Page last updated: 2024-09-02

1-hydroxymethylmidazolam and omeprazole

1-hydroxymethylmidazolam has been researched along with omeprazole in 2 studies

Compound Research Comparison

Studies
(1-hydroxymethylmidazolam)
Trials
(1-hydroxymethylmidazolam)
Recent Studies (post-2010)
(1-hydroxymethylmidazolam)
Studies
(omeprazole)
Trials
(omeprazole)
Recent Studies (post-2010) (omeprazole)
16346499,0852,7371,487

Protein Interaction Comparison

ProteinTaxonomy1-hydroxymethylmidazolam (IC50)omeprazole (IC50)
Mcl-1Homo sapiens (human)3.1448
cGMP-specific 3',5'-cyclic phosphodiesteraseHomo sapiens (human)0.28
Potassium-transporting ATPase alpha chain 1Homo sapiens (human)1.45
Cytochrome P450 2C19Homo sapiens (human)2.315
Potassium-transporting ATPase subunit betaHomo sapiens (human)1.45
WD repeat-containing protein 5Homo sapiens (human)1.7
Glutathione S-transferase omega-1Homo sapiens (human)4.6
Histone-lysine N-methyltransferase 2AHomo sapiens (human)1.7
Muscarinic acetylcholine receptorCavia porcellus (domestic guinea pig)3.8

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Frerichs, VA; Haas, CE; Zaranek, C1
Akamatsu, T; Chida, K; Inui, N; Karayama, M; Namiki, N; Tanaka, S; Uchida, S; Watanabe, H1

Trials

1 trial(s) available for 1-hydroxymethylmidazolam and omeprazole

ArticleYear
Analysis of omeprazole, midazolam and hydroxy-metabolites in plasma using liquid chromatography coupled to tandem mass spectrometry.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2005, Sep-25, Volume: 824, Issue:1-2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Administration, Oral; Aryl Hydrocarbon Hydroxylases; Calibration; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2C19; Humans; Injections, Intravenous; Mass Spectrometry; Midazolam; Mixed Function Oxygenases; Omeprazole; Reproducibility of Results; Time Factors

2005

Other Studies

1 other study(ies) available for 1-hydroxymethylmidazolam and omeprazole

ArticleYear
Chronological effects of rifampicin discontinuation on cytochrome P450 activity in healthy Japanese volunteers, using the cocktail method.
    Clinical pharmacology and therapeutics, 2013, Volume: 94, Issue:6

    Topics: Adult; Antibiotics, Antitubercular; Asian People; Caffeine; Cytochrome P-450 Enzyme System; Drug Interactions; Female; Humans; Imidazoles; Losartan; Male; Midazolam; Omeprazole; Rifampin; Tetrazoles; Theophylline; Time Factors; Withholding Treatment

2013