Compounds > 1-hydroxy-5,8-bis(2-((2-hydroxyethyl)amino)ethylamino)-9,10-anthracenedione
Page last updated: 2024-09-04

1-hydroxy-5,8-bis(2-((2-hydroxyethyl)amino)ethylamino)-9,10-anthracenedione and ametantrone

1-hydroxy-5,8-bis(2-((2-hydroxyethyl)amino)ethylamino)-9,10-anthracenedione has been researched along with ametantrone in 2 studies

*ametantrone: RN given refers to parent cpd; structure [MeSH]

*ametantrone: RN given refers to parent cpd; structure [MeSH]

Compound Research Comparison

Studies
(1-hydroxy-5,8-bis(2-((2-hydroxyethyl)amino)ethylamino)-9,10-anthracenedione)		Trials
(1-hydroxy-5,8-bis(2-((2-hydroxyethyl)amino)ethylamino)-9,10-anthracenedione)		Recent Studies (post-2010)
(1-hydroxy-5,8-bis(2-((2-hydroxyethyl)amino)ethylamino)-9,10-anthracenedione)		Studies
(ametantrone)		Trials
(ametantrone)		Recent Studies (post-2010) (ametantrone)
6039318

Protein Interaction Comparison

ProteinTaxonomy1-hydroxy-5,8-bis(2-((2-hydroxyethyl)amino)ethylamino)-9,10-anthracenedione (IC50)ametantrone (IC50)
DNA topoisomerase 2-betaHomo sapiens (human)0.03

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19901 (50.00)18.7374
1990's1 (50.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Capranico, G; Cera, C; Gatto, B; Palù, G; Palumbo, M; Sissi, C; Uriarte, E; Zagotto, G1
Kharasch, ED; Novak, RF1

Other Studies

2 other study(ies) available for 1-hydroxy-5,8-bis(2-((2-hydroxyethyl)amino)ethylamino)-9,10-anthracenedione and ametantrone

ArticleYear
Peptidyl anthraquinones as potential antineoplastic drugs: synthesis, DNA binding, redox cycling, and biological activity.
    Journal of medicinal chemistry, 1996, Aug-02, Volume: 39, Issue:16

    Topics: Animals; Anthraquinones; Antineoplastic Agents; Cell Division; Circular Dichroism; DNA; DNA Topoisomerases, Type II; Humans; Intercalating Agents; Mice; Mitoxantrone; Molecular Conformation; Molecular Structure; Oxidation-Reduction; Peptides; Thermodynamics; Tumor Cells, Cultured

1996
Inhibitory effects of anthracenedione antineoplastic agents on hepatic and cardiac lipid peroxidation.
    The Journal of pharmacology and experimental therapeutics, 1983, Volume: 226, Issue:2

    Topics: Animals; Anthraquinones; Antineoplastic Agents; Daunorubicin; Doxorubicin; Lipid Peroxides; Liver; Male; Mitoxantrone; Myocardium; Rabbits; Rats; Rats, Inbred Strains

1983