1-hydroxymethylmidazolam has been researched along with simvastatin acid in 1 studies
| Studies (1-hydroxymethylmidazolam) | Trials (1-hydroxymethylmidazolam) | Recent Studies (post-2010) (1-hydroxymethylmidazolam) | Studies (simvastatin acid) | Trials (simvastatin acid) | Recent Studies (post-2010) (simvastatin acid) |
|---|---|---|---|---|---|
| 163 | 46 | 49 | 76 | 23 | 33 |
| Protein | Taxonomy | 1-hydroxymethylmidazolam (IC50) | simvastatin acid (IC50) |
|---|---|---|---|
| 3-hydroxy-3-methylglutaryl-coenzyme A reductase | Rattus norvegicus (Norway rat) | 0.0111 | |
| Solute carrier organic anion transporter family member 1B1 | Homo sapiens (human) | 3.6 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Burhenne, J; Haefeli, WE; Lausecker, B; Mikus, G; Stoll, F; Thomsen, T; Weiss, J | 1 |
1 trial(s) available for 1-hydroxymethylmidazolam and simvastatin acid
| Article | Year |
|---|---|
Reduced exposure variability of the CYP3A substrate simvastatin by dose individualization to CYP3A activity.
Topics: Adult; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Enzyme Inhibitors; Female; Humans; Male; Midazolam; Middle Aged; Ritonavir; Simvastatin | 2013 |