1-methyl-3-isobutylxanthine and 8-bromocyclic gmp

1-methyl-3-isobutylxanthine has been researched along with 8-bromocyclic gmp in 107 studies

Research

Studies (107)

Timeframe	Studies, this research(%)	All Research%
pre-1990	27 (25.23)	18.7374
1990's	55 (51.40)	18.2507
2000's	19 (17.76)	29.6817
2010's	5 (4.67)	24.3611
2020's	1 (0.93)	2.80

Authors

Authors	Studies
Garbers, DL; Kopf, GS; Tubb, DJ	1
Khalifa-Zade, MCh; Kolesnikov, SS; Kosolapov, AV	1
Cramb, G; Gilkes, AF; Guild, SB; MacKay, KB	1
Mukhopadhyay, AK; Müller, D; Schumacher, H	1
Ache, BW; Michel, WC	1
Barnett, R; Blaufox, S; Nord, EP; Ortiz, PA; Ramsammy, L; Singer, S	1
Fukuda, A; Minami, T; Nabekura, J; Oomura, Y	1
Appel, RG	1
Garg, UC; Hassid, A	1
Schwarzschild, MA; Zigmond, RE	1
Das, S; Garepapaghi, M; Palmer, LG	1
Aronica, SM; Katzenellenbogen, BS	1
Wainwright, LK; Wainwright, SD	1
Hamet, P; Kuchel, O; Matusak, O	1
Darrow, B; Firestein, S; Shepherd, GM	1
Anderson, RJ; Breckon, R; Colston, D	1
Firestein, S; Shepherd, GM; Zufall, F	1
Fujita, N; Hayashi, H; Okada, N; Shibanaka, Y	1
Morton, DB; Truman, JW	1
Cassity, N; Martinez, JR	1
Laychock, SG	1
Brenner, BM; Seifter, JL; Silva, P; Zeidel, ML	1
Narahashi, T; Tsunoo, A	1
Gemignani, A; Marchi, M; Paudice, P; Raiteri, M	1
Brunswig, B; Budnik, LT; Mukhopadhyay, AK	1
Kreisberg, J; Kremer, S; Skorecki, K; Troyer, D	1
Berkowitz, AS; Preslock, JP; Wun, WS	1
Kirk, MD; Scheller, RH; Taussig, R	1
Alberts, P; Ogren, VR	1
Nakatani, K; Yau, KW	1
Anderson, RJ; Dillingham, MA	1
Iida, H; Page, E	1
Aghajanian, GK; Wang, YY	1
Benishin, CG; Pang, PK; Zeng, YY	1
Kotecha, N; Neild, TO	1
Hilf, G; Merz, WE	1
Bicknell, RJ; Schofield, JG	1
Alberts, P; Stjärne, L	1
Dowd, F; Jacobson, KL; Watson, EL	1
Cameron, CM; Rillema, JA	1
Barzen, KA; Lafferty, JL; Quissell, DO	1
Matsuura, M	1
Dartt, DA; Donowitz, M; Joshi, VJ; Mathieu, RS; Sharp, GW	1
Aloj, SM; Brandi, ML; Kohn, LD; Lopponi, A; Rotella, CM; Toccafondi, R	1
Giles, WR; Han, X; Shimoni, Y	1
Kennedy, MW; Kusel, JR; Proudfoot, L; Smith, HV	1
de Bessé, N; Lachaise, F; Saïdi, B; Sedlmeier, D; Webster, SG	1
McKenna, TM; Tao, S	1
Ashikaga, T; Kishi, Y; Numano, F; Watanabe, R	1
Angelini, GD; Newby, AC; Soyombo, AA	1
Ikeda, K; Sunose, H; Suzuki, M; Takasaka, T	1
Usachev, Y; Verkhratsky, A	1
Blum, G; Caramelo, C; Casado, S; Gallego, MJ; López Farré, A; Montón, M; Riesco, A	1
Fabczak, H; Fabczak, S; Song, PS; Tao, N	1
Chang, EB; De Jonge, HR; De Vente, J; Musch, MW; Vaandrager, AB; Wilson, KT	1
Grune, S; Jameson, HL; Myers, NC; Sawkat-Anwer, M	1
Bendig, J; Dzeja, C; Frings, S; Hagen, V; Kaupp, UB; Krause, E	1
Akamatsu, N; Inenaga, K; Yamashita, H	1
Davis, P; Gossell, M; Powell, N; Simon, OR	1
Duvilanski, BH; Lasaga, M; Pisera, D; Seilicovich, A; Zambruno, C	1
Pappano, AJ; Shirayama, T	1
Joyner, RW; Kumar, R; Namiki, T	1
Crilley, CT; Garcia, R	1
Greer, CA; Leinders-Zufall, T; Rand, MN; Shepherd, GM; Zufall, F	1
Gillard, ER; Grewal, RS; Khan, AM; Mouradi, B; Stanley, BG	1
Barman, SA	1
Kaneda, T; Nakajyo, S; Shimizu, K; Urakawa, N	1
Copenhagen, DR; Dixon, DB	1
Fabiano, C; Ientile, R; Macaione, S; Macaione, V; Pedale, S; Picciurro, V	1
Earm, YE; Han, J; Ho, WK; Kim, E; Lee, SH; Yoo, S	1
Azuma, H; Goto, M; Ishida, A; Kamikawatoko, S; Masuda, H; Tamaoki, S; Tokoro, T	1
Nawy, S; Stanton, PK; Wexler, EM	1
Kankaanranta, H; Kosonen, O; Lähde, M; Moilanen, E; Vuorinen, P; Ylitalo, P	1
Bełtowski, J; Górny, D; Marciniak, A	1
Beckers-Bleukx, G; Maréchal, G	1
Fyhrquist, F; Saijonmaa, O	1
Drummer, C; Gerzer, R; Herten, M; Lenz, W	1
Nawy, S	1
Murphy, ME	1
Pappano, AJ; Sakai, R; Shen, JB	1
Vaziri, ND; Wang, XQ	1
Corbalán, R; Felipo, V; Kosenko, E; Llansola, M; Montoliu, C	1
Borges, R; Brioso, MA; Machado, JD; Segura, F	1
Wang, WH	1
Ikeda, M; Kawase, T; Matsumoto, S; Nishikawa, T; Takahashi, T; Yoshida, S	1
Giovanni, A; Wirtz-Brugger, F	1
Christophersen, P; Jensen, BS; Olesen, SP; Schrøder, RL; Strøbaek, D	1
Joyner, RW; Kumar, R; Wagner, MB; Wang, Y	1
Nakatani, K; Yamada, H	1
Al-Hassani, M; Gupta, MP; Hart, CM; Natarajan, V; Ober, MD; Patterson, C	1
Derks, M; Kuwayama, H; Roelofs, J; Snippe, H; Van Haastert, PJ	1
Lutz, T; Riediger, T; Schmid, HA; Simon, E	1
Tsuchida, K; Watajima, H	1
Harayama, H; Kato, S	1
Bamba, T; Ding, WG; Matsuura, H; Shimizu, K; Shintani, Y	1
Caffrey, JL; Farias, M; Jackson, K; Johnson, M	1
Akerman, BL; Keegan, BP; North, WG; Péqueux, C	1
Canová, NK; Farghali, H; Kameníková, L; Kmonícková, E; Lincová, D	1
Prehm, P; Schulz, T; Schumacher, U	1
Mühlbauer, E; Peschke, E; Stumpf, I	1
Sosroseno, W; Sugiatno, E	1
Arendshorst, WJ; Fellner, SK	1
Choi, BK; Kots, AY; Martin, E; Mujoo, K; Murad, F; Nikonoff, LE; Sharin, VG; Sloan, C	1
Biel, M; Leinders-Zufall, T; Pyrski, M; Schmid, A; Zufall, F	1
Han, J; Lee, S; Xu, Z	1
Ando, M; Kobayashi, T; Matsumoto, T; Taguchi, K	1
Alvarez, DF; Annamdevula, N; Audia, JP; Britain, A; Dunbar, G; Hardy, KS; Housley, N; Leavesley, S; Renema, P; Rich, T; Spadafora, D	1

Other Studies

107 other study(ies) available for 1-methyl-3-isobutylxanthine and 8-bromocyclic gmp

Article	Year
Activation of sperm respiration by a low molecular weight egg factor and by 8-bromoguanosine 3',5'-monophosphate. The Journal of biological chemistry, 1979, Sep-10, Volume: 254, Issue:17 Topics: 1-Methyl-3-isobutylxanthine; Animals; Arachidonic Acids; Cyclic AMP; Cyclic GMP; Female; Kinetics; Male; Ovum; Oxygen Consumption; Peptides; Sea Urchins; Spermatozoa; Structure-Activity Relationship	1979
Photosensitivity of 8BrcGMP-induced conductance in ROS-excised patches. FEBS letters, 1992, Jul-06, Volume: 305, Issue:3 Topics: 1-Methyl-3-isobutylxanthine; Animals; Cyclic GMP; In Vitro Techniques; Light; Rod Cell Outer Segment; Signal Transduction; Xenopus laevis	1992
Atrial natriuretic peptide effects in AtT-20 pituitary tumour cells. Molecular and cellular endocrinology, 1992, Volume: 89, Issue:1-2 Topics: 1-Methyl-3-isobutylxanthine; Adrenocorticotropic Hormone; Animals; Atrial Natriuretic Factor; Calcium; Cell Membrane Permeability; Corticotropin-Releasing Hormone; Cyclic AMP; Cyclic GMP; Hypothalamo-Hypophyseal System; Mice; Nitroprusside; Pituitary Neoplasms; Receptors, Atrial Natriuretic Factor; Tumor Cells, Cultured	1992
Stimulation of testosterone production by atrial natriuretic peptide in isolated mouse Leydig cells results from a promiscuous activation of cyclic AMP-dependent protein kinase by cyclic GMP. Molecular and cellular endocrinology, 1992, Volume: 90, Issue:1 Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Atrial Natriuretic Factor; Cell-Free System; Cells, Cultured; Chorionic Gonadotropin; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Activation; Leydig Cells; Male; Mice; Peptide Fragments; Protein Kinases; Second Messenger Systems; Testosterone; Thionucleotides	1992
Cyclic nucleotides mediate an odor-evoked potassium conductance in lobster olfactory receptor cells. The Journal of neuroscience : the official journal of the Society for Neuroscience, 1992, Volume: 12, Issue:10 Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Animals; Colforsin; Cyclic AMP; Cyclic GMP; Electric Conductivity; Nephropidae; Odorants; Olfactory Pathways; Potassium; Signal Transduction	1992
Atrial natriuretic factor alters phospholipid metabolism in mesangial cells. The American journal of physiology, 1990, Volume: 258, Issue:1 Pt 1 Topics: 1-Methyl-3-isobutylxanthine; Angiotensin II; Animals; Arachidonic Acid; Arachidonic Acids; Atrial Natriuretic Factor; Calcimycin; Calcium; Cells, Cultured; Cyclic GMP; Glomerular Mesangium; Inositol; Inositol Phosphates; Kinetics; Male; Muscle, Smooth; Nitroprusside; Phosphatidylinositols; Phospholipids; Rats; Rats, Inbred Strains	1990
17 beta-estradiol depolarization of hypothalamic neurons is mediated by cyclic AMP. Brain research, 1990, Jun-11, Volume: 519, Issue:1-2 Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Calcium; Colforsin; Cyclic AMP; Cyclic GMP; Drug Implants; Electric Conductivity; Estradiol; Female; Guinea Pigs; Hypothalamus; Imidazoles; Membrane Potentials; Neurons; Ovariectomy; Potassium; Theophylline	1990
Mechanism of atrial natriuretic factor-induced inhibition of rat mesangial cell mitogenesis. The American journal of physiology, 1990, Volume: 259, Issue:3 Pt 1 Topics: 1-Methyl-3-isobutylxanthine; Animals; Atrial Natriuretic Factor; Cell Division; Cell Line; Cells, Cultured; Cyclic GMP; DNA Replication; Dose-Response Relationship, Drug; Glomerular Mesangium; Kinetics; Male; Mice; Nitroprusside; Rats; Rats, Inbred Strains; Thymidine	1990
Nitric oxide decreases cytosolic free calcium in Balb/c 3T3 fibroblasts by a cyclic GMP-independent mechanism. The Journal of biological chemistry, 1991, Jan-05, Volume: 266, Issue:1 Topics: 1-Methyl-3-isobutylxanthine; Animals; Calcium; Cell Line; Cyclic AMP; Cyclic GMP; Cytosol; Fibroblasts; Isosorbide Dinitrate; Kinetics; Mice; Mice, Inbred BALB C; Nitric Oxide; Penicillamine; S-Nitroso-N-Acetylpenicillamine; Vasodilator Agents	1991
Effects of peptides of the secretin-glucagon family and cyclic nucleotides on tyrosine hydroxylase activity in sympathetic nerve endings. Journal of neurochemistry, 1991, Volume: 56, Issue:2 Topics: 1-Methyl-3-isobutylxanthine; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Colforsin; Cyclic AMP; Cyclic GMP; Drug Synergism; Heart Ventricles; Male; Nerve Endings; Nitroprusside; Protein Kinase C; Rats; Rats, Inbred Strains; Second Messenger Systems; Secretin; Sympathetic Nervous System; Tyrosine 3-Monooxygenase; Vasoactive Intestinal Peptide	1991
Stimulation by cGMP of apical Na channels and cation channels in toad urinary bladder. The American journal of physiology, 1991, Volume: 260, Issue:2 Pt 1 Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Bufo marinus; Cell Membrane; Cyclic GMP; Electric Conductivity; In Vitro Techniques; Ion Channels; Kinetics; Membrane Potentials; Sodium; Sodium Channels; Urinary Bladder	1991
Progesterone receptor regulation in uterine cells: stimulation by estrogen, cyclic adenosine 3',5'-monophosphate, and insulin-like growth factor I and suppression by antiestrogens and protein kinase inhibitors. Endocrinology, 1991, Volume: 128, Issue:4 Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Blotting, Western; Cells, Cultured; Cholera Toxin; Cyclic AMP; Cyclic GMP; Estradiol; Estrogen Antagonists; Female; Insulin-Like Growth Factor I; Kinetics; Promegestone; Protein Kinase Inhibitors; Rats; Rats, Inbred Strains; Receptors, Progesterone; Uterus	1991
Inhibition of the chick pineal rhythm in rate of thymidine incorporation by cyclic AMP. Journal of neurochemistry, 1991, Volume: 56, Issue:5 Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Chickens; Colforsin; Cyclic AMP; Cyclic GMP; Periodicity; Phosphodiesterase Inhibitors; Pineal Gland; Thymidine	1991
Effect of atrial natriuretic factor and 8-bromo cyclic guanosine 3':5'-monophosphate on [3H]acetylcholine outflow from myenteric-plexus longitudinal muscle of the guinea pig. The Journal of pharmacology and experimental therapeutics, 1991, Volume: 257, Issue:1 Topics: 1-Methyl-3-isobutylxanthine; Acetylcholine; Animals; Atrial Natriuretic Factor; Cyclic GMP; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Myenteric Plexus; Tritium	1991
Activation of the sensory current in salamander olfactory receptor neurons depends on a G protein-mediated cAMP second messenger system. Neuron, 1991, Volume: 6, Issue:5 Topics: 1-Methyl-3-isobutylxanthine; Animals; Cyclic AMP; Cyclic GMP; Electrophysiology; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Hydrolysis; Neurons; Odorants; Phosphoric Diester Hydrolases; Protein Kinases; Second Messenger Systems; Sensory Receptor Cells; Smell; Urodela	1991
Regulation by forskolin of cyclic AMP phosphodiesterase and protein kinase C activity in LLC-PK1 cells. The Biochemical journal, 1991, Oct-01, Volume: 279 ( Pt 1) Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Alkaloids; Animals; Cells, Cultured; Colforsin; Cyclic GMP; Galactose; Macaca mulatta; Pregnenolone; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate	1991
Single odor-sensitive channels in olfactory receptor neurons are also gated by cyclic nucleotides. The Journal of neuroscience : the official journal of the Society for Neuroscience, 1991, Volume: 11, Issue:11 Topics: 1-Methyl-3-isobutylxanthine; Animals; Cyclic AMP; Cyclic GMP; Ion Channel Gating; Ion Channels; Neurons, Afferent; Nucleotides, Cyclic; Odorants; Olfactory Pathways; Sensory Receptor Cells; Stimulation, Chemical	1991
The crucial role of cyclic GMP in the eclosion hormone mediated signal transduction in the silkworm metamorphoses. Biochemical and biophysical research communications, 1991, Oct-31, Volume: 180, Issue:2 Topics: 1-Methyl-3-isobutylxanthine; Animals; Bombyx; Cyclic GMP; Dose-Response Relationship, Drug; Insect Hormones; Metamorphosis, Biological; Moths; Recombinant Proteins; Second Messenger Systems; Signal Transduction	1991
Steroid regulation of the peptide-mediated increase in cyclic GMP in the nervous system of the hawkmoth, Manduca sexta. Journal of comparative physiology. A, Sensory, neural, and behavioral physiology, 1985, Volume: 157, Issue:4 Topics: 1-Methyl-3-isobutylxanthine; Animals; Cyclic GMP; Ganglia; Insect Hormones; Lepidoptera; Moths; Theophylline	1985
Effects of cyclic nucleotide derivatives on acetylcholine-induced secretion from isolated, perfused rat submandibular salivary glands. Archives of oral biology, 1986, Volume: 31, Issue:7 Topics: 1-Methyl-3-isobutylxanthine; Acetylcholine; Animals; Bucladesine; Cyclic GMP; Isoproterenol; Male; Nucleotides, Cyclic; Rats; Rats, Inbred Strains; Saliva; Submandibular Gland; Theophylline	1986
Effects of guanosine 3',5'-monophosphate on glucose utilization in isolated islets of Langerhans. Endocrinology, 1987, Volume: 120, Issue:2 Topics: 1-Methyl-3-isobutylxanthine; Acetylglucosamine; Animals; Cyclic GMP; Cycloheximide; Dibutyryl Cyclic GMP; Glucose; In Vitro Techniques; Islets of Langerhans; Kinetics; Male; Mannitol; Methylnitronitrosoguanidine; Rats; Rats, Inbred Strains	1987
cGMP mediates effects of atrial peptides on medullary collecting duct cells. The American journal of physiology, 1987, Volume: 252, Issue:3 Pt 2 Topics: 1-Methyl-3-isobutylxanthine; Animals; Atrial Natriuretic Factor; Cyclic GMP; Dose-Response Relationship, Drug; Kidney Tubules; Kidney Tubules, Collecting; Microscopy, Electron; Nitroprusside; Oxygen Consumption; Rabbits; Swine	1987
Cyclic nucleotide potentiation of muscarinic responses in neuroblastoma cells. Brain research, 1987, Mar-24, Volume: 407, Issue:1 Topics: 1-Methyl-3-isobutylxanthine; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Acetylcholine; Adenine; Adenosine; Animals; Bucladesine; Cell Line; Cyclic AMP; Cyclic GMP; Dopamine; Membrane Potentials; Neurons; Receptors, Muscarinic	1987
Is the muscarinic receptor that mediates potentiation of dopamine release negatively coupled to the cyclic GMP system? Journal of neuroscience research, 1987, Volume: 17, Issue:2 Topics: 1-Methyl-3-isobutylxanthine; Acetylcholine; Animals; Corpus Striatum; Cyclic GMP; Dopamine; Frontal Lobe; Potassium Chloride; Rats; Rats, Inbred Strains; Receptors, Muscarinic	1987
Atrial natriuretic factor stimulates luteal guanylate cyclase. Regulatory peptides, 1987, Volume: 19, Issue:1-2 Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Atrial Natriuretic Factor; Chlorides; Chorionic Gonadotropin; Corpus Luteum; Cyclic AMP; Cyclic GMP; Female; Guanylate Cyclase; In Vitro Techniques; Kinetics; Magnesium; Magnesium Chloride; Manganese; Manganese Compounds; Progesterone; Rats	1987
Interaction of atrial natriuretic peptide-stimulated guanylate cyclase and vasopressin-stimulated calcium signaling pathways in the glomerular mesangial cell. Archives of biochemistry and biophysics, 1988, Feb-01, Volume: 260, Issue:2 Topics: 1-Methyl-3-isobutylxanthine; Animals; Atrial Natriuretic Factor; Calcium; Cells, Cultured; Cyclic GMP; Cytosol; Fluorescent Dyes; Guanylate Cyclase; Indoles; Inositol Phosphates; Kidney Glomerulus; Rats; Rats, Inbred Strains; Vasopressins	1988
Differences in the cyclic nucleotide mediation of luteinizing hormone-releasing hormone action on the rat and hamster anterior pituitary gland. Molecular and cellular endocrinology, 1988, Volume: 55, Issue:2-3 Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Cricetinae; Cyclic GMP; Follicle Stimulating Hormone; Gonadotropin-Releasing Hormone; In Vitro Techniques; Kinetics; Luteinizing Hormone; Male; Mesocricetus; Pituitary Gland, Anterior; Rats; Species Specificity; Theophylline	1988
Egg-laying hormone, serotonin, and cyclic nucleotide modulation of ionic currents in the identified motoneuron B16 of Aplysia. The Journal of neuroscience : the official journal of the Society for Neuroscience, 1988, Volume: 8, Issue:4 Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Aplysia; Colforsin; Cyclic GMP; Electrophysiology; Invertebrate Hormones; Membrane Potentials; Motor Neurons; Serotonin	1988
Interaction of forskolin with the effect of atropine on [3H]acetylcholine secretion in guinea-pig ileum myenteric plexus. The Journal of physiology, 1988, Volume: 395 Topics: 1-Methyl-3-isobutylxanthine; 4-Aminopyridine; 8-Bromo Cyclic Adenosine Monophosphate; Acetylcholine; Aminopyridines; Animals; Atropine; Colforsin; Cyclic GMP; Drug Interactions; Guinea Pigs; Ileum; In Vitro Techniques; Myenteric Plexus; Neuromuscular Junction	1988
Guanosine 3',5'-cyclic monophosphate-activated conductance studied in a truncated rod outer segment of the toad. The Journal of physiology, 1988, Volume: 395 Topics: 1-Methyl-3-isobutylxanthine; Action Potentials; Adenosine Triphosphate; Animals; Bufo marinus; Cyclic GMP; Dose-Response Relationship, Drug; Guanosine Triphosphate; In Vitro Techniques; Light; Photoreceptor Cells; Rod Cell Outer Segment; Time Factors	1988
Cyclic guanosine monophosphate increases hydraulic conductivity in rabbit and rat CCT. The American journal of physiology, 1988, Volume: 255, Issue:5 Pt 2 Topics: 1-Methyl-3-isobutylxanthine; Animals; Arginine Vasopressin; Cyclic GMP; Hemin; In Vitro Techniques; Kidney Tubules; Kidney Tubules, Collecting; Nitroprusside; Osmolar Concentration; Rabbits; Rats; Rats, Inbred Strains; Water-Electrolyte Balance	1988
Inhibition of atrial natriuretic peptide secretion by forskolin in noncontracting cultured atrial myocytes. Biochemical and biophysical research communications, 1988, Nov-30, Volume: 157, Issue:1 Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Atrial Natriuretic Factor; Bucladesine; Calcium; Cells, Cultured; Colforsin; Cyclic GMP; Egtazic Acid; Muscle Contraction; Muscle, Smooth, Vascular; Protein Kinase C; Ryanodine; Sarcoplasmic Reticulum; Secretory Rate; Tetradecanoylphorbol Acetate	1988
Excitation of locus coeruleus neurons by an adenosine 3',5'-cyclic monophosphate-activated inward current: extracellular and intracellular studies in rat brain slices. Synapse (New York, N.Y.), 1987, Volume: 1, Issue:5 Topics: 1-Methyl-3-isobutylxanthine; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Colforsin; Cyclic AMP; Cyclic GMP; In Vitro Techniques; Locus Coeruleus; Male; Membrane Potentials; Neurons; Rats; Reference Values; Theophylline	1987
Guanine nucleotide binding proteins may modulate gating of calcium channels in vascular smooth muscle. I. Studies with fluoride. The Journal of pharmacology and experimental therapeutics, 1989, Volume: 250, Issue:1 Topics: 1-Methyl-3-isobutylxanthine; Animals; Arginine Vasopressin; Arteries; Bucladesine; Calcium; Calcium Channels; Colforsin; Cyclic AMP; Cyclic GMP; GTP-Binding Proteins; In Vitro Techniques; Inositol Phosphates; Kinetics; Male; Muscle, Smooth, Vascular; Nifedipine; Potassium Chloride; Rats; Rats, Inbred Strains; Sodium Fluoride; Vasoconstriction; Verapamil	1989
A study of the phasic response of arterioles of the guinea pig small intestine to prolonged exposure to norepinephrine. Microvascular research, 1989, Volume: 38, Issue:2 Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Arterioles; Clonidine; Colforsin; Cyclic GMP; Dose-Response Relationship, Drug; Guinea Pigs; Intestine, Small; Isoproterenol; Membrane Potentials; Norepinephrine; Oxidation-Reduction; Propranolol; Temperature; Theophylline; Vasoconstriction; Yohimbine	1989
Influence of cyclic nucleotides on receptor binding, immunological activity, and microheterogeneity of human choriogonadotropin synthesized in placental tissue culture. Molecular and cellular endocrinology, 1985, Volume: 39, Issue:2 Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Chorionic Gonadotropin; Culture Techniques; Cyclic AMP; Cyclic GMP; Female; Humans; Isoelectric Focusing; Leydig Cells; Male; Mice; Nucleotides, Cyclic; Placenta; Pregnancy; Radioimmunoassay; Receptors, Cell Surface; Receptors, LH; Testosterone	1985
Role of cyclic nucleotides in the inhibition of growth-hormone secretion by somatostatin. Molecular and cellular endocrinology, 1981, Volume: 22, Issue:1 Topics: 1-Methyl-3-isobutylxanthine; Animals; Bucladesine; Cattle; Cholera Toxin; Cyclic AMP; Cyclic GMP; Female; Growth Hormone; Male; Pituitary Gland, Anterior; Somatostatin	1981
Secretion of 3H-acetylcholine from guinea-pig ileum myenteric plexus is enhanced by 8-Br adenosine 3', 5'-cyclic monophosphate but not changed by 8-Br guanosine 3', 5'-cyclic monophosphate. Acta physiologica Scandinavica, 1982, Volume: 115, Issue:2 Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Acetylcholine; Animals; Atropine; Cyclic AMP; Cyclic GMP; Electric Stimulation; Guinea Pigs; Ileum; Receptors, Cholinergic	1982
Does cyclic GMP mediate amylase release from mouse parotid acini? Life sciences, 1982, Nov-08, Volume: 31, Issue:19 Topics: 1-Methyl-3-isobutylxanthine; Amylases; Animals; Azides; Bucladesine; Carbachol; Cyclic GMP; Hydroxylamines; Mice; Nitroprusside; Parotid Gland; Sodium Azide	1982
Effects of cyclic nucleotides on lipid biosynthesis in mouse mammary gland explants. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1983, Volume: 173, Issue:3 Topics: 1-Methyl-3-isobutylxanthine; Acetates; Animals; Bucladesine; Cyclic GMP; Dibutyryl Cyclic GMP; Female; Lipids; Mammary Glands, Animal; Mice; Pregnancy; Prolactin	1983
Evidence against a role for guanosine 3',5'-cyclic monophosphate in rat submandibular salivary gland potassium release. Archives of oral biology, 1983, Volume: 28, Issue:11 Topics: 1-Methyl-3-isobutylxanthine; Animals; Cyclic GMP; Norepinephrine; Parasympathomimetics; Potassium; Rats; Rats, Inbred Strains; Submandibular Gland; Sympathomimetics	1983
Relaxation of Mytilus catch muscle by 8-bromo-cyclic GMP and related compounds. Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology, 1984, Volume: 78, Issue:1 Topics: 1-Methyl-3-isobutylxanthine; Acetylcholine; Animals; Bivalvia; Cyclic GMP; Egtazic Acid; Electric Stimulation; In Vitro Techniques; Mersalyl; Muscle Contraction; Muscle Relaxation; Potassium Chloride; Serotonin	1984
Cyclic nucleotide-dependent enzyme secretion in the rat lacrimal gland. The Journal of physiology, 1984, Volume: 352 Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Calcium; Carbachol; Cardiotonic Agents; Colforsin; Cyclic GMP; Diterpenes; In Vitro Techniques; Isoenzymes; Lacrimal Apparatus; Male; Peroxidase; Peroxidases; Rats; Rats, Inbred Strains; Stimulation, Chemical; Time Factors	1984
Forskolin perturbs cGMP as well as cAMP levels in human thyroid cells. Acta endocrinologica, 1984, Volume: 107, Issue:2 Topics: 1-Methyl-3-isobutylxanthine; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic GMP; Diterpenes; Humans; Phosphodiesterase Inhibitors; Thyroid Gland; Thyrotropin	1984
A cellular mechanism for nitric oxide-mediated cholinergic control of mammalian heart rate. The Journal of general physiology, 1995, Volume: 106, Issue:1 Topics: 1-Methyl-3-isobutylxanthine; Aminoquinolines; Animals; Arginine; Carbachol; Cardiotonic Agents; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Enzyme Inhibitors; GTP-Binding Proteins; Guanylate Cyclase; Heart Rate; Isoproterenol; Methylene Blue; Molsidomine; Muscarinic Agonists; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Platelet Aggregation Inhibitors; Rabbits; Receptors, Cholinergic; Receptors, Muscarinic; Sinoatrial Node; Thionucleotides	1995
External stimuli and intracellular signalling in the modification of the nematode surface during transition to the mammalian host environment. Parasitology, 1993, Volume: 107 ( Pt 5) Topics: 1-Methyl-3-isobutylxanthine; Aedes; Animals; Brugia; Calcimycin; Cyclic AMP; Cyclic GMP; Dipetalonema; Gallic Acid; Hydrogen-Ion Concentration; Larva; Mammals; Nematoda; Nicardipine; Nippostrongylus; Nitroprusside; Protein Kinase Inhibitors; Signal Transduction; Sulfonamides; Trichinella	1993
Involvement of cAMP and cGMP in the mode of action of molt-inhibiting hormone (MIH) a neuropeptide which inhibits steroidogenesis in a crab. Molecular and cellular endocrinology, 1994, Volume: 102, Issue:1-2 Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Brachyura; Bucladesine; Colforsin; Cyclic AMP; Cyclic GMP; Dibutyryl Cyclic GMP; Dose-Response Relationship, Drug; Ecdysone; Invertebrate Hormones	1994
In vitro endotoxin exposure induces contractile dysfunction in adult rat cardiac myocytes. The American journal of physiology, 1994, Volume: 267, Issue:5 Pt 2 Topics: 1-Methyl-3-isobutylxanthine; Animals; Arginine; Cell Survival; Cells, Cultured; Citrulline; Cyclic GMP; Dactinomycin; Electric Stimulation; Endotoxins; Heart; Kinetics; Male; Myocardial Contraction; Myocardium; NG-Nitroarginine Methyl Ester; Nitroprusside; Rats; Rats, Sprague-Dawley; Time Factors	1994
Atrial natriuretic peptide reduces cyclic AMP by activating cyclic GMP-stimulated phosphodiesterase in vascular endothelial cells. Journal of cardiovascular pharmacology, 1994, Volume: 24, Issue:3 Topics: 1-Methyl-3-isobutylxanthine; Adenine; Adenylyl Cyclases; Animals; Aorta; Atrial Natriuretic Factor; Cattle; Cells, Cultured; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Drug Interactions; Endothelium, Vascular; Isoenzymes; Isoproterenol; Isoquinolines; Nitroprusside; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Tetrahydroisoquinolines	1994
Neointima formation is promoted by surgical preparation and inhibited by cyclic nucleotides in human saphenous vein organ cultures. The Journal of thoracic and cardiovascular surgery, 1995, Volume: 109, Issue:1 Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Adenosine Triphosphate; Adult; Aged; Cell Division; Cyclic GMP; Female; Humans; Male; Middle Aged; Muscle, Smooth, Vascular; Organ Culture Techniques; Saphenous Vein; Tunica Intima	1995
Voltage-activated K channel in luminal membrane of marginal cells of stria vascularis dissected from guinea pig. Hearing research, 1994, Volume: 80, Issue:1 Topics: 1-Methyl-3-isobutylxanthine; Animals; Bucladesine; Calcium; Colforsin; Cyclic AMP; Cyclic GMP; Cytoplasm; Electric Stimulation; Electrophysiology; Gluconates; Guinea Pigs; Membrane Potentials; Patch-Clamp Techniques; Potassium Channels; Sodium Chloride; Stria Vascularis	1994
IBMX induces calcium release from intracellular stores in rat sensory neurones. Cell calcium, 1995, Volume: 17, Issue:3 Topics: 1-Methyl-3-isobutylxanthine; Animals; Animals, Newborn; Biological Transport; Bucladesine; Caffeine; Calcium; Cell Compartmentation; Colforsin; Cyclic GMP; Dibutyryl Cyclic GMP; Endoplasmic Reticulum; Ganglia, Spinal; Neurons, Afferent; Rats; Theophylline	1995
Nitric oxide-generating system as an autocrine mechanism in human polymorphonuclear leucocytes. The Biochemical journal, 1993, Jun-15, Volume: 292 ( Pt 3) Topics: 1-Methyl-3-isobutylxanthine; Arginine; Biological Transport; Citrulline; Cyclic GMP; Endothelins; Humans; In Vitro Techniques; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Nitric Oxide; Nitroprusside; omega-N-Methylarginine	1993
Photosensory transduction in ciliates. IV. Modulation of the photomovement response of Blepharisma japonicum by cGMP. Photochemistry and photobiology, 1993, Volume: 57, Issue:5 Topics: 1-Methyl-3-isobutylxanthine; Aminoquinolines; Animals; Cell Movement; Cholera Toxin; Ciliophora; Cyclic GMP; Dibutyryl Cyclic GMP; Light; Pertussis Toxin; Signal Transduction; Virulence Factors, Bordetella	1993
Production and localization of cGMP and PGE2 in nitroprusside-stimulated rat colonic ion transport. The American journal of physiology, 1996, Volume: 270, Issue:3 Pt 1 Topics: 1-Methyl-3-isobutylxanthine; Analysis of Variance; Animals; Biological Transport; Bradykinin; Captopril; Colon; Cyclic GMP; Dihydrolipoamide Dehydrogenase; Dinoprostone; In Vitro Techniques; Intestinal Mucosa; Ions; Models, Biological; Nitric Oxide Synthase; Nitroprusside; Rats; Rats, Sprague-Dawley; Tetrodotoxin; Vasodilator Agents	1996
cGMP stimulates bile acid-independent bile formation and biliary bicarbonate excretion. The American journal of physiology, 1996, Volume: 270, Issue:3 Pt 1 Topics: 1-Methyl-3-isobutylxanthine; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Amiloride; Animals; Arginine Vasopressin; Bicarbonates; Bile; Bile Acids and Salts; Calcium; Cells, Cultured; Choline; Cyclic AMP; Cyclic GMP; Glutathione; Hydrogen-Ion Concentration; In Vitro Techniques; Kinetics; Liver; Male; Oxygen Consumption; Rats; Rats, Wistar; Taurocholic Acid; Thionucleotides; Ursodeoxycholic Acid	1996
Caged compounds of hydrolysis-resistant analogues of cAMP and cGMP: synthesis and application to cyclic nucleotide-gated channels. Biochemistry, 1996, Jun-18, Volume: 35, Issue:24 Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Cattle; Cell Line; Cyclic AMP; Cyclic GMP; Humans; Indicators and Reagents; Ion Channel Gating; Ion Channels; Kidney; Kinetics; Magnetic Resonance Spectroscopy; Neurons, Afferent; Olfactory Pathways; Photolysis; Signal Transduction; Spectrophotometry; Stereoisomerism; Ultraviolet Rays	1996
Inhibitory effects of natriuretic peptides on vasopressin neurons mediated through cGMP and cGMP-dependent protein kinase in vitro. Journal of neuroendocrinology, 1993, Volume: 5, Issue:5 Topics: 1-Methyl-3-isobutylxanthine; Animals; Atrial Natriuretic Factor; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Electrophysiology; Enzyme Inhibitors; Isoquinolines; Male; Membrane Potentials; Natriuretic Peptide, Brain; Nerve Tissue Proteins; Neurons; Phosphodiesterase Inhibitors; Phthalazines; Rats; Rats, Wistar; Second Messenger Systems; Supraoptic Nucleus; Vasopressins	1993
Evidence that guanylate cyclase is involved in modulating the resting tension and neurally-induced contraction of the guinea pig tracheal muscle. The West Indian medical journal, 1996, Volume: 45, Issue:3 Topics: 1-Methyl-3-isobutylxanthine; Animals; Cyclic GMP; Electric Stimulation; Guanylate Cyclase; Guinea Pigs; Male; Methylene Blue; Muscle Contraction; Muscle Relaxation; Nitroprusside; Phosphodiesterase Inhibitors; Rest; Trachea	1996
Role of nitric oxide/cyclic GMP pathway in the inhibitory effect of GABA and dopamine on prolactin release. Journal of neuroendocrinology, 1996, Volume: 8, Issue:12 Topics: 1-Methyl-3-isobutylxanthine; Aminoquinolines; Animals; Cyclic AMP; Cyclic GMP; Dopamine; Enzyme Inhibitors; gamma-Aminobutyric Acid; Hemoglobins; Male; Neurotransmitter Agents; NG-Nitroarginine Methyl Ester; Nitric Oxide; Phosphodiesterase Inhibitors; Pituitary Gland; Prolactin; Rats; Rats, Wistar	1996
Biphasic effects of intrapipette cyclic guanosine monophosphate on L-type calcium current and contraction of guinea pig ventricular myocytes. The Journal of pharmacology and experimental therapeutics, 1996, Volume: 279, Issue:3 Topics: 1-Methyl-3-isobutylxanthine; Animals; Calcium; Calcium Channels; Cyclic GMP; Guinea Pigs; Heart Ventricles; In Vitro Techniques; Isoproterenol; Myocardial Contraction; Ventricular Function	1996
Effects of cGMP on L-type calcium current of adult and newborn rabbit ventricular cells. Cardiovascular research, 1997, Volume: 33, Issue:3 Topics: 1-Methyl-3-isobutylxanthine; Alkaloids; Aminoquinolines; Animals; Animals, Newborn; Calcium; Calcium Channels; Carbazoles; Cells, Cultured; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Female; Glutathione; Guanylate Cyclase; Indoles; Male; Methylene Blue; Myocardium; Nitroso Compounds; Patch-Clamp Techniques; Phosphodiesterase Inhibitors; Protein Kinase Inhibitors; Rabbits; S-Nitrosoglutathione; Thionucleotides; Time Factors	1997
Effects of atrial natriuretic factor on glucose metabolism in isolated adipocytes. Regulatory peptides, 1997, Jan-29, Volume: 68, Issue:2 Topics: 1-Methyl-3-isobutylxanthine; Adipocytes; Animals; Atrial Natriuretic Factor; Carbon Dioxide; Cell Count; Cyclic AMP; Cyclic GMP; Glucose; Guanylate Cyclase; Insulin; Isoproterenol; Lipid Metabolism; Male; Natriuretic Peptide, C-Type; Peptide Fragments; Proteins; Rats; Rats, Sprague-Dawley; Receptors, Atrial Natriuretic Factor	1997
Calcium entry through cyclic nucleotide-gated channels in individual cilia of olfactory receptor cells: spatiotemporal dynamics. The Journal of neuroscience : the official journal of the Society for Neuroscience, 1997, Jun-01, Volume: 17, Issue:11 Topics: 1-Methyl-3-isobutylxanthine; Adaptation, Physiological; Ambystoma; Aminoquinolines; Aniline Compounds; Animals; Calcium; Cilia; Cyclic AMP; Cyclic GMP; Electric Stimulation; Electrophysiology; Enzyme Inhibitors; Epithelial Cells; Fluorescent Dyes; GTP-Binding Proteins; Ion Channel Gating; Membrane Potentials; Microscopy, Confocal; Olfactory Receptor Neurons; Phosphodiesterase Inhibitors; Potassium; Second Messenger Systems; Time Factors; Xanthenes	1997
Stimulation of eating by the second messenger cAMP in the perifornical and lateral hypothalamus. The American journal of physiology, 1997, Volume: 273, Issue:1 Pt 2 Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Colforsin; Cyclic AMP; Cyclic GMP; Diterpenes; Eating; Hypothalamic Area, Lateral; Male; Neurons; Paraventricular Hypothalamic Nucleus; Rats; Rats, Sprague-Dawley; Second Messenger Systems; Stereotaxic Techniques; Thalamus	1997
Role of calcium-activated potassium channels and cyclic nucleotides on pulmonary vasoreactivity to serotonin. The American journal of physiology, 1997, Volume: 273, Issue:1 Pt 1 Topics: 1-Methyl-3-isobutylxanthine; Animals; Bucladesine; Calcium; Cyclic AMP; Cyclic GMP; Dogs; Female; In Vitro Techniques; Large-Conductance Calcium-Activated Potassium Channels; Lung; Male; Potassium Channels; Potassium Channels, Calcium-Activated; Pulmonary Circulation; Second Messenger Systems; Serotonin; Tetraethylammonium; Tetraethylammonium Compounds; Vascular Resistance	1997
Effects of various selective phosphodiesterase inhibitors on muscle contractility in guinea pig ileal longitudinal smooth muscle. Japanese journal of pharmacology, 1997, Volume: 75, Issue:1 Topics: 1-Methyl-3-isobutylxanthine; Animals; Calcium; Carbachol; Cell Membrane Permeability; Cyclic AMP; Cyclic GMP; Detergents; Guinea Pigs; Ileum; Male; Muscle Contraction; Muscle, Smooth; Nitroprusside; Octoxynol; Phosphodiesterase Inhibitors; Potassium; Purinones; Type C Phospholipases; Vasodilator Agents	1997
Metabotropic glutamate receptor-mediated suppression of an inward rectifier current is linked via a cGMP cascade. The Journal of neuroscience : the official journal of the Society for Neuroscience, 1997, Dec-01, Volume: 17, Issue:23 Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Adenosine Triphosphate; Aminobutyrates; Animals; Atrial Natriuretic Factor; Benzoates; Cyclic GMP; Enzyme Inhibitors; Glutamic Acid; Glycine; Ictaluridae; Ion Channel Gating; Isoquinolines; Models, Neurological; Patch-Clamp Techniques; Photoreceptor Cells; Potassium Channels; Receptors, Metabotropic Glutamate; Second Messenger Systems; Thionucleotides	1997
Nitric oxide mediates NMDA-evoked [3H]GABA release from chick retina cells. FEBS letters, 1997, Nov-17, Volume: 417, Issue:3 Topics: 1-Methyl-3-isobutylxanthine; Animals; Cell Differentiation; Cells, Cultured; Chick Embryo; Cyclic GMP; Dizocilpine Maleate; gamma-Aminobutyric Acid; Isoquinolines; N-Methylaspartate; Nitric Oxide; Nitroarginine; Nitrogen Oxides; Purinones; Receptors, N-Methyl-D-Aspartate; Retina; Spermine; Tritium	1997
cGMP facilitates calcium current via cGMP-dependent protein kinase in isolated rabbit ventricular myocytes. Pflugers Archiv : European journal of physiology, 1998, Volume: 435, Issue:3 Topics: 1-Methyl-3-isobutylxanthine; Adrenergic beta-Agonists; Animals; Calcium Channels; Colforsin; Cyclic GMP; Electric Conductivity; Enzyme Inhibitors; Female; Heart; Isoproterenol; Male; Membrane Potentials; Protein Kinases; Rabbits; Thionucleotides	1998
Nitric oxide-induced ciliary muscle relaxation during contraction with endothelin-1 is mediated through elevation of cyclic GMP. Current eye research, 1997, Volume: 16, Issue:12 Topics: 1-Methyl-3-isobutylxanthine; Animals; Cattle; Ciliary Body; Cyclic GMP; Drug Combinations; Endothelin-1; Guanylate Cyclase; In Vitro Techniques; Methylene Blue; Muscle Contraction; Muscle Relaxation; Nitric Oxide; Nitroprusside; Phosphodiesterase Inhibitors	1997
Nitric oxide depresses GABAA receptor function via coactivation of cGMP-dependent kinase and phosphodiesterase. The Journal of neuroscience : the official journal of the Society for Neuroscience, 1998, Apr-01, Volume: 18, Issue:7 Topics: 1-Methyl-3-isobutylxanthine; Animals; Cells, Cultured; Cyclic GMP; Cyclic GMP-Dependent Protein Kinase Type I; Cyclic GMP-Dependent Protein Kinases; Cyclic IMP; Enzyme Activation; Enzyme Inhibitors; Nitric Oxide; Nitroprusside; Oligopeptides; Oxadiazoles; Penicillamine; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, GABA-A; Retina; Sulfhydryl Reagents	1998
Nitric oxide-releasing oxatriazole derivatives inhibit human lymphocyte proliferation by a cyclic GMP-independent mechanism. The Journal of pharmacology and experimental therapeutics, 1998, Volume: 286, Issue:1 Topics: 1-Methyl-3-isobutylxanthine; Cyclic GMP; Guanylate Cyclase; Humans; Lymphocyte Activation; Nitric Oxide; Triazoles	1998
The mechanism of Na+, K+-ATPase inhibition by atrial natriuretic factor in rat renal medulla. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 1998, Volume: 49, Issue:2 Topics: 1-Methyl-3-isobutylxanthine; Alkaloids; Animals; Atrial Natriuretic Factor; Carbazoles; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Enzyme Inhibitors; Indoles; Kidney Medulla; Male; Papaverine; Phosphodiesterase Inhibitors; Rats; Rats, Wistar; Sodium-Potassium-Exchanging ATPase	1998
Effect of nitric oxide on the maximal velocity of shortening of a mouse skeletal muscle. Pflugers Archiv : European journal of physiology, 1998, Volume: 436, Issue:6 Topics: 1-Methyl-3-isobutylxanthine; Aminoquinolines; Animals; Biomechanical Phenomena; Cyclic GMP; Enzyme Inhibitors; Guanylate Cyclase; Male; Mice; Mice, Inbred C57BL; Muscle Contraction; Muscle, Skeletal; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroarginine; Nitroprusside; Penicillamine; Phosphodiesterase Inhibitors; Stereoisomerism	1998
Upregulation of angiotensin converting enzyme by atrial natriuretic peptide and cyclic GMP in human endothelial cells. Cardiovascular research, 1998, Volume: 40, Issue:1 Topics: 1-Methyl-3-isobutylxanthine; Atrial Natriuretic Factor; Cells, Cultured; Cyclic GMP; Dipyridamole; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Humans; Peptidyl-Dipeptidase A; Phosphodiesterase Inhibitors; Protein Kinase Inhibitors; Purinones; Stimulation, Chemical; Thionucleotides; Umbilical Veins; Vasodilator Agents	1998
Regulation of natriuretic peptide (urodilatin) release in a human kidney cell line. Kidney international, 1999, Volume: 55, Issue:1 Topics: 1-Methyl-3-isobutylxanthine; Atrial Natriuretic Factor; Calcimycin; Cell Line; Colforsin; Culture Media; Cyclic AMP; Cyclic GMP; Guanylate Cyclase; Humans; Intracellular Fluid; Kidney; Osmolar Concentration; Peptide Fragments; Radioimmunoassay; Tetradecanoylphorbol Acetate	1999
The metabotropic receptor mGluR6 may signal through G(o), but not phosphodiesterase, in retinal bipolar cells. The Journal of neuroscience : the official journal of the Society for Neuroscience, 1999, Apr-15, Volume: 19, Issue:8 Topics: 1-Methyl-3-isobutylxanthine; Animals; Cyclic GMP; Glutamic Acid; In Vitro Techniques; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Receptors, Metabotropic Glutamate; Resting Phase, Cell Cycle; Retina; Signal Transduction; Thionucleotides; Urodela	1999
Ascorbate and dehydroascorbate modulate nitric oxide-induced vasodilations of rat coronary arteries. Journal of cardiovascular pharmacology, 1999, Volume: 34, Issue:2 Topics: 1-Methyl-3-isobutylxanthine; Animals; Ascorbic Acid; Coronary Vessels; Cyclic GMP; Dehydroascorbic Acid; Male; Nitric Oxide; Rats; Rats, Sprague-Dawley; Vasodilation	1999
Elevated cAMP suppresses muscarinic inhibition of L-type calcium current in guinea pig ventricular myocytes. Journal of cardiovascular pharmacology, 1999, Volume: 34, Issue:2 Topics: 1-Methyl-3-isobutylxanthine; Animals; Calcium Channels; Calcium Channels, L-Type; Carbachol; Cyclic AMP; Cyclic GMP; Guinea Pigs; Muscarinic Agonists; Okadaic Acid; Phosphoprotein Phosphatases	1999
cGMP-mediated negative-feedback regulation of endothelial nitric oxide synthase expression by nitric oxide. Hypertension (Dallas, Tex. : 1979), 1999, Volume: 34, Issue:6 Topics: 1-Methyl-3-isobutylxanthine; Animals; Cells, Cultured; Coronary Vessels; Cyclic GMP; Down-Regulation; Endothelium, Vascular; Feedback; Guanylate Cyclase; Hemoglobins; Humans; Isosorbide Dinitrate; Male; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Oxadiazoles; Penicillamine; Phosphodiesterase Inhibitors; Quinoxalines; Rats; Rats, Sprague-Dawley; Up-Regulation; Vasodilator Agents	1999
Role of cyclic GMP in glutamate neurotoxicity in primary cultures of cerebellar neurons. Neuropharmacology, 1999, Volume: 38, Issue:12 Topics: 1-Methyl-3-isobutylxanthine; Animals; Cell Death; Cells, Cultured; Cerebellum; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Glutamic Acid; Guanylate Cyclase; Neurons; Neuroprotective Agents; Nitric Oxide; Penicillamine; Phosphodiesterase Inhibitors; Rats	1999
Nitric oxide modulates a late step of exocytosis. The Journal of biological chemistry, 2000, Jul-07, Volume: 275, Issue:27 Topics: 1-Methyl-3-isobutylxanthine; Animals; Barium; Catecholamines; Cattle; Chromaffin Cells; Chromaffin Granules; Cyclic GMP; Electrochemistry; Exocytosis; Kinetics; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroprusside; Nitroso Compounds	2000
The cGMP-dependent protein kinase stimulates the basolateral 18-pS K channel of the rat CCD. American journal of physiology. Cell physiology, 2000, Volume: 278, Issue:6 Topics: 1-Methyl-3-isobutylxanthine; Alkaloids; Animals; Carbazoles; Cell Membrane; Cyclic AMP; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Enzyme Inhibitors; Indoles; Kidney Cortex; Kidney Tubules, Collecting; Membrane Potentials; Patch-Clamp Techniques; Potassium Channels; Rats; Rats, Sprague-Dawley	2000
Effects of N(G)-monomethyl-L-arginine on Ca(2+) current and nitric-oxide synthase in rat ventricular myocytes. The Journal of pharmacology and experimental therapeutics, 2000, Volume: 294, Issue:1 Topics: 1-Methyl-3-isobutylxanthine; Acetylcholine; Animals; Calcium Channels, L-Type; Colforsin; Cyclic GMP; Enzyme Inhibitors; Milrinone; NADPH Dehydrogenase; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Rats	2000
Guanosine 3',5'-cyclic monophosphate mediated inhibition of cell death induced by nerve growth factor withdrawal and beta-amyloid: protective effects of propentofylline. Neuroscience, 2000, Volume: 99, Issue:4 Topics: 1-Methyl-3-isobutylxanthine; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Amyloid beta-Peptides; Animals; Apoptosis; Caspase 3; Caspases; Cyclic GMP; Dose-Response Relationship, Drug; Nerve Growth Factor; Neurons; Neuroprotective Agents; Nitric Oxide; Nitric Oxide Donors; PC12 Cells; Penicillamine; Peptide Fragments; Phosphodiesterase Inhibitors; Rats; Rolipram; Xanthines	2000
Activation of the human, intermediate-conductance, Ca2+-activated K+ channel by methylxanthines. Pflugers Archiv : European journal of physiology, 2000, Volume: 440, Issue:6 Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Caffeine; Calcium; Cell Line; Colforsin; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Electric Conductivity; Enzyme Inhibitors; Gene Expression; Humans; Magnesium; Membrane Potentials; Nitroprusside; Patch-Clamp Techniques; Potassium Channels; Recombinant Proteins; Theophylline; Transfection; Xanthines	2000
cGMP-dependent protein kinase mediates stimulation of L-type calcium current by cGMP in rabbit atrial cells. Cardiovascular research, 2000, Volume: 48, Issue:2 Topics: 1-Methyl-3-isobutylxanthine; Adrenergic beta-Agonists; Alkaloids; Animals; Blotting, Western; Calcium Channels, L-Type; Carbazoles; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Enzyme Inhibitors; Heart Atria; Indoles; Isoproterenol; Myocardium; Nitric Oxide Donors; Patch-Clamp Techniques; Phosphodiesterase Inhibitors; Rabbits; Stimulation, Chemical; Time Factors	2000
Odorant-induced hyperpolarization and suppression of cAMP-activated current in newt olfactory receptor neurons. Chemical senses, 2001, Volume: 26, Issue:1 Topics: 1-Methyl-3-isobutylxanthine; Animals; Anisoles; Cyclic AMP; Cyclic GMP; In Vitro Techniques; Membrane Potentials; Odorants; Olfactory Receptor Neurons; Patch-Clamp Techniques; Pentanols; Salamandridae	2001
Nitric oxide attenuates H(2)O(2)-induced endothelial barrier dysfunction: mechanisms of protection. American journal of physiology. Lung cellular and molecular physiology, 2001, Volume: 280, Issue:1 Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Endothelium, Vascular; Enzyme Inhibitors; Hydrogen Peroxide; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Oxadiazoles; Oxidants; Penicillamine; Phosphodiesterase Inhibitors; Pulmonary Artery; Quinoxalines; Swine; Thionucleotides	2001
Identification and characterization of DdPDE3, a cGMP-selective phosphodiesterase from Dictyostelium. The Biochemical journal, 2001, Feb-01, Volume: 353, Issue:Pt 3 Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-GMP Phosphodiesterases; Amino Acid Sequence; Animals; Base Sequence; Catalytic Domain; Cations, Divalent; Cloning, Molecular; Cyclic GMP; Dictyostelium; DNA, Recombinant; Escherichia coli; Gene Expression Regulation, Enzymologic; Molecular Sequence Data; RNA, Messenger; Sequence Homology, Amino Acid	2001
Amylin potently activates AP neurons possibly via formation of the excitatory second messenger cGMP. American journal of physiology. Regulatory, integrative and comparative physiology, 2001, Volume: 281, Issue:6 Topics: 1-Methyl-3-isobutylxanthine; Amyloid; Animals; Cerebral Ventricles; Cyclic GMP; Genes, fos; In Vitro Techniques; Islet Amyloid Polypeptide; Male; Neurons; omega-N-Methylarginine; Peptide Fragments; Peptides; Rats; Rats, Wistar; Second Messenger Systems	2001
Cyclic AMP-mediated increase in L-type calcium current (ICa,L) by nitroglycerin in guinea-pig ventricular myocytes. Cellular and molecular biology (Noisy-le-Grand, France), 2002, Volume: 48, Issue:2 Topics: 1-Methyl-3-isobutylxanthine; Animals; Calcium Signaling; Cells, Cultured; Cyclic AMP; Cyclic GMP; Dialysis; Guinea Pigs; Heart Ventricles; Isoproterenol; Methylene Blue; Nitroglycerin	2002
Relationship between bicarbonate and cyclic nucleotide in the promoting effects on head-to-head agglutination in boar spermatozoa. Asian journal of andrology, 2002, Volume: 4, Issue:2 Topics: 1-Methyl-3-isobutylxanthine; Animals; Bucladesine; Cyclic AMP; Cyclic GMP; Male; Papaverine; Purinergic P1 Receptor Antagonists; Sodium Bicarbonate; Sperm Agglutination; Sperm Head; Swine; Theophylline	2002
Potentiation of slow component of delayed rectifier K(+) current by cGMP via two distinct mechanisms: inhibition of phosphodiesterase 3 and activation of protein kinase G. British journal of pharmacology, 2002, Volume: 137, Issue:1 Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Atrial Natriuretic Factor; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Cyclic Nucleotide Phosphodiesterases, Type 3; Delayed Rectifier Potassium Channels; Enzyme Activation; Female; Guinea Pigs; In Vitro Techniques; Membrane Potentials; Patch-Clamp Techniques; Phosphodiesterase Inhibitors; Potassium Channels; Potassium Channels, Voltage-Gated; Sinoatrial Node	2002
Cardiac enkephalins attenuate vagal bradycardia: interactions with NOS-1-cGMP systems in canine sinoatrial node. American journal of physiology. Heart and circulatory physiology, 2003, Volume: 285, Issue:5 Topics: 1-Methyl-3-isobutylxanthine; Animals; Arginine; Bradycardia; Cyclic GMP; Dogs; Dose-Response Relationship, Drug; Enkephalin, Methionine; Enzyme Inhibitors; Indazoles; Methacholine Chloride; NG-Nitroarginine Methyl Ester; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Parasympathomimetics; Penicillamine; Phosphodiesterase Inhibitors; Sinoatrial Node; Vagus Nerve	2003
Provasopressin expression by breast cancer cells: implications for growth and novel treatment strategies. Breast cancer research and treatment, 2006, Volume: 95, Issue:3 Topics: 1-Methyl-3-isobutylxanthine; Anti-Inflammatory Agents; Antibodies, Monoclonal; Arginine Vasopressin; Blotting, Western; Breast Neoplasms; Cell Proliferation; Cyclic GMP; Dexamethasone; Female; Glycopeptides; Humans; Hypothalamus; Immunoenzyme Techniques; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Ovarian Neoplasms; Phosphodiesterase Inhibitors; Phosphorylation; Protein Precursors; Reverse Transcriptase Polymerase Chain Reaction	2006
Nitric oxide production from rat adipocytes is modulated by beta3-adrenergic receptor agonists and is involved in a cyclic AMP-dependent lipolysis in adipocytes. Nitric oxide : biology and chemistry, 2006, Volume: 14, Issue:3 Topics: 1-Methyl-3-isobutylxanthine; Adenine; Adenylyl Cyclase Inhibitors; Adipocytes; Adrenergic Agonists; Adrenergic beta-3 Receptor Agonists; Animals; Colforsin; Cyclic AMP; Cyclic GMP; Lipolysis; Male; Nitric Oxide; Nitric Oxide Donors; Rats; Rats, Wistar; S-Nitroso-N-Acetylpenicillamine	2006
Hyaluronan export by the ABC transporter MRP5 and its modulation by intracellular cGMP. The Journal of biological chemistry, 2007, Jul-20, Volume: 282, Issue:29 Topics: 1-Methyl-3-isobutylxanthine; Biological Transport; Cell Membrane; Cyclic GMP; Cytosol; Fibroblasts; Humans; Hyaluronic Acid; Models, Biological; Multidrug Resistance-Associated Proteins; NG-Nitroarginine Methyl Ester; Purinones; RNA Interference; Xanthines	2007
Involvement of the cGMP pathway in mediating the insulin-inhibitory effect of melatonin in pancreatic beta-cells. Journal of pineal research, 2008, Volume: 45, Issue:3 Topics: 1-Methyl-3-isobutylxanthine; Animals; Brain; Cell Line, Tumor; Colforsin; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 2; Cyclic Nucleotide-Gated Cation Channels; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Glucose; Guanylate Cyclase; Insulin; Insulin Secretion; Insulin-Secreting Cells; Insulinoma; Melatonin; Pineal Gland; Rats; Rats, Wistar; Receptor, Melatonin, MT2; Signal Transduction; Tetrahydronaphthalenes; Tryptamines	2008
Cyclic-AMP-dependent proliferation of a human osteoblast cell line (HOS cells) induced by hydroxyapatite: effect of exogenous nitric oxide. Acta bio-medica : Atenei Parmensis, 2008, Volume: 79, Issue:2 Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Adenylyl Cyclases; Arginase; Cell Communication; Cell Differentiation; Cell Line; Colforsin; Colorimetry; Cyclic AMP; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Dichlororibofuranosylbenzimidazole; Durapatite; Guanylate Cyclase; Humans; Nitric Oxide; Nitric Oxide Donors; Osteoblasts; Penicillamine; Phosphodiesterase Inhibitors; Rolipram; S-Nitroso-N-Acetylpenicillamine	2008
Complex interactions of NO/cGMP/PKG systems on Ca2+ signaling in afferent arteriolar vascular smooth muscle. American journal of physiology. Heart and circulatory physiology, 2010, Volume: 298, Issue:1 Topics: 1-Methyl-3-isobutylxanthine; ADP-ribosyl Cyclase; Animals; Arterioles; Calcium; Calcium Signaling; Carbazoles; Cyclic AMP; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Enzyme Activators; Enzyme Inhibitors; Male; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Donors; Nitroprusside; Oxadiazoles; Peptides; Phosphodiesterase Inhibitors; Potassium Chloride; Quinoxalines; Rats; Rats, Sprague-Dawley	2010
Role of soluble guanylyl cyclase-cyclic GMP signaling in tumor cell proliferation. Nitric oxide : biology and chemistry, 2010, Jan-01, Volume: 22, Issue:1 Topics: 1-Methyl-3-isobutylxanthine; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cyclic GMP; Enzyme Inhibitors; Guanylate Cyclase; Humans; Mitogen-Activated Protein Kinases; Neoplasms; Nitric Oxide; Nitroso Compounds; Phosphorylation; Pyrazoles; Pyridines; Receptors, Cytoplasmic and Nuclear; Signal Transduction; Soluble Guanylyl Cyclase; Structure-Activity Relationship	2010
Grueneberg ganglion neurons are finely tuned cold sensors. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2010, Jun-02, Volume: 30, Issue:22 Topics: 1-Methyl-3-isobutylxanthine; Animals; Animals, Newborn; Calcium; Calcium Signaling; Cold Temperature; Colforsin; Cyclic GMP; Cyclic Nucleotide-Gated Cation Channels; Ganglia, Sensory; Green Fluorescent Proteins; In Vitro Techniques; Isothiocyanates; Mice; Mice, Transgenic; Microscopy, Confocal; Nasal Cavity; Olfactory Bulb; Olfactory Marker Protein; Olfactory Pathways; Phosphodiesterase Inhibitors; Pyrimidinones; Sensory Receptor Cells; Sodium Channel Blockers; Tetrodotoxin; Thermosensing; Time Factors; Transient Receptor Potential Channels; TRPA1 Cation Channel	2010
Dual role of cyclic GMP in cardiac cell survival. The international journal of biochemistry & cell biology, 2013, Volume: 45, Issue:8 Topics: 1-Methyl-3-isobutylxanthine; Animals; Carbazoles; Cell Adhesion Molecules; Cell Line; Cell Survival; Cyclic GMP; Fluorescence; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Insulin; Marine Toxins; Microfilament Proteins; Myocytes, Cardiac; Oxazoles; Phosphoproteins; Phosphorylation; Phosphoserine; Proto-Oncogene Proteins c-akt; Rats	2013
Poly (I:C) impairs NO donor-induced relaxation by overexposure to NO via the NF-kappa B/iNOS pathway in rat superior mesenteric arteries. Free radical biology & medicine, 2017, Volume: 112 Topics: 1-Methyl-3-isobutylxanthine; Animals; Cyclic GMP; Endothelium, Vascular; Gene Expression Regulation; Interferon-Induced Helicase, IFIH1; Male; Mesenteric Artery, Superior; NF-kappa B; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase Type II; Nitroprusside; Poly I-C; Rats; Rats, Wistar; RNA Helicases; Signal Transduction; Tissue Culture Techniques; Toll-Like Receptor 3; Vasodilation	2017
cAMP signaling primes lung endothelial cells to activate caspase-1 during American journal of physiology. Lung cellular and molecular physiology, 2020, 05-01, Volume: 318, Issue:5 Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Adenine; Alprostadil; Animals; Caspase 1; Cell Proliferation; Colforsin; Cyclic AMP; Cyclic GMP; Dinoprostone; Endothelial Cells; Gene Expression Regulation; Host-Pathogen Interactions; Inflammasomes; Interleukin-1beta; Lung; Primary Cell Culture; Pseudomonas aeruginosa; Rats; Rolipram; Signal Transduction; Single-Cell Analysis	2020