1-hydroxymethylmidazolam has been researched along with fluconazole in 2 studies
| Studies (1-hydroxymethylmidazolam) | Trials (1-hydroxymethylmidazolam) | Recent Studies (post-2010) (1-hydroxymethylmidazolam) | Studies (fluconazole) | Trials (fluconazole) | Recent Studies (post-2010) (fluconazole) |
|---|---|---|---|---|---|
| 163 | 46 | 49 | 9,343 | 721 | 3,664 |
| Protein | Taxonomy | 1-hydroxymethylmidazolam (IC50) | fluconazole (IC50) |
|---|---|---|---|
| Lanosterol 14-alpha demethylase | Candida albicans SC5314 | 0.1296 | |
| Cytochrome P450 2C9 | Homo sapiens (human) | 9.21 | |
| Sterol 14-alpha demethylase | Trypanosoma cruzi strain CL Brener | 0.88 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ahonen, J; Neuvonen, PJ; Olkkola, KT; Takala, A | 1 |
| Atkins, WM; Isoherranen, N; Paine, MF; Thummel, KE; Yang, J | 1 |
2 other study(ies) available for 1-hydroxymethylmidazolam and fluconazole
| Article | Year |
|---|---|
Interaction between fluconazole and midazolam in intensive care patients.
Topics: Adult; Analysis of Variance; Antifungal Agents; Critical Care; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Interactions; Female; Fluconazole; Follow-Up Studies; Humans; Hypnotics and Sedatives; Infusions, Intravenous; Male; Midazolam; Middle Aged; Mixed Function Oxygenases; Positive-Pressure Respiration; Renal Insufficiency | 1999 |
Evidence of CYP3A allosterism in vivo: analysis of interaction between fluconazole and midazolam.
Topics: Allosteric Regulation; Area Under Curve; Biomarkers; Cytochrome P-450 CYP3A; Drug Interactions; Fluconazole; Humans; Midazolam | 2012 |