1-methyl-3-isobutylxanthine and h 89

Topics: Animals; Calcium; Calophyllum; Cyclic AMP-Dependent Protein Kinases; Isoproterenol; Muscle, Smooth, Vascular; Phenylephrine; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Plant Bark; Rats; Vasodilation; Vasodilator Agents

Topics: 1-Methyl-3-isobutylxanthine; Amiloride; Animals; Cell Communication; Cells, Cultured; Cyclic AMP; Dose-Response Relationship, Drug; Gap Junctions; Gastric Mucosa; Isoproterenol; Isoquinolines; Nigericin; Propranolol; Rabbits; Receptors, Adrenergic, beta; Sulfonamides

Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Animals; Brain; Brain Neoplasms; Cloning, Molecular; Colforsin; Creatine Kinase; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Energy Metabolism; Enzyme Activation; Enzyme Induction; Glioblastoma; Glioma; HeLa Cells; Humans; Isoenzymes; Isoquinolines; Myelin Sheath; Nerve Tissue Proteins; Neuroglia; Protein Synthesis Inhibitors; Rats; Recombinant Fusion Proteins; RNA, Antisense; Sulfonamides; Transcription, Genetic; Transfection; Tumor Cells, Cultured

Topics: 1-Methyl-3-isobutylxanthine; 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dopamine Agonists; Ergolines; Goldfish; Growth Hormone; In Vitro Techniques; Indicators and Reagents; Isoquinolines; Pituitary Gland; Quinpirole; Receptors, Dopamine D1; Sulfonamides

Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Animals; Bucladesine; Calcium; Cell Membrane; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Fertilization in Vitro; Immunoblotting; Isoquinolines; Male; Mice; Phosphorylation; Protein Kinase Inhibitors; Sodium Bicarbonate; Sperm Capacitation; Spermatozoa; Sulfonamides; Tyrosine

Topics: 1-Methyl-3-isobutylxanthine; Animals; Arachidonic Acid; Arginine Vasopressin; Bradykinin; Calcimycin; Cell Line; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Diglycerides; Dogs; Enzyme Activation; Enzyme Inhibitors; Estrenes; Inositol Phosphates; Ionophores; Isoquinolines; Kidney; Pyrrolidinones; Sulfonamides; Type C Phospholipases

Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Animals; Aorta; Binding, Competitive; Bucladesine; Colforsin; Cyclic AMP-Dependent Protein Kinases; Drug Interactions; Enzyme Activation; Enzyme Inhibitors; Guanidines; In Vitro Techniques; Isoquinolines; Isotope Labeling; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Phosphodiesterase Inhibitors; Potassium Channels; Pyridines; Rats; Rats, Sprague-Dawley; Rubidium; Sulfonamides; Vasodilator Agents

Topics: 1-Methyl-3-isobutylxanthine; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cytochalasin B; Enzyme Inhibitors; Humans; In Vitro Techniques; Isoquinolines; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphodiesterase Inhibitors; Platelet Activating Factor; Protein Kinase Inhibitors; Sulfonamides; Zymosan

Topics: 1-Methyl-3-isobutylxanthine; Animals; Bucladesine; Colforsin; Cyclic AMP; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Glucose; Hexokinase; Hexoses; Isoquinolines; Liver Neoplasms, Experimental; Mannoheptulose; Promoter Regions, Genetic; Rats; Signal Transduction; Sulfonamides; Transfection; Tumor Cells, Cultured

Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Bucladesine; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Drug Synergism; Enzyme Activation; Female; Isoquinolines; Moths; Nucleotides, Cyclic; Oviducts; Phosphodiesterase Inhibitors; Sulfonamides; Vitellogenins

Topics: 1-Methyl-3-isobutylxanthine; Alkaloids; Analysis of Variance; Animals; Carbazoles; Dose-Response Relationship, Drug; Indoles; Isoquinolines; Naphthalenes; Neurons; Neuropeptides; Neurotransmitter Agents; Patch-Clamp Techniques; Phosphodiesterase Inhibitors; Protein Kinase C; Protein Kinase Inhibitors; Signal Transduction; Snails; Sulfonamides; Vasodilator Agents

Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Carbazoles; Chickens; Cochlea; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; DNA Replication; Enzyme Activation; Enzyme Inhibitors; Gentamicins; Hair Cells, Auditory; Hearing Loss, Sensorineural; Indoles; Isoquinolines; Organ Culture Techniques; Pyrroles; Regeneration; Signal Transduction; Sulfonamides

Topics: 1-Methyl-3-isobutylxanthine; Animals; Biological Transport; Cell Compartmentation; Cell Membrane; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Endoplasmic Reticulum; Enzyme Inhibitors; Exocytosis; Golgi Apparatus; Hexosaminidases; Isoquinolines; Membrane Glycoproteins; Microscopy, Electron; Protein Processing, Post-Translational; Rats; Sulfonamides; Viral Envelope Proteins

Topics: 1-Methyl-3-isobutylxanthine; Amino Acid Sequence; Animals; Antibodies; Base Sequence; Cell Line; Cells, Cultured; Conserved Sequence; DNA Primers; Enzyme Inhibitors; Epithelium; Female; Gene Expression; Genistein; Isoflavones; Isoquinolines; Kinetics; Mammary Glands, Animal; Mice; Molecular Sequence Data; Mucin-1; Naphthalenes; Peptide Fragments; Polymerase Chain Reaction; Pregnancy; Protein Biosynthesis; Protein-Tyrosine Kinases; Recombinant Fusion Proteins; RNA, Messenger; Staurosporine; Sulfonamides; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transfection; Uterus

Topics: 1-Methyl-3-isobutylxanthine; Acrosome; Animals; Blotting, Western; Cattle; Culture Media; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Glucose; Heparin; In Vitro Techniques; Isoquinolines; Male; Phosphodiesterase Inhibitors; Phosphorylation; Protein Tyrosine Phosphatases; Sperm Capacitation; Sulfonamides

Topics: 1-Methyl-3-isobutylxanthine; Animals; Blotting, Northern; Cardiomegaly; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Gene Expression; Genes, fos; Glucagon; Isoquinolines; Male; Perfusion; Phosphodiesterase Inhibitors; Pressure; Protein Biosynthesis; Protein Kinase C; Rats; Rats, Sprague-Dawley; Sulfonamides

Topics: 1-Methyl-3-isobutylxanthine; Animals; Cattle; Cells, Cultured; Colforsin; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Female; Indoles; Isoquinolines; Maleimides; Meiosis; Oocytes; Phorbol Esters; Protein Kinase C; Signal Transduction; Sulfonamides; Time Factors

Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Animals; Cattle; Cell Communication; Cells, Cultured; Colforsin; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Female; In Vitro Techniques; Isoquinolines; Meiosis; Oocytes; Oogenesis; Phosphodiesterase Inhibitors; Signal Transduction; Sulfonamides; Theca Cells

Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 1-Methyl-3-isobutylxanthine; Animals; Calcium; Calcium Channel Blockers; Cell Line; Chloride Channels; Chlorides; Cyclic AMP; Cytosol; Enzyme Inhibitors; Epithelium; Ion Transport; Isoquinolines; Kidney; Kinetics; Nitrobenzoates; Phosphodiesterase Inhibitors; Protein Kinase Inhibitors; Sulfonamides; Xenopus laevis

Topics: 1-Methyl-3-isobutylxanthine; Animals; COS Cells; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Epidermal Growth Factor; Estradiol; Gene Expression Regulation, Developmental; Genes, Reporter; HeLa Cells; Humans; Isoquinolines; Point Mutation; Promoter Regions, Genetic; Receptors, Estrogen; Sulfonamides; Transcriptional Activation; Transfection

Topics: 1-Methyl-3-isobutylxanthine; Animals; Base Sequence; Bone Neoplasms; Cyclic AMP; Dose-Response Relationship, Drug; Drug Synergism; Gene Deletion; Gene Expression Regulation; Genes, Reporter; Humans; Isoquinolines; Luciferases; Molecular Sequence Data; Osteocalcin; Osteosarcoma; Parathyroid Hormone; Phosphodiesterase Inhibitors; Promoter Regions, Genetic; Protein Kinase Inhibitors; Rats; Sulfonamides; Teriparatide; Time Factors; Transcription, Genetic; Transfection; Tumor Cells, Cultured

Topics: 1-Methyl-3-isobutylxanthine; Cations; Cell Line; Cyclic AMP; Cytochalasin D; Enzyme Inhibitors; Epithelial Cells; Epithelium; Ion Channels; Isoquinolines; Kidney; Kinetics; Patch-Clamp Techniques; Permeability; Phosphodiesterase Inhibitors; Phosphorylation; Physical Stimulation; Sodium; Sulfonamides

Topics: 1-Methyl-3-isobutylxanthine; alpha-MSH; Animals; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Isoquinolines; Melanophores; Okadaic Acid; Oryzias; Phosphodiesterase Inhibitors; Phosphoprotein Phosphatases; Pigments, Biological; Signal Transduction; Sulfonamides

Topics: 1-Methyl-3-isobutylxanthine; Adrenergic beta-Agonists; Alanine; Animals; Cell Line; Colforsin; COS Cells; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Isoproterenol; Isoquinolines; Macromolecular Substances; Mutagenesis, Site-Directed; Okadaic Acid; Phosphorylation; Point Mutation; Rats; Recombinant Proteins; Rubidium; Serine; Sodium-Potassium-Exchanging ATPase; Spodoptera; Sulfonamides; Transfection

Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Adenylyl Cyclases; Animals; Brain; Calcium-Calmodulin-Dependent Protein Kinases; Capillaries; Cattle; Cell Division; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Endothelial Growth Factors; Endothelium, Vascular; Enzyme Inhibitors; Fibroblast Growth Factor 2; Isoproterenol; Isoquinolines; Lymphokines; Phosphodiesterase Inhibitors; Proto-Oncogene Proteins c-raf; Signal Transduction; Sulfonamides; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors

Topics: 1-Methyl-3-isobutylxanthine; Animals; Calcitonin Gene-Related Peptide; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Isoquinolines; Lipopolysaccharides; Macrophages, Peritoneal; Male; Mice; Mice, Inbred BALB C; Recombinant Proteins; Sulfonamides; Tumor Necrosis Factor-alpha

Topics: 1-Methyl-3-isobutylxanthine; Biological Transport; Bucladesine; Cell Line; Cholera Toxin; Colforsin; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Epithelial Cells; Genistein; Humans; Isoquinolines; Kidney Tubules, Proximal; Kinetics; Nitriles; Protein Kinase C; Protein-Tyrosine Kinases; Riboflavin; Sulfonamides; Temperature; Tyrphostins

Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Ambystoma; Animals; Colforsin; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Glycine; Glycine Agents; Isoquinolines; Kinetics; Kynurenic Acid; Membrane Potentials; Patch-Clamp Techniques; Phosphodiesterase Inhibitors; Protein Kinase C; Retinal Ganglion Cells; Strychnine; Sulfonamides

Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Adrenergic beta-Antagonists; Animals; Aorta; Calcimycin; Cell Line; Cholera Toxin; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Endothelium, Vascular; Enhancer Elements, Genetic; Enzyme Inhibitors; Gene Expression Regulation; Genes, Reporter; Isoproterenol; Isoquinolines; Kinetics; Luciferases; Rabbits; Signal Transduction; Sulfonamides; Transfection

Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Bradykinin; Calcium; Chlorides; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cytochrome P-450 Enzyme Inhibitors; Enzyme Inhibitors; In Vitro Techniques; Indoles; Isoquinolines; Kidney Cortex; Kidney Medulla; Kidney Tubules; Male; Maleimides; Neomycin; Perfusion; Phospholipases A; Phospholipases A2; Protein Kinase C; Rats; Rats, Sprague-Dawley; Sulfonamides; Vasopressins

Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Barium; Cantharidin; Chloride Channels; Chlorides; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; gamma-Aminobutyric Acid; Grasshoppers; Irritants; Isoquinolines; Membrane Potentials; Muscles; Neurons; Octopamine; Phosphodiesterase Inhibitors; Phosphoric Monoester Hydrolases; Potassium; Potassium Channels; Sulfonamides; Synaptic Transmission

Topics: 1-Methyl-3-isobutylxanthine; Animals; Blood Pressure; Cardiomegaly; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Gene Expression; Glucagon; HSP70 Heat-Shock Proteins; Hypertension; In Vitro Techniques; Isoquinolines; Male; Myocardium; Naphthalenes; Perfusion; Protein Biosynthesis; Protein Kinase C; Rats; Rats, Sprague-Dawley; RNA, Messenger; Signal Transduction; Sulfonamides

Topics: 1-Methyl-3-isobutylxanthine; Animals; Biotinylation; CHO Cells; Colforsin; Cricetinae; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Humans; Isoquinolines; Microscopy, Fluorescence; Receptors, G-Protein-Coupled; Receptors, Gastrointestinal Hormone; Secretin; Signal Transduction; Sulfonamides; Transfection

Topics: 1-Methyl-3-isobutylxanthine; Animals; Bumetanide; Carrier Proteins; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Enzyme Inhibitors; Female; Isomerism; Isoquinolines; Loop of Henle; Mice; Oocytes; Phosphodiesterase Inhibitors; Sodium-Potassium-Chloride Symporters; Sulfonamides; Xenopus laevis

Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Adenylyl Cyclases; Animals; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Cesium; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dihydropyridines; Drosophila; Enzyme Inhibitors; Isoquinolines; Larva; Membrane Potentials; Muscles; Mutagenesis; Nervous System; Phosphodiesterase Inhibitors; Sulfonamides

Topics: 1-Methyl-3-isobutylxanthine; Adrenocorticotropic Hormone; Alkaline Phosphatase; Animals; Cells, Cultured; Chloride Channels; Chlorides; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Electric Conductivity; Female; Isoquinolines; Patch-Clamp Techniques; Phosphorylation; Rats; Rats, Long-Evans; Sulfonamides; Zona Glomerulosa

Topics: 1-Methyl-3-isobutylxanthine; Breast Neoplasms; Cell Cycle Proteins; Cholera Toxin; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinase Inhibitor p27; Cyclin-Dependent Kinases; Cyclins; Female; Humans; Isoquinolines; Kinetics; Lovastatin; Microtubule-Associated Proteins; Protein Processing, Post-Translational; Sulfonamides; Transfection; Tumor Cells, Cultured; Tumor Suppressor Proteins

Topics: 1-Methyl-3-isobutylxanthine; Animals; Calcium; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dextromethorphan; Enzyme Inhibitors; Estrenes; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Isoquinolines; Models, Neurological; Necturus; Pyrrolidinones; Ryanodine; Signal Transduction; Sulfonamides; Taste; Taste Buds; Thapsigargin; Thionucleotides; Type C Phospholipases

Topics: 1-Methyl-3-isobutylxanthine; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; 8-Bromo Cyclic Adenosine Monophosphate; Arginase; Caco-2 Cells; Colforsin; Cyclic AMP; Enzyme Induction; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Humans; Isoenzymes; Isoquinolines; Kinetics; Okadaic Acid; Protein Biosynthesis; RNA, Messenger; Sulfonamides; Transcription, Genetic

Topics: 1-Methyl-3-isobutylxanthine; Animals; Biological Transport; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Calmodulin; Cell Fractionation; Cells, Cultured; Chelating Agents; Cholecystokinin; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Duodenum; Egtazic Acid; Enzyme Inhibitors; Intestinal Mucosa; Isoquinolines; Oleic Acid; Phosphodiesterase Inhibitors; Protein Kinase C; Rats; Secretin; Sulfonamides; Tetradecanoylphorbol Acetate

Topics: 1-Methyl-3-isobutylxanthine; Adenine; Adenylyl Cyclase Inhibitors; Adrenal Cortex; Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Animals; Corticosterone; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Endothelin-1; Enzyme Inhibitors; Humans; Hydrocortisone; Isoquinolines; Male; Protein-Tyrosine Kinases; Rats; Rats, Sprague-Dawley; Sulfonamides; Tyrphostins

Topics: 1-Methyl-3-isobutylxanthine; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Electron Spin Resonance Spectroscopy; Humans; Hydrazines; Isoquinolines; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitrogen Oxides; omega-N-Methylarginine; Phosphodiesterase Inhibitors; Phosphorylation; Signal Transduction; Sperm Capacitation; Spermatozoa; Spermine; Sulfonamides; Tyrosine

Topics: 1-Methyl-3-isobutylxanthine; Alternative Splicing; Animals; Biological Transport; Bumetanide; Carrier Proteins; Cell Membrane; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cytosol; Diuretics; Enzyme Inhibitors; Female; Furosemide; Gene Expression; Hypotonic Solutions; Isomerism; Isoquinolines; Loop of Henle; Mammals; Oocytes; Osmolar Concentration; Phosphodiesterase Inhibitors; Sodium Radioisotopes; Sodium-Potassium-Chloride Symporters; Sulfonamides; Tritium; Xenopus laevis

Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 1-Methyl-3-isobutylxanthine; Adenosine Triphosphate; Animals; Autocrine Communication; Calcium; Calcium Channels, L-Type; Cattle; Cells, Cultured; Chromaffin Cells; Colforsin; Cyclic AMP; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enzyme Inhibitors; GABA Antagonists; Isoquinolines; Kinetics; Naloxone; Narcotic Antagonists; Patch-Clamp Techniques; Picrotoxin; Protein Kinase Inhibitors; Sulfonamides; Suramin

Topics: 1-Methyl-3-isobutylxanthine; Animals; beta-Cyclodextrins; Bucladesine; Cells, Cultured; Culture Media; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclodextrins; Enzyme Inhibitors; Glycoproteins; Isoquinolines; Male; Marine Toxins; Oxazoles; Phosphoprotein Phosphatases; Serum Albumin; Signal Transduction; Sperm Agglutination; Sperm Capacitation; Sperm Motility; Spermatozoa; Sulfonamides; Swine; Thionucleotides

Topics: 1-Methyl-3-isobutylxanthine; Adrenergic beta-Agonists; Animals; Calcium Signaling; Carbachol; Chlorides; Cholinergic Agonists; Colforsin; Cyclic AMP; Enzyme Inhibitors; Gastrointestinal Agents; Isoproterenol; Isoquinolines; Membrane Potentials; Pancreas; Patch-Clamp Techniques; Phosphodiesterase Inhibitors; Potassium Channels; Rats; Secretin; Sulfonamides; Vasoactive Intestinal Peptide

Topics: 1-Methyl-3-isobutylxanthine; Animals; Cells, Cultured; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dinoprostone; Dose-Response Relationship, Drug; Endothelial Growth Factors; Enzyme Inhibitors; Fatty Acids, Omega-3; Fatty Acids, Omega-6; Fatty Acids, Unsaturated; Female; Isoquinolines; Kinetics; Lymphokines; Macrophages; Mice; Mice, Inbred BALB C; Phosphodiesterase Inhibitors; RNA, Messenger; Sulfonamides; Transcriptional Activation; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors

Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Adipose Tissue, Brown; Animals; Calcium; Calcium Signaling; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Fura-2; In Vitro Techniques; Isoquinolines; Male; Mice; Mice, Inbred Strains; Okadaic Acid; Phosphodiesterase Inhibitors; Sulfonamides

Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Adenylyl Cyclases; Adrenocorticotropic Hormone; Aging; Animals; Carrier Proteins; Colforsin; Corticosterone; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Desoxycorticosterone; Female; Intracellular Signaling Peptides and Proteins; Isoquinolines; Ovariectomy; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Prolactin; Rats; Rats, Sprague-Dawley; Sulfonamides; Zona Fasciculata; Zona Reticularis

Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Bucladesine; Carbazoles; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Flavonoids; Genistein; Indoles; Isoquinolines; MAP Kinase Signaling System; Muscle, Smooth, Vascular; Phosphodiesterase Inhibitors; Phosphorylation; Plasminogen Activator Inhibitor 1; Protein Kinase C; Protein-Tyrosine Kinases; Pyrroles; Rats; Signal Transduction; src-Family Kinases; Stilbenes; Sulfonamides; Tissue Plasminogen Activator; Urokinase-Type Plasminogen Activator

Topics: 1-Methyl-3-isobutylxanthine; Alkaloids; Amino Acid Motifs; Benzophenanthridines; Bucladesine; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Female; Fetal Blood; Flavonoids; Follicular Fluid; Humans; Isoquinolines; Male; MAP Kinase Kinase Kinase 1; Phenanthridines; Phosphorylation; Progesterone; Protein Kinase C; Protein Serine-Threonine Kinases; Seminal Plasma Proteins; Signal Transduction; Sperm Capacitation; Sulfonamides; Tyrosine; Tyrphostins

Topics: 1-Methyl-3-isobutylxanthine; Animals; Calcimycin; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Carps; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Enzyme Activators; Enzyme Inhibitors; Growth Hormone; Imines; In Vitro Techniques; Ionophores; Isoquinolines; Neuropeptides; Neurotransmitter Agents; Nifedipine; Phosphodiesterase Inhibitors; Pituitary Adenylate Cyclase-Activating Polypeptide; Pituitary Gland; Signal Transduction; Sulfonamides; Vasoactive Intestinal Peptide

Topics: 1-Methyl-3-isobutylxanthine; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adipocytes; Adipose Tissue, Brown; Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Animals; Calcium Signaling; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Isoproterenol; Isoquinolines; Male; Mice; Mice, Inbred Strains; Norepinephrine; Phosphodiesterase Inhibitors; Quinolones; Receptors, Adrenergic, beta; Sulfonamides; Thapsigargin

Topics: 1-Methyl-3-isobutylxanthine; Amyloid; Animals; CCAAT-Binding Factor; Cell Line; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; DNA-Binding Proteins; Gene Expression Regulation; Hepatocyte Nuclear Factor 1; Hepatocyte Nuclear Factor 1-alpha; Insulin; Islet Amyloid Polypeptide; Islets of Langerhans; Isoquinolines; Mutagenesis, Site-Directed; Nuclear Proteins; Phosphodiesterase Inhibitors; Promoter Regions, Genetic; Protein Binding; Rats; Sulfonamides; Transcription Factors

Topics: 1-Methyl-3-isobutylxanthine; Animals; Apoptosis; Carbazoles; Cell Line; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guanine Nucleotide Exchange Factors; Indoles; Islets of Langerhans; Isoquinolines; Mice; Palmitates; Pyrroles; Signal Transduction; Sulfonamides

Topics: 1-Methyl-3-isobutylxanthine; Adrenocorticotropic Hormone; Animals; Calcium Channel Blockers; Cell Line; Cells, Cultured; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Humans; Insulin; Insulin Secretion; Insulinoma; Islets of Langerhans; Isoquinolines; Mice; Nitrendipine; Paracrine Communication; Phosphodiesterase Inhibitors; Receptor, Melanocortin, Type 2; RNA, Messenger; Stimulation, Chemical; Sulfonamides; Thionucleotides

Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Adult; Anti-Ulcer Agents; Bucladesine; Cyclic AMP; Cyclic Nucleotide Phosphodiesterases, Type 1; Cyclic Nucleotide Phosphodiesterases, Type 4; Dose-Response Relationship, Drug; Gastric Mucosa; Humans; Isoenzymes; Isoquinolines; Neutrophils; Rolipram; Sulfonamides; Superoxides; Triazines

Topics: 1-Methyl-3-isobutylxanthine; Animals; Catfishes; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Female; In Vitro Techniques; Isoquinolines; Kinetics; Naphthalenes; Phosphodiesterase Inhibitors; Prosencephalon; Protein Kinase C; Protein Kinase Inhibitors; Signal Transduction; Sulfonamides; Theophylline; Triiodothyronine; Tyrosine 3-Monooxygenase

Topics: 1-Methyl-3-isobutylxanthine; Amino Acid Sequence; Animals; Bone Morphogenetic Protein 2; Bone Morphogenetic Proteins; Catecholamines; Cell Differentiation; Cell Line; Cells, Cultured; Central Nervous System; Chick Embryo; Coturnix; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Drug Synergism; Enzyme Activation; Enzyme Inhibitors; Fibroblasts; Gene Expression; Genetic Vectors; Homeodomain Proteins; Humans; Isoquinolines; Molecular Sequence Data; Neural Crest; Neurons; Okadaic Acid; Phosphoprotein Phosphatases; Phosphorylation; RNA, Messenger; Sequence Alignment; Signal Transduction; Sulfonamides; Sympathetic Nervous System; Transcription, Genetic; Transfection; Transforming Growth Factor beta

Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; ATP Binding Cassette Transporter, Subfamily B; ATP-Binding Cassette Sub-Family B Member 4; Cells, Cultured; CREB-Binding Protein; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Gene Expression Regulation; Genes, Reporter; Hepatocytes; Isoquinolines; Male; Misoprostol; Rats; Rats, Wistar; Receptors, Prostaglandin E; Signal Transduction; Sulfonamides; Transcriptional Activation

Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Adenylyl Cyclases; Animals; Antidiuretic Hormone Receptor Antagonists; Benzazepines; Biological Transport; Cell Line; Colforsin; Cyclic AMP; Dogs; Drug Synergism; Enzyme Activation; Isoquinolines; Kidney; Membrane Transport Proteins; Phosphodiesterase Inhibitors; Protein Kinase Inhibitors; Sulfonamides; Transfection; Urea; Urea Transporters; Vasopressins

Topics: 1-Methyl-3-isobutylxanthine; Animals; Catfishes; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Estradiol; Female; Isoquinolines; Okadaic Acid; Oocytes; Ovarian Follicle; Phosphodiesterase Inhibitors; Phosphoprotein Phosphatases; Protein Kinase Inhibitors; Protein Phosphatase 1; Signal Transduction; Sulfonamides

Topics: 1-Methyl-3-isobutylxanthine; A Kinase Anchor Proteins; Adaptor Proteins, Signal Transducing; Animals; Blotting, Western; Cells, Cultured; Cyclic AMP; Cyclic AMP-Dependent Protein Kinase RIalpha Subunit; Cyclic AMP-Dependent Protein Kinase RIIalpha Subunit; Cyclic AMP-Dependent Protein Kinase Type II; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Enzyme Inhibitors; Female; Fluorescent Antibody Technique; Isoquinolines; Maturation-Promoting Factor; Meiosis; Oocytes; Oogenesis; Protein Kinases; Rats; Sulfonamides

Topics: 1-Methyl-3-isobutylxanthine; Animals; Arginine; Bucladesine; Buffaloes; Cell Survival; Cells, Cultured; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fluorescent Antibody Technique; Heparin; Isoquinolines; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Osmolar Concentration; Phosphodiesterase Inhibitors; Phosphoproteins; Phosphorylation; Protein Kinase Inhibitors; Sperm Capacitation; Sperm Motility; Spermatozoa; Sulfonamides; Tyrosine

Topics: 1-Methyl-3-isobutylxanthine; 4-Aminopyridine; Action Potentials; Animals; Colforsin; Cyclic AMP-Dependent Protein Kinases; Embryo, Nonmammalian; Female; Isoquinolines; Male; Muscle Fibers, Fast-Twitch; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Stimulation, Chemical; Sulfonamides; Zebrafish

Topics: 1-Methyl-3-isobutylxanthine; 3T3-L1 Cells; Adipogenesis; Animals; Cell Differentiation; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dexamethasone; Fibroblasts; Insulin; Isoquinolines; Mice; Mitosis; Protein Kinase Inhibitors; Signal Transduction; Sulfonamides; Theophylline

Topics: 1-Methyl-3-isobutylxanthine; Animals; Brain; Calcium; Catfishes; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Female; Fossils; In Vitro Techniques; Isoquinolines; Naphthalenes; Protein Kinase C; Seasons; Signal Transduction; Sulfonamides; Tyrosine 3-Monooxygenase

Topics: 1-Methyl-3-isobutylxanthine; Animals; Carrier Proteins; Cell Line, Tumor; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Exocytosis; Glucose; Green Fluorescent Proteins; Immunoblotting; Insulin; Insulin Secretion; Insulin-Secreting Cells; Insulinoma; Isoquinolines; Mice; Microscopy, Fluorescence; Microscopy, Immunoelectron; Mitochondrial Proteins; Okadaic Acid; Phosphorylation; Protein Transport; rab GTP-Binding Proteins; Recombinant Fusion Proteins; Reverse Transcriptase Polymerase Chain Reaction; Sulfonamides; Transfection

Topics: 1-Methyl-3-isobutylxanthine; Animals; Cell Membrane; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Exocytosis; Guanine Nucleotide Exchange Factors; Isoquinolines; Male; Rats; Rats, Sprague-Dawley; Sodium-Potassium-Chloride Symporters; Sodium-Potassium-Exchanging ATPase; Solute Carrier Family 12, Member 1; Sulfonamides

Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Cell Differentiation; Cell Line, Tumor; Colforsin; Cyclic GMP; Enzyme Inhibitors; Exocytosis; Humans; Isoquinolines; Microtubule-Associated Proteins; Neurons; Nitric Oxide; Nitric Oxide Synthase Type I; Nitroso Compounds; Nucleotides, Cyclic; Phosphodiesterase Inhibitors; Pyridinium Compounds; Quaternary Ammonium Compounds; Signal Transduction; Sulfonamides; Synapsins; Synaptic Vesicles; Synaptotagmin I; Teratocarcinoma; Time Factors

Topics: 1-Methyl-3-isobutylxanthine; 3T3-L1 Cells; Adipocytes; Adipokines; Adiponectin; Animals; Colforsin; Cyclic AMP-Dependent Protein Kinases; Exenatide; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Inflammation; Insulin Resistance; Isoquinolines; Mice; Peptides; Phosphodiesterase Inhibitors; Protein Kinase Inhibitors; Receptors, Glucagon; RNA, Messenger; Sulfonamides; Venoms

Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Animals; Cell Line; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Gonadotropin-Releasing Hormone; Humans; Isoquinolines; Neurons; Phosphodiesterase Inhibitors; Protein Kinase Inhibitors; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Sulfonamides

Topics: 1-Methyl-3-isobutylxanthine; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Brain Neoplasms; Cell Cycle Checkpoints; Cell Line, Tumor; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic Nucleotide Phosphodiesterases, Type 4; Dose-Response Relationship, Drug; Glioblastoma; Guanine Nucleotide Exchange Factors; Humans; Isoquinolines; Phosphodiesterase Inhibitors; Phosphorylation; Protein Kinase Inhibitors; Rolipram; Shelterin Complex; Signal Transduction; Sulfonamides; Telomere-Binding Proteins; Theophylline

Topics: 1-Methyl-3-isobutylxanthine; Anaphase; Animals; Asymmetric Cell Division; Bucladesine; Cell Movement; Cells, Cultured; Chromosomes, Mammalian; Cyclic AMP; Cytokinesis; Female; Intracellular Space; Isoquinolines; Meiosis; Mice; Mice, Inbred ICR; Microinjections; Myosin Type II; Oocytes; Sulfonamides

Topics: 1-Methyl-3-isobutylxanthine; 3T3 Cells; Adipocytes; Adipogenesis; Animals; Azacitidine; Cells, Cultured; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Decitabine; Dexamethasone; DNA Methylation; Female; Gene Expression Regulation; Glucocorticoids; Insulin; Isoquinolines; Mice; Mice, Inbred C57BL; Phosphodiesterase Inhibitors; Proteins; Sulfonamides; Up-Regulation

Topics: 1-Methyl-3-isobutylxanthine; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic Nucleotide Phosphodiesterases, Type 4; Enzyme Inhibitors; Isoproterenol; Isoquinolines; Loop of Henle; Male; Models, Animal; Phosphodiesterase Inhibitors; Propranolol; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Sodium Chloride; Sodium-Potassium-Chloride Symporters; Solute Carrier Family 12, Member 1; Sulfonamides

Topics: 1-Methyl-3-isobutylxanthine; Amino Acid Sequence; Animals; Chlorocebus aethiops; Colforsin; COS Cells; Cyclic AMP-Dependent Protein Kinases; HeLa Cells; Humans; Immunoprecipitation; Isoquinolines; Mass Spectrometry; Phosphorylation; Protein Binding; Proteomics; rho-Associated Kinases; Sulfonamides

Topics: 1-Methyl-3-isobutylxanthine; Adrenergic beta-Agonists; Blotting, Western; Caffeine; Cell Membrane Permeability; Cyclic AMP; Enzyme Inhibitors; Flavanones; G-Protein-Coupled Receptor Kinase 2; HCT116 Cells; HEK293 Cells; HeLa Cells; Humans; Intracellular Space; Isoproterenol; Isoquinolines; Phosphorylation; Receptors, Adrenergic, beta-2; RNA Interference; Saccharin; Signal Transduction; Sulfonamides; Taste; Tryptophan