1-methyl-3-isobutylxanthine and 4,5-dihydro-6-(4-(imidazol-1-yl)phenyl)-5-methyl-3(2h)-pyridazinone

1-methyl-3-isobutylxanthine has been researched along with 4,5-dihydro-6-(4-(imidazol-1-yl)phenyl)-5-methyl-3(2h)-pyridazinone in 4 studies

Research

Studies (4)

Timeframe	Studies, this research(%)	All Research%
pre-1990	1 (25.00)	18.7374
1990's	3 (75.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Bristol, JA; Cain, MH; Weishaar, RE	1
Moreno, S; Tomes, C	1
Abdel-Aleem, S; Badr, M; Frangakis, C	1
Arauz, E; Fitzpatrick, DF; Krzanowski, JJ; Pan, X; Polson, JB	1

Reviews

1 review(s) available for 1-methyl-3-isobutylxanthine and 4,5-dihydro-6-(4-(imidazol-1-yl)phenyl)-5-methyl-3(2h)-pyridazinone

Article	Year
A new generation of phosphodiesterase inhibitors: multiple molecular forms of phosphodiesterase and the potential for drug selectivity. Journal of medicinal chemistry, 1985, Volume: 28, Issue:5 Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Blood Platelets; Calmodulin; Cardiotonic Agents; Guinea Pigs; Humans; Hypersensitivity; In Vitro Techniques; Lung Diseases; Myocardium; Platelet Aggregation; Substrate Specificity	1985

Article

Year

A new generation of phosphodiesterase inhibitors: multiple molecular forms of phosphodiesterase and the potential for drug selectivity.

Journal of medicinal chemistry, 1985, Volume: 28, Issue:5

Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Blood Platelets; Calmodulin; Cardiotonic Agents; Guinea Pigs; Humans; Hypersensitivity; In Vitro Techniques; Lung Diseases; Myocardium; Platelet Aggregation; Substrate Specificity

1985

Other Studies

3 other study(ies) available for 1-methyl-3-isobutylxanthine and 4,5-dihydro-6-(4-(imidazol-1-yl)phenyl)-5-methyl-3(2h)-pyridazinone

Article	Year
cAMP analogs and selective inhibitors used to study low Km Mucor rouxii cAMP phosphodiesterase. The International journal of biochemistry, 1990, Volume: 22, Issue:9 Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Centrifugation, Density Gradient; Cyclic AMP; Cyclic GMP; Dipyridamole; Hydrolysis; Mucor; Nicotinic Acids; Papaverine; Pyridazines; Theophylline	1990
Stimulation of fatty acid oxidation in myocytes by phosphodiesterase inhibitors and adenosine analogues. Life sciences, 1991, Volume: 48, Issue:18 Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Amrinone; Animals; Cells, Cultured; Dipyridamole; Enoximone; Heart; Imidazoles; Milrinone; Myocardium; Oxidation-Reduction; Palmitic Acid; Palmitic Acids; Phosphodiesterase Inhibitors; Purinones; Pyridazines; Pyridones; Rats	1991
Synergistic interactions between selective pharmacological inhibitors of phosphodiesterase isozyme families PDE III and PDE IV to attenuate proliferation of rat vascular smooth muscle cells. Biochemical pharmacology, 1994, Aug-17, Volume: 48, Issue:4 Topics: 1-Methyl-3-isobutylxanthine; Animals; Cell Division; Cell Line; Drug Synergism; Isoenzymes; Models, Chemical; Muscle, Smooth, Vascular; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Pyridazines; Pyrrolidinones; Quinolones; Rats; Rolipram; Thymidine	1994