Compounds > 1-hydroxymethylmidazolam
Page last updated: 2024-09-02

1-hydroxymethylmidazolam and efavirenz

1-hydroxymethylmidazolam has been researched along with efavirenz in 1 studies

Compound Research Comparison

Studies
(1-hydroxymethylmidazolam)		Trials
(1-hydroxymethylmidazolam)		Recent Studies (post-2010)
(1-hydroxymethylmidazolam)		Studies
(efavirenz)		Trials
(efavirenz)		Recent Studies (post-2010) (efavirenz)
16346493,1106311,611

Protein Interaction Comparison

ProteinTaxonomy1-hydroxymethylmidazolam (IC50)efavirenz (IC50)
Chain A, POL POLYPROTEINHuman immunodeficiency virus 10.2612
Chain A, POL POLYPROTEINHuman immunodeficiency virus 10.2612
Chain B, POL POLYPROTEINHuman immunodeficiency virus 10.2612
Chain A, POL POLYPROTEINHuman immunodeficiency virus 10.2612
Chain B, POL POLYPROTEINHuman immunodeficiency virus 10.2612
Chain A, Pol PolyproteinHuman immunodeficiency virus 10.2612
Chain B, Pol PolyproteinHuman immunodeficiency virus 10.2612
Prothrombin Bos taurus (cattle)0.022
Gag-Pol polyproteinHIV-1 M:B_HXB2R0.1852
Gag-Pol polyproteinHuman immunodeficiency virus type 1 (NEW YORK-5 ISOLATE)0.02
Kappa-type opioid receptorCavia porcellus (domestic guinea pig)0.018
Microsomal triglyceride transfer protein large subunitHomo sapiens (human)0.054
Disintegrin and metalloproteinase domain-containing protein 17Homo sapiens (human)0.004
Envelope glycoprotein gp160 [Cleaved into: Surface protein gp120 Human immunodeficiency virus 10.0035
Reverse transcriptase/RNaseH Human immunodeficiency virus 10.1627
Reverse transcriptase Human immunodeficiency virus 10.0643

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kosugi, Y; Takahashi, J1

Other Studies

1 other study(ies) available for 1-hydroxymethylmidazolam and efavirenz

ArticleYear
Species differences and substrate specificity of CYP3A heteroactivation by efavirenz.
    Xenobiotica; the fate of foreign compounds in biological systems, 2015, Volume: 45, Issue:4

    Topics: Administration, Oral; Alkynes; Animals; Benzoxazines; Cyclopropanes; Cytochrome P-450 CYP3A; Drug Interactions; Haplorhini; Humans; Hydroxylation; Male; Microsomes, Liver; Midazolam; Nifedipine; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Species Specificity; Substrate Specificity; Testosterone

2015