Compounds > 1-methyl-3-isobutylxanthine

1-methyl-3-isobutylxanthine and 8-methoxymethyl-3-isobutyl-1-methylxanthine

1-methyl-3-isobutylxanthine has been researched along with 8-methoxymethyl-3-isobutyl-1-methylxanthine in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19901 (20.00)18.7374
1990's1 (20.00)18.2507
2000's2 (40.00)29.6817
2010's1 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ibay, AC; Martinson, EA; Schneller, SW; Wells, JN1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Kawasaki, T; Kobayashi, Y; Nakamura, H; Oki, Y; Shimizu, E; Yoshimi, T1
Ciruela, A; Clynes, MA; Cooper, DM; Goraya, TA; Masada, N; Willoughby, D1
Cheng, Q; Petkov, GV; Rovner, ES; Soder, RP; Xin, W1

Other Studies

5 other study(ies) available for 1-methyl-3-isobutylxanthine and 8-methoxymethyl-3-isobutyl-1-methylxanthine

ArticleYear
Inhibition of cyclic nucleotide phosphodiesterases from pig coronary artery by benzo-separated analogues of 3-isobutyl-1-methylxanthine.
    Journal of medicinal chemistry, 1986, Volume: 29, Issue:6

    Topics: 1-Methyl-3-isobutylxanthine; 2',3'-Cyclic-Nucleotide Phosphodiesterases; Coronary Vessels; Structure-Activity Relationship; Theophylline

1986
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
OPC-13013, a cyclic nucleotide phosphodiesterase type III, inhibitor, inhibits cell proliferation and transdifferentiation of cultured rat hepatic stellate cells.
    Life sciences, 1999, Volume: 64, Issue:23

    Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Actins; Animals; Cell Differentiation; Cell Division; Cells, Cultured; Cilostazol; Culture Media; Cyclic AMP; Desmin; Dose-Response Relationship, Drug; Isoenzymes; Liver; Male; Muscle, Smooth; Phosphodiesterase Inhibitors; Rats; Rats, Sprague-Dawley; Tetrazoles; Xanthines

1999
Kinetic properties of Ca2+/calmodulin-dependent phosphodiesterase isoforms dictate intracellular cAMP dynamics in response to elevation of cytosolic Ca2+.
    Cellular signalling, 2008, Volume: 20, Issue:2

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Calcium; Cell Extracts; Cell Line; Cyclic AMP; Cyclic Nucleotide Phosphodiesterases, Type 1; Cytosol; Enzyme Activation; Enzyme Inhibitors; Fluorescence Resonance Energy Transfer; Humans; Intracellular Space; Isoenzymes; Kinetics; Mice; Protein Transport; Rats; Subcellular Fractions; Xanthines

2008
Selective inhibition of phosphodiesterase 1 relaxes urinary bladder smooth muscle: role for ryanodine receptor-mediated BK channel activation.
    American journal of physiology. Cell physiology, 2012, Nov-15, Volume: 303, Issue:10

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Cells, Cultured; Cyclic AMP; Cyclic Nucleotide Phosphodiesterases, Type 1; Electric Stimulation; Gene Expression Regulation, Enzymologic; Guinea Pigs; Humans; Isoenzymes; Large-Conductance Calcium-Activated Potassium Channels; Male; Membrane Potentials; Muscle Relaxation; Muscle, Smooth; Patch-Clamp Techniques; Phosphodiesterase Inhibitors; Ryanodine Receptor Calcium Release Channel; Signal Transduction; Tissue Culture Techniques; Urinary Bladder; Xanthines

2012