1-methyl-3-isobutylxanthine has been researched along with 2-chloroadenosine in 38 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 27 (71.05) | 18.7374 |
| 1990's | 9 (23.68) | 18.2507 |
| 2000's | 2 (5.26) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET | 1 |
| Daly, JW | 1 |
| Bertin, B; Freissmuth, M; Hohenegger, M; Jockers, R; Linder, ME; Marullo, S; Nanoff, C; Strosberg, AD | 1 |
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Richter, J | 1 |
| Ishimura, Y; Kizaki, H; Suzuki, K; Tadakuma, T | 1 |
| Mohell, N; Nedergaard, J; Unelius, L | 1 |
| Farb, DH; Friedman, L; Gibbs, TT; Roca, DJ; Rozenberg, I; Schiller, GD | 1 |
| Nathan, C; Sanchez, E | 1 |
| Churchill, PC; Wu, PH | 1 |
| Kitos, TE; Michaelis, ML; Mooney, T | 1 |
| Gerber, JG; Nies, AS; Payne, NA | 1 |
| Dzierzanowski, D; McCarthy, L; Schimmel, RJ | 1 |
| Hoskins, DD; Vijayaraghavan, S | 1 |
| Birch, RE; Polmar, SH | 1 |
| Dolphin, AC; Forda, SR; Scott, RH | 1 |
| Kelly, E; Nahorski, SR | 1 |
| Fox, IH; John, D | 1 |
| Brown, SJ; Richardson, PJ | 1 |
| Paes de Carvalho, R; Ventura, AL | 1 |
| Brady, MJ; Nairn, AC; Nichols, RA; Palfrey, HC | 1 |
| Beek, D; Kenakin, TP | 1 |
| Berry-Kravis, E; Dawson, G; Derechin, V; Kazmierczak, BI | 1 |
| Ribeiro, JA; Sebastião, AM | 1 |
| Adams, RN; Johe, KK; Michaelis, ML; Moghadam, B | 1 |
| Alexander, SP; Hill, SJ; Kendall, DA | 1 |
| de Mello, FG; Paes de Carvalho, R | 2 |
| d'Almeida, MS; Lautt, WW; Legare, DJ | 1 |
| Dobson, JG; Frohloff, N; LaMonica, DA | 1 |
| Galloway, MP; Roth, RH | 1 |
| Budohoski, L; Challiss, RA; McManus, B; Newsholme, EA | 1 |
| McCarthy, L; Schimmel, RJ | 1 |
| Dobbins, JW; Forrest, JN; Laurenson, JP | 1 |
| Challiss, RA; Morgan, AJ; Murray, KJ | 1 |
| Monteiro, EC; Monteiro, TC; Silva e Sousa, MA; Vera-Cruz, P | 1 |
| Halgren, RG; Heller, KF; Krett, NL; Pillay, S; Rosen, ST; Traynor, AE; Zell, JL | 1 |
| Bauer, A; Greene, E; Hsiao, HP; Krett, NL; Leitner, WW; Nesterova, M; Robinson-White, AJ; Stratakis, CA | 1 |
1 review(s) available for 1-methyl-3-isobutylxanthine and 2-chloroadenosine
| Article | Year |
|---|---|
Adenosine receptors: targets for future drugs.
Topics: Adenosine; Adenosine Triphosphate; Animals; Humans; Ligands; Receptors, Cell Surface; Receptors, Purinergic; Structure-Activity Relationship; Xanthines | 1982 |
37 other study(ies) available for 1-methyl-3-isobutylxanthine and 2-chloroadenosine
| Article | Year |
|---|---|
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium | 1985 |
Species difference in the G protein selectivity of the human and bovine A1-adenosine receptor.
Topics: Animals; Base Sequence; Brain; Cattle; DNA Primers; Escherichia coli; GTP-Binding Proteins; Humans; Molecular Sequence Data; Protein Binding; Receptors, Purinergic P1; Recombinant Proteins; Species Specificity | 1994 |
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Effect of adenosine analogues and cAMP-raising agents on TNF-, GM-CSF-, and chemotactic peptide-induced degranulation in single adherent neutrophils.
Topics: 1-Methyl-3-isobutylxanthine; 2-Chloroadenosine; Adenosine; Blood Proteins; Bucladesine; Cell Adhesion; Cell Degranulation; Chemotactic Factors; Colforsin; Cyclic AMP; Cytochalasin B; Exocytosis; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1992 |
Adenosine receptor-mediated accumulation of cyclic AMP-induced T-lymphocyte death through internucleosomal DNA cleavage.
Topics: 1-Methyl-3-isobutylxanthine; 2-Chloroadenosine; 8-Bromo Cyclic Adenosine Monophosphate; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Bucladesine; Cell Survival; Cells, Cultured; Cholera Toxin; Colforsin; Cyclic AMP; Kinetics; Male; Mice; Mice, Inbred BALB C; Phenylisopropyladenosine; Receptors, Purinergic; T-Lymphocytes | 1990 |
Cold acclimation induces desensitization to adenosine in brown fat cells without changing receptor binding.
Topics: 1-Methyl-3-isobutylxanthine; 2-Chloroadenosine; Acclimatization; Adenosine; Adenosine Deaminase; Adipose Tissue, Brown; Animals; Cell Membrane; Cells, Cultured; Cold Temperature; Cricetinae; Edetic Acid; Kinetics; Magnesium; Male; Mesocricetus; Norepinephrine; Oxygen Consumption; Phenylisopropyladenosine; Receptors, Purinergic | 1990 |
gamma-Aminobutyric acidA receptor regulation in culture: altered allosteric interactions following prolonged exposure to benzodiazepines, barbiturates, and methylxanthines.
Topics: 1-Methyl-3-isobutylxanthine; 2-Chloroadenosine; Allosteric Regulation; Animals; Barbital; Barbiturates; Brain; Caffeine; Cells, Cultured; Chick Embryo; Flumazenil; Flunitrazepam; Flurazepam; gamma-Aminobutyric Acid; Kinetics; Neurons; Pentobarbital; Receptors, GABA-A; Tetrodotoxin; Theophylline; Veratridine | 1990 |
Tumor necrosis factor and CD11/CD18 (beta 2) integrins act synergistically to lower cAMP in human neutrophils.
Topics: 1-Methyl-3-isobutylxanthine; 2-Chloroadenosine; Actin Cytoskeleton; Actins; Antigens, Differentiation; Blood Proteins; Bucladesine; CD11 Antigens; CD18 Antigens; Cell Adhesion; Cell Movement; Colforsin; Cyclic AMP; Humans; Hydrogen Peroxide; Integrins; Kinetics; Neutrophils; Oxygen; Plastics; Receptors, Leukocyte-Adhesion; Tumor Necrosis Factor-alpha | 1990 |
2-Chloro-[3H]-adenosine binding in isolated rat kidney membranes.
Topics: 1-Methyl-3-isobutylxanthine; 2-Chloroadenosine; Adenosine; Animals; Binding, Competitive; In Vitro Techniques; Kidney; Rats; Receptors, Cell Surface; Receptors, Purinergic; Theophylline | 1985 |
Characteristics of adenosine binding sites in atrial sarcolemmal membranes.
Topics: 1-Methyl-3-isobutylxanthine; 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Binding Sites; Binding, Competitive; Cattle; Endopeptidases; Heart Atria; Myocardium; Sarcolemma; Subcellular Fractions; Theophylline; Time Factors | 1985 |
Adenosine receptors on canine parietal cells modulate gastric acid secretion to histamine.
Topics: 1-Methyl-3-isobutylxanthine; 2-Chloroadenosine; Adenosine; Animals; Dogs; Dose-Response Relationship, Drug; Female; Gastric Acid; Histamine; In Vitro Techniques; Male; Parietal Cells, Gastric; Phenylisopropyladenosine; Prostaglandins; Receptors, Cell Surface; Receptors, Purinergic; Theophylline | 1985 |
Effects of pertussis toxin treatment on metabolism in hamster brown adipocytes.
Topics: 1-Methyl-3-isobutylxanthine; 2-Chloroadenosine; Adenosine; Adenosine Deaminase; Adenylate Cyclase Toxin; Adenylyl Cyclases; Adipose Tissue, Brown; Animals; Cricetinae; Drug Synergism; Isoproterenol; Lipolysis; Male; Mesocricetus; NAD; Oxygen Consumption; Pertussis Toxin; Phenylephrine; Virulence Factors, Bordetella | 1985 |
Regulation of bovine sperm motility and cyclic adenosine 3',5'-monophosphate by adenosine and its analogues.
Topics: 1-Methyl-3-isobutylxanthine; 2-Chloroadenosine; Adenosine; Animals; Bicarbonates; Cattle; Cyclic AMP; Dibucaine; Male; Sperm Motility; Spermatozoa; Structure-Activity Relationship; Theophylline | 1986 |
Adenosine induced immunosuppression: the role of the adenosine receptor--adenylate cyclase interaction in the alteration of T-lymphocyte surface phenotype and immunoregulatory function.
Topics: 1-Methyl-3-isobutylxanthine; 2-Chloroadenosine; Adenosine; Adenylyl Cyclases; Adult; Antibodies, Monoclonal; Antigens, Surface; B-Lymphocytes; Cell Differentiation; Humans; Immune Tolerance; Isoproterenol; Kinetics; Receptors, Cell Surface; Receptors, Purinergic; T-Lymphocytes; Theophylline | 1986 |
Calcium-dependent currents in cultured rat dorsal root ganglion neurones are inhibited by an adenosine analogue.
Topics: 1-Methyl-3-isobutylxanthine; 2-Chloroadenosine; Action Potentials; Adenosine; Adenylyl Cyclases; Animals; Baclofen; Calcium; Cells, Cultured; Depression, Chemical; Ganglia, Spinal; Ion Channels; Neurons; Potassium; Rats; Tetraethylammonium; Tetraethylammonium Compounds; Theophylline | 1986 |
Specific inhibition of dopamine D-1-mediated cyclic AMP formation by dopamine D-2, muscarinic cholinergic, and opiate receptor stimulation in rat striatal slices.
Topics: 1-Methyl-3-isobutylxanthine; 2-Chloroadenosine; 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Adenosine; Alprostadil; Animals; Benzazepines; Carbachol; Cholera Toxin; Corpus Striatum; Cyclic AMP; Isoproterenol; Morphine; Phenethylamines; Rats; Receptors, Cholinergic; Receptors, Dopamine; Receptors, Muscarinic; Receptors, Opioid; Vasoactive Intestinal Peptide | 1986 |
Characteristics of high affinity and low affinity adenosine binding sites in human cerebral cortex.
Topics: 1-Methyl-3-isobutylxanthine; 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Cell Membrane; Cerebral Cortex; Humans; Kinetics; Phenylisopropyladenosine; Receptors, Purinergic; Theophylline | 1986 |
ATP release from affinity-purified rat cholinergic nerve terminals.
Topics: 1-Methyl-3-isobutylxanthine; 2-Chloroadenosine; Acetylcholine; Adenosine; Adenosine Triphosphate; Animals; Cholinergic Fibers; Chromatography, High Pressure Liquid; Potassium Chloride; Rats; Sheep; Theophylline; Veratridine | 1987 |
Development of adenosine-dependent cyclic AMP accumulation in the avian optic tectum.
Topics: 1-Methyl-3-isobutylxanthine; 2-Chloroadenosine; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenosine; Adenosine Deaminase; Animals; Chick Embryo; Cyclic AMP; Dipyridamole; Proteins; Superior Colliculi | 1987 |
Nerve growth factor treatment or cAMP elevation reduces Ca2+/calmodulin-dependent protein kinase III activity in PC12 cells.
Topics: 1-Methyl-3-isobutylxanthine; 2-Chloroadenosine; Adenosine; Adrenal Gland Neoplasms; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Colforsin; Cyclic AMP; Cytosol; Elongation Factor 2 Kinase; Epidermal Growth Factor; Kinetics; Nerve Growth Factors; Pheochromocytoma; Phosphorylation; Protein Kinases | 1987 |
Measurement of antagonist affinity for purine receptors of drugs producing concomitant phosphodiesterase blockade: the use of pharmacologic resultant analysis.
Topics: 1-Methyl-3-isobutylxanthine; 2-Chloroadenosine; Adenosine; Animals; Dose-Response Relationship, Drug; Guinea Pigs; Heart; In Vitro Techniques; Male; Phosphodiesterase Inhibitors; Purines; Rats; Rats, Inbred Strains; Receptors, Purinergic; Regression Analysis; Theophylline; Vas Deferens | 1987 |
Neuromodulator-mediated phosphorylation of specific proteins in a neurotumor hybrid cell line (NCB-20).
Topics: 1-Methyl-3-isobutylxanthine; 2-Chloroadenosine; Adenosine; Alprostadil; Animals; Brain; Calcimycin; Colforsin; Cricetinae; Cyclic AMP; Electrophoresis, Polyacrylamide Gel; Embryo, Mammalian; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Hybrid Cells; Immunoassay; Mice; Nerve Tissue Proteins; Neuroblastoma; Neurotransmitter Agents; Phosphoproteins; Phosphorylation; Protein Kinases; Serotonin; Tumor Cells, Cultured; Tyrosine 3-Monooxygenase | 1988 |
On the adenosine receptor and adenosine inactivation at the rat diaphragm neuromuscular junction.
Topics: 1-Methyl-3-isobutylxanthine; 2-Chloroadenosine; Adenosine; Animals; Diaphragm; Evoked Potentials; Female; In Vitro Techniques; Male; Motor Endplate; Muscle Contraction; Neuromuscular Junction; Rats; Rats, Inbred Strains; Receptors, Purinergic; Temperature; Theophylline | 1988 |
Studies on the ionic mechanism for the neuromodulatory actions of adenosine in the brain.
Topics: 1-Methyl-3-isobutylxanthine; 2-Chloroadenosine; Adenosine; Animals; Calcium; Male; Neurotransmitter Agents; Potassium; Potassium Channels; Rats; Rats, Inbred Strains; Synaptic Membranes; Synaptosomes; Thiocyanates; Valinomycin; Veratridine | 1988 |
Differences in the adenosine receptors modulating inositol phosphates and cyclic AMP accumulation in mammalian cerebral cortex.
Topics: 1-Methyl-3-isobutylxanthine; 2-Chloroadenosine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Cerebral Cortex; Colforsin; Cyclic AMP; Female; Guinea Pigs; In Vitro Techniques; Inositol Phosphates; Kinetics; Lithium; Male; Mice; Receptors, Purinergic; Second Messenger Systems; Xanthines | 1989 |
Expression of A1 adenosine receptors modulating dopamine-dependent cyclic AMP accumulation in the chick embryo retina.
Topics: 1-Methyl-3-isobutylxanthine; 2-Chloroadenosine; Adenosine; Animals; Apomorphine; Chick Embryo; Cyclic AMP; Dopamine; Dose-Response Relationship, Drug; Receptors, Cell Surface; Receptors, Purinergic; Retina | 1985 |
Adenosine as putative regulator of hepatic arterial flow (the buffer response).
Topics: 1-Methyl-3-isobutylxanthine; 2-Chloroadenosine; Adenosine; Animals; Blood Pressure; Cats; Dipyridamole; Hepatic Artery; Liver Circulation; Portal System; Rheology; Time Factors; Vasodilation | 1985 |
Adenosine inhibition of catecholamine-stimulated cardiac membrane adenylate cyclase.
Topics: 1-Methyl-3-isobutylxanthine; 2-Chloroadenosine; Adenosine; Adenosine Deaminase; Adenylyl Cyclase Inhibitors; Animals; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Guinea Pigs; Isoproterenol; Male; Myocardium; Phenylisopropyladenosine; Rats; Rats, Inbred Strains; Sodium Fluoride | 1985 |
Adenosine-elicited accumulation of adenosine 3', 5'-cyclic monophosphate in the chick embryo retina.
Topics: 1-Methyl-3-isobutylxanthine; 2-Chloroadenosine; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenosine; Animals; Cells, Cultured; Chick Embryo; Cyclic AMP; Dopamine Antagonists; Retina | 1982 |
Neuropharmacology of 3-isobutylmethylxanthine: effects on central noradrenergic systems in vivo.
Topics: 1-Methyl-3-isobutylxanthine; 2-Chloroadenosine; Adenosine; Animals; Axons; Brain; Clonidine; Diazepam; Dihydroxyphenylalanine; Hydroxylation; Male; Methoxyhydroxyphenylglycol; Neurons; Norepinephrine; Rats; Rats, Inbred Strains; Stimulation, Chemical; Theophylline; Tyrosine 3-Monooxygenase; Yohimbine | 1983 |
Effects of analogues of adenosine and methyl xanthines on insulin sensitivity in soleus muscle of the rat.
Topics: 1-Methyl-3-isobutylxanthine; 2-Chloroadenosine; Adenosine; Animals; Glucose; Glycogen; Glycolysis; Insulin; Lactates; Lactic Acid; Muscles; Phenylisopropyladenosine; Rats; Theophylline | 1984 |
Role of adenosine as an endogenous regulator of respiration in hamster brown adipocytes.
Topics: 1-Methyl-3-isobutylxanthine; 2-Chloroadenosine; Adenosine; Adenosine Deaminase; Adipose Tissue, Brown; Animals; Cricetinae; Deoxyadenosines; Dideoxyadenosine; Isoproterenol; Lipolysis; Male; Mesocricetus; Oxygen Consumption | 1984 |
Adenosine and adenosine analogues stimulate adenosine cyclic 3', 5'-monophosphate-dependent chloride secretion in the mammalian ileum.
Topics: 1-Methyl-3-isobutylxanthine; 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Biological Transport; Chlorides; Cyclic AMP; Cyclic GMP; Ileum; Kinetics; Male; Phenylisopropyladenosine; Rabbits; Theophylline | 1984 |
Comparison of the effect of isobutylmethylxanthine and phosphodiesterase-selective inhibitors on cAMP levels in SH-SY5Y neuroblastoma cells.
Topics: 1-Methyl-3-isobutylxanthine; 2-Chloroadenosine; Adenosine; Adenylyl Cyclase Inhibitors; Cell Line; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Humans; Neuroblastoma; Phosphodiesterase Inhibitors; Pyrrolidinones; Rolipram; Tumor Cells, Cultured | 1993 |
Adenosine increases the cAMP content of the rat carotid body in vitro.
Topics: 1-Methyl-3-isobutylxanthine; 2-Chloroadenosine; Adenine; Adenosine; Animals; Carotid Body; Cyclic AMP; Male; Nerve Tissue Proteins; Perfusion; Phenethylamines; Rats; Rats, Wistar; Receptors, Purinergic P1; Second Messenger Systems | 1996 |
8Cl-cAMP cytotoxicity in both steroid sensitive and insensitive multiple myeloma cell lines is mediated by 8Cl-adenosine.
Topics: 1-Methyl-3-isobutylxanthine; 2-Chloroadenosine; 8-Bromo Cyclic Adenosine Monophosphate; Adenosine Deaminase; Animals; Antimetabolites, Antineoplastic; Apoptosis; Biological Transport; Biotransformation; Cattle; Culture Media; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Humans; Interleukin-6; Multiple Myeloma; Phosphoric Diester Hydrolases; Prodrugs; Thioinosine; Tumor Cells, Cultured | 1998 |
Protein kinase A-independent inhibition of proliferation and induction of apoptosis in human thyroid cancer cells by 8-Cl-adenosine.
Topics: 1-Methyl-3-isobutylxanthine; 2-Chloroadenosine; 8-Bromo Cyclic Adenosine Monophosphate; Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cyclic AMP-Dependent Protein Kinases; Humans; Signal Transduction; Thyroid Neoplasms | 2008 |