, May-19, Volume: 48, Issue:10

Topics: Animals; Binding Sites; Crystallography, X-Ray; Cyclic AMP; Cyclic GMP; Drug Design; Humans; Models, Molecular; Molecular Structure; Phosphodiesterase Inhibitors; Quantitative Structure-Activity Relationship; Xanthines

2005

Other Studies

1 other study(ies) available for 1-methyl-3-isobutylxanthine and tadalafil

Article	Year
Critical amino acids in phosphodiesterase-5 catalytic site that provide for high-affinity interaction with cyclic guanosine monophosphate and inhibitors. Biochemistry, 2007, Nov-27, Volume: 46, Issue:47 Topics: 1-Methyl-3-isobutylxanthine; Amino Acid Sequence; Animals; Binding Sites; Carbolines; Catalytic Domain; Crystallography, X-Ray; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 5; Histidine; Humans; Hydrophobic and Hydrophilic Interactions; Imidazoles; Kinetics; Molecular Sequence Data; Mutation; Phosphodiesterase 5 Inhibitors; Phosphodiesterase Inhibitors; Piperazines; Purines; Sequence Alignment; Sildenafil Citrate; Sulfones; Tadalafil; Thermodynamics; Triazines; Tyrosine; Vardenafil Dihydrochloride	2007

Article

Year

Critical amino acids in phosphodiesterase-5 catalytic site that provide for high-affinity interaction with cyclic guanosine monophosphate and inhibitors.

Biochemistry, 2007, Nov-27, Volume: 46, Issue:47

Topics: 1-Methyl-3-isobutylxanthine; Amino Acid Sequence; Animals; Binding Sites; Carbolines; Catalytic Domain; Crystallography, X-Ray; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 5; Histidine; Humans; Hydrophobic and Hydrophilic Interactions; Imidazoles; Kinetics; Molecular Sequence Data; Mutation; Phosphodiesterase 5 Inhibitors; Phosphodiesterase Inhibitors; Piperazines; Purines; Sequence Alignment; Sildenafil Citrate; Sulfones; Tadalafil; Thermodynamics; Triazines; Tyrosine; Vardenafil Dihydrochloride

2007