1-methyl-3-isobutylxanthine and glutamic acid

1-methyl-3-isobutylxanthine has been researched along with glutamic acid in 22 studies

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-19901 (4.55)18.7374
1990's13 (59.09)18.2507
2000's4 (18.18)29.6817
2010's4 (18.18)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Anderson, RJ; Breckon, R; Dillingham, MA; Dixon, BS; Kaehny, MM1
Jahr, CE; Nawy, S1
Eklove, H; Webb, RA1
Braquet, P; Chabrier, PE; Demerlé-Pallardy, C; Lonchampt, MO1
Hattori, Y; Hayashi, Y; Hori, Y; Moriwaki, A1
Conejero, C; Galarreta, M; Martín del Río, R; Menéndez, N; Solís, JM1
Johnson, BG; Schoepp, DD1
Neale, JH; Saab, OH; Wroblewska, B; Wroblewski, JT1
Carreau, A; Nowicki, JP; Scatton, B; Vigé, X1
Sang, JC; Schachter, D1
Copenhagen, DR; Dixon, DB1
Kanazawa, M; Miura, M; Okada, J; Sugama, S1
Nawy, S1
Corbalán, R; Felipo, V; Kosenko, E; Llansola, M; Montoliu, C1
Anraku, M; Ichinose, M; Sawada, M1
Dunlop, J; Hediger, MA; Peng, JB; Trotti, D1
Abaffy, T; Chaudhari, N; Trubey, KR1
Genlain, M; Godaux, E; Ris, L1
Barrionuevo, G; Card, JP; Cosgrove, KE; Galván, EJ; Mauna, JC; Meriney, SD; Thiels, E1
Hou, J; Ke, H; Liu, M; Luo, HB; Xu, J; Zhao, R1
Savchenko, VL1
Barger, SW; Li, GG; McMullan, SM; Phanavanh, B1

Other Studies

22 other study(ies) available for 1-methyl-3-isobutylxanthine and glutamic acid

ArticleYear
Histidine regulation of cyclic AMP metabolism in cultured renal epithelial LLC-PK1 cells.
    The Journal of biological chemistry, 1990, Jan-15, Volume: 265, Issue:2

    Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Adenylyl Cyclases; Animals; Arginine Vasopressin; Aspartic Acid; Cells, Cultured; Colforsin; Cyclic AMP; Epithelial Cells; Epithelium; Glutamates; Glutamic Acid; Histidine; Imidazoles; Indomethacin; Kidney; Swine

1990
Suppression by glutamate of cGMP-activated conductance in retinal bipolar cells.
    Nature, 1990, Jul-19, Volume: 346, Issue:6281

    Topics: 1-Methyl-3-isobutylxanthine; Aminobutyrates; Animals; Cell Membrane; Cyclic GMP; Electric Conductivity; Glutamates; Glutamic Acid; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Photoreceptor Cells; Receptors, Glutamate; Receptors, Neurotransmitter; Retina; Second Messenger Systems; Thionucleotides; Urodela

1990
The effect of L-glutamate and related agents on adenylate cyclase in the cestode Hymenolepis diminuta.
    Canadian journal of physiology and pharmacology, 1991, Volume: 69, Issue:1

    Topics: 1-Methyl-3-isobutylxanthine; Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Cholera Toxin; Colforsin; Glutamates; Glutamic Acid; Guanylate Cyclase; Hymenolepiasis; Hymenolepis; In Vitro Techniques; Male; Rats; Rats, Inbred Strains; Serotonin; Virulence Factors, Bordetella

1991
Absence of implication of L-arginine/nitric oxide pathway on neuronal cell injury induced by L-glutamate or hypoxia.
    Biochemical and biophysical research communications, 1991, Nov-27, Volume: 181, Issue:1

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Arginine; Brain; Cell Hypoxia; Cells, Cultured; Cyclic GMP; Dizocilpine Maleate; Fetus; Glutamates; Glutamic Acid; Kainic Acid; Kinetics; N-Methylaspartate; Neuroglia; Neurons; Nitric Oxide; Nitroarginine; Nitroprusside; omega-N-Methylarginine; Quisqualic Acid; Rats

1991
Cyclic AMP levels in slices of epileptic cortex of the rat: effects of glutamate and 3-isobutyl-1-methylxanthine.
    Acta medica Okayama, 1986, Volume: 40, Issue:5

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Cerebral Cortex; Cyclic AMP; Electroencephalography; Epilepsy; Ferrous Compounds; Glutamates; Glutamic Acid; Male; Rats; Rats, Inbred Strains; Theophylline

1986
Nicotinamide adenine dinucleotides mimic adenosine inhibition on synaptic transmission by decreasing glutamate release in rat hippocampal slices.
    Neuroscience letters, 1993, Sep-03, Volume: 159, Issue:1-2

    Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Amino Acids; Animals; Electrophysiology; Female; Glutamates; Glutamic Acid; Hippocampus; In Vitro Techniques; NAD; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Synapses; Synaptic Transmission

1993
Metabotropic glutamate receptor modulation of cAMP accumulation in the neonatal rat hippocampus.
    Neuropharmacology, 1993, Volume: 32, Issue:12

    Topics: 1-Methyl-3-isobutylxanthine; Adenosine Deaminase; Animals; Animals, Newborn; Colforsin; Cyclic AMP; Cycloleucine; Female; Glutamates; Glutamic Acid; Hippocampus; Ibotenic Acid; In Vitro Techniques; Male; Neurotoxins; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Receptors, Glutamate

1993
N-acetylaspartylglutamate inhibits forskolin-stimulated cyclic AMP levels via a metabotropic glutamate receptor in cultured cerebellar granule cells.
    Journal of neurochemistry, 1993, Volume: 61, Issue:3

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Cells, Cultured; Cerebellum; Colforsin; Cyclic AMP; Cycloleucine; Dipeptides; Glutamates; Glutamic Acid; Granulocytes; Inositol Phosphates; Receptors, Glutamate

1993
Antagonism by NG-nitro-L-arginine of L-glutamate-induced neurotoxicity in cultured neonatal rat cortical neurons. Prolonged application enhances neuroprotective efficacy.
    Neuroscience, 1993, Volume: 55, Issue:4

    Topics: 1-Methyl-3-isobutylxanthine; Amino Acid Oxidoreductases; Animals; Animals, Newborn; Arginine; Cell Death; Cells, Cultured; Cerebral Cortex; Cyclic GMP; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; Neurons; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Nitroprusside; Rats; Rats, Sprague-Dawley

1993
Regional differentiation in the rat aorta for a novel signaling pathway: leucine to glutamate.
    The American journal of physiology, 1997, Volume: 273, Issue:3 Pt 2

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Aorta, Abdominal; Aorta, Thoracic; Biological Transport; Carbon Radioisotopes; Cattle; Cyclic GMP; Endothelium, Vascular; Glutamic Acid; Humans; In Vitro Techniques; Leucine; Male; Mice; Models, Cardiovascular; Organ Specificity; Rats; Rats, Sprague-Dawley; Signal Transduction

1997
Metabotropic glutamate receptor-mediated suppression of an inward rectifier current is linked via a cGMP cascade.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1997, Dec-01, Volume: 17, Issue:23

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Adenosine Triphosphate; Aminobutyrates; Animals; Atrial Natriuretic Factor; Benzoates; Cyclic GMP; Enzyme Inhibitors; Glutamic Acid; Glycine; Ictaluridae; Ion Channel Gating; Isoquinolines; Models, Neurological; Patch-Clamp Techniques; Photoreceptor Cells; Potassium Channels; Receptors, Metabotropic Glutamate; Second Messenger Systems; Thionucleotides

1997
Pharmacological properties of the CO2/H+-sensitive area in the ventral medullary surface assessed by the effects of chemical stimulation on respiration.
    Journal of the autonomic nervous system, 1998, Aug-06, Volume: 72, Issue:1

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Calcium; Carbon Dioxide; Diffusion; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Hydrogen; Male; Medulla Oblongata; Neurons; Phosphodiesterase Inhibitors; Rats; Rats, Wistar; Respiration; Stimulation, Chemical

1998
The metabotropic receptor mGluR6 may signal through G(o), but not phosphodiesterase, in retinal bipolar cells.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1999, Apr-15, Volume: 19, Issue:8

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Cyclic GMP; Glutamic Acid; In Vitro Techniques; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Receptors, Metabotropic Glutamate; Resting Phase, Cell Cycle; Retina; Signal Transduction; Thionucleotides; Urodela

1999
Role of cyclic GMP in glutamate neurotoxicity in primary cultures of cerebellar neurons.
    Neuropharmacology, 1999, Volume: 38, Issue:12

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Cell Death; Cells, Cultured; Cerebellum; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Glutamic Acid; Guanylate Cyclase; Neurons; Neuroprotective Agents; Nitric Oxide; Penicillamine; Phosphodiesterase Inhibitors; Rats

1999
Inhibition of the glutamate-induced K(+) current in identified Onchidium neurons by nitric oxide donors.
    Journal of neuroscience research, 2000, Jun-01, Volume: 60, Issue:5

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Cell Membrane; Cyclic GMP; Enzyme Inhibitors; Ganglia, Invertebrate; Glutamic Acid; Hydrazines; Mollusca; Neurons; Nitric Oxide; Nitric Oxide Donors; Nitrogen Oxides; Nitroprusside; Oxadiazoles; Phosphodiesterase Inhibitors; Potassium Channels; Quinoxalines; Vasodilator Agents

2000
Inhibition of the glutamate transporter EAAC1 expressed in Xenopus oocytes by phorbol esters.
    Brain research, 2001, Sep-28, Volume: 914, Issue:1-2

    Topics: 1-Methyl-3-isobutylxanthine; Amino Acid Transport System X-AG; Animals; Carcinogens; Carrier Proteins; Cell Membrane; Colforsin; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Enzyme Inhibitors; Excitatory Amino Acid Transporter 3; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Humans; Indoles; Maleimides; Membrane Potentials; Oocytes; Phorbols; Protein Kinase C; RNA, Complementary; Symporters; Tetradecanoylphorbol Acetate; Tritium; Tumor Cells, Cultured; Xenopus laevis

2001
Adenylyl cyclase expression and modulation of cAMP in rat taste cells.
    American journal of physiology. Cell physiology, 2003, Volume: 284, Issue:6

    Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Animals; Colforsin; Cyclic AMP; Epithelium; Glutamic Acid; Isoenzymes; Male; Phosphodiesterase Inhibitors; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Taste; Taste Buds; Transducin

2003
Involvement of hyperpolarization-activated cation channels in synaptic modulation.
    Neuroreport, 2007, Aug-06, Volume: 18, Issue:12

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic Nucleotide-Gated Cation Channels; Excitatory Postsynaptic Potentials; Glutamic Acid; Hippocampus; Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels; Neural Pathways; Neurons; Phosphodiesterase Inhibitors; Potassium; Potassium Channel Blockers; Potassium Channels; Presynaptic Terminals; Pyrimidines; Rats; Rats, Wistar; Synaptic Membranes; Synaptic Transmission

2007
Critical involvement of postsynaptic protein kinase activation in long-term potentiation at hippocampal mossy fiber synapses on CA3 interneurons.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2010, Feb-24, Volume: 30, Issue:8

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Benzophenanthridines; CA3 Region, Hippocampal; Catalytic Domain; Colforsin; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Enzyme Inhibitors; Glutamic Acid; Interneurons; Intracellular Signaling Peptides and Proteins; Long-Term Potentiation; Male; Mossy Fibers, Hippocampal; Organ Culture Techniques; Peptide Fragments; Phorbol Esters; Phosphodiesterase Inhibitors; Protein Kinase C; Protein Kinases; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Signal Transduction; Synaptic Membranes; Synaptic Transmission

2010
Structural asymmetry of phosphodiesterase-9, potential protonation of a glutamic acid, and role of the invariant glutamine.
    PloS one, 2011, Mar-31, Volume: 6, Issue:3

    Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Catalytic Domain; Crystallography, X-Ray; Enzyme Inhibitors; Glutamic Acid; Glutamine; Humans; Hydrogen Bonding; Kinetics; Molecular Dynamics Simulation; Mutation; Protein Structure, Secondary; Purinones; Structure-Activity Relationship

2011
Regulation of NADPH oxidase gene expression with PKA and cytokine IL-4 in neurons and microglia.
    Neurotoxicity research, 2013, Volume: 23, Issue:3

    Topics: 1-Methyl-3-isobutylxanthine; Amino Acid Transport System y+; Amino Acid Transport Systems, Acidic; Animals; Antibodies, Monoclonal; Arginase; Bucladesine; Cells, Cultured; Cerebral Cortex; Chitinase-3-Like Protein 1; Cyclic AMP-Dependent Protein Kinases; Enzyme Induction; Extracellular Matrix Proteins; Glutamic Acid; Glycoproteins; Interleukin-1; Interleukin-4; Membrane Glycoproteins; Microglia; NADH, NADPH Oxidoreductases; NADPH Oxidase 1; NADPH Oxidase 2; NADPH Oxidases; Nerve Tissue Proteins; Neurons; Racemases and Epimerases; Rats; Real-Time Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Time Factors

2013
Metabotropic glutamate receptors inhibit microglial glutamate release.
    ASN neuro, 2012, Aug-07, Volume: 4, Issue:5

    Topics: 1-Methyl-3-isobutylxanthine; Analysis of Variance; Animals; Animals, Newborn; Brain; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; Dioxolanes; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Excitatory Amino Acid Agents; Glutamic Acid; Lipopolysaccharides; Neuroglia; Nitrites; Purines; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; RNA, Messenger

2012