1-methyl-3-isobutylxanthine has been researched along with adenosine in 193 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 113 (58.55) | 18.7374 |
| 1990's | 59 (30.57) | 18.2507 |
| 2000's | 13 (6.74) | 29.6817 |
| 2010's | 7 (3.63) | 24.3611 |
| 2020's | 1 (0.52) | 2.80 |
| Authors | Studies |
|---|---|
| Browne, RG; Howard, HR; Koe, BK; Lebel, LA; Sarges, R; Seymour, PA | 1 |
| Daly, JW | 1 |
| Borea, PA; Dalpiaz, A; Gilli, G; Gilli, P; Scatturin, A; Varani, K | 1 |
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Butcher, RW; Kelly, LA; Wu, C | 1 |
| Goodman, HM; Honeyman, TW; Levy, LK | 1 |
| Edstrom, JP; Kirkpatrick, JR; Kostopoulos, GK; Phillis, JW | 1 |
| Daly, JW; Smellie, FW; Wells, JN | 1 |
| Bortot, L; Cutrufo, C; Giachetti, A; Manzini, S | 1 |
| Richter, J | 1 |
| Ito, H; Kajinuma, H; Makino, H; Suzuki, T; Yamazaki, M; Yoshida, S | 1 |
| Cho, WK; Kim, K; Lee, CC; Lee, DK; Shim, C | 1 |
| Mita, M | 1 |
| Hall, AK | 1 |
| Prince, DA; Stevens, CF | 1 |
| Kather, H | 1 |
| Howell, RE; Kinnier, WJ; Muehsam, WT | 1 |
| Ishimura, Y; Kizaki, H; Suzuki, K; Tadakuma, T | 1 |
| Alonso, MJ; Ibañez, C; Marín, J; Reviriego, J | 1 |
| Mohell, N; Nedergaard, J; Unelius, L | 1 |
| Alexander, B; Mathie, RT | 1 |
| Bilodeau, S; Sirard, MA | 1 |
| Fukami, S; Iijima, Y; Kaneko, M; Kiuchi, Y; Mishima, H; Yamazaki, M; Yasumoto, T; Yokoyama, T | 1 |
| Greenfield, LJ; Hackett, JT; Linden, J | 1 |
| Chabardès, D; Montégut, M; Siaume-Perez, S; Zhou, Y | 1 |
| Hashimoto, N; Kanatsuka, A; Makino, H; Yamazaki, M; Yoshida, S | 1 |
| Abdel-Aleem, S; Badr, M; Frangakis, C | 1 |
| Canonico, PL; Catania, MV; Nicoletti, F; Rampello, L; Sortino, MA | 1 |
| Gunther, GR; Herring, MB | 1 |
| Ali, H; Beaven, MA; Daly, JW; Müller, CE | 1 |
| Nicholson, D; Sawynok, J; White, TD | 1 |
| Levine, JD; Taiwo, YO | 1 |
| Gaal, L; Illes, P; Schudt, C | 1 |
| Cai, SD; Qiu, YG; Wei, XD; You, SX | 1 |
| Churchill, PC; Wu, PH | 1 |
| Kitos, TE; Michaelis, ML; Mooney, T | 1 |
| Gerber, JG; Nies, AS; Payne, NA | 1 |
| Ooi, SO; Wong, EH | 1 |
| Barker, JA; Duckworth, WC; Heckemeyer, CM; Solomon, SS | 1 |
| Donner, K; Hemilä, S | 1 |
| Anand-Srivastava, MB; Cantin, M; Gutkowska, J | 1 |
| Dzierzanowski, D; McCarthy, L; Schimmel, RJ | 1 |
| Dhillon, GS; Honnor, RC; Londos, C | 1 |
| Besharse, JC; Iuvone, PM | 1 |
| Coffin, VL; Spealman, RD | 1 |
| Anand-Srivastava, MB | 1 |
| de Gregorio, A; Marin, J; Salaices, M | 2 |
| Berger, C; Meyer, W; Scholz, H; Starbatty, J | 1 |
| Barraco, RA; DeLong, RE; Phillis, JW; Washington, DO | 1 |
| Church, MK; Hughes, PJ; Vardey, CJ | 1 |
| Butcher, RW; Clark, RB; Proll, MA | 1 |
| Harden, TK; Hughes, AR | 1 |
| Hoskins, DD; Vijayaraghavan, S | 1 |
| Blazynski, C; Ferrendelli, JA; Geary, KM; Kinscherf, DA | 1 |
| Birch, RE; Polmar, SH | 1 |
| Shima, S | 1 |
| Dolphin, AC; Forda, SR; Scott, RH | 1 |
| Stinnakre, J; Van Renterghem, C | 1 |
| Kelly, E; Nahorski, SR | 1 |
| DeLander, GE; Hopkins, CJ | 1 |
| Fox, IH; John, D | 1 |
| Dalaker, K; Prydz, H | 1 |
| Crowley, JJ; Cusack, BJ; Nielson, CP; Vestal, RE | 1 |
| Dar, MS; Wooles, WR | 1 |
| Brown, SJ; Richardson, PJ | 1 |
| Holtzman, SG | 1 |
| Dodd, PR; Johnston, GA; Watson, WE | 1 |
| Aitken, RJ; Irvine, S; Mattei, A | 1 |
| Arend, LJ; Smith, WL; Sonnenburg, WK; Spielman, WS | 1 |
| Schmeichel, CJ; Thomas, LL | 1 |
| Leung, E; Woodcock, EA | 1 |
| Behrman, HR; Parmer, TG; Preston, SL | 1 |
| Narahashi, T; Tsunoo, A | 1 |
| Browning, ET; Etgen, AM | 1 |
| Blazynski, C | 1 |
| Belloni, FL; Gerritsen, ME; Liang, BC | 1 |
| Paes de Carvalho, R; Ventura, AL | 1 |
| Brady, MJ; Nairn, AC; Nichols, RA; Palfrey, HC | 1 |
| Beek, D; Kenakin, TP | 1 |
| Berry-Kravis, E; Dawson, G; Derechin, V; Kazmierczak, BI | 1 |
| Böhm, M; Brückner, R; Neumann, J; Nose, M; Schmitz, W; Scholz, H | 1 |
| Ribeiro, JA; Sebastião, AM | 1 |
| Madelian, V; Shain, W; Silliman, S | 1 |
| Keery, RJ; Lumley, P | 1 |
| Aronstam, RS; Catravas, JD; Legrand, AB; Narayanan, TK; Ryan, US | 1 |
| de Mazancourt, P; Giot, J; Giudicelli, Y; Lacasa, D | 1 |
| Adams, RN; Johe, KK; Michaelis, ML; Moghadam, B | 1 |
| Arend, LJ; Gusovsky, F; Handler, JS; Rhim, JS; Spielman, WS | 1 |
| Jackman, SA; Nicholson, CD; Wilke, R | 1 |
| Bornslaeger, EA; Daniel, SA; Downs, SM; Eppig, JJ; Hoppe, PC | 1 |
| Frauman, AG; Moses, AC; Tramontano, D; Veneziani, BM | 1 |
| Alberts, P | 1 |
| Mersmann, HJ | 1 |
| de Mello, FG; Paes de Carvalho, R | 2 |
| Renit-Soria, J; Stinnakre, J; Van Renterghem, C | 1 |
| d'Almeida, MS; Lautt, WW; Legare, DJ | 1 |
| Diaz, C; Gill, JM; Schiffman, SS | 1 |
| Kenno, KA; Krug, CH; Kryski, A; Severson, DL | 1 |
| Dobson, JG; Frohloff, N; LaMonica, DA | 1 |
| Hollen, CE; Linden, J; Patel, A | 1 |
| Hertting, G; Jackisch, R; Kasakov, L; Strittmatter, H | 1 |
| Halprin, KM; Levine, V; Taylor, JR | 1 |
| Link, HB; Rösen, P; Rösen, R; Schrör, K | 1 |
| Schimmel, RJ | 1 |
| Epstein, PM; Hersh, EM; Ross, CP; Strada, SJ; Thompson, WJ | 1 |
| Klaus, W; Link, HB; Rösen, P; Rösen, R; Schrör, K | 1 |
| Kohler, G; Peck, WA | 1 |
| Fishman, RF; Novogrodsky, A; Rubin, AL; Stenzel, KH | 1 |
| Oleshansky, MA | 1 |
| Gagnon, G; Regoli, D; Rioux, F | 1 |
| Anand-Srivastava, MB; Johnson, RA | 1 |
| Cooper, DM; Londos, C; Rodbell, M | 1 |
| Hollins, C; Lloyd, H; Stone, TW | 1 |
| Kagey-Sobotka, A; Lichtenstein, LM; Marone, G | 1 |
| Cooper, DM; Jagus, R | 1 |
| Anand-Srivastava, MB; Johnson, RA; Olaus, TH | 1 |
| Linden, J; Sperelakis, N; Vogel, S | 1 |
| Jacquemin, C; Lambert, B | 1 |
| Gardner, JD; Jackson, MJ; Korman, LY; Lemp, GF | 1 |
| Lichtenstein, LM; MacGlashan, DW; Newball, HH; Peters, SP; Schleimer, RP; Schulman, ES | 1 |
| Florine, DL; Scott, RE; Yun, K | 1 |
| Anand-Srivastava, MB; Cantin, M | 1 |
| Honeyman, TW; McMahon, KK; Schimmel, RJ | 1 |
| Galloway, MP; Roth, RH | 1 |
| Collins, GG; Motley, SJ | 1 |
| Hewlett, EL; Myers, GA; Olansky, L; Pohl, SL | 1 |
| Dickinson, ES; Goldman, SJ; Slakey, LL | 1 |
| Adachi, K; Comerford, M; Halprin, KM; Levine, V; Taylor, JR; Woodyard, C | 1 |
| Bukowiecki, LJ; Szillat, D | 1 |
| Budohoski, L; Challiss, RA; McManus, B; Newsholme, EA | 1 |
| Annau, Z; Bruns, RF; Daly, JW; Katims, JJ; Snyder, SH | 1 |
| McCarthy, L; Schimmel, RJ | 1 |
| Matsui, H; Yamamoto, C | 1 |
| Plagemann, PG; Wohlhueter, RM | 1 |
| Baukal, A; Catt, KJ; Darbon, JM; Knecht, M; Ranta, T | 1 |
| Sklar, P; Snyder, SH | 1 |
| Azuma, H; Ishikawa, M; Takashima, Y; Yamakado, T | 1 |
| Altman, HJ; Barraco, RA; Coffin, VL; Phillis, JW; Taylor, JA | 1 |
| Dobbins, JW; Forrest, JN; Laurenson, JP | 1 |
| Conti, M; Monaco, L; Toscano, MV | 1 |
| Conejero, C; Galarreta, M; Martín del Río, R; Menéndez, N; Solís, JM | 1 |
| Bertaccini, G; Coruzzi, G; Poli, E; Pozzoli, C | 1 |
| Herzer, WA; Jackson, EK; Mi, Z; Zhang, Y | 1 |
| Hirayoshi, K; Nagata, K; Okuma, M; Yamaguchi, M | 1 |
| Assmann, SM; Li, W; Luan, S; Schreiber, SL | 1 |
| Craig, CG; Temple, SD; White, TD | 1 |
| Borea, PA; Dalpiaz, A; Gilli, G; Guerra, L; Varani, K | 1 |
| Dong, XW; Feldman, JL | 1 |
| Jackson, EK; Mi, Z | 3 |
| Hume, JR; Levesque, PC | 1 |
| Daly, JW; Jacobson, KA; Nikodijević, O | 1 |
| Challiss, RA; Morgan, AJ; Murray, KJ | 1 |
| Altiok, N; Fredholm, BB | 1 |
| Fujii, W; Namba, T; Suga, H; Takaki, M | 1 |
| Akaike, N; Kawa, K; Uneyama, H; Yamashita, Y | 1 |
| Ailhaud, G; Børglum, JD; Darimont, C; Gaillard, D; Négrel, R; Richelsen, B; Vassaux, G | 1 |
| Cazin, L; Le Foll, F; Mei, YA; Vaudry, H | 1 |
| Dubey, RK; Gillespie, DG; Jackson, EK; Mi, Z | 3 |
| Monteiro, EC; Monteiro, TC; Silva e Sousa, MA; Vera-Cruz, P | 1 |
| Dobson, JG; Ethier, MF | 1 |
| Cordoba, P; Sutter-Dub, MT | 1 |
| Dukhanin, AS; Gubaeva, FR; Sergeev, PV | 1 |
| Brundege, JM; Diao, L; Dunwiddie, TV; Proctor, WR | 1 |
| Chen, Y; D'Angelo, G; Michel, JB; Pueyo, ME | 1 |
| Ball, SG; Balmforth, AJ; Fearon, IM; Mikala, G; Palmer, AC; Peers, C | 1 |
| Bobbin, RP; Chen, C | 1 |
| Boyadjieva, N; Sarkar, DK | 1 |
| Habuchi, Y; Morikawa, J; Nishio, M; Tanaka, H; Yamamoto, T | 1 |
| Hohl, CM | 1 |
| Brock, JA; Hardy, TA | 1 |
| Starodub, AM; Wood, JD | 1 |
| Frühbeck, G; Gómez-Ambrosi, J; Salvador, J | 1 |
| Dubey, RK; Jackson, EK; Mi, Z; Zhu, C | 1 |
| Brummer, T; Huber, M; Minguet, S; Reth, M; Rosenkranz, L; Schamel, WW | 1 |
| Andrisani, OM; Bilodeau, ML; Ji, M; Paris, M | 1 |
| Dubey, RK; Jackson, EK; Mi, Z | 1 |
| Calin-Jageman, R; Clemens, S; Katz, PS; Sakurai, A | 1 |
| Ravid, K; Smith, BD; Xu, Y | 1 |
| Batuca, JR; Conde, SV; Gonzalez, C; Monteiro, EC; Obeso, A | 1 |
| Catt, KJ; Frattarelli, JL; Krsmanovic, LZ | 1 |
| Dubey, RK; Exo, JL; Gillespie, DG; Jackson, EK; Jackson, TC; Kochanek, PM; Ren, J; Verrier, JD | 1 |
| Foote, CC; Gordon, JS; Rodrigues, AS; Ruta, JD; Schroeder, JA | 1 |
| Gillespie, DG; Jackson, EK | 1 |
| Bianciotti, LG; Burdet, J; Davio, C; Diez, F; Franchi, A; Gervasi, MG; Osycka-Salut, C; Perez-Martinez, S | 1 |
| Bansal, R; Gillespie, DG; Goebbels, S; Jackson, EK; Jackson, TC; Janesko-Feldman, K; Kochanek, PM; Nave, KA; Verrier, JD | 1 |
| Bertoldo, MJ; Bustamante, S; Gilchrist, RB; Kanakkaparambil, R; Lavea, CF; Richani, D; Riepsamen, AH | 1 |
| Dimitriadis, E; Ebrahimi, SM; Fazaeli, H; Jannatifar, R; Naserpoor, L; Nejatbakhsh, R; Piroozmanesh, H | 1 |
2 review(s) available for 1-methyl-3-isobutylxanthine and adenosine
| Article | Year |
|---|---|
Adenosine receptors: targets for future drugs.
Topics: Adenosine; Adenosine Triphosphate; Animals; Humans; Ligands; Receptors, Cell Surface; Receptors, Purinergic; Structure-Activity Relationship; Xanthines | 1982 |
Adenosine receptor interactions and anxiolytics.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Animals; Anti-Anxiety Agents; Benzodiazepines; Caffeine; Diazepam; Humans; Motor Activity; Receptors, Cell Surface; Receptors, GABA-A; Receptors, Purinergic | 1983 |
191 other study(ies) available for 1-methyl-3-isobutylxanthine and adenosine
| Article | Year |
|---|---|
4-Amino[1,2,4]triazolo[4,3-a]quinoxalines. A novel class of potent adenosine receptor antagonists and potential rapid-onset antidepressants.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Antidepressive Agents; Behavior, Animal; Caffeine; Cats; Cell Membrane; Cerebral Cortex; Chemical Phenomena; Chemistry; Corpus Striatum; Male; Molecular Structure; Motor Activity; Purinergic Antagonists; Quinoxalines; Rats; Receptors, Purinergic; Sleep; Structure-Activity Relationship; Triazoles | 1990 |
Binding thermodynamics as a tool to investigate the mechanisms of drug-receptor interactions: thermodynamics of cytoplasmic steroid/nuclear receptors in comparison with membrane receptors.
Topics: Estradiol; Female; Humans; In Vitro Techniques; Male; Metribolone; Pregnenediones; Prostate; Receptors, Androgen; Receptors, Cell Surface; Receptors, Estrogen; Receptors, Progesterone; Receptors, Steroid; Thermodynamics; Uterus | 2005 |
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
The escape of cyclic AMP from human diploid fibroblasts: general properties.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Blood; Cells, Cultured; Culture Media; Cyclic AMP; Fibroblasts; Humans; Hydrogen-Ion Concentration; Isoproterenol; Phosphodiesterase Inhibitors; Prostaglandins E; Temperature | 1978 |
Independent regulation of phosphorylase and lipolysis in adipose tissue.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adipose Tissue; Animals; Bucladesine; Cyclic AMP; Enzyme Activation; Lipid Metabolism; Male; Phosphorylase a; Phosphorylases; Prostaglandins E; Rats; Serotonin | 1979 |
Effects of adenosine and adenine nucleotides on synaptic transmission in the cerebral cortex.
Topics: 1-Methyl-3-isobutylxanthine; Action Potentials; Adenine Nucleotides; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Monophosphate; Animals; Brain; Caffeine; Cerebral Cortex; Male; Neural Inhibition; Neurons; Rats; Synapses; Synaptic Transmission; Theophylline | 1979 |
1-Isoamyl-3-isobutylxanthine: a remarkably potent agent for the potentiation of norepinephrine, histamine, and adenosine-elicited accumulations of cyclic AMP in brain slices.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Animals; Brain; Cyclic AMP; Drug Synergism; Guinea Pigs; Histamine; In Vitro Techniques; Male; Norepinephrine; Phosphodiesterase Inhibitors; Theophylline; Xanthines | 1979 |
Differential effects of various xanthines on pentylenetetrazole-induced seizures in rats: an EEG and behavioural study.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Behavior, Animal; Caffeine; Electroencephalography; Male; Parasympatholytics; Pentylenetetrazole; Rats; Rats, Wistar; Seizures; Theophylline; Xanthines | 1992 |
Effect of adenosine analogues and cAMP-raising agents on TNF-, GM-CSF-, and chemotactic peptide-induced degranulation in single adherent neutrophils.
Topics: 1-Methyl-3-isobutylxanthine; 2-Chloroadenosine; Adenosine; Blood Proteins; Bucladesine; Cell Adhesion; Cell Degranulation; Chemotactic Factors; Colforsin; Cyclic AMP; Cytochalasin B; Exocytosis; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1992 |
The role of insulin-sensitive phosphodiesterase in insulin action.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Adenosine; Adipose Tissue; Animals; Cyclic AMP; Dose-Response Relationship, Drug; Glycerol; In Vitro Techniques; Insulin; Phenylisopropyladenosine; Rats; Rats, Inbred Strains; Tritium | 1992 |
Inhibitory effect of purines in meiotic maturation of denuded mouse oocytes.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Allopurinol; Animals; Cells, Cultured; Econazole; Female; Hypoxanthines; Meiosis; Mice; Mice, Inbred ICR; Microinjections; Oocytes; Purines | 1992 |
Involvement of cyclic adenosine 3',5'-monophosphate in methylation during 1-methyladenine production by starfish ovarian follicle cells.
Topics: 1-Methyl-3-isobutylxanthine; Adenine; Adenosine; Animals; Concanavalin A; Cyclic AMP; Female; Methionine; Methionine Adenosyltransferase; Methylation; Ovarian Follicle; Starfish; Trypsin | 1992 |
Influence of cyclic AMP and serum factors upon expression of a retinoid-responsive gene in neuroblastoma cells.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Amino Acid Sequence; Animals; Blood Physiological Phenomena; Bucladesine; Butyrates; Butyric Acid; Cell Differentiation; Cholera Toxin; Cyclic AMP; DNA; Gene Expression Regulation, Neoplastic; Incidence; Molecular Sequence Data; Neuroblastoma; Rats; Retinoids; Second Messenger Systems; Thymosin; Tumor Cells, Cultured | 1992 |
Adenosine decreases neurotransmitter release at central synapses.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Animals; Dose-Response Relationship, Drug; Electric Conductivity; Hippocampus; In Vitro Techniques; Membrane Potentials; Rats; Synapses; Synaptic Transmission | 1992 |
Beta-adrenergic stimulation of adenine nucleotide catabolism and purine release in human adipocytes.
Topics: 1-Methyl-3-isobutylxanthine; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenine Nucleotides; Adenosine; Adenosine Triphosphate; Adipose Tissue; Cells, Cultured; Cyclic AMP; Female; Humans; Hypoxanthine; Hypoxanthines; Inosine; Isoproterenol; Kinetics; Lipolysis; Propranolol; Receptors, Adrenergic, beta | 1990 |
Mechanism for the emetic side effect of xanthine bronchodilators.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Animals; Bronchodilator Agents; Dose-Response Relationship, Drug; Ferrets; Male; Nausea; Phosphodiesterase Inhibitors; Theophylline; Vomiting; Xanthines | 1990 |
Adenosine receptor-mediated accumulation of cyclic AMP-induced T-lymphocyte death through internucleosomal DNA cleavage.
Topics: 1-Methyl-3-isobutylxanthine; 2-Chloroadenosine; 8-Bromo Cyclic Adenosine Monophosphate; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Bucladesine; Cell Survival; Cells, Cultured; Cholera Toxin; Colforsin; Cyclic AMP; Kinetics; Male; Mice; Mice, Inbred BALB C; Phenylisopropyladenosine; Receptors, Purinergic; T-Lymphocytes | 1990 |
Action of adenosine and characterization of adenosine receptors in human placental vasculature.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Blood Vessels; Bucladesine; Calcium Radioisotopes; Cell Membrane Permeability; Cyclic AMP; Dinoprost; Female; Humans; In Vitro Techniques; Muscle Contraction; Muscle, Smooth, Vascular; Phenylisopropyladenosine; Placenta; Potassium; Pregnancy; Receptors, Purinergic | 1990 |
Cold acclimation induces desensitization to adenosine in brown fat cells without changing receptor binding.
Topics: 1-Methyl-3-isobutylxanthine; 2-Chloroadenosine; Acclimatization; Adenosine; Adenosine Deaminase; Adipose Tissue, Brown; Animals; Cell Membrane; Cells, Cultured; Cold Temperature; Cricetinae; Edetic Acid; Kinetics; Magnesium; Male; Mesocricetus; Norepinephrine; Oxygen Consumption; Phenylisopropyladenosine; Receptors, Purinergic | 1990 |
The role of adenosine in the hyperaemic response of the hepatic artery to portal vein occlusion (the 'buffer response').
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Animals; Dogs; Dose-Response Relationship, Drug; Female; Hepatic Artery; Hyperemia; In Vitro Techniques; Male; Portal Vein; Theophylline | 1990 |
Effects of granulosa cell co-culture on in-vitro meiotic resumption of bovine oocytes.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Animals; Cattle; Cell Adhesion; Cells, Cultured; Female; Granulosa Cells; Heparin; Meiosis; Oocytes | 1990 |
Griseolic acid, a cAMP phosphodiesterase inhibitor, and its ester: increase in cellular cAMP levels and reduction of intraocular pressure.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Adenosine; Animals; Cattle; Cell Line; Cyclic AMP; Esters; Fibroblasts; Intraocular Pressure; Mice; Molecular Structure; Rabbits; Structure-Activity Relationship | 1990 |
Xenopus oocyte K+ current. III. Phorbol esters and pH regulate current at gap junctions.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Colforsin; Cyclic AMP; Female; Follicle Stimulating Hormone; Hydrogen-Ion Concentration; Intercellular Junctions; Isoproterenol; Kinetics; Mathematics; Models, Biological; Oocytes; Phorbol 12,13-Dibutyrate; Potassium Channels; Xenopus laevis | 1990 |
Two mechanisms of inhibition by prostaglandin E2 of hormone-dependent cell cAMP in the rat collecting tubule.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenosine; Animals; Arginine Vasopressin; Colforsin; Cyclic AMP; Dinoprostone; Indomethacin; Isoproterenol; Kidney Tubules, Collecting; Male; Phenylisopropyladenosine; Rats; Rats, Inbred Strains; Signal Transduction; Xanthines | 1990 |
Effects of the new phosphodiesterase inhibitor griseolic acid on insulin release in rat pancreatic islets.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Adenosine; Animals; Calcium; Calcium Radioisotopes; Cyclic AMP; In Vitro Techniques; Insulin; Islets of Langerhans; Male; Rats; Rats, Inbred Strains | 1990 |
Stimulation of fatty acid oxidation in myocytes by phosphodiesterase inhibitors and adenosine analogues.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Amrinone; Animals; Cells, Cultured; Dipyridamole; Enoximone; Heart; Imidazoles; Milrinone; Myocardium; Oxidation-Reduction; Palmitic Acid; Palmitic Acids; Phosphodiesterase Inhibitors; Purinones; Pyridazines; Pyridones; Rats | 1991 |
Adenosine deaminase increases release of excitatory amino acids through a mechanism independent of adenosine depletion.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adenosine Deaminase; Adenosine-5'-(N-ethylcarboxamide); Amino Acids; Animals; Aspartic Acid; Calcium; Calcium Radioisotopes; Cells, Cultured; Cerebellum; Female; Hydrolysis; Phosphatidylinositols; Rats; Rats, Inbred Strains; Theophylline | 1991 |
Inhibition of neutrophil superoxide production by adenosine released from vascular endothelial cells.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adenosine Deaminase; Adenosine-5'-(N-ethylcarboxamide); Cells, Cultured; Endothelium, Vascular; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pentostatin; Superoxides; Umbilical Veins | 1991 |
Methylxanthines block antigen-induced responses in RBL-2H3 cells independently of adenosine receptors or cyclic AMP: evidence for inhibition of antigen binding to IgE.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Antigens; Cyclic AMP; Dinitrophenols; Immunoglobulin E; Purinergic Antagonists; Rats; Receptors, Purinergic; Serum Albumin, Bovine; Structure-Activity Relationship; Tumor Cells, Cultured; Type C Phospholipases; Vasodilator Agents; Xanthines | 1991 |
Forskolin and phosphodiesterase inhibitors release adenosine but inhibit morphine-evoked release of adenosine from spinal cord synaptosomes.
Topics: 1-Methyl-3-isobutylxanthine; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; 5'-Nucleotidase; Adenosine; Animals; Colforsin; Cyclic AMP; In Vitro Techniques; Morphine; Phosphodiesterase Inhibitors; Pyrrolidinones; Rats; Rolipram; Spinal Cord; Synaptosomes | 1991 |
Further confirmation of the role of adenyl cyclase and of cAMP-dependent protein kinase in primary afferent hyperalgesia.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adenylyl Cyclases; Animals; Colforsin; Cyclic AMP; Dinoprostone; Epoprostenol; Hyperalgesia; Male; Phosphorylation; Protein Kinases; Pyrrolidinones; Rats; Rats, Inbred Strains; Rolipram; Second Messenger Systems; Sensory Thresholds; Thionucleotides | 1991 |
Effects of phosphodiesterase inhibition on the excitability of hippocampal pyramidal neurons in vitro.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Animals; Electric Stimulation; Evoked Potentials; Hippocampus; In Vitro Techniques; Isoproterenol; Male; Neurons; Phosphodiesterase Inhibitors; Pyramidal Tracts; Pyridazines; Pyrrolidinones; Rats; Rats, Inbred Strains; Rolipram | 1991 |
Effects of adenosine and its derivatives on cultured myocardial cells and detection of adenosine receptors in rat.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Binding, Competitive; Cells, Cultured; Depression, Chemical; Female; Male; Myocardium; Phenylisopropyladenosine; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Purinergic | 1991 |
2-Chloro-[3H]-adenosine binding in isolated rat kidney membranes.
Topics: 1-Methyl-3-isobutylxanthine; 2-Chloroadenosine; Adenosine; Animals; Binding, Competitive; In Vitro Techniques; Kidney; Rats; Receptors, Cell Surface; Receptors, Purinergic; Theophylline | 1985 |
Characteristics of adenosine binding sites in atrial sarcolemmal membranes.
Topics: 1-Methyl-3-isobutylxanthine; 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Binding Sites; Binding, Competitive; Cattle; Endopeptidases; Heart Atria; Myocardium; Sarcolemma; Subcellular Fractions; Theophylline; Time Factors | 1985 |
Adenosine receptors on canine parietal cells modulate gastric acid secretion to histamine.
Topics: 1-Methyl-3-isobutylxanthine; 2-Chloroadenosine; Adenosine; Animals; Dogs; Dose-Response Relationship, Drug; Female; Gastric Acid; Histamine; In Vitro Techniques; Male; Parietal Cells, Gastric; Phenylisopropyladenosine; Prostaglandins; Receptors, Cell Surface; Receptors, Purinergic; Theophylline | 1985 |
Methylxanthine and non-xanthine phosphodiesterase inhibitors. Their effects on adenosine uptake and the low Km cyclic AMP phosphodiesterase in intact rat adipocyte.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Adenosine; Adipose Tissue; Animals; Dipyridamole; Guanosine Triphosphate; In Vitro Techniques; Insulin; Kinetics; Lipolysis; Male; Papaverine; Rats; Rats, Inbred Strains; Xanthines | 1985 |
Hormonal control of lipolysis in perifused adipocytes from diabetic rats.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adipose Tissue; Animals; Diabetes Mellitus, Experimental; Epinephrine; Fatty Acids, Nonesterified; Insulin; Insulin Resistance; Lipolysis; Perfusion; Rats; Time Factors | 1985 |
Rhodopsin phosphorylation inhibited by adenosine in frog rods: lack of effects on excitation.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Animals; Darkness; Kinetics; Perfusion; Phosphorylation; Photic Stimulation; Photoreceptor Cells; Rana temporaria; Retinal Pigments; Rhodopsin | 1985 |
Adenosine-sensitive adenylate cyclase in rat anterior pituitary.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adenylyl Cyclases; Animals; Cations, Divalent; Deoxyadenosines; Female; Guanine Nucleotides; In Vitro Techniques; Phenylisopropyladenosine; Pituitary Gland, Anterior; Rats; Rats, Inbred Strains; Theophylline | 1985 |
Effects of pertussis toxin treatment on metabolism in hamster brown adipocytes.
Topics: 1-Methyl-3-isobutylxanthine; 2-Chloroadenosine; Adenosine; Adenosine Deaminase; Adenylate Cyclase Toxin; Adenylyl Cyclases; Adipose Tissue, Brown; Animals; Cricetinae; Drug Synergism; Isoproterenol; Lipolysis; Male; Mesocricetus; NAD; Oxygen Consumption; Pertussis Toxin; Phenylephrine; Virulence Factors, Bordetella | 1985 |
cAMP-dependent protein kinase and lipolysis in rat adipocytes. I. Cell preparation, manipulation, and predictability in behavior.
Topics: 1-Methyl-3-isobutylxanthine; Adenine; Adenosine; Adenosine Deaminase; Adipose Tissue; Animals; Isoproterenol; Kinetics; Lipolysis; Male; Phenylisopropyladenosine; Protein Kinases; Rats; Rats, Inbred Strains; Seasons; Starvation | 1985 |
Cyclic AMP stimulates serotonin N-acetyltransferase activity in Xenopus retina in vitro.
Topics: 1-Methyl-3-isobutylxanthine; Acetyltransferases; Adenosine; Animals; Arylamine N-Acetyltransferase; Bucladesine; Calcium; Circadian Rhythm; Colforsin; Cyclic AMP; Darkness; Fishes; Guinea Pigs; In Vitro Techniques; Light; Melatonin; Retina; Tyrosine 3-Monooxygenase; Xenopus laevis | 1986 |
Modulation of the behavioral effects of chlordiazepoxide by methylxanthines and analogs of adenosine in squirrel monkeys.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Caffeine; Chlordiazepoxide; Conditioning, Psychological; Male; Phenylisopropyladenosine; Receptors, Cell Surface; Receptors, Purinergic; Saimiri; Theobromine; Theophylline; Xanthines | 1985 |
Regulation of adenylate cyclase by adenosine and other agonists in rat myocardial sarcolemma.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Catecholamines; Cations, Divalent; Enzyme Activation; Glucagon; Guanine Nucleotides; Myocardium; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Purinergic; Sarcolemma | 1985 |
Study of vasodilator effects of papaverine, adenosine and related drugs in isolated cat cerebral arteries.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Animals; Bucladesine; Cats; Cerebral Arteries; Cyclic AMP; Drug Interactions; In Vitro Techniques; Muscle, Smooth, Vascular; Papaverine; Vasoconstriction; Vasodilation; Vasodilator Agents | 1985 |
Effects of the benzimidazole derivatives pimobendan and 2-(4-hydroxy-phenyl)-5-(5-methyl-3-oxo-4,5-dihydro-2H-6- pyridazinyl) benzimidazole . HCl on phosphodiesterase activity and force of contraction in guinea-pig hearts.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adenylyl Cyclases; Animals; Carbachol; Cardiotonic Agents; Female; Guinea Pigs; Heart Atria; Histamine; In Vitro Techniques; Isoproterenol; Male; Myocardial Contraction; Myocardium; Ouabain; Papillary Muscles; Phenylisopropyladenosine; Phosphodiesterase Inhibitors; Pyridazines | 1985 |
Behavioral characteristics of centrally administered adenosine analogs.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adenosine Deaminase Inhibitors; Animals; Caffeine; Dilazep; Dipyridamole; Injections, Intraventricular; Male; Mice; Mice, Inbred ICR; Motor Activity | 1986 |
Studies on the receptor mediating cyclic AMP-independent enhancement by adenosine of IgE-dependent mediator release from rat mast cells.
Topics: 1-Methyl-3-isobutylxanthine; Adenine; Adenine Nucleotides; Adenosine; Animals; Cyclic AMP; Dose-Response Relationship, Drug; Immunoglobulin E; In Vitro Techniques; Male; Mast Cells; Phenylisopropyladenosine; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Purinergic; Serotonin; Tachyphylaxis; Theophylline; Time Factors; Tubercidin | 1986 |
A1 and A2 adenosine receptors regulate adenylate cyclase in cultured human lung fibroblasts.
Topics: 1-Methyl-3-isobutylxanthine; Adenine; Adenosine; Adenylate Cyclase Toxin; Adenylyl Cyclases; Cell Line; Cyclic AMP; Fibroblasts; Humans; Lung; Receptors, Cell Surface; Receptors, Purinergic; Theophylline; Virulence Factors, Bordetella | 1986 |
Effect of some vasodilators on cat femoral arteries.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Animals; Cats; Cyclic AMP; Femoral Artery; In Vitro Techniques; Muscle, Smooth, Vascular; Papaverine; Vasodilation; Vasodilator Agents | 1986 |
Adenosine and muscarinic cholinergic receptors attenuate cyclic AMP accumulation by different mechanisms in 1321N1 astrocytoma cells.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adenosine Deaminase; Adenylate Cyclase Toxin; Adenylyl Cyclases; Astrocytoma; Cell Line; Cyclic AMP; GTP-Binding Proteins; Humans; Pertussis Toxin; Phenylisopropyladenosine; Receptors, Cell Surface; Receptors, Muscarinic; Receptors, Purinergic; Virulence Factors, Bordetella | 1986 |
Regulation of bovine sperm motility and cyclic adenosine 3',5'-monophosphate by adenosine and its analogues.
Topics: 1-Methyl-3-isobutylxanthine; 2-Chloroadenosine; Adenosine; Animals; Bicarbonates; Cattle; Cyclic AMP; Dibucaine; Male; Sperm Motility; Spermatozoa; Structure-Activity Relationship; Theophylline | 1986 |
Adenosine-mediated regulation of cyclic AMP levels in isolated incubated retinas.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Animals; Cyclic AMP; Dopamine; Guinea Pigs; Mice; Norepinephrine; Papaverine; Rabbits; Rats; Retina; Species Specificity | 1986 |
Adenosine induced immunosuppression: the role of the adenosine receptor--adenylate cyclase interaction in the alteration of T-lymphocyte surface phenotype and immunoregulatory function.
Topics: 1-Methyl-3-isobutylxanthine; 2-Chloroadenosine; Adenosine; Adenylyl Cyclases; Adult; Antibodies, Monoclonal; Antigens, Surface; B-Lymphocytes; Cell Differentiation; Humans; Immune Tolerance; Isoproterenol; Kinetics; Receptors, Cell Surface; Receptors, Purinergic; T-Lymphocytes; Theophylline | 1986 |
Inhibition by adenosine of ACTH-stimulated adenylate cyclase and steroidogenesis in the adrenal cortex.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adenylyl Cyclases; Adrenal Cortex; Adrenocorticotropic Hormone; Animals; Bucladesine; Deoxyadenosines; Dideoxyadenosine; Male; Phenylisopropyladenosine; Rats; Sodium Fluoride; Steroids | 1986 |
Calcium-dependent currents in cultured rat dorsal root ganglion neurones are inhibited by an adenosine analogue.
Topics: 1-Methyl-3-isobutylxanthine; 2-Chloroadenosine; Action Potentials; Adenosine; Adenylyl Cyclases; Animals; Baclofen; Calcium; Cells, Cultured; Depression, Chemical; Ganglia, Spinal; Ion Channels; Neurons; Potassium; Rats; Tetraethylammonium; Tetraethylammonium Compounds; Theophylline | 1986 |
Cyclic adenosine monophosphate, calcium, acetylcholine and the current induced by adenosine in the Xenopus oocyte.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Acetylcholine; Adenosine; Animals; Calcimycin; Calcium; Colforsin; Cyclic AMP; Egtazic Acid; Electrophysiology; Female; Isoproterenol; Oocytes; Potassium; Progesterone; Xenopus laevis | 1986 |
Specific inhibition of dopamine D-1-mediated cyclic AMP formation by dopamine D-2, muscarinic cholinergic, and opiate receptor stimulation in rat striatal slices.
Topics: 1-Methyl-3-isobutylxanthine; 2-Chloroadenosine; 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Adenosine; Alprostadil; Animals; Benzazepines; Carbachol; Cholera Toxin; Corpus Striatum; Cyclic AMP; Isoproterenol; Morphine; Phenethylamines; Rats; Receptors, Cholinergic; Receptors, Dopamine; Receptors, Muscarinic; Receptors, Opioid; Vasoactive Intestinal Peptide | 1986 |
Spinal adenosine modulates descending antinociceptive pathways stimulated by morphine.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Analgesia; Animals; Caffeine; Hyperalgesia; Injections, Intraventricular; Injections, Spinal; Male; Mice; Morphine; Naloxone; Nociceptors; Spinal Cord; Theophylline; Xanthines | 1986 |
Characteristics of high affinity and low affinity adenosine binding sites in human cerebral cortex.
Topics: 1-Methyl-3-isobutylxanthine; 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Cell Membrane; Cerebral Cortex; Humans; Kinetics; Phenylisopropyladenosine; Receptors, Purinergic; Theophylline | 1986 |
Effect of some drugs on thromboplastin activity in mouse trophoblast cells in vitro and in vivo.
Topics: 1-Methyl-3-isobutylxanthine; Adenine; Adenosine; Animals; Calcium Channel Blockers; Dinoprostone; Felodipine; Female; Gallic Acid; Methylation; Mice; Monensin; Nifedipine; Nitrendipine; Pregnancy; Prostaglandins E; Thromboplastin; Trophoblasts; Tubercidin; Verapamil | 1986 |
Therapeutic concentrations of theophylline and enprofylline potentiate catecholamine effects and inhibit leukocyte activation.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adult; Bucladesine; Calcimycin; Calcium; Catecholamines; Dinoprostone; Dose-Response Relationship, Drug; Drug Synergism; Humans; Isoproterenol; Middle Aged; Neutrophils; Prostaglandins E; Theophylline; Xanthines | 1986 |
Effect of chronically administered methylxanthines on ethanol-induced motor incoordination in mice.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Animals; Brain; Caffeine; Drug Synergism; Ethanol; Kinetics; Male; Mice; Motor Activity; Receptors, Purinergic; Theophylline; Xanthines | 1986 |
ATP release from affinity-purified rat cholinergic nerve terminals.
Topics: 1-Methyl-3-isobutylxanthine; 2-Chloroadenosine; Acetylcholine; Adenosine; Adenosine Triphosphate; Animals; Cholinergic Fibers; Chromatography, High Pressure Liquid; Potassium Chloride; Rats; Sheep; Theophylline; Veratridine | 1987 |
Discriminative stimulus properties of caffeine in the rat: noradrenergic mediation.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adrenergic alpha-Antagonists; Animals; Apomorphine; Avoidance Learning; Caffeine; Clonidine; Diazepam; Discrimination Learning; Male; Norepinephrine; Pentobarbital; Picrotoxin; Rats; Rats, Inbred Strains; Theobromine; Theophylline | 1986 |
Adenosine receptors in post-mortem human cerebral cortex and the effect of carbamazepine.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Binding, Competitive; Carbamazepine; Cerebral Cortex; Humans; In Vitro Techniques; Kinetics; Phenylisopropyladenosine; Postmortem Changes; Receptors, Purinergic; Software; Theophylline | 1986 |
Paradoxical stimulation of human sperm motility by 2-deoxyadenosine.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Caffeine; Calcimycin; Colforsin; Cyclic AMP; Deoxyadenosines; Freezing; Humans; Male; Sperm Motility; Spermatozoa; Stimulation, Chemical | 1986 |
A1 and A2 adenosine receptors in rabbit cortical collecting tubule cells. Modulation of hormone-stimulated cAMP.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adenylate Cyclase Toxin; Animals; Arginine Vasopressin; Cyclic AMP; Isoproterenol; Kidney Cortex; Kidney Tubules; Kidney Tubules, Collecting; Pertussis Toxin; Phenylisopropyladenosine; Rabbits; Receptors, Purinergic; Virulence Factors, Bordetella; Xanthines | 1987 |
Methylxanthine bronchodilators potentiate multiple human neutrophil functions.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adenosine Deaminase; Aminophylline; Bronchodilator Agents; Cell Aggregation; Chemotaxis, Leukocyte; Dose-Response Relationship, Drug; Humans; In Vitro Techniques; Lysosomes; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphodiesterase Inhibitors; Receptors, Purinergic; Superoxides; Theophylline; Xanthines | 1987 |
Effect of temperature on atrial and ventricular adenosine A1 receptors of the guinea pig.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adenylyl Cyclase Inhibitors; Animals; Guinea Pigs; Heart Atria; Heart Ventricles; In Vitro Techniques; Male; Myocardium; Receptors, Purinergic; Temperature; Theophylline | 1986 |
Adenosine reverses calcium-dependent inhibition of follicle-stimulating hormone action and induction of maturation in cumulus-enclosed rat oocytes.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Animals; Bucladesine; Calcimycin; Calcium; Cyclic AMP; Ethers; Female; Follicle Stimulating Hormone; Ionomycin; Oocytes; Rats; Rats, Inbred Strains | 1987 |
Cyclic nucleotide potentiation of muscarinic responses in neuroblastoma cells.
Topics: 1-Methyl-3-isobutylxanthine; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Acetylcholine; Adenine; Adenosine; Animals; Bucladesine; Cell Line; Cyclic AMP; Cyclic GMP; Dopamine; Membrane Potentials; Neurons; Receptors, Muscarinic | 1987 |
Calcium dependence of vasoactive intestinal peptide-stimulated cyclic AMP accumulation in rat hippocampal slices.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Animals; Calcium; Calmodulin; Colforsin; Cyclic AMP; Female; Hippocampus; Magnesium; Norepinephrine; Phosphoric Diester Hydrolases; Rats; Rats, Inbred Strains; Vasoactive Intestinal Peptide | 1987 |
Adenosine A1 receptor-mediated inhibition of adenylate cyclase in rabbit retina.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adenylyl Cyclases; Animals; Autoradiography; Guanosine Triphosphate; Phenylisopropyladenosine; Rabbits; Receptors, Purinergic; Retina | 1987 |
Effects of alkylxanthines and calcium antagonists on adenosine uptake by cultured rabbit coronary microvascular endothelium.
Topics: 1-Methyl-3-isobutylxanthine; Adenine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Calcium Channel Blockers; Cells, Cultured; Coronary Vessels; Dipyridamole; Endothelium; Ethanol; Isoproterenol; Male; Microcirculation; Rabbits; Theophylline; Trifluoperazine; Xanthines | 1987 |
Development of adenosine-dependent cyclic AMP accumulation in the avian optic tectum.
Topics: 1-Methyl-3-isobutylxanthine; 2-Chloroadenosine; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenosine; Adenosine Deaminase; Animals; Chick Embryo; Cyclic AMP; Dipyridamole; Proteins; Superior Colliculi | 1987 |
Nerve growth factor treatment or cAMP elevation reduces Ca2+/calmodulin-dependent protein kinase III activity in PC12 cells.
Topics: 1-Methyl-3-isobutylxanthine; 2-Chloroadenosine; Adenosine; Adrenal Gland Neoplasms; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Colforsin; Cyclic AMP; Cytosol; Elongation Factor 2 Kinase; Epidermal Growth Factor; Kinetics; Nerve Growth Factors; Pheochromocytoma; Phosphorylation; Protein Kinases | 1987 |
Measurement of antagonist affinity for purine receptors of drugs producing concomitant phosphodiesterase blockade: the use of pharmacologic resultant analysis.
Topics: 1-Methyl-3-isobutylxanthine; 2-Chloroadenosine; Adenosine; Animals; Dose-Response Relationship, Drug; Guinea Pigs; Heart; In Vitro Techniques; Male; Phosphodiesterase Inhibitors; Purines; Rats; Rats, Inbred Strains; Receptors, Purinergic; Regression Analysis; Theophylline; Vas Deferens | 1987 |
Neuromodulator-mediated phosphorylation of specific proteins in a neurotumor hybrid cell line (NCB-20).
Topics: 1-Methyl-3-isobutylxanthine; 2-Chloroadenosine; Adenosine; Alprostadil; Animals; Brain; Calcimycin; Colforsin; Cricetinae; Cyclic AMP; Electrophoresis, Polyacrylamide Gel; Embryo, Mammalian; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Hybrid Cells; Immunoassay; Mice; Nerve Tissue Proteins; Neuroblastoma; Neurotransmitter Agents; Phosphoproteins; Phosphorylation; Protein Kinases; Serotonin; Tumor Cells, Cultured; Tyrosine 3-Monooxygenase | 1988 |
Adenosine inhibits the positive inotropic effect of 3-isobutyl-1-methylxanthine in papillary muscles without effect on cyclic AMP or cyclic GMP.
Topics: 1-Methyl-3-isobutylxanthine; Action Potentials; Adenosine; Animals; Calcium; Cyclic AMP; Cyclic GMP; Guinea Pigs; Heart; In Vitro Techniques; Myocardial Contraction; Myocardium; Papillary Muscles; Phenylisopropyladenosine; Theophylline | 1988 |
On the adenosine receptor and adenosine inactivation at the rat diaphragm neuromuscular junction.
Topics: 1-Methyl-3-isobutylxanthine; 2-Chloroadenosine; Adenosine; Animals; Diaphragm; Evoked Potentials; Female; In Vitro Techniques; Male; Motor Endplate; Muscle Contraction; Neuromuscular Junction; Rats; Rats, Inbred Strains; Receptors, Purinergic; Temperature; Theophylline | 1988 |
Adenosine stimulates cAMP-mediated taurine release from LRM55 glial cells.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Animals; Astrocytes; Cell Line; Cyclic AMP; Isoproterenol; Propranolol; Rats; Taurine | 1988 |
AH6809, a prostaglandin DP-receptor blocking drug on human platelets.
Topics: 1-Methyl-3-isobutylxanthine; 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine; Adenosine Diphosphate; Adenosine-5'-(N-ethylcarboxamide); Dinoprost; Epoprostenol; Humans; Hydantoins; In Vitro Techniques; Male; Platelet Activating Factor; Platelet Aggregation; Prostaglandin D2; Prostaglandin Endoperoxides, Synthetic; Receptors, Immunologic; Receptors, Prostaglandin; Xanthenes; Xanthones | 1988 |
Modulation of adenylate cyclase activity in cultured bovine pulmonary arterial endothelial cells. Effects of adenosine and derivatives.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adenylyl Cyclases; Animals; Cattle; Cells, Cultured; Colforsin; Endothelium, Vascular; Guanylyl Imidodiphosphate; Pulmonary Artery; Receptors, Adrenergic, beta; Receptors, Purinergic; Structure-Activity Relationship | 1989 |
Role of adenosine 3',5'-monophosphate and the Ri-receptor Gi-coupled adenylate cyclase inhibitory pathway in the mechanism whereby adrenalectomy increases the adenosine antilipolytic effect in rat fat cells.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Adenosine; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Adipose Tissue; Adrenalectomy; Animals; Bucladesine; Cyclic AMP; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Guanylyl Imidodiphosphate; Isoproterenol; Lipolysis; Male; Manganese; Niacin; Phenylisopropyladenosine; Rats; Rats, Inbred Strains; Receptors, Purinergic; Thionucleotides | 1989 |
Studies on the ionic mechanism for the neuromodulatory actions of adenosine in the brain.
Topics: 1-Methyl-3-isobutylxanthine; 2-Chloroadenosine; Adenosine; Animals; Calcium; Male; Neurotransmitter Agents; Potassium; Potassium Channels; Rats; Rats, Inbred Strains; Synaptic Membranes; Synaptosomes; Thiocyanates; Valinomycin; Veratridine | 1988 |
Adenosine-sensitive phosphoinositide turnover in a newly established renal cell line.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Calcium; Cell Line; Cyclic AMP; Cyclic GMP; Cytosol; Epithelium; Kidney Tubules, Collecting; Membrane Potentials; Pertussis Toxin; Phosphatidylinositols; Rabbits; Virulence Factors, Bordetella | 1989 |
The ability of denbufylline to inhibit cyclic nucleotide phosphodiesterase and its affinity for adenosine receptors and the adenosine re-uptake site.
Topics: 1-Methyl-3-isobutylxanthine; 2',3'-Cyclic-Nucleotide Phosphodiesterases; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Cerebral Cortex; In Vitro Techniques; Kinetics; Male; Myocardium; Phenylisopropyladenosine; Rats; Rats, Inbred Strains; Receptors, Purinergic; Theophylline; Thioinosine; Xanthines | 1989 |
Maintenance of meiotic arrest in mouse oocytes by purines: modulation of cAMP levels and cAMP phosphodiesterase activity.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Adenosine; Animals; Cells, Cultured; Cyclic AMP; Female; Follicle Stimulating Hormone; Hypoxanthine; Hypoxanthines; Meiosis; Mice; Mice, Inbred C57BL; Microinjections; Oocytes; Purines | 1989 |
Adenosine has divergent effects on deoxyribonucleic acid synthesis in FRTL5 cells: inhibition of thyrotropin-stimulated and potentiation of insulin-like growth factor-I-stimulated thymidine incorporation.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adenosine Deaminase; Animals; Bucladesine; Cell Line; Cholera Toxin; Colforsin; DNA; DNA Replication; Drug Synergism; Insulin-Like Growth Factor I; Kinetics; Somatomedins; Thymidine; Thyroid Gland; Thyrotropin | 1989 |
Effects of N6,2'-O-dibutyryladenosine 3',5'-cyclic monophosphate, adenosine, and of oxotremorine and 3-isobutyl-1-methylxanthine on the electrically evoked [3H]acetylcholine secretion in the guinea-pig ileum myenteric plexus.
Topics: 1-Methyl-3-isobutylxanthine; Acetylcholine; Adenosine; Animals; Bucladesine; Electric Stimulation; Guinea Pigs; Ileum; Myenteric Plexus; Oxotremorine; Physostigmine; Receptors, Muscarinic; Theophylline | 1989 |
Inhibition of porcine adipose tissue lipogenesis by beta-adrenergic agonists.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adipose Tissue; Adrenergic beta-Agonists; Animals; Caffeine; Drug Interactions; Epinephrine; Isoproterenol; Lipids; Male; Propranolol; Swine; Theophylline | 1989 |
Expression of A1 adenosine receptors modulating dopamine-dependent cyclic AMP accumulation in the chick embryo retina.
Topics: 1-Methyl-3-isobutylxanthine; 2-Chloroadenosine; Adenosine; Animals; Apomorphine; Chick Embryo; Cyclic AMP; Dopamine; Dose-Response Relationship, Drug; Receptors, Cell Surface; Receptors, Purinergic; Retina | 1985 |
beta-Adrenergic induced K+ current in Xenopus oocytes: role of cAMP, inhibition by muscarinic agents.
Topics: 1-Methyl-3-isobutylxanthine; 4-Aminopyridine; 8-Bromo Cyclic Adenosine Monophosphate; Acetylcholine; Adenosine; Aminobenzoates; Aminopyridines; Animals; Atropine; Calcimycin; Colforsin; Cyclic AMP; Diterpenes; Female; Isoproterenol; Oocytes; Phosphodiesterase Inhibitors; Potassium; Receptors, Adrenergic, beta; Tetraethylammonium Compounds; Xenopus laevis | 1985 |
Adenosine as putative regulator of hepatic arterial flow (the buffer response).
Topics: 1-Methyl-3-isobutylxanthine; 2-Chloroadenosine; Adenosine; Animals; Blood Pressure; Cats; Dipyridamole; Hepatic Artery; Liver Circulation; Portal System; Rheology; Time Factors; Vasodilation | 1985 |
Methyl xanthines enhance taste: evidence for modulation of taste by adenosine receptor.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adult; Animals; Caffeine; Female; Humans; In Vitro Techniques; Male; Neurons; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Purinergic; Taste; Theobromine; Theophylline; Xanthines | 1985 |
Regulation of rates of lipolysis in isolated myocardial cells from rat heart.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Animals; Calcium; Calcium Chloride; Cells, Cultured; Epinephrine; Fatty Acids, Nonesterified; Glycerol; Isoproterenol; Lipase; Lipolysis; Myocardium; Norepinephrine; Phenylisopropyladenosine; Propranolol; Rats | 1985 |
Adenosine inhibition of catecholamine-stimulated cardiac membrane adenylate cyclase.
Topics: 1-Methyl-3-isobutylxanthine; 2-Chloroadenosine; Adenosine; Adenosine Deaminase; Adenylyl Cyclase Inhibitors; Animals; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Guinea Pigs; Isoproterenol; Male; Myocardium; Phenylisopropyladenosine; Rats; Rats, Inbred Strains; Sodium Fluoride | 1985 |
The mechanism by which adenosine and cholinergic agents reduce contractility in rat myocardium. Correlation with cyclic adenosine monophosphate and receptor densities.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adenylyl Cyclases; Animals; Cyclic AMP; Heart Atria; Heart Ventricles; Male; Methacholine Chloride; Methacholine Compounds; Myocardial Contraction; Parasympathomimetics; Phenylisopropyladenosine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Receptors, Cell Surface; Receptors, Muscarinic; Receptors, Purinergic | 1985 |
Endogenous adenosine as a modulator of hippocampal acetylcholine release.
Topics: 1-Methyl-3-isobutylxanthine; Acetylcholine; Adenosine; Animals; Caudate Nucleus; Dipyridamole; Electric Stimulation; Hippocampus; In Vitro Techniques; Pyrrolidinones; Rabbits; Receptors, Cell Surface; Receptors, Purinergic; Rolipram; Theophylline | 1984 |
Inhibitors of epidermal cell DNA synthesis in surviving pig skin in vitro.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Animals; Cell Division; Cyclic AMP; DNA; Epidermal Cells; Epidermis; Epinephrine; Histamine; Hydroxyurea; In Vitro Techniques; Swine; Theophylline | 1980 |
Physiological and biochemical parameters of prostacyclin action on the heart and the coronary vasculature.
Topics: 1-Methyl-3-isobutylxanthine; Adenine Nucleotides; Adenosine; Animals; Blood Pressure; Cattle; Coronary Vessels; Cyclic AMP; Epoprostenol; Heart; Heart Rate; In Vitro Techniques; Organophosphorus Compounds; Oxygen Consumption; Prostaglandins; Rats; Vascular Resistance | 1980 |
Interactions between catecholamines, methyl xanthines and adenosine in regulation of cyclic AMP accumulation in hamster adipocytes.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adenosine Deaminase; Adipose Tissue; Animals; Caffeine; Catecholamines; Cricetinae; Cyclic AMP; Epinephrine; Isoproterenol; Mesocricetus; Norepinephrine; Phentolamine; Theophylline | 1980 |
Activation of human lymphocyte high affinity cyclic AMP phosphodiesterase by culture with 1-methyl-3-isobutylxanthine.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; 3',5'-Cyclic-GMP Phosphodiesterases; Adenosine; Adult; Azides; Cyclic AMP; Cyclic GMP; Cycloheximide; Dactinomycin; Enzyme Activation; Humans; Kinetics; Lymphocytes; Theophylline | 1980 |
Prostacyclin-induced coronary vasodilation. Interactions with adenosine, cyclic AMP and energy charge in the rat heart in vitro.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Animals; Coronary Vessels; Cyclic AMP; Dose-Response Relationship, Drug; Drug Interactions; Energy Metabolism; Epoprostenol; Female; Heart; In Vitro Techniques; Myocardium; Phosphates; Prostaglandins; Rats; Vascular Resistance; Vasodilator Agents | 1980 |
Hormonal and nonhormonal desensitization in isolated bone cells.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Adenosine; Animals; Bone and Bones; Butyrates; Cells, Cultured; Cyclic AMP; Female; Fetus; Parathyroid Hormone; Pregnancy; Prostaglandins E; Rats; Sodium Fluoride | 1980 |
Selective suppression of blastogenesis induced by different mitogens: effect of noncyclic adenosine-containing compounds.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adenosine Triphosphate; Adult; Cyclic AMP; Humans; Lymphocyte Activation; Mitogens | 1980 |
Inhibition by purine compounds of cyclic GMP-stimulated cyclic AMP phosphodiesterase activity from a particulate fraction of rat striatum.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Adenosine; Animals; Corpus Striatum; Cyclic GMP; Dose-Response Relationship, Drug; Hypoxanthines; Inosine; Male; Purines; Rats; Theophylline | 1980 |
Studies on the mechanism of action of various vasodilators.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Animals; Calcium; Cyclic AMP; In Vitro Techniques; Isoproterenol; Muscle, Smooth, Vascular; Nitroglycerin; Papaverine; Rabbits; Vasodilator Agents; Verapamil | 1980 |
Regulation of adenosine-sensitive adenylate cyclase from rat brain striatum.
Topics: 1-Methyl-3-isobutylxanthine; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenosine; Adenylyl Cyclases; Animals; Corpus Striatum; Guanosine Triphosphate; Kinetics; Magnesium; Male; Manganese; Rabbits | 1980 |
Adenosine receptor-mediated inhibition of rat cerebral cortical adenylate cyclase by a GTP-dependent process.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adenylyl Cyclases; Animals; Cerebral Cortex; Guanosine Triphosphate; In Vitro Techniques; Kinetics; Phenylisopropyladenosine; Rats; Receptors, Cell Surface; Receptors, Purinergic; Sodium Chloride | 1980 |
Methylxanthines modulate adenosine release from slices of cerebral cortex.
Topics: 1-Methyl-3-isobutylxanthine; Adenine; Adenosine; Adenosine Triphosphatases; Aminophylline; Animals; Caffeine; Cerebral Cortex; Cyclic AMP; gamma-Aminobutyric Acid; Male; Mice; Ouabain; Theophylline; Xanthines | 1981 |
IgE-mediated histamine release from human basophils: differences between antigen E- and anti-IgE-induced secretion.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Antibodies, Anti-Idiotypic; Antigens; Basophils; Dimaprit; Dose-Response Relationship, Immunologic; Histamine Release; Humans; Immunoglobulin E; Kinetics; Phosphodiesterase Inhibitors; Thiourea | 1981 |
Impaired adenylate cyclase activity of phenylhydrazine-induced reticulocytes.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adenylyl Cyclases; Anemia; Animals; Drug Antagonism; Erythrocyte Membrane; Erythrocytes; Female; Kinetics; Phenylhydrazines; Rabbits; Reticulocytes; Vasodilator Agents | 1982 |
Regulation of hepatocyte cAMP and pyruvate kinase by site-specific analogs of adenosine.
Topics: 1-Methyl-3-isobutylxanthine; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenosine; Adenylyl Cyclases; Animals; Cyclic AMP; Deoxyadenosines; Dideoxyadenosine; Epinephrine; Liver; Male; Phenylisopropyladenosine; Pyruvate Kinase; Rats; Rats, Inbred Strains | 1982 |
Sensitivity of Ca-dependent slow action potentials to methacholine is induced by phosphodiesterase inhibitors in embryonic chick ventricles.
Topics: 1-Methyl-3-isobutylxanthine; Action Potentials; Adenosine; Angiotensin II; Animals; Calcium; Chick Embryo; Cyclic AMP; Heart; Heart Ventricles; Imidazoles; Methacholine Chloride; Methacholine Compounds; Myocardium; Phosphodiesterase Inhibitors; Xanthines | 1982 |
Adenosine-elicited accumulation of adenosine 3', 5'-cyclic monophosphate in the chick embryo retina.
Topics: 1-Methyl-3-isobutylxanthine; 2-Chloroadenosine; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenosine; Animals; Cells, Cultured; Chick Embryo; Cyclic AMP; Dopamine Antagonists; Retina | 1982 |
Inhibition by cholera toxin of the antilipolytic action of prostanoids, N6-(phenylisopropyl) adenosine and insulin.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adipose Tissue; Alprostadil; Animals; Cholera Toxin; Cyclic AMP; Epoprostenol; Fatty Acids, Nonesterified; Insulin; Isoproterenol; Lipolysis; Male; Phenylisopropyladenosine; Prostaglandins; Prostaglandins E; Rats; Rats, Inbred Strains | 1982 |
Mechanism of action of ATP on intestinal epithelial cells. Cyclic AMP-mediated stimulation of active ion transport.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Alprostadil; Animals; Biological Transport, Active; Cyclic AMP; Guanylyl Imidodiphosphate; Guinea Pigs; Intestine, Small; Kinetics; Male; Prostaglandins E; Vasoactive Intestinal Peptide | 1982 |
Dispersed human lung mast cells. Pharmacologic aspects and comparison with human lung tissue fragments.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Cells, Cultured; Culture Techniques; Deuterium; Dimaprit; Dinoprostone; Fenoterol; Histamine Release; Humans; Immunoglobulin E; Lung; Mast Cells; Prostaglandins E; Stimulation, Chemical; Thiourea | 1982 |
Differential mitogenic effects of methyl isobutyl xanthine and a tumor growth factor on G1-arrested 3T3 T proadipocytes at the predifferentiation GD state and the growth-factor deficiency GS state.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adipose Tissue; Animals; Cell Count; Cell Differentiation; Cell Line; Epidermal Growth Factor; Growth Substances; Interphase; Mice; Mitogens; Structure-Activity Relationship; Theophylline | 1983 |
Regulation of adenylate cyclase in cultured cardiocytes from neonatal rats by adenosine and other agonists.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adenylyl Cyclases; Animals; Animals, Newborn; Catecholamines; Cells, Cultured; Colforsin; Diterpenes; Enzyme Activation; Guanosine Triphosphate; Microscopy, Electron; Myocardium; Rats; Receptors, Cell Surface; Receptors, Purinergic | 1983 |
Phosphatidic acid and phosphatidylinositol labelling in adipose tissue. The role of endogenously formed adenosine.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adenosine Deaminase; Adipose Tissue; Animals; Clonidine; Cricetinae; In Vitro Techniques; Isoproterenol; Mesocricetus; Methoxamine; Phosphatidylinositols; Phospholipids | 1983 |
Neuropharmacology of 3-isobutylmethylxanthine: effects on central noradrenergic systems in vivo.
Topics: 1-Methyl-3-isobutylxanthine; 2-Chloroadenosine; Adenosine; Animals; Axons; Brain; Clonidine; Diazepam; Dihydroxyphenylalanine; Hydroxylation; Male; Methoxyhydroxyphenylglycol; Neurons; Norepinephrine; Rats; Rats, Inbred Strains; Stimulation, Chemical; Theophylline; Tyrosine 3-Monooxygenase; Yohimbine | 1983 |
Endogenous adenosine inhibits excitatory transmission in the rat olfactory cortex slice.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Animals; Aspartic Acid; Central Nervous System; Cerebral Cortex; Cyclic AMP; Electric Stimulation; Male; Olfactory Pathways; Potassium; Rats; Synaptic Transmission; Theophylline | 1983 |
Promotion of lipolysis in rat adipocytes by pertussis toxin: reversal of endogenous inhibition.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Adipose Tissue; Animals; Bacterial Toxins; Bordetella pertussis; Cholera Toxin; Cyclic AMP; Kinetics; Lipid Mobilization; Male; Pertussis Toxin; Rats; Virulence Factors, Bordetella | 1983 |
Effect of adenosine on synthesis and release of cyclic AMP by cultured vascular cells from swine.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Animals; Cells, Cultured; Cyclic AMP; Endothelium; In Vitro Techniques; Kinetics; Muscle, Smooth, Vascular; Radioimmunoassay; Swine | 1983 |
Agents that activate cyclic AMP-dependent protein kinase inhibit explant culture growth and mitotic activity.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Animals; Cell Division; Culture Techniques; Cyclic AMP; Dinoprost; Dinoprostone; Enzyme Activation; Epinephrine; Histamine; Mitosis; Prostaglandins E; Prostaglandins F; Protein Kinases; Skin; Swine; Theophylline | 1983 |
Control of brown adipose tissue lipolysis and respiration by adenosine.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adenosine Deaminase; Adipose Tissue, Brown; Animals; Bucladesine; Cricetinae; Isoproterenol; Kinetics; Lipolysis; Mesocricetus; Oxygen Consumption; Palmitic Acid; Palmitic Acids | 1983 |
Effects of analogues of adenosine and methyl xanthines on insulin sensitivity in soleus muscle of the rat.
Topics: 1-Methyl-3-isobutylxanthine; 2-Chloroadenosine; Adenosine; Animals; Glucose; Glycogen; Glycolysis; Insulin; Lactates; Lactic Acid; Muscles; Phenylisopropyladenosine; Rats; Theophylline | 1984 |
Role of adenosine as an endogenous regulator of respiration in hamster brown adipocytes.
Topics: 1-Methyl-3-isobutylxanthine; 2-Chloroadenosine; Adenosine; Adenosine Deaminase; Adipose Tissue, Brown; Animals; Cricetinae; Deoxyadenosines; Dideoxyadenosine; Isoproterenol; Lipolysis; Male; Mesocricetus; Oxygen Consumption | 1984 |
The possible involvement of adenylate cyclase inhibition in the field potential suppression through alpha-2 adrenergic receptors in the bed nucleus of the stria terminalis.
Topics: 1-Methyl-3-isobutylxanthine; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenosine; Adenylyl Cyclase Inhibitors; Animals; Bucladesine; Deoxyadenosines; Diencephalon; Drug Interactions; Electrophysiology; Guinea Pigs; Norepinephrine; Receptors, Adrenergic, alpha; Thionucleosides | 1984 |
Inhibition of the transport of adenosine, other nucleosides and hypoxanthine in novikoff rat hepatoma cells by methylxanthines, papaverine, N6-cyclohexyladenosine and N6-phenylisopropyladenosine.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Animals; Biological Transport, Active; Caffeine; Cell Line; Hypoxanthine; Hypoxanthines; Liver Neoplasms, Experimental; Papaverine; Phenylisopropyladenosine; Rats; Theophylline; Uridine; Xanthines | 1984 |
Inhibitory actions of adenosine on follicle-stimulating hormone-induced differentiation of cultured rat granulosa cells.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Animals; Cell Differentiation; Cells, Cultured; Colforsin; Cyclic AMP; Dipyridamole; Diterpenes; Female; Follicle Stimulating Hormone; Granulosa Cells; Rats; Receptors, Cell Surface; Receptors, LH | 1984 |
Behavioral and molecular actions of caffeine: focus on adenosine.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Animals; Anxiety Disorders; Behavior; Caffeine; Child; Cyclic AMP; Diagnosis, Differential; Humans; Male; Phenylisopropyladenosine; Psychomotor Performance; Rats; Receptors, Cell Surface; Receptors, Purinergic; Seizures; Sleep Initiation and Maintenance Disorders; Stimulation, Chemical; Tea; Xanthines | 1984 |
Potentiation of antiaggregating activity of adenosine by a phosphodiesterase inhibitor, EG626 (oxagrelate), in human platelets in vitro.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Adenosine; Adenosine Deaminase Inhibitors; Adenylyl Cyclases; Coformycin; Collagen; Cyclic AMP; Drug Synergism; Humans; In Vitro Techniques; Male; Pentostatin; Phosphodiesterase Inhibitors; Phthalazines; Platelet Aggregation; Pyridazines | 1984 |
Behavioral interaction of adenosine and methylxanthines on central purinergic systems.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Brain; Caffeine; Drug Interactions; Male; Mice; Mice, Inbred ICR; Motor Activity; Papaverine; Theophylline | 1984 |
Adenosine and adenosine analogues stimulate adenosine cyclic 3', 5'-monophosphate-dependent chloride secretion in the mammalian ileum.
Topics: 1-Methyl-3-isobutylxanthine; 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Biological Transport; Chlorides; Cyclic AMP; Cyclic GMP; Ileum; Kinetics; Male; Phenylisopropyladenosine; Rabbits; Theophylline | 1984 |
Purine modulation of the hormonal response of the rat Sertoli cell in culture.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Animals; Binding, Competitive; Bucladesine; Cells, Cultured; Coformycin; Cyclic AMP; Follicle Stimulating Hormone; Isoproterenol; Male; Pentostatin; Phenylisopropyladenosine; Rats; Rats, Inbred Strains; Sertoli Cells | 1984 |
Nicotinamide adenine dinucleotides mimic adenosine inhibition on synaptic transmission by decreasing glutamate release in rat hippocampal slices.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Amino Acids; Animals; Electrophysiology; Female; Glutamates; Glutamic Acid; Hippocampus; In Vitro Techniques; NAD; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Synapses; Synaptic Transmission | 1993 |
Histamine H3-receptor-induced inhibition of duodenal cholinergic transmission is independent of intracellular cyclic AMP and GMP.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Adenosine; Animals; Clonidine; Colforsin; Cyclic AMP; Cyclic GMP; Duodenum; Guinea Pigs; Histamine Agonists; In Vitro Techniques; Male; Methylhistamines; Parasympathetic Nervous System; Receptors, Histamine H3; Signal Transduction; Synaptic Transmission | 1993 |
3-isobutyl-1-methylxanthine decreases renal cortical interstitial levels of adenosine and inosine.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Animals; Blood Pressure; Extracellular Space; Inosine; Kidney Cortex; Male; Rats; Rats, Sprague-Dawley; Regional Blood Flow | 1994 |
Enhancement of differentiation induction of mouse myelomonocytic leukemic cells by extracellular ATP.
Topics: 1-Methyl-3-isobutylxanthine; Actins; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Calcium; Cell Differentiation; Cytosol; Dose-Response Relationship, Drug; Interleukin-6; Kinetics; Leukemia, Experimental; Leukemia, Myeloid; Mice; Phagocytosis; Protein Synthesis Inhibitors; Proto-Oncogene Proteins c-jun; Proto-Oncogene Proteins c-myc; Receptors, Fc; Recombinant Proteins; Triazines; Tumor Cells, Cultured | 1994 |
Cyclic AMP stimulates K+ channel activity in mesophyll cells of Vicia faba L.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Adenosine; Animals; Brain; Bucladesine; Cattle; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Electric Stimulation; Fabaceae; Guanosine Monophosphate; Intercellular Signaling Peptides and Proteins; Kinetics; Macromolecular Substances; Membrane Potentials; Organothiophosphorus Compounds; Peptides; Plants, Medicinal; Potassium Channels | 1994 |
Is cyclic AMP involved in excitatory amino acid-evoked adenosine release from rat cortical slices?
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Animals; Calcium; Chromatography, High Pressure Liquid; Colforsin; Cyclic AMP; Excitatory Amino Acids; Male; N-Methylaspartate; Parietal Lobe; Probenecid; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 1994 |
Binding thermodynamics of adenosine A2a receptor ligands.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Binding Sites; Brain Chemistry; In Vitro Techniques; Ligands; Male; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Temperature; Thermodynamics; Xanthines | 1995 |
Modulation of inspiratory drive to phrenic motoneurons by presynaptic adenosine A1 receptors.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Animals; Animals, Newborn; Brain Stem; Evoked Potentials; In Vitro Techniques; Inhalation; Motor Neurons; Patch-Clamp Techniques; Phrenic Nerve; Rats; Receptors, Purinergic P1; Respiration; Spinal Cord; Synaptic Transmission; Time Factors | 1995 |
Metabolism of exogenous cyclic AMP to adenosine in the rat kidney.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Animals; Cyclic AMP; Kidney; Male; Rats; Rats, Sprague-Dawley; Xanthines | 1995 |
ATPo but not cAMPi activates a chloride conductance in mouse ventricular myocytes.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adenosine Triphosphate; Animals; Cells, Cultured; Chloride Channels; Colforsin; Cyclic AMP; Cystic Fibrosis; Isoproterenol; Membrane Potentials; Mice; Mice, Knockout; Myocardium; Patch-Clamp Techniques; Stimulation, Chemical | 1995 |
Locomotor activity in mice during chronic treatment with caffeine and withdrawal.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Animals; Caffeine; Dopamine Agents; Dose-Response Relationship, Drug; Male; Mice; Motor Activity; Parasympathomimetics; Substance Withdrawal Syndrome; Xanthines | 1993 |
Comparison of the effect of isobutylmethylxanthine and phosphodiesterase-selective inhibitors on cAMP levels in SH-SY5Y neuroblastoma cells.
Topics: 1-Methyl-3-isobutylxanthine; 2-Chloroadenosine; Adenosine; Adenylyl Cyclase Inhibitors; Cell Line; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Humans; Neuroblastoma; Phosphodiesterase Inhibitors; Pyrrolidinones; Rolipram; Tumor Cells, Cultured | 1993 |
Bradykinin inhibits cyclic AMP accumulation in D384-human astrocytoma cells via a calcium-dependent inhibition of adenylyl cyclase.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adenylyl Cyclase Inhibitors; Astrocytoma; Bradykinin; Brain Neoplasms; Calcimycin; Calcium; Calmodulin; Colforsin; Cyclic AMP; Dopamine; Egtazic Acid; Humans; Hydroquinones; Inositol 1,4,5-Trisphosphate; Neoplasm Proteins; Pyrrolidinones; Rolipram; Signal Transduction; Tumor Cells, Cultured | 1993 |
Adenosine inhibits efferent function of extrinsic capsaicin-sensitive sensory nerves in the enteric nervous system.
Topics: 1-Methyl-3-isobutylxanthine; Acetylcholine; Adenosine; Animals; Capsaicin; Electric Stimulation; Electrophysiology; Female; Gastrointestinal Motility; Guinea Pigs; Ileum; In Vitro Techniques; Male; Mesentery; Muscle Contraction; Myenteric Plexus; Nerve Fibers; Neurons, Afferent; Neurons, Efferent; Substance P; Theophylline | 1993 |
Existence of rolipram-sensitive phosphodiesterase in rat megakaryocyte.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adenosine Diphosphate; Adenylyl Cyclases; Animals; Bone Marrow Cells; Calcimycin; Calcium Channels; Colforsin; Cyclic AMP; Electrophysiology; Female; In Vitro Techniques; Inosine Triphosphate; Isoquinolines; Male; Megakaryocytes; Nystatin; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Protein Kinase C; Pyrrolidinones; Rats; Rats, Wistar; Rolipram | 1993 |
Changes in adenosine A1- and A2-receptor expression during adipose cell differentiation.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adipose Tissue; Animals; Blotting, Northern; Cell Differentiation; Cells, Cultured; Cyclic AMP; Dexamethasone; Humans; Lipolysis; Mice; Phenylisopropyladenosine; Receptors, Purinergic P1 | 1996 |
Adenosine inhibits L- and N-type calcium channels in pituitary melanotrophs. Evidence for the involvement of a G protein in calcium channel gating.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adenylate Cyclase Toxin; Animals; Calcium Channel Blockers; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; Electrophysiology; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Ion Channel Gating; Melanocyte-Stimulating Hormones; Membrane Potentials; Patch-Clamp Techniques; Pertussis Toxin; Phenylisopropyladenosine; Phosphodiesterase Inhibitors; Pituitary Gland; Rana ridibunda; Virulence Factors, Bordetella | 1996 |
Cyclic AMP-adenosine pathway inhibits vascular smooth muscle cell growth.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Animals; Cardiovascular Agents; Cells, Cultured; Chromatography, High Pressure Liquid; Cyclic AMP; DNA; Inosine; Male; Muscle Development; Muscle, Smooth, Vascular; Phosphodiesterase Inhibitors; Rats; Rats, Sprague-Dawley | 1996 |
Adenosine increases the cAMP content of the rat carotid body in vitro.
Topics: 1-Methyl-3-isobutylxanthine; 2-Chloroadenosine; Adenine; Adenosine; Animals; Carotid Body; Cyclic AMP; Male; Nerve Tissue Proteins; Perfusion; Phenethylamines; Rats; Rats, Wistar; Receptors, Purinergic P1; Second Messenger Systems | 1996 |
Adenosine stimulation of DNA synthesis in human endothelial cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 1-Methyl-3-isobutylxanthine; Adenosine; Adenosine Triphosphate; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; DNA; Endothelium, Vascular; Humans; Kinetics; Poly A; Purinergic P1 Receptor Antagonists; Quinazolines; Tetradecanoylphorbol Acetate; Thioinosine; Thionucleotides; Thymidine; Triazoles; Umbilical Veins | 1997 |
Acute effects of progesterone on glucose metabolism in rat adipocytes: are they modulated by endogenous adenosine?
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adenosine Deaminase; Adipocytes; Animals; Cyclic AMP; Female; Glucose; Glycerol; Isoproterenol; Kinetics; Lipolysis; Progesterone; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Xanthines | 1997 |
[Early stages in mechanisms of glucocorticoids action on human thrombocytes: effect of hydrocortisone on intracellular cAMP and Ca2+].
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Blood Platelets; Calcium; Colforsin; Collagen; Cyclic AMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Epinephrine; Glucocorticoids; Humans; Hydrocortisone; Intracellular Fluid; Phosphodiesterase Inhibitors; Radioligand Assay; Thapsigargin | 1997 |
Metabolism of cAMP to adenosine in the renal vasculature.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Animals; Cells, Cultured; Cyclic AMP; Male; Muscle, Smooth, Vascular; Perfusion; Probenecid; Rats; Rats, Sprague-Dawley; Renal Veins | 1997 |
The role of cyclic AMP as a precursor of extracellular adenosine in the rat hippocampus.
Topics: 1-Methyl-3-isobutylxanthine; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenosine; Adenosine Deaminase; Adenosine Diphosphate; Animals; Colforsin; Cyclic AMP; Diterpenes; Enzyme Inhibitors; Excitatory Postsynaptic Potentials; Guanosine Monophosphate; Hippocampus; In Vitro Techniques; Male; Patch-Clamp Techniques; Phosphodiesterase Inhibitors; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Theophylline | 1997 |
Regulation of vascular endothelial growth factor expression by cAMP in rat aortic smooth muscle cells.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adenylyl Cyclases; Animals; Aorta; Cobalt; Colforsin; Cyclic AMP; Endothelial Growth Factors; Endothelium, Vascular; Enzyme Activation; Fibroblasts; Gene Expression Regulation; Iloprost; Isoproterenol; Lymphokines; Muscle, Smooth, Vascular; Phosphodiesterase Inhibitors; Rats; RNA, Messenger; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 1998 |
Inhibition of recombinant human cardiac L-type Ca2+ channel alpha1C subunits by 3-isobutyl-1-methylxanthine.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Barium; Calcium Channel Blockers; Calcium Channels; Clone Cells; Flavins; Heart; Humans; Membrane Potentials; Myocardium; Patch-Clamp Techniques; Phosphodiesterase Inhibitors; Recombinant Proteins | 1998 |
P2X receptors in cochlear Deiters' cells.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Calcium; Cochlea; Colforsin; Dose-Response Relationship, Drug; Enzyme Activation; Guinea Pigs; Patch-Clamp Techniques; Protein Kinases; Purinergic P2 Receptor Agonists; Receptors, Purinergic P2; Receptors, Purinergic P2X2; Tetradecanoylphorbol Acetate; Thionucleotides; Uridine Triphosphate; Vasodilator Agents; Vestibular Nucleus, Lateral | 1998 |
Evidence for an endogenous cAMP-adenosine pathway in the rat kidney.
Topics: 1-Methyl-3-isobutylxanthine; 5'-Nucleotidase; Adenosine; Adrenergic beta-Agonists; Animals; Cyclic AMP; Hypoxanthine; Inosine; Isoproterenol; Kidney; Male; Perfusion; Phosphodiesterase Inhibitors; Propranolol; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta | 1998 |
Effects of ethanol on basal and adenosine-induced increases in beta-endorphin release and intracellular cAMP levels in hypothalamic cells.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Animals; beta-Endorphin; Cells, Cultured; Cyclic AMP; Drug Synergism; Ethanol; Hypothalamus; Intracellular Membranes; Neurons; Phenylisopropyladenosine; Rats; Rats, Sprague-Dawley | 1999 |
P2 purinoceptors contribute to ATP-induced inhibition of L-type Ca2+ current in rabbit atrial myocytes.
Topics: 1-Methyl-3-isobutylxanthine; 5'-Nucleotidase; 8-Bromo Cyclic Adenosine Monophosphate; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Adrenergic beta-Agonists; Animals; Calcium-Transporting ATPases; Colforsin; Cyclic AMP; Enzyme Inhibitors; Isoproterenol; Myocardium; Patch-Clamp Techniques; Pertussis Toxin; Potassium Channels; Potassium Channels, Voltage-Gated; Purinergic P1 Receptor Antagonists; Purinergic P2 Receptor Antagonists; Rabbits; Receptors, Purinergic P2; Shal Potassium Channels; Suramin; Virulence Factors, Bordetella; Xanthines | 1999 |
AMP deaminase in piglet cardiac myocytes: effect on nucleotide metabolism during ischemia.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; AMP Deaminase; Animals; Animals, Newborn; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Carcinogens; Carotenoids; Cells, Cultured; Cyclic AMP; Energy Metabolism; Enzyme Activation; Heart Ventricles; Ischemic Preconditioning; Muscle Fibers, Skeletal; Myocardial Ischemia; Myocardium; Oxygenases; Phosphodiesterase Inhibitors; Swine; Tetradecanoylphorbol Acetate; Uncoupling Agents | 1999 |
Effects of A1-adenosine receptor antagonists on purinergic transmission in the guinea-pig vas deferens in vitro.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adenosine Triphosphate; Adrenergic alpha-Antagonists; Animals; Guinea Pigs; In Vitro Techniques; Male; Membrane Potentials; Neuroeffector Junction; Phentolamine; Phosphodiesterase Inhibitors; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Synaptic Transmission; Theophylline; Thioinosine; Vas Deferens; Xanthines; Yohimbine | 1999 |
Histamine H(2) receptor activated chloride conductance in myenteric neurons from guinea pig small intestine.
Topics: 1-Methyl-3-isobutylxanthine; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Adenosine; Animals; Calcium Channel Blockers; Chlorides; Cyclic AMP; Cyclooxygenase Inhibitors; Electric Conductivity; Enzyme Inhibitors; Excitatory Postsynaptic Potentials; Guinea Pigs; Histamine; Intestine, Small; Membrane Potentials; Myenteric Plexus; Neurons; Niflumic Acid; omega-Conotoxins; Paracrine Communication; Patch-Clamp Techniques; Phosphodiesterase Inhibitors; Purinergic P1 Receptor Agonists; Receptors, Histamine H2; Stress, Psychological; Theophylline; Thionucleotides | 2000 |
Cardiac fibroblasts express the cAMP-adenosine pathway.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Adenosine; Adenosine Monophosphate; Analysis of Variance; Animals; Cell Division; Cells, Cultured; Cyclic AMP; Extracellular Space; Fibroblasts; Inosine; Male; Myocardium; Phosphodiesterase Inhibitors; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Xanthines | 2000 |
Preglomerular microcirculation expresses the cAMP-adenosine pathway.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adenylyl Cyclases; Animals; Cyclic AMP; Isoproterenol; Kidney Glomerulus; Male; Microcirculation; Rats; Xanthines | 2000 |
Leptin-induced lipolysis opposes the tonic inhibition of endogenous adenosine in white adipocytes.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adenylate Cyclase Toxin; Adipocytes; Adipose Tissue; Animals; Bucladesine; Cells, Cultured; Colforsin; Kinetics; Leptin; Lipolysis; Male; Obesity; Purinergic P1 Receptor Antagonists; Rats; Rats, Mutant Strains; Rats, Zucker; Recombinant Proteins; Signal Transduction; Virulence Factors, Bordetella | 2001 |
Adenosine biosynthesis in the collecting duct.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adenosine Monophosphate; Adenosine Triphosphate; Adenylyl Cyclases; Animals; Blotting, Western; Cyclic AMP; Epithelial Cells; In Vitro Techniques; Kidney Tubules, Collecting; Nephrons; Phosphodiesterase Inhibitors; Rats; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Xanthines | 2003 |
Adenosine and cAMP are potent inhibitors of the NF-kappa B pathway downstream of immunoreceptors.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Animals; Antigens, CD; Antigens, Differentiation, T-Lymphocyte; B-Lymphocytes; Cell Line; Cell Survival; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; I-kappa B Proteins; Lectins, C-Type; Lipopolysaccharides; MAP Kinase Signaling System; Mast Cells; Mice; NF-kappa B; NF-KappaB Inhibitor alpha; Phosphorylation; Receptors, Antigen, B-Cell; Receptors, IgG; Receptors, Immunologic; Signal Transduction | 2005 |
Adenosine signaling promotes neuronal, catecholaminergic differentiation of primary neural crest cells and CNS-derived CAD cells.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Adenosine-5'-(N-ethylcarboxamide); Adrenal Medulla; Animals; Bone Morphogenetic Protein 2; Bone Morphogenetic Proteins; Catecholamines; Cell Differentiation; Cell Line; Cells, Cultured; Chromaffin Cells; Coturnix; Culture Media, Serum-Free; Cyclic AMP; Neural Crest; Neurons; Quinazolines; Receptor, Adenosine A2A; Receptor, Adenosine A2B; Signal Transduction; Sympathetic Nervous System; Transforming Growth Factor beta; Triazoles; Tyrosine 3-Monooxygenase | 2005 |
The extracellular cAMP-adenosine pathway significantly contributes to the in vivo production of adenosine.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Animals; Cyclic AMP; Hypertension; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Sprague-Dawley; Xanthines | 2007 |
Altering cAMP levels within a central pattern generator modifies or disrupts rhythmic motor output.
Topics: 1-Methyl-3-isobutylxanthine; Action Potentials; Adenosine; Animals; Central Nervous System; Cyclic AMP; Cyclic CMP; Electric Stimulation; Enzyme Inhibitors; Mollusca; Motor Activity; Neurons; Periodicity; Phenethylamines; Photolysis | 2007 |
Major histocompatibility class II transactivator expression in smooth muscle cells from A2b adenosine receptor knock-out mice: cross-talk between the adenosine and interferon-gamma signaling.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adenylyl Cyclases; Animals; Cells, Cultured; Collagen; Cyclic AMP; Down-Regulation; Interferon-gamma; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscle, Smooth; Nuclear Proteins; Phosphodiesterase Inhibitors; Receptor, Adenosine A2B; Signal Transduction; Trans-Activators | 2008 |
An antagonistic interaction between A2B adenosine and D2 dopamine receptors modulates the function of rat carotid body chemoreceptor cells.
Topics: 1-Methyl-3-isobutylxanthine; Acetamides; Adenosine; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Adenosine-5'-(N-ethylcarboxamide); Animals; Caffeine; Carotid Body; Catecholamines; Chemoreceptor Cells; Cyclic AMP; Dopamine Agents; Dopamine D2 Receptor Antagonists; Dose-Response Relationship, Drug; Drug Interactions; Female; Male; Oxygen; Phenethylamines; Phosphodiesterase Inhibitors; Purines; Rats; Rats, Wistar; Receptor, Adenosine A2B; Receptors, Dopamine D2; Tritium; Vasodilator Agents | 2008 |
The relationship between pulsatile GnRH secretion and cAMP production in immortalized GnRH neurons.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Animals; Cell Line; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Gonadotropin-Releasing Hormone; Humans; Isoquinolines; Neurons; Phosphodiesterase Inhibitors; Protein Kinase Inhibitors; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Sulfonamides | 2011 |
Expression of the 2',3'-cAMP-adenosine pathway in astrocytes and microglia.
Topics: 1-Methyl-3-isobutylxanthine; 5'-Nucleotidase; Adenine Nucleotides; Adenosine; Animals; Astrocytes; Cell Separation; Chromatography, High Pressure Liquid; Cyclic AMP; Female; Fluorescent Antibody Technique; Male; Mice; Mice, Inbred C57BL; Microglia; Phosphodiesterase Inhibitors; Signal Transduction; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Xanthines | 2011 |
The phosphodiesterase inhibitor isobutylmethylxanthine attenuates behavioral sensitization to cocaine.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Animals; Behavior, Addictive; Behavior, Animal; Cocaine; Cyclic AMP; Male; Motor Activity; Phosphodiesterase Inhibitors; Rats; Rats, Sprague-Dawley | 2012 |
Extracellular 2',3'-cAMP-adenosine pathway in proximal tubular, thick ascending limb, and collecting duct epithelial cells.
Topics: 1-Methyl-3-isobutylxanthine; Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Animals; Epithelial Cells; Kidney Tubules, Collecting; Kidney Tubules, Proximal; Loop of Henle; Male; Rats; Rats, Sprague-Dawley; Xanthines | 2013 |
Cyclic AMP efflux, via MRPs and A1 adenosine receptors, is critical for bovine sperm capacitation.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adenosine A1 Receptor Antagonists; Adenylyl Cyclase Inhibitors; Animals; Bicarbonates; Biological Transport; Cattle; Cyclic AMP; Humans; Male; Multidrug Resistance-Associated Proteins; Phosphodiesterase Inhibitors; Probenecid; Receptor, Adenosine A1; Sperm Capacitation; Sperm Motility; Spermatozoa; Xanthines | 2014 |
Role of CNPase in the oligodendrocytic extracellular 2',3'-cAMP-adenosine pathway.
Topics: 1-Methyl-3-isobutylxanthine; 2',3'-Cyclic-Nucleotide Phosphodiesterases; Adenine Nucleotides; Adenosine; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Cells, Cultured; Embryo, Mammalian; Extracellular Fluid; Mice; Mice, Transgenic; Neurons; Oligodendroglia; Phosphodiesterase Inhibitors; Signal Transduction | 2013 |
Participation of the adenosine salvage pathway and cyclic AMP modulation in oocyte energy metabolism.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; AMP-Activated Protein Kinases; Animals; Bucladesine; Coculture Techniques; Colforsin; Cumulus Cells; Cyclic AMP; Energy Metabolism; Female; Gap Junctions; Gene Expression; In Vitro Oocyte Maturation Techniques; Meiosis; Mice; Oocytes | 2019 |
Cyclic adenosine monophosphate (cAMP) analog and phosphodiesterase inhibitor (IBMX) ameliorate human sperm capacitation and motility.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adenosine Monophosphate; Chlortetracycline; Cyclic AMP; Humans; Infertility; Male; Phosphodiesterase Inhibitors; Semen; Sperm Capacitation; Sperm Motility | 2022 |