Compounds > 1-hydroxymethylmidazolam
Page last updated: 2024-09-02

1-hydroxymethylmidazolam and sirolimus

1-hydroxymethylmidazolam has been researched along with sirolimus in 1 studies

Compound Research Comparison

Studies
(1-hydroxymethylmidazolam)		Trials
(1-hydroxymethylmidazolam)		Recent Studies (post-2010)
(1-hydroxymethylmidazolam)		Studies
(sirolimus)		Trials
(sirolimus)		Recent Studies (post-2010) (sirolimus)
163464920,7112,36811,516

Protein Interaction Comparison

ProteinTaxonomy1-hydroxymethylmidazolam (IC50)sirolimus (IC50)
Bile salt export pumpHomo sapiens (human)10
ATP-dependent translocase ABCB1Homo sapiens (human)1.25
Cytochrome P450 3A4Homo sapiens (human)2
Cytochrome P450 2C9 Homo sapiens (human)2
Peptidyl-prolyl cis-trans isomerase FKBP1AMus musculus (house mouse)0.001
Cytochrome P450 2C19Homo sapiens (human)4
Serine/threonine-protein kinase mTORHomo sapiens (human)0.0897
Peptidyl-prolyl cis-trans isomerase FKBP1AHomo sapiens (human)0.0042
Regulatory-associated protein of mTORHomo sapiens (human)0.225
Target of rapamycin complex subunit LST8Homo sapiens (human)0.225
Broad substrate specificity ATP-binding cassette transporter ABCG2Homo sapiens (human)1.9
Solute carrier organic anion transporter family member 1B1Homo sapiens (human)1.1

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bouillaud, E; Cheung, W; Delaney, R; Jappe, A; Urva, S1

Trials

1 trial(s) available for 1-hydroxymethylmidazolam and sirolimus

ArticleYear
A phase I study evaluating the effect of everolimus on the pharmacokinetics of midazolam in healthy subjects.
    Journal of clinical pharmacology, 2013, Volume: 53, Issue:4

    Topics: Adult; Anti-Anxiety Agents; Drug Interactions; Everolimus; Humans; Hypnotics and Sedatives; Immunosuppressive Agents; Male; Midazolam; Middle Aged; Sirolimus; Young Adult

2013