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1-hydroxy-1-phenyl-2-propanone and acetone

1-hydroxy-1-phenyl-2-propanone has been researched along with acetone in 49 studies

Research

Studies (49)

TimeframeStudies, this research(%)All Research%
pre-19905 (10.20)18.7374
1990's4 (8.16)18.2507
2000's27 (55.10)29.6817
2010's11 (22.45)24.3611
2020's2 (4.08)2.80

Authors

AuthorsStudies
Netrval, J; Vojtísek, V1
Bruhn, H; Grötzinger, J; Kula, MR; Pohl, M1
Rogers, PL; Shin, HS; Wang, B1
Agarwal, SC; Basu, SK; Bihari, V; Joshi, AK; Tripathi, CK1
Anderson, BN; Oliver, AL; Roddick, FA1
Breuer, M; Goetz, G; Hauer, B; Iwan, P; Pohl, M1
Breuer, M; Hauer, B; Rogers, P; Rosche, B; Sandford, V2
Kostraby, MM; Smallridge, AJ; Trewhella, MA1
Breuer, M; Hauer, B; Leksawasdi, N; Rogers, P; Rosche, B; Sandford, V1
Breuer, M; Hauer, B; Lingen, B; Pohl, M1
Wen, SZ; Xu, XY; Zhen, SF; Zheng, YM1
Breuer, M; Hauer, B1
Janusz, A; Kirkbride, KP; Megharaj, M; Naidu, R; Perkins, MV; Scott, TL1
Barak, Z; Chipman, DM; Engel, S; Geresh, S; Vyazmensky, M1
Breuer, M; Hauer, B; Rogers, PL; Rosche, B5
HENDLIN, D; SMITH, PF2
BECVAROVA, H; HANC, O1
ERGE, D; GROEGER, D1
Macaulay, JB; Silk, PJ1
Agarwal, SC; Bihari, V; Joshi, AK; Mandwal, AK; Tripathi, CK; Trivedi, PD1
Breuer, M; Chow, YY; Hauer, B; Leksawasdi, N; Rogers, PL; Rosche, B1
Barak, Z; Berkovich, D; Chipman, DM; Engel, S; Merchuk, J; Vyazmensky, M1
Breuer, M; Hauer, B; Rogers, PL; Rosche, B; Satianegara, G1
Barak, Z; Belenky, I; Chipman, DM; Engel, S; Kaplun, A; Kryukov, O; Vinogradov, V; Vyazmensky, M1
Rogers, PL; Rosche, B; Satianegara, G1
Baykal, A; Chakraborty, S; Dodoo, A; Jordan, F1
Breuer, M; Chen, AK; Gunawan, C; Hauer, B; Rogers, PL; Rosche, B; Satianegara, G1
Breuer, M; Gunawan, C; Hauer, B; Rogers, PL; Rosche, B1
Li, W; Qi, H; Wang, Z; Zhang, W; Zhuang, B1
Poppi, RJ; Trevisan, MG1
Liang, R; Liu, Y; Qi, H; Wang, Z; Xu, JH1
Qi, H; Qian, C; Wang, Z; Xu, JH; Xue, Y; Yang, R1
Daugulis, AJ; Khan, TR2
Bar, E; Ben-Shabat, S; Facchini, PJ; Hagel, JM; Kilpatrick, K; Krizevski, R; Levy, A; Lewinsohn, E; Marsolais, F; Shalit, OR; Sitrit, Y1
Andreu, C; Del Olmo, ML1
Kandar, S; Noronha, SB; Suresh, AK1
Demir, AS; Tural, B; Tural, S1
Brodhun, F; Ficner, R; Funk, LM; Loschonsky, S; Meyer, D; Müller, M; Neumann, P; Tittmann, K; Wechsler, C1
Beigi, M; Bonina, F; Gauchenova, E; Müller, M; Pohl, M; Rother, D; Stillger, T; Walter, L; Waltzer, S1
Andreu, C; Lí Del Olmo, M1
Asadollahi, MA; Biria, D; Iranmanesh, E1
Arpanaei, A; Asadollahi, MA; Iranmanesh, E; Seifi, MM1

Reviews

2 review(s) available for 1-hydroxy-1-phenyl-2-propanone and acetone

ArticleYear
Biotransformation for L-ephedrine production.
    Advances in biochemical engineering/biotechnology, 1997, Volume: 56

    Topics: Acetone; Benzaldehydes; Biotransformation; Ephedrine; Industrial Microbiology; Kinetics; Pyruvate Decarboxylase; Yeasts

1997
Factors affecting the production of L-phenylacetylcarbinol by yeast: a case study.
    Advances in microbial physiology, 1999, Volume: 41

    Topics: Acetone; Alcohol Dehydrogenase; Benzaldehydes; Biomass; Bioreactors; Biotechnology; Candida; Culture Media; Enzymes, Immobilized; Ephedrine; Fermentation; Pyruvate Decarboxylase; Saccharomyces cerevisiae

1999

Other Studies

47 other study(ies) available for 1-hydroxy-1-phenyl-2-propanone and acetone

ArticleYear
Effect of pyruvate decarboxylase activity and of pyruvate concentration on the production of 1-hydroxy-1-phenylpropanone in Saccharomyces carlsbergensis.
    Folia microbiologica, 1982, Volume: 27, Issue:3

    Topics: Acetone; Carboxy-Lyases; Kinetics; Pyruvate Decarboxylase; Pyruvates; Pyruvic Acid; Saccharomyces

1982
The replacement of Trp392 by alanine influences the decarboxylase/carboligase activity and stability of pyruvate decarboxylase from Zymomonas mobilis.
    European journal of biochemistry, 1995, Dec-01, Volume: 234, Issue:2

    Topics: Acetone; Base Sequence; Decarboxylation; Enzyme Stability; Molecular Sequence Data; Mutagenesis, Site-Directed; Pyruvate Decarboxylase; Thiamine Pyrophosphate; Zymomonas

1995
Production of L-phenylacetylcarbinol by free and immobilized yeast cells.
    Indian journal of experimental biology, 1997, Volume: 35, Issue:8

    Topics: Acetone; Biotransformation; Cells, Immobilized; Saccharomyces cerevisiae

1997
Continuous production of (R)-phenylacetylcarbinol in an enzyme-membrane reactor using a potent mutant of pyruvate decarboxylase from Zymomonas mobilis.
    Biotechnology and bioengineering, 2001, Aug-20, Volume: 74, Issue:4

    Topics: Acetaldehyde; Acetone; Benzaldehydes; Biomass; Bioreactors; Biotransformation; Decarboxylation; Enzyme Stability; Ephedrine; Fermentation; Hydrogen-Ion Concentration; Industrial Microbiology; Kinetics; Membranes, Artificial; Micropore Filters; Mutation; Pyruvate Decarboxylase; Saccharomyces cerevisiae; Zymomonas

2001
Biotransformation of benzaldehyde into (R)-phenylacetylcarbinol by filamentous fungi or their extracts.
    Applied microbiology and biotechnology, 2001, Volume: 57, Issue:3

    Topics: Acetone; Benzaldehydes; Biomass; Biotransformation; Fungi; Pyruvic Acid

2001
Yeast-mediated preparation of l-PAC in an organic solvent.
    Biotechnology and bioengineering, 2002, Mar-30, Volume: 77, Issue:7

    Topics: Acetone; Benzaldehydes; Buffers; Chromatography, Gas; Ethanol; Fermentation; Magnetic Resonance Imaging; Pyruvic Acid; Saccharomyces cerevisiae

2002
Enzymatic (R)-phenylacetylcarbinol production in benzaldehyde emulsions.
    Applied microbiology and biotechnology, 2002, Volume: 60, Issue:1-2

    Topics: Acetone; Benzaldehydes; Biotransformation; Ethanol; Fermentation; Hydrogen-Ion Concentration; Industrial Microbiology; Kinetics; Rhizopus; Temperature

2002
High-throughput assay of ( R)-phenylacetylcarbinol synthesized by pyruvate decarboxylase.
    Analytical and bioanalytical chemistry, 2002, Volume: 374, Issue:6

    Topics: Acetone; Photometry; Pyruvate Decarboxylase; Stereoisomerism

2002
[Studies on the semi-biosynthesis of L-ephedrine (I). Studies on the biosynthesis of L-phenyl acetyl carbinol].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2001, Volume: 26, Issue:2

    Topics: Acetone; Ephedrine; Prodrugs; Saccharomyces cerevisiae

2001
Detection of aromatic alpha-hydroxyketones with tetrazolium salts.
    Methods in molecular biology (Clifton, N.J.), 2003, Volume: 230

    Topics: Acetone; Cloning, Molecular; Colorimetry; Directed Molecular Evolution; Escherichia coli; Genetic Variation; Indicators and Reagents; Ketones; Kinetics; Pyruvate Decarboxylase; Reproducibility of Results; Saccharomyces cerevisiae; Sensitivity and Specificity; Tetrazolium Salts; Zymomonas

2003
Microbial degradation of illicit drugs, their precursors, and manufacturing by-products: implications for clandestine drug laboratory investigation and environmental assessment.
    Forensic science international, 2003, Jun-24, Volume: 134, Issue:1

    Topics: 2-Propanol; Acetone; Biodegradation, Environmental; Central Nervous System Stimulants; Forensic Medicine; Gas Chromatography-Mass Spectrometry; Magnetic Resonance Spectroscopy; Methamphetamine; Soil; Soil Microbiology

2003
Acetohydroxyacid synthase: a new enzyme for chiral synthesis of R-phenylacetylcarbinol.
    Biotechnology and bioengineering, 2003, Sep-30, Volume: 83, Issue:7

    Topics: Acetolactate Synthase; Acetone; Benzaldehydes; Binding Sites; Catalysis; Escherichia coli; Fermentation; Isoenzymes; Molecular Structure; Pyruvic Acid; Stereoisomerism; Temperature; Time Factors

2003
Screening of yeasts for cell-free production of (R)-phenylacetylcarbinol.
    Biotechnology letters, 2003, Volume: 25, Issue:11

    Topics: Acetaldehyde; Acetone; Aldehydes; Benzaldehydes; Cell-Free System; Drug Evaluation, Preclinical; Enzyme Activation; Pyruvate Decarboxylase; Species Specificity; Yeasts

2003
Increased pyruvate efficiency in enzymatic production of (R)-phenylacetylcarbinol.
    Biotechnology letters, 2003, Volume: 25, Issue:11

    Topics: Acetaldehyde; Acetoin; Acetone; Biotransformation; Candida; Coenzymes; Enzyme Activation; Magnesium; Pyruvate Decarboxylase; Pyruvic Acid; Quality Control; Rhizopus; Species Specificity; Substrate Specificity; Temperature

2003
Mechanism of phenylacetylcarbinol synthesis by yeast.
    Journal of bacteriology, 1953, Volume: 65, Issue:4

    Topics: Acetone; Alcohols; Saccharomyces cerevisiae; Yeast, Dried; Yeasts

1953
Further studies on phenylacetylcarbinol synthesis by yeast.
    Applied microbiology, 1954, Volume: 2, Issue:5

    Topics: Acetone; Alcohols; Saccharomyces cerevisiae; Yeast, Dried; Yeasts

1954
Production of phenylacetylcarbinol by various yeast species.
    Folia microbiologica, 1963, Volume: 8

    Topics: Acetone; Alcohols; Aldehydes; Carboxy-Lyases; Saccharomyces cerevisiae; Yeasts

1963
[ON THE ANALYSIS OF PHENYLACETYLCARBINOL, AN INTERMEDIATE PRODUCT IN EPHEDRINE SYNTHESIS].
    Die Pharmazie, 1965, Volume: 20

    Topics: Acetone; Alcohols; Chemistry, Pharmaceutical; Ephedrine; Pharmacy; Research

1965
Stereoselective biosynthesis of chloroarylpropane diols by the basidiomycete Bjerkandera adusta: exploring the roles of amino acids, pyruvate, glycerol and phenyl acetyl carbinol.
    FEMS microbiology letters, 2003, Nov-07, Volume: 228, Issue:1

    Topics: Acetone; Amino Acids; Basidiomycota; Benzaldehydes; Glucose; Glycerol; Hydrocarbons, Aromatic; Hydrocarbons, Chlorinated; Molecular Conformation; Pyruvic Acid

2003
Production of L-phenylacetyl carbinol by immobilized cells of Saccharomyces cerevisiae.
    Biotechnology letters, 2004, Volume: 26, Issue:3

    Topics: Acetone; Benzaldehydes; Bioreactors; Biotransformation; Catalysis; Cell Culture Techniques; Cell Division; Cells, Immobilized; Saccharomyces cerevisiae

2004
Biphasic aqueous/organic biotransformation of acetaldehyde and benzaldehyde by Zymomonas mobilis pyruvate decarboxylase.
    Biotechnology and bioengineering, 2004, Jun-30, Volume: 86, Issue:7

    Topics: Acetaldehyde; Acetone; Benzaldehydes; Biotransformation; Pyruvate Decarboxylase; Solvents; Zymomonas

2004
Kinetic analysis and modelling of enzymatic (R)-phenylacetylcarbinol batch biotransformation process.
    Journal of biotechnology, 2004, Jul-15, Volume: 111, Issue:2

    Topics: Acetone; Benzaldehydes; Bioreactors; Biotransformation; Candida; Computer Simulation; Enzyme Activation; Kinetics; Models, Chemical; Pyruvate Decarboxylase; Pyruvic Acid

2004
Role of pyruvate in enhancing pyruvate decarboxylase stability towards benzaldehyde.
    Journal of biotechnology, 2005, Jan-12, Volume: 115, Issue:1

    Topics: Acetone; Benzaldehydes; Candida; Catalysis; Enzyme Activation; Enzyme Stability; Glycerol; Hydrogen-Ion Concentration; Kinetics; Pyruvate Decarboxylase; Pyruvic Acid

2005
Column flow reactor using acetohydroxyacid synthase I from Escherichia coli as catalyst in continuous synthesis of R-phenylacetyl carbinol.
    Biotechnology and bioengineering, 2005, Mar-20, Volume: 89, Issue:6

    Topics: Acetolactate Synthase; Acetone; Bioreactors; Catalysis; Cellulose; Enzymes, Immobilized; Escherichia coli; Protein Structure, Tertiary

2005
(R)-phenylacetylcarbinol production in aqueous/organic two-phase systems using partially purified pyruvate decarboxylase from Candida utilis.
    Biotechnology and bioengineering, 2005, Jul-20, Volume: 91, Issue:2

    Topics: Acetone; Benzaldehydes; Candida; Enzyme Activation; Enzyme Stability; Feasibility Studies; Phase Transition; Pyruvate Decarboxylase; Pyruvic Acid; Water

2005
Cells of Candida utilis for in vitro (R)-phenylacetylcarbinol production in an aqueous/octanol two-phase reactor.
    Biotechnology letters, 2005, Volume: 27, Issue:8

    Topics: Acetone; Benzaldehydes; Bioreactors; Biotransformation; Candida; Cell Division; Chromatography, High Pressure Liquid; Glucose; Heptanol; Octanols; Pyruvic Acid

2005
Enzymatic (R)-phenylacetylcarbinol production in a benzaldehyde emulsion system with Candida utilis cells.
    Applied microbiology and biotechnology, 2006, Volume: 70, Issue:2

    Topics: Acetone; Benzaldehydes; Candida; Enzyme Stability; Kinetics; Pyruvate Decarboxylase; Pyruvic Acid; Temperature

2006
Acetohydroxyacid synthase isozyme I from Escherichia coli has unique catalytic and regulatory properties.
    Biochimica et biophysica acta, 2006, Volume: 1760, Issue:3

    Topics: Acetolactate Synthase; Acetone; Cloning, Molecular; Escherichia coli; Escherichia coli Proteins; Feedback, Physiological; Isoenzymes; Isomerism; Kinetics; Valine

2006
Comparative studies on enzyme preparations and role of cell components for (R)-phenylacetylcarbinol production in a two-phase biotransformation.
    Biotechnology and bioengineering, 2006, Aug-20, Volume: 94, Issue:6

    Topics: Acetone; Biotransformation; Candida; Octanols; Pyruvate Decarboxylase; Subcellular Fractions; Water

2006
Synthesis with good enantiomeric excess of both enantiomers of alpha-ketols and acetolactates by two thiamin diphosphate-dependent decarboxylases.
    Bioorganic chemistry, 2006, Volume: 34, Issue:6

    Topics: Acetone; Binding Sites; Carboxy-Lyases; Escherichia coli Proteins; Ketone Oxidoreductases; Ketones; Lactates; Mutation, Missense; Pyruvate Decarboxylase; Pyruvic Acid; Saccharomyces cerevisiae Proteins; Stereoisomerism; Thiamine Pyrophosphate

2006
Yeast pyruvate decarboxylases: variation in biocatalytic characteristics for (R)-phenylacetylcarbinol production.
    FEMS yeast research, 2007, Volume: 7, Issue:1

    Topics: Acetone; Benzaldehydes; Candida; Catalysis; Industrial Microbiology; Kluyveromyces; Pyruvate Decarboxylase; Pyruvates; Saccharomyces cerevisiae

2007
Improved (R)-phenylacetylcarbinol production with Candida utilis pyruvate decarboxylase at decreased organic to aqueous phase volume ratios.
    Biotechnology letters, 2008, Volume: 30, Issue:2

    Topics: Acetone; Candida; Chemical Fractionation; Octanols; Pyruvate Decarboxylase; Solubility; Temperature; Water

2008
Production of L-phenylacetylcarbinol by microbial transformation in polyethylene glycol-induced cloud point system.
    Applied microbiology and biotechnology, 2008, Volume: 78, Issue:2

    Topics: Acetaldehyde; Acetone; Benzaldehydes; Biotransformation; Culture Media; Glucose; Polyethylene Glycols; Saccharomyces cerevisiae

2008
Direct determination of ephedrine intermediate in a biotransformation reaction using infrared spectroscopy and PLS.
    Talanta, 2008, May-30, Volume: 75, Issue:4

    Topics: Acetone; Biotransformation; Calibration; Chalcones; Ephedrine; Gas Chromatography-Mass Spectrometry; Kinetics; Least-Squares Analysis; Reproducibility of Results; Saccharomyces cerevisiae; Spectrophotometry, Infrared; Stereoisomerism

2008
A closed concept of extractive whole cell microbial transformation of benzaldehyde into L-phenylacetylcarbinol by Saccharomyces cerevisiae in novel polyethylene-glycol-induced cloud-point system.
    Applied biochemistry and biotechnology, 2010, Volume: 160, Issue:6

    Topics: Acetone; Benzaldehydes; Biotechnology; Biotransformation; Emulsions; Phase Transition; Polyethylene Glycols; Saccharomyces cerevisiae; Solvents; Surface-Active Agents; Temperature

2010
Investigation of extractive microbial transformation in nonionic surfactant micelle aqueous solution using response surface methodology.
    Applied microbiology and biotechnology, 2010, Volume: 85, Issue:3

    Topics: Acetone; Benzaldehydes; Biotechnology; Biotransformation; Glucose; Micelles; Models, Theoretical; Solutions; Surface-Active Agents

2010
Application of solid-liquid TPPBs to the production of L-phenylacetylcarbinol from benzaldehyde using Candida utilis.
    Biotechnology and bioengineering, 2010, Nov-01, Volume: 107, Issue:4

    Topics: Acetone; Benzaldehydes; Benzyl Alcohol; Bioreactors; Biotechnology; Biotransformation; Candida; Glucose; Polyesters

2010
The effects of polymer phase ratio and feeding strategy on solid-liquid TPPBs for the production of L-phenylacetylcarbinol from benzaldehyde using Candida utilis.
    Biotechnology letters, 2011, Volume: 33, Issue:1

    Topics: Acetone; Benzaldehydes; Biotechnology; Candida; Microspheres; Polyesters

2011
Benzaldehyde is a precursor of phenylpropylamino alkaloids as revealed by targeted metabolic profiling and comparative biochemical analyses in Ephedra spp.
    Phytochemistry, 2012, Volume: 81

    Topics: Acetone; Alcohol Oxidoreductases; Alkaloids; Benzaldehydes; Enzyme Activation; Ephedra; Ephedrine; Metabolome; Plant Proteins; Plant Stems; Propylamines; Pyruvic Acid; Solid Phase Microextraction; Solubility; Species Specificity

2012
Potential of some yeast strains in the stereoselective synthesis of (R)-(-)-phenylacetylcarbinol and (S)-(+)-phenylacetylcarbinol and their reduced 1,2-dialcohol derivatives.
    Applied microbiology and biotechnology, 2014, Volume: 98, Issue:13

    Topics: Acetone; Biotransformation; Culture Media; Hydrogen-Ion Concentration; Kluyveromyces; Propylene Glycol; Saccharomycetales; Stereoisomerism; Temperature; Time Factors

2014
(R)-PAC biosynthesis in [BMIM][PF₆]/aqueous biphasic system using Saccharomyces cerevisiae BY4741 cells.
    Applied biochemistry and biotechnology, 2015, Volume: 175, Issue:4

    Topics: Acetone; Benzaldehydes; Bioreactors; Biotransformation; Factor Analysis, Statistical; Fermentation; Glucose; Imidazoles; Industrial Microbiology; Ionic Liquids; Pyruvate Decarboxylase; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins

2015
Heterofunctional Magnetic Metal-Chelate-Epoxy Supports for the Purification and Covalent Immobilization of Benzoylformate Decarboxylase From Pseudomonas Putida and Its Carboligation Reactivity.
    Chirality, 2015, Volume: 27, Issue:9

    Topics: Acetaldehyde; Acetone; Benzaldehydes; Benzoin; Biocatalysis; Carboxy-Lyases; Chelating Agents; Cobalt; Enzymes, Immobilized; Epoxy Compounds; Histidine; Magnets; Pseudomonas putida; Stereoisomerism

2015
Tuning and Switching Enantioselectivity of Asymmetric Carboligation in an Enzyme through Mutational Analysis of a Single Hot Spot.
    Chembiochem : a European journal of chemical biology, 2015, Volume: 16, Issue:18

    Topics: Acetone; Binding Sites; Fatty Alcohols; Molecular Dynamics Simulation; Mutagenesis; Protein Structure, Tertiary; Pyruvate Decarboxylase; Stereoisomerism; Zymomonas

2015
Regio- and Stereoselective Aliphatic-Aromatic Cross-Benzoin Reaction: Enzymatic Divergent Catalysis.
    Chemistry (Weinheim an der Bergstrasse, Germany), 2016, Sep-19, Volume: 22, Issue:39

    Topics: Acetobacter; Acetone; Aldehyde-Lyases; Aldehydes; Benzoin; Biocatalysis; Carboxy-Lyases; Chemistry Techniques, Synthetic; Hydroxypropiophenone; Lactococcus lactis; Pseudomonas fluorescens; Pseudomonas putida; Stereoisomerism; Thiamine Pyrophosphate

2016
Biotransformation using halotolerant yeast in seawater: a sustainable strategy to produce R-(-)-phenylacetylcarbinol.
    Applied microbiology and biotechnology, 2018, Volume: 102, Issue:11

    Topics: Acetone; Ascomycota; Biotransformation; Prodrugs; Seawater; Technology, Pharmaceutical

2018
Improving l-phenylacetylcarbinol production in Saccharomyces cerevisiae by in silico aided metabolic engineering.
    Journal of biotechnology, 2020, Jan-20, Volume: 308

    Topics: Acetone; Benzaldehydes; Computer Simulation; Fungal Proteins; Gene Deletion; Glucose; Metabolic Engineering; Pyruvate Decarboxylase; Saccharomyces cerevisiae

2020
Biotransformation of benzaldehyde into L-phenylacetylcarbinol using magnetic nanoparticles-coated yeast cells.
    Biotechnology letters, 2020, Volume: 42, Issue:4

    Topics: Acetone; Batch Cell Culture Techniques; Benzaldehydes; Biocatalysis; Biotransformation; Magnetite Nanoparticles; Microscopy, Electron, Transmission; Particle Size; Powder Diffraction; Saccharomyces cerevisiae; X-Ray Diffraction

2020