1-methyl-3-isobutylxanthine and n-formylmethionine leucyl-phenylalanine

1-methyl-3-isobutylxanthine has been researched along with n-formylmethionine leucyl-phenylalanine in 37 studies

Research

Studies (37)

TimeframeStudies, this research(%)All Research%
pre-199010 (27.03)18.7374
1990's22 (59.46)18.2507
2000's5 (13.51)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Richter, J1
Glovsky, MM; Kebo, DK; Kunkel, S; Nagata, S1
Burde, R; Buschauer, A; Seifert, R1
Devall, LJ; Klinkefus, BA; Kobylarz-Singer, D; Kuipers, PJ; Weishaar, RE; Wright, CD1
Ney, P; Schröder, H; Schrör, K; Woditsch, I1
Harvath, L; Robbins, JD; Russell, AA; Seamon, KB1
Barrett, TA; Chang, EB; Musch, MW1
Agwu, DE; McCall, CE; McPhail, LC1
Gunther, GR; Herring, MB1
Downey, GP; Elson, EL; Erzurum, SC; Schwab, B; Worthen, GS; Young, SK1
Abraham, RT; Abu-Ghazaleh, RI; Gleich, GJ; Kita, H1
Ervens, J; Seifert, R; Wenzel-Seifert, K1
Goldberg, BJ; Lad, PM; Olson, CV; Smiley, PA1
Ishitoya, J; Takenawa, T1
Schmeichel, CJ; Thomas, LL1
Post, TJ; Schulman, ES; Vigderman, RJ1
Godfrey, RW; Hoffstein, ST; Jensen, BD; Manzi, RM1
Fox, K; McPhail, LC; Snyderman, R; Verghese, MW1
Carchman, RA; Debski, BF; Ranney, RR1
Blandina, P; Brunelleschi, S; Cambi, S; Fantozzi, R; Mannaioni, PF; Masini, E1
Columbo, M; Condorelli, M; Marone, G; Soppelsa, L1
Okajima, F; Ui, M1
Andersson, T; Löfgren, R; Ng-Sikorski, J; Sjölander, A1
Botana, LM; MacGlashan, DW1
Buzzi, M; Cavallaro, R; Ferretti, ME; Paradisi, MP; Pareschi, MC; Reali, E; Spisani, S; Torrini, I; Traniello, S; Zecchini, GP1
Ahmed, MU; Hazeki, K; Hazeki, O; Katada, T; Ui, M1
Blum, G; Caramelo, C; Casado, S; Gallego, MJ; López Farré, A; Montón, M; Riesco, A1
Tool, AT; Verhoeven, AJ1
Gladis-Villanueva, M; Schrör, K1
Newsholme, P; O'Dowd, Y1
Andersson, T; Molony, L; Ng-Sikorski, J; Ydrenius, L1
de Koster, BM; Elferink, JG; Huizinga, TW1
Conigrave, AD; Luttrell, BM; Morris, MB; Rakyan, V; van der Weyden, L1
Byrnes, HD; Fine, JS; Hipkin, RW; Zavodny, PJ1
Dahms, TE; Nishino, M; Tanaka, H1
Bloodsworth, A; Clark, SR; Coles, B; Cross, AR; Freeman, BA; Lewis, MJ; O'Donnell, VB1
Djanani, AM; Feistritzer, C; Kaneider, NC; Lindner, J; Mosheimer, BA; Sturn, DH; Wiedermann, CJ1

Other Studies

37 other study(ies) available for 1-methyl-3-isobutylxanthine and n-formylmethionine leucyl-phenylalanine

ArticleYear
Effect of adenosine analogues and cAMP-raising agents on TNF-, GM-CSF-, and chemotactic peptide-induced degranulation in single adherent neutrophils.
    Journal of leukocyte biology, 1992, Volume: 51, Issue:3

    Topics: 1-Methyl-3-isobutylxanthine; 2-Chloroadenosine; Adenosine; Blood Proteins; Bucladesine; Cell Adhesion; Cell Degranulation; Chemotactic Factors; Colforsin; Cyclic AMP; Cytochalasin B; Exocytosis; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha

1992
Effect of adenylate cyclase activators on C5a-induced human neutrophil aggregation, enzyme release and superoxide production.
    International archives of allergy and immunology, 1992, Volume: 97, Issue:3

    Topics: 1-Methyl-3-isobutylxanthine; Alprostadil; Cell Aggregation; Complement C5a; Cyclic AMP; Dinoprost; Dinoprostone; Dose-Response Relationship, Drug; Epinephrine; Humans; In Vitro Techniques; Isoproterenol; Muramidase; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Prostaglandins E; Radioimmunoassay; Superoxides

1992
Characterization of histamine H2-receptors in human neutrophils with a series of guanidine analogues of impromidine. Are cell type-specific H2-receptors involved in the regulation of NADPH oxidase?
    Naunyn-Schmiedeberg's archives of pharmacology, 1990, Volume: 341, Issue:5

    Topics: 1-Methyl-3-isobutylxanthine; Cardiotonic Agents; Cimetidine; Dose-Response Relationship, Drug; Famotidine; Guanidines; Humans; Imidazoles; Impromidine; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Receptors, Histamine H2; Superoxides

1990
Differential inhibition of human neutrophil functions. Role of cyclic AMP-specific, cyclic GMP-insensitive phosphodiesterase.
    Biochemical pharmacology, 1990, Aug-15, Volume: 40, Issue:4

    Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Cyclic AMP; Cyclic Nucleotide Phosphodiesterases, Type 1; Humans; Lysosomes; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxygen Consumption; Phosphodiesterase Inhibitors; Pyrrolidinones; Rolipram

1990
Cyclic GMP mediates SIN-1-induced inhibition of human polymorphonuclear leukocytes.
    European journal of pharmacology, 1990, Jul-03, Volume: 182, Issue:2

    Topics: 1-Methyl-3-isobutylxanthine; Cyanides; Cyclic AMP; Cyclic GMP; Glucuronidase; Humans; In Vitro Techniques; Macrophage Activation; Methylene Blue; Molsidomine; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Nitroglycerin; Nitroprusside; Nitrosamines; Vasodilator Agents

1990
cAMP and human neutrophil chemotaxis. Elevation of cAMP differentially affects chemotactic responsiveness.
    Journal of immunology (Baltimore, Md. : 1950), 1991, Jan-01, Volume: 146, Issue:1

    Topics: 1-Methyl-3-isobutylxanthine; Alprostadil; Biological Transport; Chemotaxis, Leukocyte; Colforsin; Cyclic AMP; Humans; In Vitro Techniques; Isoproterenol; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Time Factors

1991
Chemotactic peptide effects on intestinal electrolyte transport.
    The American journal of physiology, 1990, Volume: 259, Issue:6 Pt 1

    Topics: 1-Methyl-3-isobutylxanthine; Alprostadil; Animals; Chlorides; Colon; Cyclic AMP; Dinoprostone; Electric Conductivity; Epithelium; Ileum; In Vitro Techniques; Intestinal Mucosa; Male; Membrane Potentials; Muscle, Smooth; N-Formylmethionine Leucyl-Phenylalanine; Piroxicam; Rabbits

1990
Regulation of phospholipase D-induced hydrolysis of choline-containing phosphoglycerides by cyclic AMP in human neutrophils.
    Journal of immunology (Baltimore, Md. : 1950), 1991, Jun-01, Volume: 146, Issue:11

    Topics: 1-Methyl-3-isobutylxanthine; Cyclic AMP; Dinoprostone; Humans; Hydrolysis; In Vitro Techniques; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphatidic Acids; Phosphatidylcholines; Phospholipase D; Tetradecanoylphorbol Acetate

1991
Inhibition of neutrophil superoxide production by adenosine released from vascular endothelial cells.
    Annals of vascular surgery, 1991, Volume: 5, Issue:4

    Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adenosine Deaminase; Adenosine-5'-(N-ethylcarboxamide); Cells, Cultured; Endothelium, Vascular; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pentostatin; Superoxides; Umbilical Veins

1991
Biophysical properties and microfilament assembly in neutrophils: modulation by cyclic AMP.
    The Journal of cell biology, 1991, Volume: 114, Issue:6

    Topics: 1-Methyl-3-isobutylxanthine; Actin Cytoskeleton; Bucladesine; Cyclic AMP; Dinoprostone; Humans; Kinetics; Microscopy, Fluorescence; Models, Biological; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Protein Kinases

1991
Role of pertussis toxin-sensitive G proteins in stimulus-dependent human eosinophil degranulation.
    Journal of immunology (Baltimore, Md. : 1950), 1991, Nov-15, Volume: 147, Issue:10

    Topics: 1-Methyl-3-isobutylxanthine; Adenosine Diphosphate Ribose; Antigens, Differentiation; Calcimycin; Cell Degranulation; Cholera Toxin; Cyclic AMP; Eosinophil-Derived Neurotoxin; Eosinophils; GTP-Binding Proteins; Humans; In Vitro Techniques; N-Formylmethionine Leucyl-Phenylalanine; Neurotoxins; Pertussis Toxin; Phosphatidylinositols; Receptors, Fc; Receptors, Formyl Peptide; Receptors, IgG; Receptors, Immunologic; Ribonucleases; Tetradecanoylphorbol Acetate; Time Factors; Virulence Factors, Bordetella

1991
Differential inhibition and potentiation by cell-permeant analogues of cyclic AMP and cyclic GMP and NO-containing compounds of exocytosis in human neutrophils.
    Naunyn-Schmiedeberg's archives of pharmacology, 1991, Volume: 344, Issue:4

    Topics: 1-Methyl-3-isobutylxanthine; Calcium; Cell Aggregation; Complement C5a; Cyanides; Cyclic AMP; Cyclic GMP; Exocytosis; Glucuronidase; Humans; In Vitro Techniques; Methylene Blue; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Nitroprusside; Nitrous Oxide; Superoxide Dismutase

1991
Receptor-specific threshold effects of cyclic AMP are involved in the regulation of enzyme release and superoxide production from human neutrophils.
    Biochimica et biophysica acta, 1985, Aug-30, Volume: 846, Issue:2

    Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Alprostadil; Cyclic AMP; Dinoprost; Enzyme Activation; Humans; Isoproterenol; N-Formylmethionine Leucyl-Phenylalanine; Prostaglandin D2; Prostaglandins D; Prostaglandins E; Prostaglandins F; Receptors, Adrenergic, beta; Receptors, Cell Surface; Receptors, Prostaglandin; Receptors, Prostaglandin E; Superoxides

1985
Potentiation of PGE1-induced increase in cyclic AMP by chemotactic peptide and Ca2+ ionophore through calmodulin-dependent processes.
    Journal of immunology (Baltimore, Md. : 1950), 1987, Feb-15, Volume: 138, Issue:4

    Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Alprostadil; Animals; Calcimycin; Calmodulin; Colforsin; Cyclic AMP; Drug Synergism; Female; Guanosine Triphosphate; Guinea Pigs; Membrane Proteins; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Prostaglandin Antagonists; Sulfonamides; Tetradecanoylphorbol Acetate

1987
Methylxanthine bronchodilators potentiate multiple human neutrophil functions.
    Journal of immunology (Baltimore, Md. : 1950), 1987, Mar-15, Volume: 138, Issue:6

    Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adenosine Deaminase; Aminophylline; Bronchodilator Agents; Cell Aggregation; Chemotaxis, Leukocyte; Dose-Response Relationship, Drug; Humans; In Vitro Techniques; Lysosomes; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphodiesterase Inhibitors; Receptors, Purinergic; Superoxides; Theophylline; Xanthines

1987
Density heterogeneity of human lung mast cells.
    The Journal of allergy and clinical immunology, 1988, Volume: 82, Issue:1

    Topics: 1-Methyl-3-isobutylxanthine; Bucladesine; Calcimycin; Cell Count; Cell Separation; Histamine; Histamine Release; Humans; Isoproterenol; Lung; Masoprocol; Mast Cells; N-Formylmethionine Leucyl-Phenylalanine; p-Methoxy-N-methylphenethylamine; Prostaglandin D2; Prostaglandins D

1988
FMLP-induced arachidonic acid release, phospholipid metabolism, and calcium mobilization in human monocytes. Regulation by cyclic AMP.
    Inflammation, 1988, Volume: 12, Issue:3

    Topics: 1-Methyl-3-isobutylxanthine; Arachidonic Acid; Arachidonic Acids; Bucladesine; Calcimycin; Calcium; Cells, Cultured; Chromatography, Thin Layer; Cyclic AMP; Cytosol; Humans; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; Phospholipids

1988
Chemoattractant-elicited alterations of cAMP levels in human polymorphonuclear leukocytes require a Ca2+-dependent mechanism which is independent of transmembrane activation of adenylate cyclase.
    The Journal of biological chemistry, 1985, Jun-10, Volume: 260, Issue:11

    Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Alprostadil; Calcimycin; Calcium; Calmodulin; Cyclic AMP; Enzyme Activation; Gallic Acid; Humans; Isoproterenol; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Prostaglandins E

1985
The alterative effect of isobutylmethylxanthine in hypofunctional human neutrophil chemotaxis.
    Biochemical and biophysical research communications, 1982, Oct-15, Volume: 108, Issue:3

    Topics: 1-Methyl-3-isobutylxanthine; Adolescent; Adult; Chemotaxis, Leukocyte; Child; Female; Humans; Male; N-Formylmethionine; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oligopeptides; Periodontitis; Theophylline

1982
Autacoid and beta-adrenergic agonist modulation of N-formylmethionyl-leucyl-phenylalanine evoked lysosomal enzyme release from human neutrophils.
    Agents and actions, 1984, Volume: 14, Issue:3-4

    Topics: 1-Methyl-3-isobutylxanthine; Adrenergic beta-Agonists; Adult; Alprostadil; Autacoids; Calcimycin; Glucuronidase; Histamine; Humans; In Vitro Techniques; Lysosomes; Muramidase; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Prostaglandins E

1984
The mechanism of basophil histamine release induced by pepstatin A.
    Journal of immunology (Baltimore, Md. : 1950), 1984, Volume: 133, Issue:3

    Topics: 1-Methyl-3-isobutylxanthine; Adolescent; Adult; Alprostadil; Basophils; Bucladesine; Cross Reactions; Desensitization, Immunologic; Dose-Response Relationship, Immunologic; Histamine Release; Humans; Middle Aged; N-Formylmethionine Leucyl-Phenylalanine; Oligopeptides; Pepstatins; Prostaglandins E

1984
ADP-ribosylation of the specific membrane protein by islet-activating protein, pertussis toxin, associated with inhibition of a chemotactic peptide-induced arachidonate release in neutrophils. A possible role of the toxin substrate in Ca2+-mobilizing bios
    The Journal of biological chemistry, 1984, Nov-25, Volume: 259, Issue:22

    Topics: 1-Methyl-3-isobutylxanthine; Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Animals; Arachidonic Acid; Arachidonic Acids; Bacterial Toxins; Calcimycin; Calcium; Chemotaxis, Leukocyte; Cholera Toxin; Cyclic AMP; Dose-Response Relationship, Drug; Guinea Pigs; Male; Membrane Proteins; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Nucleoside Diphosphate Sugars; Pertussis Toxin; Superoxides; Virulence Factors, Bordetella

1984
Beta 2 integrin engagement triggers actin polymerization and phosphatidylinositol trisphosphate formation in non-adherent human neutrophils.
    The Journal of cell biology, 1993, Volume: 123, Issue:6 Pt 1

    Topics: 1-Methyl-3-isobutylxanthine; Actin Cytoskeleton; Actins; Antigens, CD; Calcium; CD18 Antigens; Cell Adhesion; Cyclic AMP; Humans; In Vitro Techniques; Integrins; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphatidylinositol Phosphates; Signal Transduction; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella

1993
Differential effects of cAMP-elevating drugs on stimulus-induced cytosolic calcium changes in human basophils.
    Journal of leukocyte biology, 1994, Volume: 55, Issue:6

    Topics: 1-Methyl-3-isobutylxanthine; Anti-Inflammatory Agents, Non-Steroidal; Basophils; Calcium; Colforsin; Cyclic AMP; Cytosol; Fluorescent Dyes; Fura-2; Histamine Release; Humans; Immunoglobulin E; In Vitro Techniques; Kinetics; Leukotrienes; Microscopy, Fluorescence; N-Formylmethionine Leucyl-Phenylalanine; Pyrrolidinones; Rolipram; Time Factors

1994
Two new formylated peptides able to activate chemotaxis and respiratory burst selectively as tools for studying human neutrophil responses.
    Cellular signalling, 1994, Volume: 6, Issue:1

    Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Cell Movement; Chemotaxis, Leukocyte; Cyclic AMP; Esters; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Respiratory Burst; Superoxides

1994
Cyclic AMP-increasing agents interfere with chemoattractant-induced respiratory burst in neutrophils as a result of the inhibition of phosphatidylinositol 3-kinase rather than receptor-operated Ca2+ influx.
    The Journal of biological chemistry, 1995, Oct-06, Volume: 270, Issue:40

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Arachidonic Acid; Biological Transport, Active; Calcium; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Guinea Pigs; In Vitro Techniques; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphatidylinositol 3-Kinases; Phosphotransferases (Alcohol Group Acceptor); Receptors, Formyl Peptide; Receptors, Immunologic; Receptors, Peptide; Respiratory Burst; Signal Transduction; Superoxides; Tetradecanoylphorbol Acetate

1995
Nitric oxide-generating system as an autocrine mechanism in human polymorphonuclear leucocytes.
    The Biochemical journal, 1993, Jun-15, Volume: 292 ( Pt 3)

    Topics: 1-Methyl-3-isobutylxanthine; Arginine; Biological Transport; Citrulline; Cyclic GMP; Endothelins; Humans; In Vitro Techniques; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Nitric Oxide; Nitroprusside; omega-N-Methylarginine

1993
Inhibition of the production of platelet activating factor and of leukotriene B4 in activated neutrophils by nimesulide due to an elevation of intracellular cyclic adenosine monophosphate.
    Arzneimittel-Forschung, 1995, Volume: 45, Issue:10

    Topics: 1-Methyl-3-isobutylxanthine; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cytochalasin B; Enzyme Inhibitors; Humans; In Vitro Techniques; Isoquinolines; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphodiesterase Inhibitors; Platelet Activating Factor; Protein Kinase Inhibitors; Sulfonamides; Zymosan

1995
Synergistic inhibition of human polymorphonuclear function by prostaglandin E1 and linsidomine.
    The Journal of pharmacy and pharmacology, 1996, Volume: 48, Issue:7

    Topics: 1-Methyl-3-isobutylxanthine; Alprostadil; Cyclic AMP; Drug Synergism; Humans; Molsidomine; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphodiesterase Inhibitors; Platelet Aggregation Inhibitors; Respiratory Burst

1996
Regulation of superoxide production in human polymorphonuclear leukocytes (PMNs).
    Biochemical Society transactions, 1997, Volume: 25, Issue:2

    Topics: 1-Methyl-3-isobutylxanthine; Colforsin; Cyclic AMP; Cytochalasin B; Dinoprostone; Epinephrine; Humans; In Vitro Techniques; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Superoxides

1997
Dual action of cAMP-dependent protein kinase on granulocyte movement.
    Biochemical and biophysical research communications, 1997, Jun-27, Volume: 235, Issue:3

    Topics: 1-Methyl-3-isobutylxanthine; Actins; Antibodies, Monoclonal; CD18 Antigens; Chemotaxis, Leukocyte; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Granulocytes; HL-60 Cells; Humans; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Thionucleotides

1997
The effect of pentoxifylline on human neutrophil migration: a possible role for cyclic nucleotides.
    Biochemical pharmacology, 1997, Aug-15, Volume: 54, Issue:4

    Topics: 1-Methyl-3-isobutylxanthine; Calcium; Cell Movement; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pentoxifylline

1997
Extracellular ATP couples to cAMP generation and granulocytic differentiation in human NB4 promyelocytic leukaemia cells.
    Immunology and cell biology, 2000, Volume: 78, Issue:5

    Topics: 1-Methyl-3-isobutylxanthine; Adenine Nucleotides; Adenosine Diphosphate; Adenosine Triphosphate; Antigens, CD; Blotting, Northern; Cell Differentiation; Cell Size; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Enzyme Activation; Granulocytes; HL-60 Cells; Humans; Leukemia, Promyelocytic, Acute; N-Formylmethionine Leucyl-Phenylalanine; Phosphodiesterase Inhibitors; Receptors, Formyl Peptide; Receptors, Immunologic; Receptors, Peptide; Receptors, Purinergic P2; Reverse Transcriptase Polymerase Chain Reaction; Thionucleotides; Tretinoin; Tumor Cells, Cultured

2000
Evaluation of signal transduction pathways in chemoattractant-induced human monocyte chemotaxis.
    Inflammation, 2001, Volume: 25, Issue:2

    Topics: 1-Methyl-3-isobutylxanthine; Androstadienes; Chemokine CCL2; Chemokine CCL3; Chemokine CCL4; Chemokine CCL5; Chemotactic Factors; Chemotaxis, Leukocyte; Chromones; Colforsin; Flavonoids; Humans; In Vitro Techniques; Macrophage Inflammatory Proteins; Mitogen-Activated Protein Kinases; Monocytes; Morpholines; N-Formylmethionine Leucyl-Phenylalanine; Phosphatidylinositol 3-Kinases; Signal Transduction; Wortmannin

2001
Physiologic responses to small emboli and hemodynamic effects of changes in deformability of polymorphonuclear leukocytes in isolated rabbit lung.
    Microvascular research, 2002, Volume: 63, Issue:1

    Topics: 1-Methyl-3-isobutylxanthine; Actins; Animals; Arteries; Cytochalasin D; Hemodynamics; Kinetics; Lipopolysaccharides; Lung; Microcirculation; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Peroxidase; Rabbits; Time Factors

2002
Nitrolinoleate inhibits superoxide generation, degranulation, and integrin expression by human neutrophils: novel antiinflammatory properties of nitric oxide-derived reactive species in vascular cells.
    Circulation research, 2002, Sep-06, Volume: 91, Issue:5

    Topics: 1-Methyl-3-isobutylxanthine; Anti-Inflammatory Agents; Calcium; Cell Degranulation; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Humans; Integrins; Linoleic Acid; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; Neutrophils; Nitro Compounds; Phosphodiesterase Inhibitors; Superoxides; Tetradecanoylphorbol Acetate

2002
The immune modulator FTY720 targets sphingosine-kinase-dependent migration of human monocytes in response to amyloid beta-protein and its precursor.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2004, Volume: 18, Issue:11

    Topics: 1-Methyl-3-isobutylxanthine; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Androstadienes; Bombesin; Calcitonin Gene-Related Peptide; Cell Movement; Chemotaxis, Leukocyte; Cholera Toxin; Drug Evaluation, Preclinical; Enzyme Inhibitors; Fingolimod Hydrochloride; Gene Expression Regulation; Heterotrimeric GTP-Binding Proteins; Humans; Immunologic Factors; Indoles; Leukocytes, Mononuclear; Maleimides; N-Formylmethionine Leucyl-Phenylalanine; Neuropeptides; Pertussis Toxin; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Propylene Glycols; Protein Kinase Inhibitors; Protein Processing, Post-Translational; Receptors, Lysosphingolipid; RNA, Messenger; Secretogranin II; Sphingosine; Staurosporine; Tyrphostins; Vasoactive Intestinal Peptide; Wortmannin

2004