1-methyl-3-isobutylxanthine has been researched along with pimobendan in 8 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (25.00) | 18.7374 |
| 1990's | 6 (75.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fujimoto, S; Matsuda, T | 1 |
| Mende, U; Meyer, W; Neumann, J; Nose, M; Schmitz, W; Scholz, H; Starbatty, J; Stein, B; von der Leyen, H; Wenzlaff, H | 1 |
| Meyer, W; Scholz, H | 1 |
| Berger, C; Meyer, W; Scholz, H; Starbatty, J | 1 |
| Erdmann, E | 1 |
| Hagiwara, N; Hosoda, S; Kajimoto, K; Kasanuki, H | 1 |
| Conti, M; Hanssen, RG; Hirsch, B; Hsueh, AJ; Kloosterboer, HJ; Tsafriri, A; Van de Kant, M; Wiersma, A | 1 |
| Arita, M; Dohi, K; Kiyosue, T; Matsui, K; Wang, JC | 1 |
8 other study(ies) available for 1-methyl-3-isobutylxanthine and pimobendan
| Article | Year |
|---|---|
Effects of pimobendan, a cardiotonic and vasodilating agent with phosphodiesterase inhibiting properties, on isolated arteries and veins of rats.
Topics: 1-Methyl-3-isobutylxanthine; Aminophylline; Animals; Arteries; Cardiotonic Agents; Colforsin; Drug Interactions; In Vitro Techniques; Isoproterenol; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Phosphodiesterase Inhibitors; Pyridazines; Rats; Rats, Inbred Strains; Vasodilator Agents; Veins | 1990 |
Mechanism underlying the reduced positive inotropic effects of the phosphodiesterase III inhibitors pimobendan, adibendan and saterinone in failing as compared to nonfailing human cardiac muscle preparations.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Adult; Aged; Benzimidazoles; Calcium; Cardiac Output, Low; Cardiotonic Agents; Cyclic AMP; Female; Heart; Humans; Imidazoles; In Vitro Techniques; Isoenzymes; Male; Middle Aged; Myocardial Contraction; Myocardium; Ouabain; Oxindoles; Phosphodiesterase Inhibitors; Piperazines; Pyridazines; Pyridones | 1991 |
Phosphodiesterase-inhibiting properties of newer inotropic agents.
Topics: 1-Methyl-3-isobutylxanthine; Aminopyridines; Amrinone; Animals; Calcium; Cardiotonic Agents; Cyclic AMP; Dose-Response Relationship, Drug; Guinea Pigs; Imidazoles; Milrinone; Myocardial Contraction; Phosphodiesterase Inhibitors; Pyridazines; Pyridones; Theophylline | 1986 |
Effects of the benzimidazole derivatives pimobendan and 2-(4-hydroxy-phenyl)-5-(5-methyl-3-oxo-4,5-dihydro-2H-6- pyridazinyl) benzimidazole . HCl on phosphodiesterase activity and force of contraction in guinea-pig hearts.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adenylyl Cyclases; Animals; Carbachol; Cardiotonic Agents; Female; Guinea Pigs; Heart Atria; Histamine; In Vitro Techniques; Isoproterenol; Male; Myocardial Contraction; Myocardium; Ouabain; Papillary Muscles; Phenylisopropyladenosine; Phosphodiesterase Inhibitors; Pyridazines | 1985 |
The effect of positive inotropes on the failing human myocardium.
Topics: 1-Methyl-3-isobutylxanthine; Adrenergic beta-Agonists; Calcium; Cardiotonic Agents; Dobutamine; Heart Failure; Humans; In Vitro Techniques; Isoproterenol; Milrinone; Myocardial Contraction; Papillary Muscles; Phosphodiesterase Inhibitors; Pyridazines; Pyridones | 1997 |
Contribution of phosphodiesterase isozymes to the regulation of the L-type calcium current in human cardiac myocytes.
Topics: 1-Methyl-3-isobutylxanthine; Adolescent; Adult; Animals; Calcium Channels; Calcium Channels, L-Type; Child; Child, Preschool; Cyclic AMP; Dose-Response Relationship, Drug; Heart; Humans; Infant; Isoenzymes; Middle Aged; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Pyridazines; Rabbits | 1997 |
Phosphodiesterase 3 inhibitors suppress oocyte maturation and consequent pregnancy without affecting ovulation and cyclicity in rodents.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Contraceptive Agents, Female; Cyclic AMP; Cyclic Nucleotide Phosphodiesterases, Type 3; Estrus; Female; Fertilization; Heart Rate; Hypoxanthine; Isoenzymes; Meiosis; Menotropins; Mice; Mice, Inbred C57BL; Milrinone; Oogenesis; Ovarian Follicle; Ovulation; Ovulation Induction; Phosphodiesterase Inhibitors; Pregnancy; Purinones; Pyridazines; Pyridones; Pyrrolidinones; Quinolones; Rats; Rats, Sprague-Dawley; Rolipram; Second Messenger Systems; Substrate Specificity; Thiophenes | 1998 |
Effects of pimobendan on the L-type Ca2+ current and developed tension in guinea-pig ventricular myocytes and papillary muscle: comparison with IBMX, milrinone, and cilostazol.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Calcium Channels; Cardiotonic Agents; Cilostazol; Guinea Pigs; Heart Ventricles; In Vitro Techniques; Milrinone; Myocardial Contraction; Papillary Muscles; Patch-Clamp Techniques; Phosphodiesterase Inhibitors; Pyridazines; Tetrazoles | 1999 |