Page last updated: 2024-09-02

1-hydroxymethylmidazolam and diclofenac

1-hydroxymethylmidazolam has been researched along with diclofenac in 2 studies

Compound Research Comparison

Studies
(1-hydroxymethylmidazolam)
Trials
(1-hydroxymethylmidazolam)
Recent Studies (post-2010)
(1-hydroxymethylmidazolam)
Studies
(diclofenac)
Trials
(diclofenac)
Recent Studies (post-2010) (diclofenac)
16346498,8741,8743,616

Protein Interaction Comparison

ProteinTaxonomy1-hydroxymethylmidazolam (IC50)diclofenac (IC50)
Aldo-keto reductase family 1 member B10Homo sapiens (human)1.9
Prostaglandin G/H synthase 1 Bos taurus (cattle)0.003
Prostaglandin G/H synthase 1Ovis aries (sheep)1.3376
Interleukin-8Homo sapiens (human)0.008
Prostaglandin G/H synthase 1Homo sapiens (human)0.0415
Sodium- and chloride-dependent GABA transporter 1Rattus norvegicus (Norway rat)0.5
C-X-C chemokine receptor type 1Homo sapiens (human)0.012
Sodium- and chloride-dependent GABA transporter 2Rattus norvegicus (Norway rat)0.5
Sodium- and chloride-dependent GABA transporter 3Rattus norvegicus (Norway rat)0.5
Prostaglandin G/H synthase 2Homo sapiens (human)0.4165
Prostaglandin G/H synthase 2 Rattus norvegicus (Norway rat)0.5
Sodium- and chloride-dependent betaine transporterRattus norvegicus (Norway rat)0.5
Prostaglandin G/H synthase 2Ovis aries (sheep)1.6867
Prostaglandin G/H synthase 2Mus musculus (house mouse)0.0502
Solute carrier family 22 member 6Homo sapiens (human)4
Prostaglandin G/H synthase 1 Rattus norvegicus (Norway rat)0.5
P2Y purinoceptor 12Rattus norvegicus (Norway rat)0.02

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bush, D; Doss, GA; Franklin, RB; Vincent, S; Xu, S; Zhu, B1
Atzrodt, J; Blankenstein, J; Brasseur, D; Calvo-Vicente, S; Denoux, M; Derdau, V; Lavisse, M; Perard, S; Roy, S; Sandvoss, M; Schofield, J; Zimmermann, J1

Other Studies

2 other study(ies) available for 1-hydroxymethylmidazolam and diclofenac

ArticleYear
Characterization of 1'-hydroxymidazolam glucuronidation in human liver microsomes.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:2

    Topics: Animals; Central Nervous System Agents; Diclofenac; Glucuronides; Glucuronosyltransferase; Humans; Male; Microsomes, Liver; Midazolam; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Sapogenins; Uridine Diphosphate Glucuronic Acid

2008
Synthesis of stable isotope labelled internal standards for drug-drug interaction (DDI) studies.
    Bioorganic & medicinal chemistry, 2012, Sep-15, Volume: 20, Issue:18

    Topics: Cytochrome P-450 Enzyme System; Deuterium Exchange Measurement; Diclofenac; Isotope Labeling; Microwaves; Midazolam; Molecular Structure; Pharmaceutical Preparations; Reference Standards

2012