1-hexadecyl-2-acetyl-glycero-3-phosphocholine has been researched along with thapsigargin in 32 studies
| Studies (1-hexadecyl-2-acetyl-glycero-3-phosphocholine) | Trials (1-hexadecyl-2-acetyl-glycero-3-phosphocholine) | Recent Studies (post-2010) (1-hexadecyl-2-acetyl-glycero-3-phosphocholine) | Studies (thapsigargin) | Trials (thapsigargin) | Recent Studies (post-2010) (thapsigargin) |
|---|---|---|---|---|---|
| 9,156 | 187 | 552 | 5,234 | 3 | 918 |
| Protein | Taxonomy | 1-hexadecyl-2-acetyl-glycero-3-phosphocholine (IC50) | thapsigargin (IC50) |
|---|---|---|---|
| Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | Oryctolagus cuniculus (rabbit) | 0.002 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 21 (65.63) | 18.2507 |
| 2000's | 11 (34.38) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Clarkson, WD; Heemskerk, JW; Sage, SO; Sargeant, P | 1 |
| Randriamampita, C; Trautmann, A | 1 |
| Alvarez, J; Garcia-Sancho, J; Montero, M | 3 |
| Dohi, T; Kitayama, S; Morita, K; Okamoto, H; Shibata, K; Shirakawa, M | 1 |
| Alvarez, J; Garcia Rodriguez, C; García-Sancho, J; Montero, M; Sánchez Crespo, M | 1 |
| Grinstein, S; Laneuville, O; Nigam, S; Pace-Asciak, CR; Reynaud, D | 1 |
| Cand, F; Diserbo, M; Verdetti, J; Ziade, M | 1 |
| Mue, S; Ohuchi, K; Watanabe, M; Yamada, M | 2 |
| Dohi, T; Kitayama, S; Morita, K; Okamoto, H; Shibata, K | 1 |
| Knol, EF; Lie, WJ; Mul, FP; Roos, D; Verhoeven, AJ | 2 |
| Darbha, S; Marchase, RB | 1 |
| Herrnreiter, A; Kasugai, H; Leff, AR; Muñoz, NM; Narahashi, T; Oyaizu, M; Saito, M; Sato, R | 1 |
| Ichinowatari, G; Ohuchi, K; Tanimoto, A; Yaginuma, H; Yamada, M | 2 |
| Bost, KL; Marriott, I; Mason, MJ | 1 |
| Gardner, JP; Zhang, L | 1 |
| Bueb, JL; Tschirhart, EJ; Zardini, DM | 1 |
| Feijge, MA; Heemskerk, JW; Keularts, IM; van Gorp, RM; Vuist, WM | 1 |
| Kakuta, Y; Nara, M; Oshiro, T; Shimura, S; Shirato, K | 1 |
| Choi, SY; Ha, H; Kim, KT | 1 |
| Bjornsen, AJ; Elzi, DJ; MacKenzie, T; Silliman, CC; Wyman, TH | 1 |
| Ichinowatari, G; Ohuchi, K; Tanimoto, A; Tsuyuki, K; Yaginuma, H; Yamada, M | 2 |
| Chao, YY; Chen, IS; Chen, JJ; Chen, WC; Cheng, JS; Chou, KJ; Jan, CR; Ko, YC; Lee, KC; Liu, CP; Lo, YK; Su, W | 1 |
| Meyer, T; Teruel, MN | 1 |
| Ishiwata, M; Kato, T; Nagai, T | 1 |
| Bankers-Fulbright, JL; Bartemes, KR; Kephart, GM; Kita, H; O'Grady, SM | 1 |
| Lückhoff, A; Pantaler, E | 1 |
1 review(s) available for 1-hexadecyl-2-acetyl-glycero-3-phosphocholine and thapsigargin
| Article | Year |
|---|---|
The role of basophils in allergic disease.
Topics: Asthma; Basophils; Bronchoalveolar Lavage Fluid; Calcium; Cell Degranulation; Chymases; Complement C5a; Cytokines; Granulocyte-Macrophage Colony-Stimulating Factor; Histamine; Histamine Release; Humans; Hypersensitivity; Interleukin-3; Interleukin-5; N-Formylmethionine Leucyl-Phenylalanine; Nasal Lavage Fluid; Phorbol Esters; Platelet Activating Factor; Prostaglandin D2; Receptors, IgE; Serine Endopeptidases; Skin; Tetradecanoylphorbol Acetate; Thapsigargin; Tryptases | 1996 |
31 other study(ies) available for 1-hexadecyl-2-acetyl-glycero-3-phosphocholine and thapsigargin
| Article | Year |
|---|---|
Calcium influx evoked by Ca2+ store depletion in human platelets is more susceptible to cytochrome P-450 inhibitors than receptor-mediated calcium entry.
Topics: Adenosine Diphosphate; Blood Platelets; Calcium; Calcium Channels; Calcium-Transporting ATPases; Cell Compartmentation; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Econazole; Humans; Hydroquinones; Inositol 1,4,5-Trisphosphate; Intracellular Fluid; Ion Channel Gating; Manganese; Miconazole; Osmolar Concentration; Platelet Activating Factor; Platelet Activation; Receptors, Cholinergic; Ryanodine Receptor Calcium Release Channel; Signal Transduction; Terpenes; Thapsigargin; Thrombin; Vasopressins | 1992 |
Arachidonic acid activates Ca2+ extrusion in macrophages.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Calcium; Calcium-Transporting ATPases; Carrier Proteins; Cell Membrane; Macrophage Activation; Macrophages; Mice; Nucleotides, Cyclic; Platelet Activating Factor; Protein Kinase C; Sodium; Sodium-Calcium Exchanger; Terpenes; Thapsigargin | 1990 |
Comparative effects of cytochrome P-450 inhibitors on Ca2+ and Mn2+ entry induced by agonists or by emptying the Ca2+ stores of human neutrophils.
Topics: Calcium; Cell Membrane Permeability; Cytochrome P-450 Enzyme Inhibitors; Econazole; Fura-2; Humans; Ion Channels; Ionomycin; Manganese; Neutrophils; Nickel; Platelet Activating Factor; Terpenes; Thapsigargin | 1993 |
Agonist-induced Ca2+ influx in human neutrophils is not mediated by production of inositol polyphosphates but by emptying of the intracellular Ca2+ stores.
Topics: Calcium; Humans; In Vitro Techniques; Inositol Phosphates; Intracellular Fluid; Ion Transport; Manganese; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Terpenes; Thapsigargin | 1994 |
Regulation by protein kinase C of platelet-activating factor- and thapsigargin-induced calcium entry in rabbit neutrophils.
Topics: Alkaloids; Animals; Calcium; Calcium Chloride; Calcium-Transporting ATPases; Cytosol; Electrophysiology; Enzyme Activation; Inositol 1,4,5-Trisphosphate; Neutrophils; Platelet Activating Factor; Protein Kinase C; Rabbits; Spectrometry, Fluorescence; Staurosporine; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin | 1994 |
Dissociation of platelet-activating factor production and arachidonate release by the endomembrane Ca(2+)-ATPase inhibitor thapsigargin. Evidence for the involvement of a Ca(2+)-dependent route of priming in the production of lipid mediators by human poly
Topics: Arachidonic Acid; Calcium; Calcium-Transporting ATPases; Cell Membrane; Glycerophospholipids; Humans; In Vitro Techniques; Ionomycin; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphatidic Acids; Platelet Activating Factor; Terpenes; Thapsigargin | 1993 |
Hepoxilin A3 inhibits the rise in free intracellular calcium evoked by formyl-methionyl-leucyl-phenylalanine, platelet-activating factor and leukotriene B4.
Topics: 8,11,14-Eicosatrienoic Acid; Calcium; Calcium-Transporting ATPases; Humans; In Vitro Techniques; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Stereoisomerism; Terpenes; Thapsigargin | 1993 |
Transient inhibition by chemotactic peptide of a store-operated Ca2+ entry pathway in human neutrophils.
Topics: Biological Transport; Calcium; Calcium-Transporting ATPases; Cells, Cultured; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phorbol 12,13-Dibutyrate; Platelet Activating Factor; Terpenes; Thapsigargin | 1993 |
Stimulation of platelet-activating factor (PAF) receptors increases inositol phosphate production and cytosolic free Ca2+ concentrations in N1E-115 neuroblastoma cells.
Topics: Animals; Calcium; Calcium Channels; Calcium-Transporting ATPases; Carcinogens; Culture Media; Cytosol; Indoles; Inositol Phosphates; Lanthanum; Manganese; Mice; Neuroblastoma; Phosphatidylinositols; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Terpenes; Thapsigargin; Time Factors; Tumor Cells, Cultured | 1995 |
Enhancement by cyclo-oxygenase inhibitors of platelet-activating factor production in thapsigargin-stimulated macrophages.
Topics: Animals; Arachidonic Acid; Bucladesine; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Down-Regulation; Drug Synergism; Ibuprofen; Indomethacin; Macrophages, Peritoneal; Male; Naproxen; Platelet Activating Factor; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Terpenes; Thapsigargin | 1995 |
Ca2+ entry induced by calcium influx factor and its regulation by protein kinase C in rabbit neutrophils.
Topics: Adrenal Glands; Alkaloids; Animals; Azepines; Calcium; Calcium Channel Blockers; Cattle; Chromaffin Granules; Enzyme Inhibitors; Imidazoles; Ion Transport; Neutrophils; Platelet Activating Factor; Protein Kinase C; Rabbits; Staurosporine; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin; Triazoles | 1996 |
Regulation of intracellular calcium is closely linked to glucose metabolism in J774 macrophages.
Topics: Adenosine Triphosphate; Animals; Antimetabolites; Calcium; Cell Line; Deoxyglucose; Electric Conductivity; Endoplasmic Reticulum; Enzyme Inhibitors; Fluorescent Dyes; Fluorides, Topical; Fura-2; Glucose; Immunoglobulin G; Macrophages; Mice; Platelet Activating Factor; Rotenone; Sodium Fluoride; Thapsigargin; Uncoupling Agents | 1996 |
Platelet-activating factor production in the stimulated macrophages is enhanced by the cyclooxygenase inhibitors.
Topics: Animals; Bucladesine; Cyclooxygenase Inhibitors; Dinoprostone; Enzyme Inhibitors; In Vitro Techniques; Indomethacin; Macrophages; Macrophages, Peritoneal; Platelet Activating Factor; Rats; Stimulation, Chemical; Thapsigargin | 1996 |
Association of granular exocytosis with Ca(2+)-activated K+ channels in human eosinophils.
Topics: Calcimycin; Calcium; Chlorides; Eosinophils; Exocytosis; Humans; In Vitro Techniques; Ionomycin; Large-Conductance Calcium-Activated Potassium Channels; Membrane Potentials; Patch-Clamp Techniques; Platelet Activating Factor; Potassium Channels; Potassium Channels, Calcium-Activated; Quinidine; Sodium; Thapsigargin | 1997 |
Inhibition of tumor necrosis factor-alpha production by SK&F 98625, a CoA-independent transacylase inhibitor, in cultured rat peritoneal macrophages.
Topics: Acyltransferases; Animals; Azepines; Cells, Cultured; Dinoprostone; Enzyme Inhibitors; Furans; Imidazoles; Macrophages, Peritoneal; Male; Organophosphorus Compounds; Platelet Activating Factor; Platelet Aggregation Inhibitors; Pyridinium Compounds; Rats; Rats, Sprague-Dawley; Specific Pathogen-Free Organisms; Thapsigargin; Triazoles; Tumor Necrosis Factor-alpha | 1998 |
Degranulation of human basophils by picomolar concentrations of IL-3, IL-5, or granulocyte-macrophage colony-stimulating factor.
Topics: Basophil Degranulation Test; Basophils; Calcium; Enzyme Inhibitors; Granulocyte-Macrophage Colony-Stimulating Factor; Histamine Release; Humans; Interleukin-3; Interleukin-5; Platelet Activating Factor; Thapsigargin | 1998 |
Differential kinetics for induction of interleukin-6 mRNA expression in murine peritoneal macrophages: evidence for calcium-dependent and independent-signalling pathways.
Topics: Animals; Calcium; Interleukin-6; Kinetics; Macrophages, Peritoneal; Mice; Mice, Inbred BALB C; Platelet Activating Factor; RNA, Messenger; Signal Transduction; Thapsigargin | 1998 |
Glucocorticoid modulation of Ca2+ homeostasis in human B lymphoblasts.
Topics: B-Lymphocytes; Calcium; Calcium-Transporting ATPases; Cells, Cultured; Fura-2; Glucocorticoids; Homeostasis; Humans; Hydrocortisone; Kinetics; Manganese; Mifepristone; Platelet Activating Factor; Regression Analysis; Signal Transduction; Thapsigargin | 1999 |
Possible participation of intracellular platelet-activating factor in tumor necrosis factor-alpha production by rat peritoneal macrophages.
Topics: Animals; Azepines; Cells, Cultured; Dinoprostone; Enzyme Inhibitors; Furans; Imidazoles; Indomethacin; Macrophages, Peritoneal; Male; Organophosphorus Compounds; Platelet Activating Factor; Pyridinium Compounds; Rats; Rats, Sprague-Dawley; RNA, Messenger; Thapsigargin; Triazoles; Tumor Necrosis Factor-alpha | 1999 |
Release of O2- by human umbilical cord blood-derived eosinophils: role of intra- and extracellular calcium.
Topics: Calcium; Calcium Channel Blockers; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Inhibitors; Eosinophils; Fetal Blood; Humans; Imidazoles; Ionomycin; Magnesium; N-Formylmethionine Leucyl-Phenylalanine; Nickel; Oxygen; Platelet Activating Factor; Respiratory Burst; Spectrometry, Fluorescence; Thapsigargin | 1999 |
alpha(2A)-adrenergic receptor stimulation potentiates calcium release in platelets by modulating cAMP levels.
Topics: Adrenergic alpha-Agonists; Aspirin; Blood Platelets; Brimonidine Tartrate; Calcium; Calcium Chloride; Carbazoles; Cyclic AMP; Dose-Response Relationship, Drug; Egtazic Acid; Enzyme Inhibitors; Epinephrine; Humans; Indoles; Inositol 1,4,5-Trisphosphate; Models, Biological; Phosphorylation; Platelet Activating Factor; Platelet Activation; Platelet Glycoprotein GPIIb-IIIa Complex; Prostaglandins E; Pyrroles; Quinoxalines; Receptors, Adrenergic, alpha-2; Stimulation, Chemical; Thapsigargin; Thimerosal; Thrombin; Time Factors | 2000 |
Characterization of platelet-activating factor-induced cytosolic calcium mobilization in human eosinophils.
Topics: Calcium Signaling; Calcium-Transporting ATPases; Cytosol; Egtazic Acid; Eosinophils; Humans; Platelet Activating Factor; Protein Kinase C; Thapsigargin | 2000 |
Capsaicin inhibits platelet-activating factor-induced cytosolic Ca2+ rise and superoxide production.
Topics: Apoptosis; Biological Transport; Calcium; Calcium Signaling; Calcium-Transporting ATPases; Capsaicin; Cytosol; Enzyme Activation; Enzyme Inhibitors; HL-60 Cells; Humans; Inflammation; Platelet Activating Factor; Superoxides; Thapsigargin; Type C Phospholipases; Up-Regulation | 2000 |
Ionomycin causes activation of p38 and p42/44 mitogen-activated protein kinases in human neutrophils.
Topics: Activating Transcription Factor 2; Calcium; Calcium Signaling; Chelating Agents; Cyclic AMP Response Element-Binding Protein; DNA-Binding Proteins; Egtazic Acid; Enzyme Activation; Enzyme Inhibitors; ets-Domain Protein Elk-1; Humans; Ionomycin; Ionophores; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Platelet Activating Factor; Proto-Oncogene Proteins; Thapsigargin; Transcription Factors | 2001 |
Participation of prostaglandin E2 and platelet-activating factor in thapsigargin-induced production of interleukin-6.
Topics: Acetyltransferases; Acyl-Carrier Protein S-Acetyltransferase; Animals; Azepines; Cells, Cultured; Dinoprostone; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Inhibitors; Furans; Imidazoles; Indomethacin; Interleukin-6; Macrophages, Peritoneal; Male; Organophosphorus Compounds; Platelet Activating Factor; Platelet Membrane Glycoproteins; Rats; Rats, Sprague-Dawley; Receptors, Cell Surface; Receptors, G-Protein-Coupled; RNA, Messenger; Thapsigargin; Triazoles | 2002 |
Novel action of lignans isolated from Hernandia nymphaeifolia on Ca2+ signaling in human neutrophils.
Topics: Calcium; Calcium Signaling; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Fluorescent Dyes; Fura-2; Humans; Leukotriene B4; Lignans; Magnoliopsida; Neutrophils; Platelet Activating Factor; Thapsigargin | 2002 |
Parallel single-cell monitoring of receptor-triggered membrane translocation of a calcium-sensing protein module.
Topics: Animals; Bacterial Proteins; Calcium; Calcium Signaling; Cell Membrane; Cytosol; Fluorescence; Fluorescent Dyes; Isoenzymes; Kinetics; Luminescent Proteins; Platelet Activating Factor; Protein Binding; Protein Kinase C; Protein Structure, Tertiary; Protein Transport; Rats; Receptors, Cell Surface; Recombinant Fusion Proteins; Software; Thapsigargin; Transfection; Tumor Cells, Cultured | 2002 |
Mitochondrial calcium response in human transformed lymphoblastoid cells.
Topics: Adult; Calcium; Calcium Signaling; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Cell Line, Transformed; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Ionophores; Lymphocytes; Male; Middle Aged; Mitochondria; Platelet Activating Factor; Thapsigargin; Uncoupling Agents | 2002 |
Possible participation of intracellular platelet-activating factor in NF-kappaB activation in rat peritoneal macrophages.
Topics: Animals; Azepines; Base Sequence; Cells, Cultured; DNA Primers; Hydrolysis; Imidazoles; Lipopolysaccharides; Macrophages, Peritoneal; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; NF-kappa B; Organophosphorus Compounds; Phosphorylation; Piperidines; Platelet Activating Factor; Pyridinium Compounds; Rats; Rats, Sprague-Dawley; Thapsigargin; Triazoles | 2002 |
Platelet-activating factor stimulates cytoplasmic alkalinization and granule acidification in human eosinophils.
Topics: Adenosine Triphosphatases; Blotting, Western; Calcium; Cell Adhesion; Cell Membrane; Cells, Cultured; Cytoplasm; Cytoplasmic Granules; Cytosol; Eosinophil Granule Proteins; Eosinophil Major Basic Protein; Eosinophils; Esters; Fluoresceins; Humans; Hydrogen-Ion Concentration; Immunohistochemistry; Interleukin-5; Microscopy, Fluorescence; Oligonucleotide Array Sequence Analysis; Platelet Activating Factor; Protein Kinase C; Protons; RNA, Messenger; Tetradecanoylphorbol Acetate; Thapsigargin; Time Factors; Vacuolar Proton-Translocating ATPases; Zinc | 2004 |
Inhibitors of TRP channels reveal stimulus-dependent differential activation of Ca2+ influx pathways in human neutrophil granulocytes.
Topics: Adenosine Diphosphate Ribose; Aniline Compounds; Calcium; Cinnamates; Fluorescent Dyes; Humans; Manganese; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; ortho-Aminobenzoates; Platelet Activating Factor; Thapsigargin; TRPM Cation Channels; Xanthenes | 2009 |