1-hydroxymethylmidazolam has been researched along with telaprevir in 1 studies
| Studies (1-hydroxymethylmidazolam) | Trials (1-hydroxymethylmidazolam) | Recent Studies (post-2010) (1-hydroxymethylmidazolam) | Studies (telaprevir) | Trials (telaprevir) | Recent Studies (post-2010) (telaprevir) |
|---|---|---|---|---|---|
| 163 | 46 | 49 | 985 | 136 | 835 |
| Protein | Taxonomy | 1-hydroxymethylmidazolam (IC50) | telaprevir (IC50) |
|---|---|---|---|
| NS3 protease | 0.9757 | ||
| Cathepsin L2 | Homo sapiens (human) | 1.35 | |
| Prothrombin | Homo sapiens (human) | 1 | |
| Plasminogen | Homo sapiens (human) | 8.7 | |
| Procathepsin L | Homo sapiens (human) | 3.5 | |
| Cathepsin B | Homo sapiens (human) | 2.3033 | |
| Neutrophil elastase | Homo sapiens (human) | 5.56 | |
| Chymase | Homo sapiens (human) | 0.026 | |
| Cathepsin S | Homo sapiens (human) | 0.3 | |
| Cathepsin K | Homo sapiens (human) | 0.63 | |
| Chymotrypsin-like elastase family member 1 | Homo sapiens (human) | 0.03 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Alves, K; Chandorkar, G; Farmer, HF; Garg, V; Smith, F; van Heeswijk, RP | 1 |
1 trial(s) available for 1-hydroxymethylmidazolam and telaprevir
| Article | Year |
|---|---|
Effect of telaprevir on the pharmacokinetics of midazolam and digoxin.
Topics: Adolescent; Adult; Antiviral Agents; Area Under Curve; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Digoxin; Drug Interactions; Female; Humans; Male; Midazolam; Middle Aged; Oligopeptides; Protease Inhibitors; Young Adult | 2012 |