1-methyl-3-isobutylxanthine and 2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one

1-methyl-3-isobutylxanthine has been researched along with 2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one in 15 studies

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (13.33)18.2507
2000's9 (60.00)29.6817
2010's3 (20.00)24.3611
2020's1 (6.67)2.80

Authors

AuthorsStudies
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Hirasawa, Y; Ifadotunnikmah, F; Kaneda, T; Koshikawa, S; Morita, H; Nugroho, AE; Tadahiro, S1
Carnero, A; Lacal, JC1
Ikeda, K; Kawada, N; Kuroki, T; Seki, S1
Grewal, SS; McCleskey, EW; Molliver, DC; Stenberg, PE; Stork, PJ; York, RD1
Byrnes, HD; Fine, JS; Hipkin, RW; Zavodny, PJ1
Shimada, M; Terada, T1
Bazan, NG; Bernatchez, PN; Gélinas, DS; Rollin, S; Sirois, MG1
Facci, L; Franceschini, D; Pangallo, M; Skaper, SD; Stevens, DA; Strijbos, PJ1
Andersson, TP; Sköld, HN; Svensson, SP1
Campbell, JR; Husted, RF; Thomas, CP; Wright, PJ1
Christensen, GP; Forte, JG; Ghayouri, S; Mettler, SE1
Jin, ML; Kim, YH; Lee, SJ; Park, G; Park, SY; Son, HJ1
Das, D; Khan, PP; Maitra, S1
Hyun, SK; Jin, KS; Kim, BW; Kwon, HJ; Oh, YN1

Other Studies

15 other study(ies) available for 1-methyl-3-isobutylxanthine and 2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one

ArticleYear
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Calofolic Acid-A from
    Journal of natural products, 2022, 09-23, Volume: 85, Issue:9

    Topics: Animals; Calcium; Calophyllum; Cyclic AMP-Dependent Protein Kinases; Isoproterenol; Muscle, Smooth, Vascular; Phenylephrine; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Plant Bark; Rats; Vasodilation; Vasodilator Agents

2022
Wortmannin, an inhibitor of phosphatidyl-inositol 3-kinase, induces oocyte maturation through a MPF-MAPK-dependent pathway.
    FEBS letters, 1998, Jan-30, Volume: 422, Issue:2

    Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Adenine; Androstadienes; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Chromones; Cycloheximide; Enzyme Activation; Enzyme Inhibitors; Female; In Vitro Techniques; Kinetics; Maturation-Promoting Factor; Morpholines; Oocytes; Phosphoinositide-3 Kinase Inhibitors; Signal Transduction; Wortmannin; Xenopus laevis

1998
Expression of cyclins D1, D2 and E correlates with proliferation of rat stellate cells in culture.
    Journal of hepatology, 1999, Volume: 30, Issue:6

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Blotting, Northern; Blotting, Western; Bromodeoxyuridine; Bucladesine; Cell Cycle; Cell Division; Cells, Cultured; Chromones; Cyclin D1; Cyclin D2; Cyclin E; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinases; Cyclins; DNA; Enzyme Inhibitors; Flavonoids; G1 Phase; Imidazoles; Liver; Male; Morpholines; Phosphoinositide-3 Kinase Inhibitors; Proto-Oncogene Proteins; Pyridines; Rats; Rats, Wistar; Receptors, Platelet-Derived Growth Factor; RNA, Messenger; S Phase; Thymidine; Tritium

1999
Role of phosphoinositide 3-kinase and endocytosis in nerve growth factor-induced extracellular signal-regulated kinase activation via Ras and Rap1.
    Molecular and cellular biology, 2000, Volume: 20, Issue:21

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Blotting, Western; Cell Differentiation; Cell Survival; Cells, Cultured; Chromatography, Affinity; Chromones; Colforsin; Dose-Response Relationship, Drug; Endocytosis; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Ganglia, Spinal; Immunohistochemistry; Luciferases; Microscopy, Electron; Microscopy, Fluorescence; Mitogen-Activated Protein Kinases; Models, Biological; Morpholines; Nerve Growth Factor; PC12 Cells; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-raf; rap1 GTP-Binding Proteins; ras Proteins; Rats; Receptor, trkA; Signal Transduction; Time Factors; Transfection

2000
Evaluation of signal transduction pathways in chemoattractant-induced human monocyte chemotaxis.
    Inflammation, 2001, Volume: 25, Issue:2

    Topics: 1-Methyl-3-isobutylxanthine; Androstadienes; Chemokine CCL2; Chemokine CCL3; Chemokine CCL4; Chemokine CCL5; Chemotactic Factors; Chemotaxis, Leukocyte; Chromones; Colforsin; Flavonoids; Humans; In Vitro Techniques; Macrophage Inflammatory Proteins; Mitogen-Activated Protein Kinases; Monocytes; Morpholines; N-Formylmethionine Leucyl-Phenylalanine; Phosphatidylinositol 3-Kinases; Signal Transduction; Wortmannin

2001
Roles of cAMP in regulation of both MAP kinase and p34(cdc2) kinase activity during meiotic progression, especially beyond the MI stage.
    Molecular reproduction and development, 2002, Volume: 62, Issue:1

    Topics: 1-Methyl-3-isobutylxanthine; Animals; CDC2 Protein Kinase; Cell Nucleus; Cells, Cultured; Chromatography, High Pressure Liquid; Chromones; Colforsin; Cyclic AMP; Female; Meiosis; Mitogen-Activated Protein Kinases; Morpholines; Naphthalenes; Oocytes; Phosphodiesterase Inhibitors; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase C; Swine; Time Factors

2002
Immediate and delayed VEGF-mediated NO synthesis in endothelial cells: role of PI3K, PKC and PLC pathways.
    British journal of pharmacology, 2002, Volume: 137, Issue:7

    Topics: 1-Methyl-3-isobutylxanthine; Androstadienes; Animals; Calcimycin; Calcium; Cattle; Cells, Cultured; Chelating Agents; Chromones; Cyclic GMP; Diterpenes; Dose-Response Relationship, Drug; Egtazic Acid; Endothelial Growth Factors; Endothelium, Vascular; Enzyme Inhibitors; Ginkgolides; Indoles; Intercellular Signaling Peptides and Proteins; Ionophores; Lactones; Lymphokines; Maleimides; Morpholines; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nitroprusside; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Platelet Activating Factor; Platelet Membrane Glycoproteins; Protein Kinase C; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Serine; Signal Transduction; Time Factors; Type C Phospholipases; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors; Wortmannin

2002
Corticotropin-releasing factor (CRF) and related peptides confer neuroprotection via type 1 CRF receptors.
    Neuropharmacology, 2003, Volume: 45, Issue:5

    Topics: 1-Methyl-3-isobutylxanthine; Amphibian Proteins; Amyloid beta-Peptides; Animals; Animals, Newborn; Apoptosis; Blotting, Western; Cell Survival; Cells, Cultured; Cerebellum; Cerebral Cortex; Chromatin; Chromones; Colforsin; Corticotropin-Releasing Hormone; Cyclic AMP; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Glycogen Synthase Kinase 3; Hippocampus; In Situ Nick-End Labeling; Inhibitory Concentration 50; L-Lactate Dehydrogenase; Mitogen-Activated Protein Kinase Kinases; Morpholines; Neurons; Neuroprotective Agents; Peptide Fragments; Peptide Hormones; Peptides; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Pyrimidines; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, Corticotropin-Releasing Hormone; Thionucleotides; Time Factors; Urocortins; Urotensins; Vasodilator Agents

2003
Phosphoinositide 3-kinase is involved in Xenopus and Labrus melanophore aggregation.
    Cellular signalling, 2003, Volume: 15, Issue:12

    Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Adenine; Androstadienes; Animals; Chromones; Cyclic AMP; Cyclic Nucleotide Phosphodiesterases, Type 4; Dose-Response Relationship, Drug; Kinetics; Melanocyte-Stimulating Hormones; Melanophores; Melanosomes; Melatonin; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Morpholines; Norepinephrine; Papaverine; Perciformes; Phosphatidylinositol 3-Kinases; Phosphodiesterase Inhibitors; Phosphoinositide-3 Kinase Inhibitors; Phosphoric Diester Hydrolases; Phosphorylation; Rolipram; Signal Transduction; Wortmannin; Xenopus laevis

2003
cAMP-stimulated Na+ transport in H441 distal lung epithelial cells: role of PKA, phosphatidylinositol 3-kinase, and sgk1.
    American journal of physiology. Lung cellular and molecular physiology, 2004, Volume: 287, Issue:4

    Topics: 1-Methyl-3-isobutylxanthine; Biological Transport; Cell Line; Chromones; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dexamethasone; Enzyme Inhibitors; Epithelial Sodium Channels; Humans; Immediate-Early Proteins; Kinetics; Lung; Morpholines; Nuclear Proteins; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Protein Serine-Threonine Kinases; Respiratory Mucosa; Sodium; Sodium Channels

2004
Modulatory role of phosphoinositide 3-kinase in gastric acid secretion.
    American journal of physiology. Gastrointestinal and liver physiology, 2007, Volume: 293, Issue:3

    Topics: 1-Methyl-3-isobutylxanthine; Aminopyrine; Androstadienes; Animals; Carbachol; Cell Shape; Cells, Cultured; Cholinergic Agonists; Chromones; Cyclic AMP; Dose-Response Relationship, Drug; Epidermal Growth Factor; Gastric Acid; Gastric Mucosa; Histamine; Histamine H2 Antagonists; Morpholines; Mutation; Organ Culture Techniques; Parietal Cells, Gastric; Phosphatidylinositol 3-Kinases; Phosphodiesterase Inhibitors; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Pyrimidinones; Rabbits; Receptors, Histamine H2; Signal Transduction; Time Factors; Transduction, Genetic; Wortmannin

2007
Suppression of α-MSH and IBMX-induced melanogenesis by cordycepin via inhibition of CREB and MITF, and activation of PI3K/Akt and ERK-dependent mechanisms.
    International journal of molecular medicine, 2012, Volume: 29, Issue:1

    Topics: 1-Methyl-3-isobutylxanthine; alpha-MSH; Animals; Cell Line, Tumor; Chromones; Cyclic AMP Response Element-Binding Protein; Deoxyadenosines; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Melanins; Mice; Microphthalmia-Associated Transcription Factor; Monophenol Monooxygenase; Morpholines; Phosphatidylinositol 3-Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt; Signal Transduction

2012
Participation of PI3-kinase/Akt signalling in insulin stimulation of p34cdc2 activation in zebrafish oocyte: phosphodiesterase 3 as a potential downstream target.
    Molecular and cellular endocrinology, 2013, Jul-15, Volume: 374, Issue:1-2

    Topics: 1-Methyl-3-isobutylxanthine; Androstadienes; Animals; Chromones; Cyclin-Dependent Kinase-Activating Kinase; Cyclin-Dependent Kinases; Female; Gene Expression Regulation, Developmental; Hydroxyprogesterones; Insulin; Isoenzymes; Meiosis; Morpholines; Oocytes; Phosphatidylinositol 3-Kinase; Phosphodiesterase 3 Inhibitors; Phosphoric Diester Hydrolases; Phosphorylation; Proto-Oncogene Proteins c-akt; Quinolones; Recombinant Proteins; Signal Transduction; Wortmannin; Zebrafish

2013
Betulinic acid isolated from Vitis amurensis root inhibits 3-isobutyl-1-methylxanthine induced melanogenesis via the regulation of MEK/ERK and PI3K/Akt pathways in B16F10 cells.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2014, Volume: 68

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Betulinic Acid; Cell Line, Tumor; Cell Survival; Chromones; CREB-Binding Protein; Flavonoids; Hyperpigmentation; Interferon Type I; Intramolecular Oxidoreductases; Melanins; Mice; Microphthalmia-Associated Transcription Factor; Mitogen-Activated Protein Kinase Kinases; Morpholines; Oxidoreductases; Pentacyclic Triterpenes; Phosphatidylinositol 3-Kinases; Plant Roots; Pregnancy Proteins; Proto-Oncogene Proteins c-akt; Signal Transduction; Triterpenes; Vitis

2014