1-isoamyl-3-isobutylxanthine and 1,3-dipropyl-8-cyclopentylxanthine

1-isoamyl-3-isobutylxanthine has been researched along with 1,3-dipropyl-8-cyclopentylxanthine in 2 studies

Compound Research Comparison

Studies (1-isoamyl-3-isobutylxanthine)	Trials (1-isoamyl-3-isobutylxanthine)	Recent Studies (post-2010) (1-isoamyl-3-isobutylxanthine)	Studies (1,3-dipropyl-8-cyclopentylxanthine)	Trials (1,3-dipropyl-8-cyclopentylxanthine)	Recent Studies (post-2010) (1,3-dipropyl-8-cyclopentylxanthine)
8	0	0	1,301	1	165

Protein Interaction Comparison

Protein	Taxonomy	1,3-dipropyl-8-cyclopentylxanthine (IC50)
Adenosine receptor A1	Rattus norvegicus (Norway rat)	0.0051
Adenosine receptor A3	Rattus norvegicus (Norway rat)	0.0038
Adenosine receptor A2a	Homo sapiens (human)	0.2033
Adenosine receptor A2b	Homo sapiens (human)	0.0234
Adenosine receptor A1	Homo sapiens (human)	0.0083

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	1 (50.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	1 (50.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Daly, JW; Padgett, WL; Shamim, MT; Ukena, D	1
Jacobson, KA; Kim, HS; Kim, SA; Linden, J; Marshall, MA; Melman, N; Müller, CE	1

Other Studies

2 other study(ies) available for 1-isoamyl-3-isobutylxanthine and 1,3-dipropyl-8-cyclopentylxanthine

Article	Year
Effects of 8-phenyl and 8-cycloalkyl substituents on the activity of mono-, di-, and trisubstituted alkylxanthines with substitution at the 1-, 3-, and 7-positions. Journal of medicinal chemistry, 1989, Volume: 32, Issue:6 Topics: Adenylyl Cyclases; Adipose Tissue; Adrenal Gland Neoplasms; Animals; Blood Platelets; Brain; Caffeine; Chemical Phenomena; Chemistry; Humans; Molecular Structure; Phenylisopropyladenosine; Pheochromocytoma; Rats; Receptors, Purinergic; Structure-Activity Relationship; Theophylline; Tumor Cells, Cultured; Xanthines	1989
Structure-activity relationships at human and rat A2B adenosine receptors of xanthine derivatives substituted at the 1-, 3-, 7-, and 8-positions. Journal of medicinal chemistry, 2002, May-23, Volume: 45, Issue:11 Topics: Animals; Binding, Competitive; Cell Line; Cloning, Molecular; Humans; Ligands; Purinergic P1 Receptor Antagonists; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A2B; Receptors, Purinergic P1; Recombinant Proteins; Structure-Activity Relationship; Xanthines	2002

Article

Year

Effects of 8-phenyl and 8-cycloalkyl substituents on the activity of mono-, di-, and trisubstituted alkylxanthines with substitution at the 1-, 3-, and 7-positions.

Journal of medicinal chemistry, 1989, Volume: 32, Issue:6

Topics: Adenylyl Cyclases; Adipose Tissue; Adrenal Gland Neoplasms; Animals; Blood Platelets; Brain; Caffeine; Chemical Phenomena; Chemistry; Humans; Molecular Structure; Phenylisopropyladenosine; Pheochromocytoma; Rats; Receptors, Purinergic; Structure-Activity Relationship; Theophylline; Tumor Cells, Cultured; Xanthines

1989

Structure-activity relationships at human and rat A2B adenosine receptors of xanthine derivatives substituted at the 1-, 3-, 7-, and 8-positions.

Journal of medicinal chemistry, 2002, May-23, Volume: 45, Issue:11

Topics: Animals; Binding, Competitive; Cell Line; Cloning, Molecular; Humans; Ligands; Purinergic P1 Receptor Antagonists; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A2B; Receptors, Purinergic P1; Recombinant Proteins; Structure-Activity Relationship; Xanthines

2002