1-isoamyl-3-isobutylxanthine has been researched along with 8-phenyltheophylline in 3 studies
| Studies (1-isoamyl-3-isobutylxanthine) | Trials (1-isoamyl-3-isobutylxanthine) | Recent Studies (post-2010) (1-isoamyl-3-isobutylxanthine) | Studies (8-phenyltheophylline) | Trials (8-phenyltheophylline) | Recent Studies (post-2010) (8-phenyltheophylline) |
|---|---|---|---|---|---|
| 8 | 0 | 0 | 518 | 0 | 11 |
| Protein | Taxonomy | 1-isoamyl-3-isobutylxanthine (IC50) | 8-phenyltheophylline (IC50) |
|---|---|---|---|
| Adenosine receptor A3 | Homo sapiens (human) | 1.25 | |
| Adenosine receptor A1 | Rattus norvegicus (Norway rat) | 0.2756 | |
| Adenosine receptor A1 | Bos taurus (cattle) | 0.003 | |
| Adenosine receptor A2a | Homo sapiens (human) | 0.454 | |
| Adenosine receptor A2b | Homo sapiens (human) | 0.3125 | |
| Adenosine receptor A2b | Rattus norvegicus (Norway rat) | 1.1 | |
| Adenosine receptor A1 | Homo sapiens (human) | 1.34 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (66.67) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Daly, JW; Padgett, WL; Shamim, MT; Ukena, D | 1 |
| Butts-Lamb, P; Daly, JW; Padgett, W; Shamim, MT; Waters, J | 1 |
| Jacobson, KA; Kim, HS; Kim, SA; Linden, J; Marshall, MA; Melman, N; Müller, CE | 1 |
3 other study(ies) available for 1-isoamyl-3-isobutylxanthine and 8-phenyltheophylline
| Article | Year |
|---|---|
Effects of 8-phenyl and 8-cycloalkyl substituents on the activity of mono-, di-, and trisubstituted alkylxanthines with substitution at the 1-, 3-, and 7-positions.
Topics: Adenylyl Cyclases; Adipose Tissue; Adrenal Gland Neoplasms; Animals; Blood Platelets; Brain; Caffeine; Chemical Phenomena; Chemistry; Humans; Molecular Structure; Phenylisopropyladenosine; Pheochromocytoma; Rats; Receptors, Purinergic; Structure-Activity Relationship; Theophylline; Tumor Cells, Cultured; Xanthines | 1989 |
1,3-Dialkyl-8-(p-sulfophenyl)xanthines: potent water-soluble antagonists for A1- and A2-adenosine receptors.
Topics: Adenosine; Animals; Cerebral Cortex; In Vitro Techniques; Rats; Receptors, Cell Surface; Receptors, Purinergic; Solubility; Structure-Activity Relationship | 1985 |
Structure-activity relationships at human and rat A2B adenosine receptors of xanthine derivatives substituted at the 1-, 3-, 7-, and 8-positions.
Topics: Animals; Binding, Competitive; Cell Line; Cloning, Molecular; Humans; Ligands; Purinergic P1 Receptor Antagonists; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A2B; Receptors, Purinergic P1; Recombinant Proteins; Structure-Activity Relationship; Xanthines | 2002 |