1-hexadecyl-2-acetyl-glycero-3-phosphocholine has been researched along with wortmannin in 24 studies
| Studies (1-hexadecyl-2-acetyl-glycero-3-phosphocholine) | Trials (1-hexadecyl-2-acetyl-glycero-3-phosphocholine) | Recent Studies (post-2010) (1-hexadecyl-2-acetyl-glycero-3-phosphocholine) | Studies (wortmannin) | Trials (wortmannin) | Recent Studies (post-2010) (wortmannin) |
|---|---|---|---|---|---|
| 9,156 | 187 | 552 | 4,066 | 2 | 726 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 11 (45.83) | 18.2507 |
| 2000's | 12 (50.00) | 29.6817 |
| 2010's | 1 (4.17) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bach, MK; Brashler, JR; Petzold, EN; Sanders, ME | 1 |
| Ferby, IM; Kume, K; Sakanaka, C; Shimizu, T; Waga, I | 1 |
| Ferby, IM; Hoshino, M; Kume, K; Shimizu, T; Waga, I | 1 |
| Duronio, V; Ettinger, SL; Lauener, RW | 1 |
| Ferby, I; Kume, K; Sakanaka, C; Shimizu, T; Waga, I | 1 |
| Saeed, SA; Shah, BH | 1 |
| Coffer, PJ; Geijsen, N; Koenderman, L; Lammers, JW; M'rabet, L; Maikoe, T; Raaijmakers, JA; Schweizer, RC | 1 |
| Gilani, AH; Nawaz, Z; Saeed, SA; Shah, BH; Shamim, G | 1 |
| Bruyneel, E; Chastre, E; Gespach, C; Kotelevets, L; Mareel, M; Myssiakine, E; Noë, V | 1 |
| Duronio, V; Lauener, RW; Salari, H; Sayed, MR; Stevens, CM | 1 |
| Fukunaga, K; Miyamoto, E; Miyazaki, K; Munir, I; Okamura, H | 1 |
| Boetticher, E; Jacobs, B; Leff, AR; Muñoz, NM; Sano, A; Sano, H; Subbaraman, R; Zhu, X | 1 |
| Bazan, NG; Bernatchez, PN; Gélinas, DS; Rollin, S; Sirois, MG | 1 |
| Slomiany, A; Slomiany, BL | 4 |
| Cahana, A; Chandrakanthan, V; Ishii, S; Lu, DP; O'Neill, C | 1 |
| Chan, JS; Filep, JG; József, L; Khreiss, T | 1 |
| Alteraifi, AM; Chodniewicz, D; Zhelev, DV | 1 |
| Chen, LW; Hsu, CM; Lin, MW | 1 |
| Dent, G; Djukanovic, R; Gray, BC; Harb, Z; Mishra, RK; Scaife, JE | 1 |
| Galanopoulou, D; Gountopoulou, A; Leondaritis, G; Mavri-Vavayanni, M | 1 |
| Im, SY; Kim, HA; Kim, KJ; Lee, HK; Seo, KH | 1 |
24 other study(ies) available for 1-hexadecyl-2-acetyl-glycero-3-phosphocholine and wortmannin
| Article | Year |
|---|---|
Superoxide production by human eosinophils can be inhibited in an agonist-selective manner.
Topics: Alkaloids; Androstadienes; Carbazoles; Eosinophils; Humans; Immunoglobulin G; Indole Alkaloids; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Platelet Activating Factor; Protein Kinase C; Sphingosine; Staurosporine; Superoxides; Tetradecanoylphorbol Acetate; Wortmannin; Zymosan | 1992 |
Wortmannin inhibits mitogen-activated protein kinase activation induced by platelet-activating factor in guinea pig neutrophils.
Topics: Androstadienes; Animals; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Egtazic Acid; Enzyme Activation; Female; Guinea Pigs; In Vitro Techniques; Kinetics; Neutrophils; Phosphatidylinositol 3-Kinases; Phosphotransferases (Alcohol Group Acceptor); Platelet Activating Factor; Tetradecanoylphorbol Acetate; Time Factors; Wortmannin | 1994 |
Wortmannin inhibits mitogen-activated protein kinase activation by platelet-activating factor through a mechanism independent of p85/p110-type phosphatidylinositol 3-kinase.
Topics: Androstadienes; Animals; Azepines; Calcium-Calmodulin-Dependent Protein Kinases; Cattle; Enzyme Activation; Enzyme Inhibitors; Mice; Naphthalenes; Phosphatidylinositol 3-Kinases; Phosphotransferases (Alcohol Group Acceptor); Platelet Activating Factor; Transfection; Wortmannin | 1996 |
Protein kinase C delta specifically associates with phosphatidylinositol 3-kinase following cytokine stimulation.
Topics: Androstadienes; Animals; Blood Platelets; Cell Line; Chromones; Cytokines; Enzyme Inhibitors; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Interleukin-3; Interleukin-5; Isoenzymes; Leukemia, Basophilic, Acute; Leukemia, Erythroblastic, Acute; Morpholines; Phosphatidylinositol 3-Kinases; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Phosphotyrosine; Platelet Activating Factor; Protein Binding; Protein Kinase C; Protein Kinase C-delta; Rabbits; Rats; Receptors, IgE; Recombinant Proteins; Tumor Cells, Cultured; Wortmannin | 1996 |
PAF-induced MAPK activation is inhibited by wortmannin in neutrophils and macrophages.
Topics: Androstadienes; Animals; Calcium; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Enzyme Inhibitors; Guinea Pigs; In Vitro Techniques; Macrophages; Neutrophils; Platelet Activating Factor; Wortmannin | 1996 |
Diversity of agonist-mediated signal transduction pathways in human platelets.
Topics: Adenosine Diphosphate; Androstadienes; Arachidonic Acid; Blood Platelets; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Epinephrine; Humans; Phosphoinositide-3 Kinase Inhibitors; Platelet Activating Factor; Platelet Aggregation; Serotonin; Signal Transduction; Wortmannin | 1997 |
Comparison of the roles of mitogen-activated protein kinase kinase and phosphatidylinositol 3-kinase signal transduction in neutrophil effector function.
Topics: Androstadienes; Blotting, Western; Calcium-Calmodulin-Dependent Protein Kinases; Chemotactic Factors; Chemotaxis, Leukocyte; Chromones; Cytokines; Flavonoids; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Morpholines; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oncogene Protein p21(ras); Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Platelet Activating Factor; Protein Kinase Inhibitors; Protein Kinases; Respiratory Burst; Signal Transduction; Wortmannin; Zymosan | 1998 |
Role of phosphatidylinositol 3-kinase in human platelet aggregation.
Topics: Androstadienes; Arachidonic Acid; Collagen; Enzyme Inhibitors; Epinephrine; Humans; In Vitro Techniques; Kinetics; Phosphatidylinositol 3-Kinases; Platelet Activating Factor; Platelet Aggregation; Serotonin; Wortmannin | 1997 |
Inhibition by platelet-activating factor of Src- and hepatocyte growth factor-dependent invasiveness of intestinal and kidney epithelial cells. Phosphatidylinositol 3'-kinase is a critical mediator of tumor invasion.
Topics: Androstadienes; Animals; Azepines; Cell Adhesion Molecules; Cell Movement; Chromones; Colonic Neoplasms; Dogs; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Gene Expression Regulation, Neoplastic; Genes, src; GTP-Binding Proteins; Hepatocyte Growth Factor; Humans; Intestinal Mucosa; Kidney; Morpholines; Pertussis Toxin; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Platelet Activating Factor; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Protein-Tyrosine Kinases; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Signal Transduction; Thiazoles; Transformation, Genetic; Triazoles; Tumor Cells, Cultured; Virulence Factors, Bordetella; Wortmannin | 1998 |
A role for phosphatidylinositol 3-kinase in platelet aggregation in response to low, but not high, concentrations of PAF or thrombin.
Topics: Androstadienes; Animals; Blood Platelets; Chromones; Dose-Response Relationship, Drug; Enzyme Activation; Morpholines; Phosphatidylinositol 3-Kinases; Phosphatidylinositol Phosphates; Phosphoinositide-3 Kinase Inhibitors; Platelet Activating Factor; Platelet Aggregation; Rabbits; Thrombin; Wortmannin | 1999 |
Mitogen-activated protein kinase activation and regulation of cyclooxygenase 2 expression by platelet-activating factor and hCG in human endometrial adenocarcinoma cell line HEC-1B.
Topics: Adenocarcinoma; Androstadienes; Antineoplastic Agents, Hormonal; Chorionic Gonadotropin; Cyclic AMP; Cyclooxygenase 2; Endometrial Neoplasms; Enzyme Activation; Enzyme Inhibitors; Estradiol; Female; Flavonoids; Humans; Isoenzymes; Isoquinolines; Medroxyprogesterone Acetate; Membrane Proteins; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Mitogens; Platelet Activating Factor; Prostaglandin-Endoperoxide Synthases; Protein Kinase Inhibitors; Signal Transduction; Sulfonamides; Thionucleotides; Tumor Cells, Cultured; Wortmannin | 1999 |
A surrogate method for assessment of beta(2)-integrin-dependent adhesion of human eosinophils to ICAM-1.
Topics: Androstadienes; Butadienes; CD18 Antigens; Cell Adhesion; Dose-Response Relationship, Drug; Eosinophils; Genistein; Humans; Hypersensitivity, Immediate; Integrins; Intercellular Adhesion Molecule-1; Interleukin-5; N-Formylmethionine Leucyl-Phenylalanine; Nitriles; Phosphoinositide-3 Kinase Inhibitors; Platelet Activating Factor; Protein Kinase Inhibitors; Serum Albumin, Bovine; Wortmannin | 2000 |
Immediate and delayed VEGF-mediated NO synthesis in endothelial cells: role of PI3K, PKC and PLC pathways.
Topics: 1-Methyl-3-isobutylxanthine; Androstadienes; Animals; Calcimycin; Calcium; Cattle; Cells, Cultured; Chelating Agents; Chromones; Cyclic GMP; Diterpenes; Dose-Response Relationship, Drug; Egtazic Acid; Endothelial Growth Factors; Endothelium, Vascular; Enzyme Inhibitors; Ginkgolides; Indoles; Intercellular Signaling Peptides and Proteins; Ionophores; Lactones; Lymphokines; Maleimides; Morpholines; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nitroprusside; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Platelet Activating Factor; Platelet Membrane Glycoproteins; Protein Kinase C; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Serine; Signal Transduction; Time Factors; Type C Phospholipases; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors; Wortmannin | 2002 |
Platelet-activating factor mediates Helicobacter pylori lipopolysaccharide interference with gastric mucin synthesis.
Topics: Amidines; Androstadienes; Animals; Benzylamines; Enzyme Inhibitors; Gastric Mucins; Gastric Mucosa; Gastritis; Ginkgolides; Helicobacter Infections; Helicobacter pylori; In Vitro Techniques; Lactones; Lipopolysaccharides; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Phosphoinositide-3 Kinase Inhibitors; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Wortmannin | 2004 |
Trophic signals acting via phosphatidylinositol-3 kinase are required for normal pre-implantation mouse embryo development.
Topics: Androstadienes; Animals; Blastocyst; Calcium Signaling; Chromones; Culture Media; Culture Techniques; Dose-Response Relationship, Drug; Embryonic Development; Enzyme Inhibitors; Female; Mice; Mice, Knockout; Morpholines; Morula; Phosphatidylinositol 3-Kinases; Platelet Activating Factor; Platelet Membrane Glycoproteins; Pregnancy; Receptors, G-Protein-Coupled; RNA, Messenger; Wortmannin; Zygote | 2004 |
Platelet-activating factor mediates Porphyromonas gingivalis lipopolysaccharide interference with salivary mucin synthesis via phosphatidylinositol 3-kinase-dependent constitutive nitric-oxide synthase activation.
Topics: Amidines; Androstadienes; Animals; Apoptosis; Benzylamines; Cell Survival; Cells, Cultured; Disease Models, Animal; Dose-Response Relationship, Drug; Ginkgolides; Glucosamine; Lactones; Lipopolysaccharides; Mucins; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Platelet Activating Factor; Porphyromonas gingivalis; Rats; Rats, Sprague-Dawley; Saliva; Salivary Glands; Sublingual Gland; Tritium; Tumor Necrosis Factor-alpha; Up-Regulation; Wortmannin | 2004 |
Activation of extracellular signal-regulated kinase couples platelet-activating factor-induced adhesion and delayed apoptosis of human neutrophils.
Topics: Androstadienes; Apoptosis; bcl-Associated Death Protein; Carrier Proteins; Caspase 3; Caspases; CD11b Antigen; CD18 Antigens; Cell Adhesion; Cell Survival; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Flow Cytometry; Granulocytes; Humans; Inflammation; Neutrophils; Phosphatidylinositol 3-Kinases; Phosphorylation; Platelet Activating Factor; Signal Transduction; Time Factors; Up-Regulation; Wortmannin | 2004 |
Controlled pseudopod extension of human neutrophils stimulated with different chemoattractants.
Topics: Actins; ADP Ribose Transferases; Amides; Anaphylatoxins; Androstadienes; Botulinum Toxins; Chemotactic Factors; Chemotaxis; Humans; Interleukin-8; Intracellular Signaling Peptides and Proteins; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Platelet Activating Factor; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Pseudopodia; Pyridines; rho-Associated Kinases; rhoA GTP-Binding Protein; Wortmannin | 2004 |
Different pathways leading to activation of extracellular signal-regulated kinase and p38 MAP kinase by formyl-methionyl-leucyl-phenylalanine or platelet activating factor in human neutrophils.
Topics: Androstadienes; Aristolochic Acids; Calcium; Calcium Channel Blockers; Calcium Channels; Chromones; Dose-Response Relationship, Drug; Enzyme Inhibitors; Estrenes; Extracellular Signal-Regulated MAP Kinases; Humans; Imidazoles; Indoles; Maleimides; Models, Biological; Morpholines; N-Formylmethionine Leucyl-Phenylalanine; Naphthalenes; Neutrophils; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Phosphodiesterase Inhibitors; Phospholipases A; Phospholipases A2; Phosphorylation; Platelet Activating Factor; Protein Isoforms; Protein Kinase C; Pyrrolidinones; Type C Phospholipases; Wortmannin | 2005 |
Differential dependence of eosinophil chemotactic responses on phosphoinositide 3-kinase (PI3K).
Topics: Androstadienes; Cells, Cultured; Chemokine CCL11; Chemokines, CC; Chemotactic Factors, Eosinophil; Chemotaxis, Leukocyte; Chromones; Eosinophils; Humans; Morpholines; Phosphatidylinositol 3-Kinases; Platelet Activating Factor; Protein Kinase Inhibitors; Signal Transduction; Wortmannin | 2005 |
Cytosolic phospholipase A2 activation in Helicobacter pylori lipopolysaccharide-induced interference with gastric mucin synthesis.
Topics: Androstadienes; Animals; Arachidonic Acids; Endothelin-1; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Gastric Mucosa; Ginkgolides; Lactones; Lipopolysaccharides; Models, Biological; Mucins; Organophosphonates; Phosphatidylcholines; Phosphoinositide-3 Kinase Inhibitors; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Wortmannin | 2006 |
Interference by leptin with Helicobacter pylori lipopolysaccharide-induced cytosolic phospholipase A2 activation in gastric mucosal cells.
Topics: Androstadienes; Animals; Apoptosis; Arachidonic Acid; Arachidonic Acids; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Gastric Mucins; Gastric Mucosa; Ginkgolides; Lactones; Leptin; Lipopolysaccharides; Organophosphonates; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Platelet Membrane Glycoproteins; Protein Kinase Inhibitors; Rats; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled; Signal Transduction; Wortmannin | 2007 |
TNFalpha is a potent inducer of platelet-activating factor synthesis in adipocytes but not in preadipocytes. Differential regulation by PI3K.
Topics: Adipocytes; Androstadienes; Animals; Cell Differentiation; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Phosphatidylinositol 3-Kinases; Platelet Activating Factor; Rats; Rats, Wistar; Tumor Necrosis Factor-alpha; Wortmannin | 2008 |
PTEN/MAPK pathways play a key role in platelet-activating factor-induced experimental pulmonary tumor metastasis.
Topics: Androstadienes; Animals; Anthracenes; Butadienes; Cell Line; Humans; Imidazoles; Lung Neoplasms; MAP Kinase Signaling System; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Mitogen-Activated Protein Kinases; Nitriles; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Platelet Activating Factor; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Pyridines; Wortmannin | 2012 |