1-hydroxymethylmidazolam has been researched along with ritonavir in 2 studies
| Studies (1-hydroxymethylmidazolam) | Trials (1-hydroxymethylmidazolam) | Recent Studies (post-2010) (1-hydroxymethylmidazolam) | Studies (ritonavir) | Trials (ritonavir) | Recent Studies (post-2010) (ritonavir) |
|---|---|---|---|---|---|
| 163 | 46 | 49 | 5,419 | 1,291 | 2,772 |
| Protein | Taxonomy | 1-hydroxymethylmidazolam (IC50) | ritonavir (IC50) |
|---|---|---|---|
| Solute carrier organic anion transporter family member 2B1 | Homo sapiens (human) | 6.1 | |
| Bile salt export pump | Homo sapiens (human) | 2.085 | |
| ATP-dependent translocase ABCB1 | Homo sapiens (human) | 2.65 | |
| Cytochrome P450 3A4 | Homo sapiens (human) | 0.1623 | |
| Cytochrome P450 2D6 | Homo sapiens (human) | 2.3 | |
| Cytochrome P450 2C9 | Homo sapiens (human) | 2.458 | |
| Gag-Pol polyprotein | Human immunodeficiency virus type 1 (NEW YORK-5 ISOLATE) | 0.067 | |
| Substance-K receptor | Homo sapiens (human) | 2.622 | |
| UDP-glucuronosyltransferase 1A1 | Homo sapiens (human) | 2.35 | |
| Thromboxane-A synthase | Homo sapiens (human) | 0.076 | |
| Multidrug and toxin extrusion protein 2 | Homo sapiens (human) | 4.4 | |
| Multidrug and toxin extrusion protein 1 | Homo sapiens (human) | 2.1933 | |
| Solute carrier organic anion transporter family member 1B3 | Homo sapiens (human) | 4.4 | |
| Solute carrier organic anion transporter family member 1B1 | Homo sapiens (human) | 2 | |
| Protease | Human immunodeficiency virus 1 | 4.9253 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hofmann, C; Patel, A; Riek, M; Schmitt, C; Zwanziger, E | 1 |
| Burhenne, J; Haefeli, WE; Lausecker, B; Mikus, G; Stoll, F; Thomsen, T; Weiss, J | 1 |
1 trial(s) available for 1-hydroxymethylmidazolam and ritonavir
| Article | Year |
|---|---|
Reduced exposure variability of the CYP3A substrate simvastatin by dose individualization to CYP3A activity.
Topics: Adult; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Enzyme Inhibitors; Female; Humans; Male; Midazolam; Middle Aged; Ritonavir; Simvastatin | 2013 |
1 other study(ies) available for 1-hydroxymethylmidazolam and ritonavir
| Article | Year |
|---|---|
Effect of saquinavir-ritonavir on cytochrome P450 3A4 activity in healthy volunteers using midazolam as a probe.
Topics: Adult; Area Under Curve; Cross-Over Studies; Cytochrome P-450 CYP3A; Drug Combinations; Drug Interactions; Female; Half-Life; HIV Protease Inhibitors; Humans; Hypnotics and Sedatives; Male; Midazolam; Prospective Studies; Ritonavir; Saquinavir | 2009 |