1-hexadecyl-2-acetyl-glycero-3-phosphocholine has been researched along with thromboxane b2 in 254 studies
| Studies (1-hexadecyl-2-acetyl-glycero-3-phosphocholine) | Trials (1-hexadecyl-2-acetyl-glycero-3-phosphocholine) | Recent Studies (post-2010) (1-hexadecyl-2-acetyl-glycero-3-phosphocholine) | Studies (thromboxane b2) | Trials (thromboxane b2) | Recent Studies (post-2010) (thromboxane b2) |
|---|---|---|---|---|---|
| 9,156 | 187 | 552 | 7,483 | 715 | 485 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 108 (42.52) | 18.7374 |
| 1990's | 128 (50.39) | 18.2507 |
| 2000's | 13 (5.12) | 29.6817 |
| 2010's | 5 (1.97) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Giessler, C; Mentz, G; Mentz, P; Mest, HJ | 1 |
| Desquand, S; Dumarey, C; Lefort, J; Vargaftig, BB | 2 |
| Ankri, A; Drobinski, G; Grosgogeat, Y; Maclouf, J; Mencia-Huerta, JM; Montalescot, G; Thomas, D | 1 |
| Aepfelbacher, M; Lux, I; Weber, PC; Ziegler-Heitbrock, HW | 1 |
| Esser, KM; Feuerstein, G; Hillegas, LM; Rabinovici, R; Renz, JF; Sofronski, MD; Vernick, J | 1 |
| Karvonen, JI; Koskinen, MO; Metsä-Ketelä, TJ; Moilanen, EK; Nieminen, MM; Tuomisto, L; Vapaatalo, H | 1 |
| Huang, TF; Ko, FN; Liou, MJ; Teng, CM; Wu, TS | 1 |
| Imaizumi, A; Kadiri, C; Leduc, D; Lefort, J; Vargaftig, BB | 1 |
| Smith, EA; Smith, IL | 1 |
| Zhang, JN | 1 |
| Leduc, D; Lefort, J; Pretolani, M; Vargaftig, BB | 1 |
| Lefort, J; Perrisoud, D; Pretolani, M; Vargaftig, BB; Venco, C | 1 |
| Feuerstein, G; Lynch, KM; Ohlstein, EH; Poyser, R; Rabinovici, R; Sellers, TS; Slivjak, MJ; Smith, EF; Sulpizio, A; Yue, TL | 1 |
| Kunievsky, B; Yavin, E | 1 |
| Doron, D; Feuerstein, G; Hallenbeck, JM; Heldman, E; Liu, Y; Lysko, PG; Sirén, AL; Yue, TL | 1 |
| Henderson, WR; Hodson, WA; Jackson, JC; Juul, SE; Murphy, JH; Standaert, TA; Truog, WE | 1 |
| Ben-Efraim, S; Bonta, IL; Mozes, T | 1 |
| Huang, SC; Huang, TF; Li, HL; Teng, CM; Wu, TS | 1 |
| Ikeuchi, H; Mason, AD; Pruitt, BA; Sakano, T; Sanchez, J | 1 |
| Burke, V; Douglas, AJ; McCulloch, RK; Mori, TA; Vandongen, R | 1 |
| Bisogno, G; Galbusera, M; Livio, M; Macconi, D; Orisio, S; Remuzzi, G; Viganò, G | 1 |
| Bergmann, R; Brecht, HM; Gokel, M; Hammer, C; Saumweber, DM; Zellner, C | 1 |
| Murphy, CT; Westwick, J | 1 |
| Flohé, S; Heinrich, PC; Hörstmann-Jungemann, K; Kirkpatrick, CJ; Klosterhalfen, B; Offner, F; Vogel, P | 1 |
| Bugelski, PJ; Esser, KM; Feuerstein, G; Griswold, DE; Hallenbeck, JM; Hillegass, LM; Lysko, PG; Rabinovici, R; Yue, TL | 1 |
| Drummer, C; Gerzer, R; Heim, JM; Karrenbrock, B; Valta-Seufzer, U | 1 |
| Alonso, J; Bustos, C; Egido, J; Goméz-Chiarri, M; Gómez-Guerrero, C; González, E; Lerma, JL; Ortiz, A; Robles, A | 1 |
| Elmore, M; Kellie, S; Murphy, CT; Westwick, J | 2 |
| Berti, F; Braquet, P; Rossoni, G | 1 |
| Braquet, P; Filep, JG; Mózes, T | 1 |
| Honda, ZI; Ichikawa, Y; Ishii, A; Mike, I; Seyama, Y; Shimizu, T | 1 |
| Peskar, BA; Pritze, S; Simmet, T | 1 |
| Calvo, IF; da Rocha, FA; de Falco, V; Fernandes, AJ; Jancar, S; Sirois, P | 1 |
| Becker, K; Förster, W; Lueddeckens, G; Rappold, R | 1 |
| Blasevich, M; Galli, C; Petroni, A; Visioli, F | 1 |
| Cooper, TM; Ingram, DM | 1 |
| Fenton, J; Gudewicz, PW; Kaplan, JE; Moon, DG; van der Zee, H | 1 |
| Bishai, I; Coceani, F; Hynes, N; Lees, J | 1 |
| Bergmann, R; Brecht, HM; Gokel, M; Hammer, C; Saumweber, DM | 1 |
| Ahmed, Y; Elder, MG; Sullivan, MH | 1 |
| Altavilla, D; Arena, A; Campo, GM; Caputi, AP; Santoro, G; Squadrito, F; Sturniolo, R | 1 |
| Lefort, J; Lellouch-Tubiana, A; Terlain, B; Vannier, E; Vargaftig, BB | 1 |
| Hofmann, B; Kertscher, HP; Ostermann, G; Till, U | 1 |
| Neugarten, J; Schlondorff, D; Yoo, J | 1 |
| Edwards, RJ; MacDermot, J; Storch, J | 1 |
| Geissler, FT; Henderson, WR; Kuzan, FB | 1 |
| Cerletti, C; Chen, ZM; De Gaetano, G; Del Maschio, A; Evangelista, V; Rajtar, G | 1 |
| Barnes, PJ; Giembycz, MA; Kroegel, C | 1 |
| Bachelet, M; Dumarey, C; Lefort, J; Malanchere, E; Pretolani, M; Silva, P; Vargaftig, BB | 1 |
| Croft, KD; Ysrael, MC | 1 |
| Tai, HH; Tanizawa, H | 2 |
| Chen, CC; Huang, TF; Huang, YL; Teng, CM; Yu, SM | 1 |
| Hamano, S; Ikeda, S; Kikuchi, S; Kojima, M; Komatsu, H; Kusama, H; Okegawa, T; Takehana, Y | 1 |
| Chao, W; Hanahan, DJ; Liu, HL; Olson, MS; Zhou, WG | 1 |
| Beilin, LJ; Croft, KD; Masarei, J; Rouse, I; Vandongen, R | 1 |
| DiSimone, AG; Earnest, MA; Fletcher, JR | 1 |
| Breslow, R; Cheng, JB; Conklyn, MJ; Pillar, JS; Shirley, JT; Showell, HJ | 1 |
| Kondo, K; Takayasu-Okishio, M; Terashita, Z | 1 |
| Ashmore, RC; Dauber, IM; Horwitz, LD; McMurtry, IF; O'Brien, RF; Stelzner, TJ; VanBenthuysen, KM | 1 |
| Farhat, M; Feuerstein, G; Perera, PY; Rabinovici, R; Vogel, SN; Yue, TL | 1 |
| Feuerstein, G; Rabinovici, R; Rudolph, AS; Yue, TL | 1 |
| Braquet, P; Cirino, M; Desquand, S; Lagente, V; Lefort, J; Randon, J; Touvay, C; Vargaftig, BB; Vilain, B | 1 |
| Lefer, AM | 1 |
| Lapointe, DS; Olson, MS | 1 |
| Bompiani, GD; Cardella, F; Davì, G; Giardina, E; Meli, F; Strano, A; Triolo, G | 1 |
| Faustman, EM; Geissler, FT; Henderson, WR; Kuzan, FB | 1 |
| Bryant, NL; Guccione, MA; Kinlough-Rathbone, RL; Mustard, JF; Packham, MA | 1 |
| Emery, D; Margolskee, D; Nadel, JA; Ueki, IF; Widdicombe, JH; Yergey, J | 1 |
| Bielawiec, M; Bodzenta-Lukaszyk, A; Gabryelewicz, A; Lukaszyk, A | 1 |
| Braquet, P; Jancar, S; Sirois, P | 3 |
| Moore, JN; Morris, DD | 1 |
| Fisher, RA; Hanahan, DJ; Olson, MS; Revtyak, GE; Steinhelper, ME | 1 |
| Fondacaro, JD; Griswold, DE; Rachmilewitz, D; Schwartz, LW; Simon, PL; Wasserman, MA | 1 |
| Fitzgerald, MF; Parente, L; Whittle, BJ | 1 |
| Bachelet, M; Béréziat, G; Kadiri, C; Masliah, J; Vargaftig, BB | 1 |
| Fradin, A; Henson, PM; Maclouf, J; Murphy, RC; Vausbinder, L; Zirrolli, JA | 1 |
| Bondy, GS; Gentry, PA | 1 |
| Gentry, PA; Liptrap, RM; Niemuller, C; Ross, ML | 1 |
| Kendrew, PJ; Nidorf, SM; Strophair, J; Sturm, M; Taylor, RR | 1 |
| Jakowec, DM; Neiman, J; Packham, MA; Rand, ML | 1 |
| Dembinska-Kiec, A; Muller, MK; Peskar, BA; Peskar, BM | 1 |
| McCulloch, RK; Rouse, IL; Summers, J; Vandongen, R | 1 |
| Becker, K; Braquet, P; Förster, W; Lueddeckens, G | 1 |
| Beilin, LJ; Kendrew, PJ; Strophair, JM; Sturm, MJ; Taylor, RR; Vandongen, R | 1 |
| Fitzgerald, MF; Moncada, S; Parente, L | 1 |
| Blair, IA; Cragoe, EJ; Frazer, M; Limbird, LE; Reed, PW; Schwartzberg, MS; Sweatt, JD | 1 |
| Beilin, LJ; Codde, JP; Hill, KJ; Mori, TA; Vandongen, R | 1 |
| Borgeat, P; Braquet, P; Harczy, M; Maclouf, J; Pradelles, P; Sirois, P | 2 |
| Lefer, AM; Stahl, GL | 1 |
| Anfossi, G; Cavalot, F; Emanuelli, G; Massucco, P; Mularoni, E; Trovati, M | 1 |
| Felsen, D; Freund, RM; Vaughan, ED; Weisman, SM | 1 |
| Benveniste, J; Coëffier, E; Desquand, S; Floch, A; Lefort, J; Maridonneau-Parini, I; Randon, J; Sedivy, P; Vargaftig, BB | 1 |
| Caravella, SJ; Clark, DA; McNeill, H; Miller, MJ; Mullane, KM | 1 |
| Barden, A; Beilin, LJ; Codde, JP; Croft, KD; Vandongen, R | 1 |
| Bradley, LM; Czaja, JF; Feuerstein, G; Goldstein, RE | 1 |
| Frölich, JC; Küster, LJ | 2 |
| Ambler, J; Birch, J; Maguire, ED; Wallis, RB | 1 |
| Dejana, E; Prosdocimi, M; Zanetti, A; Zatta, A | 1 |
| Dahl, ML | 1 |
| Apprill, P; Ashton, J; Buja, LM; Campbell, WB; Raheja, S; Schmitz, JM; Tilton, G; Willerson, JT | 1 |
| Darius, H; Lefer, AM; Smith, JB | 1 |
| Altman, R; Cacchione, R; Rouvier, J; Scazziota, A | 1 |
| Braquet, P; Desquand, S; Etienne, A; Lagente, V; Lefort, J; Maridonneau-Parini, I; Randon, J; Touvay, C; Vargaftig, BB; Vilain, B | 1 |
| Filep, J; Földes-Filep, E | 1 |
| Grigorian, GY; Ryan, US | 1 |
| Becker, K; Braquet, P; Förster, W | 1 |
| Adkinson, NF; Davidson, DA; Lichtenstein, LM; Schleimer, RP | 1 |
| Altman, R; Scazziota, A | 1 |
| Akkerman, JW; Gorter, G; Hasselaar, P; Kloprogge, E | 1 |
| Berti, F; Braquet, P; Omini, C; Rossoni, G | 1 |
| Chen, WY; Ko, WC; Ouyang, CH; Teng, CM | 1 |
| Csonka-Khalifah, L; Maguire, MH | 1 |
| Maclouf, J; Pradelles, P; Robidoux, C; Sirois, P | 1 |
| Altman, R; Funes, JC; Scazziota, A | 1 |
| Cloutier, S; Jancar, S; Provençal, B; Sirois, P; Thériault, P | 1 |
| Ezra, D; Feuerstein, G; Goldstein, RE; Hayes, E; Ramwell, PW | 1 |
| Adachi, M; Imai, T; Kamiya, I; Kobayashi, H; Nishikata, H; Okada, Y; Okazawa, A; Satoh, H; Takahashi, T | 1 |
| Lefort, J; Pretolani, M; Vargaftig, BB | 2 |
| Berti, F; Magni, F; Rossoni, G | 1 |
| Becker, K; Förster, W | 1 |
| Beilin, LJ; Codde, J; Croft, KD; Vandongen, R | 1 |
| Adachi, M; Imai, T; Kamiya, I; Kobayashi, H; Nishikata, H; Okazawa, A; Satoh, H; Takahashi, T; Yamaguchi, H | 1 |
| López-Farré, A; López-Novoa, JM; Torralbo, M | 1 |
| Kobayashi, T; Koyama, S; Kusama, S; Toyofuku, T | 1 |
| Beilin, LJ; Strophair, J; Sturm, M; Taylor, RR; Vandongen, R | 1 |
| Aliaga, M; Barbara, M; Bruniquel, F; Couzinier, JP; Delhon, A; Puech, L; Tarayre, JP; Tisne-Versailles, J | 1 |
| Arroyave, JL; Gonzalez-Crussi, F; Hsueh, W | 1 |
| Benveniste, J; Brink, C; Brunelleschi, S; Haye-Legrand, I; Labat, C; Norel, X | 1 |
| Adkinson, NF; Lichtenstein, LM; MacGlashan, DW; Peters, SP; Pinckard, RN; Schleimer, RP | 1 |
| Braquet, P; Pignol, B; Pouliot, C; Rola-Pleszczynski, M | 1 |
| Birch, J; Martin, JF; Milner, PC; Szczeklik, A; Watkins, J | 1 |
| Bayer, T; Dorsch, W; Ettl, M; Hein, G; Scheftner, P; Wagner, H; Weber, J | 1 |
| Kanaji, K; Okuma, M; Sensaki, S; Sugiyama, T; Uchino, H; Ushikubi, F | 1 |
| Angle, MJ; McManus, LM; Pinckard, RN; Showell, HJ | 1 |
| Lefort, J; Malanchère, E; Pretolani, M; Vargaftig, BB | 1 |
| Beilin, LJ; Codde, JP; Croft, KD; Sturm, MJ; Vandongen, R | 1 |
| Robertson, DN; Smith, GM | 1 |
| Handley, DA; Saunders, RN; Van Valen, RG | 1 |
| Bruniquel, F; Couzinier, JP; Delhon, A; Puech, L; Tarayre, JP; Tisne-Versailles, J | 1 |
| Filep, J; Frölich, JC; Küster, LJ | 1 |
| Honey, AC; Lad, N; Tuffin, DP | 1 |
| Burhop, KE; Garcia, JG; Kaplan, JE; Lo, SK; Malik, AB; Selig, WM; van der Zee, H | 1 |
| de Gaetano, G; Dejana, E; Finesso, M; Gorio, A; Languino, LR; Prosdocimi, M; Tessari, F | 1 |
| Felsen, D; Vaughan, ED; Weisman, SM | 1 |
| FitzGerald, GA; Pedersen, AK | 1 |
| Cerletti, C; de Gaetano, G; Lauri, D | 1 |
| Canciani, MT; Cattaneo, M; Mannucci, PM | 1 |
| Brehm, G; Hiller, E; Korth, R; Riess, H | 1 |
| Arnold, JH; Cataland, S; Greco, NJ; O'Dorisio, TM; Panganamala, RV | 1 |
| Kakkar, VV; Krishnamurthi, S; Westwick, J | 1 |
| MacIntyre, DE; Marks, G; Pollock, WK; Shaw, AM; Westwick, J | 1 |
| Ayer, DE; Gorman, RR; Miller, OV | 1 |
| Hartung, HP | 1 |
| Lefer, AM; Müller, HF; Smith, JB | 1 |
| Block, HU; Ostermann, G; Till, U | 1 |
| Hamasaki, Y; Mojarad, M; Saga, T; Said, SI; Tai, HH | 1 |
| O'Flaherty, JT; Stimler, NP | 1 |
| Apffel, D; Benveniste, J; Bessin, P; Bonnet, J; Desgroux, L; Pelas, I; Soulard, C | 1 |
| Rao, GH; White, JG | 1 |
| Fitzpatrick, FA; Hanahan, DJ; McManus, LM; Pinckard, RN | 1 |
| Blank, ML; Feuerstein, G; Kopin, IJ; Krausz, MM; Snyder, F; Zukowska-Grojec, Z | 1 |
| Benveniste, J; Fouque, F; Odiot, J; Vargaftig, BB | 1 |
| Hanahan, DJ; Klusick, SJ; Shaw, JO | 1 |
| Crawford, MH; Fitzpatrick, FA; Hanahan, DJ; McManus, LM; O'Rourke, RA; Pinckard, RN | 1 |
| Antunes, E; Cirino, G; de Nucci, G; Donato, JL; Faro, R; Hyslop, S; Landucci, EC; Marangoni, S; Oliveira, B | 1 |
| Duncker, HP; Heller, A; Koch, T; Neuhof, H; Schaible, R; van Ackern, K | 1 |
| Giessler, C; Heinroth-Hoffmann, I; Meissner, N; Mest, HJ; Pönicke, K | 1 |
| Braquet, P; Butterly, DW; Coffman, TM; Pirotzky, E; Ruiz, P; Spurney, RF | 1 |
| Brocchieri, A; Grignani, G; Moroni, M; Porta, C; Saporiti, A | 1 |
| Arribas, I; Díez-Marques, ML; García-Escribano, MC; Pérez de Lema, G; Rodríguez-Puyol, D; Rodríguez-Puyol, M | 1 |
| Keuskamp, ZJ; Madretsma, GS; Van Dijk, JP; Zijlstra, FJ | 1 |
| Desquand, S; Hatmi, M; Lefort, J; Pina, M; Priego, JG; Ruffié, C; Vargaftig, BB | 1 |
| Chandel, B; Deshpande, Y; Kaminski, DL; Kulkarni, A; Longo, WE; Niehoff, M; Polities, G; Vernava, AM | 1 |
| Chern, JW; Chou, TC; Ding, YA; Yen, MH | 1 |
| Chen, A; Chen, WP; Lin, CY | 1 |
| Arribas-Gómez, I; Díez-Marqués, ML; Duque-Marín, I; Lucio-Cazaña, J; Pérez de Lema, G; Rodríguez-Puyol, D; Rodríguez-Puyol, M | 1 |
| Okano, S; Tagawa, M; Urakawa, N | 1 |
| Coffman, TM; Goulet, JL; Koller, BH; Latour, AM; Snouwaert, JN | 1 |
| Chandel, B; Deshpande, Y; Kaminski, DL; Li, AP; Longo, WE; Stratton, MD; Vernava, AM | 1 |
| Imai, T; Imai, Y; Kawano, T; Miyasaka, K; Okuyama, K; Takata, M | 1 |
| Adachi, M; Horikoshi, S; Idaira, K; Imai, T; Kurokawa, M; Mita, S; Okamoto, M | 1 |
| Barnes, PJ; Carty, TJ; Chung, KF; Eskra, JD; O'Connor, BJ; Uden, S | 1 |
| Blasevich, M; Colombo, C; Galella, G; Galli, C; Papini, N; Petroni, A; Salami, M | 1 |
| Alemany, M; Bastida, E; Bozzo, J; Hernández, R; Ordinas, A | 1 |
| Chang, SW; Chen, CR; Voelkel, NF | 1 |
| Chen, IS; Hsiao, G; Ko, FN; Teng, CM; Wu, SJ | 1 |
| Fukuoka, T; Nakajima, Y; Nakano, H | 1 |
| Anglin, C; Carson, R; Clapp, N; Fretland, D; Hansard, R; Henke, M; Walsh, R; Widomski, D | 1 |
| Levine, BA; Olson, MS; Zhou, W | 1 |
| Cissik, JH; Dalton, LM; McGlasson, DL; Patterson, WR | 1 |
| Chang, YL; Chen, IS; Huang, TF; Ishii, H; Ko, FN; Teng, CM; Yu, SM | 1 |
| Goff, AK; Slama, H; Vaillancourt, D | 1 |
| Carrick, JB; Moore, JN; Morris, DD | 1 |
| Beilin, LJ; Croft, KD | 1 |
| Fu, J; Li, PS; Yu, HP | 1 |
| Johnson, LW; Kruse-Elliott, KT; Olson, NC | 1 |
| Dodam, JR; Kruse-Elliott, KT; Olson, NC; Whorton, AR | 1 |
| Amore, A; Bocchietto, E; Bussolino, F; Cavallo, F; Coppo, R; Gianoglio, B; Peruzzi, L; Porcellini, MG | 1 |
| Kroegel, C; Matthys, H | 1 |
| Miura, K; Yamamoto, K; Yamanaka, S; Yukimura, T | 1 |
| Bugelski, PJ; Esser, KM; Feuerstein, G; Hillegass, LM; Rabinovici, R; Vernick, J | 1 |
| Bartula, L; Kadesky, K; Kalley-Taylor, B; Myers, SI; Riva, A; Turnage, R | 1 |
| Butler, SM; Craddock, SD; Meyer, JJ; Pettigrew, LC; Tai, HH; Yokel, RA | 1 |
| Han, Q; Miller, JE; Olson, MS; Shen, F; Zhou, W | 1 |
| Ikemura, T; Ishii, H; Kase, H; Kitamura, S; Manabe, H; Miki, I; Ohmori, K; Onuma, K; Sasaki, Y; Sato, S | 1 |
| Lee, CS; Shaio, MF; Yang, KD | 1 |
| Albert, DH; Carter, GW; Grossman, JE; Kruse-Elliott, KT; Summers, JB; Zimmerman, JJ | 1 |
| Xiao, J; Zao, D; Zhen, H | 1 |
| Goto, Y; Ishimaru, S; Izaki, S; Kitamura, K; Matsuzaki, M; Yamamoto, T; Yudate, F | 1 |
| Kohno, S; Nabe, T; Yamamura, H | 1 |
| Brasch, F; Featherstone, RL; Klein, T; Müller, KM; Nüsing, R; Uhlig, S; Ullrich, V; von Bethmann, A; Wendel, A | 1 |
| Aïssa, J; Arnoux, B; Benveniste, J; Nathan, N | 1 |
| Ando, H; Kobayashi, K; Nakatani, T; Sakamoto, Y | 1 |
| Hauptmann, S; Kirkpatrick, CJ; Klosterhalfen, B; Küpper, W; Offner, FA; Tietze, L; Töns, C | 1 |
| Beilin, LJ; Burke, V; Mori, TA; Morris, J; Ritchie, J | 1 |
| Andrade, LE; Jancar, S; Rocha, FA; Russo, M | 1 |
| Arnold, F; Cherry, GW; He, CF | 1 |
| Chang, YL; Hsueh, CM; Ko, FN; Lee, SS; Liu, KC; Teng, CM | 1 |
| Bellamy, MC; Galley, HF; Webster, NR | 1 |
| Dent, G; Leff, AR; Magnussen, H; Muñoz, NM; Rabe, KF; Rühlmann, E; Zhu, X | 1 |
| Kruse-Elliott, KT; Olson, NC; Whorton, AR | 1 |
| Bratton, DL; Fadok, VA; Freed, PW; Henson, PM; Konowal, A; Westcott, JY | 1 |
| Alper, CM; Burckart, GJ; Diven, WF; Doyle, WJ; Evans, RW; Jaffe, R | 1 |
| Hsiao, G; Jong, TT; Ko, FN; Teng, CM | 1 |
| Ding, JS; He, JL; Li, HP; Quan, CJ | 1 |
| Coghe, J; Deby-Dupont, G; Lekeux, P; Uystepruyst, C; Van de Weerdt, ML | 1 |
| Guo, ZG; Zeng, S | 1 |
| Denizot, Y; Feiss, P; Nathan, N | 1 |
| Andrews, MJ; Bailey, SR; Cunningham, F; Elliott, J | 1 |
| Ko, FN; Liao, CH; Teng, CM; Wu, CL | 1 |
| Andrews, MJ; Bailey, SR; Cunningham, FM; Elliott, J | 1 |
| Grignani, G; Maiolo, A; Porta, C; Tua, A | 1 |
| Fujimura, A; Kawaguchi, A; Sugimoto, K | 1 |
| Gresele, P; Mezzasoma, AM; Venditti, G; Vezza, R | 1 |
| Murakami, M; Murota, M; Oketani, K; Sakai, H; Suzuki, T; Takeguchi, N; Uchiumi, T | 1 |
| Abran, D; Bernier, SG; Brault, S; Checchin, D; Chemtob, S; Gobeil, F; Hou, X; Joyal, JS; Marrache, AM; Peri, K; Quiniou, C; Sennlaub, F; Varma, DR | 1 |
| Beck-Speier, I; Dayal, N; Denzlinger, C; Haberl, C; Heyder, J; Maier, KL; Ziesenis, A | 1 |
| Bancalari, E; Huang, J; Rodriguez, MM; Smalling, WE; Suguihara, C | 1 |
| Michibayashi, T | 1 |
| Basilico, F; Bombardelli, E; De Palma, A; Mauri, P; Morazzoni, P; Pozzi, F; Riva, A; Rossoni, G | 1 |
| Cai, Y; Chen, L; Jiang, X; Tian, H; Wu, C; Xu, R; Ye, Q; Yuan, W; Zhang, X | 1 |
| Deev, AD; Dobrovol'skiĭ, AB; Katkova, OV; Laguta, PS; Panchenko, EP; Titaeva, EV | 1 |
| Jalil, J; Jantan, I; Jasamai, M; Saadawi, S | 1 |
| Kang, JW; Lee, JH; Min, BS | 1 |
| Chou, YI; Kong, J; Song, R; Yan, L; Zhang, Y; Zheng, L | 1 |
| Chuansumrit, A; Kadegasem, P; Sirachainan, N; Sirivadhanakul, P; Songdej, D; Wongwerawattanakoon, P | 1 |
2 review(s) available for 1-hexadecyl-2-acetyl-glycero-3-phosphocholine and thromboxane b2
| Article | Year |
|---|---|
Interactions of arachidonic acid metabolites and platelet activating factor and mechanism of action in hypersensitivity reactions.
Topics: Animals; Arachidonic Acids; Dinoprostone; Diterpenes; Eicosanoic Acids; Enzyme Activation; Ginkgolides; Guinea Pigs; Hypersensitivity; Inflammation; Lactones; Leukotriene B4; Lung; Muscle Contraction; Phospholipases; Phospholipases A; Platelet Activating Factor; Prostaglandins E; SRS-A; Thromboxane B2 | 1987 |
Role of thromboxane A2.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Collagen; Epinephrine; Humans; Indomethacin; Kinetics; Platelet Activating Factor; Platelet Aggregation; Prostaglandin Endoperoxides; Prostaglandin Endoperoxides, Synthetic; Receptors, Prostaglandin; Receptors, Thromboxane; Serotonin; Thrombin; Thromboxane A2; Thromboxane B2 | 1985 |
9 trial(s) available for 1-hexadecyl-2-acetyl-glycero-3-phosphocholine and thromboxane b2
| Article | Year |
|---|---|
Inhaled budesonide fails to inhibit the PAF-induced increase in plasma leukotriene B4 in man.
Topics: Administration, Inhalation; Adult; Blood Platelets; Bronchodilator Agents; Budesonide; Catecholamines; Drug Synergism; Female; Histamine; Humans; Leukotriene B4; Male; Methacholine Chloride; Middle Aged; Platelet Activating Factor; Platelet Count; Pregnenediones; Reference Values; Thromboxane B2 | 1992 |
Comparison of anti-platelet properties of molsidomine, isosorbide-5-mononitrate and placebo in healthy volunteers.
Topics: Adult; Bleeding Time; Cyclic GMP; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Isosorbide Dinitrate; Male; Molsidomine; Platelet Activating Factor; Platelet Aggregation Inhibitors; Random Allocation; Reference Values; Thromboxane B2 | 1991 |
Role of thromboxane A2 as a mediator of platelet-activating-factor-induced aggregation of human platelets.
Topics: Adult; Aspirin; Collagen; Humans; Male; Platelet Activating Factor; Platelet Aggregation; Serotonin; Thromboxane A2; Thromboxane B2 | 1989 |
Inhibitory effect of UK,74505, a potent and specific oral platelet activating factor (PAF) receptor antagonist, on airway and systemic responses to inhaled PAF in humans.
Topics: Administration, Inhalation; Administration, Oral; Airway Resistance; Bronchoconstriction; Dihydropyridines; Dose-Response Relationship, Drug; Double-Blind Method; Eicosanoids; Humans; Imidazoles; Leukocyte Count; Leukotriene E4; Male; Neutropenia; Neutrophils; Platelet Activating Factor; Thromboxane B2 | 1994 |
Interactions between dietary fat, fish, and fish oils and their effects on platelet function in men at risk of cardiovascular disease.
Topics: Adult; Animals; Blood Platelets; Cardiovascular Diseases; Collagen; Diet; Diet, Fat-Restricted; Dietary Fats; Dietary Fats, Unsaturated; Fatty Acids, Omega-3; Fish Oils; Fishes; Humans; Male; Middle Aged; Phospholipids; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Risk Factors; Thromboxane B2 | 1997 |
Ketoprofen and phenylbutazone attenuation of PAF-induced lung inflammation in calves.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cattle; Cattle Diseases; Dinoprostone; Ketoprofen; Leukotriene B4; Male; Phenylbutazone; Placebos; Platelet Activating Factor; Pneumonia; Respiration; Thromboxane B2 | 1999 |
LC-MS characterization of terpene lactones in plasma of experimental animals treated with Ginkgo biloba extracts Correlation with pharmacological activity.
Topics: Adult; Animals; Biological Availability; Bronchoconstriction; Chromatography, Liquid; Diterpenes; Ginkgo biloba; Ginkgolides; Guinea Pigs; Histamine; Humans; Lactones; Male; Mass Spectrometry; Models, Molecular; Molecular Conformation; Ovalbumin; Plant Extracts; Platelet Activating Factor; Terpenes; Thromboxane B2 | 2006 |
[Aspirin resistance in patients with stable ischemic heart disease].
Topics: Aged; Aspirin; Coronary Angiography; Drug Monitoring; Drug Resistance; Echocardiography, Transesophageal; Electrocardiography; Exercise Test; Female; Humans; Male; Middle Aged; Myocardial Ischemia; Platelet Activating Factor; Risk Factors; Severity of Illness Index; Thromboxane B2; Treatment Outcome | 2010 |
Increased endothelial activation in α-thalassemia disease.
Topics: Adolescent; Adult; alpha-Thalassemia; Biomarkers; Blood Transfusion; Child; Child, Preschool; Endothelium, Vascular; Female; Ferritins; Humans; Infant; Iron Chelating Agents; Male; Platelet Activating Factor; Platelet Activation; Thrombomodulin; Thromboxane B2; Vascular Cell Adhesion Molecule-1; von Willebrand Factor | 2019 |
243 other study(ies) available for 1-hexadecyl-2-acetyl-glycero-3-phosphocholine and thromboxane b2
| Article | Year |
|---|---|
Interactions of prostanoids with the platelet activating factors.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Azepines; Guinea Pigs; Heart; Iloprost; In Vitro Techniques; Indomethacin; Myocardial Contraction; Perfusion; Platelet Activating Factor; Prostaglandins; Sulfonamides; Thromboxane A2; Thromboxane B2; Triazoles | 1992 |
Interference of BN 52021, an antagonist of PAF, with different forms of active anaphylaxis in the guinea-pig: importance of the booster injection.
Topics: Anaphylaxis; Animals; Bronchoconstriction; Diterpenes; Female; Ginkgolides; Guinea Pigs; Histamine Release; Immunization, Secondary; In Vitro Techniques; Lactones; Lung; Male; Ovalbumin; Platelet Activating Factor; Thromboxane B2 | 1991 |
Lack of platelet-activating factor release during reversible myocardial ischaemia.
Topics: Angina Pectoris; Angioplasty, Balloon, Coronary; Humans; Myocardial Ischemia; Platelet Activating Factor; Thromboxane B2 | 1992 |
Bacterial lipopolysaccharide up-regulates platelet-activating factor-stimulated Ca2+ mobilization and eicosanoid release in human Mono Mac 6 cells.
Topics: Antigens, Surface; Arachidonic Acid; Calcium; Cells, Cultured; Eicosanoids; Humans; Lipopolysaccharides; Macrophages; Monocytes; Phagocytosis; Platelet Activating Factor; Signal Transduction; Superoxides; Thromboxane B2; Up-Regulation | 1992 |
Platelet activating factor mediates interleukin-2-induced lung injury in the rat.
Topics: Animals; Azepines; Blood Pressure; Interleukin-2; Leukocyte Count; Lung Diseases; Male; Peroxidase; Platelet Activating Factor; Platelet Count; Rats; Rats, Inbred Strains; Thromboxane B2; Triazoles; Tumor Necrosis Factor-alpha | 1992 |
PAF antagonism in vitro and in vivo by aglafoline from Aglaia elliptifolia Merr.
Topics: Adenosine Triphosphate; Animals; Benzofurans; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Humans; In Vitro Techniques; Male; Phosphatidylinositols; Plant Extracts; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Rabbits; Rats; Rats, Inbred Strains; Thromboxane B2 | 1992 |
Guinea-pig treatment with pertussis toxin suppresses macrophage-dependent bronchoconstriction by fMLP and fails to inhibit the effects of PAF.
Topics: Adenosine Diphosphate Ribose; Animals; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Cholera Toxin; Cyclic AMP; Electrophoresis, Polyacrylamide Gel; GTP-Binding Proteins; Guinea Pigs; Lung; Macrophages, Alveolar; N-Formylmethionine Leucyl-Phenylalanine; Pertussis Toxin; Platelet Activating Factor; Superoxides; Thromboxane B2; Trachea; Virulence Factors, Bordetella | 1992 |
Inhibition of PAF-induced activation of human platelets by verapamil.
Topics: Adenosine Triphosphate; Blood Platelets; Calcium; Calcium Channels; Humans; Platelet Activating Factor; Platelet Activation; Thromboxane B2; Verapamil | 1992 |
[Interference of platelet-activating factor antagonist, BN50739 with the releasing of inflammatory mediators from anaphylactic lung of guinea pig].
Topics: Alveolitis, Extrinsic Allergic; Animals; Azepines; Female; Guinea Pigs; Histamine; Lung; Male; Ovalbumin; Platelet Activating Factor; Prostaglandins F; SRS-A; Thromboxane B2; Triazoles | 1992 |
Effect of human recombinant interleukin-5 on in vitro responsiveness to PAF of lung from actively sensitized guinea-pigs.
Topics: Animals; Bronchi; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Guinea Pigs; Histamine Release; In Vitro Techniques; Interleukin-5; Lung; Male; Muscle Contraction; Perfusion; Platelet Activating Factor; Recombinant Proteins; Respiratory Hypersensitivity; Thromboxane B2 | 1992 |
Inhibition by azelastine of the effects of platelet-activating factor in lungs from actively sensitised guinea-pigs.
Topics: Animals; Arachidonic Acid; Bronchoconstriction; Guinea Pigs; Histamine; Immunization; Injections, Intra-Arterial; Leukotrienes; Lung; Male; Ovalbumin; Phthalazines; Platelet Activating Factor; Platelet Aggregation Inhibitors; Pulmonary Artery; Thromboxane B2 | 1992 |
Pharmacological profile of G619, a new platelet aggregation inhibitor.
Topics: Adenosine Diphosphate; Animals; Benzamides; Calcium; Collagen; Dogs; Epinephrine; Fibrinogen; Humans; Male; Phenylacetates; Picolines; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Prostaglandin Endoperoxides, Synthetic; Rabbits; Rats; Rats, Sprague-Dawley; Receptors, Thromboxane; Shock, Septic; Sulfonamides; Thrombin; Thromboxane B2; Vasoconstriction | 1992 |
Platelet-activating factor stimulates arachidonic acid release and enhances thromboxane B2 production in intact fetal rat brain ex vivo.
Topics: Animals; Arachidonic Acid; Brain Chemistry; Calcium; Fetus; Humans; Phospholipids; Platelet Activating Factor; Rats; Rats, Wistar; Telencephalon; Thromboxane B2 | 1992 |
Release of proinflammatory and prothrombotic mediators in the brain and peripheral circulation in spontaneously hypertensive and normotensive Wistar-Kyoto rats.
Topics: Animals; Brain; Cerebrovascular Disorders; Dose-Response Relationship, Drug; Hypertension; Injections, Intravenous; Injections, Intraventricular; Leukocyte Count; Lipopolysaccharides; Platelet Activating Factor; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Reference Values; Risk Factors; Thromboxane B2; Tumor Necrosis Factor-alpha | 1992 |
Acute changes in vasoactive lipid mediators in experimental hyaline membrane disease.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acids; Fetal Blood; High-Frequency Ventilation; Humans; Hyaline Membrane Disease; Infant, Newborn; Lung; Macaca nemestrina; Platelet Activating Factor; Respiration, Artificial; SRS-A; Thromboxane B2; Time Factors | 1992 |
Lethal and non-lethal course of endotoxic shock is determined by interactions between tumor necrosis factor, platelet activating factor and eicosanoids.
Topics: Animals; Blood Pressure; Diterpenes; Eicosanoids; Endotoxins; Escherichia coli; Ginkgolides; Indomethacin; Lactones; Platelet Activating Factor; Shock, Septic; Swine; Thromboxane B2; Tumor Necrosis Factor-alpha | 1992 |
Antiplatelet actions of some coumarin compounds isolated from plant sources.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Arachidonic Acid; Blood Platelets; Coumarins; Membrane Lipids; Molecular Structure; Phospholipids; Plants; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Prostaglandin Endoperoxides, Synthetic; Rabbits; Thrombin; Thromboxane B2 | 1992 |
The effects of platelet-activating factor (PAF) and a PAF antagonist (CV-3988) on smoke inhalation injury in an ovine model.
Topics: Animals; Dinoprostone; Lipid Peroxidation; Male; Malondialdehyde; Phospholipid Ethers; Platelet Activating Factor; Platelet Count; Sheep; Smoke Inhalation Injury; Thromboxane B2; Time Factors | 1992 |
Differential effect of aspirin on platelet aggregation in IDDM.
Topics: Adult; Aspirin; Blood Pressure; Cholesterol; Collagen; Diabetes Mellitus, Type 1; Fatty Acids, Omega-3; Humans; Linoleic Acid; Linoleic Acids; Male; Membrane Fluidity; Phospholipids; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Reference Values; Thromboxane B2 | 1992 |
Defective platelet aggregation in response to platelet-activating factor in uremia associated with low platelet thromboxane A2 generation.
Topics: Adult; Aged; Blood Platelets; Female; Humans; Male; Middle Aged; Platelet Activating Factor; Platelet Aggregation; Protein Binding; Radioimmunoassay; Thromboxane A2; Thromboxane B2; Uremia | 1992 |
Studies on xenograft rejection: the role of leukocytes and prostaglandins and their modulation by the hetrazepine WEB 2086BS.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Azepines; Erythrocyte Count; Graft Rejection; Hemagglutinins; Hemoperfusion; Humans; Kidney Transplantation; Leukocytes; Platelet Activating Factor; Swine; Thromboxane B2; Transplantation, Heterologous; Triazoles | 1992 |
Selective inhibition of protein kinase C. Effect on platelet-activating-factor-induced platelet functional responses.
Topics: Animals; Blood Platelets; Calcium; Enzyme Activation; Indoles; Kinetics; Maleimides; Phosphorylation; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Protein Kinase C; Rabbits; Serotonin; Signal Transduction; Tetradecanoylphorbol Acetate; Thromboxane B2 | 1992 |
Time course of various inflammatory mediators during recurrent endotoxemia.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Inflammation; Interleukin-6; Lipopolysaccharides; Platelet Activating Factor; Pulmonary Wedge Pressure; Shock, Septic; Swine; Thromboxane B2; Time Factors; Tumor Necrosis Factor-alpha | 1992 |
Priming by platelet-activating factor of endotoxin-induced lung injury and cardiovascular shock.
Topics: Animals; Body Water; Cardiovascular Diseases; Drug Synergism; Endotoxins; Escherichia coli; Hemodynamics; Lipopolysaccharides; Lung; Lung Diseases; Male; Microscopy, Electron, Scanning; Organ Size; Peroxidase; Platelet Activating Factor; Rats; Rats, Inbred Strains; Thromboxane B2; Tumor Necrosis Factor-alpha | 1991 |
Involvement of lipid mediators in the pathogenesis of experimental nephrosis in rats: its pharmacological modulation.
Topics: Animals; Dinoprostone; Doxorubicin; Kidney Glomerulus; Lipoxygenase Inhibitors; Male; Nephrosis, Lipoid; Platelet Activating Factor; Platelet Membrane Glycoproteins; Proteinuria; Random Allocation; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Thromboxane B2 | 1991 |
Comparison of the role of protein kinase C in platelet functional responses induced by three different mechanisms, PAF, ionomycin and arachidonic acid.
Topics: Alkaloids; Animals; Arachidonic Acid; Calcium; Feedback; Ionomycin; Phosphorylation; Platelet Activating Factor; Platelet Activation; Platelet Membrane Glycoproteins; Protein Kinase C; Rabbits; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Serotonin; Staurosporine; Tetradecanoylphorbol Acetate; Thromboxane B2 | 1991 |
Immune release of histamine and other lipid mediators from guinea-pig isolated kidney: antagonism by BN-52021.
Topics: Animals; Biological Assay; Diterpenes; Ginkgolides; Guinea Pigs; Histamine Release; In Vitro Techniques; Kidney; Lactones; Male; Ovalbumin; Platelet Activating Factor; Radioimmunoassay; SRS-A; Thromboxane B2 | 1990 |
Interactions between platelet-activating factor and prostanoids during mesenteric ischemia-reperfusion-induced shock in the anesthetized dog.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Dinoprost; Diterpenes; Dogs; Ginkgolides; Hemodynamics; Indomethacin; Lactones; Male; Mesenteric Arteries; Mesenteric Veins; Platelet Activating Factor; Prostaglandins; Reperfusion Injury; Shock; Thromboxane B2 | 1991 |
The differences in 12-hydroxyeicosatetraenoic acid and thromboxane B2 release from guinea pig platelets.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Antibodies; Blood Platelets; Chromatography, High Pressure Liquid; Collagen; Cross Reactions; Guinea Pigs; Hydroxyeicosatetraenoic Acids; Male; Platelet Activating Factor; Platelet Aggregation; Prostaglandin Endoperoxides, Synthetic; Radioimmunoassay; Thromboxane B2 | 1991 |
Effect of platelet-activating factor on porcine pulmonary blood vessels in vitro.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Azepines; Calcimycin; Diterpenes; Eicosanoids; Ginkgolides; In Vitro Techniques; Lactones; Male; Muscle Contraction; Muscle, Smooth, Vascular; Platelet Activating Factor; Platelet Aggregation Inhibitors; Pulmonary Circulation; Radioimmunoassay; SRS-A; Swine; Thromboxane B2; Triazoles | 1991 |
Mechanisms of thrombocytopenia in the acute phase of antigen-induced arthritis in rabbits.
Topics: Animals; Arthritis, Experimental; Diterpenes; Econazole; Female; Ginkgolides; Indoles; Indomethacin; Lactones; Male; Platelet Activating Factor; Rabbits; Synovial Fluid; Thrombocytopenia; Thromboxane A2; Thromboxane B2 | 1991 |
Influence of aminophylline and ketotifen in comparison to the lipoxygenase inhibitors NDGA and esculetin and the PAF antagonists WEB 2170 [correction of 2107] and BN 52021 on endothelin-1 induced vaso- and bronchoconstriction.
Topics: Aminophylline; Animals; Azepines; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Bronchoconstrictor Agents; Diterpenes; Endothelins; Ginkgolides; Guinea Pigs; Ketotifen; Lactones; Lipoxygenase Inhibitors; Lung; Male; Masoprocol; Platelet Activating Factor; Platelet Aggregation Inhibitors; Theophylline; Thromboxane B2; Triazoles; Umbelliferones; Vasoconstriction; Vasoconstrictor Agents | 1991 |
Arachidonic acid cyclo and lipoxygenase pathways in astroglial cells.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acid; Arachidonic Acids; Astrocytes; Calcimycin; Cells, Cultured; Diglycerides; Eicosanoids; Fatty Acids, Nonesterified; Hydroxyeicosatetraenoic Acids; Lipoxygenase; Platelet Activating Factor; Prostaglandin D2; Prostaglandin-Endoperoxide Synthases; Rats; Thromboxane B2 | 1991 |
Platelet function in the peri-operative period.
Topics: Adult; Aged; beta-Thromboglobulin; Blood Platelets; Female; Hemostasis; Humans; Male; Middle Aged; Platelet Activating Factor; Platelet Count; Surgical Procedures, Operative; Thromboxane B2 | 1991 |
The relationship between cytosolic Ca2+, sn-1,2-diacylglycerol and inositol 1,4,5-trisphosphate elevation in platelet-activating-factor-stimulated rabbit platelets. Influence of protein kinase C on production of signal molecules.
Topics: Alkaloids; Animals; Blood Platelets; Calcium; Cytosol; Diglycerides; Dose-Response Relationship, Drug; Homeostasis; Inositol 1,4,5-Trisphosphate; Kinetics; Phosphorylation; Platelet Activating Factor; Platelet Activation; Protein Kinase C; Rabbits; Staurosporine; Thromboxane B2 | 1991 |
Thrombin-induced leukopenia and thrombocytopenia are attenuated by PAF antagonist WEB 2086.
Topics: Animals; Azepines; Carbon Dioxide; Cell Adhesion; Leukocyte Count; Leukopenia; Platelet Activating Factor; Sheep; Thrombin; Thrombocytopenia; Thromboxane B2; Triazoles | 1991 |
Leukotrienes in brain: natural occurrence and induced changes.
Topics: Administration, Oral; Animals; Arachidonic Acid; Body Temperature; Brain Chemistry; Cats; Cerebrospinal Fluid; Cerebrospinal Fluid Proteins; Cyclooxygenase Inhibitors; Dinoprostone; Female; In Vitro Techniques; Injections, Intraventricular; Leukotrienes; Lipoxygenase Inhibitors; Male; Platelet Activating Factor; Pyrogens; Radioimmunoassay; Thromboxane B2 | 1991 |
The involvement of platelet-activating factor in hyperacute xenogeneic rejection and its modulation by the PAF-antagonist WEB 2086BS.
Topics: 6-Ketoprostaglandin F1 alpha; Acute Disease; Animals; Azepines; Female; Graft Rejection; Hemoperfusion; Humans; Kidney Transplantation; Male; Platelet Activating Factor; Swine; Thromboxane B2; Transplantation, Heterologous; Triazoles | 1991 |
Increased platelet turnover in a patient with previous recurrent pre-eclampsia and failure of aspirin therapy. Case report.
Topics: Adult; Aspirin; Blood Platelets; Female; Humans; Platelet Activating Factor; Platelet Aggregation; Pre-Eclampsia; Pregnancy; Thromboxane B2 | 1991 |
Platelet activating factor involvement in splanchnic artery occlusion shock in rats.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arterial Occlusive Diseases; Blood Pressure; Furans; Leukocyte Count; Leukopenia; Macrophages; Male; Phagocytosis; Platelet Activating Factor; Radioimmunoassay; Rats; Rats, Inbred Strains; Shock; Splanchnic Circulation; Thromboxane B2; Tumor Necrosis Factor-alpha | 1991 |
Lipopolysaccharide from Escherichia coli reduces antigen-induced bronchoconstriction in actively sensitized guinea pigs.
Topics: Animals; Antigens; Aspirin; Bronchoconstriction; Cell Degranulation; Endotoxins; Escherichia coli; Guinea Pigs; Hemodynamics; Histamine; Hypersensitivity; Leukopenia; Lipopolysaccharides; Mast Cells; Microscopy, Electron; N-Formylmethionine Leucyl-Phenylalanine; Ovalbumin; Platelet Activating Factor; Pyrilamine; Thromboxane B2 | 1991 |
Platelet-activating factor (PAF) inhibitory profile of KO-286011 on blood platelets in vitro and in vivo.
Topics: Animals; Blood Platelets; Diterpenes; Dose-Response Relationship, Drug; Ginkgolides; Guinea Pigs; Humans; Injections, Intravenous; Lactones; Male; Phospholipid Ethers; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Pyridinium Compounds; Rabbits; Serotonin; Thromboxane B2 | 1990 |
Thromboxane mediates the renal hemodynamic effects of platelet activating factor.
Topics: Animals; Blood Pressure; Drug Interactions; Glomerular Filtration Rate; Hematocrit; Indomethacin; Kidney; Male; Phenylacetates; Platelet Activating Factor; Rats; Rats, Inbred Strains; Receptors, Prostaglandin; Receptors, Thromboxane; Renal Circulation; Sulfonamides; Thromboxane B2 | 1990 |
Thromboxane release by lymphokine-differentiated U937 human monocytic cells: response to platelet-activating factor (PAF) and chemotactic peptide (FMLP) but not to low affinity IGE-receptor (Fc epsilon RII/CD23) occupation.
Topics: Antibodies, Anti-Idiotypic; Antigens, Differentiation, B-Lymphocyte; Calcimycin; Drug Synergism; Humans; Immunoglobulin E; Interferon-gamma; Interleukin-4; Leukemia, Monocytic, Acute; Lymphokines; N-Formylmethionine Leucyl-Phenylalanine; Platelet Activating Factor; Protein Binding; Receptors, Fc; Receptors, IgE; Tetradecanoylphorbol Acetate; Thromboxane B2; Tumor Cells, Cultured | 1990 |
Role of spermatozoal platelet-activating factor in fertilization.
Topics: Animals; Arachidonic Acids; Azepines; Chromatography, High Pressure Liquid; Female; Fertilization; Fertilization in Vitro; Humans; Leukotriene B4; Lipoxygenase; Male; Mice; Platelet Activating Factor; Pregnancy; Prostaglandins F; Sperm Motility; Spermatozoa; Thromboxane B2; Triazines; Triazoles | 1990 |
Platelet activation by polymorphonuclear leukocytes exposed to chemotactic agents.
Topics: Blood Platelets; Calcium; Cell Aggregation; Cytoplasm; Humans; Leukocyte Count; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Thromboxane B2; Time Factors | 1990 |
Platelet activating factor stimulates cyclo-oxygenase activity in guinea pig eosinophils. Concerted biosynthesis of thromboxane A2 and E-series prostaglandins.
Topics: Animals; Azepines; Calcimycin; Calcium; Complement C5a; Cyclooxygenase Inhibitors; Enzyme Activation; Eosinophils; Flurbiprofen; Guinea Pigs; Imidazoles; In Vitro Techniques; N-Formylmethionine Leucyl-Phenylalanine; Platelet Activating Factor; Platelet Membrane Glycoproteins; Prostaglandin-Endoperoxide Synthases; Prostaglandins E; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Superoxides; Tetradecanoylphorbol Acetate; Thromboxane A2; Thromboxane B2; Thromboxane-A Synthase; Triazines; Triazoles | 1990 |
Protection by nedocromil sodium of active immunization-induced bronchopulmonary alterations in the guinea pig.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Bronchi; Bronchoalveolar Lavage Fluid; Constriction, Pathologic; Eosinophils; Female; Guinea Pigs; In Vitro Techniques; Indomethacin; Leukotriene Antagonists; Leukotrienes; Male; Nedocromil; Ovalbumin; Platelet Activating Factor; Quinolones; Respiratory Hypersensitivity; Thromboxane B2 | 1990 |
Inhibition of leukotriene and platelet activating factor synthesis in leukocytes by the sesquiterpene lactone scandenolide.
Topics: Animals; Hydroxyeicosatetraenoic Acids; In Vitro Techniques; Lactones; Leukotriene B4; Plants, Medicinal; Platelet Activating Factor; Rats; Sesquiterpenes; Thromboxane B2 | 1990 |
Calcium ionophore potentiates chemotactic peptide and platelet activating factor in stimulating thromboxane B2 and leukotriene B4 biosynthesis in human neutrophils.
Topics: Calcimycin; Drug Synergism; Humans; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Radioimmunoassay; Tetradecanoylphorbol Acetate; Thromboxane B2 | 1990 |
Inhibition of thrombin- and collagen-induced phosphoinositides breakdown in rabbit platelets by a PAF antagonist--denudatin B, an isomer of kadsurenone.
Topics: Animals; Benzofurans; Blood Platelets; Calcium; Collagen; In Vitro Techniques; Lignans; Molecular Structure; Phosphatidylinositols; Platelet Activating Factor; Platelet Aggregation; Rabbits; Stereoisomerism; Thrombin; Thromboxane B2 | 1990 |
Effect of a thromboxane A2 synthetase inhibitor (OKY-046.HCl) on airway hyperresponsiveness in guinea pigs.
Topics: 6-Ketoprostaglandin F1 alpha; Acetylcholine; Airway Resistance; Animals; Antigens; Aspirin; Bronchoalveolar Lavage Fluid; Guinea Pigs; Leukotriene E4; Methacrylates; N-Formylmethionine Leucyl-Phenylalanine; Phthalazines; Physostigmine; Platelet Activating Factor; Propranolol; Respiratory System; SRS-A; Thromboxane B2; Thromboxane-A Synthase | 1990 |
Regulation of platelet-activating factor receptor and platelet-activating factor receptor-mediated biological responses by cAMP in rat Kupffer cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Bucladesine; Cells, Cultured; Colforsin; Cyclic AMP; Dinoprostone; Isoproterenol; Kinetics; Kupffer Cells; Phenylephrine; Platelet Activating Factor; Platelet Membrane Glycoproteins; Rats; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Thromboxane B2 | 1990 |
Leukocyte and platelet function and eicosanoid production in subjects with hypercholesterolaemia.
Topics: Adenosine Diphosphate; Adult; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Calcimycin; Collagen; Fatty Acids; Female; Humans; Hyperlipoproteinemia Type II; Leukotriene B4; Lipids; Luminescent Measurements; Male; Neutrophils; Platelet Activating Factor; Platelet Aggregation; Serotonin; Thromboxane B2 | 1990 |
Platelet activating factor receptor antagonist improves survival and attenuates eicosanoid release in severe endotoxemia.
Topics: Animals; Dinoprostone; Diterpenes; Endotoxins; Escherichia coli; Ginkgolides; Lactones; Male; Plant Extracts; Platelet Activating Factor; Rats; Rats, Inbred Strains; Shock, Septic; Thromboxane B2 | 1990 |
Evidence that peptidoleukotriene is a prerequisite for antigen-dependent thromboxane synthesis in IgG1-passively sensitized guinea pig lungs.
Topics: Animals; Antigens; Guinea Pigs; Immunoglobulin G; Indazoles; Isoxazoles; Lung; Male; Platelet Activating Factor; SRS-A; Thromboxane B2 | 1990 |
Endothelin-1 and platelet activating factor stimulate thromboxane A2 biosynthesis in rat vascular smooth muscle cells.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Calcium; Cells, Cultured; Dexamethasone; Endothelins; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Rats; Rats, Inbred Strains; Thromboxane A2; Thromboxane B2 | 1990 |
Aggregating platelets increase intracellular calcium in endothelial cells through release of adenine nucleotides.
Topics: Adenine Nucleotides; Calcium; Cells, Cultured; Cytoplasm; Endothelium, Vascular; Humans; In Vitro Techniques; Platelet Activating Factor; Platelet Aggregation; Thromboxane B2 | 1990 |
The booster injection of antigen during active sensitization of guinea-pig modifies the anti-anaphylactic activity of the PAF antagonist WEB 2086.
Topics: Anaphylaxis; Animals; Azepines; Blood Cell Count; Bronchi; Enzyme-Linked Immunosorbent Assay; Guinea Pigs; Histamine; Immunization, Secondary; Immunoglobulin G; Lung; Ovalbumin; Platelet Activating Factor; Radioimmunoassay; Spectrometry, Fluorescence; Thromboxane B2; Triazoles | 1990 |
Protective effect of BN 50739, a new platelet-activating factor antagonist, in endotoxin-treated rabbits.
Topics: Animals; Azepines; Blood Cell Count; Endotoxins; Leukopenia; Male; Platelet Activating Factor; Rabbits; Thrombocytopenia; Thromboxane B2; Triazoles | 1990 |
Biological responses to liposome-encapsulated hemoglobin (LEH) are improved by a PAF antagonist.
Topics: Animals; Azepines; Blood Substitutes; Chemical Phenomena; Chemistry, Physical; Drug Interactions; Hemodynamics; Hemoglobins; Leukocyte Count; Liposomes; Male; Oxygen; Phosphatidylcholines; Platelet Activating Factor; Platelet Count; Rats; Rats, Inbred Strains; Thromboxane B2; Triazoles | 1990 |
Interference of the PAF-acether antagonist BN 52021 with passive anaphylaxis in the guinea-pig.
Topics: Airway Resistance; Anaphylaxis; Animals; Diterpenes; Female; Ginkgolides; Guinea Pigs; Histamine Release; In Vitro Techniques; Lactones; Lung; Male; Ovalbumin; Plant Extracts; Platelet Activating Factor; Thromboxane B2 | 1987 |
Significance of lipid mediators in shock states.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Fatty Acids, Unsaturated; In Vitro Techniques; Leukotrienes; Lipid Metabolism; Platelet Activating Factor; Prostaglandins; Shock; Thromboxane B2 | 1989 |
Platelet-activating factor-stimulated hepatic glycogenolysis is not mediated through cyclooxygenase-derived metabolites of arachidonic acid.
Topics: Animals; Arachidonic Acids; Glucose; Ibuprofen; Liver; Liver Circulation; Liver Glycogen; Male; Platelet Activating Factor; Prostaglandin D2; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Inbred Strains; Reference Values; Thromboxane B2; Vascular Resistance | 1989 |
The relationship of insulin antibodies, platelet-fixing immune complexes and platelet-associated IgG to in vitro platelet aggregation and thromboxane B2 synthesis in childhood type 1 (insulin-dependent) diabetes mellitus.
Topics: Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Child; Collagen; Diabetes Mellitus, Type 1; Epinephrine; Female; Humans; Immunoglobulin G; Immunoglobulins; In Vitro Techniques; Insulin Antibodies; Male; Platelet Activating Factor; Platelet Aggregation; Reference Values; Thromboxane B2 | 1989 |
Lipid mediator production by post-implantation rat embryos in vitro.
Topics: Alprostadil; Animals; Cells, Cultured; Dinoprostone; Embryo, Mammalian; Embryonic Development; Female; Gestational Age; Leukotrienes; Lipid Metabolism; Platelet Activating Factor; Pregnancy; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Rats; Rats, Inbred Strains; Thromboxane B2 | 1989 |
Effect of the concentration of Ca2+ in the suspending medium on the responses of human and rabbit platelets to aggregating agents.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Calcium; Collagen; Dose-Response Relationship, Drug; Humans; Platelet Activating Factor; Platelet Aggregation; Rabbits; Thromboxane B2 | 1989 |
Release of cyclooxygenase products from primary cultures of tracheal epithelia of dog and human.
Topics: Animals; Bradykinin; Calcimycin; Cells, Cultured; Dinoprost; Dinoprostone; Dogs; Epithelium; Gas Chromatography-Mass Spectrometry; Humans; Isoproterenol; Kinetics; Platelet Activating Factor; Prostaglandin-Endoperoxide Synthases; Species Specificity; SRS-A; Thromboxane B2; Trachea | 1989 |
Does acute experimental pancreatitis affect blood platelet function?
Topics: Acute Disease; Adenosine Diphosphate; Animals; Arachidonic Acid; Arachidonic Acids; beta-Thromboglobulin; Blood Platelets; Dogs; Hemostasis; In Vitro Techniques; Pancreatitis; Platelet Activating Factor; Platelet Aggregation; Platelet Count; Thromboxane B2 | 1989 |
Release of eicosanoids in rat peritoneal cavity during the Arthus reaction. Effect of the PAF-antagonist BN-52021 and indomethacin.
Topics: Animals; Arthus Reaction; Dinoprostone; Diterpenes; Ginkgolides; Guinea Pigs; Indomethacin; Lactones; Leukotriene B4; Male; Peritoneal Cavity; Platelet Activating Factor; Rats; Rats, Inbred Strains; Thromboxane B2 | 1989 |
Equine peritoneal macrophage production of thromboxane and prostacyclin in response to platelet activating factor and its receptor antagonist SRI 63-441.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Calcimycin; Endotoxins; Epoprostenol; Escherichia coli; Female; Horses; Macrophages; Male; Peritoneal Cavity; Platelet Activating Factor; Platelet Membrane Glycoproteins; Quinolinium Compounds; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Thromboxane A2; Thromboxane B2 | 1989 |
Beta 2-adrenergic agonist regulation of immune aggregate- and platelet-activating factor-stimulated hepatic metabolism.
Topics: Animals; Antigen-Antibody Complex; Bucladesine; Dinoprostone; Glycogen; Isoproterenol; Liver; Male; Platelet Activating Factor; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Thromboxane B2; Vasoconstriction | 1989 |
Inflammatory mediators of experimental colitis in rats.
Topics: Animals; Colitis; Colon; Ethanol; Interleukin-1; Intestinal Mucosa; Leukotriene B4; Male; Peroxidase; Platelet Activating Factor; Rats; Rats, Inbred Strains; Thromboxane B2; Trinitrobenzenesulfonic Acid | 1989 |
Synergism between chemotactic peptide and platelet-activating factor in stimulating thromboxane B2 and leukotriene B4 biosynthesis in human neutrophils.
Topics: Arachidonic Acid; Arachidonic Acids; Humans; In Vitro Techniques; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Thromboxane B2 | 1989 |
Release of eicosanoids in rat peritoneal cavity stimulated with platelet-activating factor (PAF). Effect of the PAF-antagonist BN-52021.
Topics: Animals; Dinoprostone; Diterpenes; Fatty Acids, Unsaturated; Ginkgolides; Lactones; Leukotriene B4; Peritoneal Cavity; Platelet Activating Factor; Rats; Rats, Inbred Strains; Thromboxane B2 | 1989 |
Release of PAF-acether and eicosanoids from guinea-pig alveolar macrophages by FMLP: effect of cyclo-oxygenase and lipoxygenase inhibition.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonate Lipoxygenases; Benzeneacetamides; Cyclooxygenase Inhibitors; Guinea Pigs; Hydroxamic Acids; In Vitro Techniques; Indomethacin; Leukotriene B4; Lipoxygenase Inhibitors; Macrophages; Male; N-Formylmethionine Leucyl-Phenylalanine; Platelet Activating Factor; Pulmonary Alveoli; Pyrazoles; Radioimmunoassay; Thromboxane B2 | 1989 |
Phospholipase A2-mediated release of arachidonic acid in stimulated guinea pig alveolar macrophages: interaction with lipid mediators and cyclic AMP.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acids; Bronchoalveolar Lavage Fluid; Calcimycin; Cyclic AMP; Dinoprostone; Guinea Pigs; Lipid Metabolism; Lipids; Macrophages; N-Formylmethionine Leucyl-Phenylalanine; Phospholipases; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Prostaglandin-Endoperoxide Synthases; Pulmonary Alveoli; Tetradecanoylphorbol Acetate; Thromboxane B2 | 1989 |
Platelet-activating factor and leukotriene biosynthesis in whole blood. A model for the study of transcellular arachidonate metabolism.
Topics: Arachidonic Acids; Humans; Leukotriene B4; Leukotrienes; Models, Biological; Phagocytes; Phagocytosis; Platelet Activating Factor; Thromboxane B2; Zymosan | 1989 |
Characterization of the normal bovine platelet aggregation response.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acids; Cattle; Epinephrine; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Radioimmunoassay; Serotonin; Thrombin; Thromboxane A2; Thromboxane B2 | 1989 |
Platelet aggregation in the Asian elephant is not dependent on thromboxane B2 production.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Collagen; Elephants; Female; Male; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Thromboxane B2; Verapamil | 1989 |
Whole blood aggregation, thromboxane release and the lyso derivative of platelet activating factor in myocardial infarction and unstable angina.
Topics: Adenosine Diphosphate; Aged; Angina Pectoris; Angina, Unstable; Collagen; Female; Humans; Male; Middle Aged; Myocardial Infarction; Platelet Activating Factor; Platelet Aggregation; Thromboxane B2 | 1989 |
Platelet responses to platelet-activating factor are inhibited in alcoholics undergoing alcohol withdrawal.
Topics: Adult; Aged; Alcoholism; Blood Platelets; Calcium; Ethanol; Female; Hemorrhagic Disorders; Humans; Male; Middle Aged; Platelet Activating Factor; Platelet Aggregation; Serotonin; Smoking; Stimulation, Chemical; Substance Withdrawal Syndrome; Thromboxane B2 | 1989 |
The effects of platelet-activating factor on flow rate and eicosanoid release in the isolated perfused rat gastric vascular bed.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Benzofurans; Blood Flow Velocity; Chromatography, High Pressure Liquid; Chromones; Diterpenes; Gastric Mucosa; Ginkgolides; Indomethacin; Lactones; Lipoxygenase Inhibitors; Male; Masoprocol; Platelet Activating Factor; Rats; Rats, Inbred Strains; SRS-A; Stomach; Thromboxane B2 | 1989 |
Influence of the specific antagonist of PAF-acether, BN 52021, on the rejection of murine tail skin allografts and the PAF-acether mortality in mice in particular consideration of the role of TXB2.
Topics: Animals; Diterpenes; Female; Ginkgolides; Graft Survival; Lactones; Mice; Mice, Inbred Strains; Platelet Activating Factor; Skin Transplantation; Thromboxane B2 | 1989 |
Whole blood aggregation and plasma lyso-PAF related to smoking and atherosclerosis.
Topics: Adenosine Diphosphate; Adult; Aged; Arteriosclerosis; Cell Aggregation; Collagen; Humans; Male; Middle Aged; Platelet Activating Factor; Smoking; Thromboxane B2; Vascular Diseases | 1989 |
Anaphylactic release of platelet activating factor acether and eicosanoids from lungs of guinea pigs sensitized to ovalbumin aerosol.
Topics: Anaphylaxis; Animals; Fatty Acids, Unsaturated; Guinea Pigs; Leukotriene B4; Lung; Male; Ovalbumin; Platelet Activating Factor; SRS-A; Thromboxane B2 | 1987 |
Evidence for a role for Na+-H+ exchange in activation of human platelets by PAF.
Topics: Amiloride; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Bridged Bicyclo Compounds, Heterocyclic; Fatty Acids, Unsaturated; Humans; Hydrazines; Indomethacin; Platelet Activating Factor; Platelet Aggregation; Protons; Serotonin; Sodium; Thromboxane A2; Thromboxane B2 | 1987 |
Can the synthesis of platelet-activating factor, a potent vasodilator and pro-aggregatory agent, be altered by dietary marine oils?
Topics: Adult; Blood Platelets; Chromatography, Gas; Diet; Eicosapentaenoic Acid; Fatty Acids; Fish Oils; Humans; Male; Middle Aged; Phospholipids; Platelet Activating Factor; Platelet Aggregation; Thromboxane B2 | 1987 |
Inhibition of the release of prostaglandins, thromboxanes, and leukotrienes from anaphylactic lungs by a platelet-activating factor (PAF) antagonist and its stimulation by PAF.
Topics: 6-Ketoprostaglandin F1 alpha; Anaphylaxis; Animals; Dinoprostone; Fatty Acids, Unsaturated; Guinea Pigs; In Vitro Techniques; Leukotriene B4; Lung; Platelet Activating Factor; Prostaglandins E; SRS-A; Thromboxane B2 | 1987 |
Mechanisms of platelet-activating factor-induced cardiac depression in the isolated perfused rat heart.
Topics: Animals; Heart; In Vitro Techniques; Leukotriene E4; Male; Myocardial Contraction; Perfusion; Platelet Activating Factor; Radioimmunoassay; Rats; Rats, Inbred Strains; SRS-A; Thromboxane B2; Vascular Resistance | 1987 |
Insulin directly reduces platelet sensitivity to aggregating agents. Studies in vitro and in vivo.
Topics: Adenosine Diphosphate; Adult; Arachidonic Acids; Blood Platelets; Collagen; Cyclic AMP; Epinephrine; Humans; In Vitro Techniques; Insulin; Male; Platelet Activating Factor; Platelet Aggregation Inhibitors; Thromboxane B2 | 1988 |
Differential effect of platelet-activating factor (PAF) receptor antagonists on peptide and PAF-stimulated prostaglandin release in unilateral ureteral obstruction.
Topics: Angiotensin II; Animals; Benzofurans; Dinoprostone; Kidney; Lignans; Male; Peptides; Platelet Activating Factor; Platelet Membrane Glycoproteins; Prostaglandins; Prostaglandins E; Rabbits; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Thromboxane B2; Triazolam; Ureteral Obstruction | 1988 |
Pharmacological profile of 48740 R.P., a PAF-acether antagonist.
Topics: Animals; Blood Cell Count; Blood Platelets; Bronchodilator Agents; Guinea Pigs; Humans; In Vitro Techniques; Macrophages; Male; Muscle Contraction; Muscle, Smooth; N-Formylmethionine Leucyl-Phenylalanine; Perfusion; Platelet Activating Factor; Platelet Aggregation; Pulmonary Alveoli; Pyridines; Rabbits; Radioimmunoassay; Superoxides; Thiazoles; Thromboxane B2 | 1988 |
SOD prevents damage and attenuates eicosanoid release in a rabbit model of necrotizing enterocolitis.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Depression, Chemical; Dinoprostone; Disease Models, Animal; Enterocolitis, Pseudomembranous; Leukotriene B4; Leukotrienes; Male; N-Formylmethionine Leucyl-Phenylalanine; Platelet Activating Factor; Prostaglandins; Rabbits; Superoxide Dismutase; Thromboxane B2 | 1988 |
Effect of dietary fish oils on the formation of leukotriene B4 and B5, thromboxane and platelet activating factor by rat leukocytes.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Diet; Eicosapentaenoic Acid; Fatty Acids; Fish Oils; In Vitro Techniques; Leukocytes; Leukotriene B4; Lipoxygenase; Male; Phospholipids; Platelet Activating Factor; Rats; Rats, Inbred Strains; Thromboxane B2; Thromboxanes | 1988 |
Circulatory effects of PAF-acether in newborn piglets.
Topics: 6-Ketoprostaglandin F1 alpha; Acetophenones; Animals; Animals, Newborn; Bridged Bicyclo Compounds, Heterocyclic; Fatty Acids, Unsaturated; Hemodynamics; Hydrazines; Indomethacin; Platelet Activating Factor; Pulmonary Circulation; Pulmonary Wedge Pressure; Swine; Tetrazoles; Thromboxane B2; Vascular Resistance | 1989 |
PAF-induced platelet aggregation and TXB2 formation.
Topics: Aspirin; Humans; Platelet Activating Factor; Platelet Aggregation; Thromboxane B2 | 1989 |
At low extracellular calcium concentration platelet activating factor induces beta-thromboglobulin release from human platelets through thromboxane-endoperoxides formation.
Topics: beta-Thromboglobulin; Blood Platelets; Calcium; Female; Heparin; Hirudins; Humans; Male; Platelet Activating Factor; Platelet Aggregation; Thromboxane B2; Thromboxanes | 1987 |
Aggregating and prostanoid-releasing effects of platelet-activating factor and leukotrienes on human polymorphonuclear leukocytes and platelets.
Topics: Cell Aggregation; Dinoprostone; Humans; Leukotriene B4; Neutrophils; Platelet Activating Factor; Platelet Aggregation; Prostaglandin-Endoperoxide Synthases; Prostaglandins E; SRS-A; Thromboxane B2 | 1985 |
Cyclic blood flow variations induced by platelet-activating factor in stenosed canine coronary arteries despite inhibition of thromboxane synthetase, serotonin receptors, and alpha-adrenergic receptors.
Topics: 6-Ketoprostaglandin F1 alpha; Adrenergic alpha-Antagonists; Animals; Arteriosclerosis; Coronary Circulation; Coronary Disease; Dogs; Hemodynamics; Imidazoles; Male; Platelet Activating Factor; Platelet Aggregation; Serotonin Antagonists; Thromboxane B2 | 1985 |
Beneficial effects of a new potent and specific thromboxane receptor antagonist (SQ-29,548) in vitro and in vivo.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acids; Bridged Bicyclo Compounds, Heterocyclic; Chromatography, Thin Layer; Dose-Response Relationship, Drug; Fatty Acids, Unsaturated; Hydrazines; Lysosomes; Male; Muscle, Smooth, Vascular; Platelet Activating Factor; Platelet Aggregation; Platelet Count; Prostaglandin-Endoperoxide Synthases; Rabbits; Receptors, Cell Surface; Receptors, Prostaglandin; Receptors, Thromboxane; Thromboxane B2; Thromboxane-A Synthase | 1985 |
Synergistic actions of PAF-acether and sodium arachidonate in human platelet aggregation. 1. Studies in normal human platelet rich plasma.
Topics: Adult; Arachidonic Acids; Aspirin; Dose-Response Relationship, Drug; Drug Synergism; Humans; Lipoxygenase Inhibitors; Platelet Activating Factor; Platelet Aggregation; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Thromboxane B2; Time Factors | 1986 |
Interference of BN 52021 (ginkgolide B) with the bronchopulmonary effects of PAF-acether in the guinea-pig.
Topics: Animals; Blood Platelets; Blood Pressure; Bronchi; Diterpenes; Ginkgolides; Guinea Pigs; In Vitro Techniques; Lactones; Leukocytes; Lung; Male; Muscle Contraction; Plant Extracts; Platelet Activating Factor; Superoxides; Thromboxane B2 | 1986 |
Leukotrienes do not modify the effects of PAF on human platelet aggregation.
Topics: Dose-Response Relationship, Drug; Drug Interactions; Humans; Leukotriene B4; Platelet Activating Factor; Platelet Aggregation; SRS-A; Thromboxane B2 | 1987 |
Platelet-activating factor effects on bovine pulmonary artery endothelial cells.
Topics: Adenylyl Cyclases; Animals; Cattle; Dose-Response Relationship, Drug; Endothelium; Epoprostenol; Isoproterenol; Phosphatidylinositols; Platelet Activating Factor; Pulmonary Artery; Tetradecanoylphorbol Acetate; Thromboxane B2 | 1987 |
Influence of the specific antagonist of PAF-acether, BN 52021, and of Ginkgo extract on the rejection of murine tail skin allografts and the PAF-acether mortality in mice in particular consideration of the role of TXB2.
Topics: Animals; Diterpenes; Ginkgolides; Graft Rejection; Lactones; Mice; Plant Extracts; Platelet Activating Factor; Reference Values; Regeneration; Skin; Skin Transplantation; Thromboxane B2; Transplantation, Homologous | 1988 |
Selective inhibition of arachidonic acid metabolite release from human lung tissue by antiinflammatory steroids.
Topics: Anti-Inflammatory Agents; Arachidonic Acid; Arachidonic Acids; Dexamethasone; Humans; Immunoglobulin E; Lung; N-Formylmethionine Leucyl-Phenylalanine; Platelet Activating Factor; Prostaglandin Antagonists; Prostaglandin D2; Prostaglandin-Endoperoxide Synthases; Prostaglandins D; Prostaglandins F; SRS-A; Thromboxane B2 | 1986 |
Synergistic actions of paf-acether and sodium arachidonate in human platelet aggregation. 2. Unexpected results after aspirin intake.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Adenosine; Administration, Oral; Adult; Apyrase; Arachidonic Acids; Aspirin; Catechols; Drug Synergism; Epoprostenol; Humans; Indomethacin; Masoprocol; Platelet Activating Factor; Platelet Aggregation; Pyrazoles; Thromboxane B2; Time Factors; Umbelliferones | 1986 |
Stimulus-aggregation coupling in platelets activated with PAF-acether.
Topics: Arachidonic Acid; Arachidonic Acids; Blood Platelets; Calcium; Cytosol; Fibrinogen; Humans; Kinetics; Molecular Weight; Phosphatidylinositols; Phosphoproteins; Phosphorylation; Platelet Activating Factor; Platelet Aggregation; Temperature; Thromboxane B2 | 1986 |
Inhibitory effects of a novel platelet activating factor (PAF) antagonist (BN 52021) on antigen-induced prostaglandin and thromboxane formation by the guinea pig lung.
Topics: Anaphylaxis; Animals; Arachidonic Acid; Arachidonic Acids; Dinoprostone; Diterpenes; Female; Ginkgolides; Guinea Pigs; In Vitro Techniques; Kinetics; Lactones; Lung; Male; Ovalbumin; Plant Extracts; Platelet Activating Factor; Prostaglandins; Prostaglandins E; Thromboxane B2; Thromboxanes | 1986 |
Platelet aggregation and thromboxane release induced by arachidonic acid, collagen, ADP and platelet-activating factor following low dose acetylsalicylic acid in man.
Topics: Adenosine Diphosphate; Adolescent; Adult; Arachidonic Acid; Arachidonic Acids; Aspirin; Collagen; Dose-Response Relationship, Drug; Female; Humans; Male; Platelet Activating Factor; Platelet Aggregation; Thromboxane B2; Thromboxanes | 1986 |
Protection by two ginkgolides, BN-52020 and BN-52021, against guinea-pig lung anaphylaxis.
Topics: Anaphylaxis; Animals; Arachidonic Acid; Arachidonic Acids; Blood Pressure; Diterpenes; Dose-Response Relationship, Drug; Ginkgolides; Guinea Pigs; Lactones; Lung; Male; Perfusion; Plant Extracts; Platelet Activating Factor; Thromboxane B2 | 1986 |
Antiplatelet effect of butylidenephthalide.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Blood Coagulation Factors; Calcimycin; Collagen; Dinoprostone; Guinea Pigs; Humans; In Vitro Techniques; Phthalic Acids; Phthalic Anhydrides; Platelet Activating Factor; Platelet Aggregation; Prostaglandins E; Rabbits; Thrombin; Thromboxane B2 | 1987 |
Vinca alkaloids inhibit conversion of arachidonic acid to thromboxane by human platelet microsomes: comparison with other microtubule-active drugs.
Topics: Arachidonic Acid; Arachidonic Acids; Blood Platelets; Chromatography, Thin Layer; Cyclooxygenase Inhibitors; Dinoprostone; Humans; In Vitro Techniques; Malondialdehyde; Microsomes; Oxygen Consumption; Platelet Activating Factor; Platelet Aggregation; Prostaglandins E; Thromboxane B2; Vinblastine | 1987 |
Release of prostaglandin E2 and thromboxane B2 by mixed isolated human lung cells.
Topics: Bradykinin; Calcimycin; Cells, Cultured; Dinoprostone; Humans; Immunoenzyme Techniques; Lung; N-Formylmethionine Leucyl-Phenylalanine; Platelet Activating Factor; Prostaglandins E; Tetradecanoylphorbol Acetate; Thromboxane B2 | 1988 |
Why single daily dose of aspirin may not prevent platelet aggregation.
Topics: Adult; Arachidonic Acid; Arachidonic Acids; Aspirin; Collagen; Drug Synergism; Female; Humans; Male; Middle Aged; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Thromboxane B2 | 1988 |
Mechanism of action of platelet-activating factor on guinea-pig lung parenchyma strips.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Guinea Pigs; Immunoenzyme Techniques; Lung; Masoprocol; Methacrylates; Muscle Contraction; Platelet Activating Factor; Pyrazoles; Sulfonamides; Thromboxane A2; Thromboxane B2 | 1988 |
Effects of platelet-activating factor on coronary hemodynamics and coronary venous plasma levels of TXB2, 6-keto-PGF1 alpha, and leukotriene C4 immunoreactivity in the intact domestic pig heart.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Coronary Circulation; Heart; Myocardium; Platelet Activating Factor; SRS-A; Swine; Thromboxane B2; Thromboxanes | 1985 |
[The effect of platelet-activating factor (PAF) inhalation on airway responsiveness in beagles].
Topics: Administration, Inhalation; Airway Resistance; Animals; Bronchoalveolar Lavage Fluid; Dogs; Female; Methacholine Compounds; Platelet Activating Factor; Respiratory Hypersensitivity; Thromboxane B2 | 1988 |
Active immunization induces lung hyperresponsiveness in the guinea pig. Pharmacologic modulation and triggering role of the booster injection.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Bronchial Spasm; Capillary Permeability; Female; Guinea Pigs; Histamine; Immunization; Immunization, Secondary; Kinetics; Lung; Male; Ovalbumin; Perfusion; Platelet Activating Factor; Pulmonary Circulation; Respiratory Hypersensitivity; SRS-A; Thromboxane B2 | 1988 |
BN-52021 protects guinea-pig from heart anaphylaxis.
Topics: Anaphylaxis; Animals; Diterpenes; Ginkgolides; Guinea Pigs; Heart; Heart Rate; Histamine; Lactones; Male; Platelet Activating Factor; Thromboxane B2 | 1988 |
Influence of prostaglandins and PG-analogues on the mortality of PAF-acether in mice and the TXB2 release from human granulocytes.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Dinoprost; Granulocytes; Humans; In Vitro Techniques; Mice; Mice, Inbred Strains; Platelet Activating Factor; Prostaglandins; Prostaglandins, Synthetic; Skin; Species Specificity; Thromboxane B2 | 1988 |
The effect of dietary fish oil and long-term salt loading on blood pressure and eicosanoid metabolism in spontaneously hypertensive rats.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Blood Pressure; Body Weight; Chromatography, Gas; Diet; Eicosanoids; Fatty Acids, Nonesterified; Fish Oils; Hypertension; Male; Platelet Activating Factor; Potassium; Rats; Rats, Inbred SHR; Sodium; Thromboxane B2; Urodynamics | 1988 |
[The effect of a specific antagonist of PAF (CV-3988) on airway hyperresponsiveness induced by ozone exposure in beagles].
Topics: Animals; Bronchi; Dogs; Female; Methacholine Chloride; Methacholine Compounds; Ozone; Phospholipid Ethers; Platelet Activating Factor; Thiazoles; Thromboxane B2 | 1987 |
Glomeruli from ischemic rat kidneys produce increased amounts of platelet activating factor.
Topics: Animals; In Vitro Techniques; Ischemia; Kidney Glomerulus; Kinetics; Platelet Activating Factor; Rats; Reference Values; Renal Circulation; Thromboxane B2 | 1988 |
Pulmonary vascular response to platelet-activating factor in conscious sheep.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Blood Pressure; Cardiac Output; Lymph; Methacrylates; Platelet Activating Factor; Pulmonary Circulation; Reference Values; Sheep; Thromboxane B2; Thromboxane-A Synthase; Vascular Resistance | 1988 |
Whole blood platelet aggregation is not affected by cigarette smoking but is sex-related.
Topics: Adenosine Diphosphate; Adolescent; Adult; Blood Coagulation; Collagen; Female; Humans; Male; Middle Aged; Platelet Activating Factor; Platelet Aggregation; Sex Factors; Smoking; Thromboxane B2 | 1987 |
Pharmacological modulation of PAF-acether-induced pleurisy in rats.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Anti-Inflammatory Agents, Non-Steroidal; Calcium Channel Blockers; Exudates and Transudates; Glucocorticoids; Male; Platelet Activating Factor; Pleurisy; Rats; Rats, Inbred Strains; SRS-A; Thromboxane B2; Time Factors; Vasodilator Agents | 1987 |
Release of leukotriene C4 by isolated, perfused rat small intestine in response to platelet-activating factor.
Topics: Animals; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Chromones; Dinoprostone; Indomethacin; Intestine, Small; Methacrylates; Perfusion; Platelet Activating Factor; Prostaglandins E; Rats; SRS-A; Thromboxane B2; Vasoconstriction | 1986 |
Platelet-activating factor-acether-induced relaxation of guinea pig airway muscle: role of prostaglandin E2 and the epithelium.
Topics: Acetylcholine; Animals; Aspirin; Dinoprostone; Epithelium; Guinea Pigs; Histamine; In Vitro Techniques; Indomethacin; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Norepinephrine; Platelet Activating Factor; Prostaglandins E; Serotonin; SRS-A; Thromboxane B2; Trachea | 1987 |
Characterization of inflammatory mediator release from purified human lung mast cells.
Topics: Antibodies, Anti-Idiotypic; Cell Separation; Histamine; Humans; Immunoglobulin E; Kinetics; Lung; Mast Cells; Platelet Activating Factor; Pneumonia; Prostaglandin D2; Prostaglandins D; SRS-A; Thromboxane B2 | 1986 |
Inhibition of human lymphocyte proliferation and interleukin 2 production by platelet activating factor (PAF-acether): reversal by a specific antagonist, BN 52021.
Topics: Adult; Cells, Cultured; Dinoprostone; Diterpenes; Ginkgolides; Humans; Indomethacin; Interleukin-2; Lactones; Lymphocyte Activation; Lymphocytes; Phytohemagglutinins; Plant Extracts; Platelet Activating Factor; Prostaglandins E; Thromboxane B2 | 1987 |
Prolonged bleeding time, reduced platelet aggregation, altered PAF-acether sensitivity and increased platelet mass are a trait of asthma and hay fever.
Topics: Adenosine Diphosphate; Adult; Asthma; Bleeding Time; Collagen; Female; Humans; Male; Platelet Activating Factor; Platelet Aggregation; Platelet Count; Platelet Function Tests; Rhinitis, Allergic, Seasonal; Thromboxane B2 | 1986 |
Antiasthmatic effects of onions. Inhibition of platelet-activating factor-induced bronchial obstruction by onion oils.
Topics: Allium; Animals; Asthma; Blood Platelets; Bronchial Provocation Tests; Cells, Cultured; Fibroblasts; Guinea Pigs; Humans; Plant Oils; Platelet Activating Factor; Thromboxane B2 | 1987 |
A novel platelet aggregating factor found in a patient with defective collagen-induced platelet aggregation and autoimmune thrombocytopenia.
Topics: Autoimmune Diseases; Blood Coagulation Factors; Blood Platelet Disorders; Collagen; Female; Humans; Immunoglobulin G; Middle Aged; Platelet Activating Factor; Platelet Aggregation; Purpura, Thrombocytopenic; Thrombocytopenia; Thromboxane B2 | 1987 |
Ontogeny of the responsiveness to intravenous platelet-activating factor.
Topics: Aging; Anaphylaxis; Animals; Animals, Newborn; Female; Leukopenia; Lung; Male; Neutrophils; Platelet Activating Factor; Platelet Aggregation; Platelet Factor 4; Rabbits; Thrombocytopenia; Thromboxane B2 | 1987 |
Interference by the novel PAF-acether antagonist WEB 2086 with the bronchopulmonary responses to PAF-acether and to active and passive anaphylactic shock in guinea-pigs.
Topics: Anaphylaxis; Animals; Azepines; Female; Guinea Pigs; Histamine; In Vitro Techniques; Indicators and Reagents; Leukopenia; Male; Passive Cutaneous Anaphylaxis; Platelet Activating Factor; Radioimmunoassay; Respiratory System; Spectrometry, Fluorescence; Thrombocytopenia; Thromboxane B2; Triazines; Triazoles | 1987 |
Dietary fish oils reduce plasma levels of platelet activating factor precursor (lyso-PAF) in rats.
Topics: Animals; Chromatography, Thin Layer; Fatty Acids; Fish Oils; Hypertension; Male; Phospholipases; Platelet Activating Factor; Rabbits; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Thromboxane B2 | 1986 |
CV3988 inhibits in vivo platelet aggregation induced by PAF-acether and collagen.
Topics: Animals; Blood Pressure; Collagen; Male; Phospholipid Ethers; Platelet Activating Factor; Platelet Aggregation; Platelet Count; Rabbits; Rats; Species Specificity; Thiazoles; Thromboxane B2; Time Factors | 1986 |
Vascular responses of platelet-activating factor in the Cebus apella primate and inhibitory profiles of antagonists SRI 63-072 and SRI 63-119.
Topics: Animals; Cebus; Indomethacin; Lung; Macaca mulatta; Male; Papio; Platelet Activating Factor; Platelet Aggregation; Thiazoles; Thrombocytopenia; Thromboxane B2 | 1986 |
Exudative, cellular and humoral reactions to platelet-activating factor (PAF-acether) in the pleural cavity of rats.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Histamine; Kinetics; Leukocyte Count; Male; Platelet Activating Factor; Pleural Effusion; Rats; Rats, Inbred Strains; SRS-A; Thromboxane B2 | 1986 |
Mechanism of PAF-induced platelet aggregation in man.
Topics: Adult; Aspirin; Blood Platelets; Calcium Channel Blockers; Diterpenes; Female; Ginkgolides; Humans; Kinetics; Lactones; Male; Masoprocol; Plant Extracts; Platelet Activating Factor; Platelet Aggregation; Thromboxane B2; Trifluoperazine | 1986 |
Effect of indomethacin and dazoxiben on intravascular platelet aggregation in the anaesthetized rabbit.
Topics: Adenosine Diphosphate; Animals; Collagen; Dose-Response Relationship, Drug; Imidazoles; Indomethacin; Male; Platelet Activating Factor; Platelet Aggregation; Rabbits; Thrombin; Thromboxane B2 | 1986 |
Platelet-activating factor increases lung vascular permeability to protein.
Topics: Animals; Blood Pressure; Capillary Permeability; Cardiac Output; Cattle; Cells, Cultured; Endothelium; Lymph; Meclofenamic Acid; Platelet Activating Factor; Pulmonary Artery; Pulmonary Circulation; Serum Albumin, Bovine; Sheep; Thromboxane B2; Vascular Resistance | 1986 |
Inhibition by AD6 (8-monochloro-3-beta-diethylaminoethyl-4-methyl-7-ethoxycarbonyl methoxy coumarin) of platelet aggregation in dog stenosed coronary artery.
Topics: 6-Ketoprostaglandin F1 alpha; Adenosine Diphosphate; Animals; Chromonar; Collagen; Coronary Disease; Coumarins; Disease Models, Animal; Dogs; Epinephrine; Male; Platelet Activating Factor; Platelet Aggregation; Regional Blood Flow; Thromboxane B2 | 1985 |
Platelet-activating factor is a potent stimulus for renal prostaglandin synthesis: possible significance in unilateral ureteral obstruction.
Topics: Animals; Biological Assay; Dinoprostone; Dose-Response Relationship, Drug; Kidney; Male; Perfusion; Platelet Activating Factor; Prostaglandins; Prostaglandins E; Rabbits; Rats; Stomach; Thromboxane B2; Time Factors; Ureteral Obstruction | 1985 |
Cyclooxygenase inhibition, platelet function, and metabolite formation during chronic sulfinpyrazone dosing.
Topics: Adult; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Cyclooxygenase Inhibitors; Epoprostenol; Humans; Platelet Activating Factor; Platelet Aggregation; Prostaglandin-Endoperoxide Synthases; Sulfinpyrazone; Thromboxane B2 | 1985 |
Amplification of primary response of human platelets to platelet-activating factor: aspirin-sensitive and aspirin-insensitive pathways.
Topics: Arachidonate Lipoxygenases; Aspirin; Blood Platelets; Cyclooxygenase Inhibitors; Drug Resistance; Humans; In Vitro Techniques; Lipoxygenase Inhibitors; Platelet Activating Factor; Platelet Aggregation; Serotonin; Thromboxane B2 | 1985 |
Human platelet aggregation and release reaction induced by platelet activating factor (PAF-acether)--effects of acetylsalicylic acid and external ionized calcium.
Topics: Aspirin; Blood Platelets; Calcium Chloride; Cyclooxygenase Inhibitors; Female; Humans; Male; Platelet Activating Factor; Platelet Aggregation; Serotonin; Thromboxane B2 | 1985 |
Unsaturated platelet-activating factor: influence on aggregation, serotonin release and thromboxane synthesis of human thrombocytes.
Topics: Blood Platelets; Clonidine; Humans; In Vitro Techniques; Male; Platelet Activating Factor; Platelet Aggregation; Serotonin; Structure-Activity Relationship; Thromboxane B2 | 1986 |
Action of platelet-activating factor on type 1 diabetic human platelets.
Topics: Adult; Blood Glucose; Carbon Radioisotopes; Cholesterol; Diabetes Mellitus, Type 1; Epinephrine; Female; Humans; Hydroxyeicosatetraenoic Acids; Male; Middle Aged; Platelet Activating Factor; Platelet Aggregation; Radioimmunoassay; Serotonin; Thromboxane B2; Triglycerides | 1985 |
Regulation of human platelet activation--analysis of cyclooxygenase and cyclic AMP-dependent pathways.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Blood Platelets; Calcimycin; Collagen; Cyclic AMP; Epinephrine; Epoprostenol; Humans; Platelet Activating Factor; Platelet Aggregation; Prostaglandin Endoperoxides, Synthetic; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Serotonin; Thrombin; Thromboxane B2 | 1984 |
Role of endogenous arachidonate metabolites in phospholipid-induced human platelet activation.
Topics: Arachidonic Acids; Blood Platelets; Humans; Lysophospholipids; Phosphatidic Acids; Platelet Activating Factor; Platelet Aggregation; Thromboxane B2 | 1983 |
Acetyl glycerylphosphorylcholine inhibition of prostaglandin I2-stimulated adenosine 3',5'-cyclic monophosphate levels in human platelets. Evidence for thromboxane A2 dependence.
Topics: Blood Platelets; Cyclic AMP; Dose-Response Relationship, Drug; Epoprostenol; Humans; Indomethacin; Lysophosphatidylcholines; Platelet Activating Factor; Platelet Aggregation; Prostaglandins; Thromboxane A2; Thromboxane B2; Thromboxane-A Synthase; Thromboxanes | 1982 |
Acetyl glyceryl ether phosphorylcholine (platelet-activating factor) mediates heightened metabolic activity in macrophages. Studies on PGE, TXB2 and O2- production, spreading, and the influence of calmodulin-inhibitor W-7.
Topics: Animals; Guinea Pigs; Macrophages; Oxygen; Platelet Activating Factor; Prostaglandins E; Sulfonamides; Superoxides; Thromboxane B2; Thromboxanes; Vasodilator Agents | 1983 |
Pathophysiological mechanisms of sudden death induced by platelet activating factor.
Topics: Animals; Anti-Inflammatory Agents; Blood Pressure; Cyclooxygenase Inhibitors; Death, Sudden; In Vitro Techniques; Male; Muscle, Smooth; Muscle, Smooth, Vascular; Platelet Activating Factor; Pulmonary Artery; Rabbits; Respiration; Thromboxane B2; Thromboxane-A Synthase | 1984 |
The influence of PAF on the metabolization of arachidonic acid by human blood platelets.
Topics: Arachidonic Acid; Arachidonic Acids; Blood Platelets; Calcimycin; Collagen; Humans; Kinetics; Malondialdehyde; Platelet Activating Factor; Platelet Aggregation; Thromboxane B2 | 1984 |
Platelet-activating factor raises airway and vascular pressures and induces edema in lungs perfused with platelet-free solution.
Topics: 6-Ketoprostaglandin F1 alpha; Airway Resistance; Animals; Blood Platelets; Female; Guinea Pigs; Indomethacin; Lung; Perfusion; Platelet Activating Factor; Pressure; Pulmonary Edema; Thromboxane B2; Vascular Resistance | 1984 |
Spasmogenic properties of platelet-activating factor: evidence for a direct mechanism in the contractile response of pulmonary tissues.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Aspirin; Blood Platelets; Catechols; Chromones; Dose-Response Relationship, Drug; Guinea Pigs; Indomethacin; Lung; Masoprocol; Muscle Contraction; Muscle, Smooth; Platelet Activating Factor; Rats; Sulfinpyrazone; Thromboxane B2 | 1983 |
Acute circulatory collapse caused by platelet-activating factor (PAF-acether) in dogs.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Blood Pressure; Dogs; Electrocardiography; Endotoxins; Heart; Heart Rate; Myocardium; Oxygen Consumption; Platelet Activating Factor; Shock; Thromboxane B2 | 1983 |
Platelet activating factor (PAF) causes human platelet aggregation through the mechanism of membrane modulation.
Topics: Adenosine Diphosphate; Adult; Arachidonic Acid; Arachidonic Acids; Aspirin; Blood Platelets; Cell Membrane; Epinephrine; Epoprostenol; Humans; Platelet Activating Factor; Platelet Aggregation; Thromboxane B2; Time Factors | 1982 |
Thromboxane B2 (TxB2) release following acetyl glyceryl ether phosphorylcholine (AGEPC) infusion in the rabbit.
Topics: Animals; Blood Platelets; Female; Male; Platelet Activating Factor; Platelet Count; Platelet Factor 4; Rabbits; Serotonin; Thromboxane B2; Thromboxanes | 1983 |
Cardiovascular and sympathetic effects of l-O-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine in conscious SHR and WKY rats.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Dinoprost; Epinephrine; Heart Rate; Hemodynamics; Male; Norepinephrine; Platelet Activating Factor; Prostaglandins F; Rats; Rats, Inbred Strains; Sympathetic Nervous System; Thromboxane B2 | 1982 |
Adrenaline and PAF-acether synergize to trigger cyclooxygenase-independent activation of plasma-free human platelets.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acids; Aspirin; Creatine Kinase; Drug Synergism; Epinephrine; Humans; Phosphocreatine; Platelet Activating Factor; Platelet Aggregation; Rabbits; Stimulation, Chemical; Thromboxane B2 | 1982 |
Activation of rabbit platelet phospholipase and thromboxane synthesis by 1-O-hexadecyl/octadecyl-2-acetyl-sn-glyceryl-3-phosphorylcholine (platelet activating factor).
Topics: Animals; Arachidonic Acids; Blood Platelets; Dose-Response Relationship, Drug; Glycerides; Kinetics; Lysophosphatidylcholines; Phospholipases; Phospholipids; Platelet Activating Factor; Rabbits; Serotonin; Thromboxane B2; Thromboxanes | 1981 |
Acetyl glyceryl ether phosphorylcholine. Intravascular alterations following intravenous infusion into the baboon.
Topics: Animals; Blood Cell Count; Blood Coagulation Factors; Blood Proteins; Hematocrit; Infusions, Parenteral; Lysophosphatidylcholines; Neutropenia; Papio; Platelet Activating Factor; Platelet Factor 4; Species Specificity; Thrombocytopenia; Thromboxane B2; Thromboxanes | 1981 |
Inhibition of carrageenin-induced rat paw oedema by crotapotin, a polypeptide complexed with phospholipase A2.
Topics: 6-Ketoprostaglandin F1 alpha; Administration, Oral; Animals; Arachidonic Acid; Carrageenan; Cell Degranulation; Crotoxin; Disease Models, Animal; Edema; Guinea Pigs; Histamine Release; Humans; Injections, Intraperitoneal; Male; Mast Cells; p-Methoxy-N-methylphenethylamine; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Platelet Aggregation; Rats; Rats, Wistar; Serotonin; Thromboxane B2 | 1995 |
Effects of stroma-free hemoglobin solutions on pulmonary vascular resistance and mediator release in the isolated perfused rabbit lung.
Topics: Animals; Azepines; Catalase; Cattle; Deferoxamine; Diclofenac; Female; Free Radical Scavengers; Hemoglobins; Histamine Release; Iron; Male; Perfusion; Platelet Activating Factor; Pulmonary Circulation; Rabbits; Stimulation, Chemical; Thromboxane B2; Triazoles; Vascular Resistance; Vasoconstriction | 1994 |
Relevance of mediators to cardiac parameters of isolated anaphylactic guinea-pig heart.
Topics: 6-Ketoprostaglandin F1 alpha; Anaphylaxis; Animals; Catecholamines; Eicosanoids; Epinephrine; Guinea Pigs; Heart; Histamine Release; Kinetics; Leukotrienes; Male; Norepinephrine; Ovalbumin; Platelet Activating Factor; Thromboxane B2 | 1995 |
Role of platelet activating factor in kidney transplant rejection in the rat.
Topics: Animals; Diterpenes; Ginkgolides; Glomerular Filtration Rate; Graft Rejection; Kidney; Kidney Transplantation; Lactones; Leukotriene E4; Male; Plant Extracts; Platelet Activating Factor; Rats; Rats, Inbred ACI; Rats, Inbred Strains; Renal Circulation; Thromboxane B2 | 1995 |
Effect of different platelet agonists on intracellular free Ca++ concentrations in human tumor cells: possible role in tumor growth.
Topics: Adenosine Diphosphate; Adult; Blood Coagulation; Blood Platelets; Calcium; Cell Communication; Cell Division; Collagen; HeLa Cells; Humans; Intracellular Fluid; Leukotriene B4; Melanoma; Mesothelioma; Platelet Activating Factor; Platelet Activation; Platelet Aggregation; Platelet-Derived Growth Factor; Thrombin; Thromboxane B2; Tumor Cells, Cultured; Verapamil | 1995 |
Thromboxane A2 and platelet-activating factor decrease in the platelet-mesangial cell interactions.
Topics: Animals; Blood Platelets; Cell Communication; Cells, Cultured; Glomerular Mesangium; Platelet Activating Factor; Rats; Rats, Wistar; Thromboxane A2; Thromboxane B2 | 1995 |
Nicotine inhibits cytokine synthesis by mouse colonic mucosa.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Colitis, Ulcerative; Colon; Cytokines; Dinoprostone; Female; Interleukin-1; Intestinal Mucosa; Leukotriene B4; Leukotriene C4; Mice; Mice, Inbred BALB C; Nicotine; Platelet Activating Factor; Prostaglandins; Thromboxane B2; Tumor Necrosis Factor-alpha | 1995 |
Inhibition by nedocromil sodium of recombinant human interleukin-5-induced lung hyperresponsiveness to platelet-activating factor in actively sensitized guinea pigs.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Chemotaxis, Leukocyte; Eosinophils; Guinea Pigs; Histamine Release; Interleukin-5; Male; Nedocromil; Platelet Activating Factor; Quinolones; Recombinant Proteins; Thromboxane B2 | 1993 |
Compound PCA-4248 interferes with bronchopulmonary anaphylaxis and with in vitro hyperresponsiveness to platelet-activating factor.
Topics: Anaphylaxis; Animals; Blood Cell Count; Bronchial Hyperreactivity; Bronchoconstriction; Dihydropyridines; Female; Guinea Pigs; Histamine Release; Immunization; In Vitro Techniques; Injections, Intravenous; Lung; Male; Platelet Activating Factor; Radioimmunoassay; Thromboxane B2 | 1993 |
Platelet-activating factor mediates trinitrobenzene induced colitis.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Azepines; Colitis; Colon; Dinoprostone; Eicosanoids; Gastrointestinal Contents; Leukotriene B4; Platelet Activating Factor; Rabbits; Second Messenger Systems; Thromboxane B2; Triazoles; Trinitrobenzenesulfonic Acid | 1994 |
Antiplatelet actions of 2-(4-[1-(2-chlorophenyl) piperazinyl]) methyl-2,3-dihydroimidazo[1,2-c]quinazolin-5(6H)-one compound.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Arachidonic Acid; Blood Platelets; Calcium; Collagen; Cyclic AMP; Epinephrine; Fibrinogen; Humans; Imidazoles; Pancreatic Elastase; Phosphatidylinositols; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Prostaglandin Endoperoxides, Synthetic; Quinazolines; Rabbits; Receptors, Cell Surface; Signal Transduction; Thromboxane A2; Thromboxane B2 | 1995 |
In vitro effects of interleukins on human mesangial cells: implications for glomerulonephritis.
Topics: Adolescent; Adult; Cell Division; Cell Size; Cells, Cultured; Child; Glomerular Mesangium; Glomerulonephritis; Humans; Interleukin-1; Interleukin-6; Interleukins; Platelet Activating Factor; Stimulation, Chemical; Superoxides; Thromboxane B2 | 1995 |
A possible role for platelet-activating factor in the hydrogen peroxide-induced TXB2 and PGE2 glomerular synthesis.
Topics: Animals; Cells, Cultured; Dinoprostone; Hydrogen Peroxide; Kidney Glomerulus; Platelet Activating Factor; Rats; Rats, Wistar; Thromboxane B2 | 1995 |
Effect of platelet activating factor antagonist (CV-3988) on 6-keto-PGF1 alpha and thromboxane B2 in dogs with experimental endotoxin-induced shock.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Dog Diseases; Dogs; Hemodynamics; Phospholipid Ethers; Platelet Activating Factor; Shock, Septic; Thromboxane B2 | 1995 |
Altered inflammatory responses in leukotriene-deficient mice.
Topics: Anaphylaxis; Animals; Arachidonate 5-Lipoxygenase; Chemotaxis, Leukocyte; Dinoprostone; Edema; Inflammation; Leukotriene C4; Leukotrienes; Macrophages; Mice; Mice, Knockout; Neutrophils; Platelet Activating Factor; Thromboxane B2 | 1994 |
The effect of Clostridium difficile toxin on colonocyte prostanoid activity.
Topics: 6-Ketoprostaglandin F1 alpha; Bacterial Proteins; Bacterial Toxins; Cell Line, Transformed; Colon; Culture Media; Cyclooxygenase Inhibitors; Dexamethasone; Dinoprostone; Enterotoxins; Enzyme-Linked Immunosorbent Assay; Humans; Indomethacin; Leukotriene B4; Platelet Activating Factor; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Thromboxane B2 | 1994 |
Inflammatory chemical mediators during conventional ventilation and during high frequency oscillatory ventilation.
Topics: 6-Ketoprostaglandin F1 alpha; Analysis of Variance; Animals; Bronchoalveolar Lavage Fluid; High-Frequency Ventilation; Inflammation Mediators; Leukocyte Count; Lung Compliance; Male; Neutrophils; Platelet Activating Factor; Pulmonary Surfactants; Rabbits; Respiration, Artificial; Thromboxane B2 | 1994 |
[Effects of platelet activating factor on release of thromboxane B2 from human granulocytes and platelets].
Topics: Blood Platelets; Cells, Cultured; Granulocytes; Humans; Male; Platelet Activating Factor; Thromboxane B2 | 1994 |
Eicosanoid and inositol phosphate response to platelet-activating factor (PAF) and to a PAF antagonist in rat astroglial cells.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Animals, Newborn; Astrocytes; Calcimycin; Cells, Cultured; Diterpenes; Dose-Response Relationship, Drug; Eicosanoids; Ginkgolides; Inositol; Inositol Phosphates; Kinetics; Lactones; Platelet Activating Factor; Rats; Thromboxane B2 | 1994 |
Influence of co-incubation and cell number of platelets and polymorphonuclear leukocytes in cellular inhibition and activation phenomena.
Topics: Blood Platelets; Cell Communication; Humans; Leukocyte Count; Neutrophils; Platelet Activating Factor; Platelet Activation; Platelet Aggregation; Platelet Count; Thromboxane A2; Thromboxane B2 | 1994 |
Platelet-activating factor potentiates protamine-induced lung edema. Role of eicosanoids.
Topics: Animals; Arachidonic Acid; Benzoquinones; Constriction, Pathologic; Drug Synergism; Indomethacin; Leukotriene C4; Lipoxygenase Inhibitors; Male; Organ Size; Platelet Activating Factor; Premedication; Prostaglandins F; Protamines; Pulmonary Circulation; Pulmonary Edema; Rats; Rats, Sprague-Dawley; Thromboxane B2; Vascular Resistance | 1994 |
Inhibition of collagen-induced platelet aggregation and adhesion by a pseudocyanide derivative of avicine isolated from Zanthoxylum integrifoliolum Merr.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Arachidonic Acid; Blood Platelets; Calcium; Cell Adhesion; Collagen; Dioxoles; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Inositol Phosphates; Phenanthridines; Platelet Activating Factor; Platelet Aggregation Inhibitors; Prostaglandin D2; Proteoglycans; Rabbits; Structure-Activity Relationship; Thromboxane B2 | 1993 |
Platelet-activating factor as a vasodepressive mediator of liver ischemia.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Ischemia; Isoquinolines; Liver; Male; Molecular Structure; Platelet Activating Factor; Pyridinium Compounds; Rats; Rats, Wistar; Tetrahydroisoquinolines; Thromboxane B2 | 1993 |
Inflammatory mediator changes in cotton-top tamarins (CTT) after SC-41930 anti-colitic therapy.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acids; Benzopyrans; Colitis; Colon; Dinoprostone; Disease Models, Animal; Leukotriene B4; Platelet Activating Factor; Radioimmunoassay; Saguinus; Thromboxane B2 | 1993 |
Lipid mediator production in acute and chronic pancreatitis in the rat.
Topics: 6-Ketoprostaglandin F1 alpha; Acute Disease; Animals; Chronic Disease; Dinoprostone; Diterpenes; Eicosanoids; Ginkgolides; Lactones; Leukotriene B4; Ligation; Male; Masoprocol; Pancreatic Ducts; Pancreatitis; Platelet Activating Factor; Prostaglandin D2; Rats; Rats, Sprague-Dawley; Taurocholic Acid; Thromboxane B2 | 1994 |
Aggregation of killer whale platelets.
Topics: Adaptation, Physiological; Adenosine Diphosphate; Animals; Arachidonic Acid; Blood Platelets; Calcimycin; Collagen; Dolphins; Epinephrine; Female; Male; Platelet Activating Factor; Platelet Aggregation; Ristocetin; Thromboxane B2; Time Factors | 1993 |
CIS-19, a novel platelet activating factor receptor antagonist: in vitro and in vivo studies.
Topics: Adenosine Triphosphate; Animals; Blood Platelets; Bronchoconstriction; Diterpenes; Dose-Response Relationship, Drug; Ginkgolides; Guinea Pigs; Hypotension; Inositol Phosphates; Lactones; Male; Platelet Activating Factor; Rabbits; Rats; Rats, Wistar; Receptors, Cell Surface; Tetrahydronaphthalenes; Thromboxane B2 | 1993 |
Metabolism of arachidonic acid by caruncular and allantochorionic tissues in cows with retained fetal membranes (RFM).
Topics: 6-Ketoprostaglandin F1 alpha; Allantois; Animals; Arachidonic Acid; Calcium; Cattle; Chorion; Chromatography, High Pressure Liquid; Dinoprost; Dinoprostone; Epidermal Growth Factor; Female; Hydroxyeicosatetraenoic Acids; Leukotriene B4; Oxytocin; Placenta; Placenta Diseases; Platelet Activating Factor; Pregnancy; Thromboxane B2 | 1993 |
Administration of a receptor antagonist for platelet-activating factor during equine endotoxaemia.
Topics: Animals; Antithrombin III; Blood Pressure; Body Temperature; Endotoxins; Heart Rate; Hematocrit; Horse Diseases; Horses; Leukocyte Count; Platelet Activating Factor; Platelet Aggregation; Platelet Membrane Glycoproteins; Quinolinium Compounds; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Thromboxane B2; Tumor Necrosis Factor-alpha | 1993 |
Platelet and neutrophil function and eicosanoid release in a subject with abetalipoproteinaemia.
Topics: Abetalipoproteinemia; Adult; Blood Platelets; Eicosanoids; Fatty Acids; Female; Humans; In Vitro Techniques; Leukotriene B4; Lipoproteins, LDL; Luminescent Measurements; Neutrophils; Platelet Activating Factor; Platelet Aggregation; Thromboxane B2 | 1993 |
[Bioassay of Lyso-PAF platelet activating factor and it's role in bronchial asthma].
Topics: Adolescent; Adult; Animals; Asthma; Biological Assay; Female; Guinea Pigs; Humans; Lung; Male; Middle Aged; Ovalbumin; Platelet Activating Factor; Thromboxane B2 | 1993 |
Effect of 5-lipoxygenase and cyclooxygenase blockade on porcine hemodynamics during continuous infusion of platelet-activating factor.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Azepines; Blood; Calcimycin; Chromatography, High Pressure Liquid; Cyclooxygenase Inhibitors; Hemodynamics; Hypertension, Pulmonary; In Vitro Techniques; Indomethacin; Infusions, Intra-Arterial; Leukotriene B4; Lipoxygenase Inhibitors; Naphthoquinones; ortho-Aminobenzoates; Platelet Activating Factor; Swine; Thromboxane B2; Triazoles | 1993 |
Pertussis toxin attenuates platelet-activating factor-induced pulmonary hemodynamic alterations in pigs.
Topics: Animals; Blood Platelets; Calcimycin; GTP-Binding Proteins; Hemodynamics; Indomethacin; Injections, Intravenous; Lung; Pertussis Toxin; Phosphorylation; Platelet Activating Factor; Prostaglandin-Endoperoxide Synthases; Sodium Chloride; Swine; Thrombocytopenia; Thromboxane B2; Time Factors; Vasoconstriction; Virulence Factors, Bordetella | 1993 |
Cytokine mRNA expression by cultured rat mesangial cells after contact with environmental lectins.
Topics: Animals; Cells, Cultured; Cytokines; Dinoprostone; Gene Expression; Genes, fos; Genes, myc; Gliadin; Glomerular Mesangium; Interleukin-1; Interleukin-6; Lectins; Platelet Activating Factor; Rats; RNA, Messenger; Thromboxane B2; Tumor Necrosis Factor-alpha | 1993 |
Platelet-activating factor-induced human eosinophil activation. Generation and release of cyclo-oxygenase metabolites in human blood eosinophils from asthmatics.
Topics: Asthma; Cells, Cultured; Dose-Response Relationship, Drug; Eosinophils; Humans; Ibuprofen; Leukocytes; Platelet Activating Factor; Prostaglandins; Thromboxane B2 | 1993 |
11-Dehydro thromboxane B2: a reliable parameter of thromboxane A2 production in dogs.
Topics: Animals; Dogs; Female; Lung; Male; Platelet Activating Factor; Reproducibility of Results; Thromboxane A2; Thromboxane B2; Vascular Resistance | 1993 |
ARDS-like lung injury produced by endotoxin in platelet-activating factor-primed rats.
Topics: Animals; Disease Models, Animal; Endotoxins; Hemodynamics; Lipopolysaccharides; Lung; Lung Injury; Male; Microscopy, Electron; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Respiratory Distress Syndrome; Thromboxane B2; Tumor Necrosis Factor-alpha | 1993 |
Platelet activating factor (PAF) stimulates release of PGI2 from inflamed rabbit gallbladder cell cultures.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Antibodies; Cells, Cultured; Cholecystitis; Cytochrome P-450 Enzyme System; Dinoprost; Dose-Response Relationship, Drug; Epoprostenol; Gallbladder; Immunoblotting; Indomethacin; Intramolecular Oxidoreductases; Isomerases; Platelet Activating Factor; Prostaglandin-Endoperoxide Synthases; Proteins; Rabbits; Thromboxane B2 | 1995 |
Delayed elevation of platelet activating factor in ischemic hippocampus.
Topics: Analysis of Variance; Animals; Hippocampus; Ischemic Attack, Transient; Male; Microdialysis; Pilot Projects; Platelet Activating Factor; Rats; Rats, Wistar; Reaction Time; Reperfusion; Thromboxane B2 | 1995 |
Evidence for altered cellular calcium in the pathogenetic mechanism of acute pancreatitis in rats.
Topics: Acute Disease; Animals; Calcium; Calcium Channel Blockers; Ceruletide; Drug Synergism; Male; Pancreas; Pancreatitis; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Thromboxane B2; Verapamil | 1996 |
KW-4679, an antiallergic drug, inhibits the production of inflammatory lipids in human polymorphonuclear leukocytes and guinea pig eosinophils.
Topics: Acetyltransferases; Animals; Anti-Allergic Agents; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Autacoids; Dibenzoxepins; Enzyme Activation; Eosinophils; Guinea Pigs; Humans; Leukotriene B4; Lipids; Lipoxygenase Inhibitors; Male; Neutrophils; Olopatadine Hydrochloride; Platelet Activating Factor; Thromboxane B2; Thromboxane-A Synthase | 1996 |
A higher production of platelet activating factor in ex vivo heterologously secondary dengue-2 virus infections.
Topics: Dengue; Humans; Platelet Activating Factor; Prostaglandin D2; Thromboxane B2 | 1995 |
Attenuation of endotoxin-induced pathophysiology by a new potent PAF receptor antagonist.
Topics: Animals; Blood Pressure; Cardiac Output; Dose-Response Relationship, Drug; Lipopolysaccharides; Lung; Peroxidase; Platelet Activating Factor; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Prodrugs; Pyridinium Compounds; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Shock, Septic; Stroke Volume; Swine; Thiazoles; Thromboxane B2; Vascular Resistance | 1996 |
[Effects of platelet activating factor and platelet activating factor receptor antagonist on spinal cord blood flow after spinal cord injury].
Topics: Animals; Cats; Diterpenes; Female; Ginkgolides; Injections, Spinal; Lactones; Male; Platelet Activating Factor; Prostaglandins F; Regional Blood Flow; Spinal Cord; Spinal Cord Injuries; Thromboxane B2 | 1995 |
Platelet-activating factor and arachidonic acid metabolites in psoriatic inflammation.
Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Adolescent; Adult; Aged; Arachidonic Acid; Child; Dinoprostone; Female; Humans; Leukotrienes; Male; Middle Aged; Phospholipases A; Platelet Activating Factor; Psoriasis; Thromboxane B2 | 1996 |
Sephadex G-200-induced eosinophil infiltration into airways in non-sensitized and sensitized guinea pigs, and responsiveness of the cells to stimuli in vitro.
Topics: Aluminum Hydroxide; Animals; Antigens; Bronchoalveolar Lavage Fluid; Calcimycin; Dextrans; Eosinophils; Gels; Guinea Pigs; Indicators and Reagents; Inflammation; Injections, Intraperitoneal; Injections, Intravenous; Ionophores; Leukocyte Count; Leukotriene B4; Male; Passive Cutaneous Anaphylaxis; Platelet Activating Factor; Respiratory System; Superoxides; Thromboxane B2 | 1996 |
Cyclooxygenase-2-dependent bronchoconstriction in perfused rat lungs exposed to endotoxin.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 6-Ketoprostaglandin F1 alpha; Animals; Bronchoconstriction; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; DNA Primers; Endotoxins; Female; In Vitro Techniques; Isoenzymes; Lipopolysaccharides; Lipoxygenase Inhibitors; Lung; Microscopy, Electron, Scanning; Platelet Activating Factor; Polymerase Chain Reaction; Prostaglandin Endoperoxides, Synthetic; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar; RNA, Messenger; Salmonella; Thromboxane A2; Thromboxane B2; Transcription, Genetic; Vasoconstrictor Agents | 1996 |
Biochemical and cellular effects of heparin-protamine injection in rabbits are partially inhibited by a PAF-acether receptor antagonist.
Topics: Animals; Anticoagulants; Cyclooxygenase Inhibitors; Diterpenes; Fibrinolytic Agents; Ginkgolides; Heparin; Heparin Antagonists; Indomethacin; Infusions, Intravenous; Lactones; Platelet Activating Factor; Protamines; Rabbits; Thromboxane B2 | 1996 |
Effects of platelet-activating factor antagonist E5880 on intrahepatic and systemic metabolic responses to transient hepatic inflow occlusion and reperfusion in the rabbit.
Topics: 6-Ketoprostaglandin F1 alpha; Adenine Nucleotides; Ammonia; Analysis of Variance; Animals; Blood Gas Analysis; Blood Glucose; Energy Metabolism; Hydrogen-Ion Concentration; Lactic Acid; Liver; Male; Piperidines; Platelet Activating Factor; Pyridinium Compounds; Pyruvic Acid; Rabbits; Reperfusion Injury; Thromboxane B2 | 1996 |
Influence of heat shock protein 70 and metallothionein induction by zinc-bis-(DL-hydrogenaspartate) on the release of inflammatory mediators in a porcine model of recurrent endotoxemia.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Aspartic Acid; Blood Pressure; Cardiac Output; Disease Models, Animal; Endotoxemia; Gene Expression; HSP70 Heat-Shock Proteins; Inflammation Mediators; Interleukin-1; Interleukin-6; Kidney; Lipopolysaccharides; Metallothionein; Platelet Activating Factor; Pulmonary Artery; Recurrence; Swine; Thromboxane B2; Tumor Necrosis Factor-alpha; Zinc | 1996 |
PAF modulates eicosanoids and TNF release in immune-complex arthritis in rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Arthus Reaction; Cattle; Dinoprostone; Eicosanoids; Indoles; Indomethacin; Injections, Intra-Articular; Leukotriene B4; Lipoxygenase Inhibitors; Male; Platelet Activating Factor; Rabbits; Rats; Rats, Wistar; Synovial Fluid; Thromboxane B2; Tumor Necrosis Factor-alpha | 1997 |
Postural vasoregulation and mediators of reperfusion injury in venous ulceration.
Topics: Aged; Aged, 80 and over; Blood Pressure; Cytokines; Humans; Interleukin-1; Interleukin-6; Ischemia; Laser-Doppler Flowmetry; Leg; Leukotriene B4; Microcirculation; Middle Aged; P-Selectin; Platelet Activating Factor; Plethysmography, Impedance; Posture; Receptors, Interleukin-1; Regional Blood Flow; Reperfusion Injury; Thromboxane B2; Treatment Outcome; Tumor Necrosis Factor-alpha; Varicose Ulcer; Vasomotor System; Wound Healing | 1997 |
Antiplatelet effects of some aporphine and phenanthrene alkaloids in rabbits and man.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Aporphines; Arachidonic Acid; Blood Platelets; Collagen; Cyclic AMP; Guaiacol; Humans; Isoquinolines; Isotope Labeling; Lipoxygenase Inhibitors; Male; Phenanthrenes; Platelet Activating Factor; Platelet Aggregation Inhibitors; Quinolines; Rabbits; Radioimmunoassay; Structure-Activity Relationship; Thrombin; Thromboxane B2; Vasoconstrictor Agents | 1997 |
Changes in inflammatory mediators during orthotopic liver transplantation.
Topics: Adult; Cytokines; Female; Hemodynamics; Humans; Inflammation Mediators; Intraoperative Period; Leukotrienes; Liver Transplantation; Male; Middle Aged; Platelet Activating Factor; Reperfusion; Thromboxane B2 | 1997 |
Protein kinase C inhibition enhances platelet-activating factor-induced eicosanoid production in human eosinophils.
Topics: Arachidonic Acid; Calcium; Catalase; Eicosanoids; Enzyme Inhibitors; Eosinophils; Female; Humans; Indoles; Leukotriene C4; Male; Maleimides; Naphthalenes; Phorbol 12,13-Dibutyrate; Platelet Activating Factor; Protein Kinase C; Respiratory Burst; Superoxides; Tetradecanoylphorbol Acetate; Thromboxane B2 | 1998 |
Role of lipid-derived mediators in tumor necrosis factor-induced endothelin-1 release in vivo.
Topics: Animals; Arachidonic Acid; Endothelin-1; Heart; Lipids; Lung; Platelet Activating Factor; Prostaglandin-Endoperoxide Synthases; Recombinant Proteins; Swine; Thromboxane B2; Tumor Necrosis Factor-alpha | 1998 |
Macrophages that have ingested apoptotic cells in vitro inhibit proinflammatory cytokine production through autocrine/paracrine mechanisms involving TGF-beta, PGE2, and PAF.
Topics: Apoptosis; Cytokines; Dinoprostone; Humans; Inflammation; Jurkat Cells; Leukotriene C4; Macrophages; Neutrophils; Phagocytosis; Platelet Activating Factor; Solubility; Thromboxane B2; Transforming Growth Factor beta | 1998 |
Expression of acute otitis media after receptor blockade of platelet activating factor, thromboxane, and leukotrienes in the chinchilla.
Topics: 6-Ketoprostaglandin F1 alpha; Acute Disease; Animals; Azepines; Biphenyl Compounds; Chinchilla; Dinoprostone; Ear, Middle; Fatty Acids, Nonesterified; Heptanoic Acids; Hydrolases; Leukotriene Antagonists; Leukotriene C4; Mucous Membrane; Otitis Media; Phospholipids; Platelet Activating Factor; Platelet Membrane Glycoproteins; Pneumococcal Infections; Propionates; Quinolines; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Receptors, Thromboxane; Thromboxane B2; Triazoles | 1998 |
Antiplatelet action of 3',4'-diisovalerylkhellactone diester purified from Peucedanum japonicum Thunb.
Topics: Adenosine Triphosphate; Animals; Apiaceae; Blood Platelets; Calcium; Coumarins; In Vitro Techniques; Phosphatidylinositols; Plant Roots; Plants, Medicinal; Platelet Activating Factor; Platelet Aggregation Inhibitors; Prostaglandins; Rabbits; Thromboxane B2 | 1998 |
[The relationship between the activity of phospholipase A2 and acute hypoxic pulmonary arterial pressure].
Topics: Animals; Dinoprostone; Female; Hypertension, Pulmonary; Hypoxia; Male; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Random Allocation; Rats; Rats, Sprague-Dawley; Thromboxane B2 | 1997 |
Mepyramine inhibits platelet activating factor-induced rabbit platelet aggregation: role of intracellular histamine.
Topics: Animals; Blood Platelets; Calcium; Histamine; Histamine H1 Antagonists; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Pyrilamine; Rabbits; Thromboxane B2 | 1997 |
Are lipid mediators implicated in the production of pro- and anti-inflammatory cytokines during cardiopulmonary bypass graft with extracorporeal circulation?
Topics: 6-Ketoprostaglandin F1 alpha; Anti-Inflammatory Agents; Cardiopulmonary Bypass; Cytokines; Dinoprostone; Extracorporeal Circulation; Humans; Inflammation Mediators; Interleukin-10; Interleukin-4; Interleukin-6; Interleukin-8; Leukotriene B4; Leukotriene C4; Lipid Metabolism; Lipids; Multiple Organ Failure; Platelet Activating Factor; Prospective Studies; Thromboxane B2; Tumor Necrosis Factor-alpha | 1999 |
Actions and interactions of ADP, 5- HT, histamine and PAF on equine platelets.
Topics: Adenosine Diphosphate; Animals; Blood Platelets; Drug Interactions; Histamine; Horses; Platelet Activating Factor; Platelet Aggregation; Serotonin; Thromboxane B2 | 2000 |
Antiplatelet effect of marchantinquinone, isolated from Reboulia hemisphaerica, in rabbit washed platelets.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Triphosphate; Animals; Arachidonic Acid; Bibenzyls; Blood Platelets; Calcium; Collagen; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Ethers, Cyclic; Phosphatidylinositols; Plants, Medicinal; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Rabbits; Thrombin; Thromboxane B2 | 2000 |
Differential activation of platelets from normal and allergic ponies by PAF and ADP.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Adenosine Diphosphate; Animals; Dermatitis, Contact; Eicosanoids; Horse Diseases; Horses; Hypersensitivity, Immediate; Platelet Activating Factor; Platelet Activation; Seasons; Serotonin; Signal Transduction; Thromboxane B2 | 2000 |
Amifostine, a reactive oxigen species scavenger with radiation- and chemo-protective properties, inhibits in vitro platelet activation induced by ADP, collagen or PAF.
Topics: Adenosine Diphosphate; Adult; Amifostine; Antioxidants; Blood Platelets; Collagen; Dose-Response Relationship, Drug; Free Radical Scavengers; Humans; Nitric Oxide; Oxidative Stress; Platelet Activating Factor; Platelet Activation; Platelet Aggregation Inhibitors; Radiation-Protective Agents; Reactive Oxygen Species; Thromboxane B2 | 2000 |
Preventive effect of platelet-activating factor antagonist, Y-24180, against cyclosporine-induced acute nephrotoxicity.
Topics: Animals; Azepines; Cyclosporine; Dose-Response Relationship, Drug; Endothelin-1; Hemodynamics; Immunosuppressive Agents; Kidney; Male; Platelet Activating Factor; Rats; Rats, Wistar; Thromboxane B2; Triazoles | 2001 |
Prostaglandin endoperoxides and thromboxane A2 activate the same receptor isoforms in human platelets.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Aspirin; Biphenyl Compounds; Blood Platelets; Bridged Bicyclo Compounds, Heterocyclic; Calcium Signaling; Cells, Cultured; Enzyme Inhibitors; Fatty Acids, Unsaturated; Heptanoic Acids; Humans; Hydrazines; Imidazoles; Inositol Phosphates; Kidney; Methacrylates; Phenylacetates; Platelet Activating Factor; Platelet Activation; Prostaglandin H2; Prostaglandins H; Protein Isoforms; Receptors, Thromboxane; Recombinant Fusion Proteins; Sulfonamides; Thromboxane A2; Thromboxane B2; Thromboxane-A Synthase | 2002 |
E3040 sulphate, a novel thromboxane synthase inhibitor, blocks the Cl- secretion induced by platelet-activating factor in isolated rat colon.
Topics: Animals; Benzothiazoles; Chlorides; Colon; Enzyme Inhibitors; Female; In Vitro Techniques; Intestinal Mucosa; Lipoxygenase Inhibitors; Organic Anion Transporters; Platelet Activating Factor; Prostaglandin-Endoperoxide Synthases; Pyridines; Rats; Rats, Wistar; Thiazoles; Thromboxane B2; Thromboxane-A Synthase | 2002 |
Increased platelet-activating factor-induced periventricular brain microvascular constriction associated with immaturity.
Topics: Aging; Animals; Animals, Newborn; Brain; Calcium; Calcium Channel Blockers; Fetus; Inositol Phosphates; Logistic Models; Platelet Activating Factor; Swine; Thromboxane B2; Vasoconstriction | 2003 |
Sulfur-related air pollutants induce the generation of platelet-activating factor, 5-lipoxygenase- and cyclooxygenase-products in canine alveolar macrophages via activation of phospholipases A2.
Topics: Air Pollutants; Animals; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Autoradiography; Carbon Radioisotopes; Cells, Cultured; Chromatography, Thin Layer; Dinoprostone; Dogs; Enzyme Activation; Fatty Acids, Unsaturated; Hydrogen-Ion Concentration; Hydroxyeicosatetraenoic Acids; Leukotriene B4; Macrophages, Alveolar; Phospholipases A; Platelet Activating Factor; Prostaglandin-Endoperoxide Synthases; Sulfates; Sulfites; Sulfur; Thromboxane B2 | 2003 |
Protective effect of pentoxifylline on volume-induced lung injury in newborn piglets.
Topics: Animals; Animals, Newborn; Anti-Inflammatory Agents; Biomechanical Phenomena; Inflammation; Lung; Lung Diseases; Lung Injury; Pentoxifylline; Peroxidase; Placebos; Platelet Activating Factor; Respiration, Artificial; Swine; Thromboxane B2; Tidal Volume | 2004 |
Platelet aggregation and vasoconstriction related to platelet cyclooxygenase and 12-lipoxygenase pathways.
Topics: Animals; Arachidonate 12-Lipoxygenase; Collagen; Ear; Male; Norepinephrine; Platelet Activating Factor; Platelet Aggregation; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Rabbits; Regional Blood Flow; Thromboxane B2; Tissue Culture Techniques; Vasoconstriction; Vasoconstrictor Agents; Vasodilator Agents | 2005 |
Effect of baicalin on inflammatory mediator levels and microcirculation disturbance in rats with severe acute pancreatitis.
Topics: Acute Disease; Amylases; Animals; Anti-Inflammatory Agents, Non-Steroidal; Ascites; Dinoprostone; Flavonoids; Inflammation Mediators; Interleukin-1beta; Male; Microcirculation; Pancreas; Pancreatitis; Phospholipases A2; Platelet Activating Factor; Random Allocation; Rats; Rats, Sprague-Dawley; Thromboxane B2 | 2009 |
Inhibitory effects of acetylmelodorinol, chrysin and polycarpol from Mitrella kentii on prostaglandin E₂ and Thromboxane B₂ production and platelet activating factor receptor binding.
Topics: Alkenes; Animals; Annonaceae; Blood Platelets; Cyclooxygenase 1; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Flavonoids; Humans; Inhibitory Concentration 50; Plant Extracts; Plant Leaves; Platelet Activating Factor; Platelet Membrane Glycoproteins; Polycyclic Aromatic Hydrocarbons; Rabbits; Radioimmunoassay; Receptors, G-Protein-Coupled; Thromboxane B2 | 2012 |
Anti-platelet activity of erythro-(7S,8R)-7-acetoxy-3,4,3',5'-tetramethoxy-8-O-4'-neolignan from Myristica fragrans.
Topics: Adult; Arachidonic Acid; Blood Platelets; Calcium; Calcium Signaling; Cyclic AMP; Dose-Response Relationship, Drug; Humans; Inhibitory Concentration 50; Lignans; Male; Myristica; Platelet Activating Factor; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Serotonin; Thrombin; Thromboxane B2; Young Adult | 2013 |
Correlations of platelet-derived microparticles with thromboxane B2, platelet-activating factor, endothelin-1, and neutrophil to lymphocyte ratio in patients with coronary intermediate lesions.
Topics: Aged; Biomarkers; Blood Platelets; Coronary Artery Disease; Endothelin-1; Female; Humans; Lymphocyte Count; Male; Middle Aged; Neutrophils; Platelet Activating Factor; Platelet Activation; Thromboxane B2 | 2014 |