1-methyl-3-isobutylxanthine and 2-keto-4-methylvalerate

1-methyl-3-isobutylxanthine has been researched along with 2-keto-4-methylvalerate in 18 studies

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19908 (44.44)18.7374
1990's5 (27.78)18.2507
2000's4 (22.22)29.6817
2010's1 (5.56)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Halestrap, AP; Manning Fox, JE; Meredith, D1
Bergamini, E; Bombara, M; Fierabracci, V; Masiello, P; Novelli, M1
Cerasi, E; Corcos, AP; Kaiser, N; Sarel, I1
Arroyo, JA; Cervera, T; Ortiz, MA; Perez, A; Pou, JM1
Grodsky, GM; Schmid-Formby, F1
Grill, V; Rundfeldt, M1
Kelly, KJ; Rayfield, EJ1
Hoenig, M; MacGregor, LC; Matschinsky, FM1
Bolaffi, JL; Bruno, L; Grodsky, GM; Heldt, A1
Grill, V1
Cvet, D; Logothetopoulos, J; Valiquette, N1
Efendić, S; Grill, V1
Bergamini, E; Bombara, M; Masiello, P; Novelli, M1
Abdel-Halim, SM; Efendic, S; Guenifi, A; Ostenson, CG1
Bergamini, E; Bombara, M; De Tata, V; Masiello, P; Novelli, M1
Bergamini, E; Bombara, M; Fierabracci, V; Masiello, P; Novelli, M; Prentki, M; Vittorini, S1
Flatt, PR; McClenaghan, NH; Picton, SF1
Gurgul-Convey, E; Kaminski, MT; Lenzen, S1

Other Studies

18 other study(ies) available for 1-methyl-3-isobutylxanthine and 2-keto-4-methylvalerate

ArticleYear
Characterisation of human monocarboxylate transporter 4 substantiates its role in lactic acid efflux from skeletal muscle.
    The Journal of physiology, 2000, Dec-01, Volume: 529 Pt 2

    Topics: Animals; Biological Transport, Active; Carrier Proteins; Cells, Cultured; Fluoresceins; Fluorescent Dyes; Humans; Kinetics; Lactic Acid; Monocarboxylic Acid Transporters; Muscle Proteins; Muscle, Skeletal; Oocytes; Protein Isoforms; Substrate Specificity; Xenopus

2000
Effects of different regimens of dietary restriction on the age-related decline in insulin secretory response of isolated rat pancreatic islets.
    Annals of the New York Academy of Sciences, 1991, Volume: 621

    Topics: 1-Methyl-3-isobutylxanthine; Aging; Animals; Arginine; Diet, Reducing; Energy Intake; Glucose; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Keto Acids; Male; Potassium Chloride; Rats; Rats, Inbred Strains; Reference Values

1991
Monolayer culture of adult rat pancreatic islets on extracellular matrix: modulation of B-cell function by chronic exposure to high glucose.
    Endocrinology, 1991, Volume: 129, Issue:4

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Cells, Cultured; Cytological Techniques; Extracellular Matrix; Glucose; Glyceraldehyde; Insulin; Islets of Langerhans; Keto Acids; Osmolar Concentration; Rats; Time Factors

1991
Effect of L-asparaginase on insulin secretion from isolated rat islets of Langerhans.
    Hormone research, 1991, Volume: 35, Issue:3-4

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Asparaginase; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Glucose; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Keto Acids; Kinetics; Male; Rats; Rats, Inbred Strains; Tolbutamide

1991
Kinetic and quantitative relationships between insulin release and 65Zn efflux from perifused islets.
    Endocrinology, 1985, Volume: 117, Issue:2

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Cells, Cultured; Colforsin; Diterpenes; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Keto Acids; Kinetics; Leucine; Male; Rats; Zinc; Zinc Radioisotopes

1985
Abnormalities of insulin responses after ambient and previous exposure to glucose in streptozocin-diabetic and dexamethasone-treated rats. Role of hyperglycemia and increased B-cell demands.
    Diabetes, 1986, Volume: 35, Issue:1

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Blood Glucose; Dexamethasone; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Female; Glucose; Glyceraldehyde; Humans; Hyperglycemia; Insulin; Insulin Secretion; Islets of Langerhans; Keto Acids; Male; Rats; Rats, Inbred Strains

1986
Virus-induced alterations in cyclic adenosine monophosphate generation in hamster islets of Langerhans.
    The Journal of clinical investigation, 1986, Volume: 77, Issue:3

    Topics: 1-Methyl-3-isobutylxanthine; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Animals; Cricetinae; Cyclic AMP; Glucagon; Glucose; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Keto Acids; Secretory Rate

1986
In vitro exhaustion of pancreatic beta-cells.
    The American journal of physiology, 1986, Volume: 250, Issue:5 Pt 1

    Topics: 1-Methyl-3-isobutylxanthine; Amino Acids; Animals; Arachidonic Acid; Arachidonic Acids; Buffers; Culture Media; Glucose; In Vitro Techniques; Inositol; Insulin; Insulin Secretion; Islets of Langerhans; Keto Acids; Male; Perfusion; Rats; Rats, Inbred Strains; Time Factors

1986
Characteristics of desensitization of insulin secretion in fully in vitro systems.
    Endocrinology, 1988, Volume: 122, Issue:5

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Colforsin; Glucose; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Keto Acids; Kinetics; Male; Rats; Tetradecanoylphorbol Acetate; Time Factors

1988
Nutrient-induced priming of insulin and glucagon secretion. Effects of alpha-ketoisocaproic acid.
    Endocrinology, 1982, Volume: 110, Issue:3

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Arginine; Caproates; Glucagon; Insulin; Insulin Secretion; Islets of Langerhans; Keto Acids; Kinetics; Male; Rats; Rats, Inbred Strains

1982
Glucose stimulation of beta-cell DNA replication in the intact rat and in pancreatic islets in suspension culture. Effects of alpha-ketoisocaproic acid, dibutyryl cyclic AMP, and 3-isobutyl-1-methylxanthine in the in vitro system.
    Diabetes, 1983, Volume: 32, Issue:12

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Bucladesine; Cells, Cultured; DNA Replication; Glucose; Islets of Langerhans; Keto Acids; Male; Rats; Rats, Inbred Strains; Theophylline; Thymidine

1983
Abnormal D cell secretion in alloxan-diabetes: influence by drug and aberrant metabolism.
    The American journal of physiology, 1984, Volume: 246, Issue:6 Pt 1

    Topics: 1-Methyl-3-isobutylxanthine; Alloxan; Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Glucose; Glyceraldehyde; In Vitro Techniques; Islets of Langerhans; Keto Acids; Male; Pancreas; Pancreatic Hormones; Rats; Rats, Inbred Strains; Somatostatin; Time Factors

1984
Impairment of the priming effect of glucose on insulin secretion from isolated islets of aging rats.
    Acta diabetologica, 1995, Volume: 32, Issue:1

    Topics: 1-Methyl-3-isobutylxanthine; Aging; Animals; Arginine; Blood Glucose; Glucose; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Keto Acids; Kinetics; Male; Rats; Rats, Sprague-Dawley

1995
Preserved initiatory and potentiatory effect of alpha-ketoisocaproate on insulin release in islets of glucose intolerant rats.
    Diabetologia, 1998, Volume: 41, Issue:11

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Cells, Cultured; Crosses, Genetic; Diabetes Mellitus, Type 2; Female; Glucose; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Keto Acids; Kinetics; Male; Perfusion; Rats; Rats, Inbred Strains; Rats, Wistar

1998
Age-dependent reduction in GLUT-2 levels is correlated with the impairment of the insulin secretory response in isolated islets of Sprague-Dawley rats.
    Experimental gerontology, 2000, Volume: 35, Issue:5

    Topics: 1-Methyl-3-isobutylxanthine; Aging; Animals; Glucose Transporter Type 2; Insulin; Insulin Secretion; Islets of Langerhans; Keto Acids; Male; Monosaccharide Transport Proteins; Rats; Rats, Sprague-Dawley

2000
The antilipolytic agent 3,5-dimethylpyrazole inhibits insulin release in response to both nutrient secretagogues and cyclic adenosine monophosphate agonists in isolated rat islets.
    Metabolism: clinical and experimental, 2002, Volume: 51, Issue:1

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Cyclic AMP; Diglycerides; Glucagon; Glucose; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Keto Acids; Lipolysis; Male; Nutritional Physiological Phenomena; Pyrazoles; Rats; Rats, Sprague-Dawley

2002
Differential acute and long term actions of succinic acid monomethyl ester exposure on insulin-secreting BRIN-BD11 cells.
    International journal of experimental diabetes research, 2001, Volume: 2, Issue:1

    Topics: 1-Methyl-3-isobutylxanthine; Amino Acids; Animals; Caproates; Cell Line; Cell Survival; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Keto Acids; Kinetics; Succinates

2001
Physiological characterization of the human EndoC-βH1 β-cell line.
    Biochemical and biophysical research communications, 2015, Aug-14, Volume: 464, Issue:1

    Topics: 1-Methyl-3-isobutylxanthine; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adenosine Diphosphate; Adenosine Triphosphate; Biological Transport; Calcium Channels; Cell Line; Colforsin; Founder Effect; Gene Expression; Glucokinase; Glucose; Glucose Transporter Type 1; Glucose Transporter Type 2; Glutamine; Glyburide; Humans; Insulin; Insulin-Secreting Cells; Keto Acids; Leucine; Mannoheptulose; Phosphorylation; Potassium Channels, Inwardly Rectifying

2015