1-methyl-3-isobutylxanthine and adenosine-5'-(n-ethylcarboxamide)

1-methyl-3-isobutylxanthine has been researched along with adenosine-5'-(n-ethylcarboxamide) in 34 studies

Research

Studies (34)

TimeframeStudies, this research(%)All Research%
pre-199016 (47.06)18.7374
1990's13 (38.24)18.2507
2000's4 (11.76)29.6817
2010's1 (2.94)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Browne, RG; Howard, HR; Koe, BK; Lebel, LA; Sarges, R; Seymour, PA1
Daly, JW1
Bertin, B; Freissmuth, M; Hohenegger, M; Jockers, R; Linder, ME; Marullo, S; Nanoff, C; Strosberg, AD1
Borea, PA; Dalpiaz, A; Gilli, G; Gilli, P; Scatturin, A; Varani, K1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Ahn, S; Cheong, JH; Jacobson, KA; Jeong, LS; Jin, SH; Kim, G; Kim, HJ; Kim, J; Lee, E; Lee, M; Noh, M; Yu, J1
Ishimura, Y; Kizaki, H; Suzuki, K; Tadakuma, T1
Alonso, MJ; Ibañez, C; Marín, J; Reviriego, J1
Greenfield, LJ; Hackett, JT; Linden, J1
Canonico, PL; Catania, MV; Nicoletti, F; Rampello, L; Sortino, MA1
Gunther, GR; Herring, MB1
Ali, H; Beaven, MA; Daly, JW; Müller, CE1
Cai, SD; Qiu, YG; Wei, XD; You, SX1
Kitos, TE; Michaelis, ML; Mooney, T1
Anand-Srivastava, MB; Cantin, M; Gutkowska, J1
Coffin, VL; Spealman, RD1
Anand-Srivastava, MB1
Fox, IH; John, D1
Dodd, PR; Johnston, GA; Watson, WE1
Arend, LJ; Smith, WL; Sonnenburg, WK; Spielman, WS1
Blazynski, C1
Belloni, FL; Gerritsen, ME; Liang, BC1
Keery, RJ; Lumley, P1
Arend, LJ; Gusovsky, F; Handler, JS; Rhim, JS; Spielman, WS1
Jackman, SA; Nicholson, CD; Wilke, R1
Cooper, DM; Jagus, R1
Altman, HJ; Barraco, RA; Coffin, VL; Phillis, JW; Taylor, JA1
Dobbins, JW; Forrest, JN; Laurenson, JP1
Borea, PA; Dalpiaz, A; Gilli, G; Guerra, L; Varani, K1
Altiok, N; Fredholm, BB1
Ailhaud, G; Børglum, JD; Darimont, C; Gaillard, D; Négrel, R; Richelsen, B; Vassaux, G1
Culić, O; Gruwel, ML; Muhs, A; Schrader, J; Williams, JP1
Andrisani, OM; Bilodeau, ML; Ji, M; Paris, M1
Batuca, JR; Conde, SV; Gonzalez, C; Monteiro, EC; Obeso, A1

Reviews

1 review(s) available for 1-methyl-3-isobutylxanthine and adenosine-5'-(n-ethylcarboxamide)

ArticleYear
Adenosine receptors: targets for future drugs.
    Journal of medicinal chemistry, 1982, Volume: 25, Issue:3

    Topics: Adenosine; Adenosine Triphosphate; Animals; Humans; Ligands; Receptors, Cell Surface; Receptors, Purinergic; Structure-Activity Relationship; Xanthines

1982

Other Studies

33 other study(ies) available for 1-methyl-3-isobutylxanthine and adenosine-5'-(n-ethylcarboxamide)

ArticleYear
4-Amino[1,2,4]triazolo[4,3-a]quinoxalines. A novel class of potent adenosine receptor antagonists and potential rapid-onset antidepressants.
    Journal of medicinal chemistry, 1990, Volume: 33, Issue:8

    Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Antidepressive Agents; Behavior, Animal; Caffeine; Cats; Cell Membrane; Cerebral Cortex; Chemical Phenomena; Chemistry; Corpus Striatum; Male; Molecular Structure; Motor Activity; Purinergic Antagonists; Quinoxalines; Rats; Receptors, Purinergic; Sleep; Structure-Activity Relationship; Triazoles

1990
Species difference in the G protein selectivity of the human and bovine A1-adenosine receptor.
    The Journal of biological chemistry, 1994, Dec-23, Volume: 269, Issue:51

    Topics: Animals; Base Sequence; Brain; Cattle; DNA Primers; Escherichia coli; GTP-Binding Proteins; Humans; Molecular Sequence Data; Protein Binding; Receptors, Purinergic P1; Recombinant Proteins; Species Specificity

1994
Binding thermodynamics as a tool to investigate the mechanisms of drug-receptor interactions: thermodynamics of cytoplasmic steroid/nuclear receptors in comparison with membrane receptors.
    Journal of medicinal chemistry, 2005, Mar-24, Volume: 48, Issue:6

    Topics: Estradiol; Female; Humans; In Vitro Techniques; Male; Metribolone; Pregnenediones; Prostate; Receptors, Androgen; Receptors, Cell Surface; Receptors, Estrogen; Receptors, Progesterone; Receptors, Steroid; Thermodynamics; Uterus

2005
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Polypharmacology of N
    Journal of medicinal chemistry, 2017, 09-14, Volume: 60, Issue:17

    Topics: Adenosine; Adenosine A3 Receptor Agonists; Adenosine A3 Receptor Antagonists; Adiponectin; Animals; Cell Line; Diabetes Mellitus, Experimental; Humans; Hypoglycemic Agents; Insulin Resistance; Ligands; Male; Mice; Mice, Inbred C57BL; Polypharmacology; PPAR delta; PPAR gamma; Receptor, Adenosine A3

2017
Adenosine receptor-mediated accumulation of cyclic AMP-induced T-lymphocyte death through internucleosomal DNA cleavage.
    The Journal of biological chemistry, 1990, Mar-25, Volume: 265, Issue:9

    Topics: 1-Methyl-3-isobutylxanthine; 2-Chloroadenosine; 8-Bromo Cyclic Adenosine Monophosphate; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Bucladesine; Cell Survival; Cells, Cultured; Cholera Toxin; Colforsin; Cyclic AMP; Kinetics; Male; Mice; Mice, Inbred BALB C; Phenylisopropyladenosine; Receptors, Purinergic; T-Lymphocytes

1990
Action of adenosine and characterization of adenosine receptors in human placental vasculature.
    General pharmacology, 1990, Volume: 21, Issue:2

    Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Blood Vessels; Bucladesine; Calcium Radioisotopes; Cell Membrane Permeability; Cyclic AMP; Dinoprost; Female; Humans; In Vitro Techniques; Muscle Contraction; Muscle, Smooth, Vascular; Phenylisopropyladenosine; Placenta; Potassium; Pregnancy; Receptors, Purinergic

1990
Xenopus oocyte K+ current. III. Phorbol esters and pH regulate current at gap junctions.
    The American journal of physiology, 1990, Volume: 259, Issue:5 Pt 1

    Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Colforsin; Cyclic AMP; Female; Follicle Stimulating Hormone; Hydrogen-Ion Concentration; Intercellular Junctions; Isoproterenol; Kinetics; Mathematics; Models, Biological; Oocytes; Phorbol 12,13-Dibutyrate; Potassium Channels; Xenopus laevis

1990
Adenosine deaminase increases release of excitatory amino acids through a mechanism independent of adenosine depletion.
    Neuropharmacology, 1991, Volume: 30, Issue:2

    Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adenosine Deaminase; Adenosine-5'-(N-ethylcarboxamide); Amino Acids; Animals; Aspartic Acid; Calcium; Calcium Radioisotopes; Cells, Cultured; Cerebellum; Female; Hydrolysis; Phosphatidylinositols; Rats; Rats, Inbred Strains; Theophylline

1991
Inhibition of neutrophil superoxide production by adenosine released from vascular endothelial cells.
    Annals of vascular surgery, 1991, Volume: 5, Issue:4

    Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adenosine Deaminase; Adenosine-5'-(N-ethylcarboxamide); Cells, Cultured; Endothelium, Vascular; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pentostatin; Superoxides; Umbilical Veins

1991
Methylxanthines block antigen-induced responses in RBL-2H3 cells independently of adenosine receptors or cyclic AMP: evidence for inhibition of antigen binding to IgE.
    The Journal of pharmacology and experimental therapeutics, 1991, Volume: 258, Issue:3

    Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Antigens; Cyclic AMP; Dinitrophenols; Immunoglobulin E; Purinergic Antagonists; Rats; Receptors, Purinergic; Serum Albumin, Bovine; Structure-Activity Relationship; Tumor Cells, Cultured; Type C Phospholipases; Vasodilator Agents; Xanthines

1991
Effects of adenosine and its derivatives on cultured myocardial cells and detection of adenosine receptors in rat.
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1991, Volume: 12, Issue:4

    Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Binding, Competitive; Cells, Cultured; Depression, Chemical; Female; Male; Myocardium; Phenylisopropyladenosine; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Purinergic

1991
Characteristics of adenosine binding sites in atrial sarcolemmal membranes.
    Biochimica et biophysica acta, 1985, Jun-27, Volume: 816, Issue:2

    Topics: 1-Methyl-3-isobutylxanthine; 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Binding Sites; Binding, Competitive; Cattle; Endopeptidases; Heart Atria; Myocardium; Sarcolemma; Subcellular Fractions; Theophylline; Time Factors

1985
Adenosine-sensitive adenylate cyclase in rat anterior pituitary.
    Neuroendocrinology, 1985, Volume: 41, Issue:2

    Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adenylyl Cyclases; Animals; Cations, Divalent; Deoxyadenosines; Female; Guanine Nucleotides; In Vitro Techniques; Phenylisopropyladenosine; Pituitary Gland, Anterior; Rats; Rats, Inbred Strains; Theophylline

1985
Modulation of the behavioral effects of chlordiazepoxide by methylxanthines and analogs of adenosine in squirrel monkeys.
    The Journal of pharmacology and experimental therapeutics, 1985, Volume: 235, Issue:3

    Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Caffeine; Chlordiazepoxide; Conditioning, Psychological; Male; Phenylisopropyladenosine; Receptors, Cell Surface; Receptors, Purinergic; Saimiri; Theobromine; Theophylline; Xanthines

1985
Regulation of adenylate cyclase by adenosine and other agonists in rat myocardial sarcolemma.
    Archives of biochemistry and biophysics, 1985, Volume: 243, Issue:2

    Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Catecholamines; Cations, Divalent; Enzyme Activation; Glucagon; Guanine Nucleotides; Myocardium; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Purinergic; Sarcolemma

1985
Characteristics of high affinity and low affinity adenosine binding sites in human cerebral cortex.
    Advances in experimental medicine and biology, 1986, Volume: 195 Pt B

    Topics: 1-Methyl-3-isobutylxanthine; 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Cell Membrane; Cerebral Cortex; Humans; Kinetics; Phenylisopropyladenosine; Receptors, Purinergic; Theophylline

1986
Adenosine receptors in post-mortem human cerebral cortex and the effect of carbamazepine.
    Clinical and experimental pharmacology & physiology, 1986, Volume: 13, Issue:10

    Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Binding, Competitive; Carbamazepine; Cerebral Cortex; Humans; In Vitro Techniques; Kinetics; Phenylisopropyladenosine; Postmortem Changes; Receptors, Purinergic; Software; Theophylline

1986
A1 and A2 adenosine receptors in rabbit cortical collecting tubule cells. Modulation of hormone-stimulated cAMP.
    The Journal of clinical investigation, 1987, Volume: 79, Issue:3

    Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adenylate Cyclase Toxin; Animals; Arginine Vasopressin; Cyclic AMP; Isoproterenol; Kidney Cortex; Kidney Tubules; Kidney Tubules, Collecting; Pertussis Toxin; Phenylisopropyladenosine; Rabbits; Receptors, Purinergic; Virulence Factors, Bordetella; Xanthines

1987
Adenosine A1 receptor-mediated inhibition of adenylate cyclase in rabbit retina.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1987, Volume: 7, Issue:8

    Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adenylyl Cyclases; Animals; Autoradiography; Guanosine Triphosphate; Phenylisopropyladenosine; Rabbits; Receptors, Purinergic; Retina

1987
Effects of alkylxanthines and calcium antagonists on adenosine uptake by cultured rabbit coronary microvascular endothelium.
    Pharmacology, 1987, Volume: 35, Issue:1

    Topics: 1-Methyl-3-isobutylxanthine; Adenine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Calcium Channel Blockers; Cells, Cultured; Coronary Vessels; Dipyridamole; Endothelium; Ethanol; Isoproterenol; Male; Microcirculation; Rabbits; Theophylline; Trifluoperazine; Xanthines

1987
AH6809, a prostaglandin DP-receptor blocking drug on human platelets.
    British journal of pharmacology, 1988, Volume: 94, Issue:3

    Topics: 1-Methyl-3-isobutylxanthine; 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine; Adenosine Diphosphate; Adenosine-5'-(N-ethylcarboxamide); Dinoprost; Epoprostenol; Humans; Hydantoins; In Vitro Techniques; Male; Platelet Activating Factor; Platelet Aggregation; Prostaglandin D2; Prostaglandin Endoperoxides, Synthetic; Receptors, Immunologic; Receptors, Prostaglandin; Xanthenes; Xanthones

1988
Adenosine-sensitive phosphoinositide turnover in a newly established renal cell line.
    The American journal of physiology, 1989, Volume: 256, Issue:6 Pt 2

    Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Calcium; Cell Line; Cyclic AMP; Cyclic GMP; Cytosol; Epithelium; Kidney Tubules, Collecting; Membrane Potentials; Pertussis Toxin; Phosphatidylinositols; Rabbits; Virulence Factors, Bordetella

1989
The ability of denbufylline to inhibit cyclic nucleotide phosphodiesterase and its affinity for adenosine receptors and the adenosine re-uptake site.
    British journal of pharmacology, 1989, Volume: 97, Issue:3

    Topics: 1-Methyl-3-isobutylxanthine; 2',3'-Cyclic-Nucleotide Phosphodiesterases; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Cerebral Cortex; In Vitro Techniques; Kinetics; Male; Myocardium; Phenylisopropyladenosine; Rats; Rats, Inbred Strains; Receptors, Purinergic; Theophylline; Thioinosine; Xanthines

1989
Impaired adenylate cyclase activity of phenylhydrazine-induced reticulocytes.
    The Journal of biological chemistry, 1982, May-10, Volume: 257, Issue:9

    Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adenylyl Cyclases; Anemia; Animals; Drug Antagonism; Erythrocyte Membrane; Erythrocytes; Female; Kinetics; Phenylhydrazines; Rabbits; Reticulocytes; Vasodilator Agents

1982
Behavioral interaction of adenosine and methylxanthines on central purinergic systems.
    Neuroscience letters, 1984, Jun-15, Volume: 47, Issue:2

    Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Brain; Caffeine; Drug Interactions; Male; Mice; Mice, Inbred ICR; Motor Activity; Papaverine; Theophylline

1984
Adenosine and adenosine analogues stimulate adenosine cyclic 3', 5'-monophosphate-dependent chloride secretion in the mammalian ileum.
    The Journal of clinical investigation, 1984, Volume: 74, Issue:3

    Topics: 1-Methyl-3-isobutylxanthine; 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Biological Transport; Chlorides; Cyclic AMP; Cyclic GMP; Ileum; Kinetics; Male; Phenylisopropyladenosine; Rabbits; Theophylline

1984
Binding thermodynamics of adenosine A2a receptor ligands.
    Biochemical pharmacology, 1995, Feb-14, Volume: 49, Issue:4

    Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Binding Sites; Brain Chemistry; In Vitro Techniques; Ligands; Male; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Temperature; Thermodynamics; Xanthines

1995
Bradykinin inhibits cyclic AMP accumulation in D384-human astrocytoma cells via a calcium-dependent inhibition of adenylyl cyclase.
    Cellular signalling, 1993, Volume: 5, Issue:3

    Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adenylyl Cyclase Inhibitors; Astrocytoma; Bradykinin; Brain Neoplasms; Calcimycin; Calcium; Calmodulin; Colforsin; Cyclic AMP; Dopamine; Egtazic Acid; Humans; Hydroquinones; Inositol 1,4,5-Trisphosphate; Neoplasm Proteins; Pyrrolidinones; Rolipram; Signal Transduction; Tumor Cells, Cultured

1993
Changes in adenosine A1- and A2-receptor expression during adipose cell differentiation.
    Molecular and cellular endocrinology, 1996, Mar-01, Volume: 117, Issue:1

    Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adipose Tissue; Animals; Blotting, Northern; Cell Differentiation; Cells, Cultured; Cyclic AMP; Dexamethasone; Humans; Lipolysis; Mice; Phenylisopropyladenosine; Receptors, Purinergic P1

1996
Regulation of endothelial Na(+)-K(+)-ATPase activity by cAMP.
    Biochemical and biophysical research communications, 1998, Jan-06, Volume: 242, Issue:1

    Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Adenosine-5'-(N-ethylcarboxamide); Animals; Aorta; Biological Transport; Cesium; Cyclic AMP; Endothelium, Vascular; Iloprost; Nuclear Magnetic Resonance, Biomolecular; Potassium; Purinergic P1 Receptor Agonists; Receptors, Prostaglandin; Sodium-Potassium-Exchanging ATPase; Swine

1998
Adenosine signaling promotes neuronal, catecholaminergic differentiation of primary neural crest cells and CNS-derived CAD cells.
    Molecular and cellular neurosciences, 2005, Volume: 29, Issue:3

    Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Adenosine-5'-(N-ethylcarboxamide); Adrenal Medulla; Animals; Bone Morphogenetic Protein 2; Bone Morphogenetic Proteins; Catecholamines; Cell Differentiation; Cell Line; Cells, Cultured; Chromaffin Cells; Coturnix; Culture Media, Serum-Free; Cyclic AMP; Neural Crest; Neurons; Quinazolines; Receptor, Adenosine A2A; Receptor, Adenosine A2B; Signal Transduction; Sympathetic Nervous System; Transforming Growth Factor beta; Triazoles; Tyrosine 3-Monooxygenase

2005
An antagonistic interaction between A2B adenosine and D2 dopamine receptors modulates the function of rat carotid body chemoreceptor cells.
    Journal of neurochemistry, 2008, Volume: 107, Issue:5

    Topics: 1-Methyl-3-isobutylxanthine; Acetamides; Adenosine; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Adenosine-5'-(N-ethylcarboxamide); Animals; Caffeine; Carotid Body; Catecholamines; Chemoreceptor Cells; Cyclic AMP; Dopamine Agents; Dopamine D2 Receptor Antagonists; Dose-Response Relationship, Drug; Drug Interactions; Female; Male; Oxygen; Phenethylamines; Phosphodiesterase Inhibitors; Purines; Rats; Rats, Wistar; Receptor, Adenosine A2B; Receptors, Dopamine D2; Tritium; Vasodilator Agents

2008