1-hydroxymethylmidazolam has been researched along with 6 beta-hydroxycortisol in 4 studies
| Studies (1-hydroxymethylmidazolam) | Trials (1-hydroxymethylmidazolam) | Recent Studies (post-2010) (1-hydroxymethylmidazolam) | Studies (6 beta-hydroxycortisol) | Trials (6 beta-hydroxycortisol) | Recent Studies (post-2010) (6 beta-hydroxycortisol) |
|---|---|---|---|---|---|
| 163 | 46 | 49 | 286 | 65 | 51 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Belas, F; Chaudhary, AK; Cvetkovic, M; Dempsey, PJ; Fromm, MF; Kim, RB; Leake, B; Roden, DM; Roden, MM; Wandel, C; Wilkinson, GR; Wood, AJ | 1 |
| Cheng, ZN; Hu, ZY; Wu, D; Zhao, YS | 1 |
| Cheng, ZN; Hu, ZY; Li, XM; Luo, X | 1 |
| Berger, B; Dingemanse, J; Kaufmann, P; Koch, A | 1 |
2 trial(s) available for 1-hydroxymethylmidazolam and 6 beta-hydroxycortisol
| Article | Year |
|---|---|
Evaluation of CYP3A activity in humans using three different parameters based on endogenous cortisol metabolism.
Topics: Clarithromycin; Cross-Over Studies; Cytochrome P-450 CYP3A; Female; Humans; Hydrocortisone; Male; Midazolam; Young Adult | 2009 |
Impact of the Selective Orexin-1 Receptor Antagonist ACT-539313 on the Pharmacokinetics of the CYP3A Probe Drug Midazolam in Healthy Male Subjects.
Topics: Adult; Area Under Curve; Biomarkers; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Drug Administration Schedule; Drug Interactions; Healthy Volunteers; Humans; Hydrocortisone; Male; Midazolam; Middle Aged; Orexin Receptor Antagonists; Orexin Receptors; Young Adult | 2020 |
2 other study(ies) available for 1-hydroxymethylmidazolam and 6 beta-hydroxycortisol
| Article | Year |
|---|---|
Interrelationship between substrates and inhibitors of human CYP3A and P-glycoprotein.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Caco-2 Cells; Cells, Cultured; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Resistance, Multiple; Enzyme Inhibitors; Humans; Male; Mice; Oxidoreductases, N-Demethylating; Pharmacokinetics; Substrate Specificity | 1999 |
Endogenous cortisol 6 beta-hydroxylation clearance is not an accurate probe for overall cytochrome P450 3A phenotyping in humans.
Topics: Administration, Oral; Cytochrome P-450 CYP3A; Female; Humans; Hydrocortisone; Hydroxylation; Male; Midazolam; Phenotype; Time Factors | 2009 |