1-methyl-3-isobutylxanthine has been researched along with arachidonic acid in 49 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 18 (36.73) | 18.7374 |
| 1990's | 24 (48.98) | 18.2507 |
| 2000's | 5 (10.20) | 29.6817 |
| 2010's | 2 (4.08) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fijorek, K; Glinka, A; Mendyk, A; Polak, S; Wiśniowska, B | 1 |
| Abe, M; Hirata, M; Koga, T; Yanaga, F | 1 |
| Heap, RB; Wango, EO; Wooding, FB | 1 |
| Eidelman, O; Etcheberrigaray, R; Fox, C; Goping, G; Malden, E; Pollard, HB; Roberts, D; Yedgar, S | 1 |
| Barnett, R; Blaufox, S; Nord, EP; Ortiz, PA; Ramsammy, L; Singer, S | 1 |
| Dawson, G; McAtee, P | 2 |
| Fernandez-Gallardo, S; Garcia, C; Garcia, MC; Gijon, MA; Nieto, ML; Sanchez Crespo, M | 1 |
| Braden, G; Catella, F; Fitzgerald, DJ; FitzGerald, GA; Lawson, J; Shipp, E | 1 |
| Gil, J; Higgins, T; Rozengurt, E | 1 |
| Rapoport, RM | 1 |
| Stokes, JB | 1 |
| Hoenig, M; MacGregor, LC; Matschinsky, FM | 1 |
| Dunn, MJ; Sato, M | 1 |
| Ioannou, P; Talesnik, J | 1 |
| Chabot, MC; Chepenik, KP | 1 |
| Gennaro, DE; Godfrey, RW; Hoffstein, ST; Manzi, RM | 1 |
| Metz, SA | 1 |
| Godfrey, RW; Hoffstein, ST; Jensen, BD; Manzi, RM | 1 |
| Rodan, GA; Rodan, SB; Wesolowski, G | 1 |
| Abe, K; Hiwatari, M; Kanazawa, M; Kasai, Y; Kudo, K; Omata, K; Sato, M; Takeuchi, K; Yasujima, M; Yoshida, K | 1 |
| Collawn, JB; Kent, RS; Montgomery, ME; Whorton, AR; Young, SL | 1 |
| Al-Sinawi, LA; Burke, C; Hassan, S; Hedges, A; Mekki, QA; Moody, SG; Moti, MJ; O'Grady, J; Whittle, BJ | 1 |
| Davis, BB; Rapp, NS; Zenser, TV | 1 |
| Alonso, F; Alvarez Chiva, V; García Gil, M; Mato, JM; Sánchez Crespo, M | 1 |
| Hong, SL | 1 |
| Davis, BB; Rapp, NS; Spry, LA; Zenser, TV | 1 |
| Okajima, F; Ui, M | 1 |
| Firsov, DL; Parnova, RG | 1 |
| Malcolm, AR; Mills, LJ; Nelson, SM | 1 |
| Grinnell, F; He, Y | 1 |
| Morita, I; Murota, S; Nakahama, K | 1 |
| Hébert, RL; Kennedy, CR; Proulx, PR | 1 |
| Ahmed, MU; Hazeki, K; Hazeki, O; Katada, T; Ui, M | 1 |
| Kandel, ER; Montarolo, P; Schacher, S | 1 |
| Di Marzo, V; Piomelli, D; Schwartz, JC; Sokoloff, P; Vial, D | 1 |
| Tool, AT; Verhoeven, AJ | 1 |
| Cornejo Maciel, MF; Cymeryng, CB; Dada, LA; Finkielstein, CV; Mele, PG; Mendez, CF; Neuman, MI; Paz, C; Podestá, EJ | 1 |
| Abdel-Latif, AA; el-Mowafy, AM; Ye, Z; Yousufzai, SY | 1 |
| Colas, B; López-Ruiz, MP; Marinero, MJ; Prieto, JC | 1 |
| Eckman, DM; Hopkins, N; Keef, KD; McBride, C | 1 |
| Danon, A; Rimon, G; Samokovlisky, A | 1 |
| Ghelli, A; Mastrocola, T; Porcelli, AM; Rugolo, M | 1 |
| Bohrer, A; Hsu, FF; Ma, Z; Ramanadham, S; Turk, J; Wohltmann, M | 1 |
| Boulven, I; Harbon, S; Leiber, D; Palmier, B; Robin, P; Vacher, M | 1 |
| Bełtowski, J; Górny, D; Marciniak, A; Wójcicka, G | 1 |
| Cherng, SC; Chou, TC; Huang, WH; Lee, AR; Shiau, CY | 1 |
| Abayasekara, DR; Cheng, Z; Flint, AP; Marshall, E; Sheldrick, EL; Wathes, DC | 1 |
| Islam, MS; Jisaka, M; Khan, F; Nartey, MN; Nishimura, K; Rahman, MS; Shono, F; Syeda, PK; Yokota, K | 1 |
1 trial(s) available for 1-methyl-3-isobutylxanthine and arachidonic acid
| Article | Year |
|---|---|
A chemically stable analogue, 9 beta-methyl carbacyclin, with similar effects to epoprostenol (prostacyclin, PGI2) in man.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine Diphosphate; Adult; Arachidonic Acid; Arachidonic Acids; Bleeding Time; Blood Coagulation; Blood Platelets; Collagen; Cyclic AMP; Epoprostenol; Hemodynamics; Humans; In Vitro Techniques; Infusions, Parenteral; Male; Platelet Aggregation | 1984 |
48 other study(ies) available for 1-methyl-3-isobutylxanthine and arachidonic acid
| Article | Year |
|---|---|
Predictive model for L-type channel inhibition: multichannel block in QT prolongation risk assessment.
Topics: Artificial Intelligence; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Line; Computational Biology; Computer Simulation; Drugs, Investigational; Ether-A-Go-Go Potassium Channels; Expert Systems; Heart Rate; Humans; Models, Biological; Myocytes, Cardiac; NAV1.5 Voltage-Gated Sodium Channel; Potassium Channel Blockers; Quantitative Structure-Activity Relationship; Risk Assessment; Shaker Superfamily of Potassium Channels; Torsades de Pointes; Voltage-Gated Sodium Channel Blockers | 2012 |
Signal transduction by tumor necrosis factor alpha is mediated through a guanine nucleotide-binding protein in osteoblast-like cell line, MC3T3-E1.
Topics: 1-Methyl-3-isobutylxanthine; 3T3 Cells; Animals; Arachidonic Acid; Cyclic AMP; Dinoprostone; Dose-Response Relationship, Drug; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Inositol 1,4,5-Trisphosphate; Kinetics; Mice; Osteoblasts; Phosphates; Phospholipids; Phosphorus Radioisotopes; Receptors, Cell Surface; Receptors, Tumor Necrosis Factor; Recombinant Proteins; Signal Transduction; Tritium; Tumor Necrosis Factor-alpha | 1992 |
Regulation of steroid synthesis and metabolism in isolated binucleate cells of the placenta in sheep and goats.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Arachidonic Acid; Dinoprostone; Female; Goats; Indomethacin; Masoprocol; Placenta; Pregnancy; Pregnanediol; Progesterone; Progestins; Sheep | 1992 |
Cyclic AMP-independent secretion of mucin by SW1116 human colon carcinoma cells. Differential control by Ca2+ ionophore A23187 and arachidonic acid.
Topics: 1-Methyl-3-isobutylxanthine; Arachidonic Acid; Calcimycin; Cell Line; Colforsin; Colonic Neoplasms; Cyclic AMP; Glucuronidase; Humans; Kinetics; Mucins | 1992 |
Atrial natriuretic factor alters phospholipid metabolism in mesangial cells.
Topics: 1-Methyl-3-isobutylxanthine; Angiotensin II; Animals; Arachidonic Acid; Arachidonic Acids; Atrial Natriuretic Factor; Calcimycin; Calcium; Cells, Cultured; Cyclic GMP; Glomerular Mesangium; Inositol; Inositol Phosphates; Kinetics; Male; Muscle, Smooth; Nitroprusside; Phosphatidylinositols; Phospholipids; Rats; Rats, Inbred Strains | 1990 |
Phospholipase C activity in NCB-20 cells is inhibited by protein kinase A-mediated phosphorylation of low molecular mass GTP-binding proteins.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Arachidonic Acid; Arachidonic Acids; Bradykinin; Brain; Cell Line; Cholera Toxin; Colforsin; Cricetinae; Embryo, Mammalian; Enzyme Activation; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Hybrid Cells; Inositol Phosphates; Kinetics; Molecular Weight; Neuroblastoma; Phosphorylation; Protein Kinases; Thionucleotides; Type C Phospholipases | 1990 |
Biosynthesis of platelet-activating factor (PAF) in human polymorphonuclear leucocytes. The role of lyso-PAF disposal and free arachidonic acid.
Topics: 1-Methyl-3-isobutylxanthine; Acetyltransferases; Acyltransferases; Arachidonic Acid; Arachidonic Acids; Calcimycin; Coenzyme A Ligases; Fatty Acids; Humans; Kinetics; Leukotriene B4; Neutrophils; Platelet Activating Factor; Theophylline | 1990 |
Biosynthesis of P450 products of arachidonic acid in humans: increased formation in cardiovascular disease.
Topics: 1-Methyl-3-isobutylxanthine; 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 8,11,14-Eicosatrienoic Acid; Angina, Unstable; Angioplasty, Balloon, Coronary; Arachidonic Acid; Arachidonic Acids; Colforsin; Cyclic AMP; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme System; Female; Humans; Oxygenases; Platelet Activation; Pre-Eclampsia; Pregnancy; Prostaglandin Endoperoxides, Synthetic; Thrombin | 1991 |
Mastoparan, a novel mitogen for Swiss 3T3 cells, stimulates pertussis toxin-sensitive arachidonic acid release without inositol phosphate accumulation.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Arachidonic Acid; Arachidonic Acids; Calcium; Cell Division; Cell Line; Colforsin; Cyclic AMP; Down-Regulation; Drug Synergism; Enzyme Activation; Epidermal Growth Factor; ErbB Receptors; In Vitro Techniques; Indomethacin; Inositol Phosphates; Insulin; Intercellular Signaling Peptides and Proteins; Mice; Mitogens; Peptides; Pertussis Toxin; Phosphatidylinositols; Phosphoproteins; Protein Kinase C; Signal Transduction; Type C Phospholipases; Virulence Factors, Bordetella; Wasp Venoms | 1991 |
Inhibitory effects of cyclic AMP-elevating agents on norepinephrine-induced phosphatidylinositide hydrolysis and contraction in rat aorta.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Aorta, Thoracic; Arachidonic Acid; Arachidonic Acids; Bucladesine; Cyclic AMP; Hydrolysis; In Vitro Techniques; Indomethacin; Male; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Phosphatidylglycerols; Phosphatidylinositols; Phosphodiesterase Inhibitors; Pyrrolidinones; Rats; Rats, Inbred Strains; Rolipram | 1991 |
Modulation of vasopressin-induced water permeability of the cortical collecting tubule by endogenous and exogenous prostaglandins.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Arachidonic Acid; Arachidonic Acids; Body Water; Cell Membrane Permeability; Epithelium; Kidney Cortex; Kidney Tubules; Kinetics; Meclofenamic Acid; Naproxen; Prostaglandins; Rabbits; Vasopressins | 1985 |
In vitro exhaustion of pancreatic beta-cells.
Topics: 1-Methyl-3-isobutylxanthine; Amino Acids; Animals; Arachidonic Acid; Arachidonic Acids; Buffers; Culture Media; Glucose; In Vitro Techniques; Inositol; Insulin; Insulin Secretion; Islets of Langerhans; Keto Acids; Male; Perfusion; Rats; Rats, Inbred Strains; Time Factors | 1986 |
Osmolality, vasopressin-stimulated cAMP, and PGE2 synthesis in rat collecting tubule cells.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Animals; Arachidonic Acid; Arachidonic Acids; Arginine Vasopressin; Calcimycin; Colforsin; Cyclic AMP; Dinoprostone; Kidney Tubules; Kidney Tubules, Collecting; Osmolar Concentration; Phosphodiesterase Inhibitors; Prostaglandins E; Rats; Rats, Inbred Strains; Sodium Chloride; Stimulation, Chemical; Urea | 1986 |
Platelet antiaggregatory substances inhibit arachidonic acid induced coronary constriction.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Arachidonic Acid; Arachidonic Acids; Cardiovascular Agents; Coronary Circulation; Dipyridamole; Epoprostenol; Guinea Pigs; Heart; Hydralazine; Iloprost; In Vitro Techniques; Male; Nifedipine; Perfusion; Platelet Aggregation; Rats; Rats, Inbred Strains; Vasoconstriction | 1986 |
Cyclic AMP inhibits the release of prostaglandins and arachidonic acid from cultures of mouse embryo palate mesenchyme cells.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Arachidonic Acid; Arachidonic Acids; Bucladesine; Cells, Cultured; Connective Tissue; Cyclic AMP; Embryo, Mammalian; Female; Isoproterenol; Kinetics; Male; Mesoderm; Mice; Mice, Inbred C57BL; Palate; Pregnancy; Prostaglandins; Theophylline | 1986 |
Phospholipid and arachidonic acid metabolism in zymosan-stimulated human monocytes: modulation by cAMP.
Topics: 1-Methyl-3-isobutylxanthine; Arachidonic Acid; Arachidonic Acids; Bucladesine; Cyclic AMP; Humans; Lysosomes; Membrane Lipids; Monocytes; Phospholipases A; Phospholipids; Type C Phospholipases; Zymosan | 1987 |
Dantrolene-induced inhibition of insulin release. A mechanism independent of effects on calcium fluxes.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Arachidonic Acid; Arachidonic Acids; Calcium; Dantrolene; Fatty Acids; Hydroxymercuribenzoates; Insulin; Insulin Secretion; Male; Phospholipases A; Phospholipases A2; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate; Trifluoperazine; Type C Phospholipases | 1988 |
FMLP-induced arachidonic acid release, phospholipid metabolism, and calcium mobilization in human monocytes. Regulation by cyclic AMP.
Topics: 1-Methyl-3-isobutylxanthine; Arachidonic Acid; Arachidonic Acids; Bucladesine; Calcimycin; Calcium; Cells, Cultured; Chromatography, Thin Layer; Cyclic AMP; Cytosol; Humans; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; Phospholipids | 1988 |
Clonal differences in prostaglandin synthesis among osteosarcoma cell lines.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Arachidonic Acid; Arachidonic Acids; Calcimycin; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Clone Cells; Dinoprostone; Indomethacin; Lipid Metabolism; Osteoblasts; Osteosarcoma; Parathyroid Hormone; Phospholipids; Rabbits; Radioimmunoassay; Rats; Thrombin; Tumor Cells, Cultured | 1986 |
Rapid dephosphorylation of protein kinase C substrates by protein kinase A activators results from inhibition of diacylglycerol release.
Topics: 1-Methyl-3-isobutylxanthine; Alprostadil; Animals; Arachidonic Acid; Arachidonic Acids; Biological Transport; Bradykinin; Brain; Bucladesine; Colforsin; Cricetinae; Diglycerides; Enzyme Activation; Glycerides; Hybrid Cells; Inositol Phosphates; Kinetics; Mice; Molecular Weight; Neuroblastoma; Phosphates; Phosphatidylinositols; Phosphoproteins; Phosphorylation; Protein Kinase C; Protein Kinases; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1989 |
PGE2 synthesis in cultured renal papillary collecting tubule cells from young and aged spontaneously hypertensive rats.
Topics: 1-Methyl-3-isobutylxanthine; Aging; Animals; Arachidonic Acid; Arachidonic Acids; Blood Pressure; Calcimycin; Cells, Cultured; Cyclic AMP; Dinoprostone; Kidney Medulla; Kidney Tubules; Kidney Tubules, Collecting; Potassium; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Rats, Inbred WKY; Sodium; Thromboxane B2 | 1989 |
Arachidonic acid metabolism in cultured aortic endothelial cells. Effect of cAMP and 3-isobutyl-1-methylxanthine.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Aorta; Arachidonic Acid; Arachidonic Acids; Bradykinin; Calcimycin; Cells, Cultured; Colforsin; Cyclic AMP; Diterpenes; Endothelium; Epoprostenol; Muscle, Smooth, Vascular; Swine; Theophylline | 1985 |
Independent mechanisms for bradykinin-mediated prostaglandin E2 and cyclic GMP syntheses in rabbit renal inner medulla slices.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Bradykinin; Calcium; Cyclic GMP; Dinoprostone; In Vitro Techniques; Kidney Medulla; Prostaglandins E; Rabbits; Time Factors | 1982 |
Phospholipid turnover during phagocytosis in human polymorphonuclear leucocytes.
Topics: 1-Methyl-3-isobutylxanthine; Arachidonic Acid; Arachidonic Acids; Diacylglycerol Cholinephosphotransferase; Humans; In Vitro Techniques; Neutrophils; Phagocytosis; Phosphatidylcholines; Phospholipids; Quinacrine; Zymosan | 1982 |
Inhibition of prostacyclin synthesis in endothelial cells by methylisobutylxanthine is not mediated through elevated cAMP level.
Topics: 1-Methyl-3-isobutylxanthine; 6-Ketoprostaglandin F1 alpha; Animals; Aorta; Arachidonic Acid; Arachidonic Acids; Bucladesine; Cyclic AMP; Endothelium; Epoprostenol; Female; Humans; Kinetics; Muscle, Smooth, Vascular; Pregnancy; Swine; Theophylline; Umbilical Veins | 1983 |
Independent effects of bradykinin on adenosine 3',5'-monophosphate and prostaglandin E2 metabolism by rabbit renal medulla.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Antihypertensive Agents; Arachidonic Acid; Arachidonic Acids; Aspirin; Bradykinin; Colforsin; Cyclic AMP; Dinoprostone; Diterpenes; In Vitro Techniques; Kidney Medulla; Kinetics; Prostaglandins E; Rabbits | 1984 |
ADP-ribosylation of the specific membrane protein by islet-activating protein, pertussis toxin, associated with inhibition of a chemotactic peptide-induced arachidonate release in neutrophils. A possible role of the toxin substrate in Ca2+-mobilizing bios
Topics: 1-Methyl-3-isobutylxanthine; Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Animals; Arachidonic Acid; Arachidonic Acids; Bacterial Toxins; Calcimycin; Calcium; Chemotaxis, Leukocyte; Cholera Toxin; Cyclic AMP; Dose-Response Relationship, Drug; Guinea Pigs; Male; Membrane Proteins; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Nucleoside Diphosphate Sugars; Pertussis Toxin; Superoxides; Virulence Factors, Bordetella | 1984 |
The effect of arachidonic acid on the hydroosmotic action of vasopressin in frog urinary bladder.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Arachidonic Acid; Arginine Vasopressin; Colforsin; Cyclic AMP; Drug Interactions; Fatty Acids, Nonesterified; In Vitro Techniques; Kinetics; Rana temporaria; Urinary Bladder | 1994 |
Effects of selected anti-tumor-promoting chemicals on metabolic cooperation between Chinese hamster V79 cells.
Topics: 1-Methyl-3-isobutylxanthine; Acetates; Acetic Acid; Acetophenones; Animals; Anticarcinogenic Agents; Arachidonic Acid; Caffeine; Cell Communication; Cells, Cultured; Cricetinae; Cricetulus; Gap Junctions; Lipoxygenase Inhibitors; Mutation; Phosphodiesterase Inhibitors; Phospholipases A; Protease Inhibitors; Pyrazoles; Tosylphenylalanyl Chloromethyl Ketone | 1994 |
Stress relaxation of fibroblasts activates a cyclic AMP signaling pathway.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Arachidonic Acid; Calcimycin; Calcium; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cytochalasin D; Egtazic Acid; Extracellular Matrix; Fibroblasts; Humans; Indomethacin; Magnesium; Signal Transduction; Stress, Mechanical | 1994 |
Effects of endogenously produced arachidonic acid metabolites on rat mesangial cell proliferation.
Topics: 1-Methyl-3-isobutylxanthine; 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Animals; Arachidonic Acid; Benzeneacetamides; Bucladesine; Carbazoles; Cell Division; Cells, Cultured; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dinoprost; Dinoprostone; DNA Replication; Flavanones; Flavonoids; Glomerular Mesangium; Hydroxamic Acids; Hydroxyeicosatetraenoic Acids; Indoles; Indomethacin; Lipoxygenase Inhibitors; Male; Platelet-Derived Growth Factor; Pyrroles; Rats; Rats, Sprague-Dawley; Umbelliferones | 1994 |
Regulation of bradykinin-stimulated phospholipase C and arachidonic acid release by protein kinase A in MDCK-D1 cells.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Arachidonic Acid; Arginine Vasopressin; Bradykinin; Calcimycin; Cell Line; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Diglycerides; Dogs; Enzyme Activation; Enzyme Inhibitors; Estrenes; Inositol Phosphates; Ionophores; Isoquinolines; Kidney; Pyrrolidinones; Sulfonamides; Type C Phospholipases | 1995 |
Cyclic AMP-increasing agents interfere with chemoattractant-induced respiratory burst in neutrophils as a result of the inhibition of phosphatidylinositol 3-kinase rather than receptor-operated Ca2+ influx.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Arachidonic Acid; Biological Transport, Active; Calcium; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Guinea Pigs; In Vitro Techniques; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphatidylinositol 3-Kinases; Phosphotransferases (Alcohol Group Acceptor); Receptors, Formyl Peptide; Receptors, Immunologic; Receptors, Peptide; Respiratory Burst; Signal Transduction; Superoxides; Tetradecanoylphorbol Acetate | 1995 |
cAMP and arachidonic acid simulate long-term structural and functional changes produced by neurotransmitters in Aplysia sensory neurons.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Aplysia; Arachidonic Acid; Cells, Cultured; Cyclic AMP; Electric Stimulation; Evoked Potentials; Ganglia; Neurons, Afferent; Neurotransmitter Agents; Second Messenger Systems; Synapses | 1993 |
Selection of alternative G-mediated signaling pathways at the dopamine D2 receptor by protein kinase C.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Alkaloids; Animals; Arachidonic Acid; Calcimycin; Calcium; CHO Cells; Colforsin; Cricetinae; Cyclic AMP; Diglycerides; Diterpenes; Dopamine D2 Receptor Antagonists; Ergolines; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Kinetics; Protein Kinase C; Quinpirole; Raclopride; Receptors, Dopamine D2; Recombinant Proteins; Salicylamides; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate; Transfection | 1993 |
Inhibition of the production of platelet activating factor and of leukotriene B4 in activated neutrophils by nimesulide due to an elevation of intracellular cyclic adenosine monophosphate.
Topics: 1-Methyl-3-isobutylxanthine; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cytochalasin B; Enzyme Inhibitors; Humans; In Vitro Techniques; Isoquinolines; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphodiesterase Inhibitors; Platelet Activating Factor; Protein Kinase Inhibitors; Sulfonamides; Zymosan | 1995 |
Site of action of proteinases in the activation of steroidogenesis in rat adrenal gland.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Adrenocorticotropic Hormone; Animals; Arachidonic Acid; Corticosterone; Cyclic AMP; Endopeptidases; Hydroxycholesterols; In Vitro Techniques; Kinetics; Male; Phenanthrolines; Phenylmethylsulfonyl Fluoride; Pregnenolone; Progesterone; Protease Inhibitors; Rats; Rats, Wistar; Zona Fasciculata | 1996 |
Prostaglandins mediate the stimulatory effects of endothelin-1 on cyclic adenosine monophosphate accumulation in ciliary smooth muscle isolated from bovine, cat, and other mammalian species.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Animals; Arachidonic Acid; Cats; Cattle; Ciliary Body; Cyclic AMP; Cyclooxygenase Inhibitors; Dinoprostone; Dogs; Dose-Response Relationship, Drug; Endothelin Receptor Antagonists; Endothelins; Humans; Indomethacin; Inositol 1,4,5-Trisphosphate; Isometric Contraction; Masoprocol; Muscle, Smooth; Phosphodiesterase Inhibitors; Phospholipases A; Phospholipases A2; Prostaglandins; Receptors, Endothelin; Time Factors | 1996 |
Different sites of action of arachidonic acid on steroidogenesis in rat Leydig cells.
Topics: 1-Methyl-3-isobutylxanthine; Adenylate Cyclase Toxin; Animals; Arachidonic Acid; Bucladesine; Colforsin; Cyclic AMP; GTP-Binding Proteins; Humans; In Vitro Techniques; Leydig Cells; Luteinizing Hormone; Male; Pertussis Toxin; Placental Lactogen; Rats; Rats, Sprague-Dawley; Receptors, LH; Testosterone; Virulence Factors, Bordetella | 1996 |
Endothelium-dependent relaxation and hyperpolarization in guinea-pig coronary artery: role of epoxyeicosatrienoic acid.
Topics: 1-Methyl-3-isobutylxanthine; 4-Aminopyridine; 8,11,14-Eicosatrienoic Acid; Acetylcholine; Animals; Arachidonic Acid; Arteries; Biological Factors; Coronary Vessels; Cytochrome P-450 Enzyme Inhibitors; Endothelium, Vascular; Enzyme Inhibitors; Guinea Pigs; In Vitro Techniques; Male; Membrane Potentials; Muscle Relaxation; Potassium Channel Blockers; Vasodilator Agents | 1998 |
Differential regulation of cyclooxygenase isoenzymes by cAMP-elevating agents.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Aorta; Arachidonic Acid; Blotting, Western; Bucladesine; Cattle; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Drug Interactions; Endothelium, Vascular; Enzyme Inhibitors; Epoprostenol; In Vitro Techniques; Isoenzymes; Lipopolysaccharides; Okadaic Acid; Prostaglandin-Endoperoxide Synthases; Proteins; Thionucleotides | 1999 |
Arachidonic acid release by ionomycin and phorbol ester is similar in C127 epithelial cells expressing wild-type or mutated (delta F508) cystic fibrosis transmembrane conductance regulator.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Arachidonic Acid; Calcium; Cell Line; Colforsin; Cyclic AMP; Cystic Fibrosis Transmembrane Conductance Regulator; Epithelial Cells; Immunoblotting; Ionomycin; Ionophores; Ions; Mice; Mutation; Phorbol Esters; Phospholipases A; Phospholipases A2; Spectrometry, Fluorescence; Time Factors; Transfection | 1999 |
Studies of insulin secretory responses and of arachidonic acid incorporation into phospholipids of stably transfected insulinoma cells that overexpress group VIA phospholipase A2 (iPLA2beta ) indicate a signaling rather than a housekeeping role for iPLA2b
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Animals; Arachidonic Acid; Colforsin; Enzyme Inhibitors; Glucose; Group VI Phospholipases A2; Humans; Insulin; Insulin Secretion; Insulinoma; Kinetics; Mice; Naphthalenes; Pancreatic Neoplasms; Phosphatidylcholines; Phospholipases A; Phospholipases A2; Phospholipids; Pyrones; Rats; Recombinant Proteins; Signal Transduction; Spectrometry, Mass, Electrospray Ionization; Substrate Specificity; Transfection; Tumor Cells, Cultured | 2001 |
Platelet-derived growth factor stimulates phospholipase C-gamma 1, extracellular signal-regulated kinase, and arachidonic acid release in rat myometrial cells: contribution to cyclic 3',5'-adenosine monophosphate production and effect on cell proliferatio
Topics: 1-Methyl-3-isobutylxanthine; Animals; Arachidonic Acid; Arachidonic Acids; Becaplermin; Cell Division; Cells, Cultured; Colforsin; Cyclic AMP; Cyclooxygenase Inhibitors; Drug Synergism; Enzyme Activation; Epoprostenol; Female; GTP-Binding Protein alpha Subunits, Gs; Indomethacin; Inositol Phosphates; Isoenzymes; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Myometrium; Phospholipases A; Phosphotyrosine; Platelet-Derived Growth Factor; Proto-Oncogene Proteins c-sis; Rats; Rats, Wistar; Type C Phospholipases | 2001 |
The opposite effects of cyclic AMP-protein kinase a signal transduction pathway on renal cortical and medullary Na+,K+-ATPase activity.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Alkaloids; Animals; Arachidonic Acid; Bucladesine; Carbazoles; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cytochrome P-450 Enzyme System; Enzyme Activation; Enzyme Inhibitors; Hydroxyeicosatetraenoic Acids; Indoles; Kidney Cortex; Kidney Medulla; Male; Okadaic Acid; Phosphodiesterase Inhibitors; Pyrroles; Rats; Rats, Wistar; Signal Transduction; Sodium-Potassium-Exchanging ATPase | 2002 |
Mechanisms of antiplatelet activity of PC-09, a newly synthesized pyridazinone derivative.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Adenosine Triphosphate; Alprostadil; Animals; Arachidonic Acid; Blood Platelets; Calcium; Collagen; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Imidazoles; Indomethacin; Naphthalenes; Phosphodiesterase Inhibitors; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Pyridazines; Rabbits; Thrombin; Thromboxane A2; Thromboxane-A Synthase | 2006 |
Control of cyclic AMP concentration in bovine endometrial stromal cells by arachidonic acid.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclase Inhibitors; Animals; Arachidonic Acid; Cattle; Cells, Cultured; Colforsin; Cyclic AMP; Cyclooxygenase 2; Depression, Chemical; Dinoprostone; Endometrium; Female; Indoles; Maleimides; Paracrine Communication; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Protein Kinase C; Stromal Cells; Tetradecanoylphorbol Acetate | 2007 |
Pretreatment of cultured preadipocytes with arachidonic acid during the differentiation phase without a cAMP-elevating agent enhances fat storage after the maturation phase.
Topics: 1-Methyl-3-isobutylxanthine; 3T3-L1 Cells; 6-Ketoprostaglandin F1 alpha; Acetates; Adipocytes; Adipogenesis; Animals; Arachidonic Acid; Cell Differentiation; Cells, Cultured; Cyclic AMP; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Dinoprost; Dinoprostone; Gene Expression Regulation; Humans; Hydroxyprostaglandin Dehydrogenases; Membrane Proteins; Mesenchymal Stem Cells; Mice; Prostaglandin-E Synthases; Pyrazines; Receptors, Prostaglandin; Receptors, Prostaglandin E, EP4 Subtype; Signal Transduction; Triglycerides | 2016 |