1-hexadecyl-2-acetyl-glycero-3-phosphocholine has been researched along with thromboxane a2 in 182 studies
| Studies (1-hexadecyl-2-acetyl-glycero-3-phosphocholine) | Trials (1-hexadecyl-2-acetyl-glycero-3-phosphocholine) | Recent Studies (post-2010) (1-hexadecyl-2-acetyl-glycero-3-phosphocholine) | Studies (thromboxane a2) | Trials (thromboxane a2) | Recent Studies (post-2010) (thromboxane a2) |
|---|---|---|---|---|---|
| 9,156 | 187 | 552 | 5,617 | 224 | 429 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 62 (34.07) | 18.7374 |
| 1990's | 92 (50.55) | 18.2507 |
| 2000's | 26 (14.29) | 29.6817 |
| 2010's | 2 (1.10) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Giessler, C; Mentz, G; Mentz, P; Mest, HJ | 1 |
| Smith, LJ | 1 |
| Babycos, CR; Hood, JS; Ibrahim, IN; Kadowitz, PJ; McMahon, TJ; Nossaman, BD | 1 |
| Armstrong, ML; Densen, P; Heistad, DD; Lopez, JA; Mügge, A; Padgett, RC; Piegors, DJ | 1 |
| Javors, MA; Olson, MS; Zhou, W | 1 |
| Bisogno, G; Galbusera, M; Livio, M; Macconi, D; Orisio, S; Remuzzi, G; Viganò, G | 1 |
| Miura, K; Okumura, M; Yamamoto, K; Yamanaka, S; Yukimura, T | 1 |
| Arata, Y; Kume, S; Tada, S; Ui, M; Yatomi, Y | 1 |
| Eldor, A; Hy-Am, E; Matzner, Y; Orevi, M; Rigbi, M | 1 |
| Bone, RC | 1 |
| Ferro, TJ; Hocking, DC; Johnson, A | 1 |
| Dollery, CT; Fuller, RW; Taylor, GW; Taylor, IK; Ward, PS | 1 |
| Mayeux, PR; Shah, SV; Ueda, N; Walker, PD | 1 |
| Arita, H; Hanasaki, K; Kato, T; Kishino, J | 1 |
| FitzGerald, GA; Murray, R; Shipp, E | 1 |
| Davenport, NJ; Feuerstein, GZ; Goldstein, RE | 1 |
| Deguchi, K; Murashima, S | 1 |
| Calvo, IF; da Rocha, FA; de Falco, V; Fernandes, AJ; Jancar, S; Sirois, P | 1 |
| Bradley, LM; Davenport, NJ; Feuerstein, GZ; Goldstein, RE; Laurindo, FR; Stambouly, JJ | 1 |
| Barros, EJ; Boim, MA; Braquet, P; dos Santos, OF; Pirotzky, E; Schor, N | 1 |
| Barnes, PJ; Chung, KF; Lötvall, JO; Morikawa, A; Tokuyama, K | 1 |
| Chakrabarty, S; Sheridan, DJ; Thomas, P | 1 |
| Klahr, S; Reyes, AA | 1 |
| Dyson, MC; Kadowitz, PJ | 1 |
| Adachi, M; Hiyama, T; Idaira, K; Imai, T; Maeda, M; Saito, C; Suganuma, T; Takahashi, T; Tsuji, A | 1 |
| Bertrand, C; Landry, Y; Tschirhart, E | 1 |
| McCulloch, RK; Vandongen, R | 1 |
| Kambayashi, J; Kawasaki, T; Mori, T; Sakon, M; Shiba, E; Uemura, Y | 1 |
| Alessandri, C; Balsano, F; Cordova, C; Ghiselli, A; Iuliano, L; Pratico, D; Violi, F | 1 |
| Dillon, PK; Durán, WN | 1 |
| Felsen, D; Loo, MH; Marion, DN; Vaughan, ED | 1 |
| Hauser, A; Heinroth-Hoffmann, I; Mest, HJ | 1 |
| Huang, TF; Ko, FN; Liu, YM; Sheu, SJ; Teng, CM | 1 |
| Barnes, PJ; Giembycz, MA; Kroegel, C | 1 |
| Hamano, S; Ikeda, S; Kikuchi, S; Komatsu, H; Okegawa, T; Takehana, Y | 1 |
| Arai, Y; Kawamura, M | 1 |
| Hirafuji, M; Ogura, Y | 1 |
| Kondo, K; Takayasu-Okishio, M; Terashita, Z | 1 |
| Hamano, S; Ikeda, S; Kikuchi, S; Komatsu, H; Kusama, H; Okegawa, T; Takehana, Y | 1 |
| de Chaffoy de Courcelles, D; De Clerck, F | 1 |
| Badr, KF; Blair, I; Christman, BW; Schreiner, GF; Takahashi, K; Yamashita, K | 1 |
| Avdonin, PV; Bochkov, VN; Cheglakov, IB; Tkachuk, VA | 1 |
| Silbaugh, SA; Stengel, PW | 1 |
| Lianos, EA | 1 |
| Boughton-Smith, NK; Hutcheson, I; Whittle, BJ | 1 |
| Alessandri, C; Balsano, F; Ghiselli, A; Guzzo, A; Praticò, D; Violi, F | 1 |
| Piper, PJ; Yaacob, HB | 1 |
| Xiao, HS | 1 |
| Benigni, A; Bertani, T; Livio, M; Macconi, D; Morigi, M; Orisio, S; Patrono, C; Perico, N; Remuzzi, G; Ubiali, A | 1 |
| Moore, JN; Morris, DD | 1 |
| Gerrard, JM; MacIntyre, DE; McNicol, A | 1 |
| Baker, RC; Fish, HT; Fitzpatrick, FA | 1 |
| Bondy, GS; Gentry, PA | 1 |
| Bradley, LM; Czaja, JF; Goldstein, RE; Stambouly, JJ | 1 |
| Kondo, K; Takayasu, M; Terao, S | 1 |
| Ikeda, K; Sasaki, H; Sasaki, T; Shimura, S; Takishima, T | 1 |
| Davenport, NJ; Ezra, D; Feuerstein, GZ; Goldstein, RE; Laurindo, FR | 1 |
| McCulloch, RK; Rouse, IL; Summers, J; Vandongen, R | 1 |
| Kadowitz, PJ; Underwood, DC | 1 |
| Biffignandi, P; Cirillo, R; Franzone, JS | 1 |
| Bradley, LM; Feuerstein, G; Goldstein, RE | 1 |
| Blair, IA; Cragoe, EJ; Frazer, M; Limbird, LE; Reed, PW; Schwartzberg, MS; Sweatt, JD | 1 |
| Dillon, PK; Durán, WN; Ritter, AB | 1 |
| Daniel, EE; Jury, J; O'Byrne, P; Pashley, M; Serio, R | 1 |
| Daniel, EE; Serio, R | 1 |
| Iwama, T; Shikada, K; Tanaka, S | 1 |
| Badr, KF; DeBoer, DK; Fogo, A; Harris, RC; Jacobson, HR; Takahashi, K | 1 |
| Ambler, J; Birch, J; Maguire, ED; Wallis, RB | 1 |
| Bush, LR; Smith, SG | 1 |
| Robertson, DN; Smith, GM | 1 |
| Hallam, TJ; O'Connor, N; Rink, TJ; Simpson, AW | 1 |
| Friesen, LL; Gerrard, JM; Israels, SJ; McCrea, JM; Robinson, P | 1 |
| Bushfield, M; MacIntyre, DE; MacMillan, LJ; McNicol, A; Moffat, KJ; Murdoch, FA; Rossi, AG; Thomson, A | 1 |
| Feuerstein, G; Hallenbeck, JM | 1 |
| Piper, PJ; Stewart, AG | 1 |
| Lakin, KM | 1 |
| Altin, JG; Bygrave, FL | 1 |
| Myers, AK; Nakanishi, T; Ramwell, P | 1 |
| Cloutier, S; Jancar, S; Provençal, B; Sirois, P; Thériault, P | 1 |
| Del Monte, M; Subissi, A | 1 |
| Cassina, G; Livio, M; Macconi, D; Morelli, C; Morzenti, G; Remuzzi, G | 1 |
| Kito, M; Matsuura, T; Moriyama, T; Narita, H; Takamura, H; Tanaka, K | 1 |
| Kato, K; Nozawa, R; Sakurai, K; Suzuki, H; Suzuki, J; Suzuki, S | 1 |
| Berti, F; Bongrani, S; Magni, F; Pasargiklian, R; Rossoni, G; Schiantarelli, P | 1 |
| Katabami, F; Matsumiya, H; Matsuno, K | 1 |
| Böhm, R; Giessler, AJ | 1 |
| Homeister, JW; Jackson, CV; Lucchesi, BR; Mickelson, JK | 1 |
| Benveniste, J; Nunez, D; Russo-Marie, F | 1 |
| Czaja, JF; Ezra, D; Feuerstein, G; Goldstein, RE; Laurindo, FR; Snyder, F | 1 |
| Benveniste, J; Fouque, F; Joseph, D; Odiot, J; Vargaftig, BB | 1 |
| Ayer, DE; Gorman, RR; Miller, OV | 1 |
| Fouque, F; Lefort, J; Vargaftig, BB | 1 |
| Hechtman, HB; Shepro, D; Valeri, CR | 1 |
| Keenan, JP; Machin, SJ; McVerry, BA | 1 |
| Lefort, J; Rotilio, D; Vargaftig, BB | 1 |
| Sills, RH | 1 |
| Broekman, MJ; Kaplan, KL; Marcus, AJ; Safier, LB; Ullman, HL; Weksler, BB; Wong, KT | 1 |
| Goetzl, EJ; Valone, FH | 1 |
| Hamasaki, Y; Said, SI; Tai, HH | 1 |
| Benveniste, J; Chignard, M; Le Couedic, JP; Vargaftig, BB | 1 |
| Canham, EM; Heffner, JE; McMurtry, IF; Morris, HG; Patel, M; Repine, JE; Shoemaker, SA | 2 |
| Benveniste, J; Chignard, M; Lefort, J; Vargaftig, BB | 1 |
| Becker, K; Brodde, OE; Giessler, C; Heinroth-Hoffmann, I; Pönicke, K | 1 |
| Huang, YC; Nozik, ES; Piantadosi, CA | 1 |
| Arima, M; Fukuda, T; Makino, S; Yukawa, T | 1 |
| Enzan, K; Komatsu, H; Shoji, K; Suzuki, M | 1 |
| Arribas, I; Díez-Marques, ML; García-Escribano, MC; Pérez de Lema, G; Rodríguez-Puyol, D; Rodríguez-Puyol, M | 1 |
| Kirkpatrick, CJ; Klinge, U; Klosterhalfen, B; Mittermayer, C; Schumpelick, V; Töns, C | 1 |
| Kellie, S; Murphy, CT; Westwick, J | 1 |
| Hirafuji, M; Shinoda, H | 1 |
| Kase, N; Ohnishi, H; Tamura, N; Yamaura, T | 1 |
| Fujimura, M; Matsuda, T; Ogawa, H; Saito, M | 1 |
| Chern, JW; Chou, TC; Ding, YA; Yen, MH | 1 |
| Fletcher, JR; Khimenko, PL; Logsdon, P; Rizzo, A; Taylor, AE; Townsley, MI | 1 |
| Conger, JD; Falk, SA; Lanese, DM | 1 |
| Hidaka, T; Ishizuka, T; Kawaguchi, Y; Kawakami, M; Matsuki, Y; Nakamura, H; Suzuki, K | 1 |
| Evans, RJ; Hayes, LJ; Heath, MF; Littler, RM; McEvoy, RJ; Poole, AW | 1 |
| László, F; Moncada, S; Whittle, BJ | 1 |
| Chang, SW | 1 |
| Filep, JG; Földes-Filep, E; Fournier, A | 1 |
| Chiba, Y; Misawa, M | 1 |
| Hasegawa, S; Hirata, A; Hirata, F; Lee, JY; Nomura, A; Sakamoto, T; Uchida, Y | 1 |
| Hirata, Y; Nakano, M; Nakashima, M; Uematsu, T; Umemura, K | 1 |
| Iwama, T; Nagai, H; Sakurai, T; Yamaguchi, S | 1 |
| Alemany, M; Bastida, E; Bozzo, J; Hernández, R; Ordinas, A | 1 |
| Iizuka, Y; Itoh, K; Mukaiyama, O; Satoh, Y; Yamaguchi, T | 1 |
| Adachi, M; Horikoshi, S; Idaira, K; Imai, T; Sugeta, A; Takahashi, T; Tanaka, Y | 1 |
| Bugelski, PJ; Esser, KM; Feuerstein, G; Griswold, DE; Hillegass, LM; Rabinovici, R; Vernick, J | 1 |
| Barnes, PJ; Kato, M; Kuroume, T; Morikawa, A; Tokuyama, K | 1 |
| Akkerman, JW; Bruijnzeel, PL; Burgers, JA; Koenderman, L; Schweizer, RC | 1 |
| Hirata, Y; Matsuno, H; Nakashima, M; Takiguchi, Y; Uematsu, T; Umemura, K; Wada, K | 1 |
| Miura, K; Yamamoto, K; Yamanaka, S; Yukimura, T | 1 |
| Gabbeta, J; McLane, MA; Niewiarowski, S; Rao, AK; Sun, L; Yang, X | 1 |
| Evans, RJ; Jarvis, GE | 1 |
| Heptinstall, S; Lösche, W; Sanderson, HM; Vickers, J | 1 |
| Brasch, F; Featherstone, RL; Klein, T; Müller, KM; Nüsing, R; Uhlig, S; Ullrich, V; von Bethmann, A; Wendel, A | 1 |
| Ikeda, M; Kihara, T; Kogure, K; Matsuo, Y; Ninomiya, M; Onodera, H | 1 |
| Enzan, K; Inaba, H; Kurosawa, S; Yoshioka, N | 1 |
| Hidaka, T; Ishizuka, T; Kawakami, M; Matsuki, Y; Nakamura, H; Suzuki, K | 1 |
| Kamiya, S; Kanda, M; Kurahashi, K; Matsui, H; Nakamura, S; Shirahase, H; Wada, K | 1 |
| Martin, SL; Morse, DS; Stahl, GL | 1 |
| Gilani, AH; Majoo, RU; Saeed, SA; Shah, BH | 1 |
| Hu, DH; Ma, CT | 1 |
| Haruta, Y; Ishioka, S; Kambe, M; Moritani, C; Yamakido, M | 1 |
| Kannan, Y; Kimura, K; Moriyama, M; Musashi, M; Nishisako, M; Sakurada, K; Shiota, M; Sugano, T | 1 |
| Li, Y; Si, Y; Wang, F | 1 |
| Bache, RJ; Kinn, JW | 1 |
| Alonso, A; Bayón, Y; Hernández, M; Nieto, ML; Sánchez Crespo, M | 1 |
| Bocheński, J; Chłopicki, S; Gryglewski, RJ | 1 |
| Conroy, DM; Sirois, P | 1 |
| Chłopicki, S; Olszanecki, R | 1 |
| Quinn, JV; Slotman, GJ | 1 |
| Bartuś, JB; Chlopicki, S; Gryglewski, RJ | 1 |
| Anderson, GL; Guo, SZ; Miller, FN; Tsai, TM; Wang, WZ | 1 |
| Bardhan, KD; Brown, NJ; Jacob, S; Kalia, N; Reed, MW | 1 |
| Kubota, S; Mafune, N; Miyatake, T; Miyazaki, K; Murashita, T; Watanabe, S; Yasuda, K | 1 |
| Sakai, H; Suzuki, T; Takeguchi, N | 1 |
| Fukuoka, M; Haraguchi, R; Itoh, M; Kubo, H; Muraki, M; Nakajima, S; Tohda, Y | 1 |
| Kohno, S; Nabe, T | 1 |
| Hanif, S; Khan, FL; Rahman, HB; Rahman, IH; Rasheed, H; Saeed, SA; Shah, BH; Shariff, AH | 1 |
| Gresele, P; Mezzasoma, AM; Venditti, G; Vezza, R | 1 |
| Murota, M; Sakai, H; Suzuki, T; Takahashi, Y; Takeguchi, N | 1 |
| Abran, D; Almazan, G; Beauchamp, MH; Bernier, SG; Brault, S; Chemtob, S; Gobeil, F; Hou, X; Lachapelle, P; Marrache, AM; Peri, KG; Quiniou, C; Roberts, J; Varma, DR | 1 |
| Chlopicki, S; Gryglewski, RJ; Lomnicka, M | 1 |
| Koizumi, T; Kubo, K; Kurata, Y; Ogura, T; Ruan, Z; Shibamoto, T; Shimo, T; Tsuchida, H | 1 |
| Chap, H; Fourcade, O; Litt, L; Samii, K; Simon, MF | 1 |
| Rasheed, H; Saeed, SA | 1 |
| Bender, A; Gill, GS; Glen, RC; Mussa, HY | 1 |
| Beauchamp, M; Chemtob, S; Gobeil, F; Hardy, P; Lachapelle, P; Mwaikambo, B; Sennlaub, F; Tremblay, L | 1 |
| Chang, GT; Chang, YC; Chung, KH; Kang, SK; Kim, CH; Kim, JH | 1 |
| Engel, S; Göggel, R; Uhlig, S | 1 |
| Buchanan, MR | 1 |
| Cui, S; Kurata, Y; Liu, W; Shibamoto, T; Takano, H | 1 |
| Cloutier, S; Richter, M; Sirois, P | 1 |
| Gutbier, B; Ishii, S; Mayer, K; Mitchell, TJ; Owen, JS; Rosseau, S; Schmeck, B; Schütte, H; Suttorp, N; Thomas, MJ; Witzenrath, M | 1 |
| Bailey, SR; Cunningham, FM; Elliott, J; Menzies-Gow, NJ; Sepulveda, MF | 1 |
| Chemtob, S; Dorfman, AL; Hardy, P; Joly, S; Lachapelle, P | 1 |
| Caprani, A; Flaud, P; Guglielmi, JP; Richert, A | 1 |
| Guo, H; Li, B; Liu, LP; Shi, B; Yin, C | 1 |
| Boyce, JA; Laidlaw, TM | 1 |
| Dong, Z; Li, C; Liu, H; Liu, Y; Ren, J | 1 |
21 review(s) available for 1-hexadecyl-2-acetyl-glycero-3-phosphocholine and thromboxane a2
| Article | Year |
|---|---|
Bioactive mediators in asthma.
Topics: Asthma; Eicosanoic Acids; Humans; Immunity, Cellular; Leukotriene E4; Platelet Activating Factor; Prostaglandin-Endoperoxide Synthases; Prostaglandins; SRS-A; Thromboxane A2 | 1992 |
Phospholipids and their inhibitors: a critical evaluation of their role in the treatment of sepsis.
Topics: Animals; Cyclooxygenase Inhibitors; Humans; Leukotriene Antagonists; Phospholipids; Platelet Activating Factor; Prostaglandins, Synthetic; Sepsis; Shock, Septic; Thromboxane A2 | 1992 |
Cardiovascular effects of platelet-activating factor.
Topics: Animals; Cardiovascular Physiological Phenomena; Cardiovascular System; Hemodynamics; Platelet Activating Factor; Swine; Thromboxane A2 | 1991 |
[Relation of blood platelets and the cause of bronchial asthma].
Topics: Animals; Asthma; beta-Thromboglobulin; Blood Platelets; Humans; Platelet Activating Factor; Platelet Factor 4; Serotonin; Thromboxane A2 | 1989 |
Role of thromboxane A2.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Collagen; Epinephrine; Humans; Indomethacin; Kinetics; Platelet Activating Factor; Platelet Aggregation; Prostaglandin Endoperoxides; Prostaglandin Endoperoxides, Synthetic; Receptors, Prostaglandin; Receptors, Thromboxane; Serotonin; Thrombin; Thromboxane A2; Thromboxane B2 | 1985 |
Control and interrelation of aggregation and secretion; the roles of Ca2+, diacylglycerol and thromboxane with particular reference to ADP stimulation.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Blood Platelets; Calcium; Diglycerides; Epinephrine; Exocytosis; Glycerides; Humans; Platelet Activating Factor; Platelet Aggregation; Platelet Membrane Glycoproteins; Protein Kinase C; Receptors, Cell Surface; Receptors, Purinergic; Thrombin; Thromboxane A2 | 1985 |
Platelet protein phosphorylation.
Topics: Actin Cytoskeleton; Blood Platelets; Blood Proteins; Calcium; Carrier Proteins; Cyclic AMP; Cytoplasmic Granules; Cytoskeleton; Diglycerides; Gelsolin; Humans; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Lysophospholipids; Microfilament Proteins; Microtubules; Molecular Weight; Myosins; Phosphatidic Acids; Phosphoproteins; Phosphorylation; Platelet Activating Factor; Platelet Aggregation; Protein Kinase C; Tetradecanoylphorbol Acetate; Thromboxane A2 | 1985 |
Receptors and receptor mechanisms of endogenous platelet stimulatory and inhibitory mediators.
Topics: Adenosine; Adenosine Diphosphate; Blood Platelets; Epinephrine; Epoprostenol; Humans; Platelet Activating Factor; Platelet Aggregation; Prostaglandin D2; Prostaglandins D; Receptors, Cell Surface; Serotonin; Structure-Activity Relationship; Thrombin; Thromboxane A2; Vasopressins | 1986 |
Prostaglandins, leukotrienes, and platelet-activating factor in shock.
Topics: Animals; Fatty Acids, Unsaturated; Humans; Leukotriene B4; Platelet Activating Factor; Prostaglandins; Shock; SRS-A; Thromboxane A2 | 1987 |
[Problems of a pharmacologic search for inhibitors of platelet aggregation].
Topics: Drug Evaluation; Epoprostenol; Humans; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Stimulation, Chemical; Thromboxane A2 | 1988 |
[Thrombocyte aggregation inhibitors. A new class of active substances].
Topics: Adenylyl Cyclases; Animals; Anticoagulants; Blood Platelets; Cell Membrane; Eicosanoic Acids; Enzyme Activation; Epoprostenol; Humans; Phosphodiesterase Inhibitors; Platelet Activating Factor; Platelet Aggregation; Thromboxane A2 | 1986 |
Interaction of the formed elements of blood with the coronary vasculature in vivo.
Topics: Animals; Blood Cells; Coronary Disease; Coronary Thrombosis; Coronary Vessels; Dogs; Endothelium; Free Radicals; Leukocytes; Oxygen; Platelet Activating Factor; Platelet Aggregation; Rabbits; Thromboxane A2; Thromboxane-A Synthase; Vasoconstriction; Vasodilation; Xanthine Oxidase | 1987 |
[Platelet aggregation and PAF-acether. Pharmacologic interference].
Topics: Animals; Humans; Lipids; Platelet Activating Factor; Platelet Aggregation; Thromboxane A2 | 1984 |
Role of humoral mediators in adult respiratory distress syndrome.
Topics: Animals; Arachidonic Acids; Chemotaxis, Leukocyte; Chromones; Dogs; Guinea Pigs; Humans; Hypertension, Pulmonary; Inflammation; Ketanserin; Leukocyte Count; Leukocytes; Lung; Piperidines; Platelet Activating Factor; Pulmonary Embolism; Respiratory Distress Syndrome; Serotonin; Serotonin Antagonists; SRS-A; Thromboxane A2 | 1984 |
Thrombotic thrombocytopenic purpura. I. Pathophysiology and clinical manifestations.
Topics: Anemia, Hemolytic; Blood Coagulation Factors; Blood Platelets; Child; Diagnosis, Differential; Endothelium; Epoprostenol; Factor VIII; Female; Fever; Fibrinolytic Agents; Hemolytic-Uremic Syndrome; Humans; Kidney Diseases; Male; Neurologic Manifestations; Platelet Activating Factor; Purpura; Purpura, Thrombotic Thrombocytopenic; Thromboxane A2 | 1984 |
Mechanisms of cell signaling in immune-mediated inflammation.
Topics: Anaphylatoxins; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Chemokines; Chemotactic Factors; Dinoprostone; GTP-Binding Proteins; Immunoglobulin G; Inflammation; Leukocytes; Leukotriene B4; Leukotrienes; Lipids; Mice; Models, Biological; NF-kappa B; Phagocytes; Phospholipases A; Platelet Activating Factor; Signal Transduction; Thromboxane A2 | 1998 |
[Inflammatory mediators (leukotrienes, thromboxane A2, tachykinins and others)].
Topics: Arachidonic Acid; Asthma; Endothelins; Humans; Inflammation Mediators; Leukotriene Antagonists; Leukotrienes; Membrane Proteins; Platelet Activating Factor; Receptors, Leukotriene; Tachykinins; Thromboxane A2 | 2001 |
New insights into the retinal circulation: inflammatory lipid mediators in ischemic retinopathy.
Topics: Endothelial Cells; Humans; Ischemia; Lipid Peroxidation; Lipids; Oxidative Stress; Oxygen; Phospholipases A; Platelet Activating Factor; Prostaglandins; Reactive Oxygen Species; Regional Blood Flow; Retina; Retinal Diseases; Retinal Vessels; Signal Transduction; Thromboxane A2 | 2005 |
Mechanisms of platelet-activating factor (PAF)-mediated responses in the lung.
Topics: Animals; Ceramides; Dinoprostone; Endothelium, Vascular; Humans; Leukotrienes; Lung; Permeability; Platelet Activating Factor; Thromboxane A2 | 2005 |
The effect of oxygen and light on the structure and function of the neonatal rat retina.
Topics: Animals; Animals, Newborn; Disease Models, Animal; Fetal Development; Humans; Infant, Newborn; Isoprostanes; Light; Oxygen; Platelet Activating Factor; Rats; Retina; Retinitis Pigmentosa; Retinopathy of Prematurity; Thromboxane A2; Visual Pathways | 2009 |
Platelets in patients with aspirin-exacerbated respiratory disease.
Topics: Animals; Aspirin; Asthma, Aspirin-Induced; Blood Platelets; Bridged Bicyclo Compounds, Heterocyclic; Cell Movement; Clinical Trials as Topic; Eosinophils; Gene Expression; Humans; Leukotrienes; Oxazoles; Piperazines; Platelet Activating Factor; Platelet Activation; Prasugrel Hydrochloride; Receptors, Leukotriene; Thiophenes; Thromboxane A2 | 2015 |
1 trial(s) available for 1-hexadecyl-2-acetyl-glycero-3-phosphocholine and thromboxane a2
| Article | Year |
|---|---|
Role of thromboxane A2 as a mediator of platelet-activating-factor-induced aggregation of human platelets.
Topics: Adult; Aspirin; Collagen; Humans; Male; Platelet Activating Factor; Platelet Aggregation; Serotonin; Thromboxane A2; Thromboxane B2 | 1989 |
160 other study(ies) available for 1-hexadecyl-2-acetyl-glycero-3-phosphocholine and thromboxane a2
| Article | Year |
|---|---|
Interactions of prostanoids with the platelet activating factors.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Azepines; Guinea Pigs; Heart; Iloprost; In Vitro Techniques; Indomethacin; Myocardial Contraction; Perfusion; Platelet Activating Factor; Prostaglandins; Sulfonamides; Thromboxane A2; Thromboxane B2; Triazoles | 1992 |
Daltroban blocks thromboxane responses in the pulmonary vascular bed of the cat.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Arachidonic Acid; Blood Pressure; Cats; Endothelins; Female; Male; Phenylacetates; Platelet Activating Factor; Prostaglandin Endoperoxides, Synthetic; Pulmonary Circulation; Receptors, Prostaglandin; Receptors, Thromboxane; Serotonin; Sulfonamides; Thromboxane A2; Vasoconstrictor Agents | 1992 |
Activation of leukocytes with complement C5a is associated with prostanoid-dependent constriction of large arteries in atherosclerotic monkeys in vivo.
Topics: Animals; Arteries; Arteriosclerosis; Azepines; Bridged Bicyclo Compounds, Heterocyclic; Complement C5a; Fatty Acids, Unsaturated; Hemodynamics; Hydrazines; Leukocytes; Lipids; Macaca fascicularis; Male; Platelet Activating Factor; Prostaglandins; Thromboxane A2; Triazoles; Vasoconstriction | 1992 |
Platelet-activating factor as an intercellular signal in neutrophil-dependent platelet activation.
Topics: Amino Acid Sequence; Animals; Azepines; Blood Platelets; Cells, Cultured; Fibrinogen; Molecular Sequence Data; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oligopeptides; Platelet Activating Factor; Platelet Activation; Platelet Aggregation; Platelet Membrane Glycoproteins; Rabbits; Signal Transduction; Thromboxane A2; Triazoles | 1992 |
Defective platelet aggregation in response to platelet-activating factor in uremia associated with low platelet thromboxane A2 generation.
Topics: Adult; Aged; Blood Platelets; Female; Humans; Male; Middle Aged; Platelet Activating Factor; Platelet Aggregation; Protein Binding; Radioimmunoassay; Thromboxane A2; Thromboxane B2; Uremia | 1992 |
Putative mechanism of hypotensive action of platelet-activating factor in dogs.
Topics: Animals; Aspirin; Blood Pressure; Cardiac Output; Dogs; Female; Hemodynamics; Hypotension; Male; Platelet Activating Factor; Prostaglandins; Thromboxane A2; Time Factors; Vasodilation; Veins | 1992 |
Phosphorylation of the inhibitory guanine-nucleotide-binding protein as a possible mechanism of inhibition by protein kinase C of agonist-induced Ca2+ mobilization in human platelet.
Topics: Alkaloids; Amino Acid Sequence; Arginine Vasopressin; Blood Platelets; Blotting, Western; Calcium; Enzyme Activation; GTP-Binding Proteins; Humans; Molecular Sequence Data; Phosphorylation; Platelet Activating Factor; Precipitin Tests; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate; Thrombin; Thromboxane A2 | 1992 |
A potent inhibitor of platelet activating factor from the saliva of the leech Hirudo medicinalis.
Topics: Animals; Blood Platelets; Chemical Fractionation; Free Radicals; Hirudins; Humans; In Vitro Techniques; Leeches; Molecular Weight; Neutrophils; Platelet Activating Factor; Platelet Aggregation Inhibitors; Saliva; Thromboxane A2 | 1992 |
Tumor necrosis factor-alpha primes pulmonary hemodynamic response to N-formyl-L-methionyl-L-leucyl-L-phenylalanine.
Topics: Animals; Antioxidants; Drug Synergism; Guinea Pigs; Hemodynamics; Lung; N-Formylmethionine Leucyl-Phenylalanine; Organ Size; Peroxidase; Platelet Activating Factor; Pulmonary Circulation; Tetradecanoylphorbol Acetate; Thromboxane A2; Tumor Necrosis Factor-alpha; Vascular Resistance | 1991 |
Inhaled PAF stimulates leukotriene and thromboxane A2 production in humans.
Topics: Administration, Inhalation; Adult; Airway Resistance; Asthma; Bronchoconstrictor Agents; Eicosanoids; Endothelium, Vascular; Epoprostenol; Female; Humans; Leukotriene E4; Leukotrienes; Male; Methacholine Compounds; Platelet Activating Factor; Prostaglandins; SRS-A; Stimulation, Chemical; Thromboxane A2 | 1991 |
Receptor-mediated increase in cytosolic calcium in LLC-PK1 cells by platelet activating factor and thromboxane A2.
Topics: Animals; Azepines; Calcium; Carbazoles; Cell Line; Cytosol; Kidney Tubules, Proximal; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Receptors, Prostaglandin; Receptors, Thromboxane; Tetrazoles; Thienopyridines; Thromboxane A2; Triazoles | 1991 |
Synergistic effect of thromboxane A2 and N-formylmethionylleucylphenylalanine on platelet-activating factor synthesis in human polymorphonuclear neutrophils.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetyl-CoA C-Acetyltransferase; Binding Sites; Bridged Bicyclo Compounds; Drug Synergism; Fatty Acids, Monounsaturated; Humans; Kinetics; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Prostaglandin Endoperoxides, Synthetic; Receptors, Prostaglandin; Thromboxane A2 | 1991 |
Prostaglandin endoperoxide/thromboxane A2 receptor desensitization. Cross-talk with adenylate cyclase in human platelets.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenylyl Cyclases; Cyclic AMP; Down-Regulation; Enzyme Activation; Humans; Iloprost; In Vitro Techniques; Platelet Activating Factor; Platelet Activation; Platelet Aggregation; Prostaglandin Endoperoxides; Prostaglandin Endoperoxides, Synthetic; Protein Kinase C; Receptors, Prostaglandin; Receptors, Thromboxane; Thrombin; Thromboxane A2; Type C Phospholipases | 1990 |
In vivo enhancement of platelet activating factor-induced prostacyclin production by OKY-046, a selective inhibitor of thromboxane A2 synthase.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Blood Pressure; Dose-Response Relationship, Drug; Epoprostenol; Female; Heart Rate; Hemodynamics; Male; Methacrylates; Platelet Activating Factor; Swine; Thromboxane A2; Thromboxane-A Synthase; Vascular Resistance | 1991 |
[The interaction of platelet and vascular endothelial cell].
Topics: Angiogenesis Inducing Agents; Arachidonic Acid; Blood Coagulation Factors; Blood Platelets; Cell Communication; Cell Division; Endothelins; Endothelium, Vascular; Epoprostenol; Heparan Sulfate Proteoglycans; Heparitin Sulfate; Humans; Nitric Oxide; Platelet Activating Factor; Platelet Aggregation; Proteoglycans; Thromboxane A2 | 1991 |
Mechanisms of thrombocytopenia in the acute phase of antigen-induced arthritis in rabbits.
Topics: Animals; Arthritis, Experimental; Diterpenes; Econazole; Female; Ginkgolides; Indoles; Indomethacin; Lactones; Male; Platelet Activating Factor; Rabbits; Synovial Fluid; Thrombocytopenia; Thromboxane A2; Thromboxane B2 | 1991 |
Nephrotoxicity of cyclosporine: the role of platelet-activating factor and thromboxane.
Topics: Animals; Blood Pressure; Cyclosporine; Glomerular Filtration Rate; Imidazoles; Kidney; Male; Platelet Activating Factor; Rats; Rats, Inbred Strains; Reference Values; Renal Circulation; Thromboxane A2; Thromboxane-A Synthase | 1991 |
Role of thromboxane A2 in airway microvascular leakage induced by inhaled platelet-activating factor.
Topics: Administration, Inhalation; Airway Resistance; Animals; Blood Pressure; Capillary Permeability; Dioxanes; Female; Guinea Pigs; Histamine; Methacrylates; Microcirculation; Platelet Activating Factor; Receptors, Prostaglandin; Receptors, Thromboxane; Respiratory System; Thromboxane A2; Thromboxane-A Synthase | 1991 |
Contribution of platelets and platelet-activating factor (PAF) to the arrhythmogenic, haemodynamic and necrotic effects of acute myocardial ischaemia.
Topics: Animals; Arrhythmias, Cardiac; Blood Platelets; Diterpenes; Ginkgolides; Hypotension; Imidazoles; Immune Sera; Lactones; Myocardial Infarction; Necrosis; Platelet Activating Factor; Platelet Activation; Pyridines; Rabbits; Thromboxane A2; Thromboxane-A Synthase | 1991 |
Role of platelet-activating factor in renal function in normal rats and rats with bilateral ureteral obstruction.
Topics: Animals; Female; Furans; Glomerular Filtration Rate; Kidney; Methacrylates; Platelet Activating Factor; Radioimmunoassay; Rats; Rats, Inbred Strains; Renal Circulation; Thromboxane A2; Thromboxane-A Synthase; Ureteral Obstruction | 1991 |
Influence of SK&F 96148 on thromboxane-mediated responses in the airways of the cat.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Airway Resistance; Animals; Arachidonic Acid; Arachidonic Acids; Cats; Endothelins; Endotoxins; Escherichia coli; Female; Male; Phenylacetates; Platelet Activating Factor; Prostaglandin Endoperoxides, Synthetic; Respiratory Physiological Phenomena; Respiratory System; Sulfonamides; Thromboxane A2; Thromboxanes | 1991 |
[The role of thromboxane A2 in the development of airway responsiveness after platelet activating factor inhalation in dogs].
Topics: Administration, Inhalation; Airway Resistance; Animals; Benzoquinones; Bronchi; Bronchoalveolar Lavage Fluid; Dogs; Female; Heptanoic Acids; Leukocyte Count; Methacholine Chloride; Platelet Activating Factor; Quinones; Thromboxane A2 | 1991 |
Selective implication of thromboxane A2 and PAF-acether in two guinea pig anaphylactic models.
Topics: Anaphylaxis; Animals; Antigens; Glyceryl Ethers; Guinea Pigs; Immunoglobulin E; Immunoglobulin G; In Vitro Techniques; Indomethacin; Muscle Contraction; Platelet Activating Factor; Thiazoles; Thromboxane A2; Trachea | 1990 |
Mechanisms of platelet activating factor-induced aggregation and secretion in human platelets.
Topics: Adult; Blood Platelets; Calcimycin; Calcium; Collagen; Humans; Kinetics; Male; Middle Aged; Platelet Activating Factor; Platelet Aggregation; Serotonin; Thromboxane A2 | 1990 |
The correlation between Ca2+ influx and inositol 1, 4, 5-trisphosphate (IP3) formation in platelets stimulated by various agonists.
Topics: Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Calcium; Humans; Inositol 1,4,5-Trisphosphate; Ionomycin; Platelet Activating Factor; Temperature; Thrombin; Thromboxane A2 | 1990 |
Inhibition of cyclooxygenase-independent platelet aggregation by low vitamin E concentration.
Topics: alpha-Tocopherol; Apyrase; Aspirin; Blood Platelets; Collagen; Epinephrine; Humans; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Prostaglandin-Endoperoxide Synthases; Thromboxane A2; Tocopherols; Vitamin E | 1990 |
Acute microcirculatory effects of platelet-activating factor.
Topics: Animals; Capillary Permeability; Cell Adhesion; Cricetinae; Endothelium, Vascular; Leukocytes; Microcirculation; Platelet Activating Factor; Thromboxane A2; Vasoconstriction | 1990 |
Involvement of platelet activating factor and thromboxane A2 in the renal response to unilateral ureteral obstruction.
Topics: Animals; Blood Pressure; Bridged Bicyclo Compounds, Heterocyclic; Dogs; Fatty Acids, Unsaturated; Female; Hydrazines; Platelet Activating Factor; Pressure; Prostaglandin Endoperoxides, Synthetic; Quinolinium Compounds; Receptors, Prostaglandin; Receptors, Thromboxane; Renal Circulation; Thromboxane A2; Ureter; Ureteral Obstruction; Vascular Resistance; Vasoconstriction | 1990 |
Effects of platelet activating factor antagonists on arachidonic acid-induced platelet aggregation and TXA2 formation.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Azepines; Blood Platelets; Diterpenes; Ginkgolides; Imidazoles; In Vitro Techniques; Lactones; Naphthalenes; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Rabbits; Receptors, Prostaglandin; Receptors, Thromboxane; Sulfonamides; Thromboxane A2; Thromboxane-A Synthase; Triazoles | 1990 |
Inhibition of rabbit platelet aggregation by 1,4-naphthoquinones.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Calcimycin; Calcium; Collagen; Naphthoquinones; Phosphatidylinositols; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Rabbits; Thrombin; Thromboxane A2 | 1990 |
Platelet activating factor stimulates cyclo-oxygenase activity in guinea pig eosinophils. Concerted biosynthesis of thromboxane A2 and E-series prostaglandins.
Topics: Animals; Azepines; Calcimycin; Calcium; Complement C5a; Cyclooxygenase Inhibitors; Enzyme Activation; Eosinophils; Flurbiprofen; Guinea Pigs; Imidazoles; In Vitro Techniques; N-Formylmethionine Leucyl-Phenylalanine; Platelet Activating Factor; Platelet Membrane Glycoproteins; Prostaglandin-Endoperoxide Synthases; Prostaglandins E; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Superoxides; Tetradecanoylphorbol Acetate; Thromboxane A2; Thromboxane B2; Thromboxane-A Synthase; Triazines; Triazoles | 1990 |
Inhibitory action of OKY-O46.HCl, a specific TXA2 synthetase inhibitor, on platelet activating factor (PAF)-induced airway hyperresponsiveness of guinea pigs: role of TXA2 in development of PAF-induced nonspecific airway hyperresponsiveness.
Topics: Acrylates; Animals; Atropine; Autonomic Nervous System; Calcium Radioisotopes; Guinea Pigs; Hemicholinium 3; Hexamethonium Compounds; Kinetics; Male; Methacrylates; Platelet Activating Factor; Receptors, Adrenergic, beta; Receptors, Muscarinic; Respiratory System; Thromboxane A2; Thromboxane-A Synthase | 1990 |
[Enzyme inhibitors and receptor antagonists in the arachidonic cascade].
Topics: Anti-Inflammatory Agents; Arachidonic Acids; Cyclooxygenase Inhibitors; Enzyme Inhibitors; Humans; Leukotriene B4; Lipoxygenase Inhibitors; Phospholipases; Platelet Activating Factor; Thromboxane A2; Thromboxane-A Synthase | 1990 |
Distinct stimulatory effect of platelet-activating factor on prostaglandin I2 and thromboxane A2 biosynthesis by rat dental pulp.
Topics: Animals; Calcimycin; Calcium; Dental Pulp; Epoprostenol; In Vitro Techniques; Kinetics; Male; Platelet Activating Factor; Rats; Rats, Inbred Strains; Stimulation, Chemical; Thromboxane A2 | 1990 |
Endothelin-1 and platelet activating factor stimulate thromboxane A2 biosynthesis in rat vascular smooth muscle cells.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Calcium; Cells, Cultured; Dexamethasone; Endothelins; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Rats; Rats, Inbred Strains; Thromboxane A2; Thromboxane B2 | 1990 |
[Inhibitory effects of OKY-046.HCl, a selective thromboxane (TX) A2 synthetase inhibitor, on platelet activating factor (PAF)-induced airway hyperresponsiveness in guinea pigs].
Topics: Acrylates; Animals; Asthma; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Guinea Pigs; In Vitro Techniques; Male; Methacrylates; Platelet Activating Factor; Thromboxane A2; Thromboxane-A Synthase | 1990 |
Effect of thromboxane A2 synthetase inhibition, singly and combined with thromboxane A2/prostaglandin endoperoxide receptor antagonism, on inositol phospholipid turnover and on 5-HT release by washed human platelets.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Blood Platelets; Collagen; Humans; In Vitro Techniques; Indomethacin; Inositol Phosphates; Methacrylates; Platelet Activating Factor; Prostaglandin Endoperoxides; Prostaglandin Endoperoxides, Synthetic; Serotonin; Sulfonamides; Thromboxane A2; Thromboxane-A Synthase | 1990 |
Predominant functional roles for thromboxane A2 and prostaglandin E2 during late nephrotoxic serum glomerulonephritis in the rat.
Topics: Animals; Blood Pressure; Dinoprost; Dinoprostone; Glomerular Filtration Rate; Glomerulonephritis; Hematocrit; Male; Platelet Activating Factor; Proteinuria; Rats; Thromboxane A2; Vascular Resistance | 1990 |
Receptor-operated channels in human platelets.
Topics: Adenosine Diphosphate; Barium; Biological Transport; Blood Platelets; Cadmium; Calcium; Cesium; Electrophoresis, Gel, Two-Dimensional; Humans; Ion Channels; Lithium; Membrane Potentials; Nickel; Platelet Activating Factor; Sodium; Spectrometry, Fluorescence; Thrombin; Thromboxane A2 | 1989 |
Reversal of A23187-induced airway constriction in the guinea pig.
Topics: Airway Obstruction; Airway Resistance; Albuterol; Animals; Calcimycin; Dose-Response Relationship, Drug; Ergolines; Guinea Pigs; Leukotrienes; Lung Compliance; Male; Platelet Activating Factor; Serotonin; Thromboxane A2 | 1989 |
Lipid inflammatory mediators in glomerulonephritis.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Glomerulonephritis; Humans; Platelet Activating Factor; Thromboxane A2 | 1989 |
Relationship between PAF-acether and thromboxane A2 biosynthesis in endotoxin-induced intestinal damage in the rat.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Escherichia coli; Ethanol; Imidazoles; Indomethacin; Jejunum; Lipopolysaccharides; Male; Methacrylates; Platelet Activating Factor; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Rats; Rats, Inbred Strains; Shock, Septic; Thromboxane A2; Thromboxane-A Synthase | 1989 |
Inhibition of cyclooxygenase-independent platelet aggregation by sodium salicylate.
Topics: Adult; Aspirin; Epinephrine; Female; Humans; Male; Platelet Activating Factor; Platelet Aggregation Inhibitors; Prostaglandin-Endoperoxide Synthases; Sodium Salicylate; Thromboxane A2 | 1989 |
Interactions of platelet activating factor, thromboxane A2 and leukotrienes in guinea-pig heart.
Topics: Anaphylaxis; Animals; Azepines; Cyclooxygenase Inhibitors; Guinea Pigs; Heart; In Vitro Techniques; Indomethacin; Leukotrienes; Lipoxygenase Inhibitors; Naphthoquinones; ortho-Aminobenzoates; Platelet Activating Factor; Thromboxane A2; Triazines; Triazoles | 1989 |
Enhanced glomerular thromboxane A2 mediates some pathophysiologic effect of platelet-activating factor in rabbit nephrotoxic nephritis: evidence from biochemical measurements and inhibitor trials.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Furans; Glomerulonephritis; Kidney; Kidney Glomerulus; Male; Platelet Activating Factor; Platelet Aggregation; Platelet Membrane Glycoproteins; Prostaglandins; Rabbits; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Thromboxane A2; Thromboxane-A Synthase | 1989 |
Equine peritoneal macrophage production of thromboxane and prostacyclin in response to platelet activating factor and its receptor antagonist SRI 63-441.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Calcimycin; Endotoxins; Epoprostenol; Escherichia coli; Female; Horses; Macrophages; Male; Peritoneal Cavity; Platelet Activating Factor; Platelet Membrane Glycoproteins; Quinolinium Compounds; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Thromboxane A2; Thromboxane B2 | 1989 |
Evidence for two mechanisms of thrombin-induced platelet activation: one proteolytic, one receptor mediated.
Topics: Adenosine Diphosphate; Humans; In Vitro Techniques; Leupeptins; Phosphatidylinositols; Platelet Activating Factor; Platelet Activation; Receptors, Cell Surface; Receptors, Thrombin; Serotonin; Thrombin; Thromboxane A2; Trypsin | 1989 |
Effects of ethanol on human platelets stimulated with platelet-activating factor, a biologically active ether phospholipid.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Aspirin; Blood Platelets; Ethanol; Humans; In Vitro Techniques; Platelet Activating Factor; Platelet Aggregation; Platelet Membrane Glycoproteins; Prostaglandin Endoperoxides, Synthetic; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Receptors, Prostaglandin; Receptors, Thromboxane; Serotonin; Thromboxane A2 | 1989 |
Characterization of the normal bovine platelet aggregation response.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acids; Cattle; Epinephrine; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Radioimmunoassay; Serotonin; Thrombin; Thromboxane A2; Thromboxane B2 | 1989 |
Influence of thromboxane A2 receptor antagonism on pulmonary vasoconstrictor responses.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Animals, Newborn; Blood Pressure; Bridged Bicyclo Compounds, Heterocyclic; Fatty Acids, Unsaturated; Female; Hemodynamics; Hydrazines; Hypoxia; Lung; Male; Platelet Activating Factor; Prostaglandin Endoperoxides, Synthetic; Swine; Thromboxane A2; Vasoconstriction | 1989 |
Endothelin-induced mobilization of Ca2+ and the possible involvement of platelet activating factor and thromboxane A2.
Topics: Animals; Benzofurans; Calcium; Cells, Cultured; Endothelins; Endothelium, Vascular; Fluorescent Dyes; Fura-2; Male; Muscle, Smooth, Vascular; Peptides; Platelet Activating Factor; Pyridinium Compounds; Rabbits; Rats; Rats, Inbred Strains; Thromboxane A2 | 1989 |
Platelet-activating factor increases platelet-dependent glycoconjugate secretion from tracheal submucosal gland.
Topics: Animals; Blood Platelets; Bridged Bicyclo Compounds, Heterocyclic; Cats; Fatty Acids, Unsaturated; Glucosamine; Glycoconjugates; Hydrazines; In Vitro Techniques; Indomethacin; Kinetics; Methysergide; Mucous Membrane; Phospholipid Ethers; Platelet Activating Factor; Radioisotope Dilution Technique; Thromboxane A2; Trachea; Tritium | 1989 |
Mechanisms of hypotension produced by platelet-activating factor.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Female; Hypotension; Indomethacin; Male; Methacrylates; Platelet Activating Factor; Prostaglandin Endoperoxides, Synthetic; Swine; Thromboxane A2; Thromboxane-A Synthase | 1989 |
Analysis of bronchoconstrictor responses to platelet-activating factor in the cat.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Airway Resistance; Animals; Blood Pressure; Bridged Bicyclo Compounds, Heterocyclic; Bronchi; Cats; Fatty Acids, Unsaturated; Female; Hydrazines; Lung Compliance; Male; Meclofenamic Acid; Phospholipid Ethers; Platelet Activating Factor; Prostaglandin Endoperoxides, Synthetic; Thromboxane A2 | 1989 |
Doxofylline exerts a prophylactic effect against bronchoconstriction and pleurisy induced by PAF.
Topics: Airway Resistance; Anesthesia; Animals; Binding, Competitive; Bronchi; Bronchodilator Agents; Female; Guinea Pigs; In Vitro Techniques; Injections; Injections, Intravenous; Lung; Male; Muscle Contraction; Platelet Activating Factor; Pleurisy; Theophylline; Thromboxane A2 | 1989 |
The role of lipid mediators in hypoxic pulmonary vasoconstriction in newborns.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetophenones; Animals; Animals, Newborn; Bridged Bicyclo Compounds, Heterocyclic; Fatty Acids, Unsaturated; Hydrazines; Hypoxia; Lipids; Platelet Activating Factor; Prostaglandin Endoperoxides, Synthetic; Pulmonary Circulation; SRS-A; Swine; Tetrazoles; Thromboxane A2; Vasoconstriction | 1989 |
Evidence for a role for Na+-H+ exchange in activation of human platelets by PAF.
Topics: Amiloride; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Bridged Bicyclo Compounds, Heterocyclic; Fatty Acids, Unsaturated; Humans; Hydrazines; Indomethacin; Platelet Activating Factor; Platelet Aggregation; Protons; Serotonin; Sodium; Thromboxane A2; Thromboxane B2 | 1987 |
Vasoconstrictor effects of platelet-activating factor in the hamster cheek pouch microcirculation: dose-related relations and pathways of action.
Topics: Animals; Arterioles; Benzofurans; Blood Pressure; Cheek; Cricetinae; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Hematocrit; Lignans; Male; Mesocricetus; Microcirculation; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Thromboxane A2; Vasoconstriction | 1988 |
Effects of inflammatory mediators on neuromuscular transmission in canine trachea in vitro.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Bronchial Spasm; Dogs; In Vitro Techniques; Leukotriene B4; Muscle, Smooth; Ozone; Platelet Activating Factor; Prostaglandin Endoperoxides, Synthetic; SRS-A; Synaptic Transmission; Thromboxane A2; Trachea | 1988 |
Thromboxane effects on canine trachealis neuromuscular function.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Bridged Bicyclo Compounds, Heterocyclic; Dogs; Fatty Acids, Unsaturated; Female; Hydrazines; In Vitro Techniques; Leukotriene B4; Male; Muscle, Smooth; Neuromuscular Junction; Platelet Activating Factor; Prostaglandin D2; Prostaglandin Endoperoxides, Synthetic; Prostaglandins D; SRS-A; Thromboxane A2; Trachea | 1988 |
Pharmacological modulation of platelet activating factor (PAF)-induced bronchoconstriction and hypertension in anaesthetized guinea-pigs.
Topics: Animals; Blood Pressure; Bronchial Spasm; Cyclooxygenase Inhibitors; Guinea Pigs; Hypertension; In Vitro Techniques; Leukotriene Antagonists; Leukotrienes; Lipoxygenase; Lipoxygenase Inhibitors; Male; Platelet Activating Factor; Prostaglandin-Endoperoxide Synthases; Thromboxane A2 | 1988 |
Glomerular responses to platelet-activating factor in the rat: role of thromboxane A2.
Topics: Animals; Blood Pressure; Dinoprostone; Glomerular Filtration Rate; Hemodynamics; Kidney Glomerulus; Male; Platelet Activating Factor; Rats; Thromboxane A2; Ultrafiltration | 1989 |
Antagonism of U46619-induced aggregation of human and canine platelets by four TXA2 receptor antagonists.
Topics: Adenosine Diphosphate; Animals; Dogs; Epinephrine; Humans; In Vitro Techniques; Indomethacin; Platelet Activating Factor; Platelet Aggregation; Prostaglandin Endoperoxides, Synthetic; Receptors, Prostaglandin; Receptors, Thromboxane; Thromboxane A2 | 1986 |
Role of thromboxane A2, 5-hydroxytryptamine, and platelet activating factor in collagen-induced sudden death in rabbits.
Topics: Animals; Blood Platelets; Collagen; Death, Sudden; Disease Models, Animal; Male; Platelet Activating Factor; Rabbits; Serotonin; Thromboxane A2 | 1987 |
Antagonism of vasoconstriction induced by platelet-activating factor in guinea-pig perfused hearts by selective platelet-activating factor receptor antagonists.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Chromones; Coronary Vessels; Diterpenes; Furans; Ginkgolides; Guinea Pigs; In Vitro Techniques; Indomethacin; Lactones; Leukotriene B4; Male; Perfusion; Plant Extracts; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; SRS-A; Thromboxane A2; Time Factors; Vasoconstriction | 1987 |
Prostaglandin F2 alpha and the thromboxane A2 analogue ONO-11113 stimulate Ca2+ fluxes and other physiological responses in rat liver. Further evidence that prostanoids may be involved in the action of arachidonic acid and platelet-activating factor.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Calcium; Dinoprost; Dinoprostone; Glucagon; In Vitro Techniques; Liver; Male; Oxygen Consumption; Phenylephrine; Platelet Activating Factor; Prostaglandin D2; Prostaglandins D; Prostaglandins E; Prostaglandins F; Rats; Rats, Inbred Strains; Thromboxane A2; Vasoconstriction | 1988 |
Antagonism of PAF-induced death in mice.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Arachidonic Acid; Arachidonic Acids; Bridged Bicyclo Compounds, Heterocyclic; Collagen; Diterpenes; Epinephrine; Fatty Acids, Unsaturated; Furans; Ginkgolides; Hydrazines; Lactones; Male; Mice; Platelet Activating Factor; Platelet Aggregation Inhibitors; Prostaglandin Endoperoxides, Synthetic; Pyridines; Thiazoles; Thromboxane A2 | 1988 |
Mechanism of action of platelet-activating factor on guinea-pig lung parenchyma strips.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Guinea Pigs; Immunoenzyme Techniques; Lung; Masoprocol; Methacrylates; Muscle Contraction; Platelet Activating Factor; Pyrazoles; Sulfonamides; Thromboxane A2; Thromboxane B2 | 1988 |
Platelet-activating factor-induced contraction of guinea-pig lung parenchymal strips: possible involvement of arachidonate metabolites.
Topics: Acetylcholine; Animals; Arachidonic Acids; Atropine; Azepines; Cyclooxygenase Inhibitors; Guinea Pigs; Hypnotics and Sedatives; In Vitro Techniques; Lipoxygenase Inhibitors; Lung; Male; Muscle Contraction; Muscle, Smooth; Platelet Activating Factor; Thromboxane A2; Triazines; Triazoles | 1988 |
Acetyl glycerylphosphorylcholine aggregates human platelets through two distinct pathways, both dependent on arachidonic acid metabolism.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Arachidonic Acid; Arachidonic Acids; Aspirin; Blood Platelets; Catechols; Chromatography, Thin Layer; Cyclooxygenase Inhibitors; Humans; Imidazoles; In Vitro Techniques; Lipoxygenase Inhibitors; Masoprocol; Phospholipases; Platelet Activating Factor; Platelet Aggregation; Prostanoic Acids; Quinacrine; Radioimmunoassay; Receptors, Prostaglandin; Receptors, Thromboxane; Thromboxane A2; Thromboxane-A Synthase | 1985 |
Elevation of cytosolic free Ca2+ is directly evoked by thromboxane A2 in human platelets during activation with collagen.
Topics: Blood Platelets; Calcium; Collagen; Cytosol; Enzyme Activation; Humans; In Vitro Techniques; Platelet Activating Factor; Thromboxane A2; Type C Phospholipases | 1988 |
[Effect of a specific antagonist of platelet-activating factor, FR-900452, on proteinuria and urinary thromboxane excretion in aminonucleoside nephrotic rats].
Topics: Animals; Indoles; Male; Nephrotic Syndrome; Piperazines; Platelet Activating Factor; Proteinuria; Puromycin Aminonucleoside; Rats; Rats, Inbred Strains; Thromboxane A2 | 1988 |
New pharmacological data on the bronchospasmolytic activity of bamifylline.
Topics: Acetylcholine; Airway Resistance; Anaphylaxis; Animals; Bronchodilator Agents; Guinea Pigs; Histamine; Male; Platelet Activating Factor; SRS-A; Theophylline; Thromboxane A2 | 1988 |
[Cytoplasm free calcium ions as a second messenger].
Topics: Aequorin; Aminoquinolines; Blood Platelets; Calcium; Humans; Ions; Platelet Activating Factor; Platelet Aggregation; Spectrometry, Fluorescence; Tetradecanoylphorbol Acetate; Thrombin; Thromboxane A2 | 1987 |
[Effects of SIN-1, a metabolite of molsidomine, on paf-acether-blood platelets interactions].
Topics: Animals; Blood Platelets; Molsidomine; Platelet Activating Factor; Platelet Aggregation; Rabbits; Thromboxane A2 | 1987 |
Cardiac and coronary consequences of intracoronary platelet activating factor infusion in the domestic pig.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Coronary Circulation; Coronary Vessels; Female; Heart; Indomethacin; Infusions, Intra-Arterial; Male; Nitroprusside; Platelet Activating Factor; SRS-A; Swine; Thromboxane A2 | 1987 |
Synergized activation of human platelets by epinephrine and platelet-activating factor-acether is adenosine diphosphate and thromboxane A2-independent.
Topics: Adenosine Diphosphate; Drug Synergism; Epinephrine; Humans; Kinetics; Platelet Activating Factor; Platelet Aggregation; Thromboxane A2; Thromboxanes | 1983 |
Acetyl glycerylphosphorylcholine inhibition of prostaglandin I2-stimulated adenosine 3',5'-cyclic monophosphate levels in human platelets. Evidence for thromboxane A2 dependence.
Topics: Blood Platelets; Cyclic AMP; Dose-Response Relationship, Drug; Epoprostenol; Humans; Indomethacin; Lysophosphatidylcholines; Platelet Activating Factor; Platelet Aggregation; Prostaglandins; Thromboxane A2; Thromboxane B2; Thromboxane-A Synthase; Thromboxanes | 1982 |
Defective platelet aggregation to the calcium ionophore A23187 in a patient with a lifelong bleeding disorder.
Topics: Arachidonic Acids; Bleeding Time; Blood Platelet Disorders; Calcimycin; Calcium; Female; Humans; Middle Aged; Nucleotides; Platelet Activating Factor; Platelet Aggregation; Thromboxane A2 | 1983 |
The platelet-independent release of thromboxane A2 by Paf-acether from guinea-pig lungs involves mechanisms distinct from those for leukotriene.
Topics: Aerosols; Animals; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Bradykinin; Female; In Vitro Techniques; Lung; Male; Mice; Muscle Contraction; Muscle, Smooth; Perfusion; Platelet Activating Factor; SRS-A; Thromboxane A2; Thromboxanes | 1984 |
Effects of acetyl glyceryl ether phosphorylcholine on human platelet function in vitro.
Topics: Adenosine Diphosphate; Apyrase; beta-Thromboglobulin; Blood Platelets; Calcium; Creatine Kinase; Drug Synergism; Humans; Lysophosphatidylcholines; Phosphocreatine; Platelet Activating Factor; Platelet Aggregation; Platelet Factor 4; Serotonin; Thromboxane A2 | 1981 |
Enhancement of human polymorphonuclear leukocyte adherence by the phospholipid mediator 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphorylcholine (AGEPC).
Topics: Adult; Cell Adhesion; Dose-Response Relationship, Drug; Humans; Indomethacin; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Thromboxane A2 | 1983 |
[Effects of platelet activating factor (PAF:AGEPC) on airway and pulmonary vascular constriction of guinea pigs--with special reference to the relation with TXA2].
Topics: Airway Resistance; Animals; Female; Guinea Pigs; Platelet Activating Factor; Pulmonary Artery; Thromboxane A2; Thromboxanes; Vasoconstriction | 1983 |
One, two, three or more pathways for platelet aggregation.
Topics: Acetophenones; Adenosine Diphosphate; Arachidonic Acids; Aspirin; Blood Platelets; Cyclooxygenase Inhibitors; Humans; Lysophosphatidylcholines; Platelet Activating Factor; Platelet Aggregation; Prostaglandin-Endoperoxide Synthases; Thrombin; Thromboxane A2 | 1980 |
Acetyl glyceryl ether phosphorylcholine-stimulated human platelets cause pulmonary hypertension and edema in isolated rabbit lungs. Role of thromboxane A2.
Topics: Animals; Blood Platelets; Female; Hypertension, Pulmonary; Imidazoles; Lung; Male; Perfusion; Platelet Activating Factor; Pressure; Prostanoic Acids; Pulmonary Edema; Rabbits; Thromboxane A2 | 1983 |
Platelet-induced pulmonary hypertension and edema. A mechanism involving acetyl glyceryl ether phosphorylcholine and thromboxane A2.
Topics: Albumins; Animals; Blood Platelets; Hypertension, Pulmonary; Lung; Neutrophils; Platelet Activating Factor; Pulmonary Edema; Rabbits; Thromboxane A2; Thromboxanes | 1983 |
Platelet-activating factor induces a platelet-dependent bronchoconstriction unrelated to the formation of prostaglandin derivatives.
Topics: Animals; Aspirin; Blood Platelets; Bronchial Spasm; Epoprostenol; In Vitro Techniques; Lysophosphatidylcholines; Platelet Activating Factor; Platelet Aggregation; Prostaglandins; Rabbits; Thromboxane A2; Time Factors | 1980 |
PAF effects on eicosanoid release in neonatal rat cardiomyocytes.
Topics: Animals; Animals, Newborn; Aspirin; Azepines; Cyclooxygenase Inhibitors; Epoprostenol; Heart; Platelet Activating Factor; Platelet Aggregation Inhibitors; Rats; Rats, Wistar; Thromboxane A2; Triazoles | 1995 |
Superoxide dismutase potentiates platelet-activating factor-induced injury in perfused lung.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Amino Acid Oxidoreductases; Animals; Catalase; Ditiocarb; Epoprostenol; In Vitro Techniques; Lung; Male; Nitric Oxide Synthase; Perfusion; Platelet Activating Factor; Rabbits; Superoxide Dismutase; Thromboxane A2 | 1994 |
[Effect of BAY u3405-thromboxane A2 receptor antagonist, on biphasic airway responses induced by platelet-activating factor in actively sensitized guinea pigs].
Topics: Airway Resistance; Animals; Carbazoles; Guinea Pigs; Male; Platelet Activating Factor; Platelet Aggregation Inhibitors; Receptors, Thromboxane; Sulfonamides; Thromboxane A2; Vaccination | 1995 |
[Effects of thromboxane on pulmonary arterial response to platelet activating factor in rabbit].
Topics: Airway Resistance; Animals; Hemodynamics; Platelet Activating Factor; Pulmonary Artery; Rabbits; Thromboxane A2 | 1995 |
Thromboxane A2 and platelet-activating factor decrease in the platelet-mesangial cell interactions.
Topics: Animals; Blood Platelets; Cell Communication; Cells, Cultured; Glomerular Mesangium; Platelet Activating Factor; Rats; Rats, Wistar; Thromboxane A2; Thromboxane B2 | 1995 |
[Septic shock and multiple organ failure in surgical intensive care. An animal experiment model on the analysis of pulmonary and intestinal dysfunction].
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Critical Care; Epoprostenol; Escherichia coli Infections; Hemodynamics; Interleukin-6; Intestinal Mucosa; Intestines; Ion Channels; Ischemia; Lung; Microscopy, Electron; Multiple Organ Failure; Platelet Activating Factor; Postoperative Complications; Potassium; Pulmonary Gas Exchange; Respiratory Distress Syndrome; Shock, Septic; Swine; Thromboxane A2; Tumor Necrosis Factor-alpha | 1993 |
Tyrosine-kinase activity in rabbit platelets stimulated with platelet-activating factor. The effect of inhibiting tyrosine kinase with genistein on platelet-signal-molecule elevation and functional responses.
Topics: Animals; Blood Platelets; Cells, Cultured; Genistein; Inositol 1,4,5-Trisphosphate; Ionomycin; Isoflavones; Phosphorylation; Phosphotyrosine; Platelet Activating Factor; Protein-Tyrosine Kinases; Rabbits; Signal Transduction; Tetradecanoylphorbol Acetate; Thrombin; Thromboxane A2; Type C Phospholipases; Tyrosine | 1993 |
Increased prostaglandin I2 and thromboxane A2 production by rat dental pulp after intravenous administration of endotoxin.
Topics: Animals; Arachidonic Acid; Azepines; Dental Pulp; Endotoxins; Epoprostenol; Escherichia coli; Indomethacin; Injections, Intravenous; Jejunum; Lung; Male; Platelet Activating Factor; Rats; Rats, Wistar; Thromboxane A2; Time Factors; Triazoles | 1994 |
[Pharmacological profile of F-0401, a novel dihydropyridine derivative. III. The anti-aggregatory action of F-0401 on rabbit platelets].
Topics: Animals; Cells, Cultured; Dihydropyridines; Male; Platelet Activating Factor; Platelet Aggregation Inhibitors; Rabbits; Thromboxane A2 | 1995 |
Role of thromboxane A2 and platelet-activating factor in allergic bronchoconstriction in guinea pig airway in vivo.
Topics: Administration, Inhalation; Animals; Antigens; Asthma; Azepines; Bridged Bicyclo Compounds; Bronchoconstriction; Dose-Response Relationship, Drug; Fatty Acids, Monounsaturated; Guinea Pigs; Hypersensitivity; Male; Platelet Activating Factor; Receptors, Prostaglandin; Thromboxane A2; Triazoles | 1995 |
Antiplatelet actions of 2-(4-[1-(2-chlorophenyl) piperazinyl]) methyl-2,3-dihydroimidazo[1,2-c]quinazolin-5(6H)-one compound.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Arachidonic Acid; Blood Platelets; Calcium; Collagen; Cyclic AMP; Epinephrine; Fibrinogen; Humans; Imidazoles; Pancreatic Elastase; Phosphatidylinositols; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Prostaglandin Endoperoxides, Synthetic; Quinazolines; Rabbits; Receptors, Cell Surface; Signal Transduction; Thromboxane A2; Thromboxane B2 | 1995 |
Platelet-activating factor increases vascular resistance in rat hindquarters by thromboxane A2.
Topics: Animals; Azepines; Blood Pressure; Capillary Permeability; Hindlimb; Ibuprofen; Male; Phenylacetates; Platelet Activating Factor; Rats; Rats, Wistar; Regional Blood Flow; Sulfonamides; Thromboxane A2; Thromboxanes; Triazoles; Vascular Resistance | 1995 |
Sequential agonist activation and site-specific mediation of acute cyclosporine constriction in rat renal arterioles.
Topics: Animals; Arterioles; Bridged Bicyclo Compounds, Heterocyclic; Cyclosporine; Endothelin Receptor Antagonists; Endothelins; Fatty Acids, Unsaturated; Furans; Hydrazines; Kidney; Peptides, Cyclic; Platelet Activating Factor; Prostaglandins H; Rats; Rats, Sprague-Dawley; Receptors, Thromboxane; Thromboxane A2; Vasoconstriction; Vasoconstrictor Agents | 1994 |
DP-1904, a specific inhibitor of thromboxane A2 synthesizing enzyme, suppresses ICAM-1 expression by stimulated vascular endothelial cells.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Cell Division; Cells, Cultured; Cycloheximide; Endothelium, Vascular; Epoprostenol; Fluorescein-5-isothiocyanate; Fluorescent Antibody Technique; Humans; Imidazoles; Intercellular Adhesion Molecule-1; Interleukin-1; Platelet Activating Factor; Prostaglandin Endoperoxides, Synthetic; Recombinant Proteins; Tetrahydronaphthalenes; Thrombin; Thromboxane A2; Thromboxane-A Synthase; Tumor Necrosis Factor-alpha; Umbilical Veins | 1994 |
The effects of aspirin and paracetamol on the aggregation of equine blood platelets.
Topics: Acetaminophen; Adenosine Diphosphate; Animals; Arachidonic Acid; Aspirin; Blood Platelets; Cell Size; Collagen; Dose-Response Relationship, Drug; Horses; In Vitro Techniques; Nephelometry and Turbidimetry; Platelet Activating Factor; Platelet Aggregation; Prostaglandin Endoperoxides, Synthetic; Thromboxane A2 | 1994 |
Interactions of constitutive nitric oxide with PAF and thromboxane on rat intestinal vascular integrity in acute endotoxaemia.
Topics: Animals; Azepines; Blood Pressure; Capillaries; Capillary Permeability; Cyclooxygenase Inhibitors; Diterpenes; Escherichia coli; Ginkgolides; Intestinal Mucosa; Intestines; Lactones; Lipopolysaccharides; Male; Nitric Oxide; Phenylephrine; Platelet Activating Factor; Platelet Membrane Glycoproteins; Rats; Rats, Wistar; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Receptors, Thromboxane; Thromboxane A2; Triazoles | 1994 |
TNF potentiates PAF-induced pulmonary vasoconstriction in the rat: role of neutrophils and thromboxane A2.
Topics: Animals; Blood Pressure; Drug Synergism; Imidazoles; In Vitro Techniques; Lipopolysaccharides; Male; Neutropenia; Neutrophils; Platelet Activating Factor; Pulmonary Circulation; Rats; Rats, Sprague-Dawley; Thromboxane A2; Thromboxane-A Synthase; Tumor Necrosis Factor-alpha; Vasoconstriction | 1994 |
Endothelin-1-induced myocardial ischaemia and oedema in the rat: involvement of the ETA receptor, platelet-activating factor and thromboxane A2.
Topics: Anesthesia; Animals; Blood Pressure; Capillary Permeability; Edema; Electrocardiography; Endothelin Receptor Antagonists; Endothelins; Heart Rate; In Vitro Techniques; Male; Myocardial Ischemia; Platelet Activating Factor; Platelet Membrane Glycoproteins; Rats; Rats, Wistar; Receptors, Cell Surface; Receptors, Endothelin; Receptors, G-Protein-Coupled; Receptors, Thromboxane; Thromboxane A2 | 1994 |
Inhibition of antigen-induced airway hyperresponsiveness in rats: effects of ozagrel (a thromboxane A2 synthase inhibitor) and of CV-3988 (a platelet activating factor antagonist).
Topics: Acetylcholine; Animals; Antigens, Helminth; Ascaris; Bronchial Hyperreactivity; Dinitrobenzenes; Lung; Male; Methacrylates; Phospholipid Ethers; Platelet Activating Factor; Rats; Rats, Wistar; Respiration; Thromboxane A2; Thromboxane-A Synthase; Vaccination | 1994 |
IL-1 beta regulates the expression of the Gi2 alpha gene via lipid mediators in guinea pig tracheal muscle.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Gene Expression Regulation; GTP-Binding Proteins; Guinea Pigs; Humans; Hydroxyeicosatetraenoic Acids; Indomethacin; Interleukin-1; Leukotriene D4; Lipids; Lipoxygenase Inhibitors; Masoprocol; Muscle, Smooth; Platelet Activating Factor; Prostaglandin Endoperoxides, Synthetic; Recombinant Proteins; Thromboxane A2; Trachea; Vasoconstrictor Agents | 1994 |
Enhancement of thrombotic arterial occlusion following cholesterol feeding in the guinea-pig: a role for thromboxane A2.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Animals; Arterial Occlusive Diseases; Cholesterol, Dietary; Collagen; Femoral Artery; Guinea Pigs; Male; Photochemistry; Platelet Activating Factor; Platelet Aggregation; Prostaglandin Endoperoxides, Synthetic; Thrombosis; Thromboxane A2; Time Factors | 1994 |
Pharmacological studies of platelet-activating factor (PAF)-induced augmentation of response to histamine in guinea-pigs.
Topics: Animals; Benzoquinones; Bridged Bicyclo Compounds; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Capillary Permeability; Chromones; Drug Interactions; Fatty Acids, Monounsaturated; Guinea Pigs; Histamine; Indomethacin; Leukocyte Count; Leukotriene Antagonists; Lipoxygenase Inhibitors; Male; Methacrylates; Phospholipid Ethers; Platelet Activating Factor; Pressure; Respiratory Physiological Phenomena; Respiratory System; Thromboxane A2 | 1994 |
Influence of co-incubation and cell number of platelets and polymorphonuclear leukocytes in cellular inhibition and activation phenomena.
Topics: Blood Platelets; Cell Communication; Humans; Leukocyte Count; Neutrophils; Platelet Activating Factor; Platelet Activation; Platelet Aggregation; Platelet Count; Thromboxane A2; Thromboxane B2 | 1994 |
Effects of CS-518, a thromboxane synthase inhibitor, on eosinophil function.
Topics: Animals; Asthma; Bronchoalveolar Lavage Fluid; Chemotaxis, Leukocyte; Eosinophils; Epoprostenol; Guinea Pigs; In Vitro Techniques; Male; Peroxidases; Platelet Activating Factor; Pulmonary Alveoli; Superoxides; Thiophenes; Thromboxane A2; Thromboxane-A Synthase | 1993 |
[Relation of platelet activating factor induced airway hyperresponsiveness to thromboxane A2 and neutrophil in dogs].
Topics: Animals; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Dogs; Female; Neutrophils; Platelet Activating Factor; Thromboxane A2 | 1993 |
Tumor necrosis factor-alpha mediates endotoxin-induced lung injury in platelet activating factor-primed rats.
Topics: Animals; Antibodies, Monoclonal; Bronchoalveolar Lavage Fluid; Capillary Permeability; Cricetinae; Indomethacin; Leukocyte Count; Leukocytes; Lipopolysaccharides; Lung; Lung Diseases; Male; Organ Size; Peroxidase; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Thromboxane A2; Time Factors; Tumor Necrosis Factor-alpha | 1993 |
Platelet-activating factor-induced enhancement of superoxide anion generation in guinea-pigs.
Topics: Animals; Azepines; Guinea Pigs; Injections, Intravenous; Luminescent Measurements; Macrophages, Alveolar; Male; Neutrophils; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Receptors, Thromboxane; Superoxides; Thromboxane A2; Triazoles | 1993 |
Human platelets secrete chemotactic activity for eosinophils.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Azepines; Blood Platelets; Calcium; Chemotactic Factors; Chemotaxis, Leukocyte; Cytoplasmic Granules; Cytosol; Eosinophils; Humans; Platelet Activating Factor; Platelet Factor 4; Platelet Storage Pool Deficiency; Prostaglandin Endoperoxides; Thromboxane A2; Triazoles | 1993 |
Roles of platelet-activating factor, thromboxane A2, ADP and thrombin in thrombogenesis in the guinea pig.
Topics: Adenosine Diphosphate; Animals; Azepines; Biphenyl Compounds; Guinea Pigs; Heptanoic Acids; Male; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Thrombin; Thromboxane A2; Ticlopidine; Triazoles | 1993 |
11-Dehydro thromboxane B2: a reliable parameter of thromboxane A2 production in dogs.
Topics: Animals; Dogs; Female; Lung; Male; Platelet Activating Factor; Reproducibility of Results; Thromboxane A2; Thromboxane B2; Vascular Resistance | 1993 |
Abnormal inside-out signal transduction-dependent activation of glycoprotein IIb-IIIa in a patient with impaired pleckstrin phosphorylation.
Topics: Adenine Nucleotides; Adolescent; Antibodies, Monoclonal; Blood Proteins; Fibrinogen; Flow Cytometry; Humans; Male; Phosphoproteins; Phosphorylation; Platelet Activating Factor; Platelet Aggregation; Platelet Glycoprotein GPIIb-IIIa Complex; Protein Kinase C; Serotonin; Signal Transduction; Thrombin; Thromboxane A2 | 1996 |
Platelet-activating factor and not thromboxane A2 is an important mediator of endotoxin-induced platelet aggregation in equine heparinised whole blood in vitro.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Azepines; Carbazoles; Clonixin; Endotoxins; Heparin; Horses; In Vitro Techniques; Phospholipases A; Phospholipases A2; Phospholipid Ethers; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Quinacrine; Thromboxane A2; Triazoles | 1996 |
Studies on the effects of agonists and antagonists on platelet shape change and platelet aggregation in whole blood.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Adenosine Triphosphate; Azepines; Blood Platelets; Humans; In Vitro Techniques; Piperazines; Piperidines; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Prostaglandin Endoperoxides, Synthetic; Serotonin; Succinates; Sulfonamides; Thromboxane A2; Triazoles; Vasoconstrictor Agents | 1996 |
Cyclooxygenase-2-dependent bronchoconstriction in perfused rat lungs exposed to endotoxin.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 6-Ketoprostaglandin F1 alpha; Animals; Bronchoconstriction; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; DNA Primers; Endotoxins; Female; In Vitro Techniques; Isoenzymes; Lipopolysaccharides; Lipoxygenase Inhibitors; Lung; Microscopy, Electron, Scanning; Platelet Activating Factor; Polymerase Chain Reaction; Prostaglandin Endoperoxides, Synthetic; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar; RNA, Messenger; Salmonella; Thromboxane A2; Thromboxane B2; Transcription, Genetic; Vasoconstrictor Agents | 1996 |
Role of platelet-activating factor and thromboxane A2 in radical production during ischemia and reperfusion of the rat brain.
Topics: Animals; Ascorbic Acid; Azepines; Brain; Brain Ischemia; Bridged Bicyclo Compounds; Dehydroascorbic Acid; Extracellular Space; Fatty Acids, Monounsaturated; Free Radicals; Male; Oxygen; Partial Pressure; Peroxidase; Platelet Activating Factor; Platelet Aggregation Inhibitors; Rats; Rats, Wistar; Reactive Oxygen Species; Reperfusion; Thromboxane A2; Triazoles | 1996 |
Thromboxane rather than platelet activating factor mediates pulmonary vasoconstriction after antigen challenge in rabbits.
Topics: Anesthesia; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antigens; Enzyme Inhibitors; Humans; Immunization; Indomethacin; Lung; Methacrylates; Platelet Activating Factor; Pulmonary Artery; Pulmonary Circulation; Pyridinium Compounds; Rabbits; Thromboxane A2; Thromboxane-A Synthase; Vasoconstriction | 1996 |
Thromboxane A2 receptor blockade suppresses intercellular adhesion molecule-1 expression by stimulated vascular endothelial cells.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Bridged Bicyclo Compounds, Heterocyclic; Cells, Cultured; Cyclic AMP; Endothelium, Vascular; Enzyme Inhibitors; Fatty Acids, Unsaturated; Humans; Hydrazines; Intercellular Adhesion Molecule-1; Platelet Activating Factor; Prostaglandin Endoperoxides, Synthetic; Protein Kinase Inhibitors; Protein Kinases; Radioligand Assay; Receptors, Thromboxane; Thromboxane A2; Tumor Necrosis Factor-alpha | 1996 |
Effects of 1-[3-(4-benzhydryl-1-piperazinyl)propyl]-3- (1H-imidazol-1-ylmethyl)-1H-indole-6-carboxylic acid with thromboxane A2 synthetase inhibitory and H1-blocking activities on anaphylactic bronchospasm.
Topics: Anaphylaxis; Animals; Bronchial Spasm; Bronchoconstriction; Enzyme Inhibitors; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Indoles; Leukotriene D4; Lung; Male; Methacrylates; Platelet Activating Factor; Rabbits; Thromboxane A2; Thromboxane-A Synthase; Trachea | 1996 |
Eicosanoid production from porcine neutrophils and platelets: differential production with various agonists.
Topics: Animals; Blood Platelets; Calcimycin; Cell Communication; Complement C5a; Cytochalasin B; Eicosanoids; Humans; Hydroxyeicosatetraenoic Acids; In Vitro Techniques; Lipoxins; Male; Neutrophils; Platelet Activating Factor; Pyridinium Compounds; Recombinant Proteins; Swine; Thromboxane A2 | 1997 |
Anti-thrombotic and anti-inflammatory activities of protopine.
Topics: Adenosine Diphosphate; Alkaloids; Animals; Anti-Inflammatory Agents; Arachidonic Acid; Benzophenanthridines; Berberine Alkaloids; Blood Platelets; Carrageenan; Edema; Fibrinolytic Agents; Histamine H1 Antagonists; Male; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Prostaglandin-Endoperoxide Synthases; Rabbits; Rats; Rats, Sprague-Dawley; Thromboxane A2 | 1997 |
[Effect of platelet activating factor on TxA2, PGI2 and Ca(2+)-ATPase activity in the intra-pulmonary artery smooth muscle cells].
Topics: Animals; Calcium-Transporting ATPases; Cells, Cultured; Epoprostenol; Indomethacin; Muscle, Smooth, Vascular; Platelet Activating Factor; Pulmonary Artery; Rabbits; Thromboxane A2; Verapamil | 1996 |
Activation of platelets in bronchial asthma.
Topics: Administration, Oral; Adult; Aged; Asthma; Blood Platelets; Bronchodilator Agents; Calcium; Case-Control Studies; Chemokine CCL5; Female; Gene Expression Regulation; Humans; Male; Middle Aged; P-Selectin; Platelet Activating Factor; Platelet Activation; Theophylline; Thrombin; Thromboxane A2 | 1998 |
Modulation of platelet activating factor-induced glycogenolysis in the perfused rat liver after administration of endotoxin in vivo.
Topics: Animals; Eicosanoids; Endotoxemia; Glycogen; Leukotriene Antagonists; Leukotriene D4; Lipopolysaccharides; Liver; Male; Membrane Proteins; Oxygen Consumption; Perfusion; Platelet Activating Factor; Prostaglandin D2; Rats; Rats, Sprague-Dawley; Receptors, Immunologic; Receptors, Leukotriene; Receptors, Prostaglandin; Receptors, Thromboxane; Thromboxane A2 | 1998 |
[The effect of platelet activating factor on the biosynthesis of thromboxane A2 and prostaglandin I2 in human placental villi and umbilical artery].
Topics: 6-Ketoprostaglandin F1 alpha; Adult; Chorionic Villi; Epoprostenol; Female; Humans; Platelet Activating Factor; Pregnancy; Thromboxane A2; Umbilical Arteries | 1997 |
Effect of platelet activation on coronary collateral blood flow.
Topics: Animals; Blood Platelets; Collateral Circulation; Coronary Circulation; Dogs; Myocardial Ischemia; Platelet Activating Factor; Platelet Activation; Thromboxane A2; Vasoconstriction | 1998 |
Role of thromboxane A2 and platelet activating factor in early haemodynamic response to lipopolysaccharide in rats.
Topics: Animals; Azepines; Blood Pressure; Enzyme Inhibitors; Escherichia coli; Indans; Lipopolysaccharides; Male; Platelet Activating Factor; Platelet Aggregation Inhibitors; Rats; Rats, Wistar; Thromboxane A2; Triazoles | 1999 |
Early bronchial hyperresponsiveness following injection of sephadex beads in the guinea pig: involvement of platelet activating factor and thromboxane A2.
Topics: Acetylcholine; Animals; Bronchial Hyperreactivity; Dextrans; Guinea Pigs; Indicators and Reagents; Platelet Activating Factor; Thromboxane A2; Vasodilator Agents | 1999 |
Endotoxaemia in rats: role of NO, PAF and TXA2 in pulmonary neutrophil sequestration and hyperlactataemia.
Topics: Animals; Azepines; Cell Movement; Endotoxemia; Indans; Lactic Acid; Lipopolysaccharides; Lung; Male; Neutrophils; NG-Nitroarginine Methyl Ester; Nitric Oxide; Platelet Activating Factor; Platelet Membrane Glycoproteins; Rats; Rats, Wistar; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Thromboxane A2; Triazoles | 1999 |
Platelet-activating factor and arachidonic acid metabolites mediate tumor necrosis factor and eicosanoid kinetics and cardiopulmonary dysfunction during bacteremic shock.
Topics: Aeromonas hydrophila; Animals; Arachidonic Acid; Azepines; Bridged Bicyclo Compounds, Heterocyclic; Eicosanoids; Female; Gram-Negative Bacterial Infections; Heart Diseases; Hemodynamics; Hypertension, Pulmonary; Lipoxygenase Inhibitors; Masoprocol; Oxazoles; Oxygen; Oxygen Consumption; Platelet Activating Factor; Prostaglandin-Endoperoxide Synthases; Shock, Septic; Swine; Thromboxane A2; Triazoles; Tumor Necrosis Factor-alpha | 1999 |
Biphasic response to lipopolysaccharide from E. coli in the isolated ventilated blood-perfused rat lung.
Topics: Animals; Bronchoconstrictor Agents; Bronchodilator Agents; Enzyme Inhibitors; Escherichia coli; In Vitro Techniques; Lipopolysaccharides; Lung; Perfusion; Platelet Activating Factor; Platelet Aggregation Inhibitors; Rats; Rats, Wistar; Respiration; Thromboxane A2; Vasoconstrictor Agents | 1999 |
Platelet-activating factor contributes to postischemic vasospasm.
Topics: Animals; Genitalia, Male; Injections, Intra-Arterial; Ischemia; Male; Microcirculation; Muscle, Skeletal; Nitric Oxide; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Thromboxane A2; Time Factors; Vasoconstriction | 2000 |
Mechanisms of Helicobacter pylori-induced rat gastric mucosal microcirculatory disturbances in vivo.
Topics: Animals; Arginine; Blood Platelets; Dinoprostone; Gastric Mucosa; Helicobacter pylori; Histamine H1 Antagonists; Ketotifen; Leukocytes; Leukotriene B4; Male; Microcirculation; Microscopy, Fluorescence; Platelet Activating Factor; Platelet Aggregation Inhibitors; Pyrilamine; Rats; Rats, Wistar; Serum Albumin; Thromboxane A2 | 2000 |
Analysis of cardiac function during hyperacute rejection: effects of PAF antagonist, TXA(2) inhibitor/antagonists, and nitroglycerin.
Topics: Animals; Electric Stimulation; Enzyme Inhibitors; Fatty Acids, Monounsaturated; Graft Rejection; Guinea Pigs; Heart Transplantation; In Vitro Techniques; Isoquinolines; Nitroglycerin; Platelet Activating Factor; Platelet Aggregation Inhibitors; Pyridines; Pyridinium Compounds; Rats; Rats, Inbred Strains; Tetrahydroisoquinolines; Thromboxane A2; Transplantation, Heterologous; Ventricular Function, Left | 2000 |
Thromboxane A(2)-mediated Cl(-) secretion induced by platelet-activating factor in isolated rat colon.
Topics: 5-Lipoxygenase-Activating Proteins; Animals; Benzimidazoles; Benzoxepins; Carrier Proteins; Chlorides; Colon; Dinoprostone; Enzyme Inhibitors; Female; Imidazoles; In Vitro Techniques; Indoles; Intestinal Mucosa; Lipoxygenase Inhibitors; Membrane Proteins; Platelet Activating Factor; Platelet Aggregation Inhibitors; Rats; Rats, Wistar; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP1 Subtype; Receptors, Thromboxane; Secretory Rate; Thromboxane A2; Thromboxane-A Synthase | 2000 |
Role of chemical mediators in airway hyperresponsiveness in an asthmatic model.
Topics: Airway Resistance; Animals; Asthma; Bronchial Hyperreactivity; Disease Models, Animal; Dose-Response Relationship, Drug; Guinea Pigs; Histamine; Indomethacin; Leukotriene C4; Leukotriene D4; Male; Ovalbumin; Platelet Activating Factor; Probability; Reference Values; Sensitivity and Specificity; Thromboxane A2 | 2001 |
Molecular mechanisms involved in human platelet aggregation by synergistic interaction of platelet-activating factor and 5-hydroxytryptamine.
Topics: Diltiazem; Dose-Response Relationship, Drug; Drug Synergism; Estrenes; Flavonoids; Humans; In Vitro Techniques; Indomethacin; Kinetics; Mitogen-Activated Protein Kinases; Phosphorylation; Platelet Activating Factor; Platelet Activation; Platelet Aggregation; Pyrrolidinones; Serotonin; Thromboxane A2; Verapamil | 2001 |
Prostaglandin endoperoxides and thromboxane A2 activate the same receptor isoforms in human platelets.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Aspirin; Biphenyl Compounds; Blood Platelets; Bridged Bicyclo Compounds, Heterocyclic; Calcium Signaling; Cells, Cultured; Enzyme Inhibitors; Fatty Acids, Unsaturated; Heptanoic Acids; Humans; Hydrazines; Imidazoles; Inositol Phosphates; Kidney; Methacrylates; Phenylacetates; Platelet Activating Factor; Platelet Activation; Prostaglandin H2; Prostaglandins H; Protein Isoforms; Receptors, Thromboxane; Recombinant Fusion Proteins; Sulfonamides; Thromboxane A2; Thromboxane B2; Thromboxane-A Synthase | 2002 |
Nitric oxide-induced Cl- secretion in isolated rat colon is mediated by the release of thromboxane A2.
Topics: Animals; Camptothecin; Chlorides; Colon; Cyclic GMP; Enzyme Inhibitors; Female; Gene Expression; Imidazoles; Intestinal Mucosa; Irinotecan; Membrane Potentials; Nitric Oxide; Nitric Oxide Donors; Nitroprusside; Parasympathomimetics; Platelet Activating Factor; Platelet Aggregation Inhibitors; Rats; Rats, Wistar; RNA, Messenger; Thromboxane A2 | 2002 |
Platelet-activating factor in vasoobliteration of oxygen-induced retinopathy.
Topics: Animals; Cell Survival; Endothelium, Vascular; Humans; Hyperoxia; In Vitro Techniques; Injections; Microcirculation; Oxidative Stress; Oxygen; Pericytes; Platelet Activating Factor; Platelet Membrane Glycoproteins; Rats; Rats, Sprague-Dawley; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Retinal Diseases; Retinal Vessels; Swine; Thromboxane A2; Vitreous Body | 2002 |
Obligatory role of lipid mediators in platelet-neutrophil adhesion.
Topics: Blood Platelets; Cell Adhesion; Cells, Cultured; Hemostasis; Humans; Inflammation Mediators; Leukotrienes; Lipid Metabolism; Lipopolysaccharides; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Neutrophils; Platelet Activating Factor; Platelet Adhesiveness; Thrombin; Thromboxane A2 | 2003 |
Effects of platelet-activating factor and thromboxane A2 on isolated perfused guinea pig liver.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Bile; Capillary Permeability; Guinea Pigs; In Vitro Techniques; Infusion Pumps; Liver; Liver Circulation; Liver Diseases; Male; Organ Size; Platelet Activating Factor; Portal Vein; Reperfusion Injury; Thromboxane A2; Vascular Resistance; Vasoconstriction; Vasoconstrictor Agents | 2004 |
Propofol inhibits human platelet aggregation induced by proinflammatory lipid mediators.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Anesthetics, Intravenous; Blood Platelets; Calcium; Dose-Response Relationship, Drug; Humans; In Vitro Techniques; Inflammation Mediators; Lysophospholipids; Platelet Activating Factor; Platelet Aggregation; Propofol; Receptors, Cell Surface; Thromboxane A2 | 2004 |
Involvement of thromboxane A2 and tyrosine kinase in the synergistic interaction of platelet activating factor and calcium ionophore A23187 in human platelet aggregation.
Topics: Benzoquinones; Blood Platelets; Calcimycin; Humans; Indomethacin; Ionophores; Lactams, Macrocyclic; Platelet Activating Factor; Platelet Aggregation; Protein-Tyrosine Kinases; Quinones; Rifabutin; Thromboxane A2; Verapamil | 2004 |
Molecular surface point environments for virtual screening and the elucidation of binding patterns (MOLPRINT 3D).
Topics: Angiotensin-Converting Enzyme Inhibitors; Bayes Theorem; Corticosterone; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Ligands; Models, Molecular; Molecular Conformation; Platelet Activating Factor; Protein Binding; Quantitative Structure-Activity Relationship; Receptors, Serotonin, 5-HT3; Serotonin 5-HT3 Receptor Antagonists; Thromboxane A2 | 2004 |
Inhibitory effect of the Korean herbal medicine, Dae-Jo-Whan, on platelet-activating factor-induced platelet aggregation.
Topics: Animals; Arachidonic Acid; Dinoprostone; Dose-Response Relationship, Drug; Exocytosis; Fibrinolytic Agents; Korea; Male; Mice; Mice, Inbred ICR; Plant Extracts; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Rabbits; Thromboxane A2 | 2005 |
Biological basis and clinical implications of acetylsalicylic acid resistance.
Topics: Acetylation; Acetyltransferases; Arachidonic Acid; Aspirin; Drug Resistance; Fibrinolytic Agents; Humans; Myocardial Infarction; Platelet Activating Factor; Prostaglandin-Endoperoxide Synthases; Stroke; Thromboxane A2 | 2006 |
Effects of platelet-activating factor, thromboxane A2 and leukotriene D4 on isolated perfused rat liver.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Hemodynamics; In Vitro Techniques; Leukotriene D4; Liver; Male; Organ Size; Oxygen Consumption; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Thromboxane A2; Vasoconstriction | 2006 |
Endothelin, PAF and thromboxane A2 in allergic pulmonary hyperreactivity in mice.
Topics: Animals; Antihypertensive Agents; Bronchial Hyperreactivity; Carbachol; Endothelin B Receptor Antagonists; Endothelin-1; Endothelins; Male; Mice; Mice, Inbred BALB C; Oligopeptides; Ovalbumin; Peptide Fragments; Phospholipid Ethers; Piperidines; Platelet Activating Factor; Platelet Aggregation Inhibitors; Prostaglandin Endoperoxides, Synthetic; Receptor, Endothelin B; Thromboxane A2 | 2007 |
Role of platelet-activating factor in pneumolysin-induced acute lung injury.
Topics: Animals; Bacterial Proteins; Disease Models, Animal; Female; Humans; Hypertension, Pulmonary; Intracellular Signaling Peptides and Proteins; Mice; Mice, Inbred BALB C; Platelet Activating Factor; Pneumonia, Pneumococcal; Protein Serine-Threonine Kinases; Respiratory Distress Syndrome; rho-Associated Kinases; Signal Transduction; Streptolysins; Thromboxane A2 | 2007 |
Roles of thromboxane A2 and 5-hydroxytryptamine in endotoxin-induced digital vasoconstriction in horses.
Topics: Animals; Aspirin; Azepines; Benzamides; Blood Platelets; Calcimycin; Female; Horses; Leukocytes; Lipopolysaccharides; Male; Platelet Activating Factor; Platelet Membrane Glycoproteins; Pyridines; Receptors, G-Protein-Coupled; Serotonin; Thromboxane A2; Time Factors; Triazoles; Tryptamines; Vasoconstriction | 2008 |
Preliminary study of pulsed-electromagnetic fields effects on endothelial (HUVEC) cell secretions--modulation of the thrombo-hemorrhagic balance.
Topics: Animals; Cell Line; Electromagnetic Fields; Endothelial Cells; Epoprostenol; Hemorrhage; Humans; Platelet Activating Factor; Platelet Aggregation Inhibitors; Thrombosis; Thromboxane A2; Time Factors | 2008 |
[Influence of intensive insulin therapy on the intestinal microcirculatory dysfunction in rats with sepsis].
Topics: Animals; Disease Models, Animal; Epoprostenol; Insulin; Intestinal Mucosa; Intestines; Male; Microcirculation; Platelet Activating Factor; Random Allocation; Rats; Rats, Sprague-Dawley; Sepsis; Thromboxane A2 | 2009 |
Protective effect of dexmedetomidine against myocardial ischemia-reperfusion injury in rabbits.
Topics: Adrenergic alpha-2 Receptor Agonists; Animals; Dexmedetomidine; Disease Models, Animal; Endothelin-1; Heart Rate; Hemodynamics; Male; Myocardial Reperfusion Injury; No-Reflow Phenomenon; Platelet Activating Factor; Rabbits; Random Allocation; Reference Values; Reproducibility of Results; Thromboxane A2; Treatment Outcome | 2018 |