Page last updated: 2024-09-02

1-hexadecyl-2-acetyl-glycero-3-phosphocholine and yohimbine

1-hexadecyl-2-acetyl-glycero-3-phosphocholine has been researched along with yohimbine in 8 studies

Compound Research Comparison

Studies
(1-hexadecyl-2-acetyl-glycero-3-phosphocholine)
Trials
(1-hexadecyl-2-acetyl-glycero-3-phosphocholine)
Recent Studies (post-2010)
(1-hexadecyl-2-acetyl-glycero-3-phosphocholine)
Studies
(yohimbine)
Trials
(yohimbine)
Recent Studies (post-2010) (yohimbine)
9,1561875525,893253532

Protein Interaction Comparison

ProteinTaxonomy1-hexadecyl-2-acetyl-glycero-3-phosphocholine (IC50)yohimbine (IC50)
Alpha-2A adrenergic receptorHomo sapiens (human)0.0353
Cytochrome P450 2D6Homo sapiens (human)1.02
D(2) dopamine receptorHomo sapiens (human)2.06
Alpha-1B adrenergic receptorRattus norvegicus (Norway rat)1.3
Alpha-2B adrenergic receptorHomo sapiens (human)0.0428
Alpha-2C adrenergic receptorHomo sapiens (human)0.0466
5-hydroxytryptamine receptor 1ARattus norvegicus (Norway rat)0.126
Alpha-2B adrenergic receptorRattus norvegicus (Norway rat)0.0682
Alpha-2C adrenergic receptorRattus norvegicus (Norway rat)0.0682
Alpha-2A adrenergic receptorRattus norvegicus (Norway rat)0.0682
Alpha-1D adrenergic receptorRattus norvegicus (Norway rat)1.3
Alpha-1D adrenergic receptorHomo sapiens (human)1.013
5-hydroxytryptamine receptor 1BRattus norvegicus (Norway rat)0.126
5-hydroxytryptamine receptor 2BHomo sapiens (human)0.074
Alpha-1A adrenergic receptorRattus norvegicus (Norway rat)1.3
5-hydroxytryptamine receptor 6Homo sapiens (human)1.689

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19905 (62.50)18.7374
1990's1 (12.50)18.2507
2000's1 (12.50)29.6817
2010's1 (12.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Carmody, LC; Dandapani, S; Donckele, E; Feng, Y; Fernandez, C; Germain, AR; Gupta, PB; Lander, ES; Morgan, B; Munoz, B; Nag, PP; Palmer, M; Perez, JR; Schreiber, SL; Verplank, L1
Baldenkov, GN; Grigorian, GIu; Mazaev, AV; Negresku, EV; Tkachuk, VA1
Calixto, JB; Trebien, HA1
Fouque, F; Parini, A; Schattner, M; Touqui, L; Vargaftig, BB1
Fouque, F; Vargaftig, BB1
Goldenberg, MM; Meurer, RD1
Flores, NA; Goulielmos, NV; Seghatchian, MJ; Sheridan, DJ1
Rasheed, H; Saeed, SA1

Other Studies

8 other study(ies) available for 1-hexadecyl-2-acetyl-glycero-3-phosphocholine and yohimbine

ArticleYear
Cinnamides as selective small-molecule inhibitors of a cellular model of breast cancer stem cells.
    Bioorganic & medicinal chemistry letters, 2013, Mar-15, Volume: 23, Issue:6

    Topics: Amides; Breast Neoplasms; Cell Line, Tumor; Drug Screening Assays, Antitumor; Female; Humans; Neoplastic Stem Cells; Small Molecule Libraries; Structure-Activity Relationship

2013
[Biochemical features of platelet alpha2-adrenergic receptors and their connection with an increase in concentration of intracellular Ca2+].
    Biokhimiia (Moscow, Russia), 1989, Volume: 54, Issue:6

    Topics: Blood Platelets; Calcium; Cyclic AMP; Depression, Chemical; Epinephrine; Humans; Norepinephrine; Phentolamine; Platelet Activating Factor; Prazosin; Propranolol; Receptors, Adrenergic, alpha; Serotonin; Stimulation, Chemical; Vasopressins; Yohimbine

1989
Pharmacological evaluation of rat paw oedema induced by Bothrops jararaca venom.
    Agents and actions, 1989, Volume: 26, Issue:3-4

    Topics: Animals; Captopril; Crotalid Venoms; Dexamethasone; Edema; Hot Temperature; Indomethacin; Male; Masoprocol; Platelet Activating Factor; Prazosin; Quinacrine; Rats; Rats, Inbred Strains; Reference Values; Yohimbine

1989
Selective inhibition of adrenaline-induced human platelet aggregation by the structurally related Paf antagonist Ro 19-3704.
    British journal of pharmacology, 1989, Volume: 96, Issue:4

    Topics: 5-Hydroxytryptophan; Binding, Competitive; Diterpenes; Drug Synergism; Epinephrine; Ginkgolides; Glyceryl Ethers; Humans; In Vitro Techniques; Lactones; Morpholines; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Thiazoles; Yohimbine

1989
Triggering by Paf-acether and adrenaline of cyclo-oxygenase-independent platelet aggregation.
    British journal of pharmacology, 1984, Volume: 83, Issue:3

    Topics: Adenosine Triphosphate; Aspirin; Blood Platelets; Cyclooxygenase Inhibitors; Drug Synergism; Epinephrine; Humans; In Vitro Techniques; Platelet Activating Factor; Platelet Aggregation; Serotonin; Thrombin; Yohimbine

1984
A pharmacologic analysis of the action of platelet-activating factor in the induction of hindpaw edema in the rat.
    Prostaglandins, 1984, Volume: 28, Issue:2

    Topics: Animals; Carrageenan; Dexamethasone; Dose-Response Relationship, Drug; Edema; Hindlimb; Indomethacin; Male; Muscles; Phentolamine; Platelet Activating Factor; Rats; Rats, Inbred Strains; Regional Blood Flow; Theophylline; Verapamil; Yohimbine

1984
Myocardial ischaemia induces platelet activation with adverse electrophysiological and arrhythmogenic effects.
    Cardiovascular research, 1994, Volume: 28, Issue:11

    Topics: Animals; Arrhythmias, Cardiac; Aspirin; Biphenyl Compounds; Blood Platelets; Colforsin; Diterpenes; Electrophysiology; Ginkgolides; Guinea Pigs; Heart; Heptanoic Acids; Lactones; Male; Myocardial Ischemia; Oxidopamine; Platelet Activating Factor; Platelet Activation; Platelet Aggregation Inhibitors; Receptors, Thromboxane; Yohimbine

1994
Calcium-dependent synergistic interaction of platelet activating factor and epinephrine in human platelet aggregation.
    Acta pharmacologica Sinica, 2003, Volume: 24, Issue:1

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Azepines; Calcium Channel Blockers; Cyclooxygenase Inhibitors; Drug Synergism; Epinephrine; Flurbiprofen; Humans; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Signal Transduction; Triazoles; Verapamil; Yohimbine

2003